TWAS hub - GSDMB

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Brain Cerebellum	0.2410	0.0950	8.6e-03	0.090	NA	0.042	NA	0.082	1.3e-03	NA	2.2e-02	NA	2.0e-03
2	GTEx	Brain Putamen basal ganglia	0.2630	0.0910	1.6e-03	0.091	NA	0.200	NA	0.203	3.6e-03	NA	1.7e-05	NA	1.5e-05
3	GTEx	Cells Transformed fibroblasts	0.1110	0.0390	1.1e-05	0.018	NA	0.056	NA	0.041	1.5e-02	NA	4.9e-05	NA	5.0e-04
4	GTEx	Colon Transverse	0.1440	0.0500	7.8e-06	0.108	NA	0.122	NA	0.008	7.9e-06	NA	2.0e-06	NA	1.2e-01
5	GTEx	Esophagus Mucosa	0.0630	0.0350	5.3e-03	0.043	NA	0.024	NA	0.029	7.4e-04	NA	9.3e-03	NA	4.8e-03
6	GTEx	Lung	0.0742	0.0329	3.2e-04	0.068	NA	0.028	NA	0.047	6.9e-06	NA	3.1e-03	NA	1.6e-04
7	GTEx	Spleen	0.4960	0.0900	2.1e-09	0.451	NA	0.433	NA	0.008	4.9e-13	NA	1.9e-12	NA	1.9e-01
8	GTEx	Uterus	0.3220	0.1250	5.6e-03	-0.012	NA	-0.012	NA	-0.015	6.8e-01	NA	6.7e-01	NA	9.2e-01
9	GTEx	Whole Blood	0.1470	0.0470	2.0e-07	0.099	NA	0.082	NA	0.095	2.1e-09	NA	4.8e-08	NA	4.5e-09
10	METSIM	Adipose	0.0790	0.0333	5.1e-05	0.040	0.034	0.049	0.045	0.040	9.9e-07	6.5e-06	6.2e-08	2.3e-07	1.1e-06
11	NTR	Blood	0.0876	0.0214	0.0e+00	0.100	0.077	0.118	0.080	0.086	1.5e-30	1.1e-23	3.8e-36	1.5e-24	1.9e-26
12	YFS	Blood	0.3645	0.0449	0.0e+00	0.414	0.462	0.487	0.482	0.489	1.6e-148	5.0e-172	5.2e-185	1.3e-182	4.0e-186
13	TCGA	Colon Adenocarcinoma	0.1020	0.0440	2.1e-09	0.154	0.143	0.124	NA	0.136	3.1e-09	1.2e-08	1.2e-07	NA	2.9e-08
14	TCGA	Brain Lower Grade Glioma	0.0602	0.0315	5.5e-06	0.051	0.029	0.050	NA	0.020	1.7e-06	2.8e-04	2.2e-06	NA	2.4e-03
15	TCGA	Lung Adenocarcinoma	0.0452	0.0243	7.7e-07	0.066	0.050	0.032	NA	0.030	3.3e-08	1.4e-06	1.2e-04	NA	1.9e-04
16	TCGA	Lung Squamous Cell Carcinoma	0.0200	0.0146	5.2e-03	0.007	0.012	0.003	NA	0.007	4.7e-02	1.5e-02	1.2e-01	NA	4.9e-02
17	TCGA	Pancreatic Adenocarcinoma	0.1450	0.0640	4.9e-06	0.162	0.135	0.111	NA	0.137	2.5e-07	2.7e-06	2.2e-05	NA	2.4e-06
18	TCGA	Rectum Adenocarcinoma	0.1450	0.0760	1.7e-04	0.092	0.174	0.149	NA	0.135	3.7e-03	7.0e-05	2.4e-04	NA	4.6e-04
19	TCGA	Stomach Adenocarcinoma	0.0590	0.0290	1.1e-07	0.081	0.073	0.084	NA	0.038	1.7e-06	5.9e-06	1.1e-06	NA	9.7e-04
20	TCGA	Thyroid Carcinoma	0.0800	0.0360	1.8e-08	0.078	0.088	0.070	NA	0.071	5.2e-08	6.6e-09	2.2e-07	NA	2.1e-07

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	9	10	11	12	13	14	15	16	17	18	19	20
Blood White Count	89.1	660.3	1075.8	3.0	7.5	26.4	30.8	32.8	26.5	30.0	26.9	7.7	23.8	23.9	28.4	25.5	29.0	29.6	28.1	32.0	30.8	31.0
Respiratory disease	88.5	196.9	269.0	3.8	6.1	12.0	16.1	13.9	16.4	15.8	15.5	8.7	14.6	14.9	15.8	15.2	15.9	16.2	15.6	16.2	16.4	15.8
Asthma (self-reported)	82.3	163.8	228.0	3.5	5.1	10.7	14.9	12.7	14.9	14.3	14.4	6.8	13.2	13.3	14.4	14.0	14.5	15.0	14.4	14.8	15.1	14.7
Asthma	79.8	157.4	216.1	3.6	5.2	10.5	14.5	12.5	14.6	14.0	14.1	6.8	13.0	13.1	14.1	13.8	14.2	14.7	14.0	14.5	14.7	14.4
Allergy	41.2	94.8	130.0	-5.3	-5.8	-9.1	-11.1	-10.4	-11.3	-11.3	-10.7	-5.9	-9.8	-9.8	-10.2	-10.9	-11.3	-10.7	-9.8	-10.8	-10.9	-11.4
Medication: Ventolin 100micrograms inhaler	32.8	42.2	57.5	2.2	3.0	5.0	7.3	6.5	7.3	7.0	7.5	4.5	7.0	7.1	7.5	7.3	7.2	7.6	7.2	7.3	7.6	7.1
Irritable Bowel Disease (IBD)	27.3	65.1	104.0	0.1	-1.8	-5.7	-8.8	-8.3	-7.3	-8.3	-10.0	-4.2	-9.7	-9.6	-9.9	-8.2	-8.4	-9.6	-10.2	-9.9	-9.3	-8.6
Wheeze or whistling in the chest in last year	22.7	40.5	57.6	4.0	4.3	7.2	6.9	6.2	7.6	6.8	6.8	3.4	6.7	6.4	6.6	7.2	7.4	6.8	6.2	7.0	7.0	7.4
Primary Biliary Cirrhosis	21.1	30.0	44.1	-2.7	-2.9	-5.3	-5.6	-4.8	-6.3	-5.7	-6.5	-4.0	-6.2	-6.2	-5.5	-6.4	-6.2	-6.2	-5.7	-5.8	-5.9	-6.6
Ulcerative Colitis (UC)	19.6	36.8	59.9	0.5	-0.4	-3.9	-7.1	-6.4	-5.3	-6.3	-7.6	-2.7	-7.0	-6.8	-7.2	-6.1	-6.3	-7.3	-7.7	-7.4	-7.2	-7.0
Crohns Disease (2017)	19.5	42.8	68.0	-0.3	-2.4	-5.0	-6.8	-6.4	-6.1	-6.8	-7.9	-3.8	-7.9	-8.0	-8.1	-6.8	-6.9	-7.7	-8.2	-8.1	-7.4	-6.5
HDL Cholesterol	18.9	31.6	44.6	-3.2	-3.8	-6.2	-6.4	-5.6	-6.7	-6.4	-6.1	-4.6	-6.0	-6.0	-5.7	-6.0	-6.3	-5.9	-5.5	-5.9	-6.0	-6.0
Hayfever, allergic rhinitis or eczema	18.9	41.0	58.8	4.9	4.7	6.7	6.9	7.3	7.7	7.5	6.9	3.9	6.1	6.1	6.2	7.2	7.5	6.6	5.7	6.8	6.8	7.7
Allergy or Eczema	17.0	44.6	63.4	4.2	4.7	6.7	7.2	7.3	7.9	8.0	7.1	4.4	6.6	6.5	6.7	7.5	7.8	7.1	6.3	7.3	7.3	7.9
Ulcerative Colitis	16.7	24.2	38.9	0.0	-0.9	-3.6	-5.7	-5.1	-4.9	-5.4	-6.2	-2.5	-5.4	-5.5	-5.6	-5.0	-5.2	-5.9	-5.9	-5.9	-5.6	-5.8
Hayfever/allergic rhinitis (self-reported)	16.3	21.5	31.4	4.0	3.8	4.9	4.7	4.1	5.3	4.9	5.4	4.0	5.1	4.7	4.4	5.6	5.3	4.8	4.2	4.6	4.7	5.4
Supplements: Vitamin C	11.7	13.9	18.9	1.7	2.7	3.0	4.3	3.2	3.9	4.3	4.2	2.6	3.9	4.1	4.3	4.3	4.2	4.3	4.2	4.2	4.3	3.6
Lupus	11.6	17.6	30.8	-5.5	-5.1	-5.0	-4.3	-3.4	-5.0	-4.3	-4.1	-3.4	-3.4	-3.8	-3.5	-5.1	-5.0	-3.8	-2.8	-3.8	-4.0	-4.9
Taking other prescription medications	11.1	17.1	24.2	2.2	2.5	4.8	4.5	4.9	4.6	4.8	4.5	1.1	3.9	3.7	4.3	4.6	4.8	4.4	4.1	4.8	4.7	4.9
Crohns Disease (2012)	10.7	17.3	28.0	0.2	-2.0	-3.8	-3.9	-4.5	-3.9	-4.2	-5.3	-1.7	-5.0	-5.2	-5.2	-4.3	-4.3	-4.7	-5.2	-5.3	-4.4	-3.9
Myopia	10.4	15.1	20.8	3.5	4.4	3.5	3.5	3.6	4.4	4.3	4.3	3.4	4.2	4.3	3.9	4.6	4.5	4.0	3.6	4.0	4.0	3.5
Number of self-reported non-cancer illnesses	9.7	16.8	28.8	2.9	2.9	4.7	4.6	3.2	4.7	4.5	4.5	2.9	3.9	4.0	4.0	4.8	4.8	4.4	3.9	4.5	4.5	5.4
Rheumatoid Arthritis	9.2	12.7	19.6	-0.4	-0.3	-2.1	-4.4	-1.7	-4.0	-3.4	-4.3	-3.8	-4.3	-4.3	-3.9	-3.9	-3.6	-4.4	-4.3	-3.5	-3.9	-4.3
Mouth/teeth dental problems: Mouth ulcers	8.3	13.2	27.7	1.8	-0.2	-2.4	-3.9	-3.2	-2.9	-3.5	-4.2	-1.6	-4.2	-4.3	-4.8	-3.5	-3.7	-4.5	-5.3	-4.8	-4.5	-3.4
Medication: Seretide 50 evohaler	7.5	8.6	15.4	1.5	1.3	3.1	3.4	1.9	3.8	3.2	3.2	1.8	2.7	2.8	2.9	3.4	3.4	3.3	3.1	3.3	3.5	3.9
Forced expiratory volume in 1-second (FEV1), predicted percentage	7.5	15.9	27.8	-3.5	-2.7	-5.3	-4.4	-3.5	-5.0	-4.4	-4.2	-2.7	-3.8	-3.8	-4.0	-4.5	-4.5	-3.9	-3.3	-4.0	-4.0	-5.1
Chest pain or discomfort	7.1	10.2	19.6	1.9	1.8	3.0	3.9	2.6	3.8	3.4	3.4	1.5	2.8	2.9	3.2	3.7	3.8	3.7	3.3	3.8	3.7	4.4
Emphysema/chronic bronchitis	7.0	7.9	14.6	-0.1	0.4	2.8	3.8	2.2	2.7	3.2	3.0	1.6	2.6	2.8	3.3	2.9	3.0	3.4	3.5	3.4	3.5	3.2
Mouth/teeth dental problems: Dentures	6.8	11.4	16.5	2.1	2.4	3.8	3.5	2.7	3.7	3.5	3.7	3.6	4.1	3.9	3.4	3.6	3.9	3.5	3.3	3.6	3.4	3.6
Gout (self-reported)	6.3	8.7	12.7	-2.2	-2.4	-3.0	-3.1	-2.0	-3.1	-3.2	-3.4	-2.9	-3.1	-3.2	-2.9	-3.6	-3.3	-3.4	-3.1	-2.9	-3.2	-3.0
Wears glasses or contact lenses	6.3	7.3	12.1	0.4	-0.5	-1.9	-3.1	-2.3	-3.1	-2.7	-3.3	-1.9	-2.8	-3.0	-3.1	-2.8	-3.0	-3.3	-3.5	-3.3	-3.3	-2.9
Bipolar Disorder (2018)	5.6	8.9	15.6	1.5	1.6	2.0	3.9	3.0	3.4	3.9	3.1	2.6	2.9	2.9	3.1	3.1	3.5	3.3	2.8	3.2	3.4	3.5
Average weekly red wine intake	5.6	8.3	15.6	-1.9	-1.4	-2.4	-3.6	-1.9	-2.8	-3.1	-3.5	-2.7	-3.1	-3.0	-2.7	-3.4	-3.1	-3.3	-2.9	-2.8	-3.1	-4.0
Basal cell carcinoma (self-reported)	4.9	5.8	9.9	0.9	0.9	1.9	3.1	2.9	2.4	2.6	2.7	1.9	2.5	2.4	2.3	2.6	2.7	2.7	2.5	2.7	2.7	3.1
Ever depressed for a whole week	4.7	5.8	12.4	2.6	1.9	3.5	2.8	2.0	3.2	2.7	2.6	1.1	1.6	1.7	1.9	2.9	2.8	2.4	1.7	2.2	2.5	3.4
Heart disease (mother)	4.6	5.6	7.5	1.8	2.4	2.5	2.5	2.5	2.7	2.7	2.2	2.2	2.6	2.5	2.5	2.6	2.7	2.4	2.0	2.4	2.5	2.3
Lung FEV1/FVC ratio	4.4	22.1	46.1	-1.5	-3.2	-6.8	-4.2	-4.5	-4.4	-5.9	-4.8	-2.9	-5.4	-5.2	-5.6	-4.8	-5.1	-5.1	-4.9	-5.3	-5.3	-4.0
Schizophrenia vs Biploar Disorder	4.2	5.6	12.8	-2.4	-1.1	-2.8	-2.6	-1.4	-2.5	-3.0	-2.4	-1.9	-1.9	-2.2	-2.0	-2.8	-2.7	-2.7	-1.8	-2.1	-2.7	-3.6
Number of treatments/medications taken	4.2	7.6	13.5	1.6	2.1	3.7	3.1	2.6	2.8	3.0	2.9	1.8	2.8	2.6	2.8	3.0	3.2	2.9	2.6	3.2	3.1	3.2
Bipolar Disorder or Schizophrenia	4.1	10.0	16.4	0.9	1.5	1.9	4.0	3.3	3.6	4.0	3.5	2.8	3.2	3.2	3.4	3.3	3.5	3.6	3.4	3.6	3.6	3.4
Alcohol intake frequency.	3.8	8.8	15.9	1.9	1.9	1.8	4.0	2.2	3.8	3.3	3.2	3.3	2.9	3.0	2.8	3.3	3.4	3.3	2.7	3.1	3.2	3.6
Miserableness	3.6	6.3	13.6	2.6	1.7	3.7	2.6	2.4	2.7	3.1	2.7	-0.1	1.8	1.5	2.1	3.1	2.9	2.6	1.9	2.5	2.8	3.7
Family relationship satisfaction	3.4	4.1	10.5	1.5	0.3	1.4	2.5	2.1	2.5	2.5	2.4	0.7	1.7	1.7	1.8	2.4	2.4	2.4	1.8	2.0	2.3	3.2
Qualifications: None of the above	3.3	7.0	11.3	1.6	1.9	3.4	2.8	2.0	2.5	2.6	3.0	2.8	3.1	3.0	2.8	3.0	3.0	2.7	2.6	2.8	2.7	2.8
Father’s age at death	3.3	4.5	6.8	-1.4	-1.7	-2.4	-2.4	-1.3	-2.0	-2.4	-2.5	-2.6	-2.6	-2.4	-2.1	-2.4	-2.1	-2.2	-2.0	-2.0	-2.1	-2.0
Eye problems/disorders: None of the above	3.3	3.8	6.2	0.9	2.0	1.6	2.1	2.5	2.1	2.3	2.0	2.1	2.2	2.2	2.5	1.9	2.0	1.8	1.9	2.2	1.9	0.9
Long-standing illness, disability or infirmity	3.2	4.9	9.4	0.9	2.1	3.1	2.4	1.7	2.7	2.5	2.0	2.0	2.2	2.3	2.4	2.3	2.5	2.1	2.2	2.6	2.3	2.1
Ever had bowel cancer screening	3.2	3.8	7.1	-0.1	-0.6	-1.1	-2.1	-1.7	-1.9	-1.9	-2.5	-0.8	-2.2	-2.3	-2.5	-2.1	-2.1	-2.5	-2.7	-2.3	-2.5	-1.6
Vitamin and mineral supplements	3.0	4.1	8.0	-0.4	-1.3	-1.4	-2.3	-1.7	-1.9	-2.8	-2.0	-1.9	-2.0	-2.1	-2.4	-2.1	-2.2	-2.4	-2.3	-2.4	-2.4	-1.8
Exposure to tobacco smoke outside home	3.0	4.0	9.7	1.8	1.1	2.1	1.8	2.0	2.0	3.1	2.1	0.6	1.8	1.9	1.9	2.2	2.5	2.2	1.7	2.1	2.4	2.5
Impedance of arm (right)	2.9	13.5	27.4	2.1	3.9	5.0	2.8	5.2	3.5	4.1	3.5	1.9	3.8	3.7	3.9	3.8	4.4	3.6	3.3	4.4	3.9	3.1
Medication: Allopurinol	2.9	3.9	6.5	-2.4	-2.5	-2.3	-1.7	-1.1	-2.1	-1.7	-2.2	-2.1	-1.9	-2.1	-1.7	-2.5	-2.2	-2.0	-1.8	-1.6	-1.9	-1.7
Impedance of arm (left)	2.8	12.8	23.2	1.9	3.8	4.6	2.9	4.8	3.5	4.1	3.5	2.3	3.8	3.7	3.9	3.7	4.2	3.5	3.3	4.2	3.8	2.9
Reason for reducing amount of alcohol drunk: Health precaution	2.8	3.3	6.4	-2.1	-1.1	-2.4	-1.6	-0.9	-2.5	-1.6	-1.8	-2.3	-2.2	-2.0	-1.3	-2.1	-2.0	-1.7	-1.3	-1.3	-1.5	-2.4
Blood Eosinophil Count	2.7	21.1	108.2	10.4	9.2	8.5	1.2	5.4	5.8	3.6	1.5	1.0	1.3	1.3	1.1	4.1	4.9	0.9	-1.3	2.4	2.0	4.4
Bipolar Disorder (2011)	2.6	2.5	7.2	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	1.5	0.0	1.9	2.5	1.8	2.0	2.4	2.7	2.7	2.5	2.2
Medication: Laxatives (e.g. Dulcolax, Senokot)	2.6	3.0	4.6	1.5	2.0	2.0	1.4	1.9	1.9	2.1	1.8	1.1	1.6	1.6	1.8	2.0	2.1	1.6	1.5	2.0	1.8	1.6
Chronic bronchitis/emphysema (father)	2.5	2.9	6.1	0.9	1.4	1.6	2.5	2.4	1.4	1.9	1.8	1.2	1.6	1.6	1.9	1.8	1.9	1.7	1.6	1.9	1.9	1.5
Number of incorrect matches in round	2.5	4.2	7.5	-0.5	0.1	1.9	2.7	0.9	1.5	2.3	2.4	2.5	2.6	2.4	2.3	2.0	1.9	2.5	2.7	2.2	2.3	1.7
Ever smoked	2.5	4.4	12.1	1.8	0.8	2.5	2.6	1.6	2.9	2.0	2.3	0.4	1.5	1.5	1.9	2.5	2.4	2.2	1.9	2.1	2.2	3.5
Heart attack/myocardial infarction (self-reported)	2.5	3.3	8.8	2.4	2.9	3.0	1.5	1.6	1.9	1.5	1.6	1.4	1.5	1.6	1.3	2.1	2.2	1.5	1.2	1.7	1.6	1.5
Lung FVC	2.4	12.5	21.9	-3.5	-3.4	-3.6	-3.7	-3.6	-4.7	-3.0	-3.6	-3.4	-3.5	-3.7	-3.5	-3.9	-4.1	-3.3	-2.8	-3.7	-3.3	-4.2
Number of live births	2.4	3.4	7.3	1.4	1.4	2.1	2.7	2.2	2.4	1.7	1.9	1.1	1.6	1.8	1.7	2.2	2.1	1.9	1.7	1.9	1.9	1.9
Qualifications: College or University degree	2.4	7.6	13.2	-3.5	-2.9	-3.5	-3.1	-1.5	-3.2	-2.5	-3.4	-1.9	-2.6	-2.6	-2.6	-3.6	-3.0	-2.4	-2.4	-2.5	-2.5	-3.0
Friendships satisfaction	2.4	3.0	7.0	1.0	0.3	1.0	2.2	1.6	2.2	2.2	2.0	0.5	1.4	1.4	1.6	1.9	2.1	2.1	1.6	1.8	2.2	2.6
Diabetes (father)	2.3	2.9	5.6	0.7	0.2	1.2	2.2	0.5	1.8	1.3	1.9	1.8	1.9	2.2	1.8	2.0	1.7	2.2	1.9	1.6	1.8	2.4
Serious illness, injury or assault to yourself	2.3	2.7	5.2	0.2	0.9	0.9	2.3	1.3	1.7	2.1	1.9	1.4	1.2	1.4	1.8	1.7	1.9	2.0	1.9	2.1	2.1	1.9
Heart attack	2.3	2.9	9.1	2.4	3.0	2.9	1.2	1.4	1.8	1.3	1.4	1.5	1.4	1.5	1.1	2.0	2.0	1.3	1.0	1.5	1.4	1.3
Medication: Lisinopril	2.3	3.0	5.9	-0.9	-0.7	-1.0	-2.0	-1.8	-1.9	-1.8	-1.9	-1.1	-1.6	-1.8	-1.7	-2.0	-2.1	-2.1	-1.7	-1.9	-2.1	-2.4
Type 2 Diabetes (T2D) (2018)	2.2	4.1	9.6	1.0	0.4	2.2	2.2	1.5	2.7	2.2	2.3	1.1	2.0	2.1	2.1	2.2	2.2	2.3	2.0	2.2	2.2	3.1
Forced expiratory volume in 1-second (FEV1), Best measure	2.1	6.6	14.3	-1.5	-2.7	-3.1	-2.1	-2.1	-2.8	-2.8	-2.3	-3.8	-3.3	-3.4	-3.0	-2.4	-2.6	-2.3	-2.2	-2.5	-2.3	-1.4
Birth weight of first child	2.1	3.8	8.7	-0.1	-1.0	2.4	2.7	1.4	1.9	2.0	2.3	0.9	2.1	1.9	1.9	1.9	1.8	2.4	2.2	1.8	2.2	2.9
Hypothyroidism/myxoedema (self-reported)	2.1	4.1	11.3	2.6	3.4	3.1	0.9	2.3	2.7	2.4	1.5	0.3	1.3	1.4	1.9	2.3	2.4	1.4	1.1	2.1	2.0	1.7
Hypothyroidism (self reported)	2.0	4.5	12.8	3.0	3.6	2.9	0.9	2.8	3.1	2.2	1.5	-0.2	1.2	1.1	1.7	2.4	2.6	1.3	0.9	2.2	1.9	2.2
Medication: Levothyroxine sodium	2.0	3.4	12.4	2.6	3.5	2.8	1.0	2.2	2.3	2.2	1.4	0.4	1.3	1.2	1.7	2.1	2.1	1.1	0.9	1.8	1.6	1.2
Shortness of breath walking on level ground	2.0	2.4	5.3	2.3	1.8	2.3	0.7	1.1	1.8	1.3	1.7	1.1	1.9	1.7	1.2	2.0	1.7	1.3	1.1	1.1	1.1	2.0
Pulse rate, automated reading	2.0	6.6	11.6	-0.0	0.9	2.8	2.5	2.2	2.9	2.8	2.6	2.6	3.3	3.4	3.1	2.5	2.7	2.8	3.0	2.8	2.7	2.1
Diabetes (mother)	1.9	2.5	11.0	-0.2	-1.2	-2.1	-1.3	-1.3	-1.0	-2.0	-1.1	-3.3	-2.1	-2.1	-1.4	-1.1	-1.6	-1.4	-1.3	-1.5	-1.3	-1.0
Forced expiratory volume in 1-second (FEV1)	1.9	6.5	12.6	-1.9	-2.9	-3.5	-1.8	-2.1	-2.7	-2.7	-2.3	-3.4	-3.2	-3.3	-2.8	-2.5	-2.8	-2.2	-2.0	-2.5	-2.3	-1.8
Age started oral contraceptive pill	1.9	2.4	4.8	-0.6	-0.8	-1.7	-1.9	-1.7	-1.8	-2.2	-1.5	-1.0	-1.2	-1.4	-1.8	-1.6	-1.7	-1.7	-1.5	-1.6	-1.9	-1.5
Blood Red Count	1.8	17.4	66.3	5.6	5.3	4.8	4.6	2.4	5.7	2.8	3.5	8.1	4.5	4.7	2.7	4.3	4.2	2.9	2.0	2.5	2.4	3.4
Mother’s age at death	1.8	2.2	4.0	-1.8	-2.0	-1.9	-1.5	-1.2	-1.5	-1.0	-1.7	-1.7	-1.7	-1.6	-1.3	-1.8	-1.6	-1.1	-1.1	-1.3	-1.2	-1.5
Type 2 Diabetes (T2D) (2012)	1.7	2.0	4.4	1.2	0.5	1.6	1.1	1.2	2.1	1.6	1.7	1.2	1.6	1.6	1.5	1.6	1.6	1.4	1.0	1.1	1.5	1.7
Frequency of depressed mood in last 2 weeks	1.7	2.4	6.4	1.9	1.1	1.5	2.2	2.2	1.4	1.9	1.6	0.4	0.9	0.9	1.1	1.8	1.8	1.5	1.0	1.5	1.6	2.5
Alcohol usually taken with meals	1.7	2.8	6.2	-1.3	-1.1	-1.8	-2.0	-1.0	-1.9	-2.0	-2.1	-1.1	-1.3	-1.3	-1.6	-2.0	-1.9	-1.8	-1.6	-1.8	-1.9	-2.5
Seen a psychiatrist for nerves, anxiety, tension or depression	1.7	2.2	6.4	1.1	0.3	1.6	2.1	-0.0	1.6	2.0	1.6	0.8	0.9	1.0	1.2	1.7	1.6	1.8	1.4	1.4	1.8	2.5
Diabetes diagnosed by doctor	1.7	2.8	5.3	0.7	0.3	1.7	1.7	1.2	2.0	1.9	1.8	0.7	1.6	1.7	2.0	1.8	1.8	2.1	1.7	1.8	2.1	2.3
Major Depression (MDD)	1.6	2.0	3.8	0.9	0.5	1.8	1.5	1.2	1.5	1.9	1.8	-0.1	1.3	1.1	1.4	1.5	1.5	1.5	1.3	1.4	1.5	1.9
Fasting Glucose	1.6	1.9	6.6	0.4	1.0	1.6	1.7	0.5	1.3	1.1	1.3	2.6	1.8	2.0	1.5	1.3	1.3	1.2	1.4	1.2	1.1	0.7
Medication: Metformin	1.6	2.3	4.8	0.6	0.4	0.9	1.9	1.5	1.9	1.6	1.5	0.2	1.2	1.3	1.8	1.6	1.8	1.8	1.6	1.8	1.9	2.2
Past tobacco smoking	1.6	2.9	8.2	-1.6	-0.6	-2.1	-2.3	-1.6	-2.8	-1.6	-1.8	0.3	-0.9	-0.9	-1.5	-2.0	-1.9	-1.6	-1.3	-1.7	-1.8	-2.9
Reproduciblity of spirometry measurement using ERS/ATS criteria	1.6	1.9	4.1	0.4	0.3	0.6	2.0	1.3	1.6	1.1	1.6	1.6	1.4	1.5	1.4	1.5	1.5	1.7	1.6	1.5	1.6	1.6
Number of full sisters	1.6	1.9	4.6	1.3	0.5	1.2	1.8	0.4	1.5	1.2	1.8	1.0	1.5	1.4	1.2	1.8	1.5	1.7	1.3	1.2	1.6	2.1
Illnesses of father: Heart disease	1.6	2.2	3.7	0.9	1.5	1.7	1.5	1.2	1.8	1.9	1.2	1.4	1.3	1.4	1.5	1.4	1.7	1.5	1.4	1.9	1.7	1.7
Depressed Affect (Nagel 2018)	1.5	3.2	8.4	2.4	1.6	2.8	2.2	1.7	1.7	2.1	1.7	-0.1	0.7	0.6	1.3	2.2	2.1	1.6	1.0	1.6	2.0	2.9
Alzheimer’s Disease (in mother)	1.5	1.8	3.5	0.5	-0.4	-0.2	-1.2	-0.7	-1.5	-1.5	-1.5	-0.8	-1.5	-1.7	-1.8	-1.3	-1.4	-1.7	-1.9	-1.6	-1.7	-1.0
Blood Platelet Count	1.5	17.7	43.7	-2.7	-1.2	-2.7	-6.3	-4.1	-4.8	-4.2	-5.3	-2.3	-3.5	-3.2	-3.6	-5.0	-4.6	-4.8	-4.1	-4.4	-4.6	-6.6
Smoking Status	1.5	3.6	9.2	1.8	0.7	3.0	2.6	1.5	2.8	2.0	2.0	0.1	1.0	1.1	1.7	2.2	2.0	1.6	1.4	1.7	1.8	2.9
Impedance of whole body	1.5	7.6	16.0	1.2	3.1	4.0	2.0	3.7	2.7	3.0	2.6	1.9	3.1	3.0	3.1	2.8	3.2	2.6	2.6	3.2	2.8	1.9
Schizophrenia (2018)	1.4	2.8	4.7	-0.1	0.6	0.8	2.1	1.9	1.9	2.0	1.9	1.5	1.8	1.8	1.8	1.7	1.7	2.0	2.2	2.0	1.8	1.5
Heel bone mineral density (BMD) T-score, automated (right)	1.4	3.3	7.8	-1.0	-1.1	-2.8	-1.1	-1.9	-2.2	-2.3	-1.7	0.2	-1.5	-1.5	-1.9	-2.0	-2.2	-1.9	-1.6	-2.1	-2.2	-2.3
Diabetes (self-reported)	1.4	2.2	3.9	0.3	-0.1	1.2	1.6	1.5	1.7	1.8	1.6	0.9	1.5	1.6	1.9	1.5	1.5	1.9	1.5	1.6	1.8	2.0
Falls in the last year	1.4	2.0	3.7	-1.5	-0.6	-0.6	-1.9	-1.4	-1.7	-1.8	-1.9	-0.3	-1.2	-1.1	-1.4	-1.8	-1.4	-1.5	-1.3	-1.2	-1.5	-1.9
Number of full brothers	1.4	1.8	4.9	0.4	0.6	0.7	1.7	1.1	1.6	1.8	1.3	2.2	1.6	1.7	1.4	1.2	1.3	1.5	1.2	1.1	1.4	1.2
Alzheimer’s Disease (including proxy)	1.3	1.8	3.5	0.9	-0.6	0.1	-1.5	-1.3	-1.1	-1.7	-1.4	-1.9	-1.7	-1.7	-1.8	-1.1	-1.2	-1.6	-1.7	-1.6	-1.5	-0.4
Mean Putamen Volume	1.3	1.5	3.8	-0.3	-0.0	1.0	1.4	0.2	0.9	0.8	1.6	0.9	1.8	1.7	1.6	1.5	0.9	1.5	1.9	1.3	1.3	1.1
Hand grip strength (right)	1.3	3.6	8.4	0.5	0.9	1.9	2.0	2.9	1.9	2.3	2.2	-0.9	1.6	1.5	2.2	2.0	2.1	1.9	2.1	2.3	2.1	1.9
Townsend deprivation index at recruitment	1.3	1.8	4.5	1.6	0.9	2.1	1.5	1.9	1.6	1.6	1.2	0.5	0.9	0.8	0.8	1.3	1.6	1.1	0.6	1.3	1.3	2.1
Current tobacco smoking	1.3	2.1	5.7	0.9	0.8	2.4	1.9	0.7	1.5	1.5	1.7	1.0	1.1	1.2	1.4	1.7	1.5	1.4	1.5	1.4	1.5	1.9
Had menopause	1.3	1.6	3.1	0.2	1.2	1.2	1.0	0.5	1.2	1.4	1.3	1.7	1.8	1.7	1.6	1.3	1.2	1.2	1.5	1.5	1.1	0.8
Ever unenthusiastic/disinterested for a whole week	1.3	1.6	4.8	1.9	0.6	1.9	1.6	0.3	1.8	1.4	1.3	0.8	0.6	0.7	0.7	1.6	1.4	1.2	0.7	0.8	1.2	2.2
Smoking status: Current	1.3	2.0	5.4	0.5	0.3	2.3	2.0	0.8	1.6	1.5	1.7	0.4	1.0	1.1	1.5	1.6	1.5	1.5	1.5	1.5	1.6	1.9
Financial situation satisfaction	1.3	1.6	5.0	1.2	0.0	1.5	1.3	-0.4	1.7	1.1	1.6	0.3	1.1	1.1	1.1	1.7	1.3	1.6	1.3	1.0	1.4	2.2
Commuting to job workplace: Public transport	1.3	1.5	2.8	-0.4	-1.3	-0.5	-1.5	-1.3	-1.4	-1.2	-1.5	-1.5	-1.7	-1.4	-1.6	-1.3	-1.2	-0.9	-1.3	-1.3	-1.0	-0.4
Supplements: Fish oil (including cod liver oil)	1.3	1.6	5.3	1.4	2.3	1.4	1.1	1.1	0.8	1.6	1.0	1.4	1.6	1.3	1.4	1.4	1.4	1.0	0.9	1.4	1.1	0.5
Illnesses of father: High blood pressure	1.3	1.6	5.3	-0.3	-0.7	-1.3	-1.4	-2.3	-0.8	-1.6	-1.1	-1.6	-1.6	-1.4	-1.2	-0.9	-1.4	-1.1	-0.9	-1.4	-1.2	-1.1
Irritability	1.3	2.2	9.3	-0.9	-1.7	-1.5	-0.5	-1.9	-1.0	-1.3	-1.1	-3.1	-2.4	-2.3	-1.4	-1.1	-1.4	-1.2	-1.0	-1.2	-1.0	-0.3
Multivitamins +/- minerals	1.2	1.6	3.3	0.3	0.5	0.7	1.6	0.8	1.3	1.8	1.3	1.7	1.2	1.2	1.3	1.3	1.4	1.5	1.4	1.4	1.5	1.3
Hearing difficulty/problems with background noise	1.2	2.0	4.4	-1.7	-1.9	-1.2	-1.0	-0.7	-1.3	-1.4	-1.6	-2.1	-1.9	-1.9	-1.3	-1.7	-1.4	-1.2	-1.1	-0.9	-1.0	-0.9
Pain type(s) experienced in last month: Hip pain	1.2	1.6	4.4	-0.8	-1.3	-0.8	-1.2	-1.5	-0.9	-1.7	-1.2	-2.1	-1.3	-1.3	-1.3	-1.2	-1.4	-1.3	-0.9	-1.2	-1.3	-0.8
Triglycerides	1.1	1.8	3.4	0.2	0.2	1.8	1.0	1.1	1.5	1.7	1.3	0.3	1.5	1.4	1.6	1.3	1.5	1.6	1.5	1.5	1.6	1.8
Arm predicted mass (right)	1.1	5.6	10.1	-0.2	-1.8	-2.2	-1.6	-3.2	-2.4	-2.6	-2.3	-2.0	-3.1	-3.0	-2.9	-2.3	-2.7	-2.5	-2.5	-2.8	-2.6	-1.7
Deep venous thrombosis (DVT) (self-reported)	1.1	1.5	3.0	0.4	0.7	1.4	1.4	1.2	1.0	1.4	1.2	1.7	1.4	1.4	0.9	1.2	1.4	1.2	1.1	1.2	1.1	1.4
Reaction Time	1.0	1.9	7.7	1.3	-0.3	-0.4	2.8	1.3	1.8	1.5	1.5	0.1	0.5	0.6	0.8	1.5	1.4	1.6	1.0	1.1	1.6	2.6
Body Mass Index (BMI) (2010)	1.0	1.3	2.8	1.3	0.4	-0.9	-0.8	-1.7	-1.2	-1.2	-0.9	-0.1	-1.1	-1.2	-1.4	-0.7	-1.2	-1.3	-1.6	-1.7	-1.4	-0.9
Eye problems/disorders: Diabetes related eye disease	1.0	1.1	4.6	-0.3	-0.4	-1.2	-1.3	-0.9	-1.0	-0.7	-1.1	-2.1	-1.2	-1.3	-0.9	-1.0	-0.9	-1.1	-0.9	-0.9	-0.9	-0.8
Impedance of leg (right)	1.0	4.8	10.6	1.1	2.5	3.3	1.7	2.2	2.2	2.3	2.1	1.8	2.5	2.5	2.5	2.3	2.5	2.1	2.0	2.4	2.2	1.5
Fluid intelligence score	1.0	2.1	5.4	-1.5	-1.3	-2.3	-0.8	-0.3	-1.5	-1.8	-1.6	-1.0	-1.5	-1.6	-1.7	-1.8	-1.5	-1.5	-1.2	-1.2	-1.6	-1.5
Depression (self-reported)	1.0	1.2	3.4	0.8	-0.0	1.6	1.0	1.3	1.0	1.4	1.1	0.8	1.2	1.0	0.8	1.1	1.2	1.1	0.7	0.9	1.1	1.8
Qualifications: nursing, teaching	1.0	1.6	2.6	-1.0	-0.6	-0.7	-1.2	-0.8	-1.1	-1.4	-1.6	-1.3	-1.5	-1.5	-1.3	-1.6	-1.3	-1.5	-1.3	-1.1	-1.4	-1.4
Illnesses of father: None of the above (group 1)	1.0	1.2	2.0	-0.5	-0.8	-1.2	-1.2	-0.3	-1.3	-1.2	-1.1	-0.2	-0.8	-1.1	-1.4	-1.3	-1.1	-1.4	-1.3	-1.4	-1.3	-1.3
High cholesterol (Self-reported)	1.0	1.8	13.7	3.7	2.9	2.7	-0.3	0.4	0.9	-0.3	-0.4	0.1	-0.3	-0.4	-0.9	0.5	0.6	-0.6	-1.5	-0.5	-0.4	0.5
Alcohol drinker status: Never	1.0	1.2	3.3	1.0	1.8	0.3	1.4	1.7	1.2	1.3	0.8	1.5	0.7	0.6	0.7	1.0	1.4	0.8	0.6	1.2	1.0	0.7
Schizophrenia (2014)	0.9	2.0	3.5	-0.7	0.5	-0.0	1.7	1.8	1.3	1.6	1.4	1.8	1.6	1.6	1.8	1.1	1.3	1.6	1.9	1.8	1.6	0.7
Medication: Co-codamol	0.9	1.1	2.3	0.5	0.1	-0.3	-1.4	-1.0	-0.6	-0.8	-1.3	-0.7	-1.3	-1.1	-1.3	-1.1	-0.8	-1.4	-1.5	-1.3	-1.2	-1.2
Pain all over the body in last month	0.9	1.0	3.0	1.6	1.3	1.7	1.3	0.3	1.1	1.1	0.8	0.6	0.5	0.5	0.5	1.1	1.1	0.7	0.3	0.8	0.8	1.2
Blood clot in the leg (DVT)	0.9	1.1	2.4	0.6	0.9	1.4	1.1	1.0	0.9	1.2	1.1	1.5	1.3	1.3	0.8	1.1	1.3	1.0	0.8	1.0	0.9	1.2
Arm fat-free mass (right)	0.9	4.7	8.6	-0.0	-1.6	-2.0	-1.4	-2.9	-2.1	-2.3	-2.1	-1.9	-2.9	-2.8	-2.7	-2.1	-2.5	-2.3	-2.4	-2.6	-2.3	-1.4
Comparative body size at age 10	0.9	2.5	4.2	-0.4	-1.1	-2.0	-1.4	-1.5	-1.0	-2.1	-1.6	-0.8	-1.8	-1.8	-2.0	-1.7	-1.8	-1.8	-1.7	-1.8	-1.9	-1.5
Had major operations	0.9	1.1	2.2	-0.8	-0.2	0.5	1.4	0.9	1.2	1.0	1.1	-0.1	0.8	0.8	1.3	0.9	0.9	1.4	1.5	1.4	1.4	1.2
Eye problems/disorders: Cataract	0.9	1.0	2.0	0.5	0.6	0.4	-1.3	-1.4	-0.7	-1.4	-1.0	-0.4	-0.8	-1.1	-1.4	-0.8	-0.9	-1.3	-1.3	-1.1	-1.4	-0.9
Hearing aid user	0.9	1.0	2.5	-1.2	-1.2	-1.2	-0.5	-1.6	-0.9	-1.3	-1.2	0.1	-0.9	-0.8	-1.0	-1.1	-1.2	-1.0	-0.7	-1.0	-1.1	-1.1
Breast Cancer	0.8	2.0	5.4	-2.0	-1.4	-0.3	2.3	1.4	0.4	1.8	1.7	0.3	1.0	1.0	1.7	0.9	0.9	1.8	2.0	1.4	1.8	0.8
Hand grip strength (left)	0.8	2.1	5.7	1.0	1.4	1.2	1.5	2.4	1.3	1.8	1.6	-0.1	1.2	1.1	1.5	1.6	1.7	1.3	1.4	1.7	1.5	1.2
Severe depression (siblings)	0.8	0.9	2.2	1.0	0.8	1.5	1.4	1.1	1.2	1.1	0.7	0.5	0.6	0.5	0.7	0.8	1.1	0.7	0.4	0.8	0.9	1.2
Heel bone mineral density (BMD) T-score, automated (left)	0.8	1.7	4.0	-0.2	-0.5	-1.9	-0.5	-1.8	-1.6	-2.0	-1.1	0.6	-0.9	-0.9	-1.5	-1.3	-1.6	-1.4	-1.2	-1.6	-1.7	-1.5
Hip circumference	0.8	3.6	8.3	2.9	1.2	-0.2	-2.0	-1.6	-1.0	-2.1	-1.7	-1.0	-2.0	-2.1	-2.6	-1.2	-1.5	-2.4	-2.9	-2.4	-2.4	-1.2
Time employed in main current job	0.8	1.0	3.9	-1.5	-0.5	-0.9	-1.8	-0.8	-1.1	-0.9	-1.0	-0.6	-0.4	-0.2	-0.4	-1.0	-1.1	-0.8	-0.3	-0.9	-0.9	-2.0
Breastfed as a baby	0.8	1.0	2.1	1.2	0.6	1.4	1.3	0.2	1.1	1.1	1.3	0.8	0.9	1.1	1.1	1.4	0.9	1.1	0.9	0.5	1.0	1.1
Average weekly beer plus cider intake	0.8	1.2	2.0	0.4	0.3	1.0	-1.4	-1.3	-1.2	-1.0	-1.2	-0.5	-1.4	-1.3	-1.4	-0.9	-1.1	-1.2	-1.3	-1.3	-1.1	-1.1
Verbal and Numeric Reasoning (VNR)	0.7	1.7	3.4	-1.0	-1.0	-1.9	-0.8	-0.3	-1.1	-1.6	-1.4	-1.6	-1.5	-1.7	-1.5	-1.5	-1.3	-1.4	-1.2	-1.0	-1.4	-1.0
Angina	0.7	0.9	4.1	2.0	2.0	0.8	-1.3	-0.3	0.0	-0.7	-0.8	1.5	0.1	0.2	-0.7	-0.1	0.1	-0.8	-1.2	-0.6	-0.8	-0.7
Medication for hormone replacement therapy	0.7	0.8	1.7	-0.7	-0.1	0.3	1.0	1.3	0.6	0.9	0.9	0.6	1.2	1.1	1.2	0.7	0.8	1.1	1.2	1.1	1.0	0.5
Average weekly fortified wine intake	0.7	0.8	2.4	0.2	0.9	0.6	-0.9	0.5	-0.9	-0.3	-0.9	-1.2	-0.9	-1.1	-1.0	-0.9	-0.8	-1.2	-1.1	-0.8	-1.1	-1.6
Tinnitus: Yes, but not now, but have in the past	0.7	0.8	1.5	0.1	-0.4	-0.2	-1.1	-1.2	-0.8	-1.1	-1.0	-1.0	-1.2	-1.2	-1.2	-0.8	-0.8	-0.9	-1.0	-1.0	-0.9	-0.4
Alcohol intake versus 10 years previously	0.7	1.0	2.0	-0.8	-1.1	-1.4	-0.7	-1.1	-0.9	-1.2	-0.8	-1.4	-1.3	-1.4	-0.9	-1.1	-1.1	-0.9	-0.8	-0.9	-0.8	-0.7
Happiness	0.7	0.8	3.9	0.9	-0.3	0.8	1.4	0.7	1.2	0.9	0.9	-0.8	-0.1	-0.0	0.4	1.0	0.9	0.9	0.4	0.6	0.9	2.0
Serious illness, injury or assault of a close relative in last 2 years	0.7	0.8	1.7	-0.2	-0.5	-0.5	-0.9	-0.4	-1.3	-0.8	-0.9	0.1	-0.6	-0.9	-1.2	-1.1	-1.1	-1.1	-1.2	-1.3	-1.3	-0.9
Prospective memory result	0.7	0.8	2.7	0.7	0.8	1.0	1.0	0.0	0.6	0.7	1.0	1.6	1.0	1.1	0.8	1.1	0.9	0.9	0.8	0.7	0.8	0.9
Mouth/teeth dental problems: Bleeding gums	0.7	0.9	2.4	-0.9	-1.4	-0.6	-1.5	-0.6	-1.2	-0.9	-1.1	-0.7	-1.0	-0.7	-0.8	-1.1	-1.0	-0.7	-0.7	-0.9	-0.7	-0.6
Medication: Aspirin	0.7	0.9	5.0	1.1	1.4	2.2	0.2	0.7	1.2	0.4	0.7	-0.5	0.7	0.7	0.7	0.9	1.0	0.7	0.6	1.0	0.8	0.9
Forced expiratory volume in 1-second (FEV1), predicted	0.7	1.5	3.2	1.7	1.6	1.4	1.3	1.8	1.6	1.0	1.1	0.4	0.3	0.6	0.6	1.4	1.6	1.0	0.6	1.2	1.1	1.6
Medication: Aspirin	0.7	0.9	3.9	0.8	1.2	2.0	0.4	1.0	1.1	0.5	0.8	-0.1	0.8	0.8	0.8	0.9	1.1	0.8	0.7	1.1	0.9	1.0
Guilty feelings	0.7	1.0	3.9	-0.6	-0.4	-0.0	1.2	2.0	0.6	1.4	0.9	-0.2	0.5	0.5	1.1	0.6	0.9	1.2	1.2	1.5	1.4	1.0
Supplements: Calcium	0.7	0.8	3.0	-1.5	-1.6	-1.7	-0.7	-1.0	-0.9	-0.4	-0.1	-1.7	-0.7	-0.8	-0.1	-0.5	-1.0	-0.4	0.1	-0.4	-0.3	-0.6
Alcohol drinker status: Previous	0.7	0.8	2.3	-0.5	-0.7	-0.1	1.5	0.1	1.0	0.8	1.0	1.0	0.8	0.9	0.9	0.8	0.7	1.2	1.1	0.9	1.1	1.3
Depression (Nagel 2018)	0.6	0.9	4.0	1.2	0.8	1.2	1.3	2.0	0.8	1.1	0.7	-0.8	-0.1	-0.2	0.4	1.0	1.1	0.7	0.2	0.9	1.0	1.5
HbA1C	0.6	0.7	2.6	-0.0	-0.9	-0.2	-0.2	-1.6	-0.5	-1.2	-0.6	-0.4	-0.9	-1.3	-0.9	-0.7	-0.8	-0.8	-1.2	-0.8	-0.9	-0.0
Pack years adult smoking proportion	0.6	0.9	3.7	0.5	0.6	1.9	1.5	0.7	0.2	0.8	0.9	0.5	1.1	1.1	0.9	1.1	0.8	1.1	1.0	0.8	0.9	0.6
Fed-up feelings	0.6	1.0	6.2	2.5	1.4	2.1	1.0	-0.2	0.8	0.7	0.4	-0.1	-0.4	-0.4	-0.1	1.0	0.8	0.2	-0.3	0.3	0.4	1.6
Waist circumference	0.6	2.3	5.4	1.8	0.5	0.1	-2.1	-1.0	-0.8	-1.8	-1.6	-1.3	-1.6	-1.7	-1.9	-1.2	-1.2	-1.9	-2.3	-1.9	-1.8	-1.1
Financial difficulties in last 2 years	0.6	0.9	4.6	1.1	-0.1	0.1	1.8	-0.0	1.1	0.9	1.2	0.1	0.2	0.1	0.3	1.2	0.9	0.9	0.6	0.7	0.9	2.2
Medication: Simvastatin	0.6	0.9	6.2	0.7	0.3	2.5	0.3	0.6	1.4	0.9	0.7	-1.1	0.4	0.5	0.6	0.7	0.9	0.7	0.4	0.7	0.8	1.2
Pulse rate	0.6	1.1	2.0	0.3	0.4	1.0	1.1	0.9	1.4	1.0	1.0	0.9	1.3	1.3	1.4	1.0	1.1	1.1	1.0	1.2	1.0	1.2
Medication: Cholesterol lowering	0.6	1.0	5.7	2.1	2.0	2.4	-1.1	0.2	0.0	-0.5	-0.4	-0.7	-0.4	-0.4	-0.7	0.1	0.1	-0.8	-1.2	-0.5	-0.6	-0.2
Tense / ‘highly strung’	0.6	1.0	3.1	-0.6	-0.9	-1.1	0.2	-0.4	-1.3	-0.5	-1.0	-1.4	-1.8	-1.6	-1.1	-0.9	-1.1	-1.0	-0.8	-0.9	-0.9	-0.6
Hair/balding pattern: Pattern 4	0.6	1.5	4.9	2.0	2.2	0.6	1.4	0.7	1.1	1.0	1.1	2.1	1.6	1.4	1.0	1.4	1.2	0.8	0.6	0.7	0.6	0.6
Medication for cholesterol, blood pressure or diabetes	0.6	1.0	6.3	-2.2	-2.2	-2.5	-0.3	-0.7	-0.7	-0.3	-0.2	-0.5	-0.3	-0.2	-0.1	-0.7	-0.7	0.1	0.5	-0.2	-0.1	-0.5
Chronic bronchitis/emphysema (mother)	0.6	0.7	2.4	-0.2	0.1	0.7	1.2	1.6	0.4	0.8	0.6	1.0	0.7	0.8	0.8	0.6	0.9	1.0	0.9	1.1	1.0	1.1
Health satisfaction	0.6	0.8	3.9	1.8	0.1	1.6	0.5	-0.6	1.4	0.5	0.9	-0.4	0.4	0.2	0.2	1.2	0.7	0.7	0.3	0.2	0.5	2.0
Angina (self-reported)	0.6	0.8	4.0	1.8	2.0	1.0	-1.3	-0.2	0.1	-0.6	-0.7	1.5	0.2	0.3	-0.5	-0.1	0.2	-0.7	-1.0	-0.4	-0.7	-0.7
Mean time to correctly identify matches	0.6	1.2	5.2	1.2	-0.2	-0.4	2.3	1.1	1.5	1.3	1.0	0.5	0.4	0.4	0.5	1.1	1.1	1.1	0.5	0.8	1.1	2.0
Suffer from ‘nerves’	0.6	1.0	3.0	-0.4	-0.9	-1.1	-0.1	-1.5	-1.7	-0.8	-1.0	0.2	-1.2	-1.1	-1.1	-0.9	-1.3	-0.8	-0.8	-1.2	-1.0	-0.9
Medication: Atorvastatin	0.6	0.8	1.9	0.8	1.1	-0.3	-1.1	-0.8	-1.0	-1.4	-0.8	-0.4	-0.6	-0.7	-0.9	-0.6	-0.7	-1.2	-1.0	-0.9	-1.1	-1.3
Arm fat-free mass (left)	0.6	2.9	5.5	0.7	-0.8	-1.3	-1.1	-2.2	-1.6	-1.9	-1.6	-1.5	-2.3	-2.3	-2.3	-1.5	-1.9	-1.9	-2.0	-2.1	-1.9	-1.0
Pain experienced in last month	0.6	1.0	2.7	-1.6	-0.3	-0.9	0.8	0.7	0.6	1.0	1.1	0.2	1.0	1.3	1.5	0.5	0.5	1.1	1.6	1.1	1.1	-0.4
Arm predicted mass (left)	0.6	2.9	5.3	0.5	-1.0	-1.4	-1.1	-2.3	-1.6	-1.9	-1.6	-1.5	-2.2	-2.2	-2.2	-1.5	-1.9	-1.9	-2.0	-2.1	-1.9	-1.0
Worry (Nagel 2018)	0.5	1.1	4.2	-0.7	-0.9	-2.1	0.2	-0.8	-1.7	-0.5	-0.8	-0.9	-1.8	-1.5	-0.9	-0.8	-1.1	-0.7	-0.5	-0.8	-0.7	-0.6
Ovarian Cancer	0.5	0.6	2.2	-1.4	-0.3	-0.4	0.7	0.5	0.5	0.3	0.5	1.5	1.0	1.0	0.9	0.2	0.5	0.8	1.1	0.9	0.7	0.0
Age at First Birth	0.5	0.7	2.1	-1.4	-1.0	-0.8	-1.3	0.3	-1.3	-0.4	-0.8	-1.4	-0.5	-0.5	-0.3	-1.1	-0.7	-0.4	-0.2	-0.3	-0.3	-1.2
Neuroticism (2016)	0.5	0.7	2.7	1.2	0.3	0.8	1.4	0.5	0.7	1.0	0.9	-0.1	0.2	0.2	0.5	1.1	0.8	0.7	0.3	0.6	0.8	1.6
Heel T-Score	0.5	3.7	8.5	-0.3	-0.4	-1.5	-1.3	-2.6	-1.7	-2.4	-2.0	0.4	-1.7	-1.6	-2.1	-1.9	-2.4	-2.2	-2.0	-2.6	-2.5	-2.9
BMI	0.5	3.0	6.5	1.2	0.4	-0.8	-2.3	-2.5	-1.1	-2.2	-1.7	-1.1	-1.6	-1.6	-1.9	-1.4	-1.8	-2.2	-2.1	-2.2	-2.1	-1.8
Chronotype (morning person)	0.5	1.1	5.3	-0.7	-0.2	0.6	-2.3	-0.6	-1.3	-1.5	-1.1	0.5	0.2	0.1	-0.8	-1.0	-1.0	-1.0	-0.7	-1.1	-1.3	-1.8
Ever had hysterectomy (womb removed)	0.5	0.5	1.9	0.9	0.4	0.4	-0.6	-0.6	-0.2	-1.0	-0.6	-1.4	-0.9	-0.8	-0.8	-0.3	-0.6	-0.9	-0.8	-0.7	-0.9	-0.5
Stomach or abdominal pain in last month	0.5	0.6	3.2	0.7	-0.4	0.8	1.2	0.6	1.3	0.6	0.6	-0.5	0.3	0.3	0.5	0.7	0.9	0.8	0.4	0.7	0.9	1.8
Nervous feelings	0.5	1.0	3.7	-1.1	-1.0	-1.9	-0.1	-0.2	-1.7	-0.2	-0.8	-1.4	-1.5	-1.4	-0.6	-0.9	-1.1	-0.6	-0.3	-0.5	-0.5	-1.0
Forced vital capacity (FVC)	0.5	2.0	7.0	-1.5	-2.2	-1.9	-0.5	-1.2	-1.6	-1.2	-1.0	-2.6	-1.9	-2.0	-1.4	-1.2	-1.4	-0.8	-0.7	-1.1	-0.8	-0.5
Worrier / anxious feelings	0.5	0.9	2.4	0.9	0.7	0.4	1.5	1.3	0.7	1.1	1.1	-0.4	0.2	0.1	0.6	1.2	1.1	0.9	0.8	1.1	1.1	1.6
Loud music exposure frequency	0.5	0.5	4.6	2.1	1.7	1.0	-0.8	-0.6	-0.2	-0.1	-0.0	-0.2	0.0	-0.2	-0.3	0.5	0.1	-0.1	-0.6	-0.4	-0.1	0.3
Headache pain in last month	0.5	0.9	3.0	1.6	0.8	1.4	1.2	0.6	1.2	1.0	0.8	0.4	0.3	0.4	0.4	1.1	1.1	0.8	0.5	0.7	0.8	1.7
Medication: Blood pressure	0.5	0.8	3.9	1.9	2.0	2.0	0.5	0.4	0.5	0.4	0.4	1.2	0.7	0.6	0.3	0.7	0.7	0.1	-0.2	0.3	0.1	0.3
Overall health rating	0.5	1.1	4.9	2.1	1.2	2.2	0.4	0.4	1.3	1.2	0.7	-0.2	0.2	0.2	0.3	1.1	1.1	0.6	-0.1	0.5	0.7	1.8
Knee pain experienced in last month	0.5	0.8	2.3	1.4	0.9	0.6	-1.1	-0.3	-1.0	-0.6	-1.1	0.3	-0.6	-0.8	-1.2	-0.5	-0.4	-1.1	-1.5	-0.9	-1.0	-0.3
Handedness (chirality/laterality): Left-handed	0.5	0.6	1.4	-0.7	-0.2	0.2	0.7	0.6	0.7	0.7	1.0	0.4	0.9	1.1	1.2	0.7	0.8	1.0	1.2	0.9	1.0	0.7
Ever had stillbirth, spontaneous miscarriage or termination	0.5	0.5	2.2	-1.5	-1.0	-0.4	0.9	0.2	0.1	0.6	0.5	0.6	0.6	0.9	1.0	0.2	0.2	0.8	1.3	0.7	0.8	0.1
Medication: Paracetamol	0.5	0.8	3.4	-1.3	-1.3	-0.8	-0.1	-0.4	-0.9	-1.0	-0.6	-1.8	-1.0	-1.2	-0.7	-0.9	-0.9	-0.7	-0.2	-0.4	-0.6	-0.8
Leg fat percentage (left)	0.5	1.7	4.8	2.2	1.5	0.5	-2.0	-1.3	-0.3	-1.4	-1.1	-0.3	-0.8	-0.8	-1.2	-0.7	-0.9	-1.6	-1.9	-1.6	-1.5	-1.4
Fractured/broken bones in last 5 years	0.5	0.6	4.7	-2.2	-1.5	-0.5	-0.4	-0.3	-0.6	0.1	-0.3	-1.6	-0.4	-0.3	0.3	-0.5	-0.5	0.0	0.7	0.1	0.1	-0.5
Cholesterol lowering medication	0.5	0.8	2.0	0.3	0.3	1.3	1.2	0.0	1.4	0.9	0.9	0.5	0.8	0.9	0.8	0.9	1.0	0.9	0.9	1.1	0.9	1.1
Intelligence (Savage-Jansen 2018)	0.4	1.2	3.4	-1.6	-0.8	-1.9	-0.6	0.1	-1.3	-1.2	-1.3	-0.5	-1.1	-1.1	-1.1	-1.5	-1.1	-1.1	-0.7	-0.5	-1.0	-1.3
Neuroticism (Nagel 2018)	0.4	0.9	3.5	0.9	0.2	0.6	1.7	0.9	0.7	1.4	0.9	-0.8	-0.4	-0.4	0.7	1.2	0.9	1.0	0.6	1.0	1.2	1.9
Alzheimer’s Disease (in father)	0.4	0.5	2.0	1.4	0.3	1.1	-0.1	-0.4	1.2	0.2	0.5	-1.0	-0.1	-0.0	-0.1	0.8	0.6	0.4	0.1	0.0	0.4	1.2
Prostate Cancer	0.4	0.6	1.9	0.7	-0.6	-1.4	0.6	-0.1	0.9	0.5	1.2	0.6	0.6	0.8	0.2	0.9	0.7	0.7	0.5	0.1	0.4	1.3
Coronary Artery Disease (CAD)	0.4	0.5	1.4	-0.1	-1.0	-1.2	-0.0	0.0	-0.4	-1.2	-0.5	-1.2	-1.0	-0.8	-0.9	-0.4	-0.9	-0.5	-0.5	-1.0	-0.6	-0.0
Cardiovascular Disease	0.4	1.2	12.4	3.5	1.7	1.6	0.3	-0.2	0.3	-0.3	-0.2	0.1	-0.9	-0.6	-1.1	0.5	0.3	-0.6	-1.4	-0.7	-0.5	1.0
Medication: Atenolol	0.4	0.5	5.1	2.2	1.5	0.4	-0.0	0.5	0.7	0.5	0.0	0.5	-0.1	0.1	0.1	0.6	0.6	0.1	-0.6	0.0	0.3	0.7
Body mass index (BMI)	0.4	1.5	3.6	1.9	0.6	-0.4	-1.7	-1.4	-0.4	-1.4	-1.1	-0.6	-1.1	-1.1	-1.6	-0.8	-1.0	-1.5	-1.8	-1.7	-1.5	-0.9
Impedance of leg (left)	0.4	1.9	6.5	0.4	1.9	2.5	0.7	1.4	1.2	1.2	1.2	1.3	1.7	1.7	1.6	1.3	1.4	1.1	1.2	1.4	1.2	0.3
Medication: Ramipril	0.4	0.6	3.6	1.9	1.8	1.2	0.0	0.1	0.5	0.1	0.4	1.2	0.6	0.6	-0.1	0.7	0.6	0.0	-0.3	0.0	-0.1	0.3
Illnesses of siblings	0.4	0.6	1.8	-0.3	-0.5	-0.9	-1.3	-1.1	-1.0	-0.7	-0.5	-0.4	-0.7	-0.5	-0.8	-0.7	-0.8	-0.8	-0.6	-1.0	-0.8	-1.0
Frequency of tiredness / lethargy in last 2 weeks	0.4	0.7	5.0	1.4	-0.4	1.4	0.6	0.1	1.1	0.5	0.3	-1.2	-0.5	-0.3	-0.0	0.7	0.7	0.5	-0.1	0.3	0.6	2.2
Noisy workplace	0.4	0.5	4.1	1.4	1.4	2.0	-0.5	-0.2	0.0	-0.3	0.1	1.1	0.7	0.4	0.0	0.4	0.1	-0.3	-0.4	-0.3	-0.4	-0.2
Lung cancer (father)	0.4	0.4	3.1	-1.8	-1.1	-1.5	-0.2	-0.6	-0.2	0.1	-0.1	0.2	0.1	0.1	0.2	-0.5	-0.5	0.1	0.4	0.0	0.0	-0.7
Illnesses of mother	0.4	0.5	3.5	-1.3	-1.1	-1.9	-0.4	0.2	-0.6	-0.2	-0.3	-0.3	-0.6	-0.4	-0.4	-0.9	-0.4	-0.4	-0.2	-0.2	-0.2	-0.5
Pulse wave Arterial Stiffness index	0.4	0.4	2.2	1.3	1.3	1.5	0.1	0.7	1.0	0.7	0.5	-0.0	0.2	0.3	0.2	0.6	0.4	-0.0	-0.1	-0.0	0.0	0.1
Seen doctor (GP) for nerves, anxiety, tension or depression	0.4	0.6	3.0	0.7	-0.4	0.6	1.7	0.2	0.4	1.0	0.6	-0.1	-0.3	-0.3	0.1	0.8	0.6	0.7	0.3	0.3	0.8	1.7
Ever highly irritable/argumentative for 2 days	0.4	0.5	1.9	-0.8	-0.4	0.7	1.4	0.7	0.9	0.7	0.7	-0.5	0.0	0.2	0.7	0.6	0.6	0.8	1.0	0.8	0.9	0.6
Birth weight	0.4	0.9	4.2	0.5	0.3	0.7	2.0	0.9	0.6	0.8	1.1	1.7	0.6	0.5	0.6	1.0	0.8	1.0	0.8	0.7	1.0	1.1
Forced vital capacity (FVC), Best measure	0.4	1.5	8.4	-1.1	-1.8	-1.2	-0.5	-1.0	-1.4	-1.0	-0.7	-2.9	-1.7	-1.8	-1.2	-0.8	-1.1	-0.6	-0.5	-0.8	-0.6	-0.0
Number of children fathered	0.4	0.5	1.3	0.7	0.4	0.3	1.1	1.0	0.9	0.5	0.8	1.0	0.7	0.6	0.5	0.8	0.8	0.6	0.4	0.5	0.5	1.1
Neck or shoulder pain in last month	0.4	0.5	2.8	1.7	1.5	1.3	-0.2	0.2	0.6	0.0	-0.2	1.1	0.2	-0.2	-0.4	0.3	0.4	-0.5	-0.7	-0.1	-0.3	0.7
Medication: Ibuprofen	0.4	0.4	3.0	-1.0	-1.7	-1.4	0.1	-0.3	-0.6	-0.5	-0.1	-1.0	-0.3	-0.5	-0.2	-0.4	-0.6	0.1	0.2	-0.2	-0.1	0.2
Smoking status: Previous	0.4	0.6	2.9	1.3	0.1	0.8	1.1	0.7	1.6	0.6	0.6	-0.7	-0.0	-0.1	0.4	0.8	0.8	0.5	0.2	0.5	0.6	1.7
Loneliness, isolation	0.4	0.5	2.9	0.9	-0.5	1.3	0.9	0.4	0.1	1.0	0.6	0.2	-0.0	-0.1	0.0	0.7	0.6	0.7	0.1	0.2	0.7	1.7
Whole body water mass	0.4	2.0	4.4	0.5	-1.0	-1.3	-0.7	-1.8	-1.5	-1.4	-1.3	-1.5	-2.1	-2.1	-1.9	-1.2	-1.5	-1.4	-1.6	-1.7	-1.4	-0.6
Average weekly champagne plus white wine intake	0.4	0.5	1.3	-0.5	-0.3	-0.9	-0.9	0.2	-1.0	-1.1	-0.6	-0.8	-0.3	-0.3	-0.7	-0.7	-0.7	-0.6	-0.6	-0.8	-0.8	-1.0
Number of operations (self-reported)	0.4	0.6	2.8	0.9	0.3	1.3	0.8	-0.1	1.2	0.4	0.8	-0.5	0.3	0.4	0.6	0.9	0.7	0.7	0.7	0.8	0.7	1.7
Commuting to job workplace: Cycle	0.4	0.5	1.7	0.1	-0.7	-1.3	-0.2	0.1	-0.5	-0.9	-0.9	-0.0	-1.0	-0.9	-0.9	-0.8	-0.6	-0.6	-1.0	-0.7	-0.7	-0.0
Pack years of smoking	0.4	0.6	2.9	0.3	0.6	1.7	1.2	0.5	-0.2	0.6	0.6	0.6	0.9	0.9	0.7	0.8	0.5	0.8	0.8	0.5	0.6	0.1
Leg fat mass (left)	0.4	1.5	4.2	2.0	1.1	0.3	-1.6	-1.4	-0.4	-1.3	-1.1	-0.5	-1.0	-1.0	-1.3	-0.7	-0.9	-1.5	-1.8	-1.6	-1.4	-1.1
Hearing difficulty/problems: Yes	0.3	0.5	3.2	-1.8	-1.2	-0.5	-0.4	-0.6	-0.4	-0.6	-0.7	-0.5	-0.8	-0.6	-0.2	-0.9	-0.6	-0.3	0.0	0.0	-0.2	-0.4
Supplements: Zinc	0.3	0.3	2.4	0.5	-1.0	0.1	0.8	0.2	0.2	-0.1	0.7	-0.6	-0.1	-0.1	-0.0	0.6	0.3	0.5	0.4	0.2	0.3	1.5
Maternal smoking around birth	0.3	0.4	0.9	-0.9	-0.7	0.5	0.4	0.3	0.7	0.6	0.4	0.5	0.6	1.0	0.7	0.3	0.7	0.9	0.9	0.7	0.9	0.7
Frequency of unenthusiasm / disinterest in last 2 weeks	0.3	0.4	1.6	0.8	0.2	1.0	0.2	1.1	-0.1	-0.2	-0.3	-1.3	-0.8	-0.8	-0.5	0.1	0.1	-0.4	-0.6	-0.2	-0.2	0.5
Bilateral oophorectomy (both ovaries removed)	0.3	0.3	0.8	-0.8	-0.4	-0.6	0.1	-0.5	-0.5	-0.9	-0.5	-0.8	-0.6	-0.7	-0.2	-0.5	-0.7	-0.6	-0.1	-0.2	-0.5	-0.7
Hair/balding pattern: Pattern 2	0.3	0.4	1.6	-0.8	-0.9	-0.0	1.3	0.6	0.1	0.1	0.6	-0.3	0.1	0.1	0.5	0.3	0.4	0.8	0.8	0.7	0.8	1.0
Mouth/teeth dental problems	0.3	0.5	2.0	-1.4	-0.7	-0.9	0.9	0.5	0.1	0.4	0.8	-0.6	0.5	0.4	0.9	0.4	0.3	0.8	1.2	0.9	0.7	0.3
Neuroticism score	0.3	0.6	2.7	0.9	-0.2	-0.1	1.5	0.3	-0.1	0.5	0.4	-1.6	-1.1	-1.1	-0.2	0.5	0.2	0.2	-0.0	0.2	0.4	1.4
Weight	0.3	1.3	3.8	1.9	0.6	0.1	-1.1	-1.1	-0.5	-1.1	-0.9	-0.9	-1.4	-1.4	-1.5	-0.6	-0.9	-1.3	-1.7	-1.4	-1.2	-0.4
Arm fat percentage (right)	0.3	1.1	8.5	2.9	2.6	1.6	-0.7	0.9	1.1	0.3	0.3	0.1	0.3	0.3	0.1	0.7	0.8	-0.2	-0.6	0.1	0.1	0.2
Trunk fat-free mass	0.3	1.8	4.2	0.4	-1.1	-1.1	-0.4	-1.9	-1.4	-1.2	-1.1	-1.4	-2.0	-2.0	-1.8	-1.1	-1.4	-1.2	-1.4	-1.5	-1.2	-0.3
Medication: Ibuprofen (e.g. Nurofen)	0.3	0.4	2.1	-0.7	-1.4	-0.7	0.7	-0.0	-0.1	0.3	0.7	-0.8	0.2	-0.0	0.3	0.4	0.2	0.8	0.8	0.5	0.7	1.2
Trunk predicted mass	0.3	1.8	4.2	0.4	-1.1	-1.1	-0.4	-1.9	-1.4	-1.3	-1.1	-1.4	-2.1	-2.0	-1.8	-1.1	-1.5	-1.3	-1.5	-1.6	-1.3	-0.4
Exposure to tobacco smoke at home	0.3	0.3	1.5	0.9	1.2	0.9	0.1	0.7	-0.1	0.6	0.3	-0.2	0.2	0.4	0.5	0.6	0.7	0.3	0.3	0.8	0.7	0.2
Peak expiratory flow (PEF)	0.3	0.6	1.6	-0.6	-0.8	-1.2	1.1	1.3	0.8	0.3	0.6	-1.0	-0.2	-0.2	0.5	0.4	0.6	0.7	0.8	0.9	0.8	1.1
Leg fat percentage (right)	0.3	1.1	6.6	2.6	1.9	1.0	-1.5	-0.8	0.3	-0.8	-0.6	-0.1	-0.4	-0.4	-0.7	-0.1	-0.3	-1.1	-1.4	-1.0	-0.9	-0.8
Worry too long after embarrassment	0.3	0.5	2.5	-1.2	-1.6	-0.8	1.0	0.2	-0.2	0.5	0.3	-1.3	-0.7	-0.5	0.2	-0.0	0.0	0.5	0.6	0.6	0.6	0.9
Pulse wave peak to peak time	0.3	0.4	1.9	-1.3	-1.3	-1.4	0.1	-0.7	-0.9	-0.6	-0.4	0.1	-0.1	-0.2	-0.0	-0.5	-0.3	0.2	0.3	0.2	0.1	-0.0
Medication for pain relief, constipation, heartburn	0.3	0.4	3.0	-0.5	0.1	-1.7	-0.3	-0.1	-0.5	0.0	-0.6	1.2	-0.2	0.0	-0.2	-0.6	-0.5	-0.4	-0.5	-0.6	-0.4	-1.3
Leg fat mass (right)	0.3	1.0	4.8	2.2	1.2	0.6	-1.4	-1.0	-0.1	-0.9	-0.8	-0.4	-0.8	-0.7	-1.0	-0.4	-0.6	-1.2	-1.5	-1.2	-1.1	-0.8
Comparative height size at age 10	0.3	1.6	11.2	1.0	1.6	3.3	1.7	1.5	0.8	1.2	0.7	1.0	0.7	0.6	0.9	1.0	1.1	0.9	0.6	1.2	1.1	0.9
Qualifications: NVQ or HND or HNC or equivalent	0.3	0.3	1.4	1.2	1.1	0.6	0.6	0.6	0.5	0.5	0.9	-0.5	0.3	0.2	0.3	0.8	0.6	0.3	0.2	0.4	0.4	0.5
Hypertension (Self-reported)	0.3	0.9	6.0	2.5	1.2	1.2	1.1	0.5	1.3	0.9	0.7	0.6	0.0	0.3	0.1	1.0	1.0	0.4	-0.2	0.3	0.5	1.6
Illnesses of siblings: Diabetes	0.3	0.4	2.8	1.7	1.2	1.1	0.1	-0.3	0.5	0.3	-0.0	1.0	0.3	0.3	0.1	0.4	0.4	0.0	-0.4	-0.2	0.0	0.2
Whole body fat-free mass	0.3	1.8	4.1	0.6	-0.9	-1.1	-0.6	-1.8	-1.4	-1.3	-1.2	-1.3	-2.0	-2.0	-1.8	-1.1	-1.5	-1.4	-1.6	-1.6	-1.3	-0.5
Leg fat-free mass (right)	0.3	1.7	3.7	0.6	-0.9	-1.0	-0.8	-1.4	-1.3	-1.4	-1.1	-1.5	-1.9	-1.9	-1.8	-1.1	-1.3	-1.3	-1.6	-1.6	-1.3	-0.4
Mood swings	0.3	0.6	3.1	1.8	0.9	1.2	0.8	0.9	0.5	0.8	0.5	-0.6	-0.4	-0.4	-0.1	0.8	0.8	0.3	-0.2	0.3	0.6	1.2
Back pain experienced in last month	0.3	0.4	1.6	0.1	-0.4	-0.0	-1.0	-0.3	-0.3	-0.9	-0.7	-1.3	-0.6	-0.9	-0.8	-0.6	-0.5	-0.8	-0.8	-0.5	-0.8	0.4
Osteoporosis (self-reported)	0.3	0.3	1.9	-0.5	-0.1	-1.4	-0.7	-0.2	-0.9	-0.4	-0.6	-0.5	-0.5	-0.6	-0.3	-0.5	-0.5	-0.6	-0.3	-0.2	-0.4	-0.9
Osteoarthritis (self-reported)	0.3	0.4	1.7	-0.9	-0.7	-0.2	-0.4	-1.2	-0.9	-0.4	-0.4	1.3	0.5	0.2	-0.3	-0.6	-0.8	-0.4	-0.1	-0.6	-0.7	-0.8
Medication: Gliclazide	0.3	0.3	1.6	-1.3	-0.9	-0.7	0.4	-0.2	0.0	-0.2	0.3	1.1	0.5	0.5	0.3	-0.0	0.1	0.5	0.8	0.4	0.4	0.3
Leg predicted mass (right)	0.3	1.8	3.8	0.6	-0.9	-1.1	-0.9	-1.4	-1.4	-1.4	-1.2	-1.5	-2.0	-2.0	-1.9	-1.2	-1.4	-1.4	-1.6	-1.6	-1.3	-0.5
Tinnitus: Yes, now most or all of the time	0.3	0.3	1.0	0.2	1.0	-0.1	0.7	0.2	0.2	0.7	0.6	-0.1	0.6	0.5	0.9	0.6	0.4	0.4	0.7	0.8	0.5	0.1
Medication: Bendroflumethiazide	0.3	0.5	2.4	1.1	1.0	1.3	0.8	0.1	0.8	0.2	0.5	1.6	0.7	0.6	0.4	0.7	0.5	0.4	0.1	0.3	0.2	0.6
Basal metabolic rate	0.3	1.5	3.4	1.0	-0.5	-0.8	-0.6	-1.5	-1.1	-1.2	-1.0	-1.3	-1.8	-1.8	-1.7	-0.9	-1.2	-1.3	-1.6	-1.5	-1.3	-0.4
Risk taking	0.3	0.4	1.0	-0.8	-0.6	0.2	-0.6	-0.6	-0.5	-0.2	-1.0	-0.6	-1.0	-0.8	-0.7	-0.8	-0.5	-0.5	-0.6	-0.5	-0.3	-0.3
Diastolic blood pressure, automated reading	0.3	0.9	2.7	1.0	-0.3	-0.1	-0.7	-0.7	-0.4	-0.5	-1.2	0.3	-1.2	-1.1	-1.4	-1.0	-0.7	-1.2	-1.6	-1.3	-1.1	-0.5
Vascular/heart problems diagnosed by doctor	0.3	0.7	5.1	-2.2	-1.3	-1.2	-0.6	-0.2	-1.0	-0.6	-0.3	-0.8	0.2	-0.2	0.1	-0.7	-0.8	-0.2	0.5	-0.1	-0.3	-1.1
Medication: Omeprazole (e.g. Zanprol)	0.3	0.3	1.6	0.9	0.7	1.3	-0.2	0.6	0.9	0.3	0.0	-0.5	0.1	0.2	0.3	0.4	0.7	0.3	-0.0	0.5	0.5	0.7
Heart disease (siblings)	0.3	0.4	1.5	1.2	1.1	0.6	1.2	-0.1	0.6	0.2	0.3	1.1	0.4	0.3	0.2	0.6	0.5	0.2	0.1	0.3	0.2	1.0
Height	0.2	3.5	10.2	-0.4	0.5	3.2	2.9	2.5	-0.2	2.6	1.9	-0.1	0.9	0.9	1.7	1.6	1.6	2.1	2.1	2.4	2.4	1.8
Systolic Blood Pressure	0.2	0.8	4.0	2.0	1.6	1.4	0.6	1.9	0.5	1.1	0.3	0.4	0.0	0.0	0.3	0.6	0.8	0.1	-0.3	0.4	0.4	0.4
Neuroticism	0.2	0.6	2.7	1.0	-0.0	-0.0	1.6	0.7	0.1	0.6	0.6	-1.1	-0.8	-0.7	-0.0	0.8	0.5	0.5	0.2	0.5	0.7	1.6
Average weekly spirits intake	0.2	0.3	1.7	0.6	-0.2	1.3	-0.2	1.0	0.3	0.4	-0.1	-0.6	-0.1	-0.1	-0.1	0.1	0.6	0.2	-0.2	0.3	0.4	1.2
Other serious medical condition/disability diagnosed by doctor	0.2	0.2	2.0	0.5	0.9	1.4	0.0	-0.7	0.3	0.4	-0.1	0.4	0.5	0.3	0.1	0.2	0.2	-0.1	0.1	0.1	-0.1	-0.2
Ever used hormone-replacement therapy (HRT)	0.2	0.3	2.7	0.2	-0.7	0.1	0.8	0.0	0.4	-0.4	0.6	-0.1	0.3	0.0	0.2	0.5	0.3	0.4	0.4	0.5	0.3	1.6
Systolic blood pressure, automated reading	0.2	0.5	1.5	0.9	0.9	0.6	-0.7	-0.2	-0.6	0.0	-0.9	0.2	-0.7	-0.7	-0.7	-0.6	-0.5	-1.1	-1.1	-0.9	-0.8	-1.2
Trunk fat percentage	0.2	0.9	6.2	2.5	2.5	1.5	-0.9	0.5	0.7	0.0	0.0	0.4	0.3	0.2	-0.1	0.4	0.4	-0.4	-0.7	-0.2	-0.2	-0.4
Relative age voice broke	0.2	0.3	0.7	-0.1	0.0	0.7	0.8	0.6	0.5	0.2	0.7	0.1	0.8	0.7	0.5	0.7	0.7	0.8	0.8	0.6	0.6	0.6
Qualifications: CSEs or equivalent	0.2	0.2	2.2	1.5	0.4	0.6	0.1	-0.2	0.6	0.0	0.3	0.4	0.1	0.1	-0.3	0.4	0.4	0.1	-0.4	-0.3	-0.0	0.7
High blood pressure	0.2	0.5	4.3	2.1	1.1	0.9	0.6	0.1	0.9	0.7	0.2	0.7	-0.3	0.1	-0.1	0.6	0.7	0.0	-0.5	-0.0	0.2	0.9
Trunk fat mass	0.2	0.8	5.7	2.4	1.9	0.9	-1.0	-0.1	0.2	-0.4	-0.4	-0.1	-0.4	-0.4	-0.7	-0.0	-0.1	-0.8	-1.1	-0.7	-0.6	-0.6
Frequency of tenseness / restlessness in last 2 weeks	0.2	0.3	1.3	-0.2	-1.1	-0.3	0.2	-0.0	-1.0	-0.6	-0.5	-0.6	-0.8	-0.8	-0.7	-0.4	-0.6	-0.4	-0.5	-0.6	-0.4	0.4
Hair/balding pattern: Pattern 3	0.2	0.3	0.9	0.5	0.5	0.9	0.2	0.0	0.8	0.6	0.7	0.4	0.8	0.7	0.6	0.8	0.6	0.5	0.5	0.4	0.4	0.5
Qualifications: A levels/AS levels or equivalent	0.2	0.5	1.9	-0.6	0.1	-1.1	0.7	1.4	0.5	0.7	0.3	-0.5	-0.0	0.0	0.5	0.3	0.7	0.7	0.6	1.1	0.9	0.6
Medication: Lansoprazole	0.2	0.2	1.3	-0.9	-0.6	1.2	0.0	-0.7	-0.2	0.1	-0.0	-0.4	0.2	0.1	0.4	-0.0	-0.1	0.3	0.5	0.3	0.4	-0.0
Arm fat mass (right)	0.2	0.9	6.1	2.5	1.7	0.6	-1.2	-0.3	0.1	-0.7	-0.5	-0.5	-0.7	-0.7	-0.9	-0.2	-0.3	-1.1	-1.4	-0.9	-0.9	-0.4
Length of working week for main job	0.2	0.2	1.5	0.3	0.0	0.3	0.0	1.2	0.8	0.6	0.3	-0.0	0.4	0.4	0.6	0.4	0.4	0.3	0.3	0.4	0.3	0.4
Medication: Amlodipine	0.2	0.3	1.5	0.1	-0.4	0.5	-0.5	0.6	-0.1	-0.5	-0.4	-1.2	-0.5	-0.6	-0.5	-0.4	-0.3	-0.5	-0.6	-0.4	-0.5	0.1
High blood pressure (siblings)	0.2	0.3	1.3	-1.0	-1.0	-0.5	0.8	0.5	0.3	-0.1	0.1	-1.1	-0.3	-0.3	0.2	-0.1	0.0	0.4	0.4	0.5	0.4	0.5
Body fat percentage	0.2	0.7	5.3	2.3	2.1	1.2	-1.1	0.1	0.5	-0.2	-0.2	0.0	0.0	0.0	-0.3	0.2	0.2	-0.6	-0.8	-0.4	-0.4	-0.5
Migraine (self-reported)	0.2	0.2	1.3	1.1	1.0	0.4	0.1	0.6	0.0	0.7	0.1	0.8	0.1	0.1	0.0	0.3	0.3	0.1	-0.2	0.2	0.1	0.3
Whole body fat mass	0.2	0.8	4.3	2.1	1.5	0.7	-1.1	-0.5	0.0	-0.7	-0.5	-0.2	-0.6	-0.5	-0.8	-0.2	-0.3	-1.0	-1.2	-0.9	-0.8	-0.6
Leg pain on walking	0.2	0.2	0.9	0.6	0.5	0.2	0.1	-0.9	0.5	0.2	0.3	0.9	0.4	0.2	0.0	0.5	0.2	0.2	0.1	-0.1	0.1	0.8
Illness, injury, bereavement, stress in last 2 years	0.2	0.2	1.1	-0.7	-0.3	0.3	-0.6	0.7	0.3	0.0	-0.0	-1.1	0.4	0.4	0.5	-0.2	0.0	0.0	0.4	0.4	0.1	-0.4
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.2	0.3	2.0	0.2	0.8	0.9	-0.5	0.4	0.3	-0.1	-0.4	-1.4	-0.8	-0.7	-0.0	-0.2	0.1	-0.5	-0.3	0.3	-0.1	-0.1
Arm fat percentage (left)	0.2	1.0	7.8	2.8	2.5	1.4	-0.6	0.7	1.0	0.3	0.4	0.2	0.3	0.3	0.1	0.7	0.7	-0.2	-0.5	0.1	0.1	0.2
Mineral and other dietary supplements	0.2	0.3	2.9	-1.1	-1.7	-0.7	0.2	-0.2	0.2	-0.4	0.0	0.1	-0.2	0.1	-0.2	-0.3	-0.2	0.2	0.2	-0.2	0.0	0.5
Breast cancer (self-reported)	0.2	0.2	1.3	1.2	1.0	0.1	-0.2	-0.5	0.5	0.3	-0.0	1.1	0.1	0.1	-0.2	0.2	0.3	-0.1	-0.4	-0.2	-0.1	-0.0
Arm fat mass (left)	0.2	0.9	6.2	2.5	1.7	0.6	-1.1	-0.4	0.1	-0.7	-0.5	-0.5	-0.7	-0.7	-0.9	-0.1	-0.3	-1.1	-1.3	-0.9	-0.9	-0.5
Ever taken oral contraceptive pill	0.2	0.2	1.0	1.0	-0.6	-0.1	0.1	0.1	0.2	-0.5	0.1	-0.6	-0.2	-0.3	-0.7	0.1	-0.0	-0.1	-0.6	-0.5	-0.3	0.7
Medication: Blood pressure	0.2	0.3	1.4	1.2	-0.1	0.5	0.9	0.4	0.9	0.5	0.2	0.6	-0.2	0.0	-0.1	0.3	0.6	0.3	-0.3	0.1	0.3	1.2
Ever had prostate specific antigen (PSA) test	0.2	0.2	1.0	1.0	0.7	0.3	0.6	0.1	0.3	0.1	0.3	1.0	0.2	0.0	-0.2	0.5	0.3	0.1	-0.1	0.0	-0.0	0.4
LDL Cholesterol	0.1	0.2	0.8	0.6	0.3	0.9	-0.8	-0.6	-0.5	-0.3	-0.3	-0.5	0.1	-0.0	-0.2	-0.2	-0.3	-0.3	-0.5	-0.5	-0.4	-0.3
Waist Hip Ratio (WHR)	0.1	0.6	4.0	-1.7	-2.0	-0.0	-0.5	0.8	-0.7	-0.3	-0.7	-1.5	-0.5	-0.5	-0.1	-0.8	-0.1	0.1	-0.1	0.1	0.4	0.4
Hair Pigment	0.1	1.5	12.4	-2.6	-3.5	0.9	0.6	-1.2	-0.4	0.1	0.3	-2.4	-0.2	-0.2	0.2	-0.2	-0.3	0.6	0.7	0.2	0.6	0.9
Tanning	0.1	1.6	3.7	-0.4	1.1	1.9	1.3	0.9	1.2	1.5	1.1	0.6	1.0	1.2	1.6	1.2	1.5	1.3	1.6	1.7	1.6	0.7
Sensitivity / hurt feelings	0.1	0.2	1.4	0.5	0.3	0.1	1.2	0.8	0.7	0.4	0.4	0.3	-0.1	0.0	0.3	0.5	0.4	0.4	0.3	0.5	0.4	0.6
Relative age of first facial hair	0.1	0.2	0.4	0.1	0.1	-0.2	0.7	0.6	0.3	0.0	0.5	-0.2	0.1	0.2	0.4	0.5	0.5	0.6	0.6	0.6	0.7	0.6
Leg fat-free mass (left)	0.1	0.7	1.9	1.3	-0.3	-0.4	-0.3	-0.8	-0.6	-0.6	-0.6	-1.1	-1.4	-1.4	-1.2	-0.4	-0.7	-0.7	-1.1	-0.9	-0.7	0.3
Supplements: Glucosamine	0.1	0.1	0.5	0.7	0.6	0.6	-0.1	0.0	0.2	0.3	0.2	-0.5	0.1	-0.1	-0.1	0.3	0.1	-0.1	-0.1	-0.1	-0.1	-0.2
Diverticular disease/diverticulitis (self-reported)	0.1	0.1	0.8	-0.5	-0.1	-0.2	0.5	0.9	-0.1	-0.0	-0.2	0.6	0.2	0.1	0.1	-0.2	0.1	0.1	0.1	0.2	0.1	0.2
Sitting height	0.1	0.8	2.5	-0.7	-1.2	-0.9	0.5	-0.7	-1.2	-0.7	-0.6	-0.8	-1.4	-1.6	-1.1	-0.9	-1.1	-0.8	-0.8	-0.9	-0.8	-0.4
High blood pressure (mother)	0.1	0.1	0.7	-0.1	0.5	0.8	0.4	-0.7	0.4	-0.3	-0.1	0.2	-0.3	-0.2	-0.1	0.2	0.0	0.1	0.1	0.0	-0.0	-0.1
Leg predicted mass (left)	0.1	0.8	2.0	1.2	-0.4	-0.5	-0.3	-0.9	-0.7	-0.7	-0.6	-1.1	-1.4	-1.4	-1.3	-0.5	-0.7	-0.8	-1.1	-1.0	-0.7	0.2
Had other major operations	0.1	0.1	0.3	-0.2	0.0	0.3	0.1	-0.1	0.2	0.2	0.3	0.3	0.1	0.2	0.4	0.3	0.2	0.3	0.6	0.5	0.3	0.4
Pulse wave reflection index	0.1	0.2	0.4	-0.5	-0.0	-0.2	-0.5	0.2	-0.4	-0.4	-0.3	-0.5	-0.5	-0.4	-0.5	-0.5	-0.3	-0.5	-0.3	-0.4	-0.4	-0.6
Qualifications: O levels/GCSEs or equivalent	0.1	0.2	0.7	0.8	0.8	-0.7	0.1	0.5	0.6	0.6	0.2	-0.5	-0.3	-0.1	0.0	0.4	0.3	-0.0	-0.0	0.3	0.1	0.2
Medication: Paracetamol	0.1	0.2	1.6	-0.8	-0.5	0.4	0.5	0.1	-0.1	-0.2	0.3	-1.3	-0.2	-0.4	0.1	0.1	0.0	0.1	0.6	0.4	0.1	0.2
Age at first live birth	0.1	0.1	0.3	-0.1	0.2	0.6	-0.6	0.4	-0.5	0.1	-0.1	0.0	0.3	0.5	0.2	-0.1	0.0	0.2	0.1	0.1	0.1	-0.5
Mouth/teeth dental problems: Loose teeth	0.1	0.1	0.7	0.6	-0.2	0.8	0.1	-0.2	0.3	-0.3	0.2	-0.6	0.0	0.0	-0.1	0.2	0.1	0.0	-0.1	-0.1	-0.0	0.5
Medication: Omeprazole	0.1	0.1	0.5	0.1	0.1	0.7	-0.4	0.1	0.1	-0.3	-0.5	-0.7	-0.2	-0.4	-0.1	-0.2	0.1	-0.2	-0.4	0.1	0.0	0.2
Age at last live birth	0.1	0.1	0.4	0.5	0.5	0.3	-0.1	0.6	-0.1	0.5	0.0	0.4	0.2	0.5	0.2	0.3	0.4	0.5	0.2	0.2	0.4	0.2
Commuting to job workplace: Car/motor vehicle	0.1	0.1	0.3	0.5	0.3	-0.1	-0.1	-0.4	0.0	-0.2	0.6	0.2	0.6	0.3	-0.0	0.4	0.0	0.0	0.2	-0.1	-0.1	0.0
Commuting to job workplace: Walk	0.1	0.1	0.4	-0.1	0.6	-0.2	0.1	0.5	0.1	0.1	-0.1	0.4	0.2	0.1	0.4	0.1	0.2	0.1	0.1	0.5	0.2	-0.2
Medication for cholesterol	0.1	0.2	0.6	0.0	0.3	-0.3	-0.7	-0.8	-0.5	-0.4	-0.3	-0.2	-0.3	-0.3	-0.4	-0.2	-0.5	-0.4	-0.3	-0.5	-0.4	-0.8
Eye problems/disorders: Glaucoma	0.1	0.1	0.5	0.7	-0.0	0.1	-0.2	-0.2	-0.2	-0.1	-0.2	0.1	0.1	-0.1	-0.2	-0.2	-0.2	-0.2	-0.4	-0.3	-0.2	0.1
Age when periods started (menarche)	0.0	0.1	1.0	-0.0	-0.4	0.2	-0.1	-1.0	-0.4	0.3	0.3	-0.4	0.1	0.2	-0.1	0.2	-0.1	0.2	0.2	-0.2	0.1	-0.0
Standing height	0.0	0.2	1.2	0.1	0.1	1.1	1.1	0.4	-0.4	0.5	0.2	-0.5	-0.6	-0.6	-0.1	0.2	0.2	0.2	0.1	0.4	0.4	0.7
Glaucoma (self-reported)	0.0	0.1	0.6	0.8	0.3	-0.2	-0.4	-0.1	-0.1	-0.1	0.1	0.0	0.2	0.1	-0.1	0.1	-0.0	-0.0	-0.2	-0.2	-0.1	0.3
Unable to work because of sickness or disability	0.0	0.1	0.2	-0.1	0.0	0.3	0.4	0.0	0.3	0.4	-0.0	-0.3	-0.4	-0.1	0.1	0.1	0.1	0.1	0.2	0.2	0.3	0.2

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