Best TWAS P=3.24e-08 · Best GWAS P=2.14e-11 conditioned to 1.65e-05
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | ATXN2 | 0.02 | 0.03 | enet | 8 | 0.02 | 4.8e-04 | 3.9 | -5.5 | 3.2e-08 | 0.57 | 0.24 | 0.67 | TRUE |
| 2 | GTEx | Skin Sun Exposed Lower leg | ALDH2 | 0.10 | 0.09 | enet | 13 | 0.13 | 6.7e-11 | 3.8 | -5.1 | 2.7e-07 | 0.64 | 0.96 | 0.04 | FALSE |
| 3 | GTEx | Stomach | TMEM116 | 0.13 | 0.03 | lasso | 7 | 0.03 | 1.6e-02 | 4.3 | 5.2 | 2.0e-07 | -0.48 | 0.07 | 0.16 | FALSE |