Best TWAS P=8.64e-08 · Best GWAS P=3.28e-09 conditioned to 0.00313
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Thyroid | NRBF2 | 0.11 | 0.05 | lasso | 3 | 0.07 | 2.5e-06 | -3.3 | -5.1 | 3.0e-07 | -0.53 | 0.69 | 0.14 | FALSE |
2 | The Cancer Genome Atlas | Pancreatic Adenocarcinoma | NRBF2 | 0.18 | 0.13 | enet | 11 | 0.08 | 2.5e-04 | 4.2 | -5.3 | 8.6e-08 | -0.73 | 0.04 | 0.89 | TRUE |