[Hub]/) : Traits : Average weekly red wine intake : ← →

chr11:56,666,189-58,284,951

Best TWAS P=3.16e-10 · Best GWAS P=2.3e-09 conditioned to 1

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Esophagus Mucosa MED19 0.14 0.07 lasso 4 0.11 5.9e-08 -4.3 5.9 2.9e-09 -0.43 0.07 0.93 FALSE
2 GTEx Heart Atrial Appendage MED19 0.11 0.14 lasso 1 0.14 6.0e-07 -5.3 5.3 9.4e-08 -0.20 0.06 0.93 FALSE
3 GTEx Heart Left Ventricle CTNND1 0.07 0.04 lasso 5 0.00 1.8e-01 -5.7 5.9 3.4e-09 -0.99 0.01 0.91 TRUE
4 GTEx Pancreas MED19 0.10 0.08 lasso 3 0.02 5.0e-02 -5.2 5.2 1.8e-07 -0.21 0.06 0.61 FALSE
5 GTEx Skin Sun Exposed Lower leg ZDHHC5 0.05 0.03 lasso 8 0.02 6.2e-03 -5.4 -6.3 3.2e-10 0.28 0.04 0.95 TRUE
6 GTEx Skin Sun Exposed Lower leg MED19 0.15 0.11 lasso 7 0.09 1.3e-07 -5.4 5.6 1.9e-08 -0.28 0.05 0.95 FALSE
7 NTR Blood SERPING1 0.01 0.00 blup 399 0.00 2.9e-02 5.2 -5.8 7.3e-09 0.37 0.04 0.89 FALSE
8 ROSMAP Brain Pre-frontal Cortex ZDHHC5 0.05 0.02 blup 401 0.03 2.0e-04 -5.4 5.6 2.4e-08 -0.40 0.03 0.91 FALSE
9 ROSMAP Brain Pre-frontal Cortex AP000662.4 0.05 0.01 enet 17 0.02 3.8e-04 -4.4 5.9 4.1e-09 -0.50 0.17 0.80 FALSE
10 The Cancer Genome Atlas Colon Adenocarcinoma TMX2 0.07 0.06 lasso 1 0.05 5.0e-04 -5.4 -5.4 5.7e-08 0.22 0.00 0.91 FALSE
11 The Cancer Genome Atlas Esophageal Carcinoma MED19 0.10 0.06 lasso 4 0.02 5.4e-02 -5.4 5.4 5.7e-08 -0.22 0.00 0.83 FALSE
12 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma YPEL4 0.04 0.05 blup 33 0.04 2.6e-05 4.7 -5.3 1.3e-07 0.23 0.08 0.90 FALSE
13 The Cancer Genome Atlas Lung Squamous Cell Carcinoma MED19 0.03 0.02 lasso 1 0.01 1.8e-02 -5.3 5.3 9.4e-08 -0.20 0.00 0.83 FALSE
14 The Cancer Genome Atlas Prostate Adenocarcinoma TMX2 0.03 0.02 blup 29 0.02 3.7e-03 4.5 -5.4 6.0e-08 0.25 0.04 0.72 FALSE