[Hub]/) : Traits : Pulse rate, automated reading :

chr12:27,234,999-28,643,213

Best TWAS P=3.3e-11 · Best GWAS P=7.67e-11 conditioned to 0.087

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Artery Tibial KLHL42 0.18 0.16 lasso 2 0.14 4.5e-11 6.4 6.4 1.5e-10 1.00 0.00 1.00 FALSE
2 GTEx Artery Tibial RP11-860B13.1 0.09 0.10 lasso 2 0.10 4.8e-08 6.4 6.4 1.2e-10 1.00 0.00 1.00 FALSE
3 The Cancer Genome Atlas Breast Invasive Carcinoma LOC100133893 0.04 0.08 blup 33 0.10 3.6e-19 4.3 5.9 3.1e-09 0.81 0.36 0.64 FALSE
4 The Cancer Genome Atlas Colon Adenocarcinoma LOC100133893 0.07 0.03 blup 33 0.07 7.1e-05 6.3 5.9 3.0e-09 0.85 0.02 0.95 FALSE
5 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma LOC100133893 0.07 0.10 blup 33 0.11 1.2e-12 5.4 5.7 1.3e-08 0.86 0.04 0.96 FALSE
6 The Cancer Genome Atlas Lung Adenocarcinoma LOC100133893 0.09 0.19 lasso 7 0.18 2.8e-20 5.4 5.5 3.6e-08 0.82 0.63 0.37 FALSE
7 The Cancer Genome Atlas Lung Squamous Cell Carcinoma LOC100133893 0.03 0.03 blup 33 0.03 5.4e-04 6.5 5.4 6.4e-08 0.92 0.01 0.99 FALSE
8 The Cancer Genome Atlas Ovarian Serous Cystadenocarcinoma LOC100133893 0.04 0.01 blup 33 0.03 2.1e-03 6.4 6.0 1.6e-09 0.86 0.01 0.81 FALSE
9 The Cancer Genome Atlas Pancreatic Adenocarcinoma LOC100133893 0.06 0.04 blup 33 0.04 1.0e-02 4.3 6.6 3.3e-11 0.84 0.02 0.64 TRUE
10 The Cancer Genome Atlas Stomach Adenocarcinoma KLHDC5 0.06 0.04 blup 55 0.02 6.3e-03 6.3 -5.5 3.0e-08 -0.86 0.01 0.97 FALSE
11 The Cancer Genome Atlas Stomach Adenocarcinoma LOC100133893 0.08 0.09 lasso 2 0.08 2.8e-06 6.4 6.2 6.0e-10 0.99 0.01 0.99 FALSE
12 The Cancer Genome Atlas Thyroid Carcinoma LOC100133893 0.06 0.06 lasso 4 0.06 2.1e-06 5.4 5.4 7.8e-08 0.75 0.26 0.73 FALSE