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chr15:66,850,204-68,789,191

Best TWAS P=8.42e-09 · Best GWAS P=2.65e-08 conditioned to 0.07

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
5	GTEx	Muscle Skeletal	MAP2K5	0.08	0.03	lasso	6	0.05	1.9e-05	-5.3	-5.8	8.4e-09	0.76	0.02	0.98	TRUE
3	GTEx	Brain Hippocampus	IQCH-AS1	0.20	0.08	enet	11	0.05	2.2e-02	-5.6	5.7	1.2e-08	-0.93	0.04	0.79	FALSE
6	GTEx	Skin Sun Exposed Lower leg	MAP2K5	0.13	0.06	lasso	4	0.09	4.4e-08	-5.2	-5.7	1.2e-08	0.88	0.01	0.98	FALSE
12	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	IQCH	0.11	0.10	blup	112	0.10	2.3e-07	4.8	-5.6	2.6e-08	0.73	0.02	0.97	FALSE
8	The Cancer Genome Atlas	Breast Invasive Carcinoma	IQCH	0.06	0.05	blup	112	0.06	5.2e-12	4.7	-5.5	3.6e-08	0.60	0.03	0.96	FALSE
13	The Cancer Genome Atlas	Thyroid Carcinoma	IQCH	0.15	0.17	enet	19	0.17	1.3e-16	4.2	-5.5	3.6e-08	0.75	0.20	0.71	FALSE
2	GTEx	Brain Cerebellum	MAP2K5	0.27	0.12	lasso	5	0.14	7.9e-05	4.6	-5.3	9.2e-08	0.46	0.20	0.59	FALSE
4	GTEx	Heart Atrial Appendage	MAP2K5	0.16	0.08	lasso	5	0.16	1.3e-07	4.6	-5.3	9.2e-08	0.75	0.08	0.92	FALSE
11	The Cancer Genome Atlas	Brain Lower Grade Glioma	IQCH	0.05	0.04	blup	111	0.04	7.7e-06	4.2	-5.3	1.1e-07	0.70	0.08	0.87	FALSE
7	NTR	Blood	MAP2K5	0.02	0.00	enet	13	0.01	5.7e-04	4.7	-5.3	1.3e-07	0.61	0.14	0.83	FALSE
1	CommonMind	Brain Pre-frontal Cortex	IQCH	0.13	0.11	bslmm	597	0.10	5.9e-12	4.7	-5.3	1.4e-07	0.52	0.28	0.71	FALSE
10	The Cancer Genome Atlas	Glioblastoma Multiforme	IQCH	0.19	0.14	enet	21	0.12	2.4e-04	4.2	-5.3	1.4e-07	0.67	0.08	0.78	FALSE
9	The Cancer Genome Atlas	Colon Adenocarcinoma	IQCH	0.08	0.02	blup	111	0.05	4.2e-04	4.2	-5.2	2.0e-07	0.63	0.06	0.81	FALSE