[Hub]/) : Traits : Pulse rate, automated reading :

chr12:48,605,088-50,364,707

Best TWAS P=1.16e-11 · Best GWAS P=1.61e-08 conditioned to 0.0994

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex TUBA1A 0.08 0.06 lasso 4 0.06 1.8e-07 -5.0 5.3 1.1e-07 -0.68 0.06 0.94 FALSE
2 CommonMind Brain Pre-frontal Cortex TUBA1C 0.41 0.54 lasso 5 0.54 3.0e-77 -5.2 -5.2 1.7e-07 0.71 0.06 0.94 FALSE
3 GTEx Adipose Subcutaneous LMBR1L 0.12 0.09 lasso 6 0.08 1.9e-07 -5.3 6.3 4.0e-10 -0.66 0.02 0.98 FALSE
4 GTEx Adipose Visceral Omentum LMBR1L 0.09 0.03 lasso 6 0.01 7.4e-02 -5.6 5.5 2.9e-08 -0.71 0.02 0.91 FALSE
5 GTEx Artery Aorta RP11-302B13.1 0.16 0.04 enet 13 0.08 2.9e-05 -3.5 6.0 1.5e-09 -0.49 0.04 0.89 FALSE
6 GTEx Artery Aorta RP11-302B13.5 0.13 0.07 lasso 6 0.06 2.0e-04 -5.5 6.8 1.2e-11 -0.65 0.02 0.95 TRUE
7 GTEx Artery Tibial CCDC65 0.14 0.08 enet 39 0.11 7.9e-09 -3.8 -5.6 2.9e-08 0.46 0.83 0.14 FALSE
8 GTEx Brain Cerebellum LMBR1L 0.18 0.15 lasso 1 0.12 1.9e-04 -5.3 5.3 1.2e-07 -0.68 0.02 0.92 FALSE
9 GTEx Esophagus Muscularis TUBA1B 0.08 0.04 lasso 7 0.06 1.9e-04 -5.1 5.2 1.6e-07 -0.75 0.04 0.89 FALSE
10 GTEx Esophagus Muscularis RP11-386G11.10 0.10 0.11 lasso 7 0.10 1.0e-06 -5.1 5.2 1.8e-07 -0.74 0.05 0.94 FALSE
11 GTEx Nerve Tibial RP11-386G11.10 0.07 0.05 lasso 2 0.03 1.8e-03 -5.3 5.3 1.2e-07 -0.68 0.02 0.95 FALSE
12 GTEx Pituitary RP11-386G11.10 0.19 0.11 lasso 5 0.10 1.4e-03 -5.6 5.7 9.3e-09 -0.94 0.03 0.78 FALSE
13 GTEx Skin Sun Exposed Lower leg LMBR1L 0.15 0.10 lasso 3 0.09 3.1e-08 -5.3 5.3 1.1e-07 -0.68 0.02 0.98 FALSE
14 GTEx Spleen LMBR1L 0.30 0.30 enet 11 0.30 2.4e-08 -5.6 5.3 8.8e-08 -0.62 0.01 0.98 FALSE
15 GTEx Testis TUBA1B 0.21 0.28 lasso 9 0.26 7.0e-12 -5.3 5.4 6.7e-08 -0.70 0.03 0.97 FALSE
16 GTEx Testis LMBR1L 0.13 0.11 lasso 3 0.12 4.1e-06 -5.1 5.4 7.8e-08 -0.72 0.02 0.98 FALSE
17 GTEx Testis RP11-386G11.10 0.25 0.33 lasso 9 0.32 1.3e-14 -5.3 5.4 7.6e-08 -0.70 0.03 0.97 FALSE
18 GTEx Thyroid LMBR1L 0.12 0.10 lasso 3 0.10 6.4e-08 -5.3 5.3 1.0e-07 -0.68 0.02 0.98 FALSE
19 The Cancer Genome Atlas Brain Lower Grade Glioma TUBA1C 0.12 0.10 lasso 4 0.10 1.2e-11 -5.1 -5.2 1.5e-07 0.72 0.02 0.98 FALSE