[Hub]/) : Traits : Pulse rate, automated reading :

chr9:127,035,761-129,422,783

Best TWAS P=1.84e-24 · Best GWAS P=3.36e-25 conditioned to 0.000702

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Artery Tibial PBX3 0.11 0.07 lasso 2 0.06 8.1e-06 5.3 6.1 1.3e-09 -0.53 0.62 0.05 FALSE
2 GTEx Cells Transformed fibroblasts MAPKAP1 0.04 0.03 lasso 3 0.02 6.5e-03 -9.3 -8.5 1.5e-17 0.86 0.07 0.88 FALSE
3 GTEx Cells Transformed fibroblasts PBX3 0.05 0.02 enet 7 0.00 1.4e-01 -9.3 9.4 7.2e-21 -0.91 0.07 0.83 FALSE
4 GTEx Colon Sigmoid PBX3 0.23 0.22 lasso 3 0.16 1.9e-06 5.1 5.4 8.0e-08 -0.45 0.93 0.01 FALSE
5 GTEx Colon Transverse PBX3 0.11 0.01 lasso 3 0.02 5.6e-02 5.9 5.5 5.0e-08 -0.46 0.12 0.29 FALSE
6 GTEx Esophagus Gastroesophageal Junction PBX3 0.21 0.19 lasso 5 0.14 1.0e-05 5.9 5.9 3.3e-09 -0.47 0.47 0.43 FALSE
7 GTEx Esophagus Muscularis PBX3 0.12 0.08 lasso 7 0.09 4.2e-06 5.3 6.6 5.1e-11 -0.55 0.94 0.05 FALSE
8 GTEx Heart Left Ventricle PBX3 0.21 0.22 lasso 4 0.21 3.3e-11 5.1 5.1 2.7e-07 -0.37 1.00 0.00 FALSE
9 GTEx Spleen MAPKAP1 0.30 0.12 lasso 6 0.04 2.7e-02 -9.6 -8.5 1.5e-17 0.79 0.04 0.86 FALSE
10 GTEx Testis PBX3 0.19 0.22 lasso 3 0.20 4.7e-09 4.8 5.6 2.4e-08 -0.44 0.95 0.04 FALSE
11 NTR Blood MAPKAP1 0.03 0.01 blup 441 0.02 2.3e-07 -9.6 -10.2 1.8e-24 0.83 0.19 0.81 TRUE
12 ROSMAP Brain Pre-frontal Cortex SCAI 0.02 0.00 bslmm 316 0.00 3.3e-01 -7.9 -5.4 6.8e-08 0.57 0.04 0.37 FALSE
13 The Cancer Genome Atlas Prostate Adenocarcinoma PBX3 0.03 0.03 blup 65 0.04 5.4e-05 5.1 5.8 6.6e-09 -0.44 0.46 0.51 FALSE