TWAS hub - MCM9

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.1280	0.0420	1.3e-05	0.078	0.056	0.080	0.070	0.073	9.6e-10	2.0e-07	4.9e-10	6.6e-09	2.8e-09
2	GTEx	Adipose Subcutaneous	0.1030	0.0370	2.7e-04	0.011	NA	0.021	NA	0.005	4.2e-02	NA	6.5e-03	NA	1.2e-01
3	GTEx	Artery Coronary	0.2400	0.0940	4.5e-03	-0.008	NA	-0.002	NA	-0.006	7.6e-01	NA	3.7e-01	NA	5.6e-01
4	GTEx	Breast Mammary Tissue	0.1210	0.0470	2.0e-03	-0.004	NA	-0.004	NA	0.000	5.5e-01	NA	5.8e-01	NA	3.0e-01
5	GTEx	Breast Mammary Tissue (Male)	0.2133	0.0890	7.2e-03	-0.002	NA	-0.012	NA	-0.007	3.6e-01	NA	7.8e-01	NA	4.9e-01
6	GTEx	Breast Mammary Tissue (Female)	0.1079	0.0559	2.8e-02	0.013	NA	0.023	NA	0.024	1.3e-01	NA	7.0e-02	NA	6.4e-02
7	GTEx	Cells EBV-transformed lymphocytes	0.3190	0.0770	6.4e-06	0.228	NA	0.190	NA	0.212	5.3e-08	NA	8.1e-07	NA	1.7e-07
8	GTEx	Cells Transformed fibroblasts	0.2600	0.0580	1.3e-10	0.101	NA	0.114	NA	0.096	5.2e-08	NA	7.2e-09	NA	1.2e-07
9	GTEx	Nerve Tibial	0.1764	0.0502	6.3e-06	0.079	NA	0.124	NA	0.124	3.0e-06	NA	4.7e-09	NA	4.8e-09
10	GTEx	Thyroid	0.1620	0.0480	3.2e-05	0.032	NA	0.071	NA	0.074	1.6e-03	NA	3.9e-06	NA	2.8e-06
11	METSIM	Adipose	0.0363	0.0166	1.5e-03	0.021	0.022	0.017	0.024	0.013	3.0e-04	2.4e-04	1.1e-03	1.4e-04	4.5e-03
12	TCGA	Breast Invasive Carcinoma	0.0427	0.0299	2.5e-03	0.027	0.013	0.013	NA	0.025	2.2e-06	7.7e-04	8.1e-04	NA	5.5e-06
13	TCGA	Brain Lower Grade Glioma	0.1187	0.0513	8.6e-05	0.053	0.039	0.055	NA	0.050	1.0e-06	2.7e-05	7.8e-07	NA	2.2e-06
14	TCGA	Lung Squamous Cell Carcinoma	0.0824	0.0386	1.9e-04	0.018	0.030	0.029	NA	0.020	3.7e-03	2.2e-04	3.0e-04	NA	1.9e-03
15	TCGA	Prostate Adenocarcinoma	0.0863	0.0416	8.0e-04	0.027	0.030	0.038	NA	0.028	7.0e-04	4.1e-04	7.2e-05	NA	5.2e-04

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15
Pulse rate, automated reading	10.3	33.2	249.6	4.0	4.9	-6.9	1.9	15.8	-1.4	4.8	5.8	-2.2	-0.7	9.2	-1.8	-1.4	1.9	-0.6
Pulse rate	6.4	10.7	81.4	2.5	2.0	-4.6	0.5	9.0	-1.2	2.3	2.6	-0.9	0.2	5.4	-1.2	-1.1	0.8	-0.6
Financial situation satisfaction	3.3	4.1	9.9	1.3	2.0	1.6	3.1	2.4	2.6	2.1	2.7	-0.2	1.6	1.2	1.0	1.4	2.8	2.1
Risk taking	3.1	4.5	14.3	-2.1	-0.7	-0.2	-2.7	-2.0	-1.6	-1.1	-3.8	-0.6	-2.3	-2.6	-1.3	-1.4	-3.8	-1.6
Qualifications: CSEs or equivalent	3.0	4.0	12.5	2.7	1.5	1.2	1.8	2.3	2.1	0.7	3.3	1.0	2.3	1.6	0.8	0.9	3.5	0.9
Medication: Ibuprofen	2.9	3.5	9.9	1.4	2.5	-0.7	1.2	1.3	2.3	1.6	2.8	0.1	1.0	1.1	1.6	2.0	3.1	2.3
Ever unenthusiastic/disinterested for a whole week	2.7	3.3	10.9	2.8	-1.2	0.4	-0.9	-2.1	1.8	2.7	0.6	-2.3	-0.2	-3.3	-1.6	-1.3	1.5	-0.7
Friendships satisfaction	2.7	3.4	10.2	0.8	-0.2	1.4	1.5	-0.2	3.0	1.4	1.6	0.3	2.0	-0.1	2.0	2.3	3.2	2.9
Pain type(s) experienced in last month: Hip pain	2.7	3.4	11.0	2.1	-2.2	-1.1	-0.9	-1.6	-0.8	3.3	1.0	-2.8	-1.5	-2.8	-1.9	-1.6	0.4	-0.9
Ever depressed for a whole week	2.7	3.4	8.4	1.9	-2.7	0.1	-1.8	-1.6	0.3	2.5	-1.0	-2.9	-1.2	-2.5	-2.1	-1.9	-0.1	-1.3
Bipolar Disorder (2011)	2.5	2.4	12.7	-3.6	-0.8	1.2	-0.6	-1.2	-1.1	-1.7	-2.0	1.2	-1.6	0.2	1.5	1.4	-1.5	1.1
Medication: Lansoprazole	2.5	2.8	7.9	2.8	-2.0	1.3	1.4	-0.5	1.3	1.9	2.8	-0.8	1.5	-2.1	-0.2	0.0	2.5	0.5
Ovarian Cancer	2.4	3.1	9.0	3.0	-1.0	-0.0	-0.1	-2.1	0.7	2.7	1.0	-2.5	-0.7	-2.3	-2.2	-1.9	0.8	-1.5
Supplements: Zinc	2.4	2.6	6.8	0.8	0.2	-2.6	-1.5	0.6	-0.4	1.8	-0.3	-2.5	-1.8	-0.5	-2.4	-2.3	-1.3	-1.7
Gout (self-reported)	2.4	3.3	7.8	-0.6	2.2	0.9	2.8	2.5	1.9	-0.6	0.8	1.9	2.0	1.4	2.0	2.0	1.4	2.1
Neck or shoulder pain in last month	2.4	3.3	10.2	2.9	0.2	-1.1	1.9	1.0	2.6	2.3	3.2	-0.7	1.8	0.9	-0.3	0.1	3.0	0.8
Handedness (chirality/laterality): Left-handed	2.4	2.9	8.2	1.8	-1.6	-1.8	-2.5	-0.4	-2.2	-0.1	0.2	-1.1	-1.1	-0.3	-2.3	-2.5	-0.7	-2.9
Body Mass Index (BMI) (2010)	2.3	3.2	11.5	-0.1	0.9	3.4	1.7	-2.4	1.2	0.2	1.5	1.0	1.7	-2.0	1.9	2.0	2.0	2.1
Mouth/teeth dental problems: Mouth ulcers	2.3	3.7	10.0	0.9	-1.0	-2.9	-2.0	-1.0	-0.1	0.9	-1.0	-2.0	-2.0	-0.4	-3.2	-3.1	-1.7	-2.7
HDL Cholesterol	2.2	3.7	11.3	-2.7	-0.2	-1.3	-2.4	0.3	-2.8	-2.0	-2.9	0.2	-2.4	0.5	-0.7	-0.9	-3.4	-1.2
Medication: Metformin	2.2	3.0	8.1	0.8	0.3	2.3	2.5	-1.0	1.3	0.5	2.3	1.2	1.9	-0.8	1.8	2.0	2.8	2.1
Qualifications: A levels/AS levels or equivalent	2.2	5.0	21.9	-3.8	-1.6	-0.3	-0.1	0.4	-1.6	-4.7	-2.9	3.0	0.7	1.8	2.1	1.6	-2.1	0.6
Number of full sisters	2.2	2.7	10.2	3.2	1.4	0.3	1.2	1.3	0.9	3.2	2.6	-1.3	0.6	-0.5	-0.9	-0.6	2.0	0.2
Knee pain experienced in last month	2.2	3.4	7.7	1.9	-1.6	-1.9	-1.9	-1.6	-1.1	1.9	0.5	-2.5	-1.4	-2.8	-2.4	-2.2	-0.2	-2.0
Diabetes diagnosed by doctor	2.2	3.6	10.3	0.7	-0.4	2.5	1.8	-1.5	0.6	0.3	1.9	1.5	1.6	-1.1	2.5	2.7	3.2	2.7
Pain experienced in last month	2.2	3.7	9.6	-2.5	1.2	2.0	1.3	0.2	-0.6	-2.8	-0.7	3.1	1.6	1.2	3.0	2.7	0.1	2.1
Medication: Allopurinol	2.1	2.8	8.6	-0.1	2.2	0.9	2.9	2.3	0.6	0.1	1.3	1.6	1.2	1.7	1.9	1.9	1.7	2.0
Mother’s age at death	2.1	2.7	6.8	-0.0	2.4	0.8	1.5	0.8	1.3	0.6	1.3	1.0	2.0	1.5	2.1	2.3	1.9	2.6
Age started oral contraceptive pill	2.1	2.7	7.6	-1.8	-2.3	-2.0	-2.8	-1.0	-1.5	-1.5	-2.5	-0.5	-1.4	0.1	-0.5	-0.8	-2.1	-1.0
Schizophrenia (2018)	2.0	4.2	11.8	-3.2	-1.8	0.0	-1.4	-2.1	-3.1	-3.4	-3.0	1.4	-0.7	-0.8	0.1	-0.3	-2.9	-1.3
Reaction Time	2.0	3.8	8.2	-0.7	-1.5	-1.9	-0.9	1.2	-2.1	0.7	-1.5	-2.3	-2.7	-0.8	-2.7	-2.7	-2.9	-2.4
Type 2 Diabetes (T2D) (2012)	2.0	2.3	6.2	0.2	-0.2	1.5	1.3	0.4	0.7	0.7	2.4	0.4	1.3	-0.0	2.2	2.2	2.5	2.3
High blood pressure (mother)	2.0	2.8	11.0	1.7	1.8	-1.8	0.3	1.4	1.2	2.8	3.3	-1.2	0.4	1.9	0.1	0.5	1.7	1.3
Nervous feelings	2.0	3.8	15.6	-2.3	0.8	-2.0	1.3	2.6	0.5	-1.9	-0.8	2.2	0.9	3.9	2.3	2.2	-0.6	1.6
Illnesses of mother	2.0	2.4	11.0	-0.7	-1.1	2.2	-0.6	-0.3	-0.6	-1.5	-3.3	0.0	-0.9	-0.8	-1.4	-1.7	-2.3	-2.1
Shortness of breath walking on level ground	2.0	2.4	14.4	1.2	-0.6	1.8	0.1	-1.2	0.0	2.4	0.6	-2.1	-0.7	-3.8	-1.5	-1.2	0.2	-0.4
Medication: Paracetamol	2.0	3.2	13.7	2.3	0.9	-1.2	1.3	1.3	2.4	2.8	3.7	-1.2	0.1	0.0	-0.2	0.2	2.6	0.9
Bipolar Disorder or Schizophrenia	1.9	4.7	14.2	-3.4	-2.6	-0.7	-1.9	-1.8	-3.8	-3.1	-2.9	0.7	-1.9	-0.8	0.1	-0.2	-2.7	-1.2
Fed-up feelings	1.9	3.5	9.3	0.9	-3.0	-0.6	-1.1	-0.3	-1.2	0.5	-1.5	-2.1	-1.3	-1.6	-3.0	-3.0	-1.4	-2.8
Qualifications: nursing, teaching	1.9	3.0	7.8	-2.0	-1.9	-1.2	-2.2	-0.3	-2.6	-1.8	-2.4	-0.5	-2.0	0.3	-0.8	-1.0	-2.8	-1.4
Average weekly champagne plus white wine intake	1.9	2.6	7.6	-1.1	-0.5	-2.8	-2.0	0.2	-1.8	-1.6	-2.2	-0.2	-1.1	1.6	-1.2	-1.5	-2.4	-1.8
Medication: Paracetamol	1.8	3.0	13.2	2.4	0.5	-1.2	1.7	1.2	2.0	2.8	3.6	-1.1	-0.1	0.4	-0.4	0.0	2.5	0.6
Alcohol drinker status: Previous	1.8	2.1	10.3	-0.4	-0.5	0.1	0.3	-1.1	-1.3	1.5	-0.2	-2.0	-2.3	-3.2	-1.4	-1.2	-1.2	-0.8
Schizophrenia (2014)	1.7	3.8	11.2	-2.5	-2.0	-0.3	-2.1	-2.2	-3.3	-2.5	-2.5	0.5	-1.4	-0.9	-0.5	-0.8	-2.6	-1.6
Chronotype (morning person)	1.7	3.8	15.3	-2.2	1.9	1.6	1.2	0.1	0.6	-3.9	-0.3	3.9	1.6	0.7	2.5	2.0	-0.2	1.1
Illnesses of siblings	1.7	2.3	8.4	-2.6	0.3	-0.7	-0.7	0.4	0.4	-2.9	-2.0	2.4	0.5	1.4	1.5	1.2	-1.4	0.6
Medication: Ibuprofen (e.g. Nurofen)	1.7	2.2	5.5	1.2	2.1	-1.0	1.3	1.6	1.5	1.3	2.3	-0.2	0.4	1.4	1.1	1.3	2.3	1.5
Pulse wave Arterial Stiffness index	1.7	2.0	5.1	1.4	2.3	1.4	1.1	1.2	1.4	0.8	2.1	0.7	1.5	1.5	0.8	0.9	2.1	1.0
Length of working week for main job	1.7	1.9	4.8	2.0	0.0	-0.8	-0.8	0.7	-1.2	1.2	1.1	-1.5	-1.0	-0.7	-2.2	-2.2	-0.6	-2.2
Pulse wave peak to peak time	1.7	1.9	4.8	-1.6	-2.2	-1.4	-1.0	-1.2	-1.4	-1.2	-2.1	-0.4	-1.3	-1.4	-0.5	-0.7	-2.0	-0.9
Angina (self-reported)	1.7	2.3	11.4	-0.7	-1.6	0.8	-0.6	-3.3	0.9	-0.9	-1.9	-0.2	-0.3	-3.4	-0.6	-0.7	-0.8	-0.7
Qualifications: NVQ or HND or HNC or equivalent	1.7	2.1	6.2	0.9	-0.6	-0.6	-1.9	0.4	-2.5	-0.1	-0.1	-0.5	-1.3	-0.6	-2.1	-2.3	-1.7	-2.3
Ever taken oral contraceptive pill	1.7	1.9	6.4	-1.1	-0.2	0.1	-2.5	-2.3	-1.5	-1.5	-2.1	0.5	-0.7	-0.1	-0.2	-0.5	-1.9	-1.0
Angina	1.6	2.1	11.2	-0.7	-1.4	0.5	-0.7	-3.0	0.5	-0.8	-1.7	-0.3	-0.7	-3.3	-0.8	-0.9	-1.1	-0.9
High blood pressure (siblings)	1.6	2.3	8.6	2.9	0.7	0.4	1.4	0.6	0.1	2.7	2.7	-1.7	0.3	-0.2	-1.1	-0.8	1.7	-0.4
Medication: Omeprazole	1.6	2.0	5.3	1.3	-0.9	-2.3	-1.3	-0.8	-0.7	1.9	0.3	-2.1	-2.0	-0.8	-1.7	-1.5	-0.1	-1.0
Ulcerative Colitis	1.5	2.1	9.7	-3.1	-1.0	1.2	-0.2	-0.9	-1.1	-2.0	-1.2	1.3	0.3	1.0	2.0	1.8	-0.8	1.5
Lung FEV1/FVC ratio	1.5	7.5	21.8	0.2	2.7	3.0	3.0	-1.1	3.4	3.5	2.6	0.2	1.4	-0.3	2.6	3.3	3.6	4.7
Hand grip strength (left)	1.5	3.9	10.0	-0.0	-0.4	3.0	2.6	-1.6	1.1	-0.7	1.5	2.5	3.2	-1.2	2.1	2.1	2.0	2.3
Medication: Levothyroxine sodium	1.5	2.5	5.3	0.6	1.4	0.2	1.8	2.2	1.2	-1.7	1.6	2.3	2.2	1.9	1.5	1.3	1.4	0.9
Qualifications: None of the above	1.5	3.3	10.7	2.7	-0.2	1.2	0.8	-1.8	2.4	3.3	1.7	-1.9	1.4	-2.0	-0.7	-0.2	2.7	0.7
Pain all over the body in last month	1.5	1.6	3.8	2.0	-1.1	-1.5	-1.2	-0.4	0.2	1.8	1.1	-1.7	-0.9	-0.2	-1.7	-1.5	0.3	-1.2
Fluid intelligence score	1.5	3.0	8.1	-2.6	0.7	-0.0	-0.1	-0.6	1.4	-1.7	-0.8	2.1	0.5	2.3	2.8	2.8	0.0	2.6
Exposure to tobacco smoke at home	1.5	1.7	3.3	-0.8	-1.3	-1.7	-1.4	-0.8	-1.8	-0.5	-1.1	-1.0	-1.5	-1.6	-1.1	-1.2	-1.8	-1.4
Medication: Gliclazide	1.5	1.7	4.3	0.2	1.2	0.2	1.1	-0.3	1.0	0.2	1.4	1.7	1.8	0.1	1.6	1.8	2.1	1.9
Wears glasses or contact lenses	1.5	1.7	8.4	-2.9	1.4	1.4	-0.1	0.4	0.7	-1.9	-1.4	1.0	-0.2	-0.3	1.5	1.4	-0.9	1.0
Number of treatments/medications taken	1.4	2.5	9.9	3.1	-0.4	-1.2	0.0	-0.2	1.6	2.4	2.9	-1.4	0.3	-1.2	-0.5	-0.2	2.5	0.3
Medication: Co-codamol	1.4	1.6	13.1	1.0	-1.4	-3.6	-0.8	1.0	0.0	0.2	1.6	-0.4	-0.5	-1.5	0.3	0.3	1.0	0.2
Financial difficulties in last 2 years	1.4	1.8	4.8	1.4	-1.0	1.7	2.2	-0.5	1.7	1.9	1.2	-0.7	1.0	-1.0	0.3	0.6	2.1	1.0
Diabetes (self-reported)	1.4	2.2	7.3	1.0	-0.3	2.1	1.0	-1.2	0.1	0.6	1.6	0.8	1.4	-0.5	1.8	2.1	2.7	2.1
Depression (self-reported)	1.4	1.7	5.2	1.4	0.2	0.5	2.2	0.8	2.3	1.9	1.8	-0.3	1.3	-0.2	0.1	0.4	1.7	1.1
Qualifications: O levels/GCSEs or equivalent	1.4	2.2	8.8	-1.5	-0.4	-1.9	-1.0	0.8	-1.1	-3.0	-1.8	2.2	0.3	2.1	0.8	0.4	-1.7	-0.4
Qualifications: College or University degree	1.4	4.5	15.6	-3.9	-0.1	-1.6	-1.7	0.7	-1.6	-3.9	-3.1	1.9	-1.4	1.1	0.9	0.5	-3.2	-0.4
Reproduciblity of spirometry measurement using ERS/ATS criteria	1.4	1.6	3.3	1.3	-1.2	0.6	-0.8	-1.8	-0.6	1.3	0.0	-1.4	-1.1	-1.8	-1.8	-1.7	-0.3	-1.5
Overall health rating	1.4	3.0	12.5	3.5	-1.1	-1.7	-0.1	0.6	0.1	2.8	2.2	-2.1	-0.4	-1.0	-1.8	-1.4	1.7	-1.1
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	1.4	1.6	4.1	1.9	-1.8	0.5	1.0	-0.8	2.0	1.4	0.9	-1.3	1.1	-1.8	-0.4	-0.2	1.4	0.1
Mood swings	1.4	2.5	7.8	1.9	-1.4	0.8	0.6	-0.0	0.5	2.7	1.0	-2.8	-1.0	-1.8	-2.3	-1.9	0.5	-1.2
Osteoarthritis (self-reported)	1.4	1.8	8.8	0.9	0.2	-0.9	-0.8	-0.5	-1.1	2.2	0.8	-3.0	-1.9	-1.3	-1.3	-1.1	-0.0	-0.8
Medication: Omeprazole (e.g. Zanprol)	1.4	1.7	4.0	1.8	-1.2	-1.6	-0.8	-1.3	-0.1	2.0	1.2	-1.7	-1.2	-1.6	-1.3	-1.1	0.7	-0.6
High blood pressure	1.3	3.7	17.6	3.2	0.1	0.7	0.2	1.0	0.6	4.2	3.1	-2.9	0.1	0.1	-1.2	-0.7	2.2	0.2
Mouth/teeth dental problems	1.3	2.0	5.3	-0.9	1.6	1.1	1.1	0.9	0.3	-0.4	0.7	1.6	1.0	1.3	2.3	2.3	1.2	2.2
Ever highly irritable/argumentative for 2 days	1.3	1.5	3.6	1.8	-1.9	0.0	-0.5	-1.1	0.7	1.4	0.9	-1.3	-0.6	-1.8	-1.5	-1.3	0.8	-1.1
Guilty feelings	1.3	1.9	7.7	-2.1	-1.0	-0.9	-0.7	-1.3	-1.2	-2.3	-2.8	0.8	-0.9	-0.7	-0.0	-0.3	-2.0	-0.8
Unable to work because of sickness or disability	1.3	1.7	4.0	1.8	-2.0	-1.7	0.5	-0.4	0.7	1.7	0.9	-1.8	-0.8	-2.0	-1.1	-0.9	1.1	-0.6
LDL Cholesterol	1.2	1.9	9.6	-1.1	-1.7	-0.1	-1.0	-1.7	-0.9	-1.7	-3.1	0.2	-0.6	-1.2	-0.5	-0.7	-1.8	-1.0
Type 2 Diabetes (T2D) (2018)	1.2	2.2	5.7	1.0	-0.2	1.9	1.1	-1.0	-0.1	-0.1	1.7	1.4	2.1	-0.6	1.8	1.9	2.4	1.8
Diabetes (mother)	1.2	1.5	4.3	1.0	0.2	-0.6	1.7	-0.2	1.8	0.6	2.0	1.1	1.0	-0.2	0.9	1.1	2.1	1.3
Severe depression (siblings)	1.2	1.3	3.6	-1.9	1.9	0.3	1.2	0.4	1.3	-0.2	-0.6	0.7	-0.0	1.2	1.4	1.6	-0.1	1.7
Impedance of leg (left)	1.2	5.8	19.3	-1.4	-1.4	-2.7	-2.7	0.2	-2.7	1.1	-2.4	-3.2	-4.4	-1.0	-2.2	-2.2	-3.0	-2.3
Happiness	1.2	1.4	11.3	0.6	0.9	0.3	0.6	0.2	3.4	1.3	0.4	0.1	0.6	-0.8	0.5	0.9	1.5	1.4
Health satisfaction	1.2	1.6	6.9	1.4	-0.6	-1.7	-0.0	0.7	0.7	2.6	0.9	-1.6	-0.9	-2.3	-0.8	-0.4	0.8	0.4
Mean time to correctly identify matches	1.2	2.2	4.4	-0.7	-1.4	-1.8	-0.5	0.8	-1.6	1.1	-1.6	-2.1	-1.9	-0.5	-1.9	-1.8	-2.0	-1.3
Suffer from ‘nerves’	1.2	1.8	8.0	-0.3	0.1	-1.9	1.8	2.8	0.9	-0.7	0.4	1.5	1.1	2.2	0.9	0.9	0.3	0.8
Age at last live birth	1.2	1.8	4.5	-1.3	1.3	0.7	0.6	1.1	0.5	-1.6	0.6	2.1	1.3	1.8	2.0	1.8	0.5	1.2
Average weekly red wine intake	1.2	1.7	6.3	-1.9	-0.4	0.3	-0.3	-1.3	-0.0	-2.5	-1.8	2.1	1.0	0.2	1.5	1.2	-0.8	0.8
Average weekly beer plus cider intake	1.2	1.7	7.4	0.9	-2.7	0.9	0.0	-1.8	-0.3	0.6	-0.5	-1.0	-0.2	-2.2	-1.6	-1.6	-0.7	-1.4
Vascular/heart problems diagnosed by doctor	1.2	3.2	14.7	-3.0	0.5	-1.1	-0.1	-0.2	-0.7	-3.8	-2.6	2.8	-0.1	0.9	1.1	0.7	-2.1	-0.2
Verbal and Numeric Reasoning (VNR)	1.1	2.6	8.3	-2.9	0.5	-0.2	-0.0	-0.3	0.5	-1.5	-0.6	1.7	-0.2	1.6	2.8	2.8	-0.1	2.4
Age at First Birth	1.1	1.7	5.2	-2.3	-1.0	-0.7	-0.8	-0.8	-0.8	-2.3	-1.4	1.9	0.3	0.4	1.4	1.2	-1.3	0.6
Rheumatoid Arthritis	1.1	1.5	5.7	-2.1	-0.3	-0.4	-1.0	-0.5	-0.9	-1.5	-2.1	0.2	-1.2	-0.8	-0.3	-0.6	-2.4	-0.8
Hearing difficulty/problems: Yes	1.1	1.7	8.0	0.1	-2.1	0.9	-0.9	-2.0	1.6	1.4	-1.1	-0.9	-0.4	-2.8	-0.3	-0.2	-0.2	0.5
Townsend deprivation index at recruitment	1.1	1.5	5.2	0.8	-0.7	-0.6	0.4	1.1	0.1	2.0	-0.4	-2.3	-1.8	-1.0	-1.8	-1.6	-0.4	-1.1
Frequency of unenthusiasm / disinterest in last 2 weeks	1.1	1.5	6.1	1.8	-2.5	0.5	-0.0	-0.4	1.0	1.3	-0.1	-1.1	0.5	-2.0	-1.4	-1.3	0.5	-0.9
Father’s age at death	1.1	1.4	6.8	-0.9	2.2	-0.9	-0.1	2.6	-1.5	-0.3	0.6	0.2	-0.4	2.0	0.1	0.1	-1.0	-0.0
Heart disease (mother)	1.1	1.3	3.9	-0.7	1.5	-0.8	1.5	-0.5	-0.1	-0.1	2.0	0.6	0.3	-0.4	1.5	1.7	1.4	1.6
Hypertension (Self-reported)	1.1	3.2	17.2	2.8	0.0	0.6	-0.1	0.7	0.5	4.2	3.0	-2.6	0.0	0.1	-1.0	-0.4	2.0	0.6
Illnesses of siblings: Diabetes	1.1	1.3	4.8	1.1	-1.8	0.8	0.3	-1.4	0.0	1.8	0.2	-1.7	-0.6	-2.2	-0.9	-0.8	0.3	-0.3
Long-standing illness, disability or infirmity	1.1	1.7	6.6	2.6	-1.2	-1.3	-0.8	0.7	-0.1	1.2	0.8	-1.2	-0.8	-1.7	-1.5	-1.5	0.7	-1.5
Commuting to job workplace: Public transport	1.1	1.3	3.9	-1.5	0.7	-0.8	-1.0	0.5	-1.1	-1.9	-1.6	0.1	-1.0	1.0	-0.4	-0.6	-2.0	-1.3
Diastolic blood pressure, automated reading	1.1	3.3	12.4	0.9	1.4	-1.0	0.3	3.4	0.1	2.9	2.4	-1.0	0.3	3.5	0.6	0.9	1.3	1.7
Major Depression (MDD)	1.0	1.3	6.8	0.4	0.4	-0.2	1.1	0.0	1.4	0.5	2.6	0.5	0.7	-0.7	0.9	1.0	1.9	1.2
HbA1C	1.0	1.1	3.5	-1.9	1.5	0.9	-0.3	-1.6	-0.5	-1.3	-1.1	1.2	-0.2	-0.3	1.0	1.0	-0.8	0.8
Frequency of depressed mood in last 2 weeks	1.0	1.4	3.7	1.3	-0.9	1.3	1.0	-0.4	1.7	1.9	0.2	-1.7	0.3	-1.8	-1.1	-0.9	0.5	-0.3
Systolic blood pressure, automated reading	1.0	3.0	10.8	-0.5	0.3	-0.3	0.9	1.1	1.3	0.3	1.2	1.3	1.8	3.3	2.4	2.5	1.7	2.8
Diabetes (father)	1.0	1.3	4.9	-1.5	0.8	2.2	0.9	-0.6	0.3	-1.0	-0.5	1.4	0.9	-0.2	1.6	1.5	0.2	1.1
Leg fat-free mass (left)	1.0	5.1	12.0	-0.3	1.7	3.2	2.2	-1.3	1.4	-1.6	1.6	3.5	3.0	-0.1	2.8	2.8	2.1	2.7
Hand grip strength (right)	1.0	2.7	9.6	-0.7	0.0	2.3	3.1	-0.7	0.9	-0.9	0.9	2.5	2.5	-0.8	1.7	1.6	1.0	1.8
Average weekly fortified wine intake	1.0	1.2	4.8	-2.2	0.7	-0.9	-1.2	0.4	0.3	-1.1	-1.7	0.7	-1.1	0.5	0.3	0.2	-2.0	-0.1
Tinnitus: Yes, but not now, but have in the past	1.0	1.1	4.1	1.0	0.2	-2.0	-1.3	1.0	-0.8	0.4	1.0	-1.0	-1.4	0.4	-1.1	-1.0	-0.2	-1.2
Medication: Atenolol	1.0	1.2	3.5	1.3	-0.4	-1.8	-0.7	0.7	0.3	1.8	0.6	-1.9	-1.1	0.1	-1.4	-1.2	0.1	-0.8
Leg predicted mass (left)	1.0	5.2	12.4	-0.3	1.8	3.2	2.3	-1.3	1.5	-1.7	1.6	3.5	3.1	-0.1	2.9	2.8	2.2	2.7
Had menopause	1.0	1.2	6.5	-2.5	0.0	0.1	-1.0	-0.7	1.0	0.1	-1.7	-0.7	-1.1	-0.8	0.8	1.0	-0.5	1.3
Medication: Simvastatin	1.0	1.4	5.9	1.9	-0.8	0.9	-0.1	-0.6	0.8	2.4	1.7	-1.7	-0.2	-0.6	-0.6	-0.3	1.4	0.3
Pulse wave reflection index	1.0	1.3	6.3	-0.2	1.6	2.5	1.4	-0.4	2.3	0.2	1.0	0.3	0.4	-0.2	0.5	0.6	0.7	0.7
Headache pain in last month	1.0	1.7	4.7	1.2	-0.9	-2.0	-0.4	0.5	-0.3	0.6	-0.1	-1.2	-0.8	-1.0	-2.1	-2.2	-0.7	-2.1
Medication: Amlodipine	1.0	1.4	6.0	0.9	1.2	0.9	1.3	-0.2	2.5	1.9	1.4	-0.4	0.2	-0.4	0.1	0.5	1.5	1.0
Medication for pain relief, constipation, heartburn	1.0	1.7	7.0	-2.1	-0.7	1.4	-0.9	-0.4	-1.3	-1.8	-2.6	0.9	0.1	0.6	0.4	0.1	-1.9	-0.2
Commuting to job workplace: Car/motor vehicle	1.0	1.1	3.7	1.4	0.7	-0.2	0.5	-0.3	1.6	1.9	1.6	-0.7	0.3	0.4	0.1	0.4	1.8	0.8
Illness, injury, bereavement, stress in last 2 years	1.0	1.3	3.8	-1.6	0.1	-0.3	-1.8	-0.0	-2.0	-1.4	-1.6	0.6	-0.5	0.6	-0.1	-0.3	-1.9	-0.6
Leg fat-free mass (right)	1.0	5.1	12.2	-0.3	1.7	3.1	2.4	-1.3	1.2	-1.7	1.7	3.5	3.0	-0.2	2.9	2.9	2.1	2.8
Leg predicted mass (right)	1.0	5.3	12.8	-0.4	1.7	3.1	2.3	-1.4	1.2	-1.8	1.6	3.6	3.0	-0.1	3.0	3.0	2.1	2.8
Number of self-reported non-cancer illnesses	1.0	1.7	7.0	2.6	-1.0	0.2	0.7	0.2	0.6	2.2	1.7	-1.4	-0.2	-1.3	-1.3	-1.0	1.4	-0.6
Medication: Lisinopril	1.0	1.4	7.7	0.9	1.2	-0.9	-0.3	2.3	0.2	1.0	1.4	-0.8	-0.4	2.8	-0.5	-0.4	0.1	-0.2
Commuting to job workplace: Cycle	1.0	1.2	3.0	-1.1	-0.2	1.7	-0.8	-1.5	-1.5	-1.7	-0.9	0.9	-0.1	-1.6	0.1	-0.2	-1.2	-0.5
Bipolar Disorder (2018)	0.9	1.4	4.8	-1.4	-2.0	-1.1	-1.3	-0.2	-2.2	-0.6	-0.9	-0.6	-2.1	-0.2	0.0	0.0	-0.7	-0.4
Primary Biliary Cirrhosis	0.9	1.3	6.4	-0.6	-0.0	-0.9	-1.6	-0.4	-2.5	-1.0	0.0	-0.3	-1.1	-0.2	-0.8	-1.0	-1.5	-1.5
Cardiovascular Disease	0.9	3.1	11.6	2.9	-0.0	-0.7	-0.2	1.1	0.5	3.4	2.7	-2.9	-0.1	-0.4	-2.0	-1.6	1.1	-0.8
Ever used hormone-replacement therapy (HRT)	0.9	1.1	3.4	-1.0	0.8	-0.9	-1.9	-1.3	0.3	1.3	0.1	-1.4	-1.2	-1.2	0.8	0.9	-0.2	1.2
Impedance of leg (right)	0.9	4.5	13.5	-1.1	-1.1	-2.5	-2.5	0.6	-1.8	0.9	-2.2	-2.9	-3.7	-0.7	-2.1	-2.1	-2.5	-2.2
Diverticular disease/diverticulitis (self-reported)	0.9	1.0	3.7	-0.7	-1.0	-0.4	-1.7	-0.8	-1.9	-0.0	-0.0	-1.1	-1.7	-1.2	-0.3	-0.4	-0.7	-0.5
Number of incorrect matches in round	0.9	1.4	3.3	1.3	0.5	-1.3	-0.9	0.1	0.3	1.8	1.3	-1.8	-1.5	-1.1	-1.5	-1.3	0.2	-1.0
Allergy	0.9	2.0	4.0	-0.2	1.8	1.1	1.8	2.0	2.0	-0.2	0.7	1.1	1.6	2.0	1.1	1.2	1.3	1.2
Medication: Ramipril	0.9	1.2	4.5	1.5	-1.1	0.8	-0.0	-0.9	0.4	1.7	-0.2	-1.7	-0.2	-2.1	-1.1	-0.9	0.8	-0.5
Frequency of tiredness / lethargy in last 2 weeks	0.9	1.5	5.9	2.4	-1.2	-1.0	0.9	1.3	1.6	0.9	1.8	0.2	1.5	-1.0	-0.5	-0.4	1.5	-0.1
Tense / ‘highly strung’	0.9	1.5	7.8	-0.2	2.3	-1.4	1.7	2.8	0.9	0.2	0.3	0.1	0.3	1.6	0.5	0.5	0.2	0.5
Medication: Ventolin 100micrograms inhaler	0.9	1.2	5.8	1.4	0.6	0.5	-0.2	-0.4	0.2	2.4	1.2	-1.5	-0.7	-1.4	-1.2	-0.8	0.9	-0.1
Birth weight	0.9	1.9	5.6	0.8	0.9	-0.9	1.9	1.8	2.4	1.6	1.9	-0.0	0.5	0.5	0.5	0.8	2.1	1.3
Worry (Nagel 2018)	0.8	1.6	8.6	-1.4	0.2	-1.2	1.4	1.8	0.3	-1.1	-1.0	0.9	1.0	2.9	1.0	0.9	-0.6	0.7
Neuroticism (2016)	0.8	1.2	4.7	-0.2	0.1	-1.8	1.0	2.1	0.1	-0.7	0.7	1.4	0.8	2.2	0.6	0.5	0.2	0.5
BMI	0.8	4.4	11.3	0.8	0.7	3.4	1.8	-2.3	2.7	1.4	2.1	1.3	1.9	-2.6	1.6	1.9	2.4	2.7
Ever had hysterectomy (womb removed)	0.8	0.9	2.3	1.3	1.1	-1.5	-0.5	0.6	-0.0	1.4	0.7	-1.5	-0.3	0.0	-1.3	-1.1	-0.2	-0.7
Eye problems/disorders: Diabetes related eye disease	0.8	0.9	2.9	0.9	-0.5	1.2	1.4	-0.8	-0.2	0.2	1.6	0.9	0.7	-0.1	0.6	0.8	1.7	0.9
Taking other prescription medications	0.8	1.2	4.7	2.2	-1.3	-1.4	-0.2	0.2	0.7	1.4	1.4	-1.2	-0.2	-1.1	-0.9	-0.8	1.0	-0.5
Mouth/teeth dental problems: Dentures	0.8	1.4	4.2	1.2	-2.1	0.2	-0.6	-1.8	-0.1	0.5	-0.3	-1.2	0.4	-2.0	-1.4	-1.4	-0.2	-1.1
Loud music exposure frequency	0.8	0.9	3.5	-1.9	-1.0	1.4	1.0	0.1	-0.5	-1.3	-1.5	0.8	0.0	0.0	0.6	0.5	-1.0	0.5
Medication: Blood pressure	0.8	1.4	7.8	1.9	0.5	0.5	0.3	0.5	0.6	2.8	1.2	-1.9	-0.5	-0.2	-0.8	-0.5	1.1	0.1
Alcohol intake frequency.	0.8	1.9	7.2	1.8	0.8	1.0	1.4	0.3	1.6	2.7	1.9	-1.6	-0.4	-1.5	-0.5	-0.2	1.7	0.4
Chest pain or discomfort	0.8	1.1	4.4	0.0	-1.3	-1.0	-1.8	-1.9	0.4	-0.2	-0.5	-0.7	-0.6	-2.1	-0.6	-0.6	-0.5	-0.9
Whole body fat-free mass	0.8	4.8	9.9	0.1	1.4	3.0	2.5	-1.4	1.8	-1.4	1.8	3.1	3.0	-0.5	2.6	2.6	2.4	2.5
Osteoporosis (self-reported)	0.8	1.0	6.9	0.2	-1.8	-2.6	0.6	1.1	-0.1	-0.3	0.1	0.5	0.4	1.5	0.2	0.2	0.3	0.1
Whole body water mass	0.8	4.8	9.5	0.2	1.4	3.0	2.4	-1.4	1.8	-1.3	1.9	3.1	3.0	-0.5	2.6	2.6	2.5	2.5
Eye problems/disorders: Glaucoma	0.8	0.9	2.4	0.6	-0.2	-0.2	-0.9	-0.1	-1.2	0.7	-0.0	-1.2	-0.9	-0.6	-1.5	-1.5	-1.2	-1.5
Illnesses of father: High blood pressure	0.8	0.9	2.6	0.5	-1.3	-0.5	0.8	1.6	0.1	1.4	1.5	-1.6	-0.8	-0.4	-0.9	-0.7	0.3	-0.3
Basal metabolic rate	0.8	4.3	9.7	-0.1	1.4	3.1	2.1	-1.6	1.3	-1.2	1.8	2.9	2.5	-0.8	2.5	2.5	2.2	2.5
Number of operations (self-reported)	0.8	1.2	4.3	1.9	-0.8	-0.7	-0.3	0.1	2.1	1.7	1.5	-1.0	0.0	0.0	-0.4	-0.2	1.6	0.0
Supplements: Calcium	0.8	0.9	2.6	1.0	1.1	-1.5	0.5	1.6	1.6	0.2	0.9	-0.0	0.8	1.4	0.2	0.2	0.7	0.1
Intelligence (Savage-Jansen 2018)	0.7	2.3	8.1	-2.8	-0.2	-1.8	-0.7	1.1	-0.4	-1.3	-1.2	0.7	-1.4	2.2	1.9	1.7	-1.4	1.4
Alzheimer’s Disease (in mother)	0.7	0.8	2.4	-0.3	0.6	0.7	1.1	-0.2	-0.5	-1.2	-0.2	1.6	1.4	1.0	1.2	1.0	0.3	0.7
Relative age of first facial hair	0.7	1.3	5.2	-1.8	-1.2	0.6	-0.6	-1.4	-0.4	-2.3	-1.3	1.6	0.6	-1.4	0.5	0.4	-0.7	0.0
Hayfever, allergic rhinitis or eczema	0.7	1.5	5.5	-0.3	-1.1	-1.0	-2.3	-2.3	-1.4	-0.8	-1.0	0.2	-0.8	-1.2	-0.4	-0.6	-1.6	-0.7
Supplements: Glucosamine	0.7	0.9	3.2	0.6	0.8	-1.5	-1.3	0.7	0.6	1.7	0.1	-1.8	-1.0	-0.2	-0.5	-0.4	-0.1	-0.0
Trunk fat mass	0.7	2.9	8.1	-1.6	0.6	2.7	0.1	-2.9	-0.3	-0.2	0.9	1.7	-0.3	-1.3	2.3	2.5	0.8	2.7
Impedance of arm (right)	0.7	3.3	8.9	-3.0	-0.1	-2.3	-1.3	2.1	-1.9	-1.4	-2.7	-0.2	-2.2	1.8	0.1	-0.1	-2.8	-0.5
Trunk fat-free mass	0.7	3.8	7.4	0.2	1.0	2.6	2.3	-1.2	1.8	-1.4	1.7	2.7	2.7	-0.8	2.3	2.2	2.3	2.1
Falls in the last year	0.7	1.0	3.9	-0.4	-1.2	1.0	-0.7	-1.7	-1.1	-0.2	-0.4	-0.5	-1.2	-2.0	-0.4	-0.4	-0.5	-0.7
Hair/balding pattern: Pattern 3	0.7	1.0	2.8	0.5	0.4	1.2	-0.4	-0.1	-0.1	0.4	-0.4	-1.4	-1.2	-1.4	-1.4	-1.5	-0.9	-1.7
Noisy workplace	0.7	0.9	3.9	-0.2	0.5	0.7	-0.6	-1.2	-0.2	1.3	-0.6	-1.5	-1.5	-2.0	-0.4	-0.4	-0.6	-0.3
Impedance of arm (left)	0.7	3.2	8.9	-3.0	0.5	-2.5	-1.3	2.1	-1.8	-1.3	-2.3	-0.2	-2.2	2.1	0.2	0.0	-2.6	-0.3
Birth weight of first child	0.7	1.2	4.3	-1.0	0.5	0.3	-1.4	-2.1	-0.9	-1.2	-1.6	1.2	1.0	-0.7	0.8	0.6	-1.1	0.6
Blood clot in the leg (DVT)	0.7	0.9	6.3	-0.1	-2.5	-1.0	-0.5	0.2	-1.3	-0.6	-0.8	-0.8	-1.0	-0.4	-0.3	-0.4	-0.3	-0.9
Chronic bronchitis/emphysema (mother)	0.7	0.8	5.6	1.0	0.2	-2.4	-0.8	0.3	0.2	1.0	0.5	-1.1	-0.5	-1.2	-0.6	-0.6	0.1	-0.5
Wheeze or whistling in the chest in last year	0.7	1.3	5.6	0.1	0.0	0.9	-0.2	-2.4	0.8	-0.1	0.1	0.9	1.1	-2.3	1.2	1.3	1.1	1.1
Age at first live birth	0.7	1.3	4.4	-0.7	1.0	0.1	1.0	1.0	-0.0	-1.8	-0.4	1.8	1.8	2.1	1.0	0.8	-0.2	0.3
Eye problems/disorders: None of the above	0.7	0.8	6.7	-0.6	1.1	-0.1	0.5	2.6	-0.1	0.4	0.8	-0.2	-0.4	0.6	0.7	0.7	0.4	0.9
Migraine (self-reported)	0.7	0.8	4.7	0.7	0.8	-2.2	0.2	1.0	-0.2	-0.0	0.6	-0.7	-0.7	-0.4	-0.9	-1.1	-0.5	-1.3
Medication: Seretide 50 evohaler	0.7	0.8	2.7	1.1	-0.1	1.4	0.4	-0.6	1.1	1.6	1.1	-0.8	0.4	-0.7	-0.1	0.1	1.1	0.8
Leg pain on walking	0.7	0.8	4.2	1.6	-0.4	-0.6	-1.4	-1.1	-0.3	0.6	0.6	-0.5	0.3	-2.0	-0.4	-0.4	0.8	-0.3
Ever had bowel cancer screening	0.7	0.8	2.3	1.1	-1.5	0.8	-0.6	-0.9	-0.6	0.9	0.7	-1.2	-0.3	-1.4	-0.8	-0.8	0.3	-0.7
Commuting to job workplace: Walk	0.7	0.8	4.5	-0.3	-1.3	-0.6	-0.1	-0.6	-0.2	-2.1	-1.0	1.4	1.1	0.5	0.4	0.0	-0.4	-0.5
Breast cancer (self-reported)	0.7	0.8	3.5	1.2	1.0	-1.0	-0.6	1.2	0.5	-0.5	1.3	0.7	0.7	1.9	0.3	0.2	0.9	-0.0
Smoking status: Current	0.7	1.1	4.4	2.1	0.7	0.4	0.7	1.7	1.4	1.0	0.8	-0.5	0.9	0.8	-0.8	-0.7	1.3	-0.7
Hearing aid user	0.7	0.8	2.7	0.3	0.0	1.6	1.0	0.0	1.6	0.7	0.7	0.1	1.2	0.4	0.5	0.7	1.2	0.8
Arm fat-free mass (left)	0.7	3.6	8.4	0.5	1.2	2.9	1.9	-1.7	1.5	-0.4	2.2	2.1	2.1	-1.1	2.1	2.2	2.5	2.3
Deep venous thrombosis (DVT) (self-reported)	0.7	0.9	6.3	-0.2	-2.5	-1.0	-0.8	0.0	-1.4	-0.7	-0.9	-0.6	-1.1	-0.1	-0.2	-0.4	-0.4	-0.9
Heart disease (siblings)	0.7	0.8	3.2	0.8	0.0	1.8	0.6	-0.7	-0.2	1.5	0.4	-1.5	-0.4	-1.5	-0.4	-0.2	0.8	0.0
Impedance of whole body	0.7	3.7	10.6	-2.6	-0.2	-2.6	-1.9	1.5	-2.4	-0.5	-2.4	-1.4	-3.2	1.1	-0.7	-0.8	-2.9	-1.1
Arm predicted mass (left)	0.7	3.5	8.1	0.3	1.2	2.8	1.9	-1.8	1.4	-0.6	2.0	2.2	2.1	-0.9	2.2	2.2	2.3	2.3
Ulcerative Colitis (UC)	0.6	1.2	4.6	-2.2	-0.5	0.8	-0.4	-0.4	-0.8	-1.3	-0.3	1.1	0.2	0.6	1.8	1.7	-0.2	1.4
Blood Platelet Count	0.6	6.9	15.5	-1.6	-2.8	-1.8	-3.9	-2.2	-2.5	-2.6	-2.9	-0.8	-3.1	-2.8	-1.9	-2.2	-3.5	-3.2
Allergy or Eczema	0.6	1.5	6.4	-0.7	-1.5	-0.7	-2.2	-2.5	-1.2	-0.5	-1.4	0.1	-0.9	-0.9	-0.3	-0.4	-1.6	-0.4
Other serious medical condition/disability diagnosed by doctor	0.6	0.7	1.9	0.1	-0.8	-0.9	-0.4	0.8	-1.2	-0.7	-0.6	-0.2	-1.0	-0.7	-0.9	-1.0	-1.1	-1.4
Trunk fat percentage	0.6	2.3	8.4	-1.9	0.4	2.2	-0.6	-2.9	-0.8	0.2	0.5	0.9	-1.2	-1.1	1.8	2.1	0.3	2.4
Current tobacco smoking	0.6	0.9	3.8	1.9	0.6	0.2	0.4	1.6	1.4	0.8	0.5	-0.4	0.8	0.8	-0.8	-0.8	1.0	-0.8
Bilateral oophorectomy (both ovaries removed)	0.6	0.7	4.0	0.6	-0.4	-1.0	-2.0	-0.8	-0.6	-0.3	-1.3	-0.4	0.2	0.5	-0.6	-0.7	-0.9	-0.8
Body mass index (BMI)	0.6	2.5	8.1	0.6	0.2	2.8	0.6	-2.6	0.8	1.5	2.1	0.7	0.5	-2.1	1.0	1.4	1.8	2.0
Alcohol usually taken with meals	0.6	0.9	2.8	-1.5	-0.4	-1.1	-1.5	-0.7	0.0	-1.3	-1.7	1.0	-0.5	0.3	0.1	0.0	-1.2	0.0
Hearing difficulty/problems with background noise	0.6	1.0	4.1	-0.7	-1.7	-0.2	-0.4	-1.0	1.7	1.0	-0.7	-0.9	-0.8	-2.0	-0.1	-0.0	-0.4	0.5
Weight	0.6	3.1	8.6	-0.4	0.8	2.9	1.1	-2.2	0.6	-0.2	1.8	2.0	1.1	-1.5	2.2	2.4	1.8	2.6
Serious illness, injury or assault of a close relative in last 2 years	0.6	0.7	3.8	0.5	-0.3	-0.6	1.1	2.0	1.5	0.2	1.0	-0.4	-0.0	0.9	-0.4	-0.3	0.7	-0.3
Trunk predicted mass	0.6	3.7	7.1	0.1	1.0	2.6	2.3	-1.2	1.8	-1.4	1.6	2.7	2.6	-0.8	2.2	2.2	2.2	2.0
Mouth/teeth dental problems: Bleeding gums	0.6	0.8	3.3	-0.9	-0.3	-1.8	-0.7	0.9	-0.7	-0.8	-1.0	-0.2	-1.3	0.2	-0.4	-0.5	-1.5	-0.7
Arm fat-free mass (right)	0.6	3.2	7.2	0.4	0.8	2.7	1.6	-2.2	1.2	-0.6	2.0	2.1	2.0	-1.3	1.9	2.0	2.2	2.0
Exposure to tobacco smoke outside home	0.6	0.8	2.3	0.1	-0.1	-0.5	-0.0	1.4	-0.4	0.7	-0.2	-1.1	-1.0	0.3	-1.5	-1.4	-1.1	-1.3
Worry too long after embarrassment	0.6	0.9	4.2	-0.3	-1.4	-2.0	0.4	0.8	0.0	-1.4	-1.2	0.6	0.8	0.2	-0.3	-0.6	-1.1	-1.0
Number of children fathered	0.6	0.7	2.6	-1.3	0.1	0.5	-0.7	-1.5	-0.8	0.0	0.2	-0.3	-1.6	-1.2	0.1	0.1	-0.8	0.3
Reason for reducing amount of alcohol drunk: Health precaution	0.6	0.8	3.0	0.5	1.7	-0.2	-0.1	0.4	-0.2	-1.6	0.8	1.4	1.2	1.0	0.2	-0.0	-0.0	-0.5
Whole body fat mass	0.6	2.3	6.8	-1.0	0.4	2.6	0.2	-2.6	-0.1	0.3	1.3	1.2	-0.3	-1.4	1.8	2.1	1.1	2.4
Arm predicted mass (right)	0.6	3.1	6.9	0.5	1.0	2.6	1.8	-1.7	1.2	-0.6	2.0	2.0	2.0	-1.1	1.9	1.9	2.3	2.0
Had major operations	0.6	0.7	4.8	1.3	-2.2	0.0	0.4	-0.1	0.3	0.6	0.9	-0.6	0.5	-0.5	-0.4	-0.4	1.1	-0.3
Smoking status: Previous	0.6	0.9	3.0	-1.2	-1.0	1.7	1.1	-0.5	0.4	-0.5	-0.0	0.8	-0.1	0.1	1.3	1.3	0.4	1.4
Medication for cholesterol	0.6	1.0	3.8	-1.3	-0.6	-0.4	1.0	0.3	0.2	-1.8	-1.9	1.6	0.4	0.8	0.2	0.0	-0.9	-0.3
Back pain experienced in last month	0.6	0.8	2.4	1.4	-1.4	-0.6	-0.1	1.0	0.3	1.6	0.3	-1.2	-0.6	-0.7	-1.0	-0.9	0.4	-0.6
Medication: Aspirin	0.6	0.8	2.2	0.7	-1.1	0.2	-1.4	-1.3	0.2	0.6	0.1	-1.5	-0.7	-1.1	-0.9	-0.9	-0.1	-0.7
Supplements: Fish oil (including cod liver oil)	0.6	0.8	2.2	-0.1	1.0	0.1	0.2	0.3	0.5	0.3	1.2	-0.1	0.7	-0.5	1.4	1.5	1.3	1.5
Leg fat percentage (left)	0.6	2.1	7.5	-0.4	-1.1	1.5	-1.4	-2.7	-0.9	1.8	0.7	-0.9	-2.2	-2.7	-0.3	0.0	-0.1	0.6
Basal cell carcinoma (self-reported)	0.6	0.7	4.6	-0.4	0.6	-1.8	-2.1	-0.5	-0.2	0.1	-0.9	-0.4	-0.4	0.1	0.0	-0.0	-1.0	0.1
Pack years of smoking	0.6	0.8	4.2	-0.1	-0.5	0.3	1.2	0.6	2.1	0.7	-0.4	0.3	1.2	0.9	0.6	0.8	0.8	1.1
Depression (Nagel 2018)	0.5	0.8	2.6	1.1	-1.6	1.1	0.2	-0.5	1.4	0.9	-0.0	-0.5	0.9	-1.3	-0.3	-0.1	0.8	0.1
Mean Putamen Volume	0.5	0.5	2.4	0.0	-0.6	0.9	-0.8	0.2	-1.6	-1.1	-0.7	0.3	-0.0	-0.5	-0.3	-0.5	-0.5	-1.0
Systolic Blood Pressure	0.5	2.6	15.0	0.4	0.5	-0.0	1.7	2.6	1.9	1.3	0.8	-0.4	1.6	3.9	1.0	1.1	1.2	1.6
Average weekly spirits intake	0.5	0.6	6.1	0.1	-2.5	0.5	-0.3	-0.6	0.1	0.2	-1.2	-0.5	0.1	-0.1	-0.5	-0.5	-0.2	-0.3
Vitamin and mineral supplements	0.5	0.7	2.7	-0.7	-0.1	1.6	0.8	-0.4	0.4	-0.7	-0.3	1.3	1.3	0.7	0.8	0.8	0.2	0.8
Pack years adult smoking proportion	0.5	0.8	5.0	-0.1	-0.5	0.2	1.0	0.5	2.2	0.7	-0.7	0.3	1.0	0.7	0.5	0.7	0.7	1.0
Multivitamins +/- minerals	0.5	0.6	1.4	0.9	0.7	-1.2	-0.8	1.1	0.1	0.7	0.2	-1.0	-1.1	-0.1	-0.7	-0.8	-0.1	-0.8
Number of live births	0.5	0.7	2.1	0.6	-1.4	-0.7	0.4	-0.0	-0.1	1.4	1.1	-0.7	0.5	-0.1	0.5	0.6	1.1	0.9
Prospective memory result	0.5	0.6	1.8	-0.9	1.0	0.5	0.1	0.7	-1.2	-1.1	-0.0	1.3	-0.0	-0.1	0.9	0.8	-0.1	0.5
Arm fat mass (right)	0.5	2.2	7.3	-0.4	0.7	2.7	0.7	-2.1	0.3	0.8	1.7	1.2	0.2	-1.0	1.6	2.0	1.4	2.5
Hair/balding pattern: Pattern 4	0.5	1.3	5.5	2.3	-1.2	-0.5	0.3	0.1	0.4	2.3	1.4	-1.3	0.3	-0.3	-0.7	-0.5	1.5	0.0
Body fat percentage	0.5	1.8	7.5	-1.2	-0.1	2.0	-0.7	-2.7	-0.7	0.9	0.8	0.4	-1.4	-1.6	1.1	1.4	0.4	1.9
Leg fat percentage (right)	0.5	1.9	6.7	-0.0	-1.1	1.4	-1.3	-2.4	-0.5	2.0	0.8	-1.2	-2.1	-2.6	-0.6	-0.3	0.1	0.4
Comparative body size at age 10	0.5	1.4	2.6	-1.1	-1.6	-0.5	-1.6	-1.2	-1.5	-0.9	-1.5	-0.3	-1.0	-1.6	-0.6	-0.7	-1.5	-0.7
Number of full brothers	0.5	0.6	2.9	-0.3	-0.2	0.6	1.6	1.7	1.1	0.0	-0.0	-0.0	-0.5	0.7	-0.6	-0.5	-0.1	-0.3
Loneliness, isolation	0.5	0.7	3.7	-0.5	-1.9	0.9	0.0	-0.9	0.1	-0.6	-1.3	0.0	0.8	-0.6	-0.8	-0.8	-0.6	-0.7
Eye problems/disorders: Cataract	0.5	0.6	6.5	-0.1	-0.6	0.3	-0.0	-2.6	0.6	-0.4	-1.0	0.2	0.2	-0.2	-0.1	-0.2	-0.1	-0.4
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.5	1.0	4.3	-1.5	0.1	0.3	-0.2	-1.4	0.3	-0.2	-0.3	0.8	0.5	0.5	1.4	1.6	0.0	2.1
Arm fat mass (left)	0.5	2.2	6.6	-0.9	0.8	2.6	0.4	-2.3	0.2	0.7	1.4	1.1	-0.2	-1.2	1.7	2.0	1.1	2.5
Tinnitus: Yes, now most or all of the time	0.5	0.6	2.8	-0.8	-0.3	-0.2	-0.8	-0.5	-0.9	-1.7	-1.0	0.6	-0.4	0.2	-0.2	-0.4	-1.1	-0.8
Medication: Blood pressure	0.5	1.0	5.6	1.3	0.4	-0.2	-0.5	0.6	0.2	1.7	2.4	-1.1	0.2	0.3	-0.0	0.3	1.4	0.7
Medication: Bendroflumethiazide	0.5	0.8	2.9	1.0	0.7	-0.1	-1.2	-0.0	1.1	1.7	1.3	-1.1	0.5	-1.0	-0.4	-0.1	0.9	0.5
Medication: Atorvastatin	0.5	0.7	2.5	0.0	-0.9	0.5	-0.9	-1.0	-0.8	-0.4	-0.6	-0.2	-0.6	-1.6	-0.8	-0.8	-0.6	-1.2
Ever smoked	0.5	0.9	3.0	-0.9	-0.6	1.1	0.7	0.5	0.5	-1.7	-0.9	1.4	0.9	1.1	1.1	0.9	0.0	0.6
Myopia	0.5	0.8	3.0	-1.0	-0.8	0.7	-0.7	-1.0	-0.5	-1.7	-1.4	0.7	-0.8	-0.3	0.0	-0.2	-1.1	-0.7
Heart attack/myocardial infarction (self-reported)	0.5	0.7	2.9	1.7	-0.5	-0.5	-0.2	-0.8	1.3	1.2	0.7	-0.8	-0.0	-1.0	-0.6	-0.5	0.8	-0.3
Leg fat mass (left)	0.5	1.8	6.4	-0.4	0.0	2.5	-0.0	-2.5	-0.3	1.0	1.4	0.5	-0.6	-2.0	0.9	1.2	0.9	1.7
Depressed Affect (Nagel 2018)	0.4	0.9	6.0	0.7	-2.4	1.1	0.4	-0.3	1.1	-0.4	-0.3	-0.1	1.3	-1.0	-0.8	-0.7	0.6	-0.7
Schizophrenia vs Biploar Disorder	0.4	0.6	1.9	-0.1	-0.4	-0.5	-1.2	-0.4	-0.6	-0.7	-0.5	-0.3	-0.5	-0.4	-0.9	-1.0	-1.0	-1.4
Alzheimer’s Disease (including proxy)	0.4	0.6	1.2	0.1	1.0	0.9	0.9	-1.1	0.6	0.2	0.2	0.7	1.1	1.0	0.7	0.9	0.8	0.8
Crohns Disease (2017)	0.4	1.0	3.0	0.1	1.5	0.6	1.7	1.2	0.8	-0.6	1.3	0.9	1.0	0.3	0.7	0.8	1.0	0.8
Blood Eosinophil Count	0.4	3.0	7.9	-1.6	-0.1	0.6	-2.7	-1.9	-2.1	-2.1	-2.1	0.9	-1.4	-1.3	-1.0	-1.3	-2.8	-1.7
Blood Red Count	0.4	4.3	9.1	1.2	2.4	2.4	2.8	1.0	3.0	1.7	1.0	0.1	3.0	2.6	1.4	1.6	2.4	2.1
Heel T-Score	0.4	2.8	8.6	0.2	0.7	-1.8	-1.8	-0.0	-2.3	0.2	-0.1	-2.0	-2.4	-2.9	-1.7	-1.8	-1.4	-2.0
Smoking Status	0.4	0.9	2.8	0.9	-0.2	1.0	1.7	1.4	1.5	0.7	0.7	0.1	0.8	0.8	0.1	0.2	1.3	0.4
Neuroticism	0.4	0.9	4.4	0.5	-1.8	-2.1	0.7	0.9	0.6	-0.6	-0.0	-0.0	0.7	0.7	-0.8	-0.8	-0.1	-1.0
Tanning	0.4	4.5	12.0	-3.2	0.3	2.4	0.6	-1.8	0.7	-1.9	-0.5	2.5	1.5	-0.1	3.4	3.5	0.8	3.3
Medication for hormone replacement therapy	0.4	0.4	1.1	0.7	0.4	1.0	0.4	-0.5	0.7	-0.0	0.9	0.5	0.7	-1.0	0.6	0.5	0.7	0.4
Relative age voice broke	0.4	0.6	2.0	-1.4	-0.0	0.1	-1.2	-0.7	-0.6	-1.2	-1.2	0.5	0.1	-0.4	0.0	-0.0	-1.2	-0.2
Stomach or abdominal pain in last month	0.4	0.5	1.9	0.8	-0.1	-0.9	0.5	1.4	0.4	1.2	0.7	-0.4	-0.2	-0.4	-0.3	-0.3	0.7	0.2
Chronic bronchitis/emphysema (father)	0.4	0.4	1.4	-0.3	-0.3	0.7	-0.3	-1.2	-0.8	-0.0	-0.3	-0.9	-0.8	-0.9	-0.5	-0.6	-0.6	-0.6
Waist circumference	0.4	1.5	7.9	-0.3	-0.6	2.5	-0.2	-2.8	0.2	0.2	0.6	0.9	0.1	-1.4	1.0	1.2	0.7	1.4
Past tobacco smoking	0.4	0.8	2.8	0.9	1.1	-1.7	-1.3	-0.1	-0.5	0.9	0.2	-0.8	-0.2	-0.5	-1.0	-1.0	-0.4	-0.8
Heart attack	0.4	0.5	2.0	1.4	-0.5	-0.6	-0.2	-0.8	1.0	1.0	0.7	-0.7	-0.1	-0.8	-0.3	-0.2	0.7	-0.1
Arm fat percentage (right)	0.4	1.5	5.0	-0.7	0.3	2.1	0.1	-1.9	-0.0	0.9	1.2	0.9	-0.4	-0.7	1.4	1.7	0.9	2.2
Time employed in main current job	0.4	0.4	3.2	0.0	-0.6	0.0	-0.5	-0.4	-0.9	-0.5	0.1	-0.3	-0.6	-1.8	-0.4	-0.4	-0.3	-0.6
Forced expiratory volume in 1-second (FEV1), Best measure	0.4	1.2	3.4	-0.9	1.7	0.4	1.8	1.5	0.6	0.5	1.0	0.5	-0.0	0.7	1.1	1.3	0.4	1.8
Standing height	0.4	3.8	13.0	-2.2	1.7	0.6	1.4	0.6	-0.3	-3.6	-0.3	3.2	1.6	1.2	3.0	2.6	0.3	1.7
Glaucoma (self-reported)	0.4	0.4	1.9	0.2	0.4	1.4	-0.3	-0.1	-0.2	0.1	-0.3	-0.4	-0.1	-0.5	-0.9	-1.0	-1.0	-0.9
Seen a psychiatrist for nerves, anxiety, tension or depression	0.4	0.5	2.0	-1.4	-0.4	1.1	0.2	-0.4	1.0	-0.2	-1.0	0.2	-0.3	0.0	0.7	0.7	-0.4	0.8
Leg fat mass (right)	0.4	1.6	6.2	-0.2	-0.1	2.3	-0.1	-2.5	-0.0	1.1	1.3	0.3	-0.6	-2.2	0.7	1.0	1.0	1.6
Illnesses of father: Heart disease	0.4	0.5	1.7	-0.6	-0.4	-1.3	-0.3	1.3	-0.5	-0.8	-0.7	-0.4	-0.6	-0.8	-0.0	-0.2	-0.6	-0.7
Arm fat percentage (left)	0.4	1.5	4.8	-0.9	0.4	2.0	0.0	-1.8	-0.1	0.9	1.3	0.8	-0.7	-0.7	1.3	1.6	0.8	2.2
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.4	0.5	1.8	0.3	-1.0	-0.9	-1.2	-1.4	-0.2	-0.2	-0.1	-0.1	-0.4	-1.0	-0.6	-0.6	-0.2	-0.5
Illnesses of father: None of the above (group 1)	0.4	0.4	1.5	-0.5	-0.5	-0.2	-1.2	-1.2	-1.2	-0.6	-0.7	0.3	-0.6	-0.0	-0.1	-0.2	-0.7	-0.2
Miserableness	0.4	0.7	3.8	0.5	-1.9	0.8	0.8	0.1	1.4	0.3	0.1	-0.1	0.6	-1.4	-0.5	-0.3	0.7	-0.1
High cholesterol (Self-reported)	0.4	0.7	2.7	-0.6	-0.8	-0.4	-1.6	-1.2	0.2	0.8	-0.2	-0.9	-1.2	-1.0	-0.4	-0.2	-0.7	0.1
Ever had prostate specific antigen (PSA) test	0.4	0.4	2.2	-0.8	0.1	0.1	-0.6	-0.7	-0.2	0.7	0.2	-0.5	-1.5	0.6	0.4	0.5	0.4	0.6
Irritable Bowel Disease (IBD)	0.3	0.7	1.9	-1.2	0.4	0.4	0.6	0.3	-0.0	-0.9	0.6	0.9	0.5	0.4	1.3	1.4	0.4	1.3
Breast Cancer	0.3	0.7	2.0	-0.8	1.4	-0.9	-0.0	0.6	-0.1	0.1	1.4	0.5	-0.6	-1.0	1.0	1.0	0.3	1.1
Coronary Artery Disease (CAD)	0.3	0.3	1.4	0.0	0.6	-0.3	-0.2	0.9	-0.3	-0.8	0.2	1.2	0.6	0.4	0.5	0.4	0.0	0.3
Crohns Disease (2012)	0.3	0.5	1.9	-0.5	0.7	1.0	1.4	0.0	-0.2	0.0	0.9	0.5	0.3	0.2	0.6	0.7	0.6	0.8
Fasting Glucose	0.3	0.4	1.8	-0.8	-0.4	1.3	0.4	-0.3	-0.5	0.4	-0.5	-0.5	-0.2	-0.1	-0.7	-0.6	-0.8	-0.5
Blood White Count	0.3	2.1	4.7	0.4	0.2	1.5	1.6	-2.0	1.7	2.0	1.0	-0.6	0.9	0.7	1.2	1.5	2.2	2.0
Waist Hip Ratio (WHR)	0.3	1.4	8.2	-0.2	-1.4	0.8	-1.7	-2.9	-0.1	-0.5	-1.6	-0.7	-0.7	-0.5	-0.6	-0.7	-0.8	-1.1
Hypothyroidism (self reported)	0.3	0.8	4.9	-1.3	0.2	-0.5	0.4	0.1	-0.5	-2.2	-0.5	1.4	-0.5	-0.4	0.2	-0.1	-1.1	-0.7
Age when periods started (menarche)	0.3	0.6	1.9	0.1	0.4	-1.2	-0.3	1.4	0.5	-1.2	-0.4	1.2	0.7	1.2	0.5	0.3	-0.2	-0.1
Serious illness, injury or assault to yourself	0.3	0.4	1.0	0.2	-0.5	-0.5	0.7	0.2	-0.3	-0.5	-1.0	0.1	-0.6	0.9	-0.6	-0.7	-0.8	-0.8
Sitting height	0.3	1.9	4.5	-0.8	1.7	2.0	2.1	0.5	0.5	-1.5	0.0	2.0	1.6	1.1	1.6	1.4	0.5	1.2
Hair/balding pattern: Pattern 2	0.3	0.4	1.4	-0.3	-1.2	-1.0	-0.1	0.6	-0.9	-0.6	0.1	0.4	0.5	1.0	0.5	0.4	0.2	0.3
Had other major operations	0.3	0.3	1.3	0.4	1.1	-0.6	-0.8	0.6	0.8	-0.3	0.3	0.3	-0.3	0.2	-0.6	-0.6	-0.3	-0.7
Hip circumference	0.3	1.4	3.9	-0.8	0.3	1.6	0.2	-1.6	-0.2	-0.8	1.0	2.0	0.5	-0.9	1.7	1.7	0.5	1.8
Alcohol intake versus 10 years previously	0.3	0.5	2.1	-0.6	-0.9	1.4	0.0	-0.1	-0.2	-0.7	-1.1	-0.2	-0.7	-0.5	-0.5	-0.6	-0.8	-0.9
Asthma	0.3	0.6	4.1	0.6	-0.4	-0.5	0.7	0.1	-0.1	0.6	0.6	-0.9	-0.5	-2.0	-0.8	-0.7	0.3	-0.6
Medication: Cholesterol lowering	0.3	0.5	2.7	0.6	-0.6	0.8	-0.1	-1.6	0.5	0.8	0.4	-0.1	-0.0	-0.7	0.2	0.4	0.8	0.6
Lung cancer (father)	0.3	0.4	4.0	-0.0	0.2	0.9	-0.3	-2.0	-0.3	-0.5	-0.7	0.1	0.5	0.0	0.2	0.1	0.1	-0.0
Breastfed as a baby	0.3	0.3	1.9	0.1	0.9	-1.4	-0.4	-0.3	0.3	0.1	0.4	-0.2	-0.2	1.1	0.4	0.3	0.3	0.2
Peak expiratory flow (PEF)	0.3	0.6	1.9	0.5	0.7	1.3	0.9	0.1	-0.1	1.4	1.3	-0.6	-1.2	-0.9	-0.3	-0.1	0.5	0.4
Medication for cholesterol, blood pressure or diabetes	0.3	0.6	2.2	-0.8	0.7	-1.1	0.3	1.0	-0.3	-1.5	-0.5	1.0	0.4	0.8	0.2	-0.0	-0.7	-0.4
Hypothyroidism/myxoedema (self-reported)	0.3	0.6	4.5	-0.3	-0.2	-1.0	0.2	0.4	-0.1	-2.1	0.3	1.4	0.4	0.3	0.4	0.1	-0.3	-0.4
Mouth/teeth dental problems: Loose teeth	0.3	0.4	2.0	-0.1	-0.6	-0.3	0.8	-0.9	1.4	0.3	0.5	0.1	0.6	-0.5	0.4	0.5	0.6	0.6
Emphysema/chronic bronchitis	0.3	0.3	1.9	0.4	-1.4	-0.7	-0.0	-0.9	0.5	0.2	-0.3	-0.0	0.7	0.6	-0.2	-0.2	0.4	0.1
Family relationship satisfaction	0.3	0.4	1.5	0.5	0.4	0.4	0.2	0.2	1.2	0.9	0.6	-0.3	0.4	-0.7	0.2	0.4	0.9	0.8
Supplements: Vitamin C	0.3	0.4	1.2	0.5	-0.1	-0.5	-0.5	-0.7	0.3	0.4	-0.7	-0.8	-0.1	-1.1	-0.9	-0.8	-0.2	-0.5
Forced expiratory volume in 1-second (FEV1), predicted	0.3	0.6	2.4	-1.6	1.0	0.6	1.0	-0.0	0.4	-1.3	-1.1	0.4	-0.1	-0.2	0.2	0.1	-1.0	-0.2
Ever had stillbirth, spontaneous miscarriage or termination	0.3	0.4	1.4	0.5	0.9	0.3	-0.3	-0.1	-0.3	1.2	0.5	-1.2	-0.4	-0.8	-0.4	-0.2	0.2	-0.0
Mineral and other dietary supplements	0.3	0.4	1.9	0.2	-0.7	1.4	0.6	-0.4	-0.2	-0.6	-0.2	1.0	0.4	1.1	-0.1	-0.2	-0.2	-0.2
Alcohol drinker status: Never	0.3	0.4	2.2	0.2	-1.0	-1.5	1.0	1.0	0.1	-0.2	0.2	0.6	0.4	0.4	0.3	0.2	0.3	0.2
Irritability	0.3	0.6	1.5	0.6	0.1	0.5	1.1	-0.1	0.7	1.1	0.8	-1.2	-0.9	-0.4	-0.9	-0.7	0.3	-0.6
Fractured/broken bones in last 5 years	0.3	0.4	1.3	-0.1	-0.4	-0.9	-1.2	-1.0	-0.7	0.8	-0.1	-0.7	-0.5	-0.8	-0.5	-0.4	-0.4	-0.0
Cholesterol lowering medication	0.3	0.4	1.4	0.3	-0.4	1.2	-1.0	-0.5	0.2	0.9	0.8	-0.8	-0.2	-0.5	-0.0	0.1	0.4	0.4
Neuroticism (Nagel 2018)	0.2	0.5	1.7	-0.8	-1.2	-0.3	0.7	0.3	0.2	-1.3	-1.1	0.3	0.9	0.8	-0.2	-0.2	-0.6	-0.5
Lupus	0.2	0.3	1.5	-0.2	0.4	-0.9	-1.2	-1.1	-0.3	-0.1	-0.4	-0.6	0.3	-0.1	-0.3	-0.4	-0.5	-0.3
Triglycerides	0.2	0.4	1.1	0.0	-1.0	0.8	0.3	-0.3	0.4	-0.9	0.3	1.0	1.1	-0.5	0.5	0.5	0.4	0.4
Height	0.2	3.3	14.1	-2.0	0.1	0.4	1.4	0.1	0.7	-3.8	-1.0	3.0	1.7	1.5	2.6	2.2	0.4	1.1
Lung FVC	0.2	0.8	2.4	0.3	-1.1	-1.3	-0.4	1.5	-0.2	1.5	-0.3	-1.0	-0.6	0.5	-1.2	-1.0	-0.8	-0.1
Sensitivity / hurt feelings	0.2	0.3	1.6	-0.4	-0.7	0.1	0.6	-0.5	0.1	-0.1	-1.3	0.0	0.2	-0.4	-0.3	-0.3	-0.8	-0.1
Heel bone mineral density (BMD) T-score, automated (left)	0.2	0.4	1.5	-0.4	1.0	0.2	0.5	-0.3	-1.0	-0.9	0.2	0.0	-0.5	-1.2	0.3	0.1	-0.0	-0.4
Frequency of tenseness / restlessness in last 2 weeks	0.2	0.4	2.2	0.0	-0.4	1.0	0.7	-0.1	1.5	0.1	-0.6	-0.3	0.0	-0.6	-0.5	-0.5	-0.0	-0.4
Forced vital capacity (FVC)	0.2	0.6	3.2	-0.4	-0.1	-1.0	1.3	1.8	-0.5	-0.5	0.5	0.7	-0.1	1.1	0.5	0.5	0.0	0.6
Hayfever/allergic rhinitis (self-reported)	0.2	0.3	1.3	0.1	-0.5	-1.1	-1.0	-0.8	-0.8	-0.3	0.2	0.3	0.1	-0.9	-0.1	-0.2	-0.2	-0.0
Neuroticism score	0.2	0.5	2.5	0.4	-1.0	-0.7	1.6	0.7	1.0	-0.1	-0.1	0.1	0.7	-0.1	-0.6	-0.6	0.1	-0.5
Worrier / anxious feelings	0.2	0.4	1.4	-0.1	-0.4	0.1	0.9	-1.2	0.3	1.0	-0.3	-1.1	-0.0	-0.6	-0.4	-0.2	0.0	-0.0
Forced expiratory volume in 1-second (FEV1)	0.2	0.8	2.6	-0.8	0.7	-0.2	1.6	1.3	0.2	0.3	0.8	0.8	-0.3	0.9	0.9	1.1	0.3	1.6
Seen doctor (GP) for nerves, anxiety, tension or depression	0.2	0.4	3.4	-0.1	-1.8	-0.2	0.3	-0.8	-0.3	0.3	-0.5	-0.7	0.1	-0.5	0.0	0.0	0.1	0.0
Medication: Aspirin	0.2	0.3	1.3	0.1	-0.6	-0.2	-1.1	-1.1	0.0	0.1	-0.0	-0.9	-0.5	-0.7	-0.4	-0.3	-0.1	-0.3
Asthma (self-reported)	0.2	0.4	3.5	0.7	-0.1	-0.2	0.9	-0.0	0.6	0.3	0.7	-0.2	0.3	-1.9	-0.2	-0.1	0.8	-0.0
Alzheimer’s Disease (in father)	0.1	0.1	0.5	-0.2	0.0	0.0	0.1	-0.7	0.7	0.4	-0.1	0.0	-0.2	0.7	0.1	0.2	0.0	0.3
Respiratory disease	0.1	0.3	2.4	0.0	0.4	0.0	-0.1	-0.8	-0.8	-0.2	0.4	0.1	0.1	-1.6	0.3	0.3	0.2	0.1
Maternal smoking around birth	0.1	0.2	0.6	0.3	-0.0	0.6	-0.0	-0.5	0.2	0.0	0.5	-0.2	-0.5	-0.8	-0.3	-0.4	0.0	-0.6
Heel bone mineral density (BMD) T-score, automated (right)	0.1	0.3	1.4	-0.5	0.5	0.6	0.4	-0.8	-0.7	-0.7	-0.0	-0.1	-0.5	-1.2	0.2	0.1	0.1	-0.3
Forced vital capacity (FVC), Best measure	0.1	0.5	3.7	-0.0	0.5	-0.4	1.2	1.9	-0.1	0.2	0.9	-0.0	-0.1	0.6	0.3	0.3	0.2	0.5
Comparative height size at age 10	0.1	0.4	2.0	0.1	-0.3	0.5	0.0	-1.3	-0.3	-0.3	0.5	0.2	0.3	-1.4	0.7	0.7	0.8	0.5
Prostate Cancer	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Hair Pigment	0.0	1.4	6.3	0.7	2.2	0.8	0.4	0.4	1.4	1.1	0.9	0.7	0.9	2.5	0.5	0.6	1.4	0.8

Hub : Genes

MCM9

Models

Trait associations