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chr6:118,089,396-120,041,948

Best TWAS P=2.32e-56 · Best GWAS P=5.07e-74 conditioned to 3.12e-05

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
2	GTEx	Breast Mammary Tissue (Male)	MCM9	0.21	0.00	lasso	8	-0.01	4.9e-01	-17.71	15.8	2.3e-56	-0.78	0.04	0.41	TRUE
10	The Cancer Genome Atlas	Colon Adenocarcinoma	C6orf204	0.07	0.02	enet	14	0.03	9.2e-03	10.28	-15.3	3.7e-53	0.69	0.03	0.78	TRUE
6	GTEx	Muscle Skeletal	RP11-351A11.1	0.09	0.08	enet	12	0.08	3.7e-08	2.31	8.2	2.0e-16	-0.24	0.93	0.01	TRUE
12	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	C6orf204	0.04	0.02	blup	122	0.02	1.8e-03	10.24	-6.9	4.2e-12	0.53	0.10	0.08	TRUE
1	GTEx	Artery Coronary	MCM9	0.24	-0.01	enet	34	0.00	3.7e-01	-0.12	-6.9	6.1e-12	0.37	0.05	0.25	TRUE
5	GTEx	Liver	CEP85L	0.30	0.00	enet	4	0.05	1.2e-02	13.54	-14.7	3.7e-49	0.79	0.10	0.08	FALSE
4	GTEx	Esophagus Mucosa	CEP85L	0.05	0.00	enet	6	0.01	6.8e-02	12.52	-12.7	9.7e-37	0.79	0.18	0.33	FALSE
7	METSIM	Adipose	MCM9	0.04	0.02	bslmm	415	0.02	1.4e-04	6.59	9.2	4.7e-20	-0.56	0.31	0.28	FALSE
8	NTR	Blood	PLN	0.02	0.02	bslmm	367	0.02	7.5e-06	10.43	-8.8	1.0e-18	0.38	0.90	0.02	FALSE
11	The Cancer Genome Atlas	Liver Hepatocellular Carcinoma	C6orf204	0.13	0.03	blup	113	0.05	2.1e-03	10.28	-7.1	1.3e-12	0.46	0.10	0.19	FALSE
9	ROSMAP	Brain Pre-frontal Cortex	CEP85L	0.06	0.01	bslmm	476	0.01	2.3e-02	4.56	-6.1	9.9e-10	0.60	0.18	0.42	FALSE
3	GTEx	Cells Transformed fibroblasts	MCM9	0.26	0.10	enet	41	0.11	7.2e-09	-3.66	5.8	6.5e-09	-0.16	0.99	0.00	FALSE