Best TWAS P=4.51e-17 · Best GWAS P=6.99e-19 conditioned to 0.000942
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Stomach | CPNE8 | 0.11 | 0.08 | lasso | 4 | 0.01 | 0.102 | 7.9 | -7.8 | 8.0e-15 | -0.72 | 0.05 | 0.48 | FALSE |
| 2 | ROSMAP | Brain Pre-frontal Cortex | ALG10B | 0.03 | 0.00 | blup | 201 | 0.02 | 0.004 | 7.8 | 5.4 | 5.2e-08 | 0.71 | 0.05 | 0.51 | FALSE |
| 3 | The Cancer Genome Atlas | Breast Invasive Carcinoma | ALG10B | 0.01 | 0.01 | blup | 30 | 0.00 | 0.039 | 8.3 | 8.4 | 4.5e-17 | 0.85 | 0.01 | 0.90 | TRUE |
| 4 | The Cancer Genome Atlas | Soft Tissue Sarcoma | ALG10B | 0.05 | 0.03 | lasso | 3 | 0.02 | 0.013 | -7.0 | 6.9 | 5.2e-12 | 0.72 | 0.02 | 0.61 | FALSE |