[Hub]/) : Traits : Past tobacco smoking : ← →

chr15:66,850,204-68,789,191

Best TWAS P=8.42e-09 · Best GWAS P=2.65e-08 conditioned to 0.07

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex IQCH 0.13 0.11 bslmm 597 0.10 5.9e-12 4.7 -5.3 1.4e-07 0.52 0.28 0.71 FALSE
2 GTEx Brain Cerebellum MAP2K5 0.27 0.12 lasso 5 0.14 7.9e-05 4.6 -5.3 9.2e-08 0.46 0.20 0.59 FALSE
3 GTEx Brain Hippocampus IQCH-AS1 0.20 0.08 enet 11 0.05 2.2e-02 -5.6 5.7 1.2e-08 -0.93 0.04 0.79 FALSE
4 GTEx Heart Atrial Appendage MAP2K5 0.16 0.08 lasso 5 0.16 1.3e-07 4.6 -5.3 9.2e-08 0.75 0.08 0.92 FALSE
5 GTEx Muscle Skeletal MAP2K5 0.08 0.03 lasso 6 0.05 1.9e-05 -5.3 -5.8 8.4e-09 0.76 0.02 0.98 TRUE
6 GTEx Skin Sun Exposed Lower leg MAP2K5 0.13 0.06 lasso 4 0.09 4.4e-08 -5.2 -5.7 1.2e-08 0.88 0.01 0.98 FALSE
7 NTR Blood MAP2K5 0.02 0.00 enet 13 0.01 5.7e-04 4.7 -5.3 1.3e-07 0.61 0.14 0.83 FALSE
8 The Cancer Genome Atlas Breast Invasive Carcinoma IQCH 0.06 0.05 blup 112 0.06 5.2e-12 4.7 -5.5 3.6e-08 0.60 0.03 0.96 FALSE
9 The Cancer Genome Atlas Colon Adenocarcinoma IQCH 0.08 0.02 blup 111 0.05 4.2e-04 4.2 -5.2 2.0e-07 0.63 0.06 0.81 FALSE
10 The Cancer Genome Atlas Glioblastoma Multiforme IQCH 0.19 0.14 enet 21 0.12 2.4e-04 4.2 -5.3 1.4e-07 0.67 0.08 0.78 FALSE
11 The Cancer Genome Atlas Brain Lower Grade Glioma IQCH 0.05 0.04 blup 111 0.04 7.7e-06 4.2 -5.3 1.1e-07 0.70 0.08 0.87 FALSE
12 The Cancer Genome Atlas Ovarian Serous Cystadenocarcinoma IQCH 0.11 0.10 blup 112 0.10 2.3e-07 4.8 -5.6 2.6e-08 0.73 0.02 0.97 FALSE
13 The Cancer Genome Atlas Thyroid Carcinoma IQCH 0.15 0.17 enet 19 0.17 1.3e-16 4.2 -5.5 3.6e-08 0.75 0.20 0.71 FALSE