Hub : Genes

TUBA1C

Models

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.4060	0.0470	0.0e+00	0.537	0.483	0.532	0.531	0.536	2.0e-77	1.0e-66	2.0e-76	3.0e-76	3.0e-77
2	GTEx	Skin Sun Exposed Lower leg	0.0670	0.0310	1.9e-03	0.031	NA	0.049	NA	0.054	1.3e-03	NA	6.1e-05	NA	2.7e-05
3	YFS	Blood	0.0195	0.0112	1.8e-02	0.006	0.004	0.015	0.009	0.013	2.5e-03	1.0e-02	1.0e-05	5.8e-04	3.8e-05
4	TCGA	Brain Lower Grade Glioma	0.1240	0.0476	2.6e-09	0.099	0.088	0.099	NA	0.102	2.3e-11	3.5e-10	2.8e-11	NA	1.2e-11
5	TCGA	Lung Adenocarcinoma	0.0348	0.0191	6.9e-04	0.040	0.024	0.025	NA	0.033	1.7e-05	7.1e-04	6.0e-04	NA	7.7e-05
6	TCGA	Prostate Adenocarcinoma	0.0446	0.0230	3.1e-05	0.024	0.043	0.037	NA	0.035	1.5e-03	2.3e-05	9.4e-05	NA	1.3e-04
7	TCGA	Thyroid Carcinoma	0.1190	0.0550	1.1e-03	0.003	-0.002	-0.003	NA	0.043	1.7e-01	6.2e-01	9.6e-01	NA	4.7e-05
8	TCGA	Uterine Corpus Endometrial Carcinoma	0.1280	0.0690	7.5e-03	0.041	0.084	0.068	NA	0.006	2.6e-02	2.5e-03	5.9e-03	NA	2.1e-01

Trait associations

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8
Bipolar Disorder (2018)	1.1	1.7	3.1	1.8	-1.4	1.4	1.7	-0.8	1.5	0.5	0.6
Bipolar Disorder or Schizophrenia	0.6	1.4	2.9	1.7	-1.1	0.9	1.6	-1.2	1.1	-0.5	0.5
Depressed Affect (Nagel 2018)	1.8	3.7	8.1	-2.4	2.1	0.7	-2.3	1.9	-2.9	0.8	1.3
Depression (Nagel 2018)	0.8	1.2	2.9	-0.9	0.8	0.9	-1.7	0.6	-1.4	-1.2	0.8
Intelligence (Savage-Jansen 2018)	2.0	6.0	9.4	3.1	-3.0	3.0	3.0	-1.9	2.7	0.6	-0.5
Neuroticism (Nagel 2018)	0.8	1.9	4.7	-2.0	1.3	0.4	-2.1	0.5	-2.2	-0.2	-0.1
Schizophrenia (2018)	0.2	0.4	0.9	0.8	-0.3	0.0	0.7	-1.0	0.2	-0.9	0.2
Schizophrenia vs Biploar Disorder	2.2	3.0	6.2	-2.4	1.1	-2.5	-2.5	0.8	-1.3	-0.5	-1.4
Worry (Nagel 2018)	0.8	1.8	3.8	-1.8	1.4	-0.7	-1.7	1.1	-1.9	0.0	-0.6
Alzheimer’s Disease (in mother)	0.5	0.6	3.4	0.1	0.6	0.5	0.3	-0.6	-0.4	-0.6	1.9
Alzheimer’s Disease (in father)	1.1	1.2	2.9	0.9	-1.3	-0.8	0.9	-0.4	1.3	0.7	-1.7
Alzheimer’s Disease (including proxy)	0.2	0.3	0.6	0.6	-0.6	0.0	0.6	-0.7	0.8	-0.4	-0.2
Crohns Disease (2017)	0.2	0.3	0.8	0.3	-0.9	0.7	0.3	0.2	0.7	0.7	-0.5
Irritable Bowel Disease (IBD)	0.5	1.3	5.6	0.9	-1.3	2.4	0.9	-0.1	0.9	0.6	0.2
Ulcerative Colitis (UC)	0.9	1.8	8.7	1.0	-1.2	3.0	1.1	-0.2	0.5	0.6	1.2
Major Depression (MDD)	0.3	0.4	1.1	0.2	-0.5	1.1	0.1	-0.2	0.3	-0.8	-1.0
Reaction Time	6.0	11.4	23.3	3.9	-4.2	0.6	3.9	-3.6	4.8	1.7	-1.8
Verbal and Numeric Reasoning (VNR)	2.5	6.1	10.8	2.8	-3.3	3.2	2.6	-1.8	2.6	1.1	-1.3
Breast Cancer	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Ovarian Cancer	0.2	0.2	0.4	0.6	-0.4	0.1	0.4	0.3	0.6	0.6	-0.6
Prostate Cancer	1.8	2.6	20.4	0.0	0.0	0.0	0.0	0.0	4.5	0.0	0.0
Age at First Birth	0.4	0.5	1.2	-0.9	0.4	-1.0	-1.1	0.5	-0.8	0.2	0.0
Bipolar Disorder (2011)	4.7	4.5	17.6	4.2	-2.7	3.4	0.0	0.0	0.0	0.0	0.0
Body Mass Index (BMI) (2010)	2.7	3.8	8.8	2.0	-2.1	3.0	1.9	-1.9	2.3	-0.4	0.1
Coronary Artery Disease (CAD)	0.5	0.6	1.7	0.5	-0.9	1.0	0.6	-1.3	0.7	0.6	0.0
Crohns Disease (2012)	0.3	0.4	1.5	0.4	-0.1	0.4	0.4	1.2	0.1	1.1	0.3
Mean Putamen Volume	0.6	0.7	1.5	-1.1	0.4	1.2	-0.9	0.5	-1.2	0.2	0.7
Fasting Glucose	0.4	0.5	2.3	-0.6	0.5	-1.5	-0.5	0.2	-0.8	0.1	-0.4
HbA1C	3.0	3.3	7.3	-2.7	2.1	0.6	-2.6	1.4	-2.1	0.4	1.0
HDL Cholesterol	0.4	0.7	2.1	-0.6	0.6	-0.8	-0.5	0.5	-1.4	-0.9	0.8
LDL Cholesterol	0.3	0.5	1.2	0.1	-0.4	-1.0	-0.1	-0.9	1.1	0.2	-1.1
Lupus	0.6	1.0	2.5	1.6	-0.9	-0.1	1.6	-1.1	0.7	-0.1	0.7
Neuroticism (2016)	0.3	0.4	0.9	-0.6	0.4	1.0	-0.8	-0.0	-0.7	-0.5	-0.8
Primary Biliary Cirrhosis	0.4	0.6	1.8	-1.3	0.2	-0.4	-1.2	0.2	-0.3	0.7	-0.8
Rheumatoid Arthritis	0.8	1.1	2.4	0.3	1.4	-0.7	0.3	1.6	-0.9	1.2	1.1
Schizophrenia (2014)	0.2	0.4	1.1	0.9	0.5	-0.3	0.8	-0.5	0.2	-1.0	-0.2
Triglycerides	1.3	2.2	4.0	1.9	-1.5	2.0	1.9	-1.0	1.5	0.4	0.8
Type 2 Diabetes (T2D) (2012)	1.6	1.9	5.9	2.4	-1.0	0.7	1.8	-0.5	0.7	-0.7	1.7
Ulcerative Colitis	0.5	0.7	3.7	-0.1	0.2	1.9	-0.1	0.7	-0.7	0.7	0.7
Blood Eosinophil Count	0.3	2.2	5.1	-1.8	0.4	-0.9	-1.8	0.8	-1.1	2.2	-1.8
Blood Platelet Count	0.8	9.5	44.0	-2.2	-1.7	6.6	-2.3	2.6	-1.2	0.8	3.1
Blood Red Count	0.2	2.2	6.0	-2.1	-0.0	-0.8	-2.4	-1.7	-0.4	-1.5	-1.1
Blood White Count	0.8	5.8	22.8	-2.8	2.0	-4.8	-2.8	0.2	-1.7	0.8	-0.8
Heel T-Score	1.2	9.4	31.2	1.4	-1.8	-1.1	1.0	-5.6	4.2	0.0	-4.4
BMI	1.2	7.1	16.1	2.2	-3.3	1.5	2.0	-4.0	3.7	-0.5	-2.1
Height	0.3	5.0	9.3	-2.7	2.7	-3.0	-2.9	-0.3	-1.4	0.4	-2.5
Waist Hip Ratio (WHR)	0.9	3.8	9.2	-2.3	1.8	-1.1	-2.2	2.4	-3.0	0.2	1.0
Systolic Blood Pressure	0.5	2.7	4.8	2.0	-2.0	1.4	2.2	-1.0	1.5	1.7	1.0
Smoking Status	0.6	1.3	3.6	-0.5	0.5	-1.9	-0.2	0.4	-0.7	1.6	1.9
Allergy or Eczema	0.2	0.5	2.1	0.3	-0.7	0.6	0.4	-0.1	0.7	0.4	-1.4
Cardiovascular Disease	1.8	6.0	11.4	3.4	-2.9	1.0	3.4	-2.4	2.9	0.3	0.9
Hypothyroidism (self reported)	0.7	1.7	3.5	1.9	-1.8	0.8	1.6	-0.5	1.1	1.3	-0.4
Respiratory disease	0.8	1.7	3.9	-1.2	1.4	-0.5	-1.1	1.9	-2.0	0.6	0.7
Type 2 Diabetes (T2D) (2018)	1.5	2.7	5.7	-1.5	2.0	-1.5	-1.5	1.7	-2.4	1.4	0.5
Lung FEV1/FVC ratio	1.4	7.2	18.1	2.8	-4.3	3.3	2.5	-2.1	3.1	-0.1	0.4
Lung FVC	0.7	3.5	7.9	0.9	-2.3	0.2	1.0	-2.5	2.8	-1.3	-2.2
Neuroticism	0.9	2.1	4.9	-2.0	1.1	-0.1	-1.9	1.5	-2.2	0.8	-0.2
Chronotype (morning person)	0.5	1.1	2.4	-0.8	1.3	-1.5	-0.6	1.2	-1.3	0.6	0.6
Hair Pigment	0.5	13.9	29.3	-5.4	3.7	-3.4	-5.3	2.8	-4.5	-0.9	-0.5
Tanning	0.0	0.5	1.5	1.0	-0.3	-0.0	0.7	-0.7	-0.0	-1.2	0.7
Hand grip strength (left)	1.9	4.9	11.4	-3.1	1.6	-0.9	-3.4	-0.9	-0.8	-3.2	-1.8
Number of treatments/medications taken	0.4	0.7	5.1	-0.3	0.2	-0.1	-0.4	0.3	0.2	0.4	-2.2
Average weekly spirits intake	1.3	1.7	3.6	1.8	-1.1	1.2	1.8	-0.5	1.9	-0.5	-0.2
Sensitivity / hurt feelings	1.2	2.0	5.0	-1.3	1.5	-1.9	-1.3	1.2	-2.2	0.3	0.9
Frequency of depressed mood in last 2 weeks	2.0	2.8	6.3	-1.8	2.1	0.4	-1.9	1.8	-2.5	-0.4	1.0
Hearing difficulty/problems: Yes	0.8	1.3	3.7	1.0	-1.9	0.4	0.9	-1.3	0.9	-0.5	1.3
Relative age of first facial hair	1.5	3.1	9.0	-1.6	2.1	-0.1	-1.8	2.1	-3.0	0.3	0.9
Other serious medical condition/disability diagnosed by doctor	1.0	1.2	4.2	0.1	0.5	-0.1	-0.0	1.8	-1.4	2.1	-0.3
Ever used hormone-replacement therapy (HRT)	0.9	1.2	2.2	1.5	-1.3	0.2	1.3	-0.0	0.4	1.5	1.2
Ever had hysterectomy (womb removed)	1.8	2.0	10.0	1.2	0.2	0.5	1.4	0.7	-0.7	1.3	3.2
Systolic blood pressure, automated reading	0.1	0.4	1.4	0.8	0.0	0.0	0.9	-0.0	0.3	1.2	0.2
Eye problems/disorders: Diabetes related eye disease	0.5	0.5	1.6	0.0	0.6	0.6	-0.2	1.1	-1.2	0.6	0.5
Angina	0.9	1.2	4.5	-0.3	1.0	-0.7	-0.2	1.2	-1.2	2.1	0.9
Medication for hormone replacement therapy	0.5	0.6	2.4	0.4	-0.1	-1.6	0.4	0.1	-0.1	1.4	-0.4
Vitamin and mineral supplements	0.6	0.8	1.5	-1.2	0.1	-0.9	-1.2	0.5	-0.9	1.2	0.1
Supplements: Zinc	0.8	0.9	2.1	0.6	-0.6	-0.2	0.6	-0.9	1.1	-1.5	-1.3
Medication: Co-codamol	1.3	1.5	3.1	-1.4	1.8	-0.7	-1.4	1.5	-1.5	0.4	-0.3
Medication: Metformin	1.1	1.5	2.9	-1.7	1.3	-1.0	-1.7	1.1	-1.5	0.8	-0.3
Diabetes (father)	0.1	0.1	0.2	-0.3	-0.1	-0.3	-0.2	0.3	-0.3	0.3	0.4
Diabetes (mother)	1.0	1.3	3.6	0.5	-1.7	1.9	0.4	-1.6	1.1	0.1	0.2
Severe depression (siblings)	0.4	0.5	0.9	-0.5	0.7	-1.0	-0.6	0.8	-0.9	0.3	0.1
Pack years adult smoking proportion	2.4	3.7	9.4	-1.9	1.8	-3.1	-2.2	1.4	-2.4	-0.5	-0.5
Impedance of leg (right)	3.0	14.8	32.4	-5.7	4.2	-3.4	-5.5	2.5	-4.1	-1.8	0.5
Leg fat-free mass (left)	0.4	2.1	5.2	1.5	-0.8	0.1	1.4	-1.4	1.8	1.3	-2.3
Trunk fat percentage	0.4	1.4	4.7	-0.5	0.5	-2.2	-0.3	-1.2	0.7	-0.4	-2.0
Hand grip strength (right)	0.5	1.4	2.6	-1.5	0.5	-0.7	-1.6	-1.2	0.3	-1.6	-1.3
Townsend deprivation index at recruitment	0.7	1.1	4.2	-0.7	-0.3	-1.3	-0.7	-0.6	0.4	1.0	-2.0
Current tobacco smoking	1.2	2.0	4.7	-1.3	1.5	-2.2	-1.5	1.1	-1.7	-0.4	0.6
Average weekly fortified wine intake	0.2	0.3	0.7	-0.2	0.8	0.1	-0.5	0.8	-0.6	0.4	-0.6
Maternal smoking around birth	0.7	1.0	3.9	-0.9	0.4	-0.5	-0.7	0.1	-1.1	-2.0	1.0
Fed-up feelings	1.4	2.6	5.6	-1.7	1.5	1.2	-1.6	1.5	-2.4	0.7	1.7
Frequency of unenthusiasm / disinterest in last 2 weeks	1.6	2.1	4.3	-1.6	2.1	-0.6	-1.7	1.1	-2.0	-1.0	0.9
Relative age voice broke	1.3	2.0	4.7	-0.9	1.3	0.2	-1.0	1.5	-2.2	0.8	2.1
Taking other prescription medications	3.8	5.9	11.6	-2.8	2.5	-0.7	-2.9	3.4	-2.9	2.2	-0.5
Age when periods started (menarche)	3.2	7.8	16.8	-1.9	4.1	-2.0	-1.7	3.9	-3.9	0.9	1.8
Bilateral oophorectomy (both ovaries removed)	0.6	0.7	2.3	-0.8	0.3	-0.1	-0.9	0.7	-1.5	-0.2	1.0
Heel bone mineral density (BMD) T-score, automated (left)	1.8	4.2	9.7	2.0	-2.4	0.4	2.1	-3.1	2.9	0.8	0.1
Tinnitus: Yes, but not now, but have in the past	0.7	0.7	1.4	-0.9	1.0	-0.5	-0.8	0.7	-0.2	1.2	-1.2
Qualifications: CSEs or equivalent	1.5	2.0	3.5	-1.5	1.5	-0.7	-1.6	1.4	-1.9	1.3	1.1
Serious illness, injury or assault to yourself	1.2	1.5	4.6	-0.7	1.5	-0.5	-0.9	2.1	-1.9	0.4	-0.3
High blood pressure	0.8	2.3	5.2	2.3	-1.3	1.9	2.3	-0.7	1.1	0.6	1.0
Hayfever, allergic rhinitis or eczema	0.6	1.4	2.5	0.7	-1.5	1.4	0.7	-0.9	1.4	-0.7	-1.6
Multivitamins +/- minerals	0.8	1.1	2.2	1.1	-0.5	0.7	1.2	-1.0	1.5	-1.1	-0.8
Stomach or abdominal pain in last month	0.5	0.6	1.8	-0.4	1.0	-0.5	-0.6	0.1	0.0	-1.3	-1.1
Supplements: Glucosamine	1.7	2.2	6.2	0.5	-2.5	1.2	0.6	-1.0	1.9	0.5	-2.1
Diverticular disease/diverticulitis (self-reported)	0.9	1.0	4.4	0.5	-0.5	1.0	0.4	1.2	-0.7	0.5	2.1
Medication: Atenolol	0.1	0.1	0.6	-0.0	-0.1	0.1	0.1	-0.0	-0.2	0.6	0.8
Medication: Levothyroxine sodium	1.8	3.1	8.6	2.1	-1.8	1.6	2.0	0.2	1.0	2.9	0.8
Sitting height	0.2	1.6	5.7	-0.9	0.5	-1.4	-0.8	-0.6	0.6	1.7	-2.4
Chronic bronchitis/emphysema (father)	4.9	5.7	10.2	-3.0	3.2	-1.6	-3.1	2.1	-3.0	-0.7	-0.3
High blood pressure (mother)	0.7	1.0	2.5	1.2	-1.0	1.6	1.1	-0.2	0.8	1.2	0.4
Body mass index (BMI)	0.3	1.3	3.0	0.9	-1.1	0.1	0.9	-1.6	1.5	-0.2	-1.7
Impedance of leg (left)	1.9	9.2	19.7	-4.4	3.2	-3.0	-4.4	2.1	-3.2	-0.8	0.5
Leg predicted mass (left)	0.4	2.1	5.2	1.5	-0.8	0.0	1.5	-1.4	1.7	1.3	-2.3
Trunk fat mass	0.4	1.8	6.5	-0.3	0.3	-2.1	-0.2	-1.4	0.9	-0.0	-2.5
Waist circumference	0.2	0.6	1.5	-0.8	0.4	-1.2	-0.8	-0.7	-0.2	0.2	-0.9
Number of incorrect matches in round	0.4	0.7	2.1	-0.0	0.8	-1.4	0.1	0.1	0.7	0.7	-1.4
Past tobacco smoking	0.6	1.1	3.7	0.5	-0.6	0.9	0.0	-0.6	0.8	-1.7	-1.9
Alcohol usually taken with meals	0.7	1.1	4.6	-0.6	0.8	-1.6	-0.6	0.2	0.5	0.5	-2.1
Nervous feelings	0.8	1.5	3.1	-1.3	0.7	1.1	-1.1	1.5	-1.8	1.1	0.8
Frequency of tenseness / restlessness in last 2 weeks	2.3	3.5	6.6	-2.5	2.5	-1.0	-2.5	1.2	-2.6	-0.7	0.4
Hearing difficulty/problems with background noise	0.4	0.6	1.9	-0.6	-0.9	1.4	-0.4	0.0	-0.5	-0.1	1.3
Hair/balding pattern: Pattern 2	1.0	1.3	3.2	0.7	-0.6	0.8	0.5	-1.5	1.6	-0.8	-1.8
Had menopause	0.3	0.4	1.8	0.5	-0.5	1.3	0.4	-0.1	0.5	0.8	-0.1
Had other major operations	0.2	0.2	0.6	0.3	-0.5	0.3	0.4	-0.7	0.4	-0.1	-0.8
Forced vital capacity (FVC)	0.3	1.3	4.2	-1.3	0.1	-0.8	-1.1	-1.3	0.6	-0.2	-2.1
Heel bone mineral density (BMD) T-score, automated (right)	0.9	2.1	8.5	0.9	-1.5	-0.6	0.7	-2.9	2.0	0.2	-0.2
Ever unenthusiastic/disinterested for a whole week	0.2	0.2	1.2	0.3	1.1	0.3	0.3	0.2	-0.4	-0.2	0.2
Qualifications: None of the above	1.4	3.1	5.9	-1.9	1.5	-2.4	-1.5	1.4	-1.5	2.4	0.7
Financial difficulties in last 2 years	3.6	4.8	12.8	-3.6	1.0	-1.2	-3.6	-0.5	-0.8	0.3	-3.0
Mouth/teeth dental problems	0.4	0.7	3.6	-0.1	1.0	-0.0	-0.4	0.0	0.7	0.3	-1.9
Heart attack	0.5	0.6	2.4	0.0	-0.1	-1.6	0.0	-0.2	0.1	1.4	-0.7
Allergy	0.2	0.6	1.8	-0.4	1.0	-1.4	-0.5	0.4	-0.6	0.7	0.3
Pain all over the body in last month	0.3	0.3	1.2	0.1	-0.2	1.1	0.1	0.1	0.6	-0.4	-0.7
Diabetes (self-reported)	0.9	1.3	3.8	-1.2	1.1	-1.2	-1.3	1.0	-1.9	0.4	0.5
Hayfever/allergic rhinitis (self-reported)	0.2	0.3	0.8	0.3	-0.1	0.8	0.2	0.6	0.5	-0.1	-0.9
Medication: Ramipril	1.1	1.4	2.3	1.5	-1.3	1.4	1.4	-0.5	1.2	-0.2	-1.1
Medication: Simvastatin	0.4	0.6	1.3	-0.9	0.0	0.1	-1.0	0.2	-0.4	1.1	-1.1
Fluid intelligence score	2.1	4.4	16.2	1.3	-2.8	4.0	1.1	-1.9	1.9	0.3	-0.8
Illnesses of siblings	0.2	0.3	1.3	-0.7	-0.3	-0.1	-0.7	-0.1	-0.2	-1.1	-0.5
Neuroticism score	1.1	2.2	6.6	-2.0	1.4	-0.4	-1.9	1.2	-2.6	0.1	0.5
Weight	0.3	1.7	6.4	0.5	-0.6	-0.8	0.4	-1.7	1.4	0.7	-2.5
Impedance of arm (right)	1.4	6.6	15.1	-3.9	2.8	-2.5	-3.6	1.6	-2.5	-1.5	0.1
Arm fat percentage (right)	0.4	1.5	4.0	-1.0	-0.1	-1.3	-0.9	-1.6	0.4	-1.5	-2.0
Trunk fat-free mass	0.3	1.5	5.2	0.7	-0.5	0.3	0.6	-0.9	1.2	1.7	-2.3
Hip circumference	0.2	1.0	3.7	-0.2	0.0	-0.5	-0.3	-1.3	0.8	1.1	-1.9
Time employed in main current job	0.7	0.9	1.8	-0.1	-0.9	0.7	-0.3	-1.1	1.0	-1.2	-1.4
Alcohol intake versus 10 years previously	0.9	1.4	2.9	-1.2	1.7	-0.0	-1.3	1.3	-1.5	1.1	0.2
Father’s age at death	0.3	0.4	1.0	0.7	-0.6	0.9	0.6	0.0	0.6	-0.3	1.0
Worrier / anxious feelings	0.8	1.5	3.0	-1.7	1.6	0.2	-1.6	1.1	-1.7	0.3	-0.5
Frequency of tiredness / lethargy in last 2 weeks	2.4	3.9	7.7	-2.4	2.5	-0.6	-2.5	2.1	-2.8	-0.0	-0.2
Falls in the last year	1.3	1.7	4.1	2.0	-0.7	-1.4	2.0	0.3	0.5	0.9	1.3
Hair/balding pattern: Pattern 3	2.1	3.1	5.7	-1.6	1.7	-0.7	-1.4	2.4	-2.4	2.0	1.1
Number of live births	0.5	0.6	1.3	-0.2	0.9	-0.6	-0.4	1.1	-1.1	-1.1	0.1
Forced expiratory volume in 1-second (FEV1)	0.4	1.2	3.7	-0.4	-1.2	0.6	-0.2	-1.9	1.3	-0.9	-1.2
Pulse rate	2.0	3.4	6.3	-2.3	2.5	-0.5	-2.3	2.2	-2.1	-0.8	0.2
Happiness	0.2	0.3	0.5	-0.7	0.7	-0.7	-0.7	-0.3	-0.6	-0.2	0.2
Noisy workplace	2.6	3.2	5.9	-2.3	2.4	0.2	-2.1	2.0	-2.4	0.3	0.7
Qualifications: A levels/AS levels or equivalent	0.1	0.3	1.1	0.3	-0.2	1.1	0.4	-0.2	0.5	0.1	-0.8
Serious illness, injury or assault of a close relative in last 2 years	0.6	0.7	1.1	0.8	-1.1	0.4	0.9	-0.3	0.8	1.1	-0.8
Mouth/teeth dental problems: Dentures	1.4	2.3	11.6	-0.3	0.7	-0.7	0.1	1.4	-1.9	0.7	3.4
Asthma	0.4	0.7	1.9	-0.8	0.6	-0.8	-0.8	1.0	-1.4	0.4	0.8
Medication: Ibuprofen (e.g. Nurofen)	1.7	2.2	5.9	-0.9	1.6	-1.6	-0.6	1.7	-0.6	2.4	-1.3
Medication: Cholesterol lowering	0.6	0.9	4.0	-0.6	0.1	-1.4	-0.6	-0.4	0.1	0.6	-2.0
Depression (self-reported)	0.4	0.4	1.5	0.2	0.3	1.2	0.2	0.1	0.4	1.2	-0.4
Medication: Lansoprazole	0.2	0.3	0.7	0.0	0.7	-0.5	0.1	0.6	-0.1	-0.8	-0.5
Prospective memory result	1.2	1.5	4.6	-0.4	1.4	-0.7	-0.3	2.1	-1.3	1.7	0.6
Lung cancer (father)	0.1	0.1	0.3	-0.2	0.0	-0.3	-0.0	0.1	0.2	0.6	-0.2
Illnesses of mother	0.5	0.6	2.2	-0.4	0.3	-1.3	-0.4	0.0	0.1	-0.8	-1.5
Forced expiratory volume in 1-second (FEV1), Best measure	0.6	2.0	5.4	0.3	-1.8	0.9	0.4	-2.3	2.0	-0.5	-1.5
Pulse wave Arterial Stiffness index	0.9	1.1	4.1	-0.4	-0.2	0.2	-0.7	-1.2	0.9	-2.0	-1.2
Impedance of arm (left)	0.3	1.2	1.9	-1.3	1.3	-1.4	-1.0	0.5	-0.9	-1.4	0.8
Arm fat mass (right)	0.3	1.2	4.3	-0.0	-0.4	-1.0	-0.0	-1.7	1.0	-0.5	-2.1
Trunk predicted mass	0.2	1.4	4.9	0.8	-0.5	0.3	0.6	-0.9	1.2	1.7	-2.2
Standing height	0.2	2.2	4.3	-1.2	1.4	-2.0	-1.2	-0.2	-0.1	2.1	-2.1
Length of working week for main job	1.5	1.7	4.0	1.1	-0.3	1.8	1.1	1.0	-0.3	1.7	2.0
Exposure to tobacco smoke at home	0.9	1.0	2.4	-0.1	1.6	-0.4	-0.1	1.1	-1.3	-0.9	1.3
Breastfed as a baby	0.5	0.6	1.7	-0.3	1.0	-1.3	-0.4	0.7	-1.3	-0.2	0.1
Tense / ‘highly strung’	0.3	0.4	1.5	-0.3	0.8	-0.7	-0.3	0.6	-1.2	0.3	-0.3
Seen doctor (GP) for nerves, anxiety, tension or depression	1.6	2.4	5.7	-2.4	1.3	0.3	-2.4	1.5	-1.7	0.5	-0.8
Hair/balding pattern: Pattern 4	0.4	0.9	2.0	1.1	-1.4	-0.4	1.2	-0.2	1.2	-0.3	-1.1
Birth weight of first child	0.1	0.2	0.7	0.3	0.6	0.4	0.3	-0.5	0.3	-0.8	-0.4
Peak expiratory flow (PEF)	0.6	1.4	5.3	-0.1	-0.6	0.6	-0.3	-2.1	0.4	-2.3	-0.4
Pulse wave reflection index	1.2	1.5	4.2	0.7	-1.4	0.7	0.5	-1.8	1.2	-2.0	0.2
Ever highly irritable/argumentative for 2 days	0.3	0.3	1.1	1.1	0.1	0.0	1.1	-0.1	0.5	0.4	0.3
Loud music exposure frequency	0.4	0.5	1.1	0.7	-1.0	-0.3	0.7	-0.8	0.8	0.2	-0.4
Qualifications: O levels/GCSEs or equivalent	1.5	2.3	5.5	1.0	-1.3	1.4	1.0	-1.5	2.3	-0.8	-2.1
Mouth/teeth dental problems: Bleeding gums	1.0	1.2	2.9	1.2	-1.7	0.7	1.4	-1.0	0.8	-0.5	1.0
Blood clot in the leg (DVT)	0.5	0.6	2.5	0.5	-0.3	1.2	0.5	-0.1	-0.2	-0.5	1.6
Medication: Paracetamol	0.4	0.7	2.5	-0.3	0.1	1.3	-0.5	-0.5	0.2	-1.0	-1.6
Headache pain in last month	0.4	0.7	1.9	-0.7	1.2	-0.3	-0.8	0.8	-1.4	-0.6	0.3
Medication for cholesterol, blood pressure or diabetes	0.2	0.3	1.4	0.2	-0.6	0.9	0.1	-0.2	0.1	-0.2	1.2
Glaucoma (self-reported)	0.4	0.5	3.1	-0.1	-1.8	0.2	-0.2	-0.7	0.1	-0.3	0.4
Gout (self-reported)	0.8	1.1	2.9	-0.7	1.5	-0.2	-0.7	0.7	-1.0	-1.7	0.9
Hypothyroidism/myxoedema (self-reported)	1.8	3.5	6.2	2.2	-2.5	1.3	2.1	-0.8	2.2	2.0	-0.9
Medication: Amlodipine	0.2	0.3	0.6	0.8	0.6	-0.3	0.6	-0.3	0.0	-0.5	0.7
Medication: Ventolin 100micrograms inhaler	0.2	0.3	0.5	-0.5	0.3	-0.3	-0.5	0.7	-0.5	0.7	-0.1
Birth weight	3.0	6.4	15.2	3.9	-2.5	0.2	3.9	-2.4	2.8	-0.8	0.7
Chronic bronchitis/emphysema (mother)	1.5	1.8	4.7	-2.1	0.7	0.1	-2.2	0.8	-1.7	-0.8	0.9
High blood pressure (siblings)	1.5	2.2	4.0	1.8	-1.6	1.3	1.6	-2.0	1.7	-0.6	0.3
Forced vital capacity (FVC), Best measure	0.3	1.0	3.2	-0.6	-0.4	-0.3	-0.4	-1.6	1.1	-0.1	-1.8
Body fat percentage	0.4	1.6	4.6	-1.0	0.7	-2.1	-0.9	-1.1	0.3	-0.7	-2.1
Leg fat percentage (right)	0.6	2.2	4.2	-2.0	1.1	-2.1	-1.9	-0.5	-0.6	-1.1	-1.6
Arm fat-free mass (right)	0.4	2.2	5.0	1.7	-0.5	-0.2	1.5	-1.0	1.5	2.2	-1.9
Exposure to tobacco smoke outside home	0.5	0.6	2.0	0.8	-0.8	0.5	0.9	-0.0	0.8	1.4	-0.3
Comparative body size at age 10	12.6	34.7	64.8	7.5	-6.9	3.4	7.0	-6.4	8.1	-1.5	-2.2
Number of full brothers	0.2	0.2	1.3	-0.2	1.1	-0.0	-0.3	-0.4	-0.1	0.2	-0.3
Worry too long after embarrassment	0.3	0.5	1.3	0.1	-1.1	0.8	0.0	-1.1	0.2	-1.1	-0.1
Seen a psychiatrist for nerves, anxiety, tension or depression	1.4	1.9	4.3	-1.1	2.1	-0.7	-1.1	1.9	-1.9	0.2	0.6
Wheeze or whistling in the chest in last year	1.4	2.4	4.3	-1.6	1.7	-1.3	-1.7	2.1	-2.1	0.8	-0.3
Number of children fathered	3.4	3.8	8.2	-2.1	2.9	-2.1	-2.0	1.6	-2.3	-1.0	-0.5
Reason for reducing amount of alcohol drunk: Health precaution	1.3	1.5	4.5	1.8	-1.2	-0.1	2.1	-0.3	1.5	0.0	0.7
Age at first live birth	0.8	1.4	4.6	0.5	-1.0	0.8	0.5	-2.1	1.5	-1.1	-1.1
Pulse wave peak to peak time	0.8	1.0	4.5	0.5	0.1	-0.2	0.7	1.1	-0.6	2.1	1.0
Health satisfaction	0.3	0.4	2.0	-0.3	0.3	-0.3	-0.3	0.4	-1.0	0.1	1.4
Shortness of breath walking on level ground	2.6	3.1	5.7	-2.0	2.1	-1.2	-1.9	2.2	-2.4	0.6	0.9
Qualifications: College or University degree	0.9	2.8	4.2	1.8	-1.5	2.0	1.7	-2.0	1.9	-0.4	-1.4
Eye problems/disorders: None of the above	0.3	0.4	1.1	-0.1	1.0	0.5	-0.1	1.0	-0.2	-0.6	-0.2
Mouth/teeth dental problems: Loose teeth	1.6	1.9	5.2	-1.2	-0.3	0.4	-1.6	-1.1	0.2	-2.3	-2.2
Emphysema/chronic bronchitis	1.3	1.4	4.6	-0.6	1.1	-0.7	-0.6	2.1	-1.3	1.6	0.3
Medication for pain relief, constipation, heartburn	0.9	1.5	3.9	1.3	-1.0	0.7	1.3	-1.1	0.9	-0.9	2.0
Neck or shoulder pain in last month	1.0	1.5	5.9	1.0	-1.1	1.0	1.0	-0.2	0.5	-2.4	1.2
Medication: Blood pressure	0.2	0.4	1.4	0.0	0.9	-0.7	0.0	0.6	-0.3	-0.2	-1.2
Angina (self-reported)	0.7	0.9	3.8	0.0	0.6	-0.4	0.1	0.9	-0.9	1.9	1.0
Migraine (self-reported)	1.0	1.3	2.5	-1.4	0.7	0.1	-1.4	0.8	-1.5	-1.6	0.8
Medication: Ibuprofen	1.1	1.3	3.4	-0.7	1.4	-0.8	-0.4	1.4	-0.7	1.8	-1.0
Medication: Allopurinol	1.9	2.5	4.5	-1.5	1.9	-0.7	-1.6	1.4	-2.1	-1.4	1.6
Medication: Omeprazole	0.4	0.5	3.4	-0.5	0.1	0.0	-0.5	-0.1	0.5	0.3	-1.8
Medication: Seretide 50 evohaler	0.2	0.3	0.7	0.0	0.9	-0.2	0.0	0.8	-0.6	-0.5	-0.1
Mean time to correctly identify matches	6.4	12.2	22.2	4.4	-4.0	0.6	4.3	-3.1	4.7	2.6	-1.9
Heart disease (mother)	0.3	0.3	1.2	-0.2	0.0	1.1	-0.2	1.1	-0.3	0.0	-0.2
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.9	1.1	7.1	0.2	-0.3	-0.7	-0.0	-0.0	0.8	0.3	-2.7
Whole body fat mass	0.3	1.4	5.7	-0.3	0.2	-1.7	-0.3	-1.3	0.8	-0.0	-2.4
Leg fat mass (right)	0.4	1.4	4.5	-1.1	0.8	-1.8	-1.1	-0.8	0.0	-0.1	-2.1
Arm predicted mass (right)	0.4	2.2	5.6	1.5	-0.5	-0.0	1.3	-1.0	1.6	2.4	-2.1
Pulse rate, automated reading	4.2	13.6	27.5	-5.2	4.7	-1.9	-5.2	2.5	-4.3	-1.9	-0.5
Alcohol intake frequency.	1.7	3.9	7.6	-2.1	1.9	-2.8	-2.3	1.1	-1.6	0.8	-2.4
Comparative height size at age 10	0.4	2.2	5.9	0.3	-1.1	-0.9	0.3	-2.1	2.1	0.0	-2.4
Number of full sisters	0.8	1.0	1.8	-1.1	1.0	-0.2	-1.3	0.8	-0.8	0.9	-1.4
Suffer from ‘nerves’	0.8	1.3	2.5	-1.6	1.2	-1.3	-1.5	0.7	-1.4	0.0	-0.1
Overall health rating	0.8	1.7	3.5	-1.5	1.0	-1.9	-1.6	1.2	-1.6	0.3	-0.6
Chest pain or discomfort	1.8	2.6	5.0	-1.8	1.8	-0.7	-1.9	2.2	-2.1	0.4	-0.4
Had major operations	0.9	1.0	2.2	-0.6	1.5	-1.2	-0.5	1.4	-1.1	1.0	-0.2
Age at last live birth	1.7	2.5	6.1	0.8	-1.2	0.3	0.8	-2.5	1.9	-1.8	-2.0
Family relationship satisfaction	0.4	0.5	1.8	0.7	-1.3	-0.1	0.7	-0.8	0.7	-0.2	0.3
Leg pain on walking	1.6	2.0	4.9	-2.1	1.0	0.2	-2.2	1.1	-1.8	0.6	-0.7
Qualifications: NVQ or HND or HNC or equivalent	1.3	1.5	6.7	-1.4	-0.4	0.1	-1.6	-0.6	0.1	-2.6	-0.8
Commuting to job workplace: Car/motor vehicle	1.1	1.2	2.8	-1.5	0.6	-0.1	-1.7	0.4	-1.2	-1.7	-0.4
Illness, injury, bereavement, stress in last 2 years	0.9	1.1	3.1	1.2	-0.5	1.2	1.4	-0.2	0.6	-0.1	1.8
Medication: Aspirin	0.2	0.2	0.6	-0.3	0.1	-0.8	-0.4	0.4	-0.6	0.5	0.0
Supplements: Vitamin C	1.5	1.7	4.3	1.6	-1.3	1.1	1.3	-1.0	1.0	-2.1	0.4
Knee pain experienced in last month	0.1	0.2	0.5	-0.2	-0.6	0.5	-0.4	-0.2	-0.5	-0.7	0.4
Hypertension (Self-reported)	1.2	3.2	7.3	2.7	-1.7	1.6	2.7	-1.3	1.7	0.3	1.1
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	1.0	1.2	6.0	-0.1	-0.1	-0.8	0.0	-0.9	0.9	-1.0	-2.4
Illnesses of father: Heart disease	0.1	0.1	0.4	0.1	-0.2	0.5	0.1	0.7	0.2	0.2	-0.4
Illnesses of siblings: Diabetes	1.2	1.4	3.2	-1.1	1.7	-0.0	-1.0	1.8	-1.3	1.2	-0.2
Smoking status: Previous	0.7	1.1	4.7	0.5	-0.2	0.0	0.9	0.2	-0.2	1.7	2.2
Forced expiratory volume in 1-second (FEV1), predicted	0.2	0.5	1.1	-1.0	0.2	-0.8	-1.0	-0.2	-0.1	0.6	-0.8
Whole body fat-free mass	0.4	2.0	5.5	1.3	-0.7	0.2	1.2	-1.1	1.5	1.9	-2.4
Leg fat-free mass (right)	0.6	3.5	5.5	2.3	-1.4	0.4	2.2	-1.5	2.2	1.9	-2.1
Arm fat percentage (left)	0.3	1.3	3.3	0.2	-0.6	-0.9	0.3	-1.8	1.1	-1.3	-1.7
Average weekly red wine intake	1.2	1.8	4.1	0.7	-1.8	0.6	1.0	-1.9	2.0	-0.8	-1.1
Handedness (chirality/laterality): Left-handed	5.5	6.6	12.5	-3.4	3.3	-1.1	-3.5	1.9	-3.5	-0.3	0.7
Mood swings	3.4	6.2	13.7	-3.0	3.3	-0.7	-3.0	2.4	-3.7	-0.5	0.8
Loneliness, isolation	1.6	2.2	5.3	-0.8	0.8	0.5	-0.7	1.8	-2.3	1.6	2.1
Long-standing illness, disability or infirmity	1.0	1.6	3.7	-1.3	1.1	0.1	-1.4	1.9	-1.9	0.4	0.1
Ever had bowel cancer screening	1.0	1.1	3.9	0.0	-0.8	2.0	-0.1	-0.2	-0.6	-1.1	1.7
Diabetes diagnosed by doctor	0.7	1.2	3.0	-0.8	1.4	-1.2	-0.8	1.1	-1.7	0.8	0.2
Ever had stillbirth, spontaneous miscarriage or termination	2.1	2.2	5.4	0.1	-2.1	0.8	0.2	-2.3	1.7	-1.5	-1.5
Friendships satisfaction	0.2	0.2	0.8	0.1	0.3	-0.7	0.2	-0.5	-0.4	-0.0	0.9
Qualifications: nursing, teaching	0.3	0.4	1.6	0.8	0.8	-0.2	0.6	-0.0	-0.3	-1.3	-0.1
Commuting to job workplace: Walk	0.3	0.4	2.1	-0.1	0.3	-0.5	0.1	0.4	0.2	1.5	-0.5
Eye problems/disorders: Cataract	1.3	1.4	6.7	1.0	-0.4	-2.6	1.0	-1.1	0.8	0.7	-0.6
Mouth/teeth dental problems: Mouth ulcers	1.1	1.8	2.8	1.4	-1.6	0.7	1.4	-1.7	1.4	-1.0	-1.2
Medication for cholesterol	1.9	2.9	5.8	-2.4	2.3	-0.8	-2.4	1.2	-1.7	-1.1	-0.8
Medication: Laxatives (e.g. Dulcolax, Senokot)	1.0	1.2	2.5	1.0	-1.3	1.4	0.8	-0.0	1.1	1.6	-0.6
Back pain experienced in last month	0.6	0.8	1.3	-1.0	0.7	0.5	-1.1	0.9	-0.9	-0.7	-1.1
Mineral and other dietary supplements	4.1	5.5	11.5	-2.2	3.4	-2.0	-2.1	1.8	-3.3	-0.6	2.1
Breast cancer (self-reported)	1.0	1.2	3.4	-1.2	0.8	-1.1	-0.9	1.0	-0.8	1.8	-0.4
Asthma (self-reported)	0.5	1.0	2.1	-1.1	0.7	-1.2	-1.1	1.0	-1.5	0.5	0.1
Osteoporosis (self-reported)	4.2	5.2	10.6	-2.3	2.4	-3.3	-2.2	2.6	-2.8	0.6	0.5
Osteoarthritis (self-reported)	0.1	0.2	0.8	-0.4	0.4	-0.9	-0.2	0.1	-0.4	0.3	-0.3
Medication: Aspirin	0.0	0.1	0.2	-0.1	-0.3	-0.4	-0.2	0.1	-0.1	0.3	-0.1
Medication: Gliclazide	0.6	0.7	1.8	-0.7	1.1	-1.3	-0.6	0.7	-1.1	0.1	0.0
Illnesses of father: None of the above (group 1)	0.8	1.0	4.0	0.8	-0.9	0.1	0.8	-2.0	1.3	-0.1	-0.8
Smoking status: Current	1.2	1.9	5.5	-1.3	1.4	-2.4	-1.4	1.0	-1.4	-0.5	0.4
Forced expiratory volume in 1-second (FEV1), predicted percentage	1.2	2.6	5.4	1.1	-1.1	1.4	1.1	-2.3	2.2	-1.7	-1.4
Whole body water mass	0.4	2.2	5.4	1.4	-0.7	0.2	1.3	-1.2	1.6	1.9	-2.3
Leg predicted mass (right)	0.7	3.6	5.5	2.3	-1.4	0.4	2.2	-1.6	2.2	2.0	-2.2
Arm fat mass (left)	0.4	1.6	5.0	0.5	-0.7	-0.9	0.5	-2.0	1.4	-0.3	-2.2
Number of self-reported non-cancer illnesses	0.4	0.7	3.0	0.8	-0.0	0.1	0.8	1.0	-0.1	1.7	-0.2
Average weekly champagne plus white wine intake	0.4	0.5	1.0	0.5	-0.9	0.7	0.5	-0.7	1.0	-0.8	-0.3
Miserableness	0.4	0.7	1.7	-0.7	1.0	0.5	-0.6	0.9	-1.3	0.1	0.9
Guilty feelings	1.0	1.5	3.2	-1.8	1.1	0.5	-1.8	0.8	-1.7	0.6	-0.4
Wears glasses or contact lenses	0.7	0.9	3.4	0.1	1.3	-0.2	0.1	1.8	-0.9	0.8	0.6
Ever taken oral contraceptive pill	0.5	0.5	1.8	-1.3	0.5	-0.5	-0.9	0.2	-0.3	0.6	0.8
Hearing aid user	0.8	0.9	2.9	1.0	-1.0	0.0	1.2	-0.7	0.8	0.0	1.7
Mother’s age at death	1.1	1.4	3.4	1.8	-0.8	-0.2	1.8	-0.2	1.2	1.4	0.7
Financial situation satisfaction	4.2	5.2	8.9	-2.9	3.0	-1.3	-2.9	1.7	-3.0	0.0	1.5
Tinnitus: Yes, now most or all of the time	1.1	1.3	5.9	-1.1	0.2	0.3	-1.4	-0.5	-0.9	-2.4	0.1
Commuting to job workplace: Public transport	1.8	2.1	3.5	1.8	-1.9	1.0	1.8	-1.7	1.6	-0.5	-0.3
Eye problems/disorders: Glaucoma	1.0	1.1	4.0	0.4	-2.0	1.6	0.3	-0.9	0.6	-0.6	0.9
Medication: Blood pressure	2.3	4.3	8.4	2.6	-2.9	2.0	2.7	-1.4	2.0	0.5	1.4
Pain type(s) experienced in last month: Hip pain	1.9	2.4	9.0	0.3	-3.0	0.7	0.3	-2.0	1.4	-2.0	0.5
Supplements: Fish oil (including cod liver oil)	3.8	5.0	10.5	2.1	-3.2	1.2	2.0	-2.0	3.2	0.9	-2.1
High cholesterol (Self-reported)	2.0	3.5	6.8	1.5	-2.1	-1.4	1.4	-2.6	2.6	-0.3	-2.0
Medication: Bendroflumethiazide	1.5	2.3	4.9	2.1	-1.7	0.9	2.2	-0.9	1.8	-0.7	0.7
Medication: Paracetamol	0.5	0.8	2.9	-0.7	1.2	1.7	-0.8	0.4	-0.6	-0.5	-0.7
Medication: Lisinopril	0.2	0.3	1.0	0.4	-0.3	1.0	0.3	0.3	-0.3	0.6	0.7
Medication: Atorvastatin	0.9	1.1	3.1	1.1	-0.5	-1.8	1.2	-0.2	0.9	1.1	-1.0
Illnesses of father: High blood pressure	0.4	0.5	1.1	0.8	0.4	1.1	0.7	0.6	-0.2	-0.8	0.6
Alcohol drinker status: Never	0.2	0.3	1.4	-0.0	-0.5	-0.6	-0.1	-0.2	-0.2	-1.2	-0.1
Ever smoked	1.1	1.9	3.9	-1.0	1.1	-2.0	-0.6	1.0	-1.3	1.9	1.8
Basal metabolic rate	0.3	1.9	5.8	1.1	-0.7	-0.1	1.0	-1.4	1.6	1.5	-2.4
Leg fat percentage (left)	0.3	1.2	2.9	-1.0	0.2	-1.6	-1.0	-1.1	0.2	-0.6	-1.7
Arm fat-free mass (left)	0.4	1.9	6.7	0.6	-0.2	-0.7	0.4	-1.1	1.2	2.2	-2.6
Number of operations (self-reported)	1.5	2.3	5.4	-1.4	1.8	-0.0	-1.3	2.3	-1.6	1.8	-0.2
Average weekly beer plus cider intake	2.5	3.6	7.8	-1.4	2.6	-1.5	-1.5	2.5	-2.8	1.0	0.9
Irritability	1.2	2.1	8.2	-1.5	0.5	0.0	-1.8	-1.0	-0.9	-2.9	-1.0
Risk taking	0.4	0.6	1.8	0.1	0.7	0.3	-0.1	1.0	-1.1	-0.0	1.4
Ever had prostate specific antigen (PSA) test	3.2	3.7	7.6	2.0	-2.0	-1.2	2.0	-0.8	2.5	1.0	-2.8
Fractured/broken bones in last 5 years	6.4	8.3	18.1	-2.1	4.2	-2.4	-2.4	3.6	-4.3	0.1	1.4
Age started oral contraceptive pill	1.2	1.5	3.4	1.9	-0.8	1.6	1.6	-1.1	1.3	0.2	-0.2
Diastolic blood pressure, automated reading	0.2	0.6	1.2	0.8	-0.5	0.4	1.1	-1.1	1.1	0.1	0.1
Ever depressed for a whole week	0.7	0.8	2.5	-0.5	1.6	0.5	-0.5	1.3	-1.1	0.7	0.4
Unable to work because of sickness or disability	0.9	1.2	4.2	-1.3	-0.0	-0.2	-1.6	-0.4	-0.8	-2.1	-0.4
Commuting to job workplace: Cycle	1.6	2.0	4.2	1.5	-1.5	1.2	1.6	-1.5	2.0	0.7	-0.4
Myopia	0.7	1.0	2.7	1.5	-0.2	0.0	1.3	-0.3	0.9	1.6	0.5
Vascular/heart problems diagnosed by doctor	0.8	2.1	4.3	-2.1	1.2	-1.8	-2.1	0.7	-0.9	-0.8	-1.0
Cholesterol lowering medication	0.6	0.9	2.9	0.9	-1.7	-0.0	0.8	-1.0	1.0	0.7	0.4
Medication: Omeprazole (e.g. Zanprol)	0.8	1.0	4.2	0.2	-1.1	0.1	0.1	-1.0	1.3	0.3	-2.1
Pain experienced in last month	0.4	0.6	2.8	-0.2	0.7	-1.3	-0.1	0.2	-0.2	1.7	-0.2
Supplements: Calcium	0.2	0.2	0.8	-0.2	-0.2	0.2	-0.2	0.6	-0.9	-0.6	0.4
Basal cell carcinoma (self-reported)	0.6	0.7	2.1	0.0	-1.4	0.4	-0.0	-1.2	1.4	0.1	-0.2
Heart attack/myocardial infarction (self-reported)	0.5	0.6	2.7	-0.1	-0.0	-1.6	-0.1	-0.3	-0.0	1.4	-0.6
Deep venous thrombosis (DVT) (self-reported)	0.5	0.6	2.7	0.5	-0.1	1.3	0.6	0.1	-0.3	-0.4	1.6
Heart disease (siblings)	1.5	1.9	5.4	-0.9	1.2	-0.6	-0.7	2.1	-1.3	2.3	-0.4
Alcohol drinker status: Previous	1.3	1.4	2.2	-1.4	1.4	-1.3	-1.5	0.7	-0.9	-0.9	-1.2
Pack years of smoking	2.3	3.4	8.0	-1.8	2.0	-2.8	-2.0	1.4	-2.5	-0.5	-0.2
Impedance of whole body	0.9	4.5	9.1	-3.0	2.4	-2.3	-2.8	1.5	-2.2	-0.8	1.0
Leg fat mass (left)	0.3	1.2	5.4	-0.5	0.3	-1.5	-0.6	-1.1	0.5	0.2	-2.3
Arm predicted mass (left)	0.3	1.5	5.1	0.6	-0.1	-0.2	0.5	-0.9	1.1	2.1	-2.3