Best TWAS P=1.04e-10 · Best GWAS P=1.57e-11 conditioned to 0.00575
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Breast Mammary Tissue | PRDX3 | 0.27 | 0.00 | enet | 30 | 0.02 | 3.9e-02 | 6.7 | 5.1 | 2.9e-07 | 0.63 | 0.01 | 0.91 | FALSE |
| 2 | GTEx | Breast Mammary Tissue (Female) | PRDX3 | 0.34 | 0.11 | enet | 31 | 0.12 | 1.9e-04 | 5.8 | 6.5 | 1.0e-10 | 0.64 | 0.03 | 0.74 | TRUE |
| 3 | GTEx | Esophagus Gastroesophageal Junction | FAM45A | 0.24 | 0.13 | enet | 51 | 0.09 | 2.7e-04 | 6.0 | 5.5 | 4.6e-08 | 0.30 | 0.03 | 0.81 | TRUE |
| 4 | GTEx | Esophagus Gastroesophageal Junction | BAG3 | 0.44 | 0.32 | lasso | 8 | 0.32 | 2.1e-12 | 3.8 | 5.1 | 2.7e-07 | 0.26 | 0.99 | 0.01 | FALSE |