[Hub]/) : Traits : Pulse rate, automated reading :

chr12:24,273,423-27,168,878

Best TWAS P=1.1e-15 · Best GWAS P=1.26e-80 conditioned to 2.2e-74

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Subcutaneous SSPN 0.16 0.06 lasso 7 0.07 1.1e-06 7.2 -5.6 1.8e-08 -0.03 0.00 1.00 FALSE
2 GTEx Adipose Subcutaneous RP11-283G6.5 0.13 0.04 lasso 7 0.02 5.8e-03 7.2 -5.4 6.5e-08 0.00 0.01 0.98 FALSE
3 GTEx Artery Aorta SSPN 0.16 0.00 lasso 2 0.00 5.2e-01 7.2 -7.3 3.3e-13 0.06 0.00 0.99 FALSE
4 GTEx Artery Tibial SSPN 0.17 0.05 enet 13 0.06 1.1e-05 2.4 -5.7 9.7e-09 -0.01 0.01 0.99 FALSE
5 GTEx Artery Tibial RP11-283G6.5 0.13 0.01 enet 15 0.01 2.9e-02 7.2 -6.3 3.7e-10 0.00 0.01 0.93 FALSE
6 GTEx Breast Mammary Tissue SSPN 0.27 0.00 lasso 9 0.02 4.1e-02 7.3 -8.0 1.1e-15 0.00 0.00 0.98 TRUE
7 GTEx Breast Mammary Tissue RP11-283G6.5 0.17 0.02 enet 9 0.02 2.9e-02 7.3 -6.0 1.8e-09 -0.01 0.01 0.91 FALSE
8 GTEx Cells Transformed fibroblasts SSPN 0.14 0.07 enet 15 0.16 3.1e-12 7.2 -5.7 9.6e-09 0.05 0.00 1.00 FALSE
9 GTEx Cells Transformed fibroblasts RP11-283G6.5 0.16 0.05 enet 14 0.15 2.2e-11 7.2 -5.7 1.2e-08 0.05 0.00 1.00 FALSE
10 GTEx Heart Atrial Appendage SSPN 0.27 0.00 enet 4 0.01 1.2e-01 7.2 -7.1 9.4e-13 0.03 0.02 0.79 FALSE
11 GTEx Heart Atrial Appendage RP11-283G6.5 0.27 -0.01 enet 8 0.02 4.5e-02 2.4 -5.6 2.5e-08 -0.01 0.03 0.65 FALSE
12 GTEx Nerve Tibial SSPN 0.18 0.07 lasso 7 0.07 7.3e-06 7.2 -5.8 8.4e-09 0.00 0.00 1.00 FALSE
13 GTEx Testis BCAT1 0.41 0.10 enet 45 0.21 7.2e-10 5.8 -7.2 4.4e-13 0.13 0.80 0.14 TRUE