[Hub]/) : Traits : Comparative height size at age 10 :

chr10:69,348,758-71,725,020

Best TWAS P=6.73e-16 · Best GWAS P=9.79e-15 conditioned to 0

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex PBLD 0.07 0.09 lasso 3 0.08 4.8e-10 -5.6 -5.7 1.0e-08 -0.38 1.00 0.00 FALSE
2 GTEx Adipose Subcutaneous PBLD 0.14 0.12 lasso 3 0.09 3.8e-08 -5.6 -5.7 1.2e-08 -0.38 1.00 0.00 TRUE
3 GTEx Adipose Subcutaneous DNA2 0.31 0.23 enet 10 0.25 2.3e-20 -4.7 5.3 8.7e-08 0.31 1.00 0.00 FALSE
4 GTEx Adipose Visceral Omentum DNA2 0.32 0.18 lasso 9 0.20 1.9e-10 -5.6 5.5 4.7e-08 0.29 1.00 0.00 FALSE
5 GTEx Adrenal Gland DNA2 0.16 0.12 lasso 6 0.10 2.2e-04 -4.7 5.3 1.0e-07 0.30 0.45 0.14 FALSE
6 GTEx Artery Aorta PBLD 0.14 0.10 lasso 8 0.06 3.1e-04 -5.6 -6.0 2.0e-09 -0.43 0.97 0.02 FALSE
7 GTEx Artery Aorta DNA2 0.22 0.17 lasso 6 0.16 5.1e-09 -4.7 5.5 5.2e-08 0.29 1.00 0.00 FALSE
8 GTEx Artery Coronary DNA2 0.12 0.12 lasso 5 0.12 5.3e-05 -5.7 6.2 6.1e-10 0.32 0.26 0.32 FALSE
9 GTEx Artery Tibial PBLD 0.06 0.09 lasso 2 0.07 2.5e-06 -5.6 -5.6 1.8e-08 -0.38 0.91 0.02 FALSE
10 GTEx Artery Tibial DNA2 0.10 0.09 lasso 3 0.11 4.4e-09 -5.7 5.5 4.3e-08 0.29 0.99 0.00 FALSE
11 GTEx Brain Caudate basal ganglia PBLD 0.17 0.14 lasso 16 0.13 1.2e-04 -5.6 -6.4 2.1e-10 -0.48 0.59 0.11 TRUE
12 GTEx Brain Cerebellar Hemisphere DNA2 0.28 0.29 lasso 11 0.27 1.4e-07 -4.8 5.3 1.4e-07 0.29 0.70 0.05 FALSE
13 GTEx Brain Cerebellum SLC25A16 0.22 0.15 lasso 9 0.19 2.2e-06 -4.8 -5.3 9.8e-08 -0.28 0.30 0.11 FALSE
14 GTEx Brain Frontal Cortex BA9 PBLD 0.15 0.00 lasso 3 0.01 1.6e-01 -5.6 -5.8 7.9e-09 -0.43 0.27 0.20 FALSE
15 GTEx Brain Hypothalamus SLC25A16 0.20 0.19 lasso 5 0.14 3.6e-04 -5.6 -5.8 7.8e-09 -0.35 0.10 0.34 FALSE
16 GTEx Brain Nucleus accumbens basal ganglia PBLD 0.20 0.13 lasso 2 0.09 1.7e-03 -5.6 -5.6 1.8e-08 -0.38 0.12 0.50 FALSE
17 GTEx Breast Mammary Tissue DNA2 0.30 0.26 lasso 7 0.26 8.2e-14 -4.6 5.2 2.7e-07 0.28 1.00 0.00 FALSE
18 GTEx Breast Mammary Tissue (Male) DNA2 0.32 0.14 lasso 5 0.07 1.2e-02 -4.6 5.2 1.9e-07 0.29 0.33 0.07 FALSE
19 GTEx Breast Mammary Tissue (Female) DNA2 0.15 0.10 lasso 3 0.07 3.6e-03 -4.6 5.3 9.8e-08 0.29 0.19 0.07 FALSE
20 GTEx Cells EBV-transformed lymphocytes DNA2 0.32 0.14 lasso 2 0.10 2.9e-04 -5.6 5.6 2.0e-08 0.30 0.44 0.08 FALSE
21 GTEx Cells Transformed fibroblasts DNA2 0.16 0.09 lasso 8 0.14 7.6e-11 -4.4 5.6 2.0e-08 0.30 1.00 0.00 TRUE
22 GTEx Colon Transverse DNA2 0.20 0.17 lasso 4 0.14 2.5e-07 -5.7 5.6 1.8e-08 0.29 0.79 0.21 TRUE
23 GTEx Esophagus Muscularis PBLD 0.07 0.03 lasso 7 0.02 1.5e-02 -5.6 -5.4 6.4e-08 -0.40 0.67 0.07 FALSE
24 GTEx Esophagus Muscularis DNA2 0.35 0.24 enet 10 0.33 9.3e-21 -5.7 5.5 3.6e-08 0.29 1.00 0.00 FALSE
25 GTEx Esophagus Muscularis RUFY2 0.06 0.02 lasso 6 0.02 2.0e-02 -4.8 -5.3 1.0e-07 -0.43 0.18 0.04 FALSE
26 GTEx Heart Atrial Appendage PBLD 0.08 0.02 lasso 2 0.02 6.1e-02 -7.1 -8.1 6.7e-16 -0.46 0.05 0.57 TRUE
27 GTEx Heart Left Ventricle DNA2 0.10 0.12 lasso 6 0.11 3.0e-06 -4.7 5.1 2.9e-07 0.28 0.87 0.06 FALSE
28 GTEx Liver DNA2 0.26 0.15 lasso 7 0.19 6.5e-06 -4.8 5.2 2.4e-07 0.26 0.29 0.09 FALSE
29 GTEx Lung DNA2 0.22 0.17 enet 12 0.24 3.9e-18 -5.7 5.3 1.1e-07 0.29 1.00 0.00 FALSE
30 GTEx Muscle Skeletal PBLD 0.11 0.10 lasso 12 0.12 5.1e-12 -4.6 -5.8 8.5e-09 -0.47 1.00 0.00 FALSE
31 GTEx Muscle Skeletal DNA2 0.18 0.16 lasso 4 0.19 1.7e-18 -4.7 5.3 1.1e-07 0.29 1.00 0.00 FALSE
32 GTEx Ovary DNA2 0.15 0.12 lasso 3 0.06 1.7e-02 -5.8 5.8 5.9e-09 0.32 0.12 0.09 FALSE
33 GTEx Pancreas PBLD 0.18 0.17 enet 6 0.16 3.1e-07 -5.6 -6.0 1.6e-09 -0.31 0.73 0.04 FALSE
34 GTEx Pancreas DNA2 0.12 0.06 enet 9 0.08 4.1e-04 -4.6 5.7 9.3e-09 0.29 0.47 0.11 FALSE
35 GTEx Skin Not Sun Exposed Suprapubic DNA2 0.29 0.16 lasso 14 0.22 2.4e-12 -4.7 5.6 2.2e-08 0.32 1.00 0.00 FALSE
36 GTEx Skin Sun Exposed Lower leg DNA2 0.23 0.15 lasso 6 0.14 1.3e-11 -4.8 5.2 1.8e-07 0.32 1.00 0.00 FALSE
37 GTEx Spleen DNA2 0.35 0.19 lasso 8 0.15 1.3e-04 -5.7 5.2 1.6e-07 0.28 0.18 0.12 FALSE
38 GTEx Stomach DNA2 0.31 0.13 lasso 11 0.19 2.3e-09 -4.7 5.5 3.2e-08 0.29 0.93 0.07 FALSE
39 GTEx Testis SLC25A16 0.24 0.23 lasso 4 0.19 7.3e-09 -4.7 -5.1 2.8e-07 -0.28 0.99 0.00 FALSE
40 GTEx Thyroid DNA2 0.18 0.19 lasso 5 0.19 2.9e-14 -4.7 5.1 3.1e-07 0.28 1.00 0.00 FALSE
41 METSIM Adipose PBLD 0.16 0.15 lasso 12 0.14 6.4e-21 -5.6 -6.2 4.7e-10 -0.40 0.98 0.02 FALSE
42 NTR Blood HKDC1 0.05 0.01 enet 23 0.03 3.7e-10 4.8 -5.3 1.3e-07 -0.13 0.14 0.86 FALSE
43 NTR Blood SLC25A16 0.03 0.02 enet 16 0.03 1.7e-09 -5.7 -6.8 1.3e-11 -0.32 0.68 0.32 TRUE
44 ROSMAP Brain Pre-frontal Cortex PBLD 0.04 0.01 bslmm 388 0.02 1.3e-03 -4.6 -6.4 1.3e-10 -0.54 0.75 0.21 FALSE
45 ROSMAP Brain Pre-frontal Cortex SLC25A16 0.17 0.11 lasso 6 0.15 2.9e-19 -4.6 -6.1 9.3e-10 -0.32 0.90 0.10 FALSE
46 YFS Blood SLC25A16 0.09 0.13 lasso 3 0.13 6.8e-39 -5.7 -6.1 1.3e-09 -0.31 0.88 0.12 FALSE
47 The Cancer Genome Atlas Bladder Urothelial Carcinoma PBLD 0.06 0.07 lasso 2 0.04 2.3e-04 -6.9 -6.9 5.3e-12 -0.44 0.00 0.99 FALSE
48 The Cancer Genome Atlas Bladder Urothelial Carcinoma SLC25A16 0.03 0.02 blup 42 0.02 6.7e-03 -5.6 -5.1 3.1e-07 -0.27 0.08 0.42 FALSE
49 The Cancer Genome Atlas Breast Invasive Carcinoma HKDC1 0.02 0.02 enet 9 0.02 3.9e-05 -5.8 -5.3 9.8e-08 -0.08 0.00 1.00 FALSE
50 The Cancer Genome Atlas Breast Invasive Carcinoma PBLD 0.03 0.01 enet 6 0.02 2.9e-05 -5.6 -5.5 3.1e-08 -0.39 0.62 0.38 FALSE
51 The Cancer Genome Atlas Breast Invasive Carcinoma SLC25A16 0.01 0.02 lasso 2 0.01 5.5e-04 -5.6 -5.7 1.5e-08 -0.30 0.24 0.34 FALSE
52 The Cancer Genome Atlas Cervical Squamous Cell Carcinoma DNA2 0.08 0.09 lasso 1 0.06 7.3e-04 -7.2 7.2 8.0e-13 0.35 0.00 0.98 FALSE
53 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma ATOH7 0.05 0.01 lasso 3 0.02 2.6e-03 -7.0 5.8 4.9e-09 0.45 0.04 0.08 FALSE
54 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma PBLD 0.03 0.03 lasso 9 0.02 1.6e-03 -6.2 -6.2 4.1e-10 -0.53 0.02 0.79 FALSE
55 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma ATOH7 0.16 0.06 enet 15 0.09 3.7e-10 -4.6 6.3 2.7e-10 0.44 0.80 0.19 FALSE
56 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma MYPN 0.05 0.06 lasso 5 0.05 6.4e-06 -5.4 -5.4 7.2e-08 -0.61 0.51 0.48 TRUE
57 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma PBLD 0.10 0.03 lasso 3 0.04 2.2e-05 -6.9 -6.7 2.2e-11 -0.44 0.01 0.99 FALSE
58 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma ATOH7 0.08 0.04 enet 19 0.06 3.1e-04 -4.6 7.6 3.4e-14 0.67 0.12 0.55 FALSE
59 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma DNA2 0.05 0.00 blup 43 0.00 3.0e-01 -5.7 6.4 2.0e-10 0.34 0.01 0.81 FALSE
60 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma PBLD 0.06 0.06 enet 6 0.06 2.5e-04 -5.9 -5.9 4.2e-09 -0.38 0.24 0.28 FALSE
61 The Cancer Genome Atlas Brain Lower Grade Glioma PBLD 0.12 0.18 enet 10 0.18 6.7e-20 -5.6 -6.1 9.7e-10 -0.40 0.21 0.79 FALSE
62 The Cancer Genome Atlas Brain Lower Grade Glioma SLC25A16 0.05 0.01 blup 42 0.02 2.9e-03 -5.7 -5.5 4.9e-08 -0.21 0.06 0.83 FALSE
63 The Cancer Genome Atlas Liver Hepatocellular Carcinoma STOX1 0.21 0.18 blup 51 0.25 6.6e-12 -2.9 -5.3 1.4e-07 0.01 0.53 0.43 FALSE
64 The Cancer Genome Atlas Lung Squamous Cell Carcinoma PBLD 0.02 0.01 blup 76 0.01 1.5e-02 -5.8 -5.8 6.4e-09 -0.44 0.15 0.21 FALSE
65 The Cancer Genome Atlas Lung Squamous Cell Carcinoma SLC25A16 0.02 0.02 enet 8 0.02 7.7e-04 -7.2 -6.8 8.7e-12 -0.34 0.01 0.92 FALSE
66 The Cancer Genome Atlas Pancreatic Adenocarcinoma ATOH7 0.10 -0.01 blup 59 0.04 1.1e-02 -4.6 5.9 3.0e-09 0.63 0.04 0.17 FALSE
67 The Cancer Genome Atlas Pancreatic Adenocarcinoma HKDC1 0.17 0.04 lasso 5 0.07 6.0e-04 -5.1 -5.6 1.7e-08 -0.16 0.05 0.65 TRUE
68 The Cancer Genome Atlas Prostate Adenocarcinoma PBLD 0.03 0.01 blup 76 0.01 1.3e-02 -6.0 -6.6 4.4e-11 -0.47 0.05 0.40 FALSE
69 The Cancer Genome Atlas Rectum Adenocarcinoma STOX1 0.23 0.17 blup 51 0.21 1.2e-05 -5.6 -5.8 6.6e-09 -0.04 0.00 0.94 TRUE
70 The Cancer Genome Atlas Soft Tissue Sarcoma SLC25A16 0.07 0.03 blup 42 0.02 1.7e-02 -7.2 -6.7 1.6e-11 -0.32 0.01 0.94 FALSE
71 The Cancer Genome Atlas Testicular Germ Cell Tumors DNA2 0.14 0.07 blup 43 0.08 8.6e-04 -6.2 -6.4 1.2e-10 -0.31 0.07 0.49 FALSE
72 The Cancer Genome Atlas Thyroid Carcinoma PBLD 0.06 0.09 lasso 2 0.09 1.1e-08 -5.6 -5.8 9.2e-09 -0.38 0.51 0.49 FALSE
73 The Cancer Genome Atlas Thyroid Carcinoma SLC25A16 0.05 0.05 lasso 3 0.04 3.8e-05 -5.7 -5.6 1.9e-08 -0.29 0.06 0.82 FALSE