[Hub]/) : Traits : Pulse rate, automated reading : ← →

chr9:122,669,622-124,303,632

Best TWAS P=9.84e-10 · Best GWAS P=1.46e-09 conditioned to 0.37

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Subcutaneous MEGF9 0.19 0.18 lasso 6 0.18 6.7e-15 -5.7 -5.4 5.9e-08 0.78 0.03 0.97 FALSE
2 GTEx Adipose Visceral Omentum MEGF9 0.10 0.08 enet 8 0.07 1.6e-04 -5.7 -5.7 1.3e-08 0.83 0.03 0.95 FALSE
3 GTEx Breast Mammary Tissue MEGF9 0.10 0.04 enet 15 0.05 9.1e-04 -5.7 -5.6 2.1e-08 0.80 0.02 0.98 FALSE
4 GTEx Heart Atrial Appendage RP11-27I1.4 0.09 0.09 lasso 5 0.06 1.1e-03 -6.0 -6.1 9.8e-10 0.94 0.01 0.96 TRUE
5 GTEx Liver PSMD5 0.30 0.22 enet 18 0.24 2.1e-07 -4.2 -5.3 9.6e-08 0.69 0.04 0.96 FALSE
6 GTEx Muscle Skeletal PSMD5 0.31 0.31 enet 20 0.34 6.0e-34 -5.0 -5.2 2.5e-07 0.59 0.38 0.62 FALSE
7 GTEx Skin Sun Exposed Lower leg PSMD5 0.04 0.04 lasso 6 0.03 3.1e-03 -5.7 -5.9 3.1e-09 0.82 0.02 0.96 FALSE
8 GTEx Skin Sun Exposed Lower leg MEGF9 0.11 0.10 lasso 5 0.12 2.7e-10 -5.5 -5.6 2.3e-08 0.81 0.03 0.97 FALSE
9 METSIM Adipose MEGF9 0.14 0.18 bslmm 372 0.19 4.7e-27 -5.6 -5.5 5.0e-08 0.79 0.03 0.97 FALSE
10 YFS Blood MEGF9 0.13 0.19 lasso 12 0.20 2.9e-64 -5.4 5.2 1.5e-07 -0.74 0.09 0.91 FALSE
11 The Cancer Genome Atlas Brain Lower Grade Glioma LOC253039 0.63 0.64 enet 11 0.66 1.6e-99 -5.0 -5.2 2.7e-07 0.61 0.00 0.99 FALSE
12 The Cancer Genome Atlas Brain Lower Grade Glioma PSMD5 0.24 0.24 enet 19 0.25 1.1e-27 -5.0 -5.3 9.2e-08 0.62 0.00 1.00 FALSE
13 The Cancer Genome Atlas Lung Adenocarcinoma MEGF9 0.02 0.03 blup 51 0.02 2.4e-03 -5.6 -5.8 8.3e-09 0.82 0.02 0.88 FALSE
14 The Cancer Genome Atlas Uterine Corpus Endometrial Carcinoma LOC253039 0.24 0.26 lasso 2 0.23 5.7e-07 -5.0 -5.2 2.5e-07 0.61 0.00 0.99 FALSE