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chr12:48,605,088-50,364,707

Best TWAS P=1.16e-11 · Best GWAS P=1.61e-08 conditioned to 0.0994

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
6	GTEx	Artery Aorta	RP11-302B13.5	0.13	0.07	lasso	6	0.06	2.0e-04	-5.5	6.8	1.2e-11	-0.65	0.02	0.95	TRUE
3	GTEx	Adipose Subcutaneous	LMBR1L	0.12	0.09	lasso	6	0.08	1.9e-07	-5.3	6.3	4.0e-10	-0.66	0.02	0.98	FALSE
5	GTEx	Artery Aorta	RP11-302B13.1	0.16	0.04	enet	13	0.08	2.9e-05	-3.5	6.0	1.5e-09	-0.49	0.04	0.89	FALSE
12	GTEx	Pituitary	RP11-386G11.10	0.19	0.11	lasso	5	0.10	1.4e-03	-5.6	5.7	9.3e-09	-0.94	0.03	0.78	FALSE
4	GTEx	Adipose Visceral Omentum	LMBR1L	0.09	0.03	lasso	6	0.01	7.4e-02	-5.6	5.5	2.9e-08	-0.71	0.02	0.91	FALSE
7	GTEx	Artery Tibial	CCDC65	0.14	0.08	enet	39	0.11	7.9e-09	-3.8	-5.6	2.9e-08	0.46	0.83	0.14	FALSE
15	GTEx	Testis	TUBA1B	0.21	0.28	lasso	9	0.26	7.0e-12	-5.3	5.4	6.7e-08	-0.70	0.03	0.97	FALSE
17	GTEx	Testis	RP11-386G11.10	0.25	0.33	lasso	9	0.32	1.3e-14	-5.3	5.4	7.6e-08	-0.70	0.03	0.97	FALSE
16	GTEx	Testis	LMBR1L	0.13	0.11	lasso	3	0.12	4.1e-06	-5.1	5.4	7.8e-08	-0.72	0.02	0.98	FALSE
14	GTEx	Spleen	LMBR1L	0.30	0.30	enet	11	0.30	2.4e-08	-5.6	5.3	8.8e-08	-0.62	0.01	0.98	FALSE
18	GTEx	Thyroid	LMBR1L	0.12	0.10	lasso	3	0.10	6.4e-08	-5.3	5.3	1.0e-07	-0.68	0.02	0.98	FALSE
1	CommonMind	Brain Pre-frontal Cortex	TUBA1A	0.08	0.06	lasso	4	0.06	1.8e-07	-5.0	5.3	1.1e-07	-0.68	0.06	0.94	FALSE
13	GTEx	Skin Sun Exposed Lower leg	LMBR1L	0.15	0.10	lasso	3	0.09	3.1e-08	-5.3	5.3	1.1e-07	-0.68	0.02	0.98	FALSE
8	GTEx	Brain Cerebellum	LMBR1L	0.18	0.15	lasso	1	0.12	1.9e-04	-5.3	5.3	1.2e-07	-0.68	0.02	0.92	FALSE
11	GTEx	Nerve Tibial	RP11-386G11.10	0.07	0.05	lasso	2	0.03	1.8e-03	-5.3	5.3	1.2e-07	-0.68	0.02	0.95	FALSE
19	The Cancer Genome Atlas	Brain Lower Grade Glioma	TUBA1C	0.12	0.10	lasso	4	0.10	1.2e-11	-5.1	-5.2	1.5e-07	0.72	0.02	0.98	FALSE
9	GTEx	Esophagus Muscularis	TUBA1B	0.08	0.04	lasso	7	0.06	1.9e-04	-5.1	5.2	1.6e-07	-0.75	0.04	0.89	FALSE
2	CommonMind	Brain Pre-frontal Cortex	TUBA1C	0.41	0.54	lasso	5	0.54	3.0e-77	-5.2	-5.2	1.7e-07	0.71	0.06	0.94	FALSE
10	GTEx	Esophagus Muscularis	RP11-386G11.10	0.10	0.11	lasso	7	0.10	1.0e-06	-5.1	5.2	1.8e-07	-0.74	0.05	0.94	FALSE