[Hub]/) : Traits : Average weekly red wine intake :

chr7:140,705,484-142,344,964

Best TWAS P=2.09e-11 · Best GWAS P=1.15e-14 conditioned to 6.82e-05

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex CLEC5A 0.06 0.03 enet 15 0.04 1.1e-05 -5.1 5.5 4.5e-08 -0.60 0.78 0.21 FALSE
2 CommonMind Brain Pre-frontal Cortex TAS2R5 0.10 0.12 enet 17 0.14 6.8e-17 -4.8 5.2 1.9e-07 -0.54 1.00 0.00 FALSE
3 GTEx Adipose Visceral Omentum TAS2R4 0.09 0.07 lasso 1 0.07 2.1e-04 5.1 -5.1 3.0e-07 0.46 0.46 0.18 FALSE
4 GTEx Brain Cortex WEE2-AS1 0.36 0.36 enet 37 0.26 8.2e-08 -4.8 -5.1 2.7e-07 0.49 1.00 0.00 FALSE
5 GTEx Colon Sigmoid WEE2-AS1 0.26 0.14 enet 16 0.16 2.3e-06 -4.6 -5.8 5.8e-09 0.63 0.65 0.34 FALSE
6 GTEx Esophagus Gastroesophageal Junction TAS2R4 0.21 0.05 enet 26 0.03 2.4e-02 -4.6 -5.6 1.9e-08 0.53 0.09 0.80 FALSE
7 GTEx Spleen TAS2R6 0.40 0.12 enet 35 0.10 2.0e-03 -4.6 5.3 1.1e-07 -0.54 0.35 0.40 FALSE
8 GTEx Thyroid TAS2R6 0.08 0.06 lasso 2 0.05 1.5e-04 -5.0 5.4 8.4e-08 -0.48 0.87 0.08 FALSE
9 The Cancer Genome Atlas Brain Lower Grade Glioma MGAM 0.02 0.02 blup 5 0.02 5.8e-03 -7.5 6.7 2.1e-11 -0.78 0.00 0.83 TRUE
10 The Cancer Genome Atlas Brain Lower Grade Glioma TAS2R5 0.04 0.01 enet 8 0.02 4.7e-03 -4.8 5.2 1.6e-07 -0.51 0.02 0.80 FALSE
11 The Cancer Genome Atlas Stomach Adenocarcinoma TAS2R5 0.06 0.05 blup 41 0.05 1.4e-04 -4.6 5.1 2.9e-07 -0.53 0.02 0.91 FALSE
12 The Cancer Genome Atlas Thyroid Carcinoma PRSS37 0.06 0.06 enet 7 0.05 1.0e-05 -5.1 5.2 2.4e-07 -0.49 0.01 0.99 FALSE