Best TWAS P=4.8e-08 · Best GWAS P=3.06e-07 conditioned to 0.901
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Colon Transverse | RP4-758J18.13 | 0.13 | 0.05 | enet | 16 | 0.04 | 6.1e-03 | 4.0 | -5.3 | 1.0e-07 | -0.67 | 0.02 | 0.68 | FALSE |
| 2 | GTEx | Skin Not Sun Exposed Suprapubic | ANKRD65 | 0.35 | 0.23 | lasso | 5 | 0.25 | 8.5e-14 | 5.0 | -5.1 | 2.7e-07 | -0.81 | 0.01 | 0.99 | FALSE |
| 3 | GTEx | Testis | PUSL1 | 0.19 | 0.02 | lasso | 6 | 0.05 | 3.8e-03 | 4.1 | -5.2 | 2.3e-07 | -0.38 | 0.06 | 0.14 | TRUE |
| 4 | ROSMAP | Brain Pre-frontal Cortex | CPSF3L | 0.13 | 0.12 | bslmm | 247 | 0.12 | 2.2e-15 | 5.1 | 5.3 | 1.2e-07 | 0.98 | 0.01 | 0.99 | FALSE |
| 5 | The Cancer Genome Atlas | Brain Lower Grade Glioma | LOC441869 | 0.08 | 0.10 | blup | 16 | 0.11 | 1.7e-12 | 5.0 | -5.5 | 4.8e-08 | -0.89 | 0.00 | 0.99 | TRUE |
| 6 | The Cancer Genome Atlas | Prostate Adenocarcinoma | LOC441869 | 0.06 | 0.11 | lasso | 4 | 0.11 | 2.5e-11 | 5.1 | -5.1 | 2.7e-07 | -0.89 | 0.00 | 1.00 | FALSE |
| 7 | The Cancer Genome Atlas | Rectum Adenocarcinoma | LOC441869 | 0.37 | 0.23 | lasso | 4 | 0.19 | 2.6e-05 | 5.0 | -5.2 | 1.6e-07 | -0.90 | 0.00 | 0.97 | FALSE |
| 8 | The Cancer Genome Atlas | Thyroid Carcinoma | LOC441869 | 0.05 | 0.07 | lasso | 3 | 0.06 | 6.6e-07 | 5.0 | -5.1 | 2.7e-07 | -0.91 | 0.00 | 0.99 | FALSE |