TWAS hub - TUBA1A

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.079	0.027	5.5e-06	0.061	0.052	0.053	0.052	0.057	5.6e-08	5.7e-07	4.3e-07	6.3e-07	1.8e-07
2	GTEx	Pancreas	0.119	0.056	6.4e-03	-0.007	NA	-0.006	NA	-0.005	9.7e-01	NA	6.9e-01	NA	6.5e-01

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2
Bipolar Disorder (2011)	18.2	17.6	17.7	-4.2	4.2
Comparative body size at age 10	17.8	49.1	72.8	-8.5	5.0
Mean time to correctly identify matches	8.8	16.8	18.2	-4.3	3.9
Pulse rate, automated reading	7.6	24.5	28.2	5.3	-4.6
Reaction Time	6.9	13.2	15.2	-3.9	3.3
Medication for cholesterol	6.8	10.4	13.4	2.7	-3.7
Impedance of leg (right)	6.7	32.3	38.4	6.2	-5.1
Medication: Blood pressure	6.2	11.8	15.7	-2.8	4.0
Handedness (chirality/laterality): Left-handed	5.9	7.1	9.8	3.1	-2.1
Chronic bronchitis/emphysema (father)	5.5	6.5	7.3	2.7	-2.4
Mood swings	5.5	10.0	10.2	3.1	-3.2
Financial difficulties in last 2 years	5.3	7.1	8.0	2.8	-2.5
Worrier / anxious feelings	5.3	10.0	15.2	2.2	-3.9
Schizophrenia vs Biploar Disorder	5.0	6.5	8.1	2.2	-2.8
Cardiovascular Disease	5.0	16.5	18.2	-3.8	4.3
Ever used hormone-replacement therapy (HRT)	4.9	6.3	10.2	-1.5	3.2
Birth weight	4.8	10.3	15.8	-4.0	2.2
Guilty feelings	4.8	7.2	11.4	1.7	-3.4
Bipolar Disorder (2018)	4.5	7.1	11.2	-1.7	3.3
Impedance of arm (right)	4.4	20.5	22.1	4.3	-4.7
Osteoporosis (self-reported)	4.3	5.3	7.6	2.8	-1.7
Impedance of leg (left)	4.1	20.1	24.2	4.9	-4.0
Neuroticism	4.0	9.5	15.1	2.0	-3.9
Worry (Nagel 2018)	3.8	8.0	12.0	2.0	-3.5
Frequency of tenseness / restlessness in last 2 weeks	3.8	5.9	6.5	2.5	-2.3
Hypertension (Self-reported)	3.8	10.7	13.0	-2.9	3.6
Medication: Ramipril	3.7	4.7	6.8	-1.6	2.6
High blood pressure (mother)	3.4	4.7	7.0	-1.6	2.6
Body Mass Index (BMI) (2010)	3.3	4.6	5.3	-2.3	2.0
Systolic Blood Pressure	3.3	16.3	25.8	-2.6	5.1
Financial situation satisfaction	3.3	4.1	4.9	2.2	-1.8
Fractured/broken bones in last 5 years	3.3	4.3	5.8	2.4	-1.7
Neuroticism score	3.2	6.7	9.0	2.1	-3.0
Pulse rate	3.2	5.4	5.8	2.2	-2.4
Supplements: Fish oil (including cod liver oil)	3.2	4.2	5.2	-2.3	1.8
High blood pressure	3.1	8.7	10.4	-2.6	3.2
Neuroticism (Nagel 2018)	2.9	6.7	8.3	2.3	-2.9
Medication: Bendroflumethiazide	2.9	4.4	5.4	-2.3	1.9
Taking other prescription medications	2.8	4.3	7.0	2.6	-1.2
Falls in the last year	2.8	3.8	4.3	-1.8	2.1
Illnesses of mother	2.8	3.4	6.7	0.3	-2.6
Seen doctor (GP) for nerves, anxiety, tension or depression	2.8	4.2	5.9	2.4	-1.6
Supplements: Vitamin C	2.8	3.3	4.0	-1.6	2.0
Mineral and other dietary supplements	2.8	3.8	5.1	2.2	-1.6
Vascular/heart problems diagnosed by doctor	2.8	7.7	10.2	2.3	-3.2
Type 2 Diabetes (T2D) (2012)	2.7	3.1	4.1	-2.0	1.4
Number of children fathered	2.7	3.0	5.0	2.2	-1.0
Bipolar Disorder or Schizophrenia	2.5	6.2	8.9	-1.9	3.0
Hand grip strength (left)	2.5	6.6	8.8	3.0	-2.1
Medication: Levothyroxine sodium	2.5	4.2	4.3	-2.0	2.1
Systolic blood pressure, automated reading	2.4	7.1	12.9	-1.1	3.6
Vitamin and mineral supplements	2.4	3.3	5.5	1.0	-2.4
Leg pain on walking	2.4	3.0	4.4	2.1	-1.2
Impedance of whole body	2.4	12.4	12.9	3.6	-3.4
Multivitamins +/- minerals	2.3	2.9	4.8	-1.0	2.2
Reason for reducing amount of alcohol drunk: Health precaution	2.3	2.7	2.8	-1.6	1.7
Neck or shoulder pain in last month	2.3	3.3	6.2	-0.7	2.5
Suffer from ‘nerves’	2.3	3.6	4.4	1.7	-2.1
Age when periods started (menarche)	2.2	5.4	7.5	2.7	-1.8
Chronic bronchitis/emphysema (mother)	2.2	2.6	4.5	2.1	-0.8
Worry too long after embarrassment	2.2	3.7	7.4	-0.2	-2.7
Irritability	2.2	3.7	5.5	1.4	-2.3
Verbal and Numeric Reasoning (VNR)	2.1	5.1	9.4	-3.1	0.9
High blood pressure (siblings)	2.1	3.0	3.9	-1.4	2.0
Shortness of breath walking on level ground	2.1	2.5	3.7	1.9	-1.1
Alcohol intake frequency.	2.1	4.9	5.4	2.1	-2.3
Ever had prostate specific antigen (PSA) test	2.1	2.4	4.3	-2.1	0.8
Depressed Affect (Nagel 2018)	2.0	4.2	6.1	2.5	-1.5
Age at First Birth	2.0	2.9	4.4	1.2	-2.1
Triglycerides	2.0	3.3	5.0	-2.2	1.3
Hypothyroidism/myxoedema (self-reported)	2.0	3.9	5.4	-2.3	1.5
Ever had hysterectomy (womb removed)	1.9	2.2	4.0	-0.5	2.0
Heel bone mineral density (BMD) T-score, automated (left)	1.8	4.1	4.1	-2.0	2.0
High cholesterol (Self-reported)	1.8	3.2	5.0	-2.2	1.2
Intelligence (Savage-Jansen 2018)	1.7	5.1	9.4	-3.1	0.9
Sensitivity / hurt feelings	1.7	2.9	3.4	1.6	-1.9
Frequency of unenthusiasm / disinterest in last 2 weeks	1.7	2.3	2.7	1.6	-1.4
Hypothyroidism (self reported)	1.6	3.6	4.7	-2.2	1.6
Average weekly spirits intake	1.6	2.0	2.7	-1.6	1.1
Noisy workplace	1.6	2.0	3.6	1.9	-0.5
Diastolic blood pressure, automated reading	1.6	4.8	8.8	-0.9	3.0
Frequency of depressed mood in last 2 weeks	1.5	2.1	2.8	1.7	-1.2
Medication for hormone replacement therapy	1.5	1.7	2.7	-0.8	1.6
Chest pain or discomfort	1.5	2.2	3.7	1.9	-0.9
Medication: Laxatives (e.g. Dulcolax, Senokot)	1.5	1.8	2.6	-1.0	1.6
Breast cancer (self-reported)	1.5	1.7	2.6	1.6	-0.9
Age started oral contraceptive pill	1.5	1.8	2.8	-1.7	0.9
Hearing difficulty/problems: Yes	1.4	2.1	3.6	-0.8	1.9
Relative age of first facial hair	1.4	2.8	4.3	2.1	-1.2
Forced vital capacity (FVC)	1.4	5.4	9.5	1.1	-3.1
Length of working week for main job	1.4	1.5	2.4	-0.8	1.5
Commuting to job workplace: Public transport	1.4	1.6	2.5	-1.6	-0.8
Alcohol drinker status: Previous	1.4	1.6	2.0	1.4	-1.1
Medication: Co-codamol	1.3	1.5	2.8	1.7	-0.3
Medication: Metformin	1.3	1.9	2.6	1.6	-1.1
Townsend deprivation index at recruitment	1.3	1.8	3.4	0.5	-1.8
Qualifications: CSEs or equivalent	1.3	1.7	3.0	1.7	-0.6
Impedance of arm (left)	1.3	5.9	7.8	2.0	-2.8
Fed-up feelings	1.2	2.2	3.9	2.0	-0.7
Nervous feelings	1.2	2.3	2.7	1.6	-1.3
Had other major operations	1.2	1.4	2.4	-0.6	1.6
Serious illness, injury or assault of a close relative in last 2 years	1.2	1.4	1.9	-1.4	0.9
Qualifications: College or University degree	1.2	3.9	6.9	-2.6	-1.0
Commuting to job workplace: Cycle	1.2	1.4	2.7	-1.6	0.5
BMI	1.1	6.6	7.3	-2.7	2.4
Waist Hip Ratio (WHR)	1.1	5.2	7.5	2.7	-1.7
Qualifications: None of the above	1.1	2.4	4.6	2.1	-0.4
Frequency of tiredness / lethargy in last 2 weeks	1.1	1.8	3.3	1.8	-0.5
Angina (self-reported)	1.1	1.4	2.8	-0.0	1.7
Leg fat-free mass (right)	1.1	5.7	8.3	-2.9	1.8
Leg predicted mass (right)	1.1	5.9	8.5	-2.9	1.8
Number of self-reported non-cancer illnesses	1.1	2.0	2.7	-1.1	1.7
Hearing aid user	1.1	1.3	1.6	-1.0	1.2
Mother’s age at death	1.1	1.3	2.3	-1.5	0.6
Ulcerative Colitis (UC)	1.0	1.9	2.1	-1.3	1.5
Neuroticism (2016)	1.0	1.4	2.7	0.3	-1.6
Type 2 Diabetes (T2D) (2018)	1.0	1.8	2.6	1.6	-1.0
Hair/balding pattern: Pattern 3	1.0	1.5	2.8	1.7	-0.5
Forced vital capacity (FVC), Best measure	1.0	3.5	6.9	0.4	-2.6
Qualifications: NVQ or HND or HNC or equivalent	1.0	1.2	2.1	1.4	-0.6
Illnesses of siblings: Diabetes	1.0	1.2	1.3	1.1	-1.2
Friendships satisfaction	1.0	1.2	2.4	0.1	1.6
Back pain experienced in last month	1.0	1.5	1.7	1.1	-1.3
Depression (Nagel 2018)	0.9	1.4	2.1	0.8	-1.4
Fasting Glucose	0.9	1.0	1.7	0.6	-1.3
Lupus	0.9	1.3	2.3	-1.5	0.5
Lung FEV1/FVC ratio	0.9	4.4	7.9	-2.8	1.0
Hair Pigment	0.9	24.5	30.8	5.5	-4.3
Angina	0.9	1.2	2.4	0.2	1.5
Pack years adult smoking proportion	0.9	1.3	2.5	1.6	-0.4
Diverticular disease/diverticulitis (self-reported)	0.9	1.0	1.8	-0.5	1.4
Mouth/teeth dental problems: Dentures	0.9	1.6	2.4	0.9	1.5
Average weekly red wine intake	0.9	1.3	2.5	-1.6	0.1
Long-standing illness, disability or infirmity	0.9	1.4	2.1	1.4	0.8
Medication: Atorvastatin	0.9	1.1	1.1	-1.1	1.0
Pack years of smoking	0.9	1.3	2.5	1.6	-0.3
Ovarian Cancer	0.8	1.0	1.7	-0.6	1.3
Coronary Artery Disease (CAD)	0.8	1.0	1.5	-0.7	1.2
Mean Putamen Volume	0.8	0.9	1.1	1.0	-0.8
Tinnitus: Yes, but not now, but have in the past	0.8	0.8	1.2	0.7	-1.1
Hair/balding pattern: Pattern 2	0.8	1.0	1.4	-0.8	1.2
Medication: Amlodipine	0.8	1.2	1.6	-0.8	1.3
Migraine (self-reported)	0.8	1.0	1.5	1.2	-0.7
Medication: Allopurinol	0.8	1.1	1.8	1.3	-0.7
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.8	1.8	2.4	-1.5	-1.1
Tinnitus: Yes, now most or all of the time	0.8	0.9	1.8	1.4	-0.1
Number of operations (self-reported)	0.8	1.2	2.4	1.6	0.2
Average weekly beer plus cider intake	0.8	1.1	2.0	1.4	-0.5
Myopia	0.8	1.1	1.3	-1.0	1.1
Cholesterol lowering medication	0.8	1.2	1.7	-0.8	1.3
Primary Biliary Cirrhosis	0.7	1.0	1.4	0.7	-1.2
Blood White Count	0.7	5.1	9.4	3.1	-1.0
Maternal smoking around birth	0.7	1.1	1.5	0.8	1.2
Fluid intelligence score	0.7	1.5	2.9	-1.7	0.2
Father’s age at death	0.7	0.9	1.2	-0.7	-1.1
Loud music exposure frequency	0.7	0.8	0.9	-1.0	0.8
Leg fat percentage (right)	0.7	2.6	3.5	1.9	-1.3
Arm fat-free mass (right)	0.7	3.4	4.2	-2.1	1.6
Mouth/teeth dental problems: Loose teeth	0.7	0.8	1.4	0.4	-1.2
Medication: Omeprazole	0.7	0.8	0.9	0.8	-1.0
Schizophrenia (2018)	0.6	1.2	1.3	-1.0	1.1
Schizophrenia (2014)	0.6	1.3	1.5	-1.2	1.1
Chronotype (morning person)	0.6	1.3	1.4	1.2	-1.1
Eye problems/disorders: Diabetes related eye disease	0.6	0.6	1.1	0.4	1.1
Relative age voice broke	0.6	0.9	1.0	0.9	-1.0
Medication: Atenolol	0.6	0.7	1.4	0.4	1.2
Alcohol usually taken with meals	0.6	0.9	1.7	0.4	-1.3
Heel bone mineral density (BMD) T-score, automated (right)	0.6	1.3	1.4	-1.1	1.2
Time employed in main current job	0.6	0.7	1.5	-0.1	-1.2
Forced expiratory volume in 1-second (FEV1), Best measure	0.6	1.8	3.1	-0.6	-1.8
Seen a psychiatrist for nerves, anxiety, tension or depression	0.6	0.8	1.5	1.2	-0.1
Arm predicted mass (right)	0.6	3.1	3.9	-2.0	1.5
Commuting to job workplace: Car/motor vehicle	0.6	0.7	1.4	1.2	0.3
Smoking status: Current	0.6	1.0	1.1	1.1	-0.9
Ever taken oral contraceptive pill	0.6	0.7	1.3	1.1	-0.3
Pain experienced in last month	0.6	0.9	1.9	-0.0	-1.4
Alzheimer’s Disease (in father)	0.5	0.6	0.8	-0.9	0.5
Irritable Bowel Disease (IBD)	0.5	1.3	1.5	-1.2	1.0
Major Depression (MDD)	0.5	0.6	0.9	-0.6	-1.0
Blood Platelet Count	0.5	5.4	7.1	2.7	-1.9
Heel T-Score	0.5	4.3	4.9	-2.2	1.9
Lung FVC	0.5	2.4	4.6	-0.5	-2.1
Supplements: Zinc	0.5	0.5	1.0	-1.0	0.2
Diabetes (mother)	0.5	0.6	1.1	-0.3	1.0
Leg fat-free mass (left)	0.5	2.5	4.0	-2.0	1.0
Current tobacco smoking	0.5	0.9	1.5	1.2	-0.5
Bilateral oophorectomy (both ovaries removed)	0.5	0.5	0.7	0.8	-0.6
Hayfever, allergic rhinitis or eczema	0.5	1.2	1.2	-1.1	1.1
Leg predicted mass (left)	0.5	2.5	4.1	-2.0	1.0
Had menopause	0.5	0.7	1.3	-0.2	1.1
Diabetes (self-reported)	0.5	0.7	1.4	1.2	-0.2
Forced expiratory volume in 1-second (FEV1)	0.5	1.8	3.5	0.1	-1.9
Qualifications: A levels/AS levels or equivalent	0.5	1.2	1.5	-0.9	-1.2
Depression (self-reported)	0.5	0.6	0.8	-0.6	0.9
Breastfed as a baby	0.5	0.7	1.0	0.6	-1.0
Qualifications: O levels/GCSEs or equivalent	0.5	0.8	1.6	-1.3	-0.3
Mouth/teeth dental problems: Bleeding gums	0.5	0.7	1.0	-1.0	0.6
Family relationship satisfaction	0.5	0.6	0.8	-0.7	0.9
Eye problems/disorders: Glaucoma	0.5	0.6	1.0	-0.4	1.0
Illnesses of father: High blood pressure	0.5	0.6	1.1	-1.1	0.2
Unable to work because of sickness or disability	0.5	0.7	1.2	1.1	-0.4
HbA1C	0.4	0.5	1.0	-0.1	-1.0
HDL Cholesterol	0.4	0.7	1.0	1.0	-0.6
Height	0.4	6.8	8.0	2.3	-2.8
Respiratory disease	0.4	0.8	1.5	1.2	0.4
Number of treatments/medications taken	0.4	0.7	1.3	-0.2	1.1
Supplements: Glucosamine	0.4	0.5	0.6	-0.8	0.7
Body mass index (BMI)	0.4	1.9	2.1	-1.3	1.4
Ever unenthusiastic/disinterested for a whole week	0.4	0.5	0.8	-0.5	0.9
Alcohol intake versus 10 years previously	0.4	0.6	1.2	1.1	-0.2
Standing height	0.4	3.6	5.8	1.2	-2.4
Hair/balding pattern: Pattern 4	0.4	1.1	1.9	-1.4	0.5
Pulse wave reflection index	0.4	0.5	0.5	-0.7	0.7
Exposure to tobacco smoke outside home	0.4	0.6	0.9	-1.0	0.5
Wheeze or whistling in the chest in last year	0.4	0.7	1.2	1.1	0.5
Overall health rating	0.4	0.9	1.9	1.4	0.2
Knee pain experienced in last month	0.4	0.7	1.2	0.3	1.1
Smoking status: Previous	0.4	0.5	1.1	-0.2	1.0
Forced expiratory volume in 1-second (FEV1), predicted	0.4	0.8	0.8	0.9	-0.9
Osteoarthritis (self-reported)	0.4	0.6	1.1	1.1	0.1
Whole body water mass	0.4	2.3	3.7	-1.9	0.9
Average weekly champagne plus white wine intake	0.4	0.6	0.9	-0.6	-0.9
Ever smoked	0.4	0.7	1.0	1.0	-0.7
Supplements: Calcium	0.4	0.5	0.8	0.9	-0.4
Blood Eosinophil Count	0.3	2.5	4.6	2.1	-0.6
Blood Red Count	0.3	2.7	4.3	2.1	-1.1
Allergy or Eczema	0.3	0.7	0.9	-0.7	1.0
Other serious medical condition/disability diagnosed by doctor	0.3	0.3	0.7	0.1	0.8
Hand grip strength (right)	0.3	0.9	1.4	1.2	-0.7
Average weekly fortified wine intake	0.3	0.4	0.6	-0.3	-0.8
Sitting height	0.3	1.8	2.5	1.1	-1.6
Heart attack	0.3	0.4	0.8	-0.2	0.9
Allergy	0.3	0.8	1.0	0.7	-1.0
Illnesses of siblings	0.3	0.4	0.6	0.4	-0.8
Number of live births	0.3	0.4	0.7	0.3	0.8
Tense / ‘highly strung’	0.3	0.6	0.8	0.5	-0.9
Ever highly irritable/argumentative for 2 days	0.3	0.3	0.6	-0.8	-0.2
Heart disease (mother)	0.3	0.3	0.6	-0.1	0.8
Had major operations	0.3	0.3	0.3	0.6	0.6
Age at last live birth	0.3	0.4	0.5	-0.5	-0.7
Whole body fat-free mass	0.3	1.8	3.1	-1.8	0.8
Ever had stillbirth, spontaneous miscarriage or termination	0.3	0.3	0.5	-0.2	0.7
Qualifications: nursing, teaching	0.3	0.5	1.1	-1.0	-0.1
Mouth/teeth dental problems: Mouth ulcers	0.3	0.4	0.8	-0.9	-0.1
Medication: Gliclazide	0.3	0.4	0.5	0.5	-0.7
Pain type(s) experienced in last month: Hip pain	0.3	0.4	0.8	-0.0	0.9
Basal metabolic rate	0.3	1.4	2.4	-1.6	0.7
Heart attack/myocardial infarction (self-reported)	0.3	0.4	0.7	-0.0	0.9
Heart disease (siblings)	0.3	0.3	0.4	0.6	-0.6
Alzheimer’s Disease (in mother)	0.2	0.3	0.3	0.6	0.4
Smoking Status	0.2	0.4	0.6	0.4	0.8
Tanning	0.2	1.9	2.4	-1.2	1.6
Severe depression (siblings)	0.2	0.2	0.3	0.6	-0.4
Number of incorrect matches in round	0.2	0.4	0.7	-0.2	-0.9
Hearing difficulty/problems with background noise	0.2	0.3	0.5	0.7	0.4
Mouth/teeth dental problems	0.2	0.4	0.4	-0.6	-0.6
Arm fat percentage (right)	0.2	0.8	1.0	0.8	-1.0
Medication: Ibuprofen (e.g. Nurofen)	0.2	0.3	0.5	0.7	-0.2
Prospective memory result	0.2	0.2	0.5	-0.1	-0.7
Lung cancer (father)	0.2	0.2	0.3	0.4	0.5
Blood clot in the leg (DVT)	0.2	0.2	0.3	-0.4	0.6
Headache pain in last month	0.2	0.4	0.6	0.8	0.3
Gout (self-reported)	0.2	0.2	0.4	0.6	-0.2
Body fat percentage	0.2	0.9	0.9	0.9	-1.0
Age at first live birth	0.2	0.4	0.7	-0.3	-0.8
Emphysema/chronic bronchitis	0.2	0.2	0.3	0.6	0.2
Medication for pain relief, constipation, heartburn	0.2	0.4	0.7	-0.8	0.4
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.2	0.3	0.4	-0.7	-0.3
Number of full sisters	0.2	0.3	0.6	0.7	-0.0
Illness, injury, bereavement, stress in last 2 years	0.2	0.2	0.4	-0.6	0.3
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.2	0.2	0.4	-0.0	-0.6
Loneliness, isolation	0.2	0.3	0.4	0.7	0.3
Diabetes diagnosed by doctor	0.2	0.4	0.8	0.9	-0.0
Asthma (self-reported)	0.2	0.4	0.7	0.8	0.0
Miserableness	0.2	0.4	0.7	0.8	-0.4
Medication: Lisinopril	0.2	0.3	0.5	-0.3	0.7
Arm fat-free mass (left)	0.2	1.0	1.3	-1.1	0.8
Deep venous thrombosis (DVT) (self-reported)	0.2	0.3	0.4	-0.4	0.6
Arm predicted mass (left)	0.2	0.8	1.1	-1.0	0.7
Alzheimer’s Disease (including proxy)	0.1	0.1	0.3	-0.1	0.5
Crohns Disease (2012)	0.1	0.2	0.3	-0.5	0.2
LDL Cholesterol	0.1	0.1	0.2	-0.5	-0.1
Rheumatoid Arthritis	0.1	0.1	0.1	-0.0	-0.4
Trunk fat percentage	0.1	0.3	0.4	0.4	-0.7
Serious illness, injury or assault to yourself	0.1	0.1	0.2	0.1	-0.4
Stomach or abdominal pain in last month	0.1	0.1	0.1	0.1	0.3
Trunk fat mass	0.1	0.2	0.4	0.2	-0.6
Past tobacco smoking	0.1	0.1	0.3	-0.5	-0.1
Pain all over the body in last month	0.1	0.1	0.1	-0.3	0.3
Medication: Simvastatin	0.1	0.1	0.2	0.4	-0.1
Weight	0.1	0.4	0.7	-0.8	0.3
Trunk fat-free mass	0.1	0.7	1.3	-1.1	0.2
Happiness	0.1	0.1	0.3	0.5	0.0
Asthma	0.1	0.3	0.5	0.7	0.4
Medication: Cholesterol lowering	0.1	0.2	0.4	-0.1	0.6
Pulse wave Arterial Stiffness index	0.1	0.1	0.1	0.3	0.3
Trunk predicted mass	0.1	0.7	1.4	-1.2	0.2
Medication: Paracetamol	0.1	0.1	0.2	-0.5	0.2
Medication: Ventolin 100micrograms inhaler	0.1	0.1	0.2	0.4	-0.3
Pulse wave peak to peak time	0.1	0.2	0.2	-0.4	-0.4
Eye problems/disorders: None of the above	0.1	0.2	0.3	-0.5	-0.1
Medication: Ibuprofen	0.1	0.1	0.2	0.4	0.0
Medication: Seretide 50 evohaler	0.1	0.1	0.2	-0.2	0.5
Leg fat mass (right)	0.1	0.5	0.7	0.8	-0.5
Comparative height size at age 10	0.1	0.4	0.4	-0.6	-0.6
Medication: Aspirin	0.1	0.2	0.3	0.5	0.3
Eye problems/disorders: Cataract	0.1	0.1	0.2	-0.4	0.3
Medication: Aspirin	0.1	0.1	0.1	0.4	0.1
Arm fat mass (left)	0.1	0.4	0.6	-0.8	0.5
Leg fat percentage (left)	0.1	0.5	0.8	0.9	-0.4
Risk taking	0.1	0.1	0.2	-0.2	0.5
Medication: Omeprazole (e.g. Zanprol)	0.1	0.2	0.3	-0.1	-0.6
Basal cell carcinoma (self-reported)	0.1	0.1	0.2	-0.5	-0.2
Crohns Disease (2017)	0.0	0.1	0.2	-0.5	-0.0
Breast Cancer	0.0	0.0	0.0	0.0	0.0
Prostate Cancer	0.0	0.0	0.0	0.0	0.0
Ulcerative Colitis	0.0	0.1	0.1	-0.4	-0.0
Diabetes (father)	0.0	0.0	0.1	0.1	-0.2
Waist circumference	0.0	0.2	0.3	0.5	-0.3
Hayfever/allergic rhinitis (self-reported)	0.0	0.0	0.0	-0.2	0.1
Hip circumference	0.0	0.1	0.2	-0.5	0.0
Medication: Lansoprazole	0.0	0.1	0.1	0.2	-0.2
Arm fat mass (right)	0.0	0.0	0.0	-0.1	-0.1
Exposure to tobacco smoke at home	0.0	0.0	0.1	-0.1	0.2
Birth weight of first child	0.0	0.0	0.0	-0.1	-0.0
Peak expiratory flow (PEF)	0.0	0.1	0.1	-0.4	0.1
Medication for cholesterol, blood pressure or diabetes	0.0	0.1	0.1	0.1	-0.4
Glaucoma (self-reported)	0.0	0.0	0.0	0.0	0.0
Number of full brothers	0.0	0.0	0.0	0.1	0.2
Health satisfaction	0.0	0.0	0.0	0.0	-0.1
Medication: Blood pressure	0.0	0.0	0.0	-0.1	0.0
Whole body fat mass	0.0	0.1	0.1	0.1	-0.4
Illnesses of father: Heart disease	0.0	0.0	0.0	-0.1	-0.2
Arm fat percentage (left)	0.0	0.1	0.1	-0.3	-0.1
Ever had bowel cancer screening	0.0	0.0	0.0	-0.0	-0.1
Commuting to job workplace: Walk	0.0	0.0	0.0	0.1	0.2
Illnesses of father: None of the above (group 1)	0.0	0.0	0.0	-0.2	0.1
Wears glasses or contact lenses	0.0	0.0	0.0	0.2	0.1
Medication: Paracetamol	0.0	0.0	0.1	0.2	-0.3
Alcohol drinker status: Never	0.0	0.0	0.1	0.1	-0.2
Ever depressed for a whole week	0.0	0.0	0.0	0.2	-0.0
Leg fat mass (left)	0.0	0.0	0.1	0.2	-0.1

Hub : Genes

TUBA1A

Models

Trait associations