TWAS
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Traits
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Traits
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Past tobacco smoking
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chr12:111,193,499-113,137,832
Best TWAS P=3.24e-08 · Best GWAS P=2.14e-11 conditioned to 1.65e-05
111.5M
112M
112.5M
113M
0
2
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physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
1
CommonMind
Brain Pre-frontal Cortex
ATXN2
0.02
0.03
enet
8
0.02
4.8e-04
3.9
-5.5
3.2e-08
0.57
0.24
0.67
TRUE
3
GTEx
Stomach
TMEM116
0.13
0.03
lasso
7
0.03
1.6e-02
4.3
5.2
2.0e-07
-0.48
0.07
0.16
FALSE
2
GTEx
Skin Sun Exposed Lower leg
ALDH2
0.10
0.09
enet
13
0.13
6.7e-11
3.8
-5.1
2.7e-07
0.64
0.96
0.04
FALSE