TWAS hub - HKDC1

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.0670	0.0280	9.1e-03	0.039	0.010	0.018	0.022	0.022	1.3e-05	1.7e-02	2.6e-03	9.1e-04	9.8e-04
2	NTR	Blood	0.0477	0.0120	3.5e-07	0.007	0.024	0.030	0.026	0.025	2.3e-03	2.0e-08	3.7e-10	7.4e-09	1.4e-08
3	TCGA	Breast Invasive Carcinoma	0.0209	0.0085	4.7e-04	0.019	0.019	0.020	NA	0.018	8.1e-05	7.5e-05	3.9e-05	NA	1.1e-04
4	TCGA	Kidney Renal Clear Cell Carcinoma	0.0568	0.0196	4.3e-06	0.019	0.039	0.026	NA	0.019	3.0e-03	3.0e-05	5.9e-04	NA	2.7e-03
5	TCGA	Kidney Renal Papillary Cell Carcinoma	0.0970	0.0410	2.3e-03	-0.002	0.048	0.030	NA	0.007	4.2e-01	9.9e-04	7.4e-03	NA	1.2e-01
6	TCGA	Lung Adenocarcinoma	0.0381	0.0170	2.8e-03	0.025	0.012	0.011	NA	0.008	6.3e-04	1.2e-02	1.7e-02	NA	3.1e-02
7	TCGA	Lung Squamous Cell Carcinoma	0.0531	0.0216	3.6e-04	0.006	0.031	0.025	NA	0.014	6.2e-02	1.7e-04	6.6e-04	NA	8.5e-03
8	TCGA	Pancreatic Adenocarcinoma	0.1690	0.0750	1.3e-03	0.039	0.054	0.058	NA	0.072	9.3e-03	2.7e-03	1.9e-03	NA	5.9e-04
9	TCGA	Prostate Adenocarcinoma	0.1803	0.0448	4.3e-14	0.141	0.123	0.159	NA	0.161	1.6e-14	7.6e-13	2.3e-16	NA	1.7e-16
10	TCGA	Thyroid Carcinoma	0.1410	0.0370	4.2e-10	0.114	0.087	0.141	NA	0.143	3.3e-11	7.8e-09	1.2e-13	NA	8.2e-14

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10
Birth weight	13.8	30.0	64.5	1.4	-4.0	-8.0	-7.2	-4.4	-5.7	-2.1	-6.9	-2.6	-7.4
Prostate Cancer	6.8	9.5	20.8	0.6	-4.0	-3.3	-3.1	-2.2	-4.6	-2.0	-3.5	-2.8	-3.0
Birth weight of first child	6.7	12.2	27.1	0.5	-4.1	-5.2	-3.0	-2.0	-3.4	-0.0	-5.1	-1.7	-5.0
Fasting Glucose	5.4	6.4	17.2	-1.5	3.1	1.9	1.9	1.8	2.2	1.9	4.1	1.9	3.6
Lupus	3.2	4.8	12.9	-1.6	0.4	-0.9	-1.5	-3.5	-2.3	-3.6	-0.9	-3.2	-0.8
Comparative height size at age 10	3.1	16.9	31.8	1.7	-5.3	-5.3	-4.8	-3.4	-3.9	-1.8	-5.6	-3.5	-3.7
Lung FVC	3.0	15.3	38.3	-0.9	2.5	4.7	4.7	2.9	3.8	1.7	6.2	2.9	5.4
Comparative body size at age 10	2.8	7.6	19.8	2.5	-2.3	-4.5	-3.1	-0.1	-1.7	0.7	-4.0	1.6	-3.6
Neck or shoulder pain in last month	2.8	3.9	9.7	-0.1	-2.0	-3.1	-2.4	-1.8	-2.2	-1.3	-2.1	-0.9	-2.1
Illnesses of mother	2.7	3.4	8.3	-0.6	1.2	2.3	2.6	1.7	1.7	0.7	2.9	1.2	2.0
Had menopause	2.6	3.3	10.4	0.6	-2.4	-2.2	-3.2	-1.4	-2.2	-1.0	-1.7	-0.4	-0.6
Mother’s age at death	2.5	3.2	6.0	-0.6	-1.1	-2.4	-1.9	-1.4	-2.5	-1.4	-2.3	-0.9	-2.2
Age started oral contraceptive pill	2.4	3.0	9.0	1.3	-2.0	-2.7	-3.0	-0.6	-0.9	0.8	-2.2	0.7	-1.2
Basal cell carcinoma (self-reported)	2.4	2.8	6.0	-0.0	2.0	1.0	2.5	1.6	2.2	0.8	1.7	2.4	0.4
Medication: Co-codamol	2.2	2.6	6.0	2.5	-0.8	0.6	1.1	2.0	1.6	1.6	0.1	2.1	1.9
Medication: Ibuprofen (e.g. Nurofen)	2.2	2.8	6.0	-0.4	1.7	2.5	2.4	1.4	1.6	1.3	2.2	0.7	1.0
Medication: Laxatives (e.g. Dulcolax, Senokot)	2.2	2.6	8.6	1.2	0.9	1.2	1.2	1.8	2.9	2.2	0.5	1.0	1.8
Medication: Ibuprofen	2.1	2.6	6.4	-0.7	2.0	2.5	2.1	0.8	1.5	0.8	2.5	0.5	0.4
Illnesses of siblings	2.0	2.8	6.8	-0.7	2.2	2.4	2.6	0.8	2.2	0.9	1.9	0.4	0.6
Exposure to tobacco smoke at home	2.0	2.3	8.3	0.6	1.2	1.5	1.5	1.8	2.9	1.1	0.8	1.4	1.1
Supplements: Glucosamine	1.9	2.5	5.2	-0.2	-0.4	-1.7	-2.3	-2.3	-1.5	-1.2	-1.6	-0.9	-2.1
Number of live births	1.9	2.7	11.3	0.8	-3.4	-1.8	-1.3	-0.9	-2.0	-0.3	-1.6	-1.3	-1.1
Pulse wave Arterial Stiffness index	1.9	2.3	6.8	2.1	-1.2	-1.7	-2.6	-1.4	-1.4	-1.2	-1.0	-0.6	-0.5
Eye problems/disorders: None of the above	1.9	2.2	6.8	-1.3	1.8	1.6	1.6	-0.3	1.5	-0.4	2.6	0.7	1.6
Eye problems/disorders: Diabetes related eye disease	1.8	2.0	10.9	3.3	-1.2	-0.7	-1.6	0.9	0.3	0.9	-0.8	1.4	-0.4
Pulse wave peak to peak time	1.8	2.1	6.2	-2.0	1.0	1.7	2.5	1.4	1.4	1.4	0.9	0.4	0.7
Intelligence (Savage-Jansen 2018)	1.7	5.2	9.7	0.4	1.9	2.3	2.6	3.1	2.8	3.1	2.0	1.3	1.9
Average weekly spirits intake	1.7	2.1	6.1	0.7	-2.5	-0.7	-0.9	-1.8	-1.9	-1.9	-0.7	-1.2	-0.5
Diverticular disease/diverticulitis (self-reported)	1.7	2.0	3.8	0.9	-1.9	-1.0	-1.9	-1.5	-1.8	-1.3	-1.2	-1.0	-1.1
Fluid intelligence score	1.7	3.5	8.5	1.3	0.5	1.7	1.8	2.8	2.3	2.9	1.4	1.7	0.9
Family relationship satisfaction	1.7	2.1	4.3	0.7	2.0	0.9	1.1	1.8	1.8	1.7	0.4	0.4	2.1
Average weekly beer plus cider intake	1.7	2.5	6.9	0.2	1.1	2.6	2.1	1.5	1.7	0.7	1.3	1.3	1.9
Mouth/teeth dental problems	1.5	2.3	8.3	1.0	-0.1	0.3	0.7	2.2	1.2	2.9	0.9	2.4	0.2
Medication: Seretide 50 evohaler	1.5	1.7	3.0	-0.7	1.7	1.5	1.5	1.0	1.7	0.8	1.2	1.2	1.4
Wears glasses or contact lenses	1.5	1.8	4.9	-0.0	-2.0	-2.2	-1.6	-1.0	-1.3	-1.2	-1.3	-0.6	-0.3
Eye problems/disorders: Glaucoma	1.5	1.8	4.4	1.8	-1.1	-2.0	-1.6	0.1	-1.1	0.5	-2.1	0.1	-1.3
Coronary Artery Disease (CAD)	1.4	1.7	4.8	0.9	-0.9	-1.1	-1.7	-1.0	-1.3	-1.2	-1.5	-0.0	-2.2
Diabetes (mother)	1.4	1.8	5.5	2.3	-1.4	-1.9	-1.4	-0.3	-1.2	0.3	-1.4	-0.3	-1.1
Number of incorrect matches in round	1.4	2.3	4.8	0.9	-1.0	-1.7	-1.6	-1.3	-1.9	-1.4	-2.2	-1.3	-1.6
Heel bone mineral density (BMD) T-score, automated (right)	1.4	3.2	7.0	0.8	2.6	1.1	1.7	1.6	2.5	1.4	1.9	2.4	0.8
Forced expiratory volume in 1-second (FEV1), Best measure	1.4	4.5	10.1	-0.1	0.9	2.3	2.7	2.3	2.3	2.1	2.3	0.7	3.2
Eye problems/disorders: Cataract	1.4	1.6	3.5	1.1	-1.8	-0.2	-1.2	-0.5	-1.6	-0.5	-1.5	-1.9	-1.0
Heel bone mineral density (BMD) T-score, automated (left)	1.3	3.0	6.2	1.4	1.6	1.2	1.9	1.9	2.4	1.5	1.4	2.5	0.6
Alcohol intake versus 10 years previously	1.3	2.0	6.2	-1.1	0.2	2.2	1.9	0.3	0.8	0.4	2.5	0.7	1.7
Ever highly irritable/argumentative for 2 days	1.3	1.5	6.0	-1.5	1.2	1.8	0.9	0.2	0.5	-0.0	2.4	-0.2	1.0
Qualifications: NVQ or HND or HNC or equivalent	1.3	1.5	4.8	-0.4	2.2	1.6	1.0	0.9	1.7	0.5	1.2	1.0	0.4
Financial situation satisfaction	1.3	1.6	4.9	-1.7	0.8	1.4	1.8	-0.2	0.6	-0.9	0.9	-0.9	2.2
Age when periods started (menarche)	1.2	3.0	10.7	0.5	3.3	1.4	1.1	1.2	2.3	1.4	1.1	0.4	2.3
Pain all over the body in last month	1.2	1.3	3.0	1.5	0.1	1.5	-0.1	0.7	1.6	1.0	1.0	0.4	1.7
Forced vital capacity (FVC), Best measure	1.2	4.3	11.8	-0.1	0.4	2.6	2.8	1.9	2.1	1.6	2.5	0.3	3.4
Migraine (self-reported)	1.2	1.4	4.7	-1.3	-0.5	0.8	2.2	0.6	0.7	0.8	1.4	1.0	1.6
Illnesses of father: Heart disease	1.2	1.6	5.4	1.8	-0.0	-1.0	-0.6	1.4	0.4	2.3	-0.7	1.7	-0.3
Illnesses of father: None of the above (group 1)	1.2	1.5	3.9	-1.0	-0.4	1.4	1.4	-0.0	0.3	-1.2	1.8	-0.9	2.0
Illnesses of father: High blood pressure	1.2	1.5	2.7	-0.4	0.1	-0.7	-1.3	-1.6	-1.6	-1.1	-1.3	-1.3	-1.6
Ovarian Cancer	1.1	1.4	3.3	1.1	-1.4	-1.3	-1.6	-1.1	-0.3	-0.1	-1.4	-1.8	0.4
Frequency of tenseness / restlessness in last 2 weeks	1.1	1.7	6.0	-1.1	0.4	-1.1	-0.6	-1.7	-1.9	-2.5	-0.5	-1.1	-0.6
Forced expiratory volume in 1-second (FEV1)	1.1	3.6	9.4	0.2	0.6	1.9	2.0	1.9	2.2	1.9	2.3	1.2	3.1
Lung cancer (father)	1.1	1.3	3.5	-0.6	-1.2	-0.3	-0.1	-0.9	-0.8	-1.5	-1.3	-1.4	-1.9
Glaucoma (self-reported)	1.1	1.3	4.0	2.0	-0.4	-1.6	-1.7	-0.3	-1.2	-0.1	-1.4	-0.1	-0.8
Mouth/teeth dental problems: Loose teeth	1.1	1.3	3.9	-2.0	0.8	1.8	1.4	-0.2	0.2	-0.6	1.0	-1.4	0.3
Heart disease (mother)	1.1	1.3	3.2	-0.4	-0.1	-1.2	-0.7	-1.6	-1.1	-0.7	-1.8	-1.6	-1.1
Illnesses of siblings: Diabetes	1.1	1.4	4.4	1.6	-0.8	-1.7	-2.1	-0.7	-0.7	-0.4	-1.3	0.3	0.2
Tinnitus: Yes, now most or all of the time	1.1	1.3	4.8	-0.3	2.2	0.2	-0.2	-0.1	1.1	0.6	1.8	1.6	-0.1
Ever had prostate specific antigen (PSA) test	1.1	1.2	3.8	0.4	-0.2	-1.5	-1.0	-0.9	-1.9	-1.0	-0.3	-1.5	-1.1
Triglycerides	1.0	1.7	4.9	-0.9	1.4	1.3	0.9	1.3	0.8	0.7	2.2	1.4	1.5
Serious illness, injury or assault to yourself	1.0	1.3	3.5	-1.9	0.1	0.9	1.9	0.0	-1.0	-1.5	0.6	-1.0	-0.3
Frequency of tiredness / lethargy in last 2 weeks	1.0	1.7	4.8	0.8	-1.7	-0.9	-1.5	-2.2	-1.4	-1.6	-0.7	-0.5	-0.3
Number of full sisters	1.0	1.2	3.4	0.0	-0.5	-1.0	-0.8	-1.3	-1.0	-1.1	-1.4	-1.8	-0.8
Supplements: Vitamin C	1.0	1.2	3.5	0.6	-0.6	-1.9	-1.6	-0.5	-0.5	0.3	-1.6	0.0	-1.3
Hypertension (Self-reported)	1.0	2.7	6.6	0.1	2.6	1.5	2.4	1.8	1.2	0.7	1.8	0.3	1.9
Ever had stillbirth, spontaneous miscarriage or termination	1.0	1.1	3.1	-1.5	1.8	0.8	0.6	0.5	0.8	1.2	1.3	-0.0	-0.0
Supplements: Fish oil (including cod liver oil)	1.0	1.3	4.1	1.7	0.8	-1.2	-2.0	-0.1	0.1	1.0	-0.6	1.4	-0.4
Medication: Lisinopril	1.0	1.3	3.1	0.6	0.8	0.7	1.3	1.1	1.0	-0.5	1.1	1.6	1.8
Alcohol drinker status: Never	1.0	1.1	3.7	1.4	-0.4	-1.3	-0.7	1.9	0.1	1.3	-0.8	0.9	-0.4
Heart disease (siblings)	1.0	1.2	3.0	0.8	-1.7	-0.7	-1.3	-1.5	-1.1	-1.1	-1.1	-0.5	-0.5
Alzheimer’s Disease (in mother)	0.9	1.1	2.2	-1.5	1.4	0.3	0.8	0.5	0.8	-0.9	1.4	1.5	0.2
Alzheimer’s Disease (including proxy)	0.9	1.3	3.6	-0.3	1.9	-0.9	0.1	1.1	1.4	0.9	0.4	1.9	1.0
Verbal and Numeric Reasoning (VNR)	0.9	2.1	6.0	0.7	-0.5	1.3	1.5	2.4	1.5	2.3	1.1	1.3	0.4
Blood Platelet Count	0.9	10.3	34.6	-3.7	2.2	3.8	3.7	1.6	1.5	-0.2	4.1	0.1	5.9
Blood Red Count	0.9	8.3	15.6	2.2	-3.2	-2.0	-3.5	-2.0	-3.0	-2.3	-3.3	-4.0	-2.5
Blood White Count	0.9	6.7	17.9	-1.7	2.9	4.2	3.7	1.1	1.4	-0.9	3.1	-0.8	3.1
Taking other prescription medications	0.9	1.4	3.3	0.7	-0.3	0.7	0.9	1.8	1.4	1.6	0.9	1.5	1.2
High blood pressure	0.9	2.4	6.2	-0.3	2.5	1.2	2.3	1.6	1.2	0.8	1.8	0.5	1.8
Chronic bronchitis/emphysema (father)	0.9	1.1	2.7	0.2	-0.5	-0.8	-1.6	-1.6	-1.0	-1.1	-0.8	-0.5	-1.3
Forced vital capacity (FVC)	0.9	3.3	12.3	0.7	-0.2	1.8	1.7	1.5	1.8	1.6	2.2	1.1	3.5
Noisy workplace	0.9	1.1	2.9	-0.2	1.1	0.7	0.4	1.4	1.4	1.1	0.9	1.7	0.7
Tense / ‘highly strung’	0.9	1.5	5.5	-0.5	0.2	-2.3	-1.4	-1.2	-1.8	-0.5	-1.0	-0.5	-1.1
Pulse wave reflection index	0.9	1.1	5.7	2.4	0.7	-0.6	-1.2	-0.7	-0.2	-1.2	-0.2	0.9	-0.7
Number of full brothers	0.9	1.2	3.6	1.9	0.5	1.6	1.3	0.3	1.0	-0.9	0.9	0.9	0.3
Commuting to job workplace: Car/motor vehicle	0.9	1.0	1.9	-1.1	-0.0	0.6	1.1	1.3	0.8	1.0	0.9	1.4	0.9
Ever had bowel cancer screening	0.9	1.0	2.9	-0.2	-0.0	-0.9	-1.5	-1.3	-1.7	-1.1	-0.5	-0.9	-0.2
Friendships satisfaction	0.9	1.1	3.5	-0.9	1.2	1.0	1.2	0.7	0.9	0.3	1.1	0.0	1.9
Hearing aid user	0.9	1.0	5.0	0.2	-0.0	-1.1	-1.0	1.5	0.4	2.2	-0.8	-0.0	-0.3
High cholesterol (Self-reported)	0.9	1.5	5.0	-0.2	-1.1	-0.6	0.4	-2.2	-1.3	-1.8	-0.2	-1.6	0.8
Depressed Affect (Nagel 2018)	0.8	1.6	4.3	-1.1	-1.5	-0.4	0.0	-1.4	-1.5	-1.8	-0.9	-2.1	-0.2
Neuroticism (Nagel 2018)	0.8	1.8	5.1	-1.3	-0.5	-0.7	-0.4	-1.8	-1.7	-1.5	-0.8	-2.3	-1.1
Alzheimer’s Disease (in father)	0.8	0.9	2.1	0.4	1.2	-1.4	-0.5	0.7	0.7	1.3	-0.8	0.9	0.9
Major Depression (MDD)	0.8	1.0	2.8	1.7	0.5	-1.2	-0.5	0.8	0.8	0.8	-0.9	1.2	-1.1
HbA1C	0.8	0.9	4.1	-2.0	0.2	-1.6	-0.0	-0.4	-1.1	0.3	-0.0	0.4	-1.0
Ever unenthusiastic/disinterested for a whole week	0.8	0.9	3.4	-1.8	0.6	0.7	1.1	-0.1	0.5	-0.8	1.1	-0.4	1.2
Diabetes (self-reported)	0.8	1.2	5.2	1.9	-2.3	-0.0	-0.2	0.4	0.1	-0.1	-0.7	0.9	-1.2
Happiness	0.8	1.0	3.4	-0.2	-0.8	0.6	1.2	1.8	0.6	1.1	-0.1	0.4	1.6
Age at last live birth	0.8	1.1	2.9	-1.6	-0.0	1.7	1.4	0.0	0.1	-0.0	1.3	-0.8	1.0
Illness, injury, bereavement, stress in last 2 years	0.8	1.0	3.0	0.4	-0.7	-1.2	-1.7	-0.4	-0.9	0.1	-1.2	-1.3	-0.5
Smoking status: Previous	0.8	1.2	2.9	0.9	0.4	1.1	0.7	1.3	1.7	1.4	0.4	1.4	0.1
Handedness (chirality/laterality): Left-handed	0.8	1.0	4.7	0.2	0.8	-0.1	0.0	1.4	0.4	1.4	0.6	2.2	0.2
Diabetes diagnosed by doctor	0.8	1.3	4.7	2.2	-1.8	-0.9	-0.5	0.5	-0.0	0.3	-1.0	1.3	-1.3
Medication: Gliclazide	0.8	0.9	4.7	0.4	-2.2	-0.4	0.2	-0.6	-1.1	-1.4	0.0	0.3	-0.1
Average weekly champagne plus white wine intake	0.8	1.1	3.1	0.9	1.6	-1.1	-0.4	0.5	0.6	1.5	0.4	1.8	0.2
Bipolar Disorder (2018)	0.7	1.1	3.1	0.2	0.7	-0.8	-1.1	-1.8	-1.1	-1.4	-1.0	-1.3	-0.3
Depression (Nagel 2018)	0.7	1.0	2.4	-1.5	-0.1	-0.8	-0.1	-1.2	-1.3	-1.1	-0.9	-1.1	-0.7
Schizophrenia vs Biploar Disorder	0.7	1.0	3.6	-0.5	-0.1	-1.3	-1.4	-1.1	-0.8	0.1	0.0	-0.3	-1.9
Worry (Nagel 2018)	0.7	1.5	3.2	-1.2	-0.4	-1.8	-1.1	-1.3	-1.7	-0.3	-1.1	-1.6	-0.7
Type 2 Diabetes (T2D) (2018)	0.7	1.3	6.9	2.6	-0.8	0.3	0.7	0.7	1.2	0.4	-0.1	1.7	-0.7
Sensitivity / hurt feelings	0.7	1.2	3.9	-0.6	2.0	0.8	1.0	-0.3	1.0	-0.1	2.0	-0.0	1.1
Ever used hormone-replacement therapy (HRT)	0.7	0.9	2.0	1.1	-0.5	-0.3	-1.2	-0.7	-1.3	-1.3	-0.2	-0.3	-1.4
Financial difficulties in last 2 years	0.7	1.0	2.3	-0.2	-0.4	1.0	1.5	-0.7	1.0	-1.0	0.5	1.2	1.4
Heart attack	0.7	0.9	2.4	0.0	-1.5	-0.2	-1.0	-1.3	-0.8	-1.4	-0.4	-1.1	-0.5
Medication: Ramipril	0.7	1.0	2.6	-0.5	1.6	0.7	1.3	0.7	0.8	0.6	0.9	0.2	1.4
Father’s age at death	0.7	0.9	2.1	0.8	1.3	-0.2	-1.3	1.4	0.4	1.1	-0.4	0.5	1.0
Prospective memory result	0.7	0.9	3.0	-0.5	1.7	-0.9	-1.0	0.2	1.1	0.6	0.6	1.2	0.8
Length of working week for main job	0.7	0.8	2.1	1.1	-1.2	-0.5	-0.3	-1.4	-0.4	-1.1	-0.9	-0.0	-0.8
Breastfed as a baby	0.7	0.9	2.6	0.9	-0.3	-0.3	-0.6	-1.3	-0.9	-1.6	-0.3	-1.4	0.5
Mouth/teeth dental problems: Bleeding gums	0.7	0.9	2.0	-0.5	0.3	-0.8	-0.6	-1.1	-0.2	-1.2	-0.9	-1.3	-1.4
Wheeze or whistling in the chest in last year	0.7	1.3	5.7	2.4	0.5	-1.6	-1.1	-0.2	0.6	-0.1	-0.5	1.5	-0.5
Medication: Blood pressure	0.7	1.2	3.8	1.4	0.4	1.0	1.7	0.6	1.1	-0.2	0.1	0.6	1.9
Mean time to correctly identify matches	0.7	1.4	5.6	0.7	0.2	-2.4	-2.0	0.7	-0.4	1.5	-0.6	0.6	0.3
Alcohol intake frequency.	0.7	1.5	3.7	0.1	-1.4	-1.0	-0.3	1.7	0.7	1.8	-0.1	1.9	1.4
Had major operations	0.7	0.9	2.9	0.1	-1.4	1.3	0.4	0.8	-0.5	0.6	-0.4	-1.7	-0.7
Loneliness, isolation	0.7	0.9	3.9	-1.0	-0.2	-0.5	0.7	-0.4	-1.1	-2.0	-0.3	-1.4	-0.1
Qualifications: nursing, teaching	0.7	1.1	2.4	-1.5	-0.5	-1.2	-0.9	-1.3	-0.9	-0.5	-0.9	-0.9	-1.2
Mouth/teeth dental problems: Mouth ulcers	0.7	1.1	2.0	0.0	-0.7	-0.7	-1.4	-1.4	-1.0	-1.0	-1.4	-1.4	-0.6
Back pain experienced in last month	0.7	1.0	3.7	-0.7	-0.6	1.4	1.9	1.0	0.5	-0.4	1.0	1.0	0.1
Osteoporosis (self-reported)	0.7	0.9	2.8	0.8	-0.2	-0.2	-1.6	0.6	0.5	1.7	-0.4	0.9	1.0
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.7	1.6	4.7	-1.1	0.0	1.5	1.4	0.7	1.1	1.3	1.5	-0.5	2.2
Medication: Blood pressure	0.7	1.3	3.7	0.0	1.1	0.4	1.3	1.9	0.8	0.9	0.9	1.0	1.5
Risk taking	0.7	1.0	2.5	0.7	1.5	0.8	0.5	-1.4	0.7	-1.6	0.6	-0.2	1.0
Vascular/heart problems diagnosed by doctor	0.7	2.0	4.4	0.4	-1.9	-1.1	-2.0	-1.2	-1.2	-0.4	-1.8	-0.5	-2.1
Supplements: Calcium	0.7	0.7	2.9	0.6	-0.5	-1.2	-1.7	-0.2	-0.1	0.6	-1.2	0.1	-0.8
Alcohol drinker status: Previous	0.7	0.8	2.0	0.5	-1.0	1.1	0.4	1.4	1.0	1.2	0.4	0.7	0.7
Systolic Blood Pressure	0.6	2.9	9.9	-3.1	1.9	1.6	1.7	0.2	0.1	-1.1	2.1	-1.0	1.9
Chronotype (morning person)	0.6	1.4	5.2	1.3	-0.0	-1.7	-1.3	-0.0	-0.1	1.0	-2.3	-0.3	-1.4
Other serious medical condition/disability diagnosed by doctor	0.6	0.8	1.3	0.8	-0.6	1.1	0.9	0.9	1.1	0.9	-0.9	0.3	1.1
Medication: Metformin	0.6	0.9	4.4	1.1	-2.1	-0.5	0.2	0.4	-0.5	-0.4	-0.1	1.6	-0.2
Diabetes (father)	0.6	0.7	3.5	-0.3	0.3	-0.9	-1.0	-0.4	-0.5	-0.8	-0.4	0.4	-1.9
Severe depression (siblings)	0.6	0.6	3.7	-0.4	-0.2	0.1	-0.4	-0.9	-0.7	-0.7	-0.8	-1.9	0.1
Pack years adult smoking proportion	0.6	0.8	2.8	-0.6	-0.1	1.1	1.7	1.2	0.1	-0.6	1.4	0.3	0.5
Bilateral oophorectomy (both ovaries removed)	0.6	0.7	3.1	0.6	0.5	-1.0	-1.8	0.0	-1.3	0.7	-0.5	0.2	-0.5
High blood pressure (mother)	0.6	0.8	2.6	0.9	-1.0	-0.6	-0.9	-0.1	-0.9	0.0	-1.6	-1.1	-0.6
Medication: Cholesterol lowering	0.6	0.9	2.4	0.9	-1.5	-1.2	0.2	-0.8	-0.8	-1.1	-1.1	0.7	-0.8
Peak expiratory flow (PEF)	0.6	1.4	3.9	0.3	-0.7	2.0	1.5	1.5	1.0	1.0	1.2	0.2	1.0
Medication for cholesterol, blood pressure or diabetes	0.6	1.0	3.1	-1.7	0.4	-0.4	-1.8	-0.6	-0.9	0.3	0.2	-1.1	-1.0
Hypothyroidism/myxoedema (self-reported)	0.6	1.1	2.7	-0.1	-0.1	1.2	0.6	0.8	1.6	0.7	1.5	1.5	1.0
Medication: Aspirin	0.6	0.8	2.2	1.5	-1.3	-1.3	-1.0	-0.1	-0.2	0.0	-1.1	0.4	0.6
Knee pain experienced in last month	0.6	0.9	3.8	1.5	-0.1	0.3	0.0	1.0	0.8	0.1	0.6	2.0	1.0
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.6	0.7	2.1	0.9	1.0	1.3	0.7	0.8	1.4	0.5	0.5	0.4	-0.2
Medication: Aspirin	0.6	0.7	2.7	1.0	-1.6	-1.1	-0.9	-0.5	-0.7	-0.4	-0.8	-0.0	0.5
Smoking status: Current	0.6	1.0	3.3	-0.9	0.9	-0.0	-0.0	-1.4	-0.4	-1.8	1.2	0.1	1.2
Number of self-reported non-cancer illnesses	0.6	1.1	2.6	0.6	1.6	1.4	1.2	0.8	1.1	0.5	1.4	0.5	0.7
Commuting to job workplace: Public transport	0.6	0.7	1.7	-0.3	-0.7	-0.5	-0.3	-1.2	-1.1	-0.8	-0.5	-1.3	-1.0
Fractured/broken bones in last 5 years	0.6	0.8	2.0	0.9	-1.4	-0.0	-0.5	0.8	-0.7	0.9	-1.3	-0.5	-1.0
Cholesterol lowering medication	0.6	0.8	2.1	0.1	-0.6	-0.7	-0.7	-1.3	-1.2	-1.5	-0.2	-1.2	0.1
Reaction Time	0.5	1.0	4.6	0.3	-0.2	-2.1	-1.2	1.0	-0.1	1.5	-0.7	0.5	0.5
Body Mass Index (BMI) (2010)	0.5	0.7	2.9	-1.7	0.2	0.1	0.9	0.8	-0.9	-0.5	-0.2	-1.0	-0.3
Hand grip strength (left)	0.5	1.4	3.0	-0.8	1.2	1.7	1.5	0.7	1.6	0.4	1.2	1.4	0.3
Frequency of depressed mood in last 2 weeks	0.5	0.7	2.0	-0.1	0.3	-1.1	-0.3	-0.8	-1.3	-1.4	-1.1	-0.5	-0.4
Supplements: Zinc	0.5	0.6	3.4	0.3	0.2	-1.0	-0.8	0.3	-0.1	0.1	-1.8	-0.3	-0.5
Hand grip strength (right)	0.5	1.3	2.8	-1.6	1.5	1.7	1.6	0.1	1.3	-0.1	1.2	0.3	-0.2
Current tobacco smoking	0.5	0.9	3.5	-0.6	0.4	-0.4	-0.4	-1.6	-0.8	-1.9	0.8	-0.2	0.8
Stomach or abdominal pain in last month	0.5	0.7	2.7	-1.6	-0.0	0.6	1.3	-0.1	-0.2	-1.1	0.6	-0.4	-0.3
Medication: Levothyroxine sodium	0.5	0.8	3.0	0.2	-0.3	0.2	0.0	1.1	0.9	0.9	1.0	1.7	0.8
Past tobacco smoking	0.5	0.9	2.3	-0.6	-0.5	-0.8	-0.6	-1.2	-1.5	-1.3	-0.2	-1.4	-0.1
Qualifications: A levels/AS levels or equivalent	0.5	1.0	2.4	0.0	0.8	1.1	1.6	1.1	1.5	1.0	0.4	0.1	-1.1
Mouth/teeth dental problems: Dentures	0.5	0.9	3.2	-0.3	0.0	0.6	0.1	-0.8	-0.6	-1.6	0.0	-1.2	1.8
Impedance of arm (left)	0.5	2.2	6.7	-1.1	1.4	1.8	0.6	-1.7	-0.2	-1.4	1.2	-2.6	1.3
Hair/balding pattern: Pattern 4	0.5	1.1	3.3	0.8	-1.8	-1.4	-1.6	-0.6	-0.7	-0.2	-0.7	0.7	-0.9
Blood clot in the leg (DVT)	0.5	0.7	2.2	0.2	0.9	0.4	-0.4	-1.0	-0.9	-1.2	-0.2	-1.5	0.4
Chronic bronchitis/emphysema (mother)	0.5	0.6	1.5	0.7	0.3	-0.8	-1.1	0.1	0.3	1.2	-1.1	0.5	-0.6
High blood pressure (siblings)	0.5	0.7	2.4	0.6	-0.8	-1.5	-1.5	0.4	-1.0	0.4	-0.5	0.0	0.1
Seen a psychiatrist for nerves, anxiety, tension or depression	0.5	0.7	2.5	-1.6	-1.3	0.1	0.8	-0.6	-0.8	-0.4	-0.4	-0.9	-0.1
Pulse rate, automated reading	0.5	1.6	5.7	0.4	-1.3	-0.7	-0.6	-0.8	-1.4	-0.9	-0.8	-2.4	1.8
Leg pain on walking	0.5	0.7	3.6	1.9	-0.3	-0.1	-0.5	0.2	0.7	0.4	0.7	1.2	0.3
Mood swings	0.5	0.9	2.7	0.5	-1.5	0.2	-0.2	-0.9	-0.9	-1.6	-0.0	-1.3	0.6
Breast cancer (self-reported)	0.5	0.6	2.0	-1.4	1.4	0.1	-0.1	0.9	0.2	0.8	0.7	-0.1	0.5
Number of operations (self-reported)	0.5	0.8	2.9	0.8	-0.1	1.2	0.1	1.7	0.9	0.9	0.7	0.7	0.5
Heart attack/myocardial infarction (self-reported)	0.5	0.7	2.4	0.1	-1.5	-0.1	-0.8	-1.1	-0.4	-1.1	-0.3	-0.9	-0.4
Deep venous thrombosis (DVT) (self-reported)	0.5	0.6	1.7	0.3	1.0	0.3	-0.5	-0.9	-0.8	-1.3	-0.2	-1.2	0.2
Pack years of smoking	0.5	0.8	2.2	-0.7	0.3	0.9	1.3	1.2	0.2	-0.2	1.5	0.4	0.7
Arm predicted mass (left)	0.5	2.3	5.8	2.0	-2.3	-2.4	-1.5	0.7	-0.5	1.0	-1.4	1.2	-0.7
Bipolar Disorder or Schizophrenia	0.4	1.0	2.6	0.5	1.6	-1.5	-1.2	-1.0	-0.7	-0.5	-0.8	0.2	-1.1
Schizophrenia (2018)	0.4	0.8	2.6	0.4	1.6	-1.3	-0.7	0.1	-0.0	0.5	-0.3	1.3	-1.1
Crohns Disease (2012)	0.4	0.7	2.4	0.5	-0.6	0.4	0.4	-0.3	-1.1	-1.3	-0.1	-1.6	0.8
Mean Putamen Volume	0.4	0.4	1.4	-0.1	-1.2	0.1	-0.5	-0.4	-1.0	-0.3	-0.5	-1.0	-0.4
Rheumatoid Arthritis	0.4	0.5	1.3	1.2	-0.5	0.6	0.5	-0.2	-0.4	-1.1	-0.8	-0.8	0.2
Ulcerative Colitis	0.4	0.6	1.7	-1.3	0.4	-0.5	-0.2	-0.5	-0.9	-0.7	-0.5	-1.2	-0.6
Lung FEV1/FVC ratio	0.4	2.1	6.9	1.6	0.7	0.3	0.7	2.4	1.6	2.6	-0.2	1.1	0.9
Hearing difficulty/problems: Yes	0.4	0.6	1.8	0.4	0.8	-0.7	-0.6	0.7	0.9	1.3	-0.2	1.3	-0.1
Relative age of first facial hair	0.4	0.9	2.7	-1.6	0.2	1.6	0.8	-0.4	0.1	-0.9	1.0	-1.0	0.6
Medication for hormone replacement therapy	0.4	0.4	2.1	-0.2	0.4	0.4	0.2	-0.0	-0.5	-0.8	1.5	0.7	-0.1
Impedance of leg (right)	0.4	2.1	4.7	-2.2	1.5	1.1	0.5	-1.4	-0.4	-1.7	1.7	-1.5	1.6
Average weekly fortified wine intake	0.4	0.5	1.8	1.0	0.1	-1.3	-1.1	0.1	-0.5	-0.3	0.4	0.8	0.2
Maternal smoking around birth	0.4	0.5	2.6	1.0	-0.1	0.6	-0.0	-0.7	-0.2	-1.6	-0.5	-0.2	0.7
Relative age voice broke	0.4	0.6	1.8	-1.1	1.1	0.9	1.3	0.3	0.8	-0.1	0.0	-0.1	-0.1
Qualifications: CSEs or equivalent	0.4	0.6	4.0	-2.0	0.5	0.7	0.6	-0.2	0.4	-0.3	0.3	0.6	-0.4
Impedance of leg (left)	0.4	2.1	4.9	-1.9	2.1	1.2	0.6	-1.3	0.1	-1.5	2.2	-0.7	1.4
Hearing difficulty/problems with background noise	0.4	0.6	2.2	-1.0	-0.2	-1.5	-1.1	-0.5	-0.5	-0.1	-0.8	0.5	-0.8
Trunk fat-free mass	0.4	2.3	5.5	2.3	-2.1	-2.1	-1.2	1.4	-0.1	1.5	-1.1	1.3	-0.1
Falls in the last year	0.4	0.6	2.1	-0.6	0.9	0.7	0.5	-0.1	-0.6	-0.8	0.4	-0.8	1.5
Pulse rate	0.4	0.6	2.7	-0.5	-1.2	-0.4	-0.1	0.5	-0.8	0.2	-0.8	-1.6	0.5
Asthma	0.4	0.7	1.4	0.8	1.1	-0.9	-1.1	0.3	0.4	0.1	0.8	1.2	-1.0
Trunk predicted mass	0.4	2.3	5.8	2.4	-2.1	-2.1	-1.2	1.4	-0.2	1.5	-1.1	1.3	-0.2
Medication: Amlodipine	0.4	0.5	1.2	-0.3	1.1	0.5	1.1	0.7	0.8	0.3	0.4	1.1	0.4
Worry too long after embarrassment	0.4	0.7	3.3	-0.9	1.8	0.1	0.1	-0.8	1.0	0.3	0.5	-0.0	-0.8
Number of children fathered	0.4	0.4	1.8	0.1	1.3	0.3	0.5	0.1	0.1	-0.1	1.3	0.6	-0.5
Arm predicted mass (right)	0.4	1.8	4.2	1.9	-2.0	-1.9	-0.9	1.2	-0.0	1.3	-1.1	1.4	-0.2
Chest pain or discomfort	0.4	0.6	2.4	-0.0	0.4	-0.8	0.1	0.5	0.7	0.8	0.3	1.3	-1.6
Medication for cholesterol	0.4	0.6	2.0	0.1	-0.7	-0.6	-0.9	-1.0	-0.1	-0.3	-1.4	-0.7	-1.0
Mineral and other dietary supplements	0.4	0.6	2.4	-1.2	-0.2	0.6	1.5	0.7	-0.1	-0.3	0.4	-0.8	0.3
Asthma (self-reported)	0.4	0.8	1.5	1.0	1.0	-1.0	-1.0	0.3	0.5	0.2	0.5	1.2	-1.2
Osteoarthritis (self-reported)	0.4	0.5	1.3	0.2	0.1	-0.5	-1.1	-0.4	-1.1	-0.4	0.7	-1.0	0.6
Miserableness	0.4	0.6	2.3	0.1	-1.5	0.8	1.0	-0.3	-0.4	-1.3	0.3	-0.4	0.6
Pain type(s) experienced in last month: Hip pain	0.4	0.5	1.6	-0.6	-0.2	-0.9	-1.2	-1.0	-0.5	-0.2	0.8	-0.4	0.1
Arm fat-free mass (left)	0.4	2.3	5.7	1.9	-2.4	-2.4	-1.4	1.0	-0.5	1.1	-1.3	1.2	-0.7
Myopia	0.4	0.6	1.4	0.9	1.2	1.0	0.6	0.4	1.0	0.2	0.8	0.4	-0.2
Impedance of whole body	0.4	2.0	3.5	-1.6	1.9	1.5	0.6	-1.5	-0.1	-1.4	1.5	-1.9	1.1
Crohns Disease (2017)	0.3	0.7	3.0	0.7	-0.6	-0.3	-0.9	-1.1	-0.7	-0.5	-0.2	-1.7	0.6
Irritable Bowel Disease (IBD)	0.3	0.6	2.6	-1.1	0.2	-0.0	0.1	-1.0	-0.7	-0.7	0.3	-1.6	-0.0
Ulcerative Colitis (UC)	0.3	0.5	2.2	-1.5	0.6	0.0	0.8	-0.3	-0.6	-0.8	0.2	-0.8	-0.3
Breast Cancer	0.3	0.8	2.5	0.3	0.9	1.2	1.6	0.7	0.7	0.8	0.8	0.9	-0.4
Age at First Birth	0.3	0.5	1.2	0.2	-1.0	-0.3	0.0	-1.0	-0.5	-0.6	-1.1	-0.7	-0.7
HDL Cholesterol	0.3	0.4	1.5	-0.8	-0.2	-0.5	-0.0	-1.1	-0.4	-0.4	-0.0	-1.2	-0.4
LDL Cholesterol	0.3	0.5	1.8	-1.3	0.8	0.2	-0.2	0.1	0.6	0.6	0.9	-0.1	0.9
Neuroticism (2016)	0.3	0.4	1.2	0.4	-1.1	-0.1	0.4	0.1	-0.5	-0.3	-0.7	-0.6	0.9
Schizophrenia (2014)	0.3	0.7	2.5	0.3	1.5	-1.6	-1.2	-0.2	-0.6	0.3	-0.1	0.6	-0.4
Blood Eosinophil Count	0.3	2.7	8.6	2.9	0.5	0.3	-0.3	1.4	2.2	2.0	-1.5	1.6	1.3
Cardiovascular Disease	0.3	0.9	2.4	-0.6	1.6	1.1	1.5	0.2	0.1	-0.4	1.2	-0.5	1.0
Hypothyroidism (self reported)	0.3	0.6	2.0	-0.2	-0.9	1.2	0.3	0.1	0.8	-0.1	1.4	0.5	1.0
Ever had hysterectomy (womb removed)	0.3	0.3	1.1	0.8	0.4	0.4	0.2	0.5	0.3	0.1	-0.1	0.9	-1.1
Systolic blood pressure, automated reading	0.3	0.9	4.7	-2.2	-0.2	-0.5	-0.3	-0.3	-1.4	-0.6	0.1	-1.3	-0.1
Leg fat-free mass (left)	0.3	1.4	4.2	2.0	-1.9	-1.6	-1.0	0.7	-0.4	1.0	-1.2	0.4	-0.5
Tinnitus: Yes, but not now, but have in the past	0.3	0.4	1.7	-0.7	0.4	-0.4	0.1	0.1	-0.6	-1.3	-0.6	0.4	-0.3
Medication: Atenolol	0.3	0.3	2.1	-0.1	0.4	-0.2	-0.2	-0.5	0.4	-0.1	-0.6	-0.6	1.4
Leg predicted mass (left)	0.3	1.5	4.0	2.0	-1.9	-1.6	-1.0	0.7	-0.4	1.0	-1.2	0.4	-0.5
Alcohol usually taken with meals	0.3	0.6	2.6	1.2	-0.4	-0.8	-0.4	-0.0	0.3	0.4	-1.6	0.3	-0.5
Nervous feelings	0.3	0.6	1.7	-0.3	-0.0	-1.3	-0.7	-1.0	-1.0	-1.0	-0.6	-0.1	-0.2
Hair/balding pattern: Pattern 2	0.3	0.4	1.7	0.1	0.4	0.8	0.7	-0.1	-0.9	-0.3	-0.0	-1.3	0.6
Had other major operations	0.3	0.4	1.2	0.4	-0.1	0.4	0.2	0.7	0.0	1.0	0.8	0.2	1.1
Allergy	0.3	0.6	2.7	-0.5	-0.2	0.8	0.4	0.8	-0.2	0.5	1.0	-0.4	1.6
Medication: Simvastatin	0.3	0.5	1.2	1.1	-1.0	-0.7	-0.5	-0.6	-0.4	-0.4	-1.0	0.3	-0.4
Impedance of arm (right)	0.3	1.6	4.9	-0.7	1.3	1.1	-0.0	-2.1	-0.5	-1.4	0.8	-2.2	0.8
Time employed in main current job	0.3	0.3	1.9	0.2	1.4	-0.2	-0.3	0.7	-0.5	0.7	-0.1	-0.4	-0.1
Hair/balding pattern: Pattern 3	0.3	0.5	1.6	-0.2	-0.4	0.4	0.2	0.7	1.1	1.0	-0.2	0.2	1.3
Medication: Lansoprazole	0.3	0.4	1.3	0.3	0.5	1.0	0.3	-0.1	0.1	-0.1	0.9	-0.1	1.1
Seen doctor (GP) for nerves, anxiety, tension or depression	0.3	0.5	3.2	-1.8	-0.4	0.3	0.7	-0.5	-0.4	-0.2	0.7	0.3	0.3
Qualifications: O levels/GCSEs or equivalent	0.3	0.6	1.9	-1.0	0.0	1.0	1.4	0.2	0.1	0.3	1.2	0.0	-0.3
Headache pain in last month	0.3	0.6	1.7	-1.2	-1.3	-1.0	0.1	0.1	-0.7	-0.3	-0.2	-0.2	-1.1
Gout (self-reported)	0.3	0.4	1.7	-0.2	-0.3	-0.7	-1.3	-0.1	-1.0	-0.4	-0.5	-0.7	-0.1
Medication: Ventolin 100micrograms inhaler	0.3	0.4	1.7	-0.3	-0.2	-1.3	-0.1	-0.2	-0.5	-0.6	-0.8	0.1	-0.8
Arm fat-free mass (right)	0.3	1.7	4.3	1.6	-1.9	-2.1	-0.9	1.1	-0.2	1.1	-1.1	1.3	-0.5
Exposure to tobacco smoke outside home	0.3	0.5	1.3	-1.0	0.1	0.5	0.4	1.1	0.6	1.1	0.2	0.3	0.4
Qualifications: College or University degree	0.3	1.0	3.0	1.1	-0.8	-0.6	-0.4	-0.2	-0.5	-0.8	-1.6	-0.9	-1.7
Emphysema/chronic bronchitis	0.3	0.4	1.2	-0.3	-0.5	-0.2	-0.4	0.9	0.8	0.4	-0.2	1.1	0.3
Angina (self-reported)	0.3	0.4	2.8	-0.3	-0.0	0.3	0.1	0.5	0.7	0.5	0.6	0.1	1.7
Whole body fat-free mass	0.3	2.0	4.7	2.2	-2.0	-2.0	-1.1	1.2	-0.2	1.3	-1.2	1.1	-0.4
Leg fat-free mass (right)	0.3	1.5	5.5	2.4	-1.6	-1.5	-0.8	0.9	0.1	1.2	-1.1	0.8	-0.5
Average weekly red wine intake	0.3	0.4	3.2	1.8	0.2	-0.3	-0.1	0.0	0.3	-0.5	-0.5	-0.5	-0.3
Commuting to job workplace: Walk	0.3	0.3	1.2	-0.8	-0.2	0.3	0.6	0.5	-0.0	-0.1	-0.3	-1.1	-0.6
Whole body water mass	0.3	1.9	4.7	2.2	-2.0	-1.9	-1.0	1.2	-0.1	1.4	-1.1	1.2	-0.3
Leg predicted mass (right)	0.3	1.5	5.3	2.3	-1.6	-1.5	-0.7	0.9	0.0	1.2	-1.0	0.8	-0.5
Ever taken oral contraceptive pill	0.3	0.3	1.9	0.3	-0.1	-0.3	-0.1	0.0	0.5	0.2	-0.4	0.9	-1.4
Basal metabolic rate	0.3	1.6	3.9	2.0	-1.9	-1.8	-1.0	0.9	-0.3	1.1	-1.0	0.9	-0.4
Ever depressed for a whole week	0.3	0.4	1.1	-0.8	0.5	0.1	1.0	0.7	0.3	0.6	0.3	-0.0	1.0
Commuting to job workplace: Cycle	0.3	0.4	1.1	0.2	0.3	-0.0	-0.8	-0.5	-0.5	-0.2	-1.0	-0.8	-1.1
Medication: Omeprazole (e.g. Zanprol)	0.3	0.4	1.0	-0.2	-0.1	-0.2	-0.6	-0.8	-0.3	-1.0	-0.7	-0.9	-0.6
Bipolar Disorder (2011)	0.2	0.2	1.3	-0.5	-1.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Type 2 Diabetes (T2D) (2012)	0.2	0.2	0.9	0.5	0.2	-0.3	0.0	-0.5	0.1	-0.7	-0.5	0.3	-0.9
Heel T-Score	0.2	1.9	6.5	0.6	0.1	1.6	1.4	0.3	2.1	0.8	1.2	0.1	2.5
Height	0.2	4.4	10.0	2.5	-3.2	-2.4	-2.1	-1.1	-2.0	-0.3	-2.5	-2.3	1.0
Waist Hip Ratio (WHR)	0.2	0.7	2.4	-0.1	-0.1	0.8	1.2	0.6	0.4	0.7	1.1	-0.2	1.5
Smoking Status	0.2	0.6	2.0	1.0	0.6	0.4	-0.3	-0.2	0.8	-0.5	0.7	1.4	0.9
Respiratory disease	0.2	0.4	0.8	0.8	0.4	-0.7	-0.9	0.6	0.6	0.5	-0.0	0.7	-0.8
Angina	0.2	0.3	2.4	-0.2	-0.2	0.3	0.1	0.2	0.5	0.0	0.4	-0.3	1.6
Trunk fat percentage	0.2	0.6	1.7	-0.1	-0.1	-0.6	-1.2	-1.3	-1.2	-1.0	0.3	-0.5	-0.1
Townsend deprivation index at recruitment	0.2	0.2	1.3	0.3	-0.3	0.1	-0.3	-0.5	-0.6	-1.1	-0.1	-0.3	0.1
Hayfever, allergic rhinitis or eczema	0.2	0.4	1.8	-0.0	0.2	-0.4	0.4	-0.9	0.8	-0.1	-0.9	0.3	-1.3
Sitting height	0.2	1.3	5.5	1.6	-2.4	-1.6	-0.6	0.2	-0.5	0.5	-0.8	-0.8	0.2
Hayfever/allergic rhinitis (self-reported)	0.2	0.3	1.5	0.2	0.6	0.3	0.5	-0.0	1.2	0.8	0.0	-0.6	-0.0
Weight	0.2	1.0	2.7	1.3	-1.3	-1.6	-1.2	0.6	-0.7	0.9	-0.6	0.8	-0.2
Worrier / anxious feelings	0.2	0.4	2.4	-0.7	0.5	-0.1	0.0	-0.5	-0.5	0.1	0.1	-1.5	0.9
Serious illness, injury or assault of a close relative in last 2 years	0.2	0.3	1.2	0.6	-0.6	-0.4	-0.1	0.2	0.1	0.6	-1.1	-0.2	-0.3
Depression (self-reported)	0.2	0.2	0.6	0.3	-0.4	0.2	0.8	0.4	0.6	0.6	-0.5	0.0	0.4
Standing height	0.2	2.4	6.9	2.6	-1.8	-2.2	-1.6	-0.2	-0.6	0.6	-1.7	-1.4	0.8
Medication: Paracetamol	0.2	0.3	0.9	-0.1	-0.4	0.0	-0.6	-0.1	-1.0	0.0	-0.2	-0.9	-0.6
Leg fat percentage (right)	0.2	0.6	1.6	-1.0	-0.3	-0.4	-0.7	-0.5	-1.3	-0.9	1.1	0.5	0.2
Reason for reducing amount of alcohol drunk: Health precaution	0.2	0.2	1.2	0.5	-0.0	0.5	0.2	0.5	-0.2	1.1	0.2	0.4	-0.0
Medication for pain relief, constipation, heartburn	0.2	0.4	1.0	-0.9	-0.0	-1.0	-0.4	-0.7	-0.6	-0.5	-0.6	-0.0	-0.7
Medication: Allopurinol	0.2	0.3	1.8	-0.2	-0.3	0.6	0.3	-0.0	-0.4	-0.8	0.0	-1.4	0.3
Medication: Omeprazole	0.2	0.2	0.9	-0.3	0.4	-0.1	-0.3	-0.3	0.1	-0.9	-0.5	-0.7	0.1
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.2	0.2	1.1	-1.0	0.3	0.2	-0.2	0.1	0.3	0.4	0.3	0.7	0.3
Suffer from ‘nerves’	0.2	0.4	1.5	-0.4	0.5	-0.7	-0.4	0.2	-0.1	0.7	0.7	-0.2	1.2
Overall health rating	0.2	0.4	2.2	1.0	0.5	0.1	-0.2	0.1	0.4	0.1	0.7	0.2	1.5
Forced expiratory volume in 1-second (FEV1), predicted	0.2	0.4	0.8	0.4	-0.9	0.4	0.7	-0.3	-0.6	-0.8	-0.1	-0.9	-0.6
Guilty feelings	0.2	0.3	1.9	0.2	0.2	-0.3	0.6	-0.1	0.3	0.2	-0.5	-0.4	-1.4
Medication: Paracetamol	0.2	0.3	1.3	-0.3	-0.0	0.5	-0.4	0.3	-0.6	0.4	0.1	-1.1	-0.7
Medication: Atorvastatin	0.2	0.3	0.7	-0.1	-0.3	-0.1	0.3	-0.8	-0.4	-0.8	0.9	0.2	0.8
Leg fat percentage (left)	0.2	0.6	1.9	-0.6	0.0	-0.4	-0.7	-0.4	-1.0	-0.7	1.4	1.1	0.1
Irritability	0.2	0.3	1.4	0.1	-1.1	-0.1	-0.4	0.1	-0.6	0.5	0.0	0.0	-1.2
Diastolic blood pressure, automated reading	0.2	0.5	2.2	-0.7	-0.3	-1.0	0.0	-0.2	-0.9	-0.6	-0.4	-1.5	0.1
Pain experienced in last month	0.2	0.3	1.2	0.2	0.4	0.5	0.6	0.9	0.1	1.1	-0.6	-0.4	0.1
Primary Biliary Cirrhosis	0.1	0.2	0.5	0.7	0.7	-0.1	0.1	-0.4	-0.2	-0.4	0.1	0.7	-0.1
BMI	0.1	0.7	1.6	-1.0	0.0	-1.1	-0.9	0.2	-1.0	0.4	-1.1	-0.0	-1.2
Allergy or Eczema	0.1	0.3	1.1	0.2	0.3	-0.7	0.2	-0.2	0.8	0.4	-1.1	0.6	-0.5
Neuroticism	0.1	0.3	0.6	0.3	0.6	-0.8	-0.5	-0.7	-0.4	0.2	0.4	-0.5	-0.8
Tanning	0.1	1.8	4.5	-0.3	-1.9	-1.6	-1.1	-0.9	-1.2	-0.6	-2.1	-0.7	-1.5
Number of treatments/medications taken	0.1	0.2	1.0	1.0	-0.3	-0.0	0.3	0.8	-0.1	0.4	-0.3	-0.1	0.5
Vitamin and mineral supplements	0.1	0.2	0.4	-0.5	0.3	0.6	0.7	0.1	-0.3	-0.4	0.6	-0.4	0.3
Frequency of unenthusiasm / disinterest in last 2 weeks	0.1	0.1	0.3	-0.2	0.1	-0.4	0.4	0.2	0.0	0.0	-0.1	0.0	0.5
Multivitamins +/- minerals	0.1	0.1	0.4	0.1	0.1	-0.1	-0.6	-0.4	0.2	0.4	-0.1	0.2	-0.6
Body mass index (BMI)	0.1	0.5	2.1	0.2	-0.5	-0.6	-0.6	0.7	-0.5	0.6	0.1	1.4	-0.6
Trunk fat mass	0.1	0.4	1.4	0.5	-0.6	-0.9	-1.2	-0.5	-1.0	-0.4	0.2	0.2	0.0
Waist circumference	0.1	0.4	1.3	-0.1	-0.2	0.1	0.1	0.6	0.0	0.5	1.1	0.7	1.1
Qualifications: None of the above	0.1	0.2	0.8	-0.1	0.1	-0.4	-0.4	0.4	-0.2	0.1	0.9	-0.1	0.7
Neuroticism score	0.1	0.1	0.4	0.3	0.0	-0.6	-0.2	-0.5	-0.1	0.1	0.5	-0.4	0.1
Hip circumference	0.1	0.4	0.9	0.7	-0.2	0.2	-0.3	0.9	0.0	0.8	0.9	0.8	0.8
Arm fat mass (right)	0.1	0.3	0.8	0.6	-0.7	-0.7	-0.9	-0.0	-0.6	0.2	0.0	0.7	-0.1
Loud music exposure frequency	0.1	0.1	0.7	-0.1	-0.0	0.3	-0.2	-0.3	0.5	-0.3	0.4	-0.2	0.8
Body fat percentage	0.1	0.3	0.8	-0.1	-0.1	-0.3	-0.8	-0.8	-0.9	-0.8	0.7	0.1	-0.0
Age at first live birth	0.1	0.2	0.5	-0.4	-0.7	0.2	0.6	0.5	-0.1	0.4	0.2	-0.0	0.3
Health satisfaction	0.1	0.1	0.2	-0.1	-0.3	-0.1	0.4	0.1	0.4	0.2	-0.5	0.2	0.2
Shortness of breath walking on level ground	0.1	0.1	0.7	-0.1	-0.8	-0.4	-0.1	0.1	-0.4	-0.3	-0.0	0.4	0.4
Whole body fat mass	0.1	0.5	1.4	0.4	-0.7	-1.0	-1.2	-0.4	-0.9	-0.3	-0.0	0.3	-0.3
Leg fat mass (right)	0.1	0.3	0.9	0.0	-0.7	-0.8	-0.7	-0.1	-0.9	-0.4	0.5	0.6	0.2
Long-standing illness, disability or infirmity	0.1	0.2	0.6	0.5	0.5	0.6	0.4	-0.1	0.6	0.1	-0.4	-0.3	0.8
Arm fat mass (left)	0.1	0.3	0.9	0.6	-0.9	-0.7	-0.8	-0.0	-0.7	0.0	-0.1	0.5	-0.3
Medication: Bendroflumethiazide	0.1	0.2	0.6	-0.2	0.7	0.2	0.8	-0.1	-0.5	-0.5	0.5	0.0	0.4
Ever smoked	0.1	0.1	0.3	-0.0	-0.2	-0.3	-0.6	-0.2	-0.1	-0.0	-0.1	0.6	-0.4
Unable to work because of sickness or disability	0.1	0.2	0.3	-0.3	-0.4	-0.2	-0.6	-0.5	-0.5	-0.0	0.6	-0.5	0.2
Leg fat mass (left)	0.1	0.3	0.9	0.1	-0.5	-0.8	-0.7	-0.0	-0.7	-0.2	0.7	1.0	0.2
Hair Pigment	0.0	0.8	2.6	0.1	0.7	1.6	0.4	-0.7	0.2	-0.5	1.5	-0.5	1.4
Fed-up feelings	0.0	0.1	0.3	0.0	-0.2	-0.2	-0.1	0.5	0.1	0.3	0.2	-0.5	0.3
Arm fat percentage (right)	0.0	0.2	0.6	-0.1	-0.1	-0.0	-0.6	-0.4	-0.6	-0.4	0.8	0.6	0.1
Arm fat percentage (left)	0.0	0.2	1.1	-0.2	0.0	0.4	-0.1	-0.2	-0.4	-0.4	1.0	0.4	0.2

Hub : Genes

HKDC1

Models

Trait associations