Best TWAS P=1.8e-07 · Best GWAS P=1.07e-07 conditioned to 0.0174
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Nerve Tibial | HSD17B3 | 0.14 | 0.00 | enet | 20 | 0.00 | 2.4e-01 | -5.2 | -5.2 | 1.8e-07 | 0.69 | 0.04 | 0.70 | TRUE |
| 2 | The Cancer Genome Atlas | Glioblastoma Multiforme | HABP4 | 0.08 | 0.06 | blup | 44 | 0.05 | 1.6e-02 | -5.3 | 5.2 | 2.5e-07 | -0.96 | 0.02 | 0.71 | FALSE |
| 3 | The Cancer Genome Atlas | Head and Neck Squamous Cell Carcinoma | HABP4 | 0.02 | 0.02 | blup | 44 | 0.02 | 7.1e-03 | -4.8 | -5.2 | 1.9e-07 | 0.94 | 0.03 | 0.64 | FALSE |
| 4 | The Cancer Genome Atlas | Brain Lower Grade Glioma | HABP4 | 0.05 | 0.08 | lasso | 5 | 0.08 | 6.9e-09 | -5.2 | 5.2 | 2.0e-07 | -0.98 | 0.02 | 0.98 | FALSE |
| 5 | The Cancer Genome Atlas | Thyroid Carcinoma | CDC14B | 0.05 | 0.07 | blup | 42 | 0.08 | 4.8e-08 | -4.9 | 5.2 | 1.8e-07 | -0.93 | 0.02 | 0.98 | FALSE |