[Hub]/) : Traits : Pulse rate, automated reading : ← →

chr6:118,089,396-120,041,948

Best TWAS P=2.32e-56 · Best GWAS P=5.07e-74 conditioned to 3.12e-05

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Artery Coronary MCM9 0.24 -0.01 enet 34 0.00 3.7e-01 -0.12 -6.9 6.1e-12 0.37 0.05 0.25 TRUE
2 GTEx Breast Mammary Tissue (Male) MCM9 0.21 0.00 lasso 8 -0.01 4.9e-01 -17.71 15.8 2.3e-56 -0.78 0.04 0.41 TRUE
3 GTEx Cells Transformed fibroblasts MCM9 0.26 0.10 enet 41 0.11 7.2e-09 -3.66 5.8 6.5e-09 -0.16 0.99 0.00 FALSE
4 GTEx Esophagus Mucosa CEP85L 0.05 0.00 enet 6 0.01 6.8e-02 12.52 -12.7 9.7e-37 0.79 0.18 0.33 FALSE
5 GTEx Liver CEP85L 0.30 0.00 enet 4 0.05 1.2e-02 13.54 -14.7 3.7e-49 0.79 0.10 0.08 FALSE
6 GTEx Muscle Skeletal RP11-351A11.1 0.09 0.08 enet 12 0.08 3.7e-08 2.31 8.2 2.0e-16 -0.24 0.93 0.01 TRUE
7 METSIM Adipose MCM9 0.04 0.02 bslmm 415 0.02 1.4e-04 6.59 9.2 4.7e-20 -0.56 0.31 0.28 FALSE
8 NTR Blood PLN 0.02 0.02 bslmm 367 0.02 7.5e-06 10.43 -8.8 1.0e-18 0.38 0.90 0.02 FALSE
9 ROSMAP Brain Pre-frontal Cortex CEP85L 0.06 0.01 bslmm 476 0.01 2.3e-02 4.56 -6.1 9.9e-10 0.60 0.18 0.42 FALSE
10 The Cancer Genome Atlas Colon Adenocarcinoma C6orf204 0.07 0.02 enet 14 0.03 9.2e-03 10.28 -15.3 3.7e-53 0.69 0.03 0.78 TRUE
11 The Cancer Genome Atlas Liver Hepatocellular Carcinoma C6orf204 0.13 0.03 blup 113 0.05 2.1e-03 10.28 -7.1 1.3e-12 0.46 0.10 0.19 FALSE
12 The Cancer Genome Atlas Lung Squamous Cell Carcinoma C6orf204 0.04 0.02 blup 122 0.02 1.8e-03 10.24 -6.9 4.2e-12 0.53 0.10 0.08 TRUE