TWAS hub - LOC441869

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	TCGA	Breast Invasive Carcinoma	0.0314	0.0172	5.2e-06	0.036	0.031	0.031	NA	0.034	4.9e-08	4.0e-07	3.9e-07	NA	1.4e-07
2	TCGA	Colon Adenocarcinoma	0.2220	0.0730	1.3e-11	0.190	0.220	0.190	NA	0.200	3.3e-11	7.3e-13	3.4e-11	NA	9.4e-12
3	TCGA	Glioblastoma Multiforme	0.1020	0.0550	1.8e-03	0.099	0.058	0.055	NA	0.065	6.3e-04	7.5e-03	9.3e-03	NA	5.1e-03
4	TCGA	Kidney Renal Clear Cell Carcinoma	0.0320	0.0179	6.5e-05	0.024	0.024	0.019	NA	0.022	9.2e-04	8.5e-04	2.6e-03	NA	1.5e-03
5	TCGA	Kidney Renal Papillary Cell Carcinoma	0.0460	0.0340	5.9e-03	0.024	0.035	0.025	NA	0.032	1.5e-02	4.1e-03	1.3e-02	NA	5.9e-03
6	TCGA	Brain Lower Grade Glioma	0.0818	0.0350	2.1e-11	0.099	0.110	0.096	NA	0.098	2.3e-11	1.7e-12	4.9e-11	NA	3.2e-11
7	TCGA	Lung Squamous Cell Carcinoma	0.0599	0.0304	8.2e-06	0.049	0.052	0.041	NA	0.047	2.7e-06	1.4e-06	1.8e-05	NA	4.6e-06
8	TCGA	Pancreatic Adenocarcinoma	0.1150	0.0620	1.2e-04	0.086	0.078	0.071	NA	0.100	1.8e-04	3.6e-04	6.7e-04	NA	5.6e-05
9	TCGA	Pheochromocytoma and Paraganglioma	0.1030	0.0610	1.9e-03	0.035	0.025	0.021	NA	0.035	1.5e-02	3.6e-02	4.8e-02	NA	1.5e-02
10	TCGA	Prostate Adenocarcinoma	0.0626	0.0262	1.5e-10	0.110	0.103	0.107	NA	0.108	1.3e-11	7.1e-11	2.8e-11	NA	2.5e-11
11	TCGA	Rectum Adenocarcinoma	0.3710	0.1450	1.9e-05	0.228	0.178	0.192	NA	0.194	4.6e-06	5.6e-05	2.9e-05	NA	2.6e-05
12	TCGA	Stomach Adenocarcinoma	0.0390	0.0220	2.8e-04	0.069	0.059	0.059	NA	0.059	1.0e-05	4.4e-05	4.7e-05	NA	4.3e-05
13	TCGA	Thyroid Carcinoma	0.0460	0.0240	6.8e-06	0.067	0.059	0.057	NA	0.065	4.2e-07	2.1e-06	3.0e-06	NA	6.6e-07

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13
Breastfed as a baby	18.3	22.8	29.8	-4.4	-3.8	-4.3	-5.0	-4.0	-5.5	-4.2	-4.9	-5.1	-5.1	-5.2	-5.0	-5.1
Systolic blood pressure, automated reading	10.1	29.2	38.1	5.4	4.0	5.3	5.6	5.2	6.0	5.3	5.3	6.2	5.3	5.6	5.3	5.5
Illnesses of siblings	9.7	13.6	20.2	-3.4	-3.5	-3.3	-4.0	-2.5	-4.5	-2.6	-3.5	-4.3	-4.1	-4.0	-3.8	-4.0
Birth weight of first child	8.5	15.4	21.3	-3.7	-3.5	-3.6	-3.8	-2.3	-4.4	-3.0	-3.5	-4.1	-4.6	-4.6	-4.4	-4.6
High blood pressure (siblings)	7.5	10.9	14.7	3.2	2.8	3.1	3.4	2.6	3.8	2.7	3.4	3.8	3.4	3.5	3.3	3.4
Peak expiratory flow (PEF)	7.0	16.3	24.9	-4.5	-2.4	-4.2	-3.0	-4.1	-3.9	-5.0	-4.3	-4.3	-3.7	-4.4	-4.1	-3.8
Medication: Lisinopril	7.0	9.1	12.0	3.1	3.3	3.1	3.2	1.7	3.2	1.6	2.8	3.0	3.4	3.5	3.3	3.3
Irritable Bowel Disease (IBD)	6.9	16.5	23.3	-4.2	-2.6	-4.0	-3.5	-4.5	-3.8	-4.8	-4.5	-4.7	-3.7	-4.0	-4.1	-3.9
Ulcerative Colitis (UC)	6.9	12.9	24.0	-4.1	-1.7	-3.8	-2.9	-4.3	-3.1	-4.9	-4.0	-3.6	-3.1	-3.2	-3.4	-3.3
Systolic Blood Pressure	6.6	32.9	44.0	5.6	4.7	5.5	5.4	5.1	5.8	5.7	5.7	5.1	6.6	6.1	6.4	6.5
Had other major operations	6.2	7.5	9.1	-2.7	-1.9	-2.6	-2.8	-2.8	-2.9	-2.8	-2.6	-3.0	-2.9	-2.9	-2.8	-2.8
High blood pressure (mother)	5.7	7.9	11.2	2.3	2.9	2.3	3.2	2.3	3.3	1.7	2.9	3.4	3.0	3.0	2.9	3.0
Father’s age at death	5.7	7.7	11.4	2.6	2.2	2.5	2.9	3.1	2.7	2.5	3.4	2.8	2.6	3.0	2.9	2.7
Hypothyroidism/myxoedema (self-reported)	5.2	10.2	14.8	3.2	1.7	2.9	2.7	2.9	3.3	3.9	3.5	3.2	3.3	3.6	3.4	3.4
Crohns Disease (2017)	5.0	10.9	18.7	-3.0	-2.6	-2.9	-3.1	-3.5	-3.4	-3.3	-3.5	-4.3	-3.1	-3.4	-3.4	-3.1
Medication: Levothyroxine sodium	4.6	7.9	13.0	3.2	1.4	2.9	2.0	2.4	2.7	3.6	3.0	2.6	2.9	3.2	3.0	2.9
Mother’s age at death	4.5	5.6	9.2	2.2	1.9	2.2	2.7	2.5	2.8	2.1	2.2	3.0	2.0	2.2	2.2	2.3
Mouth/teeth dental problems: Dentures	4.2	7.1	9.2	2.6	2.2	2.6	3.0	2.5	3.0	2.3	2.6	3.0	2.7	2.7	2.6	2.7
Illnesses of father: High blood pressure	4.2	5.2	8.2	2.5	2.9	2.5	2.4	0.8	2.1	0.6	2.2	2.0	2.7	2.6	2.5	2.5
Illnesses of mother	4.1	5.0	8.5	-1.4	-2.9	-1.6	-2.6	-1.0	-2.7	-0.4	-1.9	-2.5	-2.7	-2.6	-2.5	-2.6
Number of operations (self-reported)	3.8	5.6	8.1	-2.4	-2.1	-2.3	-2.2	-2.0	-2.2	-1.9	-2.4	-2.3	-2.7	-2.8	-2.7	-2.5
Loneliness, isolation	3.7	5.1	8.7	-1.8	-2.6	-1.8	-2.3	-1.1	-2.8	-1.0	-1.8	-3.0	-2.5	-2.6	-2.5	-2.5
Hypothyroidism (self reported)	3.6	8.2	16.3	3.1	1.4	2.8	1.8	3.1	2.2	4.0	3.4	2.4	2.9	3.0	3.1	2.9
Illnesses of father: None of the above (group 1)	3.5	4.4	6.1	-2.2	-1.8	-2.1	-2.1	-1.9	-2.0	-1.8	-2.0	-2.0	-2.2	-2.5	-2.4	-2.3
Lung FVC	3.4	17.1	20.8	-4.6	-3.2	-4.5	-4.3	-3.5	-4.1	-4.0	-4.1	-4.0	-4.4	-4.2	-4.3	-4.4
Forced expiratory volume in 1-second (FEV1)	3.4	11.3	15.4	-3.9	-2.6	-3.8	-3.1	-3.4	-3.4	-3.4	-3.5	-3.8	-3.0	-3.4	-3.2	-3.1
Tinnitus: Yes, but not now, but have in the past	3.2	3.4	5.2	2.3	1.1	2.3	1.9	1.8	1.8	2.1	1.9	1.6	1.6	1.7	1.7	1.8
Medication: Ibuprofen (e.g. Nurofen)	3.2	4.1	7.2	-2.6	-2.5	-2.7	-2.2	-1.0	-1.9	-0.7	-1.9	-2.0	-2.0	-1.9	-1.9	-1.9
Medication: Ibuprofen	3.1	3.7	7.8	-2.7	-2.6	-2.8	-2.0	-0.9	-1.8	-0.5	-1.7	-2.1	-1.7	-1.7	-1.6	-1.6
Alcohol drinker status: Previous	3.1	3.6	5.4	-2.1	-2.1	-2.1	-1.9	-1.5	-2.0	-1.2	-2.0	-2.3	-1.8	-1.8	-1.8	-1.7
Medication for cholesterol, blood pressure or diabetes	3.0	4.9	8.4	-1.7	-2.3	-1.8	-2.3	-1.1	-2.9	-1.3	-2.0	-2.5	-2.6	-2.5	-2.4	-2.6
Qualifications: None of the above	2.9	6.2	8.7	2.2	1.8	2.1	2.4	2.4	2.8	2.5	2.4	3.0	2.6	2.8	2.6	2.6
Qualifications: CSEs or equivalent	2.8	3.7	6.4	-2.1	-2.5	-2.1	-2.2	-1.0	-2.1	-0.4	-1.6	-2.3	-1.9	-1.9	-1.9	-1.9
Forced vital capacity (FVC)	2.8	10.9	14.1	-3.5	-2.2	-3.4	-3.0	-3.6	-3.4	-3.6	-3.5	-3.8	-2.9	-3.4	-3.2	-3.1
Loud music exposure frequency	2.8	3.0	4.4	-1.2	-2.1	-1.2	-1.9	-1.2	-2.0	-0.5	-1.4	-2.1	-2.0	-2.1	-2.0	-1.9
Back pain experienced in last month	2.8	4.1	6.5	-1.3	-2.2	-1.2	-2.0	-1.1	-2.4	-1.0	-2.1	-2.1	-2.5	-2.5	-2.4	-2.3
Age when periods started (menarche)	2.6	6.2	7.9	-2.6	-2.7	-2.6	-2.8	-1.8	-2.6	-1.3	-2.6	-2.6	-2.5	-2.6	-2.6	-2.6
Medication: Cholesterol lowering	2.6	4.1	7.1	1.5	1.9	1.6	2.2	1.1	2.7	1.3	1.8	2.3	2.3	2.3	2.2	2.4
Medication: Aspirin	2.6	3.4	5.2	2.2	2.3	2.3	1.9	0.0	2.0	0.4	1.2	1.6	2.1	2.1	1.9	2.2
Osteoporosis (self-reported)	2.6	3.2	5.2	-0.7	-2.3	-0.8	-2.2	-0.7	-2.2	-0.1	-1.4	-1.8	-2.3	-2.3	-2.2	-2.3
Heart disease (siblings)	2.5	3.1	4.1	1.3	1.0	1.2	1.8	1.8	2.0	1.9	1.6	1.9	2.0	2.0	1.9	2.0
Vitamin and mineral supplements	2.4	3.2	4.5	1.1	1.3	1.0	1.9	2.1	1.9	1.6	2.0	1.9	1.9	2.1	2.0	1.9
Reaction Time	2.3	4.3	6.2	-1.7	-1.6	-1.7	-2.1	-2.2	-2.1	-2.1	-2.0	-1.6	-2.5	-2.2	-2.4	-2.4
Forced expiratory volume in 1-second (FEV1), Best measure	2.3	7.4	10.9	-3.3	-2.4	-3.2	-2.4	-2.8	-2.6	-2.5	-2.8	-3.1	-2.4	-2.7	-2.6	-2.3
Leg pain on walking	2.3	2.9	3.8	1.9	1.3	1.9	1.9	1.1	1.8	1.4	1.6	1.4	1.9	1.8	1.7	2.0
Mineral and other dietary supplements	2.3	3.0	6.8	1.4	0.3	1.3	1.8	2.4	2.0	2.6	1.8	2.0	1.4	1.5	1.4	1.6
Supplements: Calcium	2.3	2.6	5.6	-0.9	-0.2	-0.8	-1.8	-2.2	-1.8	-2.4	-1.6	-1.6	-1.5	-1.6	-1.5	-1.7
Ever had hysterectomy (womb removed)	2.2	2.4	4.0	1.8	1.6	1.9	2.0	0.9	1.6	0.7	1.1	1.6	1.6	1.6	1.6	1.7
Mouth/teeth dental problems	2.1	3.2	4.7	-1.7	-1.9	-1.7	-2.2	-1.3	-2.0	-0.9	-1.8	-2.0	-1.8	-1.8	-1.7	-1.8
Comparative height size at age 10	2.0	11.1	14.4	3.6	3.7	3.7	3.8	1.6	3.7	1.5	2.7	3.3	3.7	3.6	3.5	3.7
Supplements: Vitamin C	2.0	2.4	4.4	-1.4	-1.3	-1.3	-1.2	-0.9	-1.5	-1.3	-1.6	-1.3	-2.0	-2.1	-2.0	-1.9
Diabetes (father)	1.9	2.3	3.8	1.7	1.8	1.7	1.5	1.1	1.7	0.7	1.4	1.9	1.4	1.6	1.5	1.5
Number of live births	1.9	2.7	4.1	2.0	1.7	2.0	2.0	0.7	1.8	0.8	1.7	1.6	1.6	1.5	1.4	1.7
Wears glasses or contact lenses	1.9	2.2	3.7	0.8	1.8	0.9	1.6	0.4	1.9	0.3	1.4	1.5	1.8	1.8	1.7	1.8
Supplements: Fish oil (including cod liver oil)	1.9	2.5	4.7	-1.0	-0.7	-1.0	-1.9	-2.2	-1.9	-1.8	-1.8	-1.8	-1.4	-1.4	-1.4	-1.5
Hayfever, allergic rhinitis or eczema	1.8	4.0	6.5	-2.1	-1.8	-2.0	-1.6	-1.9	-2.1	-1.8	-2.1	-2.5	-1.9	-2.2	-2.0	-1.9
Number of full brothers	1.8	2.3	3.9	-2.0	-1.5	-1.9	-1.5	-1.2	-1.4	-1.1	-1.7	-1.6	-1.4	-1.5	-1.4	-1.4
Medication: Aspirin	1.7	2.2	3.6	1.6	1.9	1.7	1.6	0.1	1.7	0.3	1.0	1.3	1.7	1.7	1.6	1.8
Supplements: Zinc	1.5	1.6	5.0	-1.3	-0.2	-1.2	-1.2	-2.2	-1.0	-1.9	-1.2	-1.5	-0.9	-0.9	-0.9	-0.8
Supplements: Glucosamine	1.5	1.9	4.2	-1.3	-0.3	-1.1	-1.2	-1.7	-1.6	-2.0	-1.3	-1.9	-1.0	-1.2	-1.2	-1.3
Hair/balding pattern: Pattern 2	1.5	1.9	3.8	0.4	0.6	0.3	1.5	1.3	1.9	1.5	1.4	1.3	1.6	1.6	1.5	1.6
Depression (self-reported)	1.5	1.8	2.9	0.6	0.6	0.6	1.4	1.2	1.7	1.6	1.6	1.2	1.5	1.6	1.5	1.6
Exposure to tobacco smoke outside home	1.5	2.0	5.5	-2.0	-2.3	-2.0	-1.1	0.2	-1.1	0.4	-0.9	-1.5	-1.2	-1.4	-1.3	-1.2
Medication for pain relief, constipation, heartburn	1.5	2.6	4.9	-1.1	-0.7	-1.1	-1.9	-1.1	-2.2	-1.8	-1.4	-1.6	-1.7	-1.8	-1.7	-2.1
Unable to work because of sickness or disability	1.5	2.0	5.4	-1.4	-0.9	-1.4	-1.4	-2.3	-1.4	-1.6	-1.5	-1.9	-0.8	-1.0	-1.0	-0.8
Ovarian Cancer	1.4	1.8	2.9	1.1	1.6	1.2	1.5	0.7	1.6	0.5	1.7	0.4	1.7	1.5	1.4	1.6
Hayfever/allergic rhinitis (self-reported)	1.3	1.7	3.0	-1.6	-0.7	-1.5	-0.9	-1.4	-1.1	-1.7	-1.2	-1.3	-1.2	-1.4	-1.3	-1.2
Serious illness, injury or assault of a close relative in last 2 years	1.3	1.5	4.3	1.1	2.1	1.2	1.3	-0.4	1.3	-0.7	0.5	1.2	1.5	1.4	1.3	1.4
Medication: Paracetamol	1.3	2.1	3.7	1.2	0.6	1.2	1.8	1.0	1.9	1.6	1.4	1.2	1.5	1.4	1.4	1.8
Forced vital capacity (FVC), Best measure	1.3	4.9	7.0	-2.5	-1.6	-2.4	-1.8	-2.6	-2.0	-2.4	-2.4	-2.6	-1.8	-2.2	-2.1	-1.8
Medication: Blood pressure	1.3	2.2	3.4	1.2	1.8	1.2	1.4	0.5	1.8	0.5	1.5	1.6	1.8	1.8	1.7	1.7
Mouth/teeth dental problems: Mouth ulcers	1.3	2.1	3.1	-1.7	-1.3	-1.6	-1.3	-0.9	-1.6	-1.2	-1.1	-1.7	-1.5	-1.6	-1.5	-1.6
Medication: Paracetamol	1.3	2.0	3.6	1.1	0.8	1.1	1.7	0.8	1.9	1.4	1.6	1.2	1.6	1.5	1.4	1.8
Age started oral contraceptive pill	1.3	1.6	2.6	1.6	1.1	1.6	1.3	1.0	1.3	1.1	1.1	1.4	1.1	1.3	1.2	1.3
Verbal and Numeric Reasoning (VNR)	1.2	2.8	5.4	1.2	1.7	1.3	2.3	1.2	1.9	0.8	1.6	2.2	1.6	1.7	1.7	1.8
Heel bone mineral density (BMD) T-score, automated (left)	1.2	2.7	5.9	0.9	1.8	1.1	2.4	0.2	2.4	0.2	1.2	1.8	2.0	1.6	1.5	2.0
Birth weight	1.2	2.5	3.3	-1.6	-1.1	-1.5	-1.6	-1.3	-1.7	-1.5	-1.8	-1.4	-1.7	-1.7	-1.7	-1.7
Allergy or Eczema	1.1	2.8	3.5	-1.9	-1.4	-1.8	-1.2	-1.9	-1.5	-1.7	-1.7	-1.5	-1.7	-1.9	-1.9	-1.7
Angina	1.1	1.5	3.0	-1.7	-1.0	-1.7	-1.4	-1.3	-1.1	-1.0	-1.1	-1.5	-0.8	-0.8	-0.8	-0.9
Relative age voice broke	1.1	1.7	4.3	-2.0	-0.2	-1.9	-0.9	-1.0	-1.0	-2.1	-1.3	-0.6	-1.1	-1.3	-1.1	-1.2
High blood pressure	1.1	3.0	6.1	1.9	2.5	2.0	1.6	0.3	1.8	0.2	1.6	1.9	1.8	1.9	1.8	1.8
Financial difficulties in last 2 years	1.1	1.5	3.9	-0.4	-0.4	-0.4	-1.2	-2.0	-1.6	-1.5	-1.2	-1.9	-0.8	-0.9	-0.9	-0.9
Fluid intelligence score	1.1	2.3	3.6	1.1	0.9	1.1	1.9	1.6	1.6	1.4	1.6	1.2	1.6	1.7	1.7	1.7
Emphysema/chronic bronchitis	1.1	1.2	2.8	-0.9	-0.5	-0.8	-0.9	-1.7	-1.0	-1.4	-1.2	-1.4	-0.9	-1.1	-1.1	-0.9
Alcohol drinker status: Never	1.1	1.3	1.9	-1.3	-0.7	-1.3	-1.2	-1.1	-1.2	-1.1	-1.4	-1.3	-1.0	-1.0	-0.9	-1.0
Ever had prostate specific antigen (PSA) test	1.1	1.3	1.6	-1.2	-0.7	-1.1	-1.2	-1.2	-1.0	-1.2	-1.3	-0.9	-1.2	-1.3	-1.2	-1.2
Fractured/broken bones in last 5 years	1.1	1.4	3.6	0.3	-0.7	0.2	-1.5	-0.9	-1.9	-0.8	-1.1	-1.4	-1.3	-1.3	-1.3	-1.5
Blood Eosinophil Count	1.0	7.8	11.6	-3.4	-2.8	-3.3	-2.5	-2.4	-2.5	-2.2	-3.3	-2.4	-2.8	-2.9	-2.9	-2.7
Past tobacco smoking	1.0	1.9	3.6	0.9	0.4	0.8	1.3	1.8	1.7	1.9	1.2	1.9	1.1	1.2	1.2	1.3
Frequency of tiredness / lethargy in last 2 weeks	1.0	1.7	2.4	1.5	1.1	1.5	1.3	0.9	1.2	1.0	1.4	1.3	1.2	1.4	1.3	1.4
Angina (self-reported)	1.0	1.3	2.7	-1.6	-1.1	-1.6	-1.4	-1.2	-1.1	-0.8	-1.1	-1.5	-0.8	-0.8	-0.8	-0.8
Smoking status: Previous	1.0	1.5	3.1	-0.9	-0.3	-0.9	-1.3	-1.5	-1.5	-1.8	-1.2	-1.4	-1.0	-1.1	-1.1	-1.2
Financial situation satisfaction	1.0	1.2	3.2	1.1	1.8	1.2	1.1	-0.3	0.8	-0.4	1.0	0.6	1.4	1.3	1.2	1.2
Ever smoked	1.0	1.8	4.4	-0.9	-0.8	-0.8	-1.4	-1.6	-1.8	-1.4	-1.1	-2.1	-1.1	-1.3	-1.2	-1.3
Vascular/heart problems diagnosed by doctor	1.0	2.7	5.4	-1.6	-2.3	-1.7	-1.6	-0.2	-1.9	-0.2	-1.5	-1.8	-1.8	-1.8	-1.7	-1.7
Prostate Cancer	0.9	1.3	2.7	1.6	1.0	1.7	1.4	0.3	1.1	0.8	0.8	1.3	1.2	0.8	0.9	1.2
Medication for hormone replacement therapy	0.9	1.0	3.8	-1.9	-0.4	-1.9	-0.9	-1.0	-0.5	-1.1	-0.7	-0.9	-0.4	-0.5	-0.5	-0.6
Bilateral oophorectomy (both ovaries removed)	0.9	1.1	1.6	1.0	1.3	1.0	1.3	0.3	1.1	0.2	0.9	0.9	1.2	1.2	1.1	1.2
Medication: Simvastatin	0.9	1.4	2.0	1.0	0.8	1.0	1.4	1.2	1.3	1.1	1.2	1.2	1.2	1.2	1.2	1.3
Age at first live birth	0.9	1.5	2.5	1.5	1.3	1.6	1.4	0.9	1.3	0.7	1.3	1.5	1.0	1.1	1.0	1.1
Pack years of smoking	0.9	1.3	1.9	0.9	0.5	0.9	1.4	1.3	1.3	1.4	1.3	1.0	1.2	1.1	1.1	1.2
Eye problems/disorders: Diabetes related eye disease	0.8	0.9	1.1	-1.0	-0.9	-1.0	-1.1	-0.6	-1.1	-0.7	-1.1	-0.8	-1.1	-1.0	-1.0	-1.0
Stomach or abdominal pain in last month	0.8	0.9	2.6	0.3	-0.2	0.2	1.2	1.3	1.2	1.6	1.2	0.7	0.8	0.8	0.8	1.0
Length of working week for main job	0.8	0.9	3.0	1.4	-0.1	1.3	0.6	1.4	0.6	1.7	0.6	0.9	0.5	0.6	0.5	0.5
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.8	1.0	1.7	-0.8	-0.3	-0.8	-1.1	-1.0	-1.3	-1.3	-1.2	-1.1	-0.9	-0.9	-0.8	-1.0
Hypertension (Self-reported)	0.8	2.2	4.1	1.9	2.0	1.9	1.3	0.1	1.5	0.3	1.3	1.5	1.5	1.6	1.5	1.5
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.8	1.7	4.0	-2.0	-0.9	-2.0	-1.0	-0.9	-1.0	-1.4	-1.3	-0.8	-1.2	-1.3	-1.2	-1.2
Number of self-reported non-cancer illnesses	0.8	1.5	2.3	1.0	0.6	0.9	1.2	1.3	1.4	1.5	1.5	1.2	1.1	1.3	1.2	1.2
Neuroticism	0.7	1.6	3.8	1.6	0.2	1.5	1.2	1.4	0.9	1.9	1.6	0.9	1.1	1.1	1.1	1.2
Hearing difficulty/problems: Yes	0.7	1.0	2.5	-0.5	-0.3	-0.4	-1.0	-1.6	-1.2	-1.4	-0.8	-1.2	-0.8	-1.0	-1.0	-0.9
Chronic bronchitis/emphysema (father)	0.7	0.8	1.7	-1.1	-1.3	-1.2	-1.0	-0.1	-1.1	-0.0	-0.6	-1.1	-0.7	-0.7	-0.7	-0.8
Blood clot in the leg (DVT)	0.7	0.9	1.4	-0.6	-0.4	-0.5	-0.9	-1.1	-1.2	-1.1	-0.8	-1.2	-0.8	-1.0	-1.0	-1.0
Wheeze or whistling in the chest in last year	0.7	1.2	2.8	1.7	0.9	1.7	1.1	0.7	1.1	1.1	1.1	1.1	0.9	1.0	0.9	1.0
Age at last live birth	0.7	1.1	2.9	1.4	1.7	1.4	1.0	0.2	0.9	-0.2	1.0	1.1	0.9	0.9	0.9	0.8
Mood swings	0.7	1.2	4.0	0.5	-0.3	0.4	1.0	1.8	1.1	2.0	1.3	0.8	0.8	1.0	0.9	1.0
Multivitamins +/- minerals	0.6	0.8	2.9	-0.5	-0.3	-0.4	-0.8	-1.7	-0.8	-1.3	-1.0	-1.0	-0.7	-0.9	-0.8	-0.7
Sitting height	0.6	4.3	9.2	1.8	3.0	2.1	2.9	-0.4	2.4	-0.7	1.2	1.7	2.4	2.0	1.9	2.4
Lung cancer (father)	0.6	0.7	1.4	0.5	1.1	0.5	0.7	0.6	1.0	0.3	0.7	1.2	0.9	1.0	0.9	0.8
Seen a psychiatrist for nerves, anxiety, tension or depression	0.6	0.8	3.1	-0.7	-1.8	-0.8	-0.9	-0.2	-0.7	0.8	-0.6	-1.1	-0.8	-0.8	-0.8	-0.6
Mean time to correctly identify matches	0.6	1.2	2.1	-0.2	-1.2	-0.3	-1.2	-0.8	-1.3	-0.4	-0.9	-1.1	-1.4	-1.4	-1.4	-1.3
Diabetes diagnosed by doctor	0.6	1.0	1.7	0.6	1.3	0.6	1.1	0.5	1.2	0.2	0.7	1.2	1.2	1.3	1.2	1.2
Medication: Atorvastatin	0.6	0.8	1.3	-0.9	-1.0	-0.9	-1.1	-1.1	-0.7	-0.4	-1.1	-1.0	-0.7	-0.8	-0.8	-0.7
Alzheimer’s Disease (in father)	0.5	0.6	1.7	-0.4	-0.1	-0.3	0.1	-1.3	0.0	-1.1	-0.8	1.1	-0.7	-0.8	-0.9	-0.6
Waist Hip Ratio (WHR)	0.5	2.2	3.1	1.5	1.2	1.5	1.5	1.5	1.1	1.4	1.7	0.9	1.6	1.6	1.8	1.7
Smoking Status	0.5	1.1	2.4	-1.5	-0.6	-1.4	-0.2	-1.4	-0.6	-1.5	-0.9	-0.7	-0.8	-1.0	-1.0	-0.8
Pack years adult smoking proportion	0.5	0.8	1.4	0.7	0.3	0.7	1.1	1.0	1.0	1.2	1.1	0.7	1.0	0.9	0.9	1.0
Hand grip strength (right)	0.5	1.3	2.3	1.4	1.5	1.5	1.3	0.7	1.1	0.3	0.8	1.3	1.1	1.1	1.1	1.0
Maternal smoking around birth	0.5	0.7	1.2	-0.4	-0.6	-0.4	-0.9	-0.7	-1.1	-0.7	-0.5	-1.0	-0.9	-1.0	-1.0	-1.0
Medication: Atenolol	0.5	0.7	1.8	0.8	1.4	0.8	0.6	0.1	0.8	-0.2	0.4	1.1	0.8	1.0	0.9	0.8
Heel bone mineral density (BMD) T-score, automated (right)	0.5	1.0	2.5	0.0	1.4	0.2	1.6	-0.6	1.6	-0.7	0.4	1.0	1.3	0.8	0.8	1.2
Allergy	0.5	1.1	2.4	1.0	0.4	0.8	0.5	1.3	1.0	1.5	1.2	1.4	0.8	1.1	1.0	0.8
Alcohol intake versus 10 years previously	0.5	0.8	2.0	1.2	0.1	1.1	0.9	1.0	0.8	1.4	1.0	0.7	0.7	0.7	0.7	0.8
Qualifications: O levels/GCSEs or equivalent	0.5	0.8	1.8	0.0	-0.1	0.2	-0.6	-1.3	-1.0	-1.4	-1.0	-1.1	-0.9	-1.0	-1.0	-0.9
Mouth/teeth dental problems: Bleeding gums	0.5	0.7	1.9	0.6	1.4	0.6	0.9	0.5	0.8	-0.2	0.7	1.0	0.8	0.9	0.9	0.7
Leg fat percentage (right)	0.5	1.7	3.9	1.5	0.0	1.5	1.6	1.7	1.5	2.0	1.1	1.5	0.6	0.6	0.6	1.0
Medication: Omeprazole	0.5	0.6	2.0	-0.1	-1.4	-0.2	-0.9	-0.7	-0.7	0.5	-0.7	-1.0	-0.7	-0.7	-0.8	-0.5
Heart disease (mother)	0.5	0.6	1.0	1.0	0.7	1.0	0.3	-0.0	0.9	0.7	0.6	0.6	0.9	1.0	0.9	0.9
Number of full sisters	0.5	0.6	1.0	0.5	0.6	0.4	0.7	1.0	0.8	0.7	0.8	0.8	0.8	0.9	0.8	0.7
Illnesses of father: Heart disease	0.5	0.7	1.4	0.4	0.6	0.3	0.7	1.2	0.8	0.8	0.6	1.0	0.8	1.1	1.1	0.9
Friendships satisfaction	0.5	0.6	1.3	0.9	0.5	0.9	0.8	0.7	1.0	0.8	0.5	1.2	0.6	0.6	0.6	0.7
Cholesterol lowering medication	0.5	0.7	1.1	-0.6	-0.6	-0.5	-0.6	-1.1	-0.8	-0.9	-1.0	-1.0	-0.8	-0.9	-0.9	-0.7
Deep venous thrombosis (DVT) (self-reported)	0.5	0.6	1.2	-0.6	-0.2	-0.5	-0.7	-0.9	-1.0	-1.1	-0.7	-0.9	-0.7	-0.8	-0.8	-0.8
Intelligence (Savage-Jansen 2018)	0.4	1.2	3.0	1.0	1.7	1.1	1.2	0.7	1.0	-0.2	1.0	1.2	1.0	1.1	1.1	1.0
Neuroticism (Nagel 2018)	0.4	0.9	2.6	1.2	0.3	1.1	0.4	1.6	0.5	1.4	1.3	0.2	0.5	0.8	0.7	0.6
Breast Cancer	0.4	1.0	1.7	-1.0	-1.2	-1.0	-1.1	-0.6	-1.3	-0.1	-0.9	-0.7	-1.0	-1.3	-1.0	-1.1
Neuroticism (2016)	0.4	0.6	1.6	0.6	0.0	0.5	0.4	0.9	0.4	1.1	0.5	0.5	0.0	1.2	1.3	1.1
Blood Platelet Count	0.4	4.8	8.4	-2.1	-2.9	-2.2	-2.5	-0.8	-2.7	-0.2	-1.9	-1.9	-2.4	-2.5	-2.3	-2.5
Heel T-Score	0.4	3.5	8.5	1.5	2.7	1.9	2.9	-1.1	2.4	-1.4	0.6	1.1	2.0	1.6	1.4	2.2
Respiratory disease	0.4	1.0	4.3	-0.5	0.4	-0.3	-0.2	-1.7	-0.7	-2.1	-1.2	-0.1	-0.8	-0.8	-0.9	-0.9
Chronotype (morning person)	0.4	1.0	4.3	1.1	2.1	1.2	0.9	-0.0	0.8	-1.2	0.5	0.0	0.8	1.1	0.9	0.8
Hair Pigment	0.4	11.2	16.5	-4.1	-2.2	-3.9	-2.8	-3.0	-2.9	-4.0	-3.6	-3.2	-3.3	-3.2	-3.3	-3.3
Severe depression (siblings)	0.4	0.5	1.0	-0.1	-0.0	-0.2	0.6	0.7	0.9	1.0	0.5	0.7	0.8	0.8	0.8	0.9
Heart attack	0.4	0.4	1.0	-1.0	-0.4	-1.0	-0.7	-1.0	-0.5	-0.7	-0.6	-0.9	-0.2	-0.3	-0.3	-0.3
Time employed in main current job	0.4	0.5	1.8	-1.3	-0.6	-1.3	-0.8	-0.5	-0.4	-0.4	-0.7	-0.6	-0.3	-0.2	-0.3	-0.3
Pulse rate	0.4	0.6	1.4	0.1	-1.1	0.2	-0.6	-0.6	-0.7	0.1	-1.0	-0.7	-0.9	-1.2	-1.1	-0.8
Prospective memory result	0.4	0.4	1.6	0.6	1.2	0.6	0.6	-0.8	0.6	-0.9	0.5	0.5	0.6	0.3	0.2	0.4
Seen doctor (GP) for nerves, anxiety, tension or depression	0.4	0.6	2.0	-0.9	-1.0	-0.9	-0.7	-0.6	-1.0	-0.3	-0.3	-1.4	-0.7	-0.7	-0.7	-0.7
Worry too long after embarrassment	0.4	0.7	1.4	1.2	0.2	1.1	0.8	0.9	0.6	1.1	1.2	0.6	0.5	0.5	0.5	0.6
Reason for reducing amount of alcohol drunk: Health precaution	0.4	0.5	1.1	0.1	0.8	0.2	0.7	0.0	1.0	0.2	0.7	0.6	1.0	0.9	0.9	1.0
Shortness of breath walking on level ground	0.4	0.5	2.7	-0.0	0.2	0.1	-0.3	-1.6	-0.4	-1.3	-1.1	-0.6	-0.3	-0.4	-0.4	-0.1
Medication: Seretide 50 evohaler	0.4	0.4	2.5	-0.7	1.1	-0.5	0.7	-0.4	0.2	-1.6	0.3	-0.0	0.3	0.1	0.2	0.1
Leg fat mass (right)	0.4	1.4	2.9	1.4	0.2	1.4	1.4	1.4	1.5	1.7	1.0	1.3	0.7	0.7	0.7	1.0
Family relationship satisfaction	0.4	0.5	2.0	0.8	1.4	1.0	0.9	0.0	0.3	-1.0	0.3	0.8	0.2	0.2	0.2	0.2
Illnesses of siblings: Diabetes	0.4	0.4	1.8	-0.0	1.3	0.1	0.2	-1.0	0.4	-1.2	0.2	0.4	0.6	0.5	0.4	0.4
Commuting to job workplace: Walk	0.4	0.4	1.4	-0.4	-1.2	-0.5	-0.9	-0.3	-0.5	0.5	-0.9	-0.6	-0.6	-0.6	-0.6	-0.5
Average weekly champagne plus white wine intake	0.4	0.5	1.1	-0.4	-0.2	-0.3	-0.6	-0.8	-1.0	-1.0	-0.7	-1.0	-0.5	-0.7	-0.6	-0.7
Guilty feelings	0.4	0.5	1.5	1.1	1.2	1.1	0.6	0.5	0.1	-0.2	1.1	0.5	0.5	0.6	0.6	0.3
Ever taken oral contraceptive pill	0.4	0.5	0.8	-0.9	-0.3	-0.8	-0.6	-0.7	-0.7	-0.9	-0.6	-0.9	-0.5	-0.7	-0.7	-0.7
Risk taking	0.4	0.5	1.1	0.5	0.7	0.5	1.0	0.4	0.9	0.4	0.7	0.6	0.9	0.8	0.8	1.0
Diastolic blood pressure, automated reading	0.4	1.3	2.2	1.2	0.6	1.2	1.0	1.3	1.3	1.5	1.0	1.4	1.0	1.1	1.0	1.0
Basal cell carcinoma (self-reported)	0.4	0.5	1.6	-1.1	-1.3	-1.2	-0.6	0.0	-0.3	0.5	-0.2	-0.6	-0.5	-0.4	-0.4	-0.3
Heart attack/myocardial infarction (self-reported)	0.4	0.5	1.3	-1.1	-0.5	-1.1	-0.7	-1.0	-0.5	-0.7	-0.7	-0.9	-0.2	-0.4	-0.4	-0.3
Depressed Affect (Nagel 2018)	0.3	0.5	2.6	0.6	-1.0	0.4	-0.4	1.5	-0.2	1.6	0.6	-0.2	-0.4	-0.1	-0.1	-0.3
Alzheimer’s Disease (including proxy)	0.3	0.4	1.4	0.2	1.0	0.4	0.6	-1.0	0.7	-1.2	-0.5	0.9	0.2	0.2	-0.0	0.2
Number of treatments/medications taken	0.3	0.6	1.1	0.8	1.0	0.9	0.7	-0.2	0.9	0.0	0.4	0.8	0.9	0.8	0.7	0.9
Sensitivity / hurt feelings	0.3	0.5	0.8	0.6	0.7	0.6	0.8	0.4	0.6	0.3	0.7	0.4	0.9	0.9	0.9	0.9
Average weekly fortified wine intake	0.3	0.3	0.7	-0.4	-0.6	-0.5	-0.8	-0.1	-0.8	-0.1	-0.0	-0.7	-0.5	-0.5	-0.5	-0.7
Alcohol usually taken with meals	0.3	0.4	1.9	0.1	1.4	0.2	0.5	0.4	0.6	-0.6	0.4	1.2	0.5	0.6	0.6	0.3
Pain all over the body in last month	0.3	0.3	0.9	-0.1	0.0	-0.1	-0.7	-0.9	-0.7	-0.7	-0.5	-0.6	-0.3	-0.4	-0.4	-0.5
Pulse wave reflection index	0.3	0.4	1.0	-0.9	-1.0	-1.0	-0.8	-0.2	-0.4	0.2	-0.7	-0.5	-0.4	-0.3	-0.4	-0.4
Medication: Amlodipine	0.3	0.4	0.9	0.9	0.9	0.9	0.5	0.2	0.3	0.1	0.5	0.3	0.8	0.7	0.7	0.6
Body fat percentage	0.3	1.1	2.2	1.4	0.1	1.4	1.4	1.5	1.2	1.5	0.9	1.3	0.4	0.4	0.5	0.7
Alcohol intake frequency.	0.3	0.6	1.2	-0.2	-1.0	-0.2	-0.8	-0.0	-1.1	0.0	-0.6	-1.0	-1.1	-0.9	-0.8	-0.9
Suffer from ‘nerves’	0.3	0.4	1.2	-1.0	-1.1	-1.0	-0.3	0.5	-0.6	0.3	-0.1	-0.9	-0.6	-0.5	-0.4	-0.5
Had major operations	0.3	0.3	0.7	-0.3	0.0	-0.2	-0.3	-0.3	-0.4	-0.8	-0.6	0.1	-0.8	-0.8	-0.7	-0.8
Qualifications: NVQ or HND or HNC or equivalent	0.3	0.3	1.0	-0.2	-1.0	-0.2	-0.5	-0.1	-0.4	0.3	-0.8	-0.4	-0.7	-0.8	-0.8	-0.6
Medication for cholesterol	0.3	0.4	1.3	0.8	0.0	0.7	0.6	1.0	0.6	1.1	0.7	0.6	0.4	0.5	0.5	0.5
Medication: Gliclazide	0.3	0.3	1.3	-0.1	0.5	-0.1	0.6	0.6	0.8	0.1	-0.0	1.1	0.4	0.5	0.5	0.5
Miserableness	0.3	0.5	1.1	1.0	0.2	1.0	0.5	0.8	0.5	1.0	1.0	0.6	0.4	0.6	0.5	0.5
Leg fat percentage (left)	0.3	1.3	3.3	1.3	-0.0	1.4	1.3	1.5	1.3	1.8	1.0	1.2	0.5	0.5	0.5	0.8
Leg fat mass (left)	0.3	1.0	2.2	1.2	0.2	1.3	1.2	1.2	1.3	1.5	0.9	1.1	0.5	0.5	0.5	0.8
Alzheimer’s Disease (in mother)	0.2	0.2	0.7	0.3	0.8	0.3	0.3	-0.5	0.4	-0.9	-0.3	0.2	0.2	0.3	0.1	0.2
BMI	0.2	1.3	4.5	-0.6	-2.1	-0.7	-1.0	0.6	-0.9	1.6	-0.4	0.4	-1.3	-1.3	-1.1	-1.2
Cardiovascular Disease	0.2	0.5	1.1	0.8	0.7	0.8	0.3	-0.3	0.5	0.6	0.7	0.5	1.0	0.8	0.9	0.9
Type 2 Diabetes (T2D) (2018)	0.2	0.3	0.7	-0.0	0.4	-0.0	0.4	0.3	0.7	0.5	0.3	0.7	0.8	0.7	0.8	0.8
Frequency of depressed mood in last 2 weeks	0.2	0.3	1.2	0.1	-1.1	-0.0	-0.6	0.5	-0.6	0.9	0.3	-0.7	-0.6	-0.4	-0.4	-0.5
Trunk fat percentage	0.2	0.8	1.6	1.2	0.1	1.3	1.2	1.2	1.0	1.2	0.6	1.1	0.2	0.2	0.3	0.5
Townsend deprivation index at recruitment	0.2	0.3	1.6	-0.7	-1.3	-0.7	-0.2	0.0	-0.3	0.5	-0.3	-0.9	-0.4	-0.4	-0.4	-0.2
Fed-up feelings	0.2	0.4	2.1	0.7	-0.8	0.6	-0.1	0.9	-0.1	1.4	0.5	-0.1	-0.0	0.1	0.1	0.1
Frequency of unenthusiasm / disinterest in last 2 weeks	0.2	0.2	0.7	0.8	-0.1	0.8	0.2	0.4	0.1	0.8	0.6	0.0	0.2	0.4	0.4	0.4
Serious illness, injury or assault to yourself	0.2	0.3	1.4	-0.2	-0.3	-0.1	-0.2	-1.2	-0.3	-0.6	-0.8	-1.0	0.0	-0.1	-0.2	0.1
Trunk fat mass	0.2	1.0	2.0	1.3	0.3	1.4	1.4	1.1	1.2	1.2	0.7	1.1	0.4	0.4	0.4	0.7
Waist circumference	0.2	0.7	1.9	1.1	-0.1	1.1	0.9	1.1	0.8	1.4	0.7	0.7	0.3	0.3	0.3	0.5
Frequency of tenseness / restlessness in last 2 weeks	0.2	0.3	1.2	0.3	-1.1	0.2	-0.2	0.6	-0.5	0.9	0.3	-0.6	-0.8	-0.5	-0.5	-0.4
Had menopause	0.2	0.3	0.9	-0.0	0.0	0.0	-0.3	-0.9	-0.6	-0.9	-0.5	-0.9	-0.4	-0.4	-0.4	-0.3
Medication: Ramipril	0.2	0.3	0.9	0.5	0.7	0.5	0.2	-0.4	0.4	0.1	0.4	0.2	0.9	0.7	0.6	0.6
Neuroticism score	0.2	0.4	1.3	0.6	-0.2	0.6	0.7	0.7	0.4	1.1	1.0	0.0	0.5	0.4	0.4	0.6
Weight	0.2	0.9	2.5	1.5	0.4	1.6	1.3	0.8	1.2	1.1	0.6	0.9	0.6	0.5	0.5	0.8
Arm fat percentage (right)	0.2	0.7	2.1	1.1	-0.3	1.1	0.9	1.2	0.8	1.4	0.6	0.9	0.0	0.1	0.1	0.4
Hair/balding pattern: Pattern 3	0.2	0.3	0.7	0.8	0.1	0.7	0.3	0.7	0.2	0.8	0.9	0.5	0.3	0.4	0.4	0.4
Qualifications: A levels/AS levels or equivalent	0.2	0.4	1.3	0.2	1.1	0.4	0.9	-0.3	0.9	-0.6	0.6	0.6	0.6	0.5	0.5	0.7
Pulse wave Arterial Stiffness index	0.2	0.3	0.6	-0.4	-0.8	-0.4	-0.6	-0.3	-0.5	0.1	-0.6	-0.5	-0.5	-0.5	-0.5	-0.5
Standing height	0.2	1.8	4.3	0.9	2.1	1.2	2.1	-0.8	1.6	-1.1	0.3	0.9	1.5	1.1	1.1	1.6
Tense / ‘highly strung’	0.2	0.3	0.9	0.5	0.6	0.6	1.0	0.1	0.4	-0.1	0.6	0.0	0.5	0.4	0.4	0.6
Glaucoma (self-reported)	0.2	0.2	1.1	0.8	-0.2	0.7	-0.2	0.8	0.2	1.1	0.1	0.5	0.1	0.2	0.1	0.0
Pulse wave peak to peak time	0.2	0.3	0.6	0.5	0.8	0.5	0.7	0.3	0.5	-0.1	0.7	0.5	0.5	0.5	0.5	0.5
Neck or shoulder pain in last month	0.2	0.3	1.5	-0.2	-0.8	-0.1	-0.0	-0.9	-0.3	0.0	-0.5	-1.2	-0.2	-0.4	-0.4	0.0
Whole body fat mass	0.2	0.8	1.7	1.1	0.1	1.2	1.2	1.2	1.1	1.3	0.7	1.0	0.3	0.3	0.3	0.6
Chest pain or discomfort	0.2	0.2	0.7	-0.8	-0.8	-0.8	-0.3	-0.2	-0.3	0.1	-0.2	-0.8	-0.1	-0.1	-0.1	-0.0
Illness, injury, bereavement, stress in last 2 years	0.2	0.2	1.2	-0.4	-0.6	-0.4	-0.3	1.1	-0.2	0.7	0.2	0.3	-0.5	-0.2	-0.2	-0.4
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.2	0.2	0.5	-0.6	-0.3	-0.6	-0.5	-0.7	-0.4	-0.4	-0.1	-0.7	-0.2	-0.3	-0.3	-0.3
Arm fat percentage (left)	0.2	0.7	1.7	1.2	-0.1	1.3	0.9	1.2	0.8	1.3	0.6	1.0	-0.0	0.0	0.1	0.3
Ever had bowel cancer screening	0.2	0.2	1.3	1.1	0.1	1.0	-0.2	0.2	-0.3	0.5	0.4	0.0	-0.0	0.2	0.1	-0.0
Qualifications: nursing, teaching	0.2	0.3	0.9	0.9	0.5	0.9	0.7	0.7	0.4	0.3	0.9	0.6	0.0	0.1	0.1	0.1
Eye problems/disorders: Cataract	0.2	0.2	0.9	-0.5	-0.2	-0.4	-0.1	-0.7	-0.5	-0.6	-0.3	-0.9	-0.1	-0.2	-0.2	-0.1
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.2	0.2	0.3	0.5	0.4	0.4	0.4	0.4	0.3	0.4	0.5	0.5	0.4	0.5	0.5	0.5
Asthma (self-reported)	0.2	0.4	2.0	0.2	1.4	0.4	0.8	-0.3	0.3	-1.4	-0.0	0.5	0.3	0.1	0.2	0.2
Osteoarthritis (self-reported)	0.2	0.2	0.7	0.8	0.7	0.8	0.6	-0.4	0.4	-0.2	0.3	0.3	0.5	0.3	0.3	0.5
Arm fat mass (left)	0.2	0.8	2.0	1.3	0.1	1.4	1.1	1.1	1.0	1.3	0.7	1.0	0.2	0.2	0.2	0.5
Tinnitus: Yes, now most or all of the time	0.2	0.2	0.8	-0.6	-0.9	-0.7	-0.6	-0.4	0.1	0.5	-0.4	-0.1	-0.2	-0.2	-0.3	-0.1
Commuting to job workplace: Public transport	0.2	0.2	0.6	0.4	-0.1	0.4	0.5	0.2	0.6	0.7	0.3	0.1	0.6	0.5	0.5	0.7
Eye problems/disorders: Glaucoma	0.2	0.3	0.9	0.9	0.2	0.9	-0.1	0.8	0.1	0.8	0.3	0.6	0.2	0.3	0.3	0.0
Pain type(s) experienced in last month: Hip pain	0.2	0.3	0.9	-1.0	-1.0	-1.0	-0.1	0.4	-0.2	0.2	-0.5	-0.2	-0.5	-0.4	-0.4	-0.3
High cholesterol (Self-reported)	0.2	0.3	0.8	-0.9	-0.7	-0.8	-0.3	-0.6	-0.2	-0.2	-0.6	-0.7	-0.3	-0.3	-0.3	-0.1
Ever depressed for a whole week	0.2	0.2	0.6	0.0	0.0	0.1	0.6	0.2	0.8	0.6	0.4	0.3	0.6	0.6	0.6	0.8
Myopia	0.2	0.3	1.8	1.3	0.2	1.4	0.5	0.4	0.0	0.4	0.4	0.2	-0.0	-0.1	-0.1	0.0
Medication: Omeprazole (e.g. Zanprol)	0.2	0.2	1.4	0.1	-1.0	0.1	-0.1	0.2	0.1	1.2	0.2	-0.3	-0.1	-0.1	-0.1	0.1
Depression (Nagel 2018)	0.1	0.2	0.5	0.6	-0.3	0.5	-0.7	-0.1	-0.5	0.3	0.1	-0.2	-0.5	-0.3	-0.4	-0.5
Worry (Nagel 2018)	0.1	0.2	0.5	0.3	0.1	0.2	0.2	0.7	0.3	0.6	0.7	-0.5	0.5	0.5	0.5	0.5
Lupus	0.1	0.2	1.1	-0.1	-0.3	-0.2	-0.2	1.0	-0.0	0.8	0.4	0.3	-0.1	0.2	0.1	-0.1
Blood White Count	0.1	0.7	3.3	0.8	-0.5	0.7	0.5	1.7	0.2	1.8	0.5	1.2	0.0	-0.2	0.2	0.1
Height	0.1	1.2	5.3	-0.0	1.2	0.3	1.3	-2.3	0.8	-2.2	-0.9	-0.2	0.6	0.0	0.0	0.8
Lung FEV1/FVC ratio	0.1	0.6	1.9	-0.3	0.6	-0.3	1.1	-0.1	1.1	0.0	0.2	1.4	1.0	0.8	0.8	1.1
Average weekly spirits intake	0.1	0.1	0.3	-0.3	-0.0	-0.2	0.4	-0.5	0.4	-0.0	-0.2	-0.2	0.5	0.3	0.2	0.5
Other serious medical condition/disability diagnosed by doctor	0.1	0.2	1.0	0.6	0.2	0.6	0.1	-1.0	0.1	-0.2	-0.3	-0.3	0.3	0.2	0.1	0.5
Ever used hormone-replacement therapy (HRT)	0.1	0.1	0.5	-0.1	-0.0	-0.1	-0.1	-0.7	-0.2	-0.4	-0.1	-0.5	0.0	-0.1	-0.1	0.0
Medication: Co-codamol	0.1	0.1	0.5	-0.1	0.6	0.0	0.5	-0.5	0.3	-0.7	-0.1	0.1	0.3	0.2	0.2	0.4
Diabetes (mother)	0.1	0.2	0.6	0.6	0.2	0.6	0.3	0.3	0.6	0.4	-0.1	0.7	0.1	0.2	0.2	0.3
Impedance of leg (right)	0.1	0.7	2.3	-0.1	0.8	-0.0	1.5	0.5	1.2	-0.1	0.5	0.9	0.9	0.8	0.8	1.1
Current tobacco smoking	0.1	0.1	0.6	-0.5	-0.5	-0.4	0.3	-0.4	0.0	0.1	0.0	-0.7	0.3	0.0	0.1	0.4
Taking other prescription medications	0.1	0.1	0.2	-0.2	-0.4	-0.2	0.4	0.3	0.5	0.5	0.0	0.3	-0.0	-0.1	-0.1	0.2
Diverticular disease/diverticulitis (self-reported)	0.1	0.2	0.6	0.0	-0.1	0.0	0.6	0.6	0.3	0.5	0.8	0.0	0.2	0.3	0.3	0.3
Body mass index (BMI)	0.1	0.6	2.9	1.0	-0.7	1.0	0.4	1.2	0.4	1.7	0.5	0.5	-0.2	-0.1	-0.1	0.1
Impedance of leg (left)	0.1	0.6	1.7	-0.3	1.0	-0.2	1.3	0.2	1.1	-0.4	0.4	0.9	0.9	0.8	0.9	1.0
Nervous feelings	0.1	0.2	0.7	-0.3	-0.8	-0.4	-0.3	0.2	-0.2	0.8	0.4	-0.7	0.0	0.1	0.0	0.0
Diabetes (self-reported)	0.1	0.2	0.4	0.1	0.4	0.1	0.3	-0.1	0.6	0.1	0.2	0.4	0.6	0.6	0.6	0.6
Hip circumference	0.1	0.3	0.8	0.2	-0.8	0.2	-0.1	0.2	-0.2	0.3	-0.4	-0.2	-0.8	-0.9	-0.8	-0.6
Worrier / anxious feelings	0.1	0.1	0.5	-0.1	-0.4	-0.2	-0.2	0.3	-0.0	0.7	0.5	-0.3	0.2	0.4	0.3	0.2
Falls in the last year	0.1	0.1	0.3	0.0	-0.2	-0.1	-0.5	-0.5	-0.2	0.2	-0.1	-0.5	0.3	0.4	0.3	0.3
Noisy workplace	0.1	0.1	0.5	0.5	0.7	0.5	0.2	-0.2	0.1	-0.4	0.2	0.2	0.3	0.3	0.3	0.2
Asthma	0.1	0.2	1.5	-0.1	0.8	0.0	0.3	-0.4	-0.1	-1.2	-0.2	-0.0	-0.1	-0.2	-0.1	-0.2
Medication: Lansoprazole	0.1	0.1	0.5	-0.7	-0.2	-0.7	0.1	0.1	-0.1	-0.3	0.1	-0.2	-0.3	-0.3	-0.3	-0.3
Arm fat mass (right)	0.1	0.6	1.7	1.0	-0.3	1.1	0.9	1.0	0.8	1.3	0.4	0.7	-0.0	-0.0	0.0	0.3
Hair/balding pattern: Pattern 4	0.1	0.1	0.6	0.2	0.5	0.2	-0.2	-0.5	-0.4	-0.8	-0.5	-0.1	0.1	0.0	0.0	-0.1
Gout (self-reported)	0.1	0.1	0.3	0.5	0.4	0.5	0.2	0.1	0.2	0.0	0.4	0.3	0.0	0.0	0.0	0.0
Medication: Ventolin 100micrograms inhaler	0.1	0.2	0.9	0.0	0.2	0.0	0.3	0.9	0.2	0.5	0.6	0.3	0.2	0.4	0.4	0.2
Number of children fathered	0.1	0.2	0.6	-0.8	-0.0	-0.8	-0.7	-0.0	-0.2	-0.2	-0.4	0.1	-0.1	-0.0	-0.1	-0.4
Health satisfaction	0.1	0.1	0.3	0.5	-0.4	0.4	-0.2	-0.2	-0.2	0.5	-0.1	-0.1	-0.0	0.0	-0.0	0.1
Qualifications: College or University degree	0.1	0.3	1.1	0.5	1.1	0.6	0.7	0.0	0.4	-0.6	0.4	0.4	0.3	0.3	0.4	0.3
Eye problems/disorders: None of the above	0.1	0.1	0.2	-0.4	-0.4	-0.4	-0.3	0.2	0.1	0.3	-0.2	0.3	-0.2	-0.2	-0.2	-0.2
Mouth/teeth dental problems: Loose teeth	0.1	0.1	0.3	-0.2	0.4	-0.2	0.6	0.4	0.5	-0.0	0.5	0.4	0.3	0.3	0.3	0.3
Migraine (self-reported)	0.1	0.1	0.3	-0.3	0.4	-0.3	-0.4	-0.5	-0.1	-0.6	-0.3	0.0	0.2	0.2	0.1	-0.0
Medication: Allopurinol	0.1	0.1	0.4	0.6	0.3	0.6	-0.0	-0.4	-0.1	-0.2	0.1	-0.0	0.1	0.0	0.0	0.0
Pulse rate, automated reading	0.1	0.4	2.1	-0.4	-1.4	-0.5	-0.3	0.5	-0.2	1.0	-0.5	-0.5	-0.5	-0.6	-0.6	-0.4
Overall health rating	0.1	0.2	0.9	0.4	-0.6	0.3	-0.1	0.3	-0.2	0.9	0.5	-0.4	0.2	0.2	0.1	0.2
Commuting to job workplace: Car/motor vehicle	0.1	0.1	0.4	0.3	0.4	0.3	-0.2	0.0	-0.6	-0.6	0.2	-0.1	-0.4	-0.2	-0.2	-0.4
Knee pain experienced in last month	0.1	0.1	0.8	0.2	-0.6	0.2	0.3	0.3	0.4	0.9	-0.0	0.1	0.0	0.1	0.1	0.3
Forced expiratory volume in 1-second (FEV1), predicted	0.1	0.2	0.6	0.1	0.1	0.1	0.5	-0.2	0.8	0.4	0.2	0.1	0.7	0.6	0.5	0.8
Average weekly red wine intake	0.1	0.1	0.5	-0.3	0.5	-0.3	-0.5	-0.1	-0.2	-0.7	0.2	0.3	-0.4	-0.2	-0.2	-0.5
Handedness (chirality/laterality): Left-handed	0.1	0.1	0.3	-0.1	-0.2	-0.1	0.1	-0.0	-0.2	0.2	0.1	-0.5	0.4	0.3	0.3	0.3
Long-standing illness, disability or infirmity	0.1	0.2	1.5	0.4	0.2	0.5	0.0	-1.2	-0.1	-0.6	-0.4	-0.5	0.1	-0.2	-0.2	0.1
Ever had stillbirth, spontaneous miscarriage or termination	0.1	0.1	0.4	0.3	0.4	0.4	0.5	-0.6	0.1	-0.6	-0.3	-0.1	0.1	-0.2	-0.1	0.1
Breast cancer (self-reported)	0.1	0.1	0.5	0.4	0.3	0.4	0.4	-0.7	0.4	-0.2	-0.2	-0.0	0.4	0.3	0.2	0.5
Smoking status: Current	0.1	0.1	0.6	-0.4	-0.4	-0.4	0.4	-0.4	0.1	-0.0	0.1	-0.7	0.3	0.0	0.0	0.4
Medication: Blood pressure	0.1	0.3	1.2	0.5	1.1	0.5	0.0	-0.6	0.0	-0.9	-0.2	0.3	0.3	0.3	0.2	0.1
Medication: Bendroflumethiazide	0.1	0.2	0.5	0.4	0.2	0.4	0.4	0.7	0.3	0.6	0.5	0.2	0.4	0.5	0.5	0.4
Average weekly beer plus cider intake	0.1	0.1	0.3	-0.5	-0.2	-0.5	0.3	-0.1	0.2	0.1	0.2	-0.3	0.3	0.1	0.1	0.2
Irritability	0.1	0.2	1.6	-0.3	0.2	-0.2	0.2	-1.3	0.2	-0.7	-0.2	-0.7	0.3	0.1	0.0	0.4
Impedance of whole body	0.1	0.3	0.7	-0.6	0.6	-0.5	0.8	-0.2	0.6	-0.8	-0.1	0.5	0.4	0.3	0.3	0.5
Arm predicted mass (left)	0.1	0.3	1.1	0.9	0.4	1.1	0.8	0.1	0.6	0.3	0.3	0.3	0.4	0.3	0.3	0.5
Bipolar Disorder (2018)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Bipolar Disorder or Schizophrenia	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Schizophrenia (2018)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Schizophrenia vs Biploar Disorder	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Major Depression (MDD)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Age at First Birth	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Bipolar Disorder (2011)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Body Mass Index (BMI) (2010)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Coronary Artery Disease (CAD)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Crohns Disease (2012)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Mean Putamen Volume	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Fasting Glucose	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
HbA1C	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
HDL Cholesterol	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
LDL Cholesterol	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Primary Biliary Cirrhosis	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Rheumatoid Arthritis	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Schizophrenia (2014)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Triglycerides	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Type 2 Diabetes (T2D) (2012)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Ulcerative Colitis	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Blood Red Count	0.0	0.4	1.4	0.7	-0.1	0.8	0.9	1.2	0.2	0.9	0.5	0.7	-0.1	-0.3	-0.1	0.0
Tanning	0.0	0.4	1.1	0.3	0.8	0.3	0.1	1.0	0.4	0.3	0.9	-0.1	0.7	0.9	0.8	0.5
Hand grip strength (left)	0.0	0.1	0.3	0.2	0.3	0.2	0.3	0.5	0.1	0.1	-0.1	0.2	0.2	0.2	0.2	0.1
Relative age of first facial hair	0.0	0.1	0.3	-0.3	0.3	-0.3	0.3	0.4	-0.0	-0.6	-0.3	0.4	-0.2	-0.3	-0.2	-0.3
Medication: Metformin	0.0	0.0	0.2	-0.3	-0.0	-0.3	-0.2	0.0	0.1	-0.0	-0.4	0.1	0.1	0.1	0.1	0.1
Leg fat-free mass (left)	0.0	0.1	0.5	0.6	-0.1	0.7	0.1	-0.5	-0.1	-0.1	-0.3	-0.3	-0.3	-0.5	-0.4	-0.2
Leg predicted mass (left)	0.0	0.1	0.5	0.6	-0.1	0.7	0.1	-0.4	-0.1	-0.1	-0.3	-0.3	-0.3	-0.5	-0.5	-0.2
Number of incorrect matches in round	0.0	0.1	0.3	-0.3	0.4	-0.3	-0.1	-0.4	0.1	-0.6	0.2	0.2	-0.0	0.0	0.0	-0.0
Hearing difficulty/problems with background noise	0.0	0.1	0.3	0.2	0.3	0.3	0.1	-0.1	-0.2	-0.2	0.6	-0.3	-0.0	0.1	0.1	0.0
Ever unenthusiastic/disinterested for a whole week	0.0	0.0	0.2	-0.0	-0.4	-0.0	-0.2	-0.1	-0.1	0.3	-0.1	-0.4	-0.1	-0.0	-0.1	-0.0
Impedance of arm (right)	0.0	0.2	1.0	-0.7	0.2	-0.6	0.3	-0.6	0.1	-1.0	-0.5	-0.0	-0.1	-0.2	-0.1	0.1
Trunk fat-free mass	0.0	0.2	0.5	0.4	0.4	0.6	0.5	-0.7	0.2	-0.6	-0.2	-0.2	0.1	-0.1	-0.1	0.2
Happiness	0.0	0.0	0.1	-0.1	0.1	-0.1	-0.1	-0.2	-0.2	-0.3	-0.0	-0.2	-0.1	-0.0	0.0	-0.1
Impedance of arm (left)	0.0	0.2	1.3	-0.6	0.3	-0.5	0.1	-0.6	-0.1	-1.1	-0.6	0.1	-0.2	-0.3	-0.2	-0.1
Trunk predicted mass	0.0	0.2	0.5	0.4	0.5	0.6	0.5	-0.7	0.3	-0.6	-0.2	-0.2	0.2	-0.1	-0.0	0.2
Exposure to tobacco smoke at home	0.0	0.1	0.2	0.2	0.0	0.2	0.5	0.4	0.2	0.1	-0.1	0.3	0.1	-0.0	0.0	0.1
Ever highly irritable/argumentative for 2 days	0.0	0.0	0.1	-0.1	-0.1	-0.2	-0.1	0.3	-0.1	0.2	0.3	0.0	0.0	0.0	0.0	-0.1
Headache pain in last month	0.0	0.1	0.2	-0.1	0.3	-0.2	-0.1	0.0	0.2	-0.0	0.2	0.3	0.3	0.5	0.4	0.3
Chronic bronchitis/emphysema (mother)	0.0	0.0	0.1	0.3	-0.2	0.3	-0.0	0.1	-0.1	0.4	0.2	-0.3	0.1	0.1	0.1	0.1
Arm fat-free mass (right)	0.0	0.2	1.2	1.0	0.6	1.1	0.6	-0.3	0.4	-0.2	0.1	0.1	0.2	0.1	0.1	0.3
Comparative body size at age 10	0.0	0.1	0.2	0.1	0.4	0.2	0.0	0.2	-0.2	-0.4	0.2	0.1	-0.2	-0.2	-0.1	-0.3
Arm predicted mass (right)	0.0	0.2	0.8	0.8	0.5	0.9	0.4	-0.3	0.3	-0.2	0.1	0.0	0.1	-0.0	-0.1	0.1
Whole body fat-free mass	0.0	0.1	0.5	0.5	0.2	0.7	0.3	-0.7	0.1	-0.4	-0.3	-0.3	-0.1	-0.3	-0.3	-0.0
Leg fat-free mass (right)	0.0	0.2	0.5	0.6	0.1	0.7	-0.0	-0.7	-0.1	-0.3	-0.3	-0.4	-0.2	-0.3	-0.4	-0.2
Whole body water mass	0.0	0.2	0.7	0.7	0.4	0.8	0.3	-0.6	0.1	-0.4	-0.2	-0.2	-0.0	-0.2	-0.2	0.0
Leg predicted mass (right)	0.0	0.2	0.7	0.4	0.0	0.6	-0.2	-0.8	-0.3	-0.5	-0.4	-0.5	-0.3	-0.5	-0.5	-0.3
Hearing aid user	0.0	0.1	0.2	0.4	0.3	0.4	0.1	0.1	0.2	0.1	0.2	0.4	0.1	0.0	0.0	0.0
Basal metabolic rate	0.0	0.1	0.7	0.7	0.2	0.8	0.4	-0.4	0.3	-0.2	-0.1	-0.1	-0.0	-0.2	-0.2	0.1
Arm fat-free mass (left)	0.0	0.2	1.0	0.9	0.4	1.0	0.6	-0.1	0.4	0.1	0.1	0.1	0.2	0.1	0.1	0.3
Commuting to job workplace: Cycle	0.0	0.0	0.1	-0.1	-0.1	-0.0	0.1	-0.2	-0.2	-0.2	-0.0	-0.4	-0.1	-0.2	-0.2	-0.0
Pain experienced in last month	0.0	0.1	0.3	-0.3	-0.0	-0.4	-0.5	0.1	-0.3	-0.1	0.0	-0.1	-0.2	-0.1	-0.1	-0.4

Hub : Genes

LOC441869

Models

Trait associations