Best TWAS P=2.83e-15 · Best GWAS P=2.88e-15 conditioned to 1
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Heart Left Ventricle | LINC00961 | 0.13 | 0.02 | lasso | 4 | 0.03 | 9.8e-03 | -7.9 | 7.2 | 7.6e-13 | -0.89 | 0 | 0.96 | FALSE |
2 | GTEx | Nerve Tibial | LINC00961 | 0.18 | 0.17 | lasso | 5 | 0.17 | 2.4e-12 | -7.9 | 7.9 | 2.8e-15 | -0.99 | 0 | 1.00 | TRUE |
3 | GTEx | Stomach | LINC00961 | 0.22 | 0.10 | lasso | 3 | 0.05 | 2.1e-03 | -7.9 | 7.7 | 1.7e-14 | -0.98 | 0 | 0.98 | FALSE |
4 | GTEx | Thyroid | LINC00961 | 0.22 | 0.07 | enet | 20 | 0.11 | 7.5e-09 | -7.9 | 6.1 | 1.4e-09 | -0.69 | 0 | 1.00 | FALSE |
5 | The Cancer Genome Atlas | Prostate Adenocarcinoma | LOC158376 | 0.09 | 0.06 | lasso | 3 | 0.08 | 1.9e-08 | -7.9 | 6.8 | 9.0e-12 | -0.89 | 0 | 1.00 | FALSE |
6 | The Cancer Genome Atlas | Thyroid Carcinoma | LOC158376 | 0.13 | 0.09 | lasso | 5 | 0.08 | 4.5e-08 | -7.9 | 7.9 | 4.0e-15 | -0.99 | 0 | 1.00 | FALSE |