TWAS hub - C6orf142

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	TCGA	Bladder Urothelial Carcinoma	0.0610	0.0330	0.0050	0.007	0.018	0.007	NA	0.008	0.077	0.0100	0.083	NA	0.0640
2	TCGA	Breast Invasive Carcinoma	0.0335	0.0185	0.0074	0.005	0.000	-0.001	NA	-0.001	0.023	0.2900	0.440	NA	0.5900
3	TCGA	Esophageal Carcinoma	0.2690	0.1040	0.0071	0.007	0.083	0.032	NA	0.052	0.180	0.0013	0.035	NA	0.0097

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3
Pulse rate, automated reading	10.6	34.4	46.4	6.8	4.0	6.4
Financial difficulties in last 2 years	7.1	9.6	11.3	-2.9	-3.4	-3.0
Arm fat mass (right)	4.9	20.3	23.2	-4.4	-4.2	-4.8
Body mass index (BMI)	4.7	20.0	24.2	-4.3	-4.2	-4.9
Overall health rating	4.7	10.1	18.1	-4.2	-2.0	-2.9
Leg fat mass (left)	4.7	18.2	25.8	-4.2	-3.3	-5.1
Comparative body size at age 10	4.5	12.5	27.7	-2.0	-5.3	-2.5
Leg fat mass (right)	4.5	17.4	24.9	-4.0	-3.3	-5.0
Loneliness, isolation	4.5	6.2	12.8	-2.3	-0.7	-3.6
Arm fat mass (left)	4.5	18.5	21.0	-4.2	-4.1	-4.6
Ovarian Cancer	4.4	5.8	8.8	-3.0	-1.7	-2.4
Trunk fat mass	4.4	18.8	25.4	-4.4	-3.4	-5.0
Hearing difficulty/problems with background noise	4.4	7.1	13.5	1.3	3.7	2.5
Emphysema/chronic bronchitis	4.4	5.0	7.5	-2.6	-0.8	-2.7
Heart disease (siblings)	4.4	5.4	8.8	-1.7	-2.1	-3.0
Depression (Nagel 2018)	4.3	6.4	10.1	-3.2	-2.2	-2.1
Weight	4.3	21.0	26.1	-4.2	-4.4	-5.1
Arm fat percentage (right)	4.3	16.8	20.9	-4.6	-3.4	-4.2
Whole body fat mass	4.3	18.1	24.4	-4.3	-3.4	-4.9
Medication: Ibuprofen	4.1	4.9	5.7	-2.0	-2.2	-2.4
Arm fat percentage (left)	4.1	16.3	20.2	-4.5	-3.4	-4.1
BMI	4.0	23.1	24.9	-4.9	-4.5	-5.0
Number of treatments/medications taken	4.0	7.1	12.9	-2.5	-1.5	-3.6
Average weekly fortified wine intake	3.9	4.6	7.1	2.0	2.7	1.6
Alcohol intake versus 10 years previously	3.8	5.7	12.3	-3.5	-0.5	-2.1
Body Mass Index (BMI) (2010)	3.6	4.9	8.6	-1.4	-2.9	-2.1
Trunk fat percentage	3.6	14.2	20.1	-4.2	-2.2	-4.5
Mouth/teeth dental problems: Bleeding gums	3.6	4.6	9.6	-3.1	-1.6	-1.3
Leg fat-free mass (left)	3.5	18.5	24.7	-3.3	-5.0	-4.5
Current tobacco smoking	3.5	5.7	7.2	-2.3	-2.1	-2.7
Leg predicted mass (left)	3.5	18.5	24.6	-3.3	-5.0	-4.5
Knee pain experienced in last month	3.5	5.4	6.7	-2.6	-2.0	-2.4
Pulse rate	3.4	5.8	7.0	2.6	1.9	2.6
Exposure to tobacco smoke at home	3.4	3.8	7.1	-2.0	-0.4	-2.7
Body fat percentage	3.3	13.2	18.1	-4.2	-2.1	-4.2
Leg fat-free mass (right)	3.3	17.5	22.5	-3.4	-4.7	-4.3
Frequency of tiredness / lethargy in last 2 weeks	3.2	5.2	7.1	-2.7	-1.9	-2.2
Systolic Blood Pressure	3.1	15.6	27.3	-5.2	-1.6	-4.1
Frequency of unenthusiasm / disinterest in last 2 weeks	3.1	4.1	6.7	-2.6	-1.6	-1.8
Impedance of leg (left)	3.1	15.1	33.2	2.3	5.8	2.6
Mouth/teeth dental problems	3.1	4.7	6.4	2.4	1.4	2.5
Medication: Ibuprofen (e.g. Nurofen)	3.1	4.0	5.5	-2.0	-2.3	-1.6
Leg predicted mass (right)	3.1	16.5	21.1	-3.3	-4.6	-4.2
Medication: Paracetamol	3.1	4.9	11.1	-3.3	-1.2	-1.4
Average weekly spirits intake	3.0	3.7	5.1	-1.8	-1.7	-2.3
Medication for pain relief, constipation, heartburn	3.0	5.1	6.9	2.6	1.3	2.6
Pack years adult smoking proportion	2.9	4.4	8.5	-1.9	-0.9	-2.9
High blood pressure	2.9	8.0	11.3	-3.4	-2.3	-2.7
Hypertension (Self-reported)	2.9	8.0	12.4	-3.5	-2.0	-2.8
Basal metabolic rate	2.9	16.0	20.5	-3.0	-4.5	-4.3
Verbal and Numeric Reasoning (VNR)	2.8	6.7	11.8	3.4	1.3	2.5
Frequency of depressed mood in last 2 weeks	2.7	3.8	4.9	-2.2	-1.5	-2.1
Hearing difficulty/problems: Yes	2.7	4.1	6.4	1.1	2.5	2.2
Impedance of leg (right)	2.7	13.0	26.0	2.5	5.1	2.7
Medication: Paracetamol	2.7	4.4	9.0	-3.0	-1.5	-1.4
Ever depressed for a whole week	2.7	3.3	4.3	1.3	2.1	2.0
Smoking Status	2.6	6.3	7.4	-2.6	-2.2	-2.7
Waist circumference	2.6	9.4	14.1	-3.0	-2.2	-3.8
Hair/balding pattern: Pattern 3	2.6	3.8	6.2	-2.5	-1.7	-1.6
Number of full brothers	2.6	3.2	6.3	-2.5	-1.2	-1.4
Leg fat percentage (left)	2.6	9.2	14.4	-3.4	-1.4	-3.8
Illnesses of siblings	2.5	3.5	8.0	0.5	1.5	2.8
Mouth/teeth dental problems: Dentures	2.5	4.3	10.6	-1.0	-1.1	-3.3
Smoking status: Current	2.5	4.0	5.5	-1.8	-1.8	-2.4
Medication: Blood pressure	2.5	4.8	8.9	-3.0	-1.4	-1.9
Seen doctor (GP) for nerves, anxiety, tension or depression	2.4	3.7	8.9	-1.3	-0.6	-3.0
Leg fat percentage (right)	2.4	8.6	13.5	-3.2	-1.5	-3.7
Health satisfaction	2.4	3.1	7.7	-2.8	-1.2	-0.5
Arm fat-free mass (left)	2.4	12.1	16.3	-2.5	-3.7	-4.0
Arm predicted mass (left)	2.4	12.3	15.8	-2.4	-3.9	-4.0
Medication: Atenolol	2.3	2.8	3.5	-1.3	-1.9	-1.9
Medication: Lansoprazole	2.3	2.6	5.9	2.4	1.4	-0.1
Mouth/teeth dental problems: Loose teeth	2.3	2.7	3.2	-1.8	-1.7	-1.4
Medication: Aspirin	2.3	2.9	6.0	-1.4	-1.0	-2.4
Pack years of smoking	2.3	3.4	6.8	-1.5	-1.1	-2.6
Systolic blood pressure, automated reading	2.2	6.4	11.0	-2.5	-1.3	-3.3
Medication: Aspirin	2.2	2.9	6.7	-1.3	-0.6	-2.6
Whole body fat-free mass	2.2	12.4	18.7	-2.2	-4.3	-3.7
Pain experienced in last month	2.2	3.7	6.8	2.6	0.7	1.9
Cardiovascular Disease	2.1	6.8	9.9	-3.1	-2.2	-2.4
Time employed in main current job	2.1	2.4	5.9	0.9	0.8	2.4
Illnesses of mother	2.1	2.6	4.3	1.1	1.5	2.1
Arm predicted mass (right)	2.1	11.0	15.1	-1.9	-3.9	-3.8
Ever had stillbirth, spontaneous miscarriage or termination	2.1	2.2	4.1	-2.0	-1.5	0.5
Whole body water mass	2.1	12.1	18.7	-2.2	-4.3	-3.6
Medication: Lisinopril	2.1	2.8	3.4	-1.5	-1.8	-1.6
Vascular/heart problems diagnosed by doctor	2.1	5.7	6.9	2.6	2.2	2.3
Impedance of whole body	2.1	10.9	22.6	1.6	4.8	2.8
High blood pressure (mother)	2.0	2.9	4.5	-1.4	-1.4	-2.1
Fluid intelligence score	2.0	4.1	8.5	2.9	1.3	1.4
Hip circumference	2.0	8.8	10.0	-3.1	-2.6	-3.2
Depression (self-reported)	2.0	2.5	4.9	-1.2	-1.0	-2.2
Exposure to tobacco smoke outside home	2.0	2.7	3.4	-1.8	-1.5	-1.6
Intelligence (Savage-Jansen 2018)	1.9	5.8	9.5	3.1	1.9	2.0
Relative age voice broke	1.8	2.8	5.2	1.4	1.1	2.3
Nervous feelings	1.8	3.3	8.5	-0.0	2.9	1.2
Father’s age at death	1.8	2.4	3.9	2.0	1.1	1.4
Arm fat-free mass (right)	1.8	9.3	12.5	-1.8	-3.5	-3.5
Chronotype (morning person)	1.7	3.9	5.5	2.3	1.0	2.3
Ever had hysterectomy (womb removed)	1.7	1.9	3.4	-1.8	0.2	-1.5
Supplements: Zinc	1.7	1.8	2.8	-1.7	0.2	-1.6
Hair/balding pattern: Pattern 2	1.7	2.2	2.6	1.6	1.5	1.3
Ever highly irritable/argumentative for 2 days	1.7	2.1	5.8	-0.1	2.4	0.6
Miserableness	1.7	3.0	4.6	-2.0	-0.6	-2.1
Depressed Affect (Nagel 2018)	1.6	3.3	4.4	-1.9	-1.3	-2.1
LDL Cholesterol	1.6	2.5	2.9	1.6	1.7	1.5
Ever unenthusiastic/disinterested for a whole week	1.6	2.0	4.8	-0.4	2.2	1.0
Trunk fat-free mass	1.6	9.3	15.8	-1.5	-4.0	-3.1
Qualifications: A levels/AS levels or equivalent	1.6	3.5	8.9	3.0	0.0	1.3
Trunk predicted mass	1.6	9.4	15.8	-1.6	-4.0	-3.1
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	1.6	1.9	5.1	-0.4	0.6	-2.2
Ever smoked	1.6	2.7	4.2	-2.0	-1.3	-1.5
Coronary Artery Disease (CAD)	1.5	1.8	3.0	-1.1	-1.7	1.1
Rheumatoid Arthritis	1.5	2.0	5.8	-2.4	-0.3	-0.4
Heel bone mineral density (BMD) T-score, automated (right)	1.5	3.4	5.4	2.1	0.4	2.3
Birth weight of first child	1.5	2.7	6.0	2.5	0.6	1.2
Mean time to correctly identify matches	1.5	2.9	6.1	2.5	0.1	1.6
Reproduciblity of spirometry measurement using ERS/ATS criteria	1.5	1.8	3.2	-1.4	0.4	-1.8
Medication: Metformin	1.4	2.0	3.5	-1.2	-1.9	-1.0
Heel bone mineral density (BMD) T-score, automated (left)	1.4	3.2	4.7	2.1	0.7	2.2
Mineral and other dietary supplements	1.4	1.8	3.6	0.9	1.0	1.9
Forced expiratory volume in 1-second (FEV1), predicted percentage	1.4	2.9	4.9	2.2	-0.3	1.9
Financial situation satisfaction	1.4	1.7	2.6	-1.5	-1.6	-0.6
Risk taking	1.4	2.1	4.7	-2.2	0.1	-1.2
Alzheimer’s Disease (in father)	1.3	1.4	3.5	-0.8	-1.9	-0.1
Diabetes (mother)	1.3	1.7	4.4	-0.7	-0.3	-2.1
Multivitamins +/- minerals	1.3	1.7	2.7	-1.4	-0.5	-1.6
Hearing aid user	1.3	1.5	2.3	0.9	1.5	1.2
Mother’s age at death	1.3	1.6	4.2	2.0	0.7	0.0
Tinnitus: Yes, now most or all of the time	1.3	1.5	1.9	-1.0	1.2	-1.4
Worry (Nagel 2018)	1.2	2.5	4.4	-1.4	2.1	1.2
Neuroticism (2016)	1.2	1.8	2.8	-1.7	-0.5	-1.5
Relative age of first facial hair	1.2	2.4	3.3	1.1	1.8	1.6
Maternal smoking around birth	1.2	1.8	4.2	-2.1	-0.3	-1.0
Fed-up feelings	1.2	2.1	2.8	-1.5	-1.1	-1.7
Chronic bronchitis/emphysema (father)	1.2	1.4	3.4	0.4	-1.8	0.8
Impedance of arm (right)	1.2	5.4	9.6	0.7	3.1	2.5
Impedance of arm (left)	1.2	5.5	7.8	0.9	2.8	2.8
Pulse wave reflection index	1.2	1.5	4.4	0.0	2.1	-0.4
Eye problems/disorders: None of the above	1.2	1.4	4.0	-0.1	2.0	0.1
Handedness (chirality/laterality): Left-handed	1.2	1.4	2.1	1.2	0.8	-1.4
Triglycerides	1.1	1.8	3.9	1.0	0.8	2.0
Alcohol usually taken with meals	1.1	1.7	2.9	1.7	-0.2	1.5
Breastfed as a baby	1.1	1.3	1.4	-1.2	-1.1	-1.2
Average weekly red wine intake	1.1	1.7	2.6	1.6	0.3	1.6
Number of operations (self-reported)	1.1	1.6	2.3	-1.0	-1.5	-1.2
Alcohol drinker status: Previous	1.1	1.3	2.9	0.4	1.7	-0.9
Schizophrenia vs Biploar Disorder	1.0	1.3	2.7	-1.1	-1.7	0.1
Schizophrenia (2014)	1.0	2.2	3.2	-1.8	-1.7	-0.7
Stomach or abdominal pain in last month	1.0	1.2	1.6	-1.2	-0.9	-1.1
Frequency of tenseness / restlessness in last 2 weeks	1.0	1.5	4.0	-2.0	0.1	-0.7
Tense / ‘highly strung’	1.0	1.6	4.1	-0.8	2.0	0.1
Medication: Ventolin 100micrograms inhaler	1.0	1.3	3.2	0.1	-0.9	-1.8
Medication: Allopurinol	1.0	1.3	3.2	-0.5	-1.8	-0.6
Ever had prostate specific antigen (PSA) test	1.0	1.1	3.2	-0.1	-1.8	0.4
Ulcerative Colitis	0.9	1.3	3.5	-0.3	-1.9	0.7
Qualifications: CSEs or equivalent	0.9	1.2	2.7	-1.6	-0.6	-0.7
Length of working week for main job	0.9	1.0	2.9	-0.2	-1.7	-0.3
Age at first live birth	0.9	1.5	4.0	0.8	2.0	-0.2
Illnesses of siblings: Diabetes	0.9	1.1	1.9	-0.3	-1.1	-1.4
Forced expiratory volume in 1-second (FEV1), predicted	0.9	2.0	2.8	-1.5	-1.7	-1.0
Eye problems/disorders: Cataract	0.9	1.1	2.5	-0.3	-1.6	0.8
Number of self-reported non-cancer illnesses	0.9	1.5	3.2	-1.8	-0.8	-0.8
Wears glasses or contact lenses	0.9	1.0	2.2	1.5	-0.4	0.9
Alcohol drinker status: Never	0.9	1.0	1.7	0.4	1.3	1.1
Age started oral contraceptive pill	0.9	1.2	2.3	1.5	-0.8	0.8
Breast Cancer	0.8	1.9	3.1	-1.8	0.4	-1.6
Ever used hormone-replacement therapy (HRT)	0.8	1.0	2.6	-0.5	-0.2	-1.6
Diabetes (father)	0.8	1.0	1.5	-1.2	0.7	-0.9
Medication: Simvastatin	0.8	1.1	2.6	-0.8	-0.4	-1.6
High blood pressure (siblings)	0.8	1.2	1.9	-0.9	-0.9	-1.4
Worry too long after embarrassment	0.8	1.3	1.9	1.0	1.0	1.4
Reason for reducing amount of alcohol drunk: Health precaution	0.8	0.9	2.6	1.6	0.2	0.0
Pulse wave peak to peak time	0.8	0.9	2.7	-0.0	-1.6	-0.0
Heart disease (mother)	0.8	0.9	1.5	0.7	-0.9	-1.2
Illness, injury, bereavement, stress in last 2 years	0.8	1.0	1.7	0.6	1.0	1.3
Smoking status: Previous	0.8	1.2	2.8	-1.7	0.3	-0.8
Commuting to job workplace: Public transport	0.8	0.9	1.0	-1.0	-0.9	1.0
Supplements: Fish oil (including cod liver oil)	0.8	1.0	1.7	1.3	-0.7	-0.9
Fractured/broken bones in last 5 years	0.8	1.0	2.8	-0.5	-0.1	1.7
Schizophrenia (2018)	0.7	1.4	2.3	-1.5	-1.1	-0.8
Reaction Time	0.7	1.4	2.6	1.6	0.4	1.2
Fasting Glucose	0.7	0.8	1.0	0.8	0.8	1.0
HDL Cholesterol	0.7	1.2	2.1	0.2	1.5	-1.1
Primary Biliary Cirrhosis	0.7	0.9	1.9	-0.9	-1.4	-0.2
Vitamin and mineral supplements	0.7	0.9	1.3	0.3	1.1	1.2
Severe depression (siblings)	0.7	0.8	1.5	-0.8	1.2	-0.3
Supplements: Glucosamine	0.7	0.9	2.4	-0.6	-0.1	-1.5
Number of incorrect matches in round	0.7	1.2	1.8	0.8	1.3	-1.0
Past tobacco smoking	0.7	1.2	2.1	1.4	0.4	1.2
Pain all over the body in last month	0.7	0.7	1.0	-1.0	-0.7	-0.8
Forced expiratory volume in 1-second (FEV1), Best measure	0.7	2.2	4.4	2.1	-0.4	1.4
Glaucoma (self-reported)	0.7	0.8	0.9	-0.9	-0.9	-0.8
Medication: Amlodipine	0.7	0.9	2.2	-0.7	0.3	-1.5
Wheeze or whistling in the chest in last year	0.7	1.3	2.6	-1.1	-0.3	-1.6
Comparative height size at age 10	0.7	3.7	8.8	-0.1	-3.0	-1.5
Suffer from ‘nerves’	0.7	1.2	3.3	-1.8	0.4	0.1
Mouth/teeth dental problems: Mouth ulcers	0.7	1.1	2.4	-0.8	1.5	-0.6
Pain type(s) experienced in last month: Hip pain	0.7	0.9	1.3	-0.8	-0.9	-1.2
Irritability	0.7	1.3	3.7	-0.1	1.9	-0.2
Unable to work because of sickness or disability	0.7	0.9	1.7	0.2	-1.0	-1.3
Ulcerative Colitis (UC)	0.6	1.2	1.6	1.1	-1.3	0.9
Allergy or Eczema	0.6	1.5	4.6	-0.1	2.1	0.2
Eye problems/disorders: Diabetes related eye disease	0.6	0.6	1.1	-0.0	-0.8	-1.1
Age when periods started (menarche)	0.6	1.5	2.6	-0.9	-1.6	-1.1
Hayfever, allergic rhinitis or eczema	0.6	1.2	3.6	-0.0	1.9	0.3
Allergy	0.6	1.3	3.6	0.1	-1.9	0.6
Neuroticism score	0.6	1.3	1.8	-1.4	0.8	-1.1
Number of live births	0.6	0.8	1.4	-1.2	-1.0	-0.2
Happiness	0.6	0.7	1.9	-1.4	0.1	0.5
Pulse wave Arterial Stiffness index	0.6	0.7	2.2	-0.0	1.5	-0.0
Medication: Blood pressure	0.6	1.0	2.8	-0.4	0.1	-1.7
Age at last live birth	0.6	0.8	2.0	0.0	1.4	-0.7
Family relationship satisfaction	0.6	0.7	0.9	-1.0	1.0	0.5
Long-standing illness, disability or infirmity	0.6	1.0	2.2	-1.5	-0.5	-0.7
Qualifications: nursing, teaching	0.6	0.9	2.1	1.4	0.6	0.6
Medication for cholesterol	0.6	0.9	1.4	1.1	1.2	0.2
Medication: Gliclazide	0.6	0.6	1.0	-1.0	-1.0	-0.2
Illnesses of father: None of the above (group 1)	0.6	0.7	1.3	0.2	0.9	1.2
Commuting to job workplace: Cycle	0.6	0.8	1.8	-0.4	-0.6	1.3
Bipolar Disorder or Schizophrenia	0.5	1.1	2.0	-1.4	-0.8	-0.8
Alzheimer’s Disease (including proxy)	0.5	0.7	1.0	-0.8	-0.8	-1.0
Major Depression (MDD)	0.5	0.7	1.0	-1.0	-0.3	-1.0
Bipolar Disorder (2011)	0.5	0.5	1.0	0.6	0.2	1.0
Other serious medical condition/disability diagnosed by doctor	0.5	0.6	0.9	-0.9	-0.4	0.9
Townsend deprivation index at recruitment	0.5	0.7	1.1	-1.0	0.1	-1.1
Had other major operations	0.5	0.7	1.7	-0.0	-1.3	0.5
Forced expiratory volume in 1-second (FEV1)	0.5	1.6	3.9	2.0	-0.2	0.9
Loud music exposure frequency	0.5	0.5	1.1	-1.0	-0.3	-0.6
Headache pain in last month	0.5	0.9	2.5	-1.6	0.2	-0.5
Qualifications: College or University degree	0.5	1.7	3.1	1.8	-0.2	1.3
Migraine (self-reported)	0.5	0.6	1.7	1.3	0.3	0.1
Medication: Seretide 50 evohaler	0.5	0.5	1.3	1.1	-0.3	-0.4
Chest pain or discomfort	0.5	0.7	1.8	-1.4	0.4	-0.4
Illnesses of father: Heart disease	0.5	0.7	1.6	-0.4	-0.5	-1.3
Friendships satisfaction	0.5	0.6	1.5	-0.3	1.2	0.5
Back pain experienced in last month	0.5	0.7	1.5	-1.2	-0.6	-0.4
Supplements: Calcium	0.5	0.5	0.6	-0.6	0.8	-0.8
Neuroticism (Nagel 2018)	0.4	0.8	2.2	-1.5	0.5	-0.2
Crohns Disease (2017)	0.4	0.9	1.6	-0.7	-0.8	-1.2
Mean Putamen Volume	0.4	0.5	1.1	1.0	0.7	-0.1
Blood White Count	0.4	2.9	5.9	-2.4	-1.2	-1.2
Type 2 Diabetes (T2D) (2018)	0.4	0.7	1.5	-0.5	-1.2	-0.6
Lung FVC	0.4	2.3	4.4	2.1	0.0	1.5
Neuroticism	0.4	1.1	1.5	-0.9	0.9	-1.2
Medication: Levothyroxine sodium	0.4	0.7	0.9	-0.9	-0.9	-0.5
Asthma	0.4	0.8	1.9	0.4	0.7	-1.4
Qualifications: O levels/GCSEs or equivalent	0.4	0.7	1.5	0.7	-1.2	-0.0
Medication for cholesterol, blood pressure or diabetes	0.4	0.7	1.9	0.3	0.3	1.4
Forced vital capacity (FVC), Best measure	0.4	1.5	3.5	1.9	-0.3	1.0
Number of children fathered	0.4	0.4	1.0	-1.0	-0.5	-0.3
Angina (self-reported)	0.4	0.5	0.9	0.6	-1.0	-0.4
Qualifications: NVQ or HND or HNC or equivalent	0.4	0.5	0.7	-0.5	-0.6	-0.8
Mood swings	0.4	0.7	1.2	-0.9	0.0	-1.1
Asthma (self-reported)	0.4	0.8	1.7	0.4	0.7	-1.3
Guilty feelings	0.4	0.6	1.0	-1.0	-0.7	-0.5
Medication: Omeprazole (e.g. Zanprol)	0.4	0.4	0.8	0.7	0.9	-0.3
Irritable Bowel Disease (IBD)	0.3	0.7	2.0	0.2	-1.4	0.0
HbA1C	0.3	0.3	0.6	0.0	0.6	0.8
Blood Red Count	0.3	2.5	4.0	-2.0	0.3	-1.8
Heel T-Score	0.3	2.6	4.1	2.0	-0.3	1.9
Waist Hip Ratio (WHR)	0.3	1.2	1.9	1.3	1.4	0.3
Hypothyroidism (self reported)	0.3	0.6	1.2	1.1	-0.7	-0.3
Diverticular disease/diverticulitis (self-reported)	0.3	0.4	0.5	0.3	0.7	-0.7
Had menopause	0.3	0.4	0.8	0.9	0.3	0.7
Forced vital capacity (FVC)	0.3	1.3	3.4	1.8	-0.1	0.8
Qualifications: None of the above	0.3	0.7	1.2	-0.0	1.1	-1.0
Diabetes (self-reported)	0.3	0.4	0.8	0.9	0.5	-0.5
Worrier / anxious feelings	0.3	0.6	1.2	-1.1	-0.1	-0.8
Falls in the last year	0.3	0.4	0.8	-0.9	-0.4	-0.6
Prospective memory result	0.3	0.3	0.6	0.8	0.1	0.6
Shortness of breath walking on level ground	0.3	0.4	0.8	-0.5	-0.9	-0.3
Had major operations	0.3	0.3	0.8	0.9	-0.3	-0.2
Diabetes diagnosed by doctor	0.3	0.5	0.8	0.7	-0.0	-0.9
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.3	0.4	0.4	0.6	0.6	-0.6
Osteoarthritis (self-reported)	0.3	0.4	0.6	-0.8	0.7	0.5
Illnesses of father: High blood pressure	0.3	0.4	0.7	0.8	0.3	0.5
Cholesterol lowering medication	0.3	0.4	1.0	0.1	-1.0	0.5
Alzheimer’s Disease (in mother)	0.2	0.3	0.5	-0.2	0.6	-0.7
Crohns Disease (2012)	0.2	0.3	0.9	0.2	-0.2	1.0
Blood Eosinophil Count	0.2	1.4	2.0	-1.4	0.5	-1.4
Respiratory disease	0.2	0.3	0.9	-0.2	0.2	-1.0
Lung FEV1/FVC ratio	0.2	1.1	2.8	1.7	-0.5	0.5
Angina	0.2	0.3	0.5	0.7	-0.6	-0.1
Medication for hormone replacement therapy	0.2	0.3	0.5	-0.0	-0.7	-0.5
Medication: Co-codamol	0.2	0.2	0.4	-0.5	-0.6	-0.3
Hand grip strength (right)	0.2	0.6	1.6	0.3	-1.3	0.2
Taking other prescription medications	0.2	0.4	0.9	-0.2	-0.4	-1.0
Sitting height	0.2	1.1	2.4	-1.0	-1.5	-0.3
Heart attack	0.2	0.2	0.4	0.6	0.4	-0.3
Hayfever/allergic rhinitis (self-reported)	0.2	0.3	0.6	-0.2	0.8	-0.4
Medication: Ramipril	0.2	0.3	0.4	-0.5	-0.4	-0.6
Noisy workplace	0.2	0.3	0.8	-0.9	-0.0	0.2
Serious illness, injury or assault of a close relative in last 2 years	0.2	0.2	0.5	0.7	0.1	-0.2
Medication: Cholesterol lowering	0.2	0.4	0.6	0.2	0.7	-0.8
Lung cancer (father)	0.2	0.2	0.5	-0.4	0.0	-0.7
Hair/balding pattern: Pattern 4	0.2	0.5	1.2	-0.1	-1.1	-0.5
Peak expiratory flow (PEF)	0.2	0.5	0.8	-0.4	-0.8	-0.9
Seen a psychiatrist for nerves, anxiety, tension or depression	0.2	0.3	0.6	-0.8	0.4	0.2
Medication: Omeprazole	0.2	0.2	0.4	0.4	0.6	-0.3
Alcohol intake frequency.	0.2	0.5	0.9	-0.9	0.7	-0.4
Number of full sisters	0.2	0.2	0.6	0.1	-0.8	-0.0
Leg pain on walking	0.2	0.2	0.6	0.1	-0.0	-0.8
Commuting to job workplace: Walk	0.2	0.2	0.5	-0.3	-0.0	0.7
Breast cancer (self-reported)	0.2	0.2	0.6	-0.2	0.2	0.8
Osteoporosis (self-reported)	0.2	0.3	0.6	-0.8	-0.2	-0.4
High cholesterol (Self-reported)	0.2	0.4	1.3	-1.1	-0.0	0.2
Medication: Bendroflumethiazide	0.2	0.3	0.5	-0.7	0.1	-0.7
Medication: Atorvastatin	0.2	0.2	0.6	0.0	0.3	0.8
Basal cell carcinoma (self-reported)	0.2	0.2	0.5	0.3	-0.7	-0.3
Deep venous thrombosis (DVT) (self-reported)	0.2	0.3	0.4	-0.5	-0.6	-0.4
Bipolar Disorder (2018)	0.1	0.1	0.1	-0.4	0.1	-0.4
Lupus	0.1	0.1	0.3	-0.5	0.2	-0.2
Type 2 Diabetes (T2D) (2012)	0.1	0.1	0.2	-0.1	-0.4	0.3
Blood Platelet Count	0.1	1.5	4.0	-0.2	2.0	0.6
Height	0.1	2.2	4.8	0.1	-2.2	-1.3
Hand grip strength (left)	0.1	0.4	1.0	0.3	-1.0	-0.2
Sensitivity / hurt feelings	0.1	0.2	0.3	0.5	-0.6	0.2
Bilateral oophorectomy (both ovaries removed)	0.1	0.1	0.3	-0.1	-0.5	0.3
Tinnitus: Yes, but not now, but have in the past	0.1	0.1	0.3	-0.5	-0.3	-0.1
Serious illness, injury or assault to yourself	0.1	0.1	0.1	-0.3	-0.3	-0.1
Standing height	0.1	1.0	1.8	-0.3	-1.4	-1.1
Blood clot in the leg (DVT)	0.1	0.1	0.2	0.0	-0.4	-0.2
Gout (self-reported)	0.1	0.2	0.5	-0.1	-0.7	-0.3
Birth weight	0.1	0.2	0.7	0.1	-0.0	-0.8
Chronic bronchitis/emphysema (mother)	0.1	0.2	0.3	-0.3	-0.6	0.1
Neck or shoulder pain in last month	0.1	0.1	0.2	-0.3	0.2	-0.5
Ever had bowel cancer screening	0.1	0.1	0.4	-0.1	0.1	-0.6
Average weekly champagne plus white wine intake	0.1	0.1	0.1	0.1	0.4	-0.3
Eye problems/disorders: Glaucoma	0.1	0.1	0.2	0.1	-0.3	0.4
Average weekly beer plus cider intake	0.1	0.2	0.3	-0.5	0.6	0.1
Myopia	0.1	0.2	0.4	0.7	0.2	0.4
Heart attack/myocardial infarction (self-reported)	0.1	0.2	0.3	0.6	0.3	-0.3
Prostate Cancer	0.0	0.0	0.0	0.0	0.0	0.0
Age at First Birth	0.0	0.1	0.1	0.4	-0.2	0.0
Hair Pigment	0.0	0.1	0.2	-0.4	0.1	-0.3
Tanning	0.0	0.4	0.9	-0.1	-0.5	0.9
Hypothyroidism/myxoedema (self-reported)	0.0	0.1	0.2	0.1	0.1	-0.5
Commuting to job workplace: Car/motor vehicle	0.0	0.0	0.1	0.3	-0.0	-0.1
Supplements: Vitamin C	0.0	0.0	0.1	0.1	-0.1	0.3
Ever taken oral contraceptive pill	0.0	0.0	0.1	-0.3	-0.1	0.2
Diastolic blood pressure, automated reading	0.0	0.1	0.2	-0.4	0.3	-0.1

Hub : Genes

C6orf142

Models

Trait associations