TWAS hub - LINC00961

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Heart Left Ventricle	0.130	0.0495	3.3e-03	0.021	NA	0.021	NA	0.030	2.6e-02	NA	2.5e-02	NA	9.9e-03
2	GTEx	Nerve Tibial	0.181	0.0616	1.1e-03	0.170	NA	0.171	NA	0.174	4.1e-12	NA	3.8e-12	NA	2.4e-12
3	GTEx	Stomach	0.220	0.0820	3.8e-03	0.098	NA	0.045	NA	0.050	2.0e-05	NA	3.2e-03	NA	2.1e-03
4	GTEx	Thyroid	0.216	0.0540	9.5e-07	0.071	NA	0.111	NA	0.105	3.9e-06	NA	7.5e-09	NA	1.9e-08
5	ROSMAP	Brain Pre-frontal Cortex	0.037	0.0185	1.6e-02	0.014	0.011	0.018	0.012	0.020	5.1e-03	0.014	1.9e-03	0.0084	1.1e-03

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5
Pulse rate	15.5	26.2	35.1	4.6	5.9	5.8	5.6	3.2
Pulse rate, automated reading	13.9	44.8	62.4	7.2	7.9	7.7	6.1	3.9
Medication: Seretide 50 evohaler	10.6	12.2	23.7	4.0	3.0	3.3	4.9	1.1
Supplements: Calcium	7.7	8.4	11.1	-3.3	-3.2	-3.3	-2.2	-2.3
Pulse wave reflection index	7.4	9.1	13.1	-3.1	-3.6	-3.3	-3.1	-1.2
Ulcerative Colitis	5.8	8.4	11.8	-2.9	-3.1	-3.3	-3.4	-1.3
Average weekly fortified wine intake	5.5	6.5	8.4	-2.9	-2.7	-2.7	-2.6	-1.7
Had other major operations	4.8	5.9	8.1	-2.4	-2.8	-2.6	-1.9	-2.2
Chronic bronchitis/emphysema (father)	3.6	4.3	5.2	2.1	2.2	2.2	1.4	2.3
Alzheimer’s Disease (in mother)	3.3	3.9	6.1	1.2	1.9	1.9	2.2	2.5
High blood pressure (siblings)	3.2	4.6	7.4	-2.1	-2.2	-2.1	-2.7	-1.3
Back pain experienced in last month	3.2	4.6	7.7	-2.8	-1.9	-1.9	-2.6	-1.1
Ever had hysterectomy (womb removed)	3.0	3.4	4.4	1.3	2.1	1.9	2.1	1.6
Eye problems/disorders: Cataract	3.0	3.5	4.9	-1.6	-1.7	-1.6	-2.1	-2.2
Fasting Glucose	2.7	3.2	5.4	-1.8	-1.7	-1.5	-2.3	-1.5
Taking other prescription medications	2.6	4.0	5.2	1.8	2.1	2.0	1.7	2.3
Hand grip strength (right)	2.2	5.8	8.6	-2.7	-2.9	-2.6	-0.5	-2.5
Alcohol usually taken with meals	2.2	3.5	6.2	-1.9	-1.8	-1.9	-2.5	-0.9
Pulse wave Arterial Stiffness index	2.2	2.6	4.2	-1.9	-2.1	-2.0	-1.0	0.3
Loud music exposure frequency	2.1	2.3	3.5	-1.9	-1.3	-1.2	-1.5	-1.7
Ever had bowel cancer screening	2.1	2.5	7.8	0.5	0.2	-0.0	2.8	2.1
Qualifications: nursing, teaching	2.1	3.3	4.4	2.0	2.1	1.9	0.7	2.0
Bilateral oophorectomy (both ovaries removed)	2.0	2.3	3.4	1.7	1.6	1.4	1.8	0.5
Reason for reducing amount of alcohol drunk: Health precaution	2.0	2.4	5.1	0.6	1.6	1.5	1.1	2.2
Worry (Nagel 2018)	1.9	3.9	5.6	-2.3	-2.2	-2.4	-1.8	-0.9
Reproduciblity of spirometry measurement using ERS/ATS criteria	1.9	2.3	4.2	1.4	1.5	2.0	1.5	1.0
Mother’s age at death	1.9	2.4	6.5	1.4	1.2	1.4	0.3	2.5
Ulcerative Colitis (UC)	1.8	3.3	5.1	-2.3	-1.6	-2.0	-2.0	0.8
Serious illness, injury or assault to yourself	1.8	2.2	4.3	-1.4	-1.4	-1.4	-2.1	-0.9
Asthma	1.8	3.5	4.3	1.6	1.7	2.0	1.9	2.1
Birth weight	1.8	4.0	9.4	2.0	1.5	1.7	3.1	1.0
Pulse wave peak to peak time	1.8	2.2	3.6	1.7	1.9	1.8	1.1	-0.2
Asthma (self-reported)	1.8	3.6	4.6	1.5	1.7	2.0	2.0	2.1
Relative age of first facial hair	1.7	3.5	6.1	1.5	1.6	2.0	2.5	1.6
Falls in the last year	1.7	2.3	5.5	-2.4	-1.2	-1.1	-1.5	-0.9
Medication: Amlodipine	1.7	2.4	9.1	-0.6	-1.0	-0.9	-3.0	-0.8
Commuting to job workplace: Walk	1.7	1.9	3.3	1.8	1.4	1.6	1.2	0.2
Hearing aid user	1.6	1.8	2.7	-1.3	-1.5	-1.4	-1.6	-0.6
Average weekly spirits intake	1.5	1.8	2.4	-1.5	-1.2	-1.3	-1.4	-1.3
Fed-up feelings	1.5	2.8	5.8	-2.4	-1.4	-1.5	-1.5	-1.3
Fluid intelligence score	1.5	3.0	5.5	2.3	2.0	2.1	1.0	-0.7
Leg pain on walking	1.5	1.9	3.8	-1.4	-1.5	-1.1	-2.0	-0.1
Guilty feelings	1.5	2.3	3.8	-1.7	-1.5	-1.3	-0.8	-1.9
Alcohol intake versus 10 years previously	1.4	2.1	2.9	1.0	1.7	1.7	1.4	1.3
Medication: Metformin	1.3	1.8	3.1	-1.8	-1.0	-1.4	-0.9	-1.5
Financial difficulties in last 2 years	1.3	1.8	2.9	-1.1	-1.0	-1.3	-1.4	-1.7
Neck or shoulder pain in last month	1.3	1.8	4.0	0.8	1.3	1.0	2.0	1.3
Comparative height size at age 10	1.3	7.2	13.7	-2.6	-3.3	-3.7	-0.2	-2.1
Commuting to job workplace: Public transport	1.3	1.5	4.8	2.2	0.9	1.1	0.7	0.5
Fractured/broken bones in last 5 years	1.3	1.7	3.2	-1.3	-1.7	-1.8	-0.7	-0.6
Heart attack/myocardial infarction (self-reported)	1.3	1.7	4.0	1.4	0.8	0.9	2.0	0.9
Heel bone mineral density (BMD) T-score, automated (left)	1.2	2.7	4.2	2.1	1.3	2.0	1.8	-0.2
Medication: Ramipril	1.2	1.5	3.2	-0.7	-1.4	-1.2	-0.7	-1.8
Mean time to correctly identify matches	1.2	2.3	4.6	2.2	1.6	1.7	0.8	0.9
Average weekly red wine intake	1.2	1.8	3.4	-0.9	-1.2	-0.8	-1.6	-1.9
Breast cancer (self-reported)	1.2	1.4	2.1	1.5	1.0	0.8	1.4	1.1
Forced expiratory volume in 1-second (FEV1), predicted percentage	1.2	2.5	3.7	1.2	1.7	1.8	1.0	1.9
Tinnitus: Yes, now most or all of the time	1.2	1.4	2.5	-1.2	-1.2	-1.2	-1.6	-0.5
Medication: Atorvastatin	1.2	1.4	4.7	1.1	0.4	0.1	2.2	1.1
Illnesses of father: High blood pressure	1.2	1.5	4.6	-0.9	-0.7	-0.7	-2.1	-1.0
Pack years of smoking	1.2	1.8	4.6	2.2	1.3	1.1	1.1	0.4
HbA1C	1.1	1.2	1.9	-1.3	-1.4	-1.2	0.8	-0.7
Systolic Blood Pressure	1.1	5.4	7.7	-2.6	-2.7	-2.8	-2.3	-0.3
Medication: Co-codamol	1.1	1.3	4.1	0.0	-0.7	-0.8	-1.1	-2.0
Diabetes (mother)	1.1	1.4	3.1	0.8	1.8	1.4	0.7	1.0
Qualifications: None of the above	1.1	2.4	4.8	1.2	1.3	1.5	1.3	2.2
Length of working week for main job	1.1	1.2	2.2	-1.5	-0.6	-0.9	-1.3	-0.9
Medication: Ventolin 100micrograms inhaler	1.1	1.4	2.2	-1.5	-1.3	-1.4	-0.9	0.6
Chronic bronchitis/emphysema (mother)	1.1	1.3	2.0	-0.9	-1.2	-1.4	-1.3	-0.6
Medication: Allopurinol	1.1	1.4	3.5	-0.8	-1.5	-1.9	-0.2	-0.8
Ever taken oral contraceptive pill	1.1	1.3	2.0	1.0	1.3	1.4	1.3	-0.3
Pack years adult smoking proportion	1.0	1.5	4.0	2.0	1.2	1.0	1.0	-0.3
Heart attack	1.0	1.3	3.2	1.2	0.6	0.7	1.8	1.0
Arm fat percentage (right)	1.0	3.8	7.6	0.9	2.4	2.2	0.5	2.8
Prospective memory result	1.0	1.2	2.2	-0.6	-1.5	-1.4	-1.0	-0.7
Qualifications: O levels/GCSEs or equivalent	1.0	1.6	2.2	-1.4	-1.4	-1.5	-1.3	-0.7
Eye problems/disorders: None of the above	1.0	1.2	1.8	0.9	1.0	1.0	1.2	1.3
Number of full sisters	1.0	1.2	3.5	0.9	1.0	0.7	1.9	0.3
Illnesses of siblings: Diabetes	1.0	1.2	4.2	0.5	0.4	0.2	1.2	2.0
Arm fat percentage (left)	1.0	3.9	7.5	0.9	2.4	2.2	0.9	2.7
Ever smoked	1.0	1.7	3.7	-0.5	-1.4	-0.8	-1.9	-1.4
Unable to work because of sickness or disability	1.0	1.3	1.6	-1.2	-1.2	-1.3	-0.5	-1.3
Type 2 Diabetes (T2D) (2012)	0.9	1.0	1.9	0.6	1.0	1.1	0.7	1.4
Waist Hip Ratio (WHR)	0.9	4.1	6.4	-2.1	-2.5	-2.5	-0.1	-1.8
Ever used hormone-replacement therapy (HRT)	0.9	1.2	2.2	1.0	1.3	1.5	0.8	0.4
Current tobacco smoking	0.9	1.5	4.7	-0.6	-1.0	-0.8	-0.7	-2.2
Forced expiratory volume in 1-second (FEV1), predicted	0.9	1.8	4.9	-2.2	-1.3	-1.4	-0.4	-0.2
Osteoporosis (self-reported)	0.9	1.1	4.1	-0.0	0.8	0.7	0.3	2.0
Hearing difficulty/problems: Yes	0.8	1.2	2.6	-0.9	-0.0	0.2	-1.6	1.6
Trunk fat percentage	0.8	3.1	6.5	0.4	1.9	1.7	1.6	2.5
Diverticular disease/diverticulitis (self-reported)	0.8	0.9	1.3	-1.1	-1.0	-0.8	-0.9	-0.8
Number of children fathered	0.8	0.9	1.7	0.8	0.8	0.8	0.8	1.3
Age at first live birth	0.8	1.5	2.8	-0.8	-1.7	-1.4	-0.6	-1.3
Ever had stillbirth, spontaneous miscarriage or termination	0.8	0.9	1.4	0.8	1.2	0.8	0.8	-1.0
Smoking status: Current	0.8	1.3	4.1	-0.6	-1.0	-0.7	-0.9	-2.0
Medication: Bendroflumethiazide	0.8	1.2	1.9	-1.1	-1.4	-1.4	-1.0	0.1
Mean Putamen Volume	0.7	0.8	1.7	-1.3	-1.0	-1.1	-0.4	-0.1
Rheumatoid Arthritis	0.7	0.9	1.2	1.0	0.8	1.1	0.9	1.1
BMI	0.7	3.8	6.2	1.3	2.5	2.4	-0.2	2.3
Smoking Status	0.7	1.7	3.2	-0.5	-1.2	-0.9	-1.7	-1.8
Frequency of depressed mood in last 2 weeks	0.7	1.0	2.0	0.3	1.4	1.4	0.3	1.1
Medication for hormone replacement therapy	0.7	0.8	3.2	-0.3	-0.6	-0.3	-0.5	-1.8
Relative age voice broke	0.7	1.1	1.8	0.5	1.1	1.2	1.0	1.3
Nervous feelings	0.7	1.4	2.0	-1.4	-1.2	-1.3	-1.1	-0.5
Hearing difficulty/problems with background noise	0.7	1.1	3.7	-0.6	0.6	0.8	0.3	1.9
Medication: Cholesterol lowering	0.7	1.2	1.8	1.3	0.7	0.9	1.3	-1.1
Seen doctor (GP) for nerves, anxiety, tension or depression	0.7	1.0	4.4	-0.5	0.5	0.4	0.1	2.1
Peak expiratory flow (PEF)	0.7	1.5	2.6	-1.5	-1.6	-1.6	0.0	-0.5
Body fat percentage	0.7	2.8	5.8	0.5	1.9	1.8	1.0	2.4
Seen a psychiatrist for nerves, anxiety, tension or depression	0.7	1.0	1.4	0.2	1.2	1.1	0.9	1.1
Suffer from ‘nerves’	0.7	1.0	1.8	-0.7	-1.2	-1.3	-0.9	-0.8
Supplements: Vitamin C	0.7	0.8	3.6	0.1	-0.2	0.1	1.9	-0.6
Number of self-reported non-cancer illnesses	0.7	1.2	4.5	0.6	0.5	0.7	0.4	2.1
Wears glasses or contact lenses	0.7	0.8	1.4	-0.6	-1.0	-1.1	-1.2	0.3
Medication: Blood pressure	0.7	1.2	4.0	0.7	1.0	0.9	-0.2	2.0
Medication: Paracetamol	0.7	1.1	3.1	0.9	1.0	0.9	1.8	0.2
Diastolic blood pressure, automated reading	0.7	2.2	4.8	1.0	2.0	2.2	-0.3	1.1
Pain experienced in last month	0.7	1.2	2.2	1.2	0.6	0.8	1.2	1.5
Heart disease (siblings)	0.7	0.9	1.7	1.0	1.1	1.3	0.6	0.0
Bipolar Disorder (2018)	0.6	1.0	1.5	-0.9	-1.1	-1.1	-0.2	-1.2
Breast Cancer	0.6	1.4	2.7	1.2	1.6	1.6	0.4	0.2
Tanning	0.6	7.0	9.6	-3.0	-3.0	-3.1	-1.9	-2.0
Hand grip strength (left)	0.6	1.5	2.0	-1.2	-1.4	-1.0	1.0	-1.4
Tinnitus: Yes, but not now, but have in the past	0.6	0.6	1.4	-0.4	0.9	1.2	0.9	0.2
Heel bone mineral density (BMD) T-score, automated (right)	0.6	1.4	2.6	1.6	0.9	1.5	1.2	0.3
Pain all over the body in last month	0.6	0.6	2.6	0.4	0.1	0.5	-0.0	-1.6
Hip circumference	0.6	2.6	8.9	0.5	1.4	1.1	0.8	3.0
Mouth/teeth dental problems: Bleeding gums	0.6	0.8	2.1	0.8	1.1	1.4	0.3	0.4
Number of full brothers	0.6	0.7	1.0	0.9	0.8	1.0	1.0	0.2
Alcohol drinker status: Never	0.6	0.7	1.6	-1.3	-0.5	-0.4	-0.6	-1.1
Bipolar Disorder or Schizophrenia	0.5	1.2	2.7	-0.7	-1.1	-1.7	0.9	-0.8
Alzheimer’s Disease (including proxy)	0.5	0.8	1.8	0.1	0.5	0.6	1.2	1.3
Irritable Bowel Disease (IBD)	0.5	1.2	1.7	-1.3	-0.8	-1.3	-1.1	0.9
Reaction Time	0.5	1.0	2.8	1.7	0.9	0.8	0.8	0.4
Bipolar Disorder (2011)	0.5	0.5	1.7	-0.3	0.0	-1.3	-0.5	0.7
Blood Red Count	0.5	4.6	7.4	1.6	2.2	2.1	1.9	2.7
Number of treatments/medications taken	0.5	0.9	2.0	0.7	1.1	1.4	0.9	0.3
Other serious medical condition/disability diagnosed by doctor	0.5	0.6	1.8	-0.7	-0.6	-0.3	-1.3	0.7
Angina	0.5	0.6	1.5	-0.8	-0.5	-0.8	1.2	0.5
Illnesses of siblings	0.5	0.7	1.3	1.1	0.6	0.6	0.8	-1.0
Father’s age at death	0.5	0.7	1.3	-1.1	-0.8	-0.6	-0.9	0.6
Happiness	0.5	0.6	2.1	-0.6	-0.2	-0.5	-0.1	-1.5
Serious illness, injury or assault of a close relative in last 2 years	0.5	0.6	1.6	0.2	1.3	1.1	0.1	0.3
Impedance of arm (left)	0.5	2.4	5.6	0.6	1.2	1.1	2.4	1.8
Trunk predicted mass	0.5	2.6	4.2	-1.9	-1.9	-2.1	-1.1	-0.6
Exposure to tobacco smoke at home	0.5	0.6	2.0	-0.2	-0.6	-0.5	-0.5	-1.4
Gout (self-reported)	0.5	0.7	1.9	-0.5	-0.9	-1.4	0.8	-0.1
Angina (self-reported)	0.5	0.7	1.2	-0.9	-0.7	-0.9	1.1	0.4
Heart disease (mother)	0.5	0.7	3.0	-0.1	-0.1	-0.3	-1.7	-0.3
Illness, injury, bereavement, stress in last 2 years	0.5	0.7	2.2	1.5	0.0	0.3	0.8	-0.6
Arm fat mass (left)	0.5	1.8	4.9	0.2	1.5	1.3	0.6	2.2
Pain type(s) experienced in last month: Hip pain	0.5	0.7	2.2	-0.3	-0.7	-0.6	-1.5	-0.5
Average weekly beer plus cider intake	0.5	0.8	2.0	1.0	0.5	0.5	0.7	-1.4
Age started oral contraceptive pill	0.5	0.6	1.3	0.1	0.9	1.1	0.7	0.8
Myopia	0.5	0.8	2.6	0.6	0.8	0.4	1.6	0.4
Neuroticism (Nagel 2018)	0.4	1.0	2.5	-1.6	-0.9	-0.9	-0.9	-0.1
Schizophrenia (2018)	0.4	0.7	1.8	-0.1	-0.6	-1.2	1.3	0.0
Neuroticism (2016)	0.4	0.6	1.1	-0.4	1.0	1.0	0.8	-0.2
Blood White Count	0.4	2.8	12.0	-0.9	-0.5	-0.8	-3.5	0.6
Respiratory disease	0.4	0.9	1.1	0.9	0.8	1.1	0.9	0.9
Supplements: Zinc	0.4	0.5	1.4	-0.7	-0.4	-0.2	-0.3	-1.2
Age when periods started (menarche)	0.4	0.9	1.7	0.6	1.0	1.0	0.6	1.3
High blood pressure	0.4	1.2	4.6	-0.5	-0.7	-0.7	-2.1	0.1
Stomach or abdominal pain in last month	0.4	0.5	1.0	0.3	0.6	0.6	-0.7	1.0
Trunk fat mass	0.4	1.6	4.3	-0.2	1.2	1.0	1.1	2.1
Hair/balding pattern: Pattern 2	0.4	0.5	1.4	-0.5	-0.7	-0.5	-1.2	-0.6
Had menopause	0.4	0.5	1.1	-0.1	-0.8	-0.6	-1.1	-0.4
Ever unenthusiastic/disinterested for a whole week	0.4	0.4	1.7	0.2	0.2	0.6	-0.2	-1.3
Impedance of arm (right)	0.4	1.8	3.3	0.5	1.2	1.1	1.8	1.8
Trunk fat-free mass	0.4	2.6	4.2	-1.9	-1.9	-2.0	-1.1	-0.7
Lung cancer (father)	0.4	0.4	1.3	-0.1	0.6	0.4	1.1	0.4
Standing height	0.4	4.5	8.5	-2.5	-2.5	-2.9	1.1	-0.0
Blood clot in the leg (DVT)	0.4	0.5	0.9	-0.9	-0.4	-0.9	0.2	0.9
Headache pain in last month	0.4	0.6	2.7	-0.5	-0.2	-0.4	-1.6	0.2
Medication for cholesterol, blood pressure or diabetes	0.4	0.7	1.7	-1.3	-0.8	-1.0	-0.2	0.4
Glaucoma (self-reported)	0.4	0.5	1.5	0.1	0.4	0.4	-0.6	1.2
Leg fat percentage (right)	0.4	1.3	2.7	0.2	1.3	1.4	-0.2	1.7
Arm fat-free mass (right)	0.4	2.1	3.5	-1.7	-1.7	-1.9	-0.7	-0.7
Whole body fat mass	0.4	1.6	4.3	0.0	1.3	1.1	0.8	2.1
Qualifications: NVQ or HND or HNC or equivalent	0.4	0.4	0.6	-0.7	-0.6	-0.8	-0.8	-0.3
Commuting to job workplace: Car/motor vehicle	0.4	0.4	1.8	-1.3	-0.1	-0.2	-0.1	-0.5
Medication: Aspirin	0.4	0.6	1.7	0.2	0.8	0.6	1.3	0.5
Knee pain experienced in last month	0.4	0.6	1.0	0.8	0.9	1.0	0.1	0.7
Mood swings	0.4	0.7	1.4	0.2	1.0	0.9	0.6	1.2
Friendships satisfaction	0.4	0.5	2.0	-0.6	-0.0	0.1	-0.4	-1.4
Illnesses of father: None of the above (group 1)	0.4	0.5	2.4	-0.6	0.2	0.0	1.5	-0.1
Eye problems/disorders: Glaucoma	0.4	0.5	0.8	0.3	0.8	0.9	-0.2	0.8
Supplements: Fish oil (including cod liver oil)	0.4	0.6	1.9	0.2	0.7	0.6	1.4	-0.2
Leg fat percentage (left)	0.4	1.4	2.7	0.1	1.4	1.5	-0.2	1.6
Arm fat-free mass (left)	0.4	2.3	3.6	-1.9	-1.8	-1.9	-0.9	-0.6
Prostate Cancer	0.3	0.5	1.0	-0.0	-1.0	-0.9	-0.7	-0.4
Body Mass Index (BMI) (2010)	0.3	0.4	0.6	0.6	0.7	0.8	-0.7	0.0
Schizophrenia (2014)	0.3	0.6	1.3	0.1	-0.5	-1.1	1.0	-0.6
Triglycerides	0.3	0.5	1.1	-0.7	-0.8	-1.1	-0.1	-0.4
Height	0.3	6.4	12.7	-2.1	-3.0	-3.6	2.3	-0.3
Hypothyroidism (self reported)	0.3	0.8	1.0	1.0	0.8	0.8	0.7	1.0
Lung FVC	0.3	1.8	2.9	1.2	1.6	1.7	0.9	1.1
Frequency of unenthusiasm / disinterest in last 2 weeks	0.3	0.4	1.0	0.3	1.0	0.8	0.6	0.1
Qualifications: CSEs or equivalent	0.3	0.4	1.0	-1.0	-0.2	-0.8	0.7	0.2
Medication: Atenolol	0.3	0.4	1.1	-0.1	-0.7	-0.4	-0.3	1.0
Medication: Levothyroxine sodium	0.3	0.5	1.3	0.4	0.6	0.3	0.7	1.2
Number of incorrect matches in round	0.3	0.5	1.6	-0.4	0.1	-0.1	-1.3	-0.8
Medication: Simvastatin	0.3	0.4	1.6	0.1	0.2	0.4	-0.5	-1.3
Frequency of tiredness / lethargy in last 2 weeks	0.3	0.5	0.9	0.5	0.9	0.7	0.3	-0.9
Hair/balding pattern: Pattern 3	0.3	0.5	0.8	-0.5	-0.7	-0.8	0.6	-0.9
Number of live births	0.3	0.4	0.9	1.0	0.6	0.3	0.6	0.7
Noisy workplace	0.3	0.3	1.4	-0.0	0.4	0.2	0.2	1.2
Arm fat mass (right)	0.3	1.3	3.6	0.2	1.3	1.1	0.3	1.9
Ever highly irritable/argumentative for 2 days	0.3	0.4	1.7	-0.2	0.3	0.3	0.2	-1.3
Exposure to tobacco smoke outside home	0.3	0.5	1.7	0.1	-0.2	0.1	-0.7	-1.3
Wheeze or whistling in the chest in last year	0.3	0.6	2.2	-0.6	0.2	0.3	0.1	1.5
Health satisfaction	0.3	0.3	0.7	-0.7	-0.3	-0.1	-0.7	-0.9
Mouth/teeth dental problems: Loose teeth	0.3	0.3	0.7	-0.6	-0.1	-0.2	0.8	0.8
Emphysema/chronic bronchitis	0.3	0.4	1.6	-0.2	-0.4	-0.3	-1.3	0.1
Medication: Blood pressure	0.3	0.5	2.1	0.5	0.1	0.1	-1.4	0.3
Arm predicted mass (right)	0.3	1.7	3.0	-1.7	-1.5	-1.7	-0.4	-0.5
Age at last live birth	0.3	0.5	1.7	0.5	0.1	0.1	1.3	-0.5
Hypertension (Self-reported)	0.3	0.7	2.8	-0.1	-0.1	-0.2	-1.7	0.8
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.3	0.3	0.6	-0.7	-0.8	-0.6	-0.1	-0.2
Illnesses of father: Heart disease	0.3	0.4	0.7	0.2	-0.9	-0.8	-0.5	-0.6
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.3	0.4	0.6	-0.2	-0.7	-0.8	0.4	-0.7
Osteoarthritis (self-reported)	0.3	0.4	0.9	-0.6	-1.0	-0.8	0.5	-0.0
Medication: Gliclazide	0.3	0.3	0.5	-0.7	-0.2	-0.7	0.3	-0.6
Average weekly champagne plus white wine intake	0.3	0.4	1.0	1.0	0.3	0.1	0.7	-0.6
Medication: Lisinopril	0.3	0.4	1.2	0.7	0.5	0.4	-1.1	0.3
Irritability	0.3	0.6	1.1	-1.0	-0.8	-0.8	0.2	-0.7
Risk taking	0.3	0.5	1.1	0.1	0.5	0.3	1.0	1.0
Commuting to job workplace: Cycle	0.3	0.3	1.0	-0.4	-0.4	-0.5	-0.2	1.0
Deep venous thrombosis (DVT) (self-reported)	0.3	0.3	0.7	-0.7	-0.1	-0.6	0.3	0.8
Arm predicted mass (left)	0.3	1.7	2.8	-1.7	-1.5	-1.6	-0.9	-0.5
Depressed Affect (Nagel 2018)	0.2	0.5	1.2	-1.1	-0.3	-0.2	-0.8	0.8
Depression (Nagel 2018)	0.2	0.3	0.7	0.1	0.8	0.8	-0.2	0.6
Intelligence (Savage-Jansen 2018)	0.2	0.8	1.2	1.1	1.0	1.0	0.7	-0.1
Schizophrenia vs Biploar Disorder	0.2	0.2	0.7	0.5	0.3	0.1	-0.2	-0.8
Alzheimer’s Disease (in father)	0.2	0.2	0.6	0.1	0.3	-0.1	-0.4	0.8
Ovarian Cancer	0.2	0.2	1.0	0.2	-0.1	-0.3	0.1	-1.0
Coronary Artery Disease (CAD)	0.2	0.3	0.7	0.9	0.1	-0.4	-0.6	0.2
Blood Eosinophil Count	0.2	1.4	3.5	-1.7	-0.7	-0.5	-1.9	0.1
Blood Platelet Count	0.2	2.8	5.2	1.1	2.3	1.5	-0.5	2.3
Cardiovascular Disease	0.2	0.6	2.3	-0.5	-0.5	-0.4	-1.5	-0.2
Type 2 Diabetes (T2D) (2018)	0.2	0.3	0.8	0.3	0.9	0.6	-0.5	-0.1
Lung FEV1/FVC ratio	0.2	0.8	1.2	-0.9	-0.9	-1.1	-0.9	-0.5
Sensitivity / hurt feelings	0.2	0.4	1.3	-0.5	-0.2	-0.4	0.2	1.1
Eye problems/disorders: Diabetes related eye disease	0.2	0.2	0.8	-0.3	0.1	-0.4	0.9	0.3
Vitamin and mineral supplements	0.2	0.3	0.9	0.1	-0.4	-0.4	-1.0	-0.4
Severe depression (siblings)	0.2	0.2	0.6	-0.2	-0.5	-0.5	0.3	-0.8
Multivitamins +/- minerals	0.2	0.3	0.8	-0.9	-0.4	-0.5	-0.5	0.1
Body mass index (BMI)	0.2	0.9	1.9	0.3	1.2	1.1	-0.2	1.4
Waist circumference	0.2	0.7	2.5	-0.8	0.1	-0.2	0.4	1.6
Forced vital capacity (FVC)	0.2	0.6	1.0	-1.0	-0.9	-1.0	0.6	0.1
Time employed in main current job	0.2	0.2	0.5	-0.7	-0.5	-0.2	-0.5	0.2
Worrier / anxious feelings	0.2	0.4	0.7	-0.6	-0.5	-0.8	0.4	0.5
Forced expiratory volume in 1-second (FEV1)	0.2	0.7	1.3	-1.1	-0.9	-1.1	0.4	-0.2
Medication: Ibuprofen (e.g. Nurofen)	0.2	0.3	1.1	0.1	0.3	0.5	0.2	-1.0
Breastfed as a baby	0.2	0.2	0.9	-0.1	-0.1	-0.2	0.2	0.9
Tense / ‘highly strung’	0.2	0.3	0.9	0.1	0.4	0.4	0.5	1.0
Birth weight of first child	0.2	0.4	0.7	-0.5	-0.7	-0.8	0.6	-0.6
Hypothyroidism/myxoedema (self-reported)	0.2	0.4	1.8	0.4	0.2	0.1	0.1	1.4
Comparative body size at age 10	0.2	0.6	1.9	-0.4	-0.2	-0.5	-1.4	-0.9
Medication for pain relief, constipation, heartburn	0.2	0.4	0.9	0.6	0.1	0.0	-0.6	1.0
Medication: Ibuprofen	0.2	0.2	1.0	-0.2	-0.2	0.0	-0.3	-1.0
Leg fat mass (right)	0.2	0.9	2.7	-0.2	0.9	0.9	0.0	1.6
Had major operations	0.2	0.2	0.7	0.2	0.2	0.3	-0.2	0.8
Family relationship satisfaction	0.2	0.3	0.5	-0.7	-0.7	-0.6	-0.1	-0.1
Whole body fat-free mass	0.2	1.4	2.6	-1.5	-1.3	-1.6	-0.5	-0.1
Handedness (chirality/laterality): Left-handed	0.2	0.2	0.4	-0.6	-0.0	-0.1	-0.7	0.4
Loneliness, isolation	0.2	0.3	0.9	-0.5	0.5	0.5	-0.2	0.9
Long-standing illness, disability or infirmity	0.2	0.3	0.8	-0.3	-0.3	-0.4	-0.9	0.5
Mineral and other dietary supplements	0.2	0.3	0.9	0.4	-0.1	-0.0	-0.9	0.7
Medication: Aspirin	0.2	0.3	1.2	0.2	0.4	0.2	1.1	0.0
Whole body water mass	0.2	1.3	2.5	-1.5	-1.3	-1.6	-0.5	-0.1
Financial situation satisfaction	0.2	0.3	1.3	0.3	-0.0	0.2	0.2	-1.1
Basal metabolic rate	0.2	0.9	1.8	-1.4	-1.0	-1.2	-0.3	0.1
Vascular/heart problems diagnosed by doctor	0.2	0.6	2.6	0.2	0.4	0.4	1.6	-0.1
Basal cell carcinoma (self-reported)	0.2	0.3	0.7	0.5	0.4	0.6	0.2	-0.8
Leg fat mass (left)	0.2	0.9	2.6	-0.3	0.9	0.9	0.0	1.6
Crohns Disease (2017)	0.1	0.3	0.5	0.6	0.7	0.4	0.3	0.7
Major Depression (MDD)	0.1	0.1	0.1	-0.3	0.2	-0.2	-0.0	-0.4
Verbal and Numeric Reasoning (VNR)	0.1	0.3	1.3	0.3	0.3	0.3	0.2	-1.1
Age at First Birth	0.1	0.2	0.5	-0.4	-0.2	-0.1	0.3	-0.7
Crohns Disease (2012)	0.1	0.1	0.3	0.5	0.0	-0.1	-0.3	-0.5
HDL Cholesterol	0.1	0.1	0.2	-0.2	-0.4	-0.5	-0.3	-0.2
Primary Biliary Cirrhosis	0.1	0.2	0.3	0.4	0.3	0.5	0.5	-0.3
Heel T-Score	0.1	0.9	2.1	1.3	0.6	1.5	0.6	-0.0
Allergy or Eczema	0.1	0.2	0.5	-0.5	-0.1	-0.1	0.7	0.6
Neuroticism	0.1	0.2	0.5	-0.7	-0.5	-0.4	-0.5	0.2
Systolic blood pressure, automated reading	0.1	0.2	0.6	-0.6	-0.1	-0.1	-0.4	0.8
Diabetes (father)	0.1	0.1	0.2	-0.4	0.0	-0.2	-0.4	-0.2
Leg fat-free mass (left)	0.1	0.5	0.8	-0.9	-0.4	-0.9	0.2	0.6
Maternal smoking around birth	0.1	0.1	0.3	-0.1	0.6	0.1	0.5	0.2
Hayfever, allergic rhinitis or eczema	0.1	0.3	0.6	-0.8	-0.7	-0.4	-0.2	-0.1
Supplements: Glucosamine	0.1	0.1	0.2	-0.3	-0.1	0.1	-0.5	-0.4
Sitting height	0.1	1.0	2.0	-1.4	-1.0	-1.4	-0.2	-0.3
Impedance of leg (left)	0.1	0.3	0.6	-0.7	-0.7	-0.3	0.3	-0.6
Leg predicted mass (left)	0.1	0.5	0.9	-1.0	-0.5	-1.0	0.3	0.6
Past tobacco smoking	0.1	0.3	0.9	0.3	0.5	0.3	1.0	0.0
Frequency of tenseness / restlessness in last 2 weeks	0.1	0.2	0.4	-0.6	-0.3	-0.1	-0.6	-0.5
Mouth/teeth dental problems	0.1	0.1	0.3	-0.1	-0.0	-0.2	0.5	-0.3
Allergy	0.1	0.2	0.4	0.2	-0.2	-0.5	-0.4	-0.6
Diabetes (self-reported)	0.1	0.1	0.3	0.1	0.5	0.2	0.3	0.2
Hayfever/allergic rhinitis (self-reported)	0.1	0.1	0.4	-0.0	-0.6	-0.3	0.1	-0.4
Neuroticism score	0.1	0.2	0.5	-0.7	-0.4	-0.4	-0.4	0.1
Weight	0.1	0.5	1.7	-0.9	-0.1	-0.4	0.1	1.3
Qualifications: A levels/AS levels or equivalent	0.1	0.2	0.9	0.1	0.2	0.1	0.1	1.0
Mouth/teeth dental problems: Dentures	0.1	0.2	0.5	0.1	-0.3	-0.4	0.6	0.7
Depression (self-reported)	0.1	0.2	0.3	-0.5	0.5	0.4	0.3	0.4
Medication: Lansoprazole	0.1	0.1	0.3	0.5	-0.3	0.0	-0.4	0.0
Illnesses of mother	0.1	0.2	0.6	-0.3	-0.8	-0.4	0.2	0.1
Forced expiratory volume in 1-second (FEV1), Best measure	0.1	0.4	0.7	-0.8	-0.7	-0.6	0.0	-0.8
Hair/balding pattern: Pattern 4	0.1	0.4	1.0	-1.0	-0.5	-0.7	-0.2	-0.0
Medication: Paracetamol	0.1	0.2	0.5	0.0	0.3	0.2	0.7	-0.5
Worry too long after embarrassment	0.1	0.1	0.4	0.3	0.1	0.3	0.3	-0.6
Shortness of breath walking on level ground	0.1	0.1	0.1	-0.2	-0.4	-0.0	-0.3	0.3
Qualifications: College or University degree	0.1	0.2	0.4	0.1	0.6	0.5	-0.5	-0.1
Migraine (self-reported)	0.1	0.2	0.5	-0.4	0.4	-0.1	-0.1	0.7
Medication: Omeprazole	0.1	0.2	0.5	-0.2	0.4	0.3	0.1	0.7
Overall health rating	0.1	0.3	0.7	-0.9	-0.3	-0.3	-0.3	0.6
Smoking status: Previous	0.1	0.2	0.4	-0.2	-0.1	-0.1	-0.6	0.7
Leg fat-free mass (right)	0.1	0.5	1.0	-1.0	-0.5	-1.0	0.2	0.5
Diabetes diagnosed by doctor	0.1	0.2	0.3	-0.6	-0.0	-0.5	-0.5	-0.2
Mouth/teeth dental problems: Mouth ulcers	0.1	0.1	0.3	-0.3	0.2	0.5	0.5	0.2
Medication for cholesterol	0.1	0.2	0.6	-0.3	-0.3	-0.5	0.1	-0.8
Leg predicted mass (right)	0.1	0.6	1.3	-1.1	-0.7	-1.1	0.1	0.4
Miserableness	0.1	0.2	0.7	-0.4	-0.2	0.1	-0.9	0.3
High cholesterol (Self-reported)	0.1	0.1	0.4	0.2	-0.1	-0.0	0.5	-0.6
Number of operations (self-reported)	0.1	0.1	0.2	-0.4	-0.3	-0.3	-0.1	0.3
Ever had prostate specific antigen (PSA) test	0.1	0.1	0.2	-0.4	-0.4	-0.5	-0.2	0.0
Ever depressed for a whole week	0.1	0.2	0.7	-0.1	0.1	0.1	-0.2	-0.9
Medication: Omeprazole (e.g. Zanprol)	0.1	0.1	0.4	-0.6	0.1	0.1	-0.1	0.6
Alcohol drinker status: Previous	0.1	0.1	0.3	-0.3	-0.4	-0.4	-0.1	-0.6
Impedance of whole body	0.1	0.6	2.2	-0.1	0.3	0.4	1.5	0.7
LDL Cholesterol	0.0	0.0	0.1	0.3	0.0	-0.1	0.1	-0.2
Lupus	0.0	0.1	0.1	-0.4	-0.2	-0.2	-0.3	0.1
Chronotype (morning person)	0.0	0.1	0.2	0.2	0.1	-0.3	-0.5	-0.2
Hair Pigment	0.0	1.2	2.0	1.3	1.4	1.4	0.1	0.7
Impedance of leg (right)	0.0	0.2	0.3	-0.4	-0.5	-0.1	0.5	-0.4
Townsend deprivation index at recruitment	0.0	0.0	0.1	-0.1	0.1	0.2	0.4	-0.1
High blood pressure (mother)	0.0	0.0	0.1	0.0	0.2	-0.1	-0.1	-0.3
Forced vital capacity (FVC), Best measure	0.0	0.1	0.2	-0.3	-0.3	-0.2	0.5	-0.2
Alcohol intake frequency.	0.0	0.1	0.2	-0.2	0.3	0.2	-0.5	0.2
Chest pain or discomfort	0.0	0.1	0.2	-0.1	-0.3	-0.4	0.1	0.1
Cholesterol lowering medication	0.0	0.1	0.1	-0.2	-0.0	-0.2	0.3	0.2

Hub : Genes

LINC00961

Models

Trait associations