[Hub]/) : Traits : Number of self-reported non-cancer illnesses :

chr15:66,797,492-68,789,191

Best TWAS P=2e-09 · Best GWAS P=7.08e-11 conditioned to 0.000585

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex AAGAB 0.06 0.05 enet 11 0.05 3.2e-07 -5.3 -5.7 1.4e-08 0.67 0.05 0.95 FALSE
2 GTEx Brain Cerebellum MAP2K5 0.27 0.12 lasso 5 0.14 7.9e-05 -6.0 5.6 1.8e-08 -0.67 0.06 0.89 FALSE
3 The Cancer Genome Atlas Bladder Urothelial Carcinoma IQCH 0.13 0.07 blup 112 0.10 5.2e-09 -4.3 5.4 5.5e-08 -0.48 0.12 0.88 FALSE
4 The Cancer Genome Atlas Breast Invasive Carcinoma IQCH 0.06 0.05 blup 112 0.06 5.2e-12 -6.1 6.0 2.0e-09 -0.65 0.04 0.96 TRUE
5 The Cancer Genome Atlas Colon Adenocarcinoma IQCH 0.08 0.02 blup 111 0.05 4.2e-04 -4.2 5.8 8.9e-09 -0.61 0.10 0.79 FALSE
6 The Cancer Genome Atlas Brain Lower Grade Glioma IQCH 0.05 0.04 blup 111 0.04 7.7e-06 -4.3 5.5 4.1e-08 -0.58 0.13 0.85 FALSE
7 The Cancer Genome Atlas Ovarian Serous Cystadenocarcinoma IQCH 0.11 0.10 blup 112 0.10 2.3e-07 -2.5 5.3 1.4e-07 -0.61 0.34 0.65 FALSE
8 The Cancer Genome Atlas Pancreatic Adenocarcinoma IQCH 0.35 0.04 blup 112 0.12 1.5e-05 -4.3 5.7 9.6e-09 -0.46 0.09 0.82 FALSE