TWAS hub - PSMD5

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.2330	0.0500	0.0e+00	0.224	0.188	0.226	0.216	0.228	8.9e-27	2.0e-22	4.6e-27	7.6e-26	2.4e-27
2	GTEx	Adrenal Gland	0.3999	0.0841	6.4e-09	0.217	NA	0.233	NA	0.038	2.6e-08	NA	7.2e-09	NA	1.7e-02
3	GTEx	Artery Tibial	0.0399	0.0230	8.0e-03	0.049	NA	0.023	NA	0.033	1.0e-04	NA	6.4e-03	NA	1.2e-03
4	GTEx	Cells Transformed fibroblasts	0.2510	0.0540	6.2e-12	0.184	NA	0.185	NA	0.161	9.1e-14	NA	7.3e-14	NA	4.2e-12
5	GTEx	Esophagus Mucosa	0.1210	0.0460	5.9e-04	0.081	NA	0.081	NA	-0.004	4.5e-06	NA	4.3e-06	NA	7.7e-01
6	GTEx	Heart Atrial Appendage	0.1410	0.0590	2.2e-03	0.017	NA	0.022	NA	-0.005	5.5e-02	NA	3.6e-02	NA	6.9e-01
7	GTEx	Liver	0.2980	0.0870	2.1e-05	0.225	NA	0.242	NA	0.136	6.4e-07	NA	2.1e-07	NA	1.3e-04
8	GTEx	Muscle Skeletal	0.3118	0.0574	0.0e+00	0.311	NA	0.336	NA	0.328	4.4e-31	NA	6.0e-34	NA	5.0e-33
9	GTEx	Pancreas	0.1220	0.0580	3.2e-03	0.124	NA	0.052	NA	0.019	7.1e-06	NA	3.0e-03	NA	5.1e-02
10	GTEx	Skin Sun Exposed Lower leg	0.0400	0.0170	1.0e-03	0.038	NA	0.018	NA	0.026	4.1e-04	NA	1.2e-02	NA	3.1e-03
11	GTEx	Thyroid	0.2220	0.0550	1.6e-10	0.185	NA	0.204	NA	0.186	3.9e-14	NA	1.6e-15	NA	3.3e-14
12	METSIM	Adipose	0.0401	0.0185	1.4e-03	0.014	0.013	0.010	0.011	0.015	3.2e-03	4.3e-03	1.2e-02	6.5e-03	2.0e-03
13	TCGA	Kidney Renal Clear Cell Carcinoma	0.1610	0.0456	0.0e+00	0.194	0.213	0.218	NA	0.222	2.3e-21	1.4e-23	3.5e-24	NA	1.3e-24
14	TCGA	Kidney Renal Papillary Cell Carcinoma	0.1360	0.0580	1.6e-06	0.132	0.130	0.131	NA	0.129	5.8e-08	6.7e-08	6.5e-08	NA	7.6e-08
15	TCGA	Brain Lower Grade Glioma	0.2383	0.0628	0.0e+00	0.237	0.241	0.246	NA	0.235	1.4e-26	4.1e-27	1.1e-27	NA	2.2e-26
16	TCGA	Prostate Adenocarcinoma	0.1264	0.0450	8.6e-10	0.099	0.096	0.108	NA	0.103	1.6e-10	2.9e-10	2.4e-11	NA	6.8e-11
17	TCGA	Testicular Germ Cell Tumors	0.2260	0.0880	4.1e-05	0.091	0.156	0.149	NA	0.105	4.0e-04	3.6e-06	6.3e-06	NA	1.5e-04
18	TCGA	Thyroid Carcinoma	0.3360	0.0820	0.0e+00	0.216	0.208	0.227	NA	0.210	9.3e-21	6.4e-20	7.5e-22	NA	3.7e-20

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17	18
Hayfever, allergic rhinitis or eczema	12.2	26.4	48.9	5.1	7.0	4.9	5.7	4.6	2.4	4.5	5.8	5.1	5.0	5.3	4.7	4.6	5.3	4.8	4.8	6.9	4.5
Hypothyroidism (self reported)	9.5	21.9	27.9	5.2	4.9	4.7	4.6	4.9	2.5	5.1	5.3	5.0	4.3	4.7	4.5	4.9	5.0	4.8	4.2	4.6	4.5
Birth weight	8.6	18.8	30.2	-3.9	-5.0	-4.5	-5.5	-4.6	-3.7	-4.4	-4.1	-3.9	-2.7	-4.4	-4.8	-5.0	-3.9	-3.4	-4.8	-4.2	-4.3
Allergy or Eczema	8.3	21.8	43.7	4.7	6.6	4.3	5.0	4.3	2.5	4.0	5.2	4.5	4.9	4.8	4.1	4.1	4.7	4.0	4.5	6.5	3.9
Rheumatoid Arthritis	7.7	10.6	19.5	3.2	4.1	3.1	3.4	2.9	1.3	2.6	3.5	3.3	2.9	3.7	3.6	3.0	4.4	3.8	3.0	2.9	2.5
Allergy	7.5	17.4	33.9	-4.1	-5.8	-3.7	-4.7	-3.7	-2.2	-3.3	-4.7	-4.3	-3.6	-4.4	-3.9	-3.7	-4.0	-3.9	-4.1	-5.8	-3.7
Hypothyroidism/myxoedema (self-reported)	6.9	13.4	17.8	4.2	3.7	3.7	3.4	3.9	2.0	4.0	4.2	3.9	3.2	3.7	3.4	3.8	3.6	3.9	3.4	3.6	3.7
Pulse rate, automated reading	6.7	21.5	35.2	-4.6	-4.7	-5.0	-4.6	-4.3	-3.7	-5.3	-5.2	-5.0	-5.9	-3.9	-4.7	-4.6	-4.4	-5.3	-3.2	-4.0	-4.3
Blood Platelet Count	6.4	74.8	92.7	-8.8	-9.1	-8.7	-9.1	-7.9	-6.9	-8.8	-9.6	-9.5	-9.6	-8.4	-9.3	-8.3	-9.1	-8.9	-7.8	-8.0	-7.3
Time employed in main current job	6.3	7.2	10.7	-2.6	-2.2	-3.3	-3.1	-2.6	-0.7	-2.6	-2.5	-3.0	-1.3	-3.1	-3.0	-2.9	-2.6	-2.6	-3.2	-2.6	-3.1
Supplements: Vitamin C	6.3	7.4	10.7	-2.4	-2.2	-3.0	-2.9	-2.1	-1.2	-2.6	-2.7	-2.9	-2.1	-3.2	-3.0	-2.5	-2.9	-3.2	-3.3	-2.9	-2.8
Osteoarthritis (self-reported)	5.9	7.6	13.3	-2.9	-3.6	-2.8	-2.6	-2.5	-2.4	-2.7	-3.0	-3.0	-3.4	-2.0	-2.4	-2.5	-3.3	-2.9	-2.5	-3.1	-1.5
Suffer from ‘nerves’	5.0	7.8	12.8	-3.1	-2.7	-2.6	-2.6	-2.6	-2.2	-3.1	-2.9	-2.8	-3.6	-2.8	-2.9	-2.5	-3.3	-3.1	-1.9	-2.4	-2.6
Hayfever/allergic rhinitis (self-reported)	4.9	6.4	9.2	2.7	2.9	2.5	2.7	2.4	1.3	2.6	2.9	2.6	2.4	2.6	2.1	2.4	2.3	2.8	2.0	3.0	2.8
Pain experienced in last month	4.7	7.8	11.4	2.7	2.4	2.7	3.0	2.7	3.0	3.2	3.2	3.4	2.9	2.3	3.1	2.9	3.3	2.9	1.7	1.4	2.5
Systolic Blood Pressure	4.2	21.1	25.5	5.0	4.2	5.0	4.7	4.8	2.1	4.6	5.0	4.8	4.5	4.6	4.8	4.9	4.9	4.5	5.0	4.7	3.8
Respiratory disease	4.2	9.4	17.7	3.2	3.4	2.7	3.3	2.9	1.8	2.8	3.4	2.9	2.7	3.1	3.0	3.0	2.8	2.9	3.7	4.2	2.8
Mouth/teeth dental problems	4.2	6.4	8.8	2.5	2.2	2.9	2.9	2.3	2.8	2.7	2.8	2.4	3.0	2.1	2.5	2.5	2.8	2.5	2.5	1.7	2.1
Average weekly fortified wine intake	4.0	4.7	8.5	2.0	1.6	2.3	2.3	2.2	1.6	2.7	2.2	1.7	2.5	2.1	2.0	2.2	1.9	2.4	2.9	2.2	1.6
Asthma (self-reported)	4.0	8.0	14.8	2.7	3.2	2.7	3.2	2.6	1.0	2.4	2.9	2.9	1.8	3.0	2.7	2.8	2.7	2.7	3.9	3.7	2.7
Medication: Atorvastatin	4.0	5.0	8.5	-2.5	-1.8	-2.3	-2.2	-2.5	-1.8	-2.8	-2.2	-2.2	-2.5	-2.0	-1.8	-2.4	-1.9	-2.2	-1.4	-2.1	-2.9
Medication: Omeprazole	3.9	4.6	14.0	-1.9	-2.3	-2.2	-2.2	-1.5	-0.7	-1.6	-2.3	-2.2	-2.6	-2.1	-2.0	-1.8	-1.6	-2.3	-2.6	-3.7	-1.7
Medication: Levothyroxine sodium	3.8	6.4	8.9	2.8	2.3	3.0	2.4	2.6	0.5	2.8	2.8	2.6	1.9	2.5	2.4	2.6	2.6	2.7	2.4	2.9	2.5
Other serious medical condition/disability diagnosed by doctor	3.7	4.8	7.0	2.3	2.2	2.2	2.6	2.6	1.4	2.5	2.4	2.2	1.1	2.3	2.4	2.6	1.6	1.9	2.4	1.4	2.4
Asthma	3.7	7.4	15.1	2.6	2.9	2.5	3.0	2.5	1.2	2.4	2.7	2.7	1.8	2.9	2.6	2.7	2.6	2.6	3.9	3.6	2.6
Osteoporosis (self-reported)	3.7	4.6	7.7	1.9	2.2	2.1	2.6	2.5	2.1	2.5	2.2	2.0	1.5	1.9	1.8	2.5	2.0	2.3	2.8	1.2	1.9
Medication: Omeprazole (e.g. Zanprol)	3.6	4.4	8.0	-1.9	-2.3	-2.2	-2.3	-1.6	-1.2	-1.7	-2.5	-2.3	-2.4	-2.4	-2.2	-1.8	-1.6	-2.1	-2.2	-2.8	-1.6
Height	3.5	66.5	92.5	9.2	6.5	8.4	7.2	8.3	9.2	9.6	8.4	8.8	8.9	7.5	7.5	8.4	8.6	9.6	6.1	4.6	8.2
Systolic blood pressure, automated reading	3.5	10.3	15.9	3.6	2.3	3.4	2.6	3.1	0.8	3.4	3.6	3.5	4.0	3.5	3.1	3.1	3.4	3.5	3.2	3.5	2.7
Severe depression (siblings)	3.5	3.9	5.6	-2.0	-2.1	-2.0	-2.2	-1.9	-1.3	-1.8	-2.2	-2.4	-1.8	-2.0	-2.2	-2.0	-1.6	-2.2	-1.9	-1.8	-2.0
Had major operations	3.5	4.1	6.4	2.1	2.3	2.1	2.5	2.0	1.7	1.9	2.5	1.9	1.4	2.0	1.9	2.1	1.9	1.9	1.7	2.0	2.0
Pulse rate	3.4	5.8	8.6	-2.5	-2.5	-2.5	-2.5	-2.2	-2.7	-2.4	-2.8	-2.6	-2.7	-2.0	-2.5	-2.4	-1.7	-2.5	-1.3	-1.9	-2.9
Reproduciblity of spirometry measurement using ERS/ATS criteria	3.3	4.0	6.0	-2.0	-2.1	-2.0	-2.3	-1.8	-1.0	-1.7	-2.2	-2.1	-1.8	-1.9	-2.0	-1.9	-2.2	-1.9	-2.4	-2.5	-1.6
Medication: Gliclazide	3.3	3.8	8.1	-1.7	-1.8	-1.9	-2.1	-1.9	-2.8	-2.4	-1.8	-1.8	-2.1	-1.8	-2.3	-2.1	-1.3	-1.5	-1.6	-1.0	-2.2
Hand grip strength (right)	3.0	8.2	13.1	3.6	2.2	2.9	2.4	2.9	2.7	3.4	3.0	3.1	3.6	2.2	2.7	2.7	3.6	3.6	2.1	1.8	1.9
Worry (Nagel 2018)	2.9	6.0	9.1	-2.8	-2.4	-2.4	-2.4	-2.3	-1.8	-2.4	-2.1	-2.4	-2.9	-2.3	-2.6	-2.2	-2.6	-3.0	-2.4	-2.4	-2.5
Age at First Birth	2.9	4.2	8.4	2.4	1.7	2.1	1.5	2.2	1.4	2.0	1.8	2.1	2.2	1.8	1.7	2.1	2.9	2.2	2.6	2.3	1.3
Birth weight of first child	2.9	5.2	7.9	-2.1	-2.8	-2.1	-2.6	-2.4	-2.2	-2.2	-2.4	-2.0	-2.1	-1.9	-2.4	-2.3	-2.3	-2.3	-2.2	-2.3	-2.2
Depression (Nagel 2018)	2.8	4.2	7.4	-2.0	-2.3	-2.1	-1.8	-1.7	-1.5	-1.9	-2.0	-2.1	-2.7	-1.4	-2.1	-1.8	-2.3	-2.5	-2.0	-2.5	-1.3
Medication: Ventolin 100micrograms inhaler	2.8	3.6	6.6	1.7	2.6	2.0	2.3	1.7	0.7	1.4	2.2	1.9	1.3	2.1	1.7	1.8	1.7	1.6	2.5	2.3	1.4
Ever had hysterectomy (womb removed)	2.7	3.0	5.6	1.4	1.9	1.6	2.3	1.3	2.1	1.0	2.0	1.8	0.5	2.1	2.4	1.7	1.0	1.8	1.6	1.5	2.2
Happiness	2.7	3.3	4.6	-2.1	-1.9	-2.0	-1.6	-1.9	-1.5	-1.5	-2.0	-1.7	-1.5	-1.8	-1.6	-1.8	-2.0	-1.9	-1.5	-2.1	-1.9
Peak expiratory flow (PEF)	2.7	6.2	8.3	2.6	2.8	2.6	2.7	1.9	1.4	2.3	2.5	2.7	2.6	2.4	2.9	2.0	2.4	2.8	2.4	2.6	2.5
Blood White Count	2.6	18.9	38.1	-4.6	-6.2	-3.8	-4.7	-3.8	-5.0	-4.0	-4.7	-4.5	-5.5	-3.7	-4.2	-3.9	-4.0	-4.3	-1.8	-3.6	-4.4
Forced expiratory volume in 1-second (FEV1), Best measure	2.6	8.1	12.4	2.5	3.5	3.3	3.4	2.5	2.7	2.9	3.0	3.0	2.4	2.4	3.4	3.0	2.5	2.9	2.5	2.6	2.6
Standing height	2.6	26.0	42.4	5.9	4.2	5.1	4.4	4.9	6.4	6.1	5.4	5.5	6.5	4.3	4.4	5.0	5.1	6.3	2.8	2.2	5.1
Medication: Amlodipine	2.6	3.6	8.1	1.9	1.4	1.7	1.7	2.0	1.7	1.8	2.2	1.9	1.3	2.0	1.5	2.0	1.3	1.9	2.4	2.8	2.0
Forced expiratory volume in 1-second (FEV1), predicted	2.6	5.3	9.0	2.2	2.2	2.5	2.6	2.3	2.9	2.4	1.8	2.1	2.1	2.5	3.0	2.5	2.5	2.1	2.2	1.0	2.0
Ever taken oral contraceptive pill	2.6	2.9	5.7	-1.6	-1.2	-1.8	-1.6	-1.3	0.2	-1.8	-1.9	-1.8	-2.1	-1.9	-1.6	-1.4	-1.5	-2.4	-1.7	-1.7	-2.0
Pulse wave peak to peak time	2.5	3.0	7.0	1.4	1.4	2.2	2.0	1.9	1.0	1.7	1.7	1.7	0.5	1.7	2.3	2.3	1.1	2.0	0.9	0.9	2.6
Seen doctor (GP) for nerves, anxiety, tension or depression	2.4	3.7	9.5	-1.9	-2.6	-1.5	-1.5	-1.6	-1.4	-2.0	-1.5	-1.7	-3.1	-1.0	-1.4	-1.6	-2.3	-1.9	-1.8	-3.1	-1.3
Neck or shoulder pain in last month	2.4	3.4	6.1	-1.9	-2.4	-1.2	-1.7	-1.5	-2.2	-1.7	-2.0	-2.2	-2.5	-1.7	-1.3	-1.4	-2.1	-2.1	-1.0	-1.7	-1.7
Leg pain on walking	2.4	3.0	7.3	-1.9	-1.2	-1.5	-1.3	-1.6	-0.2	-2.2	-1.5	-2.0	-2.7	-1.8	-2.1	-1.8	-1.2	-2.0	-1.3	-1.9	-1.9
Medication: Laxatives (e.g. Dulcolax, Senokot)	2.4	2.8	4.3	1.9	2.0	1.5	1.9	1.7	1.4	1.7	2.1	1.6	1.6	2.0	1.6	1.7	1.3	1.2	1.4	1.6	1.6
Lung cancer (father)	2.3	2.7	6.9	-1.6	-2.6	-1.6	-2.0	-1.7	-2.0	-1.6	-1.6	-1.2	-2.0	-1.5	-1.7	-1.6	-1.4	-1.2	-1.2	-1.4	-1.1
Friendships satisfaction	2.3	2.8	7.3	-1.8	-2.0	-1.5	-1.7	-1.8	-2.7	-1.7	-1.6	-1.5	-1.6	-1.5	-1.5	-1.6	-1.1	-1.5	-0.8	-1.2	-2.3
Depressed Affect (Nagel 2018)	2.2	4.7	10.4	-2.2	-2.2	-1.6	-1.9	-1.6	-1.3	-1.9	-2.0	-1.8	-3.1	-2.1	-2.1	-1.6	-2.0	-2.9	-2.5	-3.2	-1.6
Blood Eosinophil Count	2.2	17.3	23.5	4.2	4.8	4.5	4.7	4.5	3.3	4.4	4.6	4.3	3.5	3.5	3.8	4.4	4.4	3.6	4.3	4.1	3.5
Impedance of leg (right)	2.2	10.5	15.8	3.2	3.2	3.3	3.3	3.1	2.4	3.2	3.4	3.5	3.2	3.3	4.0	3.3	2.8	3.5	3.0	3.3	3.2
Maternal smoking around birth	2.2	3.2	5.0	-2.0	-1.9	-2.0	-1.5	-1.6	-0.8	-1.4	-1.9	-2.2	-1.5	-1.9	-1.9	-1.6	-2.2	-1.9	-1.2	-2.0	-1.9
Forced vital capacity (FVC), Best measure	2.2	7.9	10.9	2.6	3.1	3.3	3.3	2.7	2.8	3.1	3.0	2.9	2.6	2.3	3.2	3.0	2.5	2.9	2.1	2.1	2.7
Average weekly red wine intake	2.2	3.2	6.8	1.8	1.8	1.9	2.0	2.0	2.6	2.0	1.4	1.4	1.8	1.4	1.8	2.0	1.9	1.6	1.8	0.8	1.8
Neuroticism (Nagel 2018)	2.1	4.9	9.1	-2.2	-2.1	-2.0	-2.1	-1.7	-1.3	-1.9	-1.9	-2.0	-2.9	-2.1	-2.6	-1.7	-2.1	-3.0	-2.4	-2.9	-1.8
Relative age of first facial hair	2.1	4.3	9.9	1.6	2.8	2.4	2.5	2.0	3.1	2.3	1.8	1.8	2.0	1.5	2.1	2.3	1.4	1.9	1.9	0.8	2.0
Impedance of leg (left)	2.1	10.3	14.2	3.1	3.3	3.4	3.3	3.0	2.0	3.2	3.4	3.4	3.2	3.1	3.8	3.3	2.7	3.5	3.1	3.6	3.0
Back pain experienced in last month	2.1	3.1	5.0	-2.1	-1.2	-1.8	-1.7	-2.0	-1.4	-2.1	-1.7	-2.2	-1.7	-1.2	-1.9	-2.0	-2.2	-1.9	-1.2	-1.2	-1.7
Neuroticism (2016)	2.0	2.9	4.6	-2.1	-1.5	-1.7	-1.6	-1.6	-0.9	-1.6	-2.1	-1.8	-1.7	-1.6	-1.9	-1.5	-2.0	-2.0	-1.6	-1.9	-1.4
Medication: Metformin	2.0	2.8	6.1	-1.2	-1.7	-1.9	-1.9	-1.4	-1.7	-1.9	-1.6	-1.6	-2.5	-1.1	-2.2	-1.8	-1.2	-1.6	-1.5	-1.6	-1.5
Wears glasses or contact lenses	2.0	2.3	3.2	-1.5	-1.6	-1.6	-1.5	-1.7	-1.2	-1.7	-1.4	-1.6	-1.0	-1.3	-1.6	-1.8	-1.7	-1.3	-1.6	-1.3	-1.5
Supplements: Calcium	2.0	2.2	5.2	1.4	2.3	1.6	1.6	1.8	1.1	1.7	1.7	1.4	1.1	1.0	1.3	1.7	1.1	1.3	1.0	1.4	1.8
Basal cell carcinoma (self-reported)	2.0	2.4	5.2	-1.5	-1.8	-1.7	-1.7	-1.9	-2.3	-1.6	-1.3	-1.2	-0.4	-1.3	-1.4	-1.9	-0.8	-1.6	-1.2	-0.9	-2.2
Hip circumference	1.9	8.3	14.3	3.1	2.0	3.2	2.8	2.9	1.6	3.3	3.0	2.9	2.9	3.4	2.8	2.8	2.6	3.6	2.4	1.7	3.8
Ever highly irritable/argumentative for 2 days	1.9	2.3	5.8	-1.8	-2.4	-1.1	-1.8	-1.1	-1.3	-1.2	-2.1	-1.5	-2.1	-1.1	-1.0	-1.0	-1.6	-1.5	-0.6	-1.5	-1.1
Knee pain experienced in last month	1.9	3.0	6.6	-1.7	-1.5	-2.1	-1.6	-1.5	-1.7	-2.0	-2.0	-2.2	-1.7	-0.8	-1.3	-1.8	-2.0	-2.6	-0.4	-0.8	-1.9
Medication: Bendroflumethiazide	1.9	2.8	4.4	-1.6	-1.8	-2.0	-2.1	-1.7	-0.1	-2.0	-2.0	-1.8	-1.4	-1.7	-1.9	-1.8	-1.8	-1.5	-0.9	-1.6	-1.5
Angina	1.8	2.4	6.4	1.1	2.0	1.3	2.0	0.9	0.2	0.5	2.0	1.7	0.6	2.0	1.6	1.1	1.2	1.4	2.1	2.5	1.2
Frequency of tenseness / restlessness in last 2 weeks	1.8	2.8	10.5	-2.2	-1.6	-1.1	-1.3	-1.3	-1.0	-1.5	-1.9	-1.9	-3.2	-0.9	-1.1	-1.0	-2.4	-2.0	-0.9	-1.9	-0.8
Mouth/teeth dental problems: Dentures	1.8	3.1	5.8	-1.6	-2.4	-2.0	-2.4	-1.7	-1.5	-1.8	-2.0	-1.6	-1.5	-1.7	-1.6	-1.9	-2.1	-1.1	-1.6	-1.3	-1.1
Medication: Lansoprazole	1.8	2.0	7.6	0.9	2.3	1.3	1.9	0.9	0.3	0.6	1.5	1.0	0.7	1.7	1.7	1.2	1.2	0.7	1.6	2.7	0.9
Pulse wave Arterial Stiffness index	1.8	2.1	5.5	-1.2	-1.1	-1.9	-1.8	-1.7	-0.7	-1.3	-1.4	-1.4	-0.1	-1.4	-2.0	-2.0	-0.9	-1.6	-0.8	-0.8	-2.3
Miserableness	1.8	3.2	8.6	-1.6	-2.0	-1.0	-1.6	-1.0	-1.1	-1.4	-2.0	-1.8	-2.9	-1.9	-1.5	-1.1	-1.6	-2.2	-1.9	-2.9	-0.9
Hand grip strength (left)	1.7	4.6	9.6	2.8	2.0	2.2	1.9	2.2	1.8	2.3	2.5	2.3	2.9	1.4	2.0	1.9	3.1	2.5	1.1	1.3	1.1
Forced expiratory volume in 1-second (FEV1)	1.7	5.6	8.2	2.1	2.7	2.7	2.7	2.1	1.9	2.5	2.3	2.4	2.2	2.1	2.9	2.5	2.0	2.5	2.4	2.3	2.3
Comparative height size at age 10	1.7	9.3	24.2	3.5	2.0	2.6	2.3	2.8	4.9	3.8	3.5	3.3	4.2	2.4	2.5	2.8	2.6	3.6	1.7	1.4	3.0
Ever had prostate specific antigen (PSA) test	1.7	1.9	5.4	-0.8	-2.3	-1.7	-1.6	-1.3	-0.8	-0.9	-1.2	-1.4	0.5	-1.7	-2.0	-1.7	-0.6	-0.6	-0.4	-1.0	-2.1
Neuroticism	1.6	3.9	6.6	-2.3	-1.9	-1.7	-1.5	-1.8	-1.6	-1.9	-1.8	-1.9	-2.5	-1.8	-2.1	-1.6	-2.2	-2.6	-1.6	-2.5	-1.9
Chronic bronchitis/emphysema (father)	1.6	1.9	3.9	-1.2	-1.9	-1.2	-1.7	-1.2	-1.6	-1.2	-1.2	-1.0	-1.9	-1.0	-1.2	-1.2	-1.1	-1.3	-1.2	-2.0	-1.2
Trunk fat mass	1.6	6.8	14.5	2.8	1.4	2.8	2.1	2.7	1.9	2.8	2.5	2.5	1.8	3.8	3.1	2.7	2.5	3.1	2.0	0.9	3.5
Hair/balding pattern: Pattern 2	1.6	2.1	3.3	-1.6	-1.4	-1.5	-1.5	-1.8	-1.3	-1.5	-1.6	-1.5	-0.4	-1.8	-1.7	-1.6	-1.5	-1.1	-1.1	-0.5	-1.7
Loneliness, isolation	1.6	2.2	7.8	-1.7	-1.9	-1.0	-0.7	-1.1	-0.8	-1.5	-1.4	-1.6	-2.8	-2.0	-1.3	-1.0	-1.5	-1.3	-0.7	-1.8	-0.9
Number of self-reported non-cancer illnesses	1.6	2.8	5.1	1.8	1.3	1.9	1.9	2.2	0.4	1.4	2.0	1.7	-0.4	1.7	1.3	2.2	1.6	1.2	2.1	1.5	2.1
Pain type(s) experienced in last month: Hip pain	1.6	2.1	3.2	-1.2	-1.6	-1.8	-1.7	-1.3	-1.0	-1.7	-1.2	-1.4	-1.1	-1.3	-1.7	-1.6	-1.4	-1.1	-1.3	-1.6	-1.7
Risk taking	1.6	2.4	5.7	-1.4	-1.9	-1.3	-1.3	-1.2	-2.0	-1.6	-1.6	-1.1	-1.6	-1.5	-1.0	-1.2	-0.6	-1.7	-1.4	-2.4	-1.9
Breast Cancer	1.5	3.5	6.8	-1.9	-2.1	-2.0	-2.0	-1.7	-0.3	-1.5	-2.3	-2.0	-1.6	-2.3	-2.6	-1.7	-1.6	-1.7	-1.4	-2.1	-1.9
Heel bone mineral density (BMD) T-score, automated (right)	1.5	3.3	6.2	-1.9	-1.6	-1.8	-1.7	-1.5	-2.5	-2.1	-2.0	-2.5	-2.4	-1.0	-1.2	-1.6	-2.1	-1.9	-1.8	-1.0	-1.3
Serious illness, injury or assault of a close relative in last 2 years	1.5	1.7	3.7	-1.1	-1.5	-1.1	-1.4	-1.2	-1.8	-1.1	-1.1	-1.0	-1.6	-1.3	-1.4	-1.3	-1.0	-0.9	-1.4	-1.9	-1.1
Vascular/heart problems diagnosed by doctor	1.5	4.2	7.8	-2.4	-0.8	-2.2	-1.9	-2.3	-2.0	-1.6	-2.2	-1.9	-0.5	-2.3	-1.6	-2.2	-2.0	-2.4	-2.8	-1.8	-2.4
Impedance of whole body	1.5	7.6	10.8	2.5	3.1	2.7	2.8	2.5	2.2	2.8	2.8	2.9	2.6	2.8	3.3	2.9	2.0	2.8	2.6	3.2	2.7
HDL Cholesterol	1.4	2.3	6.1	1.5	1.0	1.6	1.4	1.4	-0.1	1.8	1.5	1.6	1.7	1.1	1.1	1.5	1.6	2.5	1.2	1.3	1.9
Alcohol intake versus 10 years previously	1.4	2.1	4.4	-1.0	-2.1	-1.2	-1.6	-1.1	-2.1	-1.6	-1.8	-1.2	-2.1	-0.9	-1.4	-1.2	-0.8	-1.2	-1.0	-1.5	-1.0
Frequency of tiredness / lethargy in last 2 weeks	1.4	2.2	10.4	-1.8	-1.7	-0.8	-1.2	-0.7	0.2	-1.2	-1.7	-1.2	-3.2	-0.7	-0.3	-0.4	-1.3	-2.1	-1.0	-2.8	-0.5
Angina (self-reported)	1.4	1.8	5.3	0.9	1.9	1.1	1.8	0.6	-0.0	0.3	1.8	1.4	0.5	1.8	1.4	0.8	1.0	1.3	1.9	2.3	1.0
Trunk fat percentage	1.3	5.2	13.3	2.3	1.4	2.5	1.9	2.4	1.4	2.3	2.2	2.1	1.2	3.6	3.0	2.4	1.9	2.6	1.9	1.1	3.2
Impedance of arm (right)	1.3	6.2	9.4	2.2	2.7	2.3	2.6	2.5	2.5	2.5	2.3	2.3	2.3	3.0	3.1	2.7	1.4	2.2	2.4	2.5	2.9
Seen a psychiatrist for nerves, anxiety, tension or depression	1.3	1.7	7.6	-1.6	-1.1	-0.9	-1.2	-1.0	-1.1	-1.2	-0.9	-1.0	-2.8	-0.7	-0.7	-0.7	-1.9	-1.7	-1.3	-1.6	-0.4
Wheeze or whistling in the chest in last year	1.3	2.3	6.8	0.8	1.7	1.6	1.8	1.4	1.1	1.3	1.1	1.3	0.1	2.2	1.8	1.8	0.6	0.7	2.6	1.6	1.8
Reason for reducing amount of alcohol drunk: Health precaution	1.3	1.6	3.1	0.8	1.5	1.2	1.5	1.2	1.1	1.3	1.1	1.0	1.3	1.0	1.7	1.3	0.9	0.8	1.8	1.4	1.1
Shortness of breath walking on level ground	1.3	1.6	4.4	-1.4	-1.7	-1.0	-0.9	-1.1	-0.8	-1.5	-0.9	-1.4	-2.1	-0.6	-1.2	-1.3	-1.3	-1.5	-0.1	-1.3	-1.2
Reaction Time	1.2	2.2	4.3	1.6	1.5	1.4	2.0	1.1	0.4	1.0	2.0	2.1	1.0	1.6	1.7	1.2	1.3	2.1	1.1	1.2	1.4
Heel T-Score	1.2	9.5	15.9	-3.5	-2.5	-3.3	-2.9	-3.4	-3.5	-3.3	-2.9	-4.0	-2.1	-1.7	-2.0	-3.3	-3.4	-3.2	-3.8	-2.5	-2.9
Average weekly spirits intake	1.2	1.5	2.2	1.4	1.0	1.5	1.5	1.4	1.4	1.4	1.3	1.1	0.8	1.4	1.2	1.3	1.3	1.0	1.3	0.3	1.0
Ever unenthusiastic/disinterested for a whole week	1.2	1.4	3.2	1.1	1.8	0.9	1.5	1.2	1.1	0.8	1.4	1.3	0.0	1.5	1.5	1.2	0.7	0.8	0.9	0.7	1.7
Weight	1.2	5.8	10.0	2.8	1.2	2.7	1.9	2.6	2.0	2.8	2.4	2.5	1.9	3.1	2.4	2.5	2.6	3.1	1.5	0.3	3.2
Worrier / anxious feelings	1.2	2.3	4.8	-1.8	-1.8	-1.0	-1.5	-1.1	-0.9	-1.1	-1.7	-1.9	-2.2	-1.7	-1.5	-1.0	-1.6	-1.9	-0.7	-1.5	-1.4
Tense / ‘highly strung’	1.2	2.0	4.9	-1.7	-1.0	-1.4	-1.1	-1.1	-1.1	-1.3	-1.1	-1.4	-1.7	-1.3	-1.4	-1.0	-1.5	-2.2	-1.1	-1.3	-1.7
High blood pressure (siblings)	1.2	1.8	5.0	-1.3	-1.1	-1.0	-0.9	-1.1	-1.1	-1.7	-1.0	-1.1	-1.8	-1.2	-1.3	-1.1	-1.0	-1.6	-0.7	-2.2	-1.7
Whole body fat mass	1.2	4.9	11.1	2.4	0.9	2.5	1.8	2.4	1.4	2.4	2.2	2.1	1.3	3.3	2.6	2.3	2.2	2.7	1.7	0.5	3.1
Number of operations (self-reported)	1.2	1.8	2.8	1.0	1.6	1.5	1.6	1.3	0.9	1.5	1.6	1.6	1.1	1.6	1.7	1.4	1.1	1.2	0.9	0.5	1.4
Blood Red Count	1.1	10.2	14.6	2.9	3.6	3.2	3.4	3.1	1.9	2.9	3.5	3.1	2.5	3.1	3.8	3.0	3.6	2.9	3.7	3.8	2.6
Lung FEV1/FVC ratio	1.1	5.4	10.7	2.4	3.3	2.2	2.4	2.0	1.3	1.8	2.6	2.5	2.0	2.2	2.1	2.2	1.9	2.4	2.6	3.2	2.2
Medication: Atenolol	1.1	1.4	3.3	1.1	1.2	1.3	1.5	1.6	1.8	1.2	1.5	0.9	0.6	0.9	0.7	1.5	1.1	0.3	1.4	0.3	0.7
Qualifications: College or University degree	1.1	3.4	8.2	2.3	2.6	0.9	1.9	1.9	1.8	2.1	1.8	1.4	2.9	1.3	1.3	1.5	1.4	2.3	1.1	1.8	1.9
Migraine (self-reported)	1.1	1.4	6.1	-0.7	-1.3	-1.0	-1.0	-0.1	-0.3	-0.8	-0.9	-1.6	-2.5	-1.5	-1.4	-0.6	-0.5	-1.4	-1.3	-1.5	-0.4
Alcohol intake frequency.	1.1	2.5	11.4	-1.5	-1.5	-1.8	-1.7	-1.2	-1.2	-2.0	-1.4	-1.4	-3.4	-0.9	-1.1	-1.1	-1.3	-1.7	-1.3	-1.1	-0.5
Long-standing illness, disability or infirmity	1.1	1.6	3.2	1.1	0.8	1.4	1.1	1.4	-0.5	1.3	1.3	1.5	0.1	1.5	1.5	1.5	0.5	0.9	1.7	1.8	1.7
Triglycerides	1.0	1.7	4.1	-1.4	-1.0	-1.3	-1.3	-1.1	0.0	-1.5	-1.6	-1.4	-2.0	-0.4	-1.0	-1.1	-1.3	-2.0	-1.0	-1.3	-1.1
Frequency of depressed mood in last 2 weeks	1.0	1.4	4.6	-1.2	-1.4	-1.2	-0.9	-1.1	-1.3	-0.9	-1.1	-0.9	-2.1	-0.9	-1.3	-0.9	-1.5	-1.0	-0.7	-1.3	-0.3
Ever used hormone-replacement therapy (HRT)	1.0	1.2	3.0	-1.4	-1.1	-1.5	-0.8	-1.4	-0.4	-1.1	-1.0	-0.9	-0.8	-0.8	-1.0	-1.2	-1.7	-0.8	-1.4	-1.3	-0.4
High blood pressure	1.0	2.8	4.7	2.0	0.5	1.9	1.5	2.0	1.9	1.2	1.8	1.6	0.2	1.7	1.1	1.8	1.5	2.0	2.1	1.5	2.2
Supplements: Glucosamine	1.0	1.2	4.7	-0.8	-1.3	-1.5	-1.0	-0.7	0.5	-0.9	-1.4	-1.4	-0.6	-0.3	-0.9	-0.8	-1.1	-1.3	-1.1	-2.2	-0.7
Forced vital capacity (FVC)	1.0	3.9	5.7	1.7	2.0	2.4	2.3	1.8	2.1	2.4	1.9	2.0	2.1	1.6	2.4	2.2	1.5	2.0	1.6	1.2	2.0
Qualifications: None of the above	1.0	2.2	5.3	-1.7	-2.3	-1.4	-1.6	-1.6	-0.3	-1.9	-1.7	-1.9	-1.9	-1.0	-1.0	-1.4	-2.0	-1.0	-0.7	-0.8	-0.9
Glaucoma (self-reported)	1.0	1.2	3.8	-1.1	-0.8	-1.0	-0.7	-1.0	1.1	-1.3	-1.0	-0.5	-1.8	-0.5	-0.7	-0.8	-1.2	-1.1	-1.6	-1.9	-0.4
Leg fat mass (right)	1.0	3.9	8.7	2.1	0.5	2.3	1.4	2.1	0.8	2.0	1.8	2.0	0.8	3.0	2.5	2.1	2.1	2.5	1.5	0.2	2.9
Leg fat mass (left)	1.0	3.9	8.6	2.1	0.6	2.3	1.5	2.1	0.6	2.1	1.9	2.0	0.9	2.9	2.4	2.0	2.1	2.6	1.5	0.3	2.9
Alzheimer’s Disease (in father)	0.9	1.0	1.7	-0.7	-1.3	-0.9	-0.7	-1.1	-1.2	-1.2	-1.0	-1.3	-1.1	-0.7	-0.6	-1.2	-1.3	-0.7	-1.0	-0.5	-0.3
Alzheimer’s Disease (including proxy)	0.9	1.3	2.7	-0.8	-1.6	-1.2	-1.1	-0.7	-0.7	-1.0	-1.5	-1.4	-1.3	-1.0	-1.0	-0.8	-1.4	-1.0	-1.2	-1.6	-0.5
Lupus	0.9	1.4	3.4	1.1	0.7	1.4	1.2	1.0	1.8	1.2	0.5	1.2	1.1	1.4	1.3	1.3	0.3	1.5	1.2	0.5	1.5
Diabetes (mother)	0.9	1.2	5.0	-1.0	-2.0	-0.9	-0.8	-0.7	0.1	-0.6	-0.9	-1.1	-1.3	-0.4	-0.3	-0.8	-0.6	-1.3	-0.9	-2.2	-1.2
Tinnitus: Yes, but not now, but have in the past	0.9	1.0	3.5	-0.8	-1.9	-0.7	-1.1	-0.8	-0.7	-1.1	-1.2	-1.0	-1.6	-0.1	-1.0	-0.7	-1.1	-1.0	-0.2	-0.8	-0.5
Waist circumference	0.9	3.4	7.0	2.2	0.7	2.1	1.4	2.0	0.9	1.8	2.1	2.0	0.8	2.6	1.9	1.8	2.0	2.2	1.1	0.6	2.6
Past tobacco smoking	0.9	1.6	5.0	0.8	2.2	1.1	1.7	0.9	0.4	1.3	1.4	0.8	1.4	1.3	1.0	1.0	0.9	1.0	1.4	1.9	0.9
Medication: Ramipril	0.9	1.1	3.4	-1.2	-1.5	-0.8	-1.3	-1.0	-1.8	-0.9	-1.0	-1.3	-0.8	-0.5	-1.2	-0.9	-1.1	-0.7	-0.4	-0.5	-0.9
Number of live births	0.9	1.2	3.4	-0.5	-1.8	-1.2	-1.5	-1.3	-0.4	-1.0	-0.7	-0.8	-0.3	-1.0	-1.2	-1.4	-0.4	-0.4	-1.3	-1.1	-1.6
Depression (self-reported)	0.9	1.0	3.3	-0.8	-0.2	-1.1	-0.7	-0.9	-1.5	-1.4	-0.6	-0.6	-1.7	-1.1	-0.4	-0.9	-1.0	-0.8	-1.8	-0.8	-0.3
Body fat percentage	0.9	3.5	10.5	1.8	0.8	2.1	1.5	2.0	0.7	1.8	1.7	1.6	0.6	3.2	2.6	2.0	1.6	2.1	1.6	0.6	2.8
Major Depression (MDD)	0.8	1.0	3.0	-0.7	-1.2	-0.8	-0.6	-0.5	-0.3	-1.0	-0.8	-1.4	-1.7	-1.0	-1.1	-0.9	-1.0	-1.4	-1.0	-1.0	-0.8
LDL Cholesterol	0.8	1.3	4.0	-0.9	0.3	-1.3	-1.1	-0.9	-1.0	-1.8	-0.9	-1.2	-1.2	-1.1	-1.2	-1.0	-0.3	-2.0	-0.7	-0.2	-1.7
Hearing difficulty/problems: Yes	0.8	1.2	2.1	-1.5	-0.8	-1.3	-1.2	-1.1	-0.1	-1.1	-1.3	-1.4	-0.9	-1.0	-0.8	-1.1	-1.2	-1.3	-1.3	-0.8	-1.1
Current tobacco smoking	0.8	1.4	5.5	-0.8	-1.1	-1.2	-0.8	-0.4	0.6	-1.1	-1.1	-1.3	-2.2	-0.8	-0.8	-0.7	-0.9	-1.2	-0.9	-2.3	-0.8
Frequency of unenthusiasm / disinterest in last 2 weeks	0.8	1.1	3.5	-1.2	-1.1	-0.9	-0.8	-0.6	0.1	-0.7	-1.2	-1.2	-1.9	-0.4	-0.8	-0.5	-1.4	-1.4	-0.5	-1.8	-0.4
Alcohol usually taken with meals	0.8	1.3	2.2	1.3	1.4	1.3	1.2	1.0	0.9	1.1	1.0	1.2	1.0	0.9	1.3	1.1	1.0	1.3	0.4	1.2	1.5
Diabetes (self-reported)	0.8	1.3	4.0	-1.0	-1.0	-1.2	-1.5	-0.8	-0.6	-1.4	-1.2	-0.9	-2.0	-1.1	-1.2	-1.1	-0.7	-1.2	-0.8	-0.7	-1.0
Impedance of arm (left)	0.8	3.9	6.2	1.7	2.5	1.8	2.0	1.8	1.8	2.0	1.9	1.9	2.1	2.3	2.3	2.1	1.2	1.9	1.7	2.3	2.0
Worry too long after embarrassment	0.8	1.3	4.1	1.2	0.9	1.2	1.0	1.7	1.5	1.6	0.9	0.8	0.2	1.1	0.7	1.6	0.6	0.7	0.8	0.3	2.0
Illnesses of siblings: Diabetes	0.8	1.0	5.8	-0.5	-1.1	-0.7	-1.1	-0.6	-1.3	-1.3	-0.6	-0.5	-2.4	-0.3	-0.6	-0.8	-0.2	-0.9	-0.9	-1.1	-0.8
Tinnitus: Yes, now most or all of the time	0.8	0.9	2.7	1.2	0.6	1.1	0.8	1.3	-0.8	0.9	1.6	1.2	0.1	0.9	0.5	1.0	1.7	1.0	0.4	0.5	0.6
Crohns Disease (2017)	0.7	1.4	3.9	-1.0	-1.5	-1.0	-1.1	-1.0	-0.7	-1.2	-1.2	-1.0	-1.4	-1.3	-0.8	-1.1	-0.9	-1.4	-1.2	-2.0	-1.2
Smoking Status	0.7	1.7	6.9	-0.8	-1.9	-1.1	-1.0	-0.4	-0.1	-1.2	-1.3	-1.0	-2.6	-0.7	-0.8	-0.7	-0.5	-1.5	-0.8	-2.6	-1.2
Diverticular disease/diverticulitis (self-reported)	0.7	0.8	2.2	0.8	-0.1	0.9	0.1	0.6	0.2	1.0	0.4	1.2	1.5	1.1	1.2	0.7	0.3	1.4	0.8	0.7	1.3
Sitting height	0.7	4.6	14.0	2.6	0.7	2.0	1.3	2.4	3.7	2.9	1.7	2.0	2.4	1.6	1.3	2.4	1.9	3.0	1.1	-0.4	2.5
Medication: Simvastatin	0.7	1.0	2.6	1.0	0.8	1.1	0.7	0.9	0.9	0.7	1.3	1.3	0.5	0.8	0.8	0.9	1.1	1.2	1.1	1.6	0.9
Breastfed as a baby	0.7	0.9	3.9	0.9	0.9	0.4	0.9	0.6	-0.1	1.0	1.2	0.5	2.0	0.6	0.6	0.5	0.8	1.0	0.4	2.0	0.3
Medication: Paracetamol	0.7	1.1	2.8	-1.2	-0.8	-0.8	-0.2	-1.0	-0.6	-1.2	-0.6	-1.2	-1.7	-1.0	-0.9	-0.9	-1.6	-0.8	-1.0	-1.5	-0.4
Headache pain in last month	0.7	1.2	6.2	-1.3	-0.5	-0.8	-0.6	-0.6	-0.4	-1.3	-1.3	-1.5	-2.5	-1.1	-0.8	-0.7	-1.2	-1.3	-0.6	-0.7	-0.1
Leg fat percentage (right)	0.7	2.5	7.1	1.5	0.4	1.9	1.1	1.6	-0.2	1.3	1.4	1.5	0.4	2.7	2.3	1.5	1.6	2.0	1.4	0.4	2.4
Number of full brothers	0.7	0.9	2.7	0.2	0.3	1.6	1.4	0.6	0.5	0.7	0.8	1.1	-0.6	1.1	1.2	0.9	0.9	0.7	1.6	0.5	1.0
Age at last live birth	0.7	1.0	2.2	-1.0	-1.1	-0.7	-1.1	-0.4	-1.2	-0.5	-1.2	-1.4	-1.5	-1.1	-0.7	-0.5	-1.0	-1.0	-0.6	-1.0	-0.8
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.7	0.9	2.2	-1.2	-1.1	-0.8	-0.8	-1.0	-0.4	-0.9	-1.3	-1.1	-0.7	-1.5	-0.8	-0.8	-0.7	-0.7	-0.5	-0.6	-1.0
Smoking status: Previous	0.7	1.1	4.3	-0.5	-2.1	-0.8	-1.5	-0.7	-0.8	-1.0	-1.0	-0.4	-0.9	-1.2	-0.9	-0.9	-0.3	-0.8	-1.0	-1.3	-1.1
Diastolic blood pressure, automated reading	0.7	2.1	4.4	1.8	0.4	1.9	1.4	1.7	0.2	1.6	1.3	1.5	0.6	2.1	1.4	1.7	1.5	1.7	1.0	-0.2	2.0
Pack years of smoking	0.7	1.0	4.1	-0.7	-2.0	-0.8	-1.2	-0.4	-0.5	-0.7	-1.4	-1.0	-0.9	-0.7	-0.8	-0.6	-0.9	-1.0	0.5	-0.9	-1.1
Crohns Disease (2012)	0.6	0.9	3.7	-0.9	-0.6	-0.6	-1.0	-1.3	-0.7	-0.9	-0.9	-0.8	-0.2	-1.2	-0.6	-1.2	-1.0	-0.7	-1.9	-1.0	-0.6
Fasting Glucose	0.6	0.7	2.2	-0.3	-1.5	-0.8	-0.9	-0.9	-1.4	-0.4	-0.5	-0.5	-0.4	-1.0	-0.8	-1.1	-0.3	-0.1	-1.0	-0.6	-0.8
Sensitivity / hurt feelings	0.6	1.1	3.6	1.2	0.9	1.0	1.3	1.5	0.6	1.1	1.0	1.0	0.2	1.2	0.8	1.4	0.3	0.5	0.8	0.4	1.9
Taking other prescription medications	0.6	0.9	2.7	0.9	0.8	0.6	0.9	1.1	0.3	0.7	1.1	0.4	0.1	1.6	0.6	1.0	0.3	0.5	1.3	1.1	1.4
Nervous feelings	0.6	1.1	2.1	-1.4	-0.8	-0.8	-1.1	-1.0	-0.4	-1.1	-0.7	-0.9	-1.5	-0.9	-1.0	-0.8	-1.4	-1.3	-1.1	-1.1	-1.0
Heart attack	0.6	0.8	4.3	-0.7	-1.6	-0.3	-0.8	-0.8	-2.1	-1.0	-1.0	-0.9	-0.8	0.4	-0.5	-0.5	-1.3	-0.6	0.2	-0.1	-0.2
Illnesses of siblings	0.6	0.8	3.9	0.5	1.1	0.2	0.8	0.1	1.1	0.9	0.4	0.4	2.0	0.8	1.1	0.2	0.2	0.8	-0.2	1.3	1.1
Neuroticism score	0.6	1.2	5.5	-1.3	-1.0	-0.5	-0.4	-0.5	-0.8	-0.8	-0.9	-1.0	-2.3	-0.8	-0.8	-0.3	-1.6	-1.7	-0.6	-1.8	-0.2
Hair/balding pattern: Pattern 3	0.6	0.9	2.7	-1.0	-0.5	-1.0	-1.0	-0.5	0.3	-0.6	-1.4	-1.6	-1.2	-0.9	-0.3	-0.4	-1.2	-1.3	-1.0	-0.8	-0.3
Medication: Ibuprofen (e.g. Nurofen)	0.6	0.7	5.5	-0.5	-0.7	-0.1	0.3	0.0	-0.8	-0.7	-0.3	-0.4	-2.4	-0.3	-0.3	-0.0	-0.4	-1.1	-0.7	-1.9	0.0
Blood clot in the leg (DVT)	0.6	0.8	2.7	0.5	1.6	0.7	0.8	0.6	1.0	0.5	0.9	1.1	1.1	0.7	0.9	0.8	0.6	0.5	0.9	1.3	0.3
Medication for cholesterol, blood pressure or diabetes	0.6	1.0	2.4	-1.3	-0.6	-1.0	-0.7	-1.3	-1.4	-0.6	-1.2	-1.2	-0.2	-0.9	-0.9	-1.2	-1.5	-1.0	-0.8	-0.3	-0.5
Emphysema/chronic bronchitis	0.6	0.6	1.2	-0.9	-0.4	-0.9	-0.9	-0.8	-0.7	-1.0	-0.3	-0.9	-0.7	-0.8	-0.6	-0.8	-1.1	-1.1	-0.5	-0.1	-1.0
Medication: Ibuprofen	0.6	0.7	4.4	-0.5	-0.7	-0.3	0.3	0.0	-1.2	-0.6	-0.2	-0.6	-2.1	-0.2	-0.4	-0.1	-0.5	-1.3	-0.8	-1.8	-0.0
Overall health rating	0.6	1.3	12.6	-0.9	-1.6	0.1	-0.2	-0.2	-1.0	-0.8	-0.6	-0.6	-3.5	0.8	0.5	-0.0	-1.0	-1.0	0.1	-1.3	0.5
Hypertension (Self-reported)	0.6	1.6	3.0	1.5	0.3	1.5	1.1	1.5	1.4	0.8	1.4	1.2	0.0	1.4	0.8	1.4	1.1	1.6	1.7	1.2	1.7
Qualifications: nursing, teaching	0.6	0.9	4.0	0.8	1.1	0.6	0.7	0.5	1.0	1.1	0.8	1.0	2.0	1.4	0.9	0.6	0.5	0.9	0.5	0.6	0.7
Smoking status: Current	0.6	0.9	4.8	-0.6	-0.7	-0.8	-0.4	-0.2	0.7	-1.0	-0.9	-1.0	-2.2	-0.5	-0.5	-0.4	-0.8	-1.0	-0.6	-2.0	-0.4
Medication: Paracetamol	0.6	0.9	3.6	-1.0	-0.3	-0.9	0.1	-1.0	-0.7	-1.2	-0.2	-1.2	-1.1	-0.7	-0.9	-0.9	-1.9	-0.7	-1.2	-1.2	-0.1
Basal metabolic rate	0.6	3.2	6.1	2.2	0.5	2.0	1.3	1.8	2.3	2.3	1.7	1.9	1.7	1.8	1.5	1.7	2.1	2.5	0.6	-0.7	2.2
Leg fat percentage (left)	0.6	2.1	6.2	1.4	0.3	1.8	1.0	1.4	-0.5	1.3	1.3	1.3	0.3	2.5	2.0	1.4	1.5	1.9	1.4	0.5	2.2
Age started oral contraceptive pill	0.6	0.7	3.9	0.6	1.3	0.4	0.6	0.7	0.7	0.8	0.7	0.3	1.2	0.5	0.3	0.6	0.7	0.6	1.0	2.0	0.5
Heart attack/myocardial infarction (self-reported)	0.6	0.8	4.2	-0.6	-1.6	-0.3	-0.8	-0.7	-2.0	-0.9	-0.9	-0.9	-0.8	0.4	-0.5	-0.5	-1.2	-0.5	0.2	-0.3	-0.2
Arm predicted mass (left)	0.6	3.1	5.7	2.2	0.6	1.9	1.3	1.7	2.2	2.2	1.9	1.9	2.0	1.5	1.4	1.6	2.2	2.4	0.7	-0.5	1.8
Alzheimer’s Disease (in mother)	0.5	0.5	2.6	-0.5	-0.7	-0.6	-0.6	-0.1	0.1	-0.5	-1.0	-0.7	-1.3	-0.6	-0.5	-0.1	-0.6	-0.8	-0.6	-1.6	-0.1
Ulcerative Colitis	0.5	0.7	3.0	1.0	0.9	0.1	0.8	0.5	1.5	0.8	1.0	0.6	1.7	1.1	0.4	0.5	0.5	0.9	0.5	-0.2	0.4
Hair Pigment	0.5	13.1	21.9	3.6	4.7	3.7	4.0	3.0	1.6	3.4	4.3	4.5	3.7	3.5	4.2	3.3	3.4	3.9	2.2	3.2	3.4
Bilateral oophorectomy (both ovaries removed)	0.5	0.5	1.8	0.6	0.3	0.7	0.7	0.4	-0.2	0.1	0.8	0.6	-0.1	1.4	1.2	0.5	0.1	1.0	0.6	1.0	1.1
Trunk fat-free mass	0.5	2.8	5.8	2.1	0.4	1.8	1.1	1.5	2.4	2.1	1.6	1.8	2.2	1.1	1.1	1.4	2.0	2.4	0.2	-0.9	1.7
Falls in the last year	0.5	0.6	3.2	-0.8	-0.8	-0.4	-0.4	-1.1	-1.8	-1.0	-0.4	-0.5	-0.8	-0.3	-0.8	-0.8	-0.8	-0.4	-0.6	-0.6	-0.6
Arm fat mass (right)	0.5	1.9	6.0	1.4	0.3	1.5	1.0	1.4	0.8	1.4	1.2	1.2	0.5	2.5	1.7	1.4	1.2	1.6	0.8	-0.3	2.2
Trunk predicted mass	0.5	2.7	5.7	2.1	0.4	1.7	1.0	1.4	2.3	2.1	1.5	1.8	2.2	1.0	1.1	1.3	2.0	2.4	0.2	-0.9	1.6
Arm fat-free mass (right)	0.5	2.5	5.6	2.0	0.5	1.8	1.0	1.5	1.9	2.1	1.6	1.8	1.7	1.2	1.0	1.4	2.2	2.4	0.4	-0.6	1.6
Mouth/teeth dental problems: Loose teeth	0.5	0.6	1.8	-0.4	-0.8	-0.7	-1.1	-0.6	-1.4	-0.7	-0.5	-0.9	-0.3	-0.1	-0.8	-0.8	-1.3	-0.5	-0.9	-0.2	-0.6
Arm predicted mass (right)	0.5	2.4	5.0	2.1	0.5	1.7	1.0	1.5	2.0	2.0	1.6	1.7	1.9	1.0	1.0	1.4	2.2	2.2	0.5	-0.5	1.4
Family relationship satisfaction	0.5	0.6	4.8	-0.5	-1.4	-0.3	-0.6	-0.7	-2.2	-0.4	-0.7	0.0	-0.4	0.0	-0.6	-0.7	-0.4	-0.2	0.8	0.3	-0.7
Ever had bowel cancer screening	0.5	0.5	1.1	-1.0	-0.8	-0.7	-0.5	-0.8	-0.1	-0.6	-0.5	-0.7	-0.6	-0.4	-0.8	-1.0	-0.7	-1.0	-0.5	-0.7	-1.0
Ever had stillbirth, spontaneous miscarriage or termination	0.5	0.6	3.1	-0.8	-1.1	-0.3	-0.5	-0.6	-1.0	-0.6	-0.9	-0.6	-1.8	-0.3	-0.4	-0.3	-0.6	-0.9	-0.2	-0.6	-0.3
Mouth/teeth dental problems: Mouth ulcers	0.5	0.7	2.0	-1.1	-0.2	-0.8	-0.3	-0.7	-1.4	-0.6	-0.8	-0.7	-1.3	-0.3	-0.7	-0.4	-0.4	-1.4	-0.5	-0.8	-1.2
Medication for cholesterol	0.5	0.7	2.8	-0.9	0.1	-1.0	-0.5	-0.9	-1.0	-0.4	-0.9	-0.8	0.7	-1.1	-0.6	-0.8	-0.5	-1.0	-0.8	-0.3	-1.7
Arm fat mass (left)	0.5	2.0	5.5	1.5	0.4	1.6	1.0	1.5	0.7	1.5	1.3	1.4	0.6	2.3	1.7	1.5	1.4	1.7	0.9	-0.1	2.1
Arm fat-free mass (left)	0.5	2.5	5.0	2.0	0.4	1.7	1.1	1.5	2.0	2.0	1.6	1.7	1.9	1.3	1.2	1.4	1.9	2.2	0.5	-0.6	1.7
Average weekly beer plus cider intake	0.5	0.7	2.3	0.6	1.5	0.8	0.6	0.6	1.0	0.5	0.8	0.9	0.6	0.5	1.0	0.9	1.2	0.3	0.5	1.3	0.4
Unable to work because of sickness or disability	0.5	0.7	3.1	-0.9	-1.1	-0.8	-0.5	-0.7	-0.8	-0.9	-0.8	-0.6	-1.8	-0.1	-0.4	-0.6	-0.5	-0.8	-0.2	-1.2	-0.9
Alcohol drinker status: Previous	0.5	0.6	4.4	-0.2	-1.3	-0.8	-1.2	-0.1	-0.2	-0.7	-0.6	-0.5	-2.1	-0.2	-0.0	-0.1	-0.3	-0.5	-0.9	-0.6	0.2
Type 2 Diabetes (T2D) (2012)	0.4	0.5	3.0	0.6	0.4	0.5	0.3	0.6	-0.4	0.5	0.6	0.4	0.1	-0.1	0.5	0.5	1.0	0.5	1.3	1.7	0.5
Pack years adult smoking proportion	0.4	0.7	3.2	-0.5	-1.8	-0.5	-0.9	-0.2	-0.4	-0.5	-1.1	-0.8	-1.1	-0.4	-0.6	-0.3	-0.6	-0.9	0.8	-0.8	-0.9
Fed-up feelings	0.4	0.7	5.1	-0.3	-0.7	0.2	-0.2	0.3	1.1	-0.3	-0.4	-0.3	-2.3	-0.2	-0.0	0.3	-0.8	-1.0	-0.3	-1.6	0.5
Qualifications: CSEs or equivalent	0.4	0.5	1.9	0.1	1.4	0.8	0.8	0.3	0.3	0.1	0.4	0.5	-0.2	0.8	1.0	0.6	0.2	0.1	1.0	1.2	0.6
Stomach or abdominal pain in last month	0.4	0.5	3.8	0.2	0.1	0.7	0.4	0.8	0.2	0.3	0.1	0.1	-1.9	0.8	0.5	0.9	0.1	-0.5	0.7	-0.5	1.1
Hearing difficulty/problems with background noise	0.4	0.6	2.4	-1.2	-1.0	-0.3	-0.5	-0.6	0.1	-0.3	-1.0	-0.6	-1.5	-0.6	-0.4	-0.4	-0.7	-0.7	-0.2	-1.5	-0.7
Pain all over the body in last month	0.4	0.5	1.4	0.3	1.0	1.0	0.9	0.4	0.2	0.3	0.8	0.9	0.2	1.2	1.0	0.6	-0.0	0.6	-0.2	0.2	0.9
Eye problems/disorders: None of the above	0.4	0.4	1.0	-0.6	-0.7	-0.6	-0.7	-0.5	-0.2	-0.4	-0.8	-1.0	-0.3	-1.0	-0.7	-0.6	-0.6	-0.7	-0.5	0.2	-0.9
Medication for pain relief, constipation, heartburn	0.4	0.6	6.8	0.0	0.5	0.2	-0.4	-0.3	0.5	0.7	-0.1	0.5	2.6	0.3	0.4	-0.1	-0.1	0.6	0.1	1.6	-0.2
Medication: Blood pressure	0.4	0.7	2.0	1.0	0.6	0.8	0.7	0.9	1.4	0.5	1.0	0.9	0.5	0.9	0.6	0.8	0.9	0.9	0.9	0.7	0.6
Mean time to correctly identify matches	0.4	0.8	2.7	0.9	0.3	0.7	1.1	0.2	-0.1	0.4	1.4	1.6	1.1	1.2	0.7	0.3	0.8	1.6	0.3	0.3	0.6
Whole body fat-free mass	0.4	2.4	4.8	2.0	0.3	1.6	1.0	1.5	2.2	2.0	1.4	1.6	1.6	1.2	1.0	1.4	1.9	2.2	0.2	-0.9	1.8
Mood swings	0.4	0.8	3.5	-0.7	-1.4	-0.3	-0.6	-0.3	-0.7	-0.7	-0.7	-0.4	-1.9	-0.9	-1.0	-0.3	-0.5	-0.7	-0.6	-1.7	-0.6
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.4	0.9	2.4	0.4	0.9	1.5	1.4	0.7	-0.5	0.8	0.9	0.6	0.6	1.0	1.4	0.9	0.5	1.2	0.9	1.3	0.9
Whole body water mass	0.4	2.4	4.8	2.0	0.3	1.6	1.0	1.5	2.2	2.0	1.4	1.6	1.7	1.3	1.0	1.4	1.8	2.2	0.2	-0.9	1.8
Average weekly champagne plus white wine intake	0.4	0.6	1.5	-0.7	-0.1	-0.9	-0.5	-0.7	0.5	-0.9	-0.8	-1.0	-0.5	-0.4	-0.5	-0.8	-0.9	-0.9	-1.2	-1.2	-0.6
Eye problems/disorders: Glaucoma	0.4	0.5	4.4	0.1	0.6	0.0	0.5	0.2	2.1	-0.1	0.3	0.4	-0.8	0.3	0.7	0.4	0.3	-0.3	-0.5	-1.1	0.3
High cholesterol (Self-reported)	0.4	0.8	3.2	-0.7	-1.1	-0.4	-1.0	-0.8	-1.0	-1.1	-0.8	-0.3	-1.8	-1.3	-1.0	-0.8	-0.3	-0.4	0.2	-0.4	-0.9
Alcohol drinker status: Never	0.4	0.4	1.7	0.8	0.4	0.3	0.3	0.8	1.3	0.4	0.4	0.5	-0.0	0.6	0.5	0.5	0.9	0.7	0.8	0.0	1.0
Deep venous thrombosis (DVT) (self-reported)	0.4	0.5	2.2	0.4	1.5	0.6	0.7	0.4	0.5	0.2	0.7	0.9	0.5	0.5	0.6	0.6	0.3	0.3	0.8	1.2	0.4
Heart disease (siblings)	0.4	0.5	2.0	-0.5	-0.3	-0.3	-0.7	-0.8	-1.1	-0.5	-0.2	-0.2	0.7	-1.3	-0.8	-0.6	0.0	-0.1	0.5	1.1	-1.4
Verbal and Numeric Reasoning (VNR)	0.3	0.7	1.7	-0.7	-1.0	-1.0	-0.9	-0.9	-0.3	-0.6	-0.6	-0.9	0.1	-0.9	-1.0	-1.1	-0.4	-0.7	-0.9	-0.9	-1.3
Primary Biliary Cirrhosis	0.3	0.5	2.2	0.7	0.5	0.5	0.2	0.5	-0.6	0.5	0.3	0.6	1.5	0.5	0.1	0.6	0.6	0.8	1.1	1.2	0.3
Number of treatments/medications taken	0.3	0.5	1.3	0.9	0.1	0.4	0.9	1.0	0.8	0.3	1.2	0.3	-0.8	1.0	0.6	0.8	0.5	0.8	0.4	-0.2	1.1
Medication: Co-codamol	0.3	0.3	1.2	-0.6	-0.7	0.2	0.2	0.2	0.6	0.2	-0.3	-0.6	-1.1	0.5	0.2	0.4	-0.8	-0.7	0.5	-0.8	0.3
Leg fat-free mass (left)	0.3	1.5	3.3	1.5	0.2	1.2	0.7	1.3	1.8	1.6	1.0	1.2	0.8	1.4	0.9	1.2	1.3	1.7	0.1	-1.0	1.8
Townsend deprivation index at recruitment	0.3	0.5	1.1	0.5	1.0	0.6	1.0	0.6	0.8	0.4	1.0	0.7	-0.0	0.7	1.1	0.8	0.5	0.3	0.4	0.6	0.5
Heel bone mineral density (BMD) T-score, automated (left)	0.3	0.7	3.1	-0.9	-0.4	-0.5	-0.6	-0.5	-1.8	-1.0	-0.7	-1.1	-1.6	0.1	0.2	-0.5	-0.9	-1.0	-0.9	-0.3	-0.3
Multivitamins +/- minerals	0.3	0.4	1.9	0.4	0.4	0.6	0.4	0.6	-0.6	0.5	0.3	0.1	0.0	0.5	0.2	0.7	0.6	0.4	0.9	1.4	0.5
Leg predicted mass (left)	0.3	1.4	3.1	1.4	0.1	1.2	0.7	1.2	1.8	1.5	0.9	1.1	0.8	1.3	0.9	1.1	1.3	1.6	-0.0	-1.1	1.7
Financial difficulties in last 2 years	0.3	0.4	1.6	0.1	-0.1	0.5	0.6	0.2	-0.6	-0.0	0.3	0.4	-0.9	1.3	1.3	0.5	-0.1	-0.0	0.5	-0.2	0.7
Arm fat percentage (right)	0.3	1.2	6.2	0.8	0.1	1.1	0.8	1.1	-0.1	0.9	0.8	0.8	-0.2	2.5	1.6	1.0	0.7	1.1	0.9	-0.1	2.0
Length of working week for main job	0.3	0.3	1.0	0.6	0.6	0.1	0.6	0.2	0.1	0.6	1.0	0.8	1.0	0.1	0.4	0.4	0.3	0.6	-0.0	0.3	0.2
Chronic bronchitis/emphysema (mother)	0.3	0.4	1.1	0.3	0.3	0.6	1.1	0.3	0.0	1.0	0.7	0.5	1.0	1.0	0.5	0.3	-0.0	0.3	0.8	-0.4	0.5
Exposure to tobacco smoke outside home	0.3	0.4	1.6	0.6	0.4	0.4	0.6	0.4	-0.5	0.2	0.6	0.4	-0.0	1.0	0.3	0.4	0.3	0.2	0.9	1.3	0.8
Comparative body size at age 10	0.3	0.8	3.7	-0.2	-1.2	-0.9	-1.3	-0.4	-1.9	-0.4	-0.8	-0.9	-0.2	-0.7	-1.0	-0.6	0.4	-0.7	-0.7	-0.8	-1.0
Qualifications: NVQ or HND or HNC or equivalent	0.3	0.3	1.2	0.0	1.1	0.7	0.5	0.6	0.5	0.3	0.4	0.4	-0.7	0.2	1.0	0.8	0.6	-0.5	-0.4	-0.3	0.4
Arm fat percentage (left)	0.3	1.1	5.5	0.8	0.3	1.1	0.7	1.0	-0.1	0.8	0.8	0.8	-0.2	2.4	1.6	1.0	0.9	1.1	0.8	-0.1	1.8
Eye problems/disorders: Cataract	0.3	0.3	1.0	0.6	0.8	0.4	0.5	0.1	0.4	0.3	0.6	1.0	1.0	0.6	0.0	0.2	-0.1	0.8	0.0	-0.5	0.6
Illnesses of father: None of the above (group 1)	0.3	0.3	0.9	-0.6	-0.2	-0.8	-0.3	-0.8	-0.9	-0.4	-0.5	-0.4	0.2	-0.6	-0.9	-0.6	-0.9	-0.1	-0.2	0.4	-0.2
Guilty feelings	0.3	0.5	1.4	0.6	0.9	0.4	1.2	0.8	1.0	0.8	0.7	0.8	0.1	0.5	0.4	0.9	0.7	0.2	0.5	-0.6	0.7
Ever smoked	0.3	0.5	2.8	-0.0	-1.5	-0.6	-0.9	-0.3	0.5	-0.7	-0.6	-0.4	-0.6	-0.5	-0.3	-0.4	-0.2	-0.2	-1.0	-1.7	-0.5
Ever depressed for a whole week	0.3	0.3	0.8	0.5	0.7	0.3	0.8	0.9	0.9	0.3	0.7	0.5	-0.4	0.7	0.5	0.7	0.1	-0.2	0.6	-0.2	0.7
Ulcerative Colitis (UC)	0.2	0.4	1.6	0.8	0.4	-0.1	0.5	0.1	1.3	0.3	0.8	0.9	1.2	0.4	0.1	0.1	0.7	0.8	0.0	-1.0	-0.0
Ovarian Cancer	0.2	0.3	2.1	-0.1	-0.6	-0.5	-0.6	0.0	-0.0	-0.7	-0.6	-0.1	-1.4	0.0	-0.5	-0.0	0.2	-0.6	0.8	-0.2	-0.0
Body Mass Index (BMI) (2010)	0.2	0.2	1.4	0.3	-0.4	0.7	0.0	0.2	-1.2	0.3	0.4	0.3	-0.2	0.8	0.4	0.2	0.4	0.2	0.5	0.7	0.2
Mean Putamen Volume	0.2	0.2	2.2	0.1	-0.5	0.1	-0.3	0.1	1.5	0.0	-0.1	0.0	-0.2	-0.1	0.0	0.1	-0.3	0.4	-0.2	-0.4	0.6
Cardiovascular Disease	0.2	0.5	1.8	0.7	-0.1	0.8	0.7	0.6	0.6	0.2	0.7	0.5	-0.9	0.9	0.4	0.5	0.7	0.7	1.3	0.9	0.8
Lung FVC	0.2	1.2	4.8	0.2	1.1	1.5	1.8	1.0	0.2	0.7	0.8	0.8	-1.0	0.7	1.3	1.3	0.3	0.2	2.2	1.3	0.7
Eye problems/disorders: Diabetes related eye disease	0.2	0.2	0.8	0.5	-0.0	0.1	-0.1	0.4	-0.3	0.5	0.3	0.2	0.2	0.2	-0.2	0.3	0.6	0.7	0.9	0.9	0.4
Medication for hormone replacement therapy	0.2	0.2	1.1	0.4	0.6	0.0	0.1	0.2	0.3	0.5	0.4	0.1	0.7	0.5	-0.0	0.2	-0.5	0.2	-0.4	0.6	1.1
Serious illness, injury or assault to yourself	0.2	0.3	0.8	-0.1	0.7	0.3	0.2	0.0	-0.7	0.3	0.3	0.3	0.6	0.8	0.3	0.3	-0.9	0.1	0.3	0.8	0.8
Number of incorrect matches in round	0.2	0.3	0.7	0.6	0.0	0.5	0.6	0.3	-0.2	0.4	0.8	0.9	0.7	0.6	0.6	0.4	0.4	0.6	0.5	0.3	0.0
Had other major operations	0.2	0.2	1.0	0.4	0.2	0.2	0.3	0.1	-0.1	0.5	0.5	0.7	1.0	0.4	0.4	0.0	0.0	0.8	-0.3	-0.4	0.5
Father’s age at death	0.2	0.2	0.7	-0.8	0.0	-0.3	-0.2	-0.1	0.7	0.5	-0.5	-0.7	0.2	-0.0	0.1	0.2	-0.9	-0.5	-0.7	-0.6	0.2
Noisy workplace	0.2	0.3	0.9	0.8	0.4	0.7	0.3	0.7	0.0	0.3	0.9	0.5	-0.4	0.8	0.9	0.4	0.7	0.2	0.1	0.3	0.2
Qualifications: A levels/AS levels or equivalent	0.2	0.3	1.7	-0.6	-0.6	-0.4	-0.5	-0.4	0.2	-0.2	-0.8	-0.2	-0.2	-0.7	-0.3	-0.3	-0.8	-0.0	-0.9	-1.3	0.4
Prospective memory result	0.2	0.2	0.6	-0.3	0.3	-0.4	-0.3	-0.6	0.6	-0.6	0.2	-0.3	0.8	-0.2	-0.1	-0.5	-0.7	-0.2	-0.6	0.4	-0.3
Illnesses of mother	0.2	0.2	0.5	-0.4	-0.6	-0.5	-0.7	-0.7	0.0	-0.5	-0.7	-0.4	-0.5	-0.1	-0.3	-0.6	-0.5	0.2	-0.7	0.0	-0.0
Loud music exposure frequency	0.2	0.3	0.9	-0.5	-1.0	-0.3	-0.5	-0.4	0.6	-0.5	-0.7	-0.4	-0.8	-0.1	0.1	-0.4	-0.4	-0.7	-0.4	-0.5	-0.4
Mouth/teeth dental problems: Bleeding gums	0.2	0.3	1.6	0.1	-0.2	-0.2	-0.8	0.0	-0.7	-0.5	-0.3	0.1	-1.3	-0.2	-0.7	-0.1	-0.7	0.1	-0.4	0.2	0.5
Gout (self-reported)	0.2	0.3	1.8	-0.5	-0.6	-0.6	-0.3	-0.1	0.0	-0.7	-0.7	-0.9	-1.3	-0.2	-0.0	-0.1	-0.3	-0.7	-0.0	-0.1	-0.3
Age at first live birth	0.2	0.4	2.4	-0.5	0.1	-0.2	-0.5	-0.2	-1.5	-0.5	-0.7	-0.8	-0.6	-0.7	-0.3	-0.1	-0.7	-0.8	-0.6	-0.1	-0.3
Health satisfaction	0.2	0.3	1.2	0.2	-0.4	0.3	0.1	0.7	-0.8	0.4	0.2	0.3	-1.1	0.4	0.1	0.6	0.3	-0.3	0.5	-0.7	0.4
Heart disease (mother)	0.2	0.3	3.0	-0.1	-0.4	0.0	-0.3	-0.3	-1.7	-0.2	0.2	0.2	-0.0	-0.5	-0.5	-0.3	0.2	-0.1	0.6	0.8	-0.5
Chest pain or discomfort	0.2	0.3	1.3	-0.8	-0.1	-0.4	-0.3	-0.5	-0.5	-0.5	-0.5	-0.3	-1.1	0.4	0.2	-0.2	-0.6	-1.0	-0.1	-0.3	-0.1
Commuting to job workplace: Car/motor vehicle	0.2	0.2	1.3	0.3	-0.8	0.1	-0.1	0.3	-1.1	-0.1	-0.2	-0.8	-0.3	0.3	-0.5	0.1	0.5	0.4	0.4	0.3	0.2
Illness, injury, bereavement, stress in last 2 years	0.2	0.3	2.1	0.9	0.6	0.1	-0.0	0.5	0.4	0.4	0.2	0.1	1.4	-0.2	-0.4	0.2	0.7	0.1	-0.1	0.7	-0.1
Illnesses of father: Heart disease	0.2	0.3	0.9	0.7	0.3	0.9	0.4	0.7	-0.3	0.8	0.5	0.2	1.0	0.1	0.3	0.4	0.9	-0.2	0.4	0.7	-0.0
Leg fat-free mass (right)	0.2	1.0	2.2	1.2	0.1	1.0	0.5	1.0	1.5	1.4	0.8	0.9	0.7	1.0	0.5	0.9	1.1	1.4	-0.1	-1.0	1.3
Handedness (chirality/laterality): Left-handed	0.2	0.2	0.7	0.6	0.5	0.3	0.3	0.7	-0.0	0.5	0.8	0.4	0.5	0.3	0.4	0.6	0.7	0.3	-0.5	0.1	0.3
Diabetes diagnosed by doctor	0.2	0.3	2.2	-0.1	-0.7	-0.4	-0.9	-0.0	-0.5	-0.5	-0.3	-0.3	-1.5	-0.4	-0.6	-0.3	0.3	-0.4	0.1	0.2	-0.4
Commuting to job workplace: Walk	0.2	0.2	0.7	-0.5	0.5	-0.1	0.4	-0.5	0.9	-0.5	0.1	0.2	-0.6	-0.1	0.3	-0.2	-0.7	-0.4	-0.3	-0.5	-0.0
Breast cancer (self-reported)	0.2	0.3	1.2	0.2	-0.4	-0.4	-0.5	-0.4	-0.9	-0.2	0.2	-0.1	1.1	0.1	-0.1	-0.6	-0.1	0.4	-0.2	1.1	-0.2
Leg predicted mass (right)	0.2	1.0	2.3	1.2	0.1	1.0	0.5	1.0	1.5	1.3	0.7	0.8	0.7	1.0	0.5	0.9	1.1	1.4	-0.1	-1.0	1.3
Financial situation satisfaction	0.2	0.3	2.7	0.0	-0.9	0.3	-0.1	-0.2	-1.6	0.1	0.0	0.4	0.2	0.5	0.6	0.1	0.1	0.2	0.3	-0.2	0.2
Commuting to job workplace: Public transport	0.2	0.2	0.8	0.0	0.9	-0.0	0.4	-0.5	0.3	-0.2	0.5	0.8	0.4	0.0	0.2	-0.4	-0.0	0.5	-0.6	0.5	0.2
Medication: Blood pressure	0.2	0.4	1.3	0.9	-0.2	0.5	0.2	0.8	0.7	-0.0	0.6	0.5	-0.7	0.5	0.3	0.6	0.5	0.8	1.2	0.2	1.1
Illnesses of father: High blood pressure	0.2	0.3	1.0	-0.3	-0.6	-0.3	-0.3	-0.1	0.6	-0.4	-0.5	-0.4	-1.0	-0.5	-0.2	-0.1	-0.0	-0.4	-0.5	-1.0	-0.5
Irritability	0.2	0.4	2.4	-0.5	-0.1	0.2	-0.0	0.0	-1.2	-0.4	-0.1	-0.4	-1.6	-0.0	-0.6	0.0	-0.4	-1.2	0.1	-0.5	-0.4
Cholesterol lowering medication	0.2	0.3	0.8	-0.3	-0.5	0.0	-0.5	-0.6	-0.8	-0.9	-0.0	0.0	-0.8	-0.6	-0.4	-0.6	-0.3	0.3	0.3	0.7	-0.3
Bipolar Disorder (2018)	0.1	0.2	1.5	-0.2	0.1	-0.3	-0.2	-0.3	-0.6	-0.1	-0.0	-0.4	0.1	-0.9	-1.2	-0.3	-0.7	-0.5	-0.1	0.2	-0.2
Intelligence (Savage-Jansen 2018)	0.1	0.2	1.3	-0.1	0.1	-0.7	-0.2	-0.5	0.3	-0.1	-0.0	-0.2	1.1	-0.2	-0.8	-0.5	-0.3	0.0	-0.6	-0.3	-0.5
Schizophrenia (2018)	0.1	0.2	0.6	0.4	-0.1	0.5	0.0	0.5	0.6	0.5	-0.2	0.5	0.2	-0.0	0.3	0.5	0.1	0.4	0.7	0.3	0.8
Schizophrenia vs Biploar Disorder	0.1	0.1	0.4	-0.2	-0.2	-0.3	0.3	-0.1	0.1	0.0	0.1	0.0	0.2	0.7	0.5	0.1	-0.1	-0.3	0.3	0.5	-0.3
Irritable Bowel Disease (IBD)	0.1	0.2	2.2	0.1	-0.2	-0.5	-0.0	-0.4	0.6	-0.2	0.1	0.1	0.5	-0.3	-0.2	-0.4	0.1	-0.1	-0.5	-1.5	-0.6
Bipolar Disorder (2011)	0.1	0.1	0.5	0.4	0.2	0.0	0.1	0.0	0.2	0.4	0.4	0.7	0.6	-0.2	-0.3	0.0	0.0	0.0	0.0	0.0	0.0
Coronary Artery Disease (CAD)	0.1	0.1	0.5	-0.0	0.6	0.0	0.5	0.2	-0.4	0.0	0.5	0.1	-0.3	0.2	-0.2	0.3	0.4	-0.7	0.7	0.4	-0.4
HbA1C	0.1	0.2	1.2	0.2	-0.3	-0.0	-0.4	0.5	-1.1	0.1	-0.1	-0.3	-0.6	-0.3	-0.0	0.2	0.4	-0.4	-0.6	-0.0	-0.2
Schizophrenia (2014)	0.1	0.3	1.3	-0.5	-1.0	-0.2	-0.3	-0.3	-0.2	-0.0	-1.0	-0.4	-0.4	-0.9	-0.5	-0.2	-1.1	-0.6	-0.0	-0.5	0.2
BMI	0.1	0.5	2.6	-0.3	-1.5	0.0	-0.5	-0.4	-1.6	-0.5	-0.2	-0.3	-1.2	0.4	-0.4	-0.6	-0.1	-0.0	-0.3	-1.0	0.3
Waist Hip Ratio (WHR)	0.1	0.2	0.9	0.5	0.0	0.0	-0.2	0.4	0.6	-0.1	0.6	0.4	-0.9	0.1	0.2	0.2	0.9	-0.4	-0.9	-0.7	-0.2
Type 2 Diabetes (T2D) (2018)	0.1	0.2	2.1	-0.1	-0.8	-0.1	-0.6	0.1	0.2	-0.4	-0.1	-0.3	-1.4	-0.1	-0.2	-0.2	0.5	-0.4	-0.1	-0.2	-0.2
Chronotype (morning person)	0.1	0.2	1.1	-0.4	-0.2	-0.1	-0.6	-0.6	-1.1	-0.1	-0.1	0.1	0.6	-0.1	-0.0	-0.5	-0.3	-0.2	-0.9	-0.2	-0.4
Vitamin and mineral supplements	0.1	0.1	0.9	-0.4	-0.3	0.1	0.3	-0.4	0.3	-0.3	-0.1	0.1	-0.7	-0.1	0.2	-0.2	-0.4	-0.1	-0.2	-0.9	-0.0
Supplements: Zinc	0.1	0.1	0.3	0.2	-0.0	0.2	-0.1	0.5	-0.3	0.5	0.1	0.1	-0.0	-0.4	-0.1	0.3	0.2	0.2	-0.5	-0.5	0.5
Diabetes (father)	0.1	0.2	0.8	-0.3	0.1	-0.4	-0.4	-0.2	0.9	-0.3	-0.2	-0.3	-0.2	0.1	0.5	-0.2	-0.7	-0.5	-0.6	-0.0	0.2
Relative age voice broke	0.1	0.1	0.3	-0.4	-0.3	0.2	0.0	-0.2	0.4	-0.1	-0.5	-0.2	-0.0	-0.5	-0.5	-0.0	0.0	0.0	0.5	0.2	-0.5
Age when periods started (menarche)	0.1	0.3	0.9	0.3	0.1	1.0	0.7	0.6	0.7	0.3	0.5	0.5	-0.5	0.8	0.6	0.9	0.3	0.3	0.6	0.1	0.7
High blood pressure (mother)	0.1	0.1	0.5	-0.1	0.4	0.3	0.3	0.2	0.6	-0.3	0.1	-0.1	-0.7	-0.2	0.3	0.1	-0.1	-0.3	-0.3	-0.4	0.1
Body mass index (BMI)	0.1	0.3	1.2	0.1	-0.8	0.4	-0.1	0.3	-0.9	0.0	-0.0	0.0	-1.1	1.1	0.4	0.2	0.3	0.2	0.2	-0.8	0.8
Had menopause	0.1	0.1	0.4	-0.4	-0.3	-0.6	-0.2	-0.6	0.6	-0.3	-0.0	-0.1	0.6	-0.0	-0.2	-0.6	-0.5	-0.0	-0.2	-0.2	-0.4
Fluid intelligence score	0.1	0.2	0.6	-0.5	-0.5	-0.5	-0.3	-0.4	0.2	-0.1	-0.3	-0.6	-0.3	-0.3	-0.8	-0.6	-0.4	-0.5	-0.2	-0.3	-0.4
Medication: Cholesterol lowering	0.1	0.2	1.0	0.5	0.2	0.3	0.0	0.5	-0.3	-0.0	0.5	0.6	-0.3	0.3	0.4	0.5	1.0	0.3	0.5	0.0	-0.3
Exposure to tobacco smoke at home	0.1	0.1	0.9	0.3	-0.0	-0.1	0.0	0.2	-0.1	0.3	0.2	-0.2	0.4	0.0	-0.1	0.1	0.2	0.2	1.0	0.6	0.0
Hair/balding pattern: Pattern 4	0.1	0.2	1.0	-0.2	0.2	0.3	0.5	0.3	0.3	-0.2	0.4	0.3	-1.0	0.2	0.4	0.3	-0.5	-0.5	-0.4	-0.6	0.8
Pulse wave reflection index	0.1	0.2	0.9	0.1	0.6	-0.2	-0.2	0.2	0.9	0.5	-0.1	-0.0	0.9	0.3	0.3	0.2	0.1	-0.4	0.1	0.3	-0.0
Qualifications: O levels/GCSEs or equivalent	0.1	0.1	0.6	-0.3	0.3	0.0	0.2	-0.3	0.1	-0.2	-0.4	0.2	0.1	-0.4	-0.1	-0.3	0.1	-0.1	-0.3	-0.8	-0.2
Number of children fathered	0.1	0.1	0.8	-0.1	-0.3	-0.1	-0.3	-0.3	-0.1	-0.2	-0.5	-0.3	-0.2	-0.3	-0.2	-0.3	-0.3	0.1	-0.9	-0.3	0.0
Medication: Allopurinol	0.1	0.2	0.9	-0.3	-0.9	-0.2	-0.4	-0.1	0.3	-0.3	-0.6	-0.5	-0.9	-0.1	-0.1	-0.1	-0.3	-0.0	-0.1	-0.2	0.0
Medication: Seretide 50 evohaler	0.1	0.1	1.3	-0.1	0.0	0.3	0.4	0.1	-0.4	0.2	-0.2	-0.1	-0.1	-0.3	0.1	0.3	0.0	-0.0	1.1	0.4	-0.1
Number of full sisters	0.1	0.2	0.9	0.3	0.0	-0.4	-0.2	-0.2	-0.9	-0.4	0.1	-0.0	0.0	0.2	0.0	-0.2	0.2	0.8	-0.4	0.7	0.3
Medication: Aspirin	0.1	0.1	0.6	0.4	0.0	0.1	0.4	0.3	0.1	-0.4	0.5	-0.1	-0.8	0.2	0.1	0.2	0.5	0.2	0.8	0.1	-0.2
Mineral and other dietary supplements	0.1	0.1	0.5	0.1	-0.1	0.7	0.3	0.2	0.3	0.1	0.2	0.6	-0.7	0.2	0.4	0.3	0.1	0.2	0.4	-0.1	0.4
Medication: Aspirin	0.1	0.1	0.9	0.2	-0.1	-0.1	0.1	0.1	-0.6	-0.7	0.3	-0.2	-0.9	-0.0	-0.2	-0.0	0.2	-0.0	0.6	0.1	-0.4
Hearing aid user	0.1	0.2	1.0	0.1	0.2	0.6	-0.0	-0.0	0.3	-0.0	0.4	0.5	0.2	0.4	0.6	0.1	0.3	0.4	0.4	1.0	0.1
Mother’s age at death	0.1	0.2	1.1	-0.4	-0.0	0.1	-0.1	-0.3	-0.8	-0.2	-0.0	-0.1	-0.0	-0.5	-0.6	-0.3	0.0	-0.5	-1.1	-0.0	-0.4
Supplements: Fish oil (including cod liver oil)	0.1	0.2	1.0	0.5	-0.3	-0.1	0.0	0.2	-1.0	0.3	0.5	-0.2	0.4	-0.0	-0.2	0.1	0.3	0.4	0.2	0.8	-0.0
Medication: Lisinopril	0.1	0.1	0.6	0.5	0.1	-0.1	-0.2	0.4	0.7	-0.3	0.2	0.6	-0.3	0.1	-0.0	0.1	0.3	0.8	0.3	0.3	0.5
Fractured/broken bones in last 5 years	0.1	0.1	0.5	-0.5	-0.3	0.1	-0.2	-0.1	0.3	-0.2	-0.5	-0.1	-0.0	0.0	0.1	0.3	-0.5	-0.1	0.7	0.7	0.2
Commuting to job workplace: Cycle	0.1	0.1	0.6	-0.5	0.2	-0.1	0.0	-0.5	0.1	-0.1	0.1	0.4	-0.1	-0.4	0.2	-0.2	-0.5	-0.0	-0.8	-0.6	-0.0
Myopia	0.1	0.2	1.3	0.3	0.9	-0.2	0.2	0.1	0.4	0.1	0.3	-0.1	0.5	-0.1	0.1	0.0	0.1	0.5	0.3	1.1	0.3
Bipolar Disorder or Schizophrenia	0.0	0.1	0.4	0.2	-0.0	0.2	-0.1	0.2	0.1	0.3	-0.2	0.2	0.3	-0.6	-0.5	0.2	-0.3	-0.0	0.4	0.3	0.5
Prostate Cancer	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Tanning	0.0	0.4	2.1	-0.1	-0.8	-0.4	-0.7	-0.3	-0.9	-0.6	-0.4	-0.3	-1.4	-0.9	-0.7	-0.5	-0.3	-0.0	-0.8	-0.0	-0.3

Hub : Genes

PSMD5

Models

Trait associations