Best TWAS P=2.27e-08 · Best GWAS P=1.07e-07 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Heart Left Ventricle | CTNND1 | 0.07 | 0.04 | lasso | 5 | 0.00 | 1.8e-01 | -5.3 | 5.3 | 1.3e-07 | -0.99 | 0.02 | 0.86 | TRUE |
| 2 | GTEx | Skin Sun Exposed Lower leg | ZDHHC5 | 0.05 | 0.03 | lasso | 8 | 0.02 | 6.2e-03 | -4.8 | -5.6 | 2.3e-08 | 0.28 | 0.13 | 0.82 | TRUE |
| 3 | YFS | Blood | SERPING1 | 0.04 | 0.04 | lasso | 6 | 0.04 | 1.2e-12 | -5.2 | -5.1 | 2.8e-07 | 0.21 | 0.01 | 0.99 | FALSE |