Best TWAS P=4.65e-10 · Best GWAS P=6.84e-12 conditioned to 0.000234
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | ATXN2 | 0.02 | 0.03 | enet | 8 | 0.02 | 4.8e-04 | -3.7 | 5.1 | 2.6e-07 | 0.57 | 0.23 | 0.69 | FALSE |
| 2 | GTEx | Artery Tibial | HECTD4 | 0.05 | 0.02 | lasso | 3 | 0.01 | 3.1e-02 | 5.6 | 5.4 | 5.6e-08 | 0.81 | 0.02 | 0.91 | FALSE |
| 3 | YFS | Blood | SH2B3 | 0.05 | 0.01 | enet | 22 | 0.02 | 3.3e-07 | -4.3 | 6.2 | 4.6e-10 | 0.66 | 0.42 | 0.58 | TRUE |