TWAS
hub
About
Usage
Models
Genes
Traits
[Hub]/) :
Traits
:
Comparative height size at age 10
:
←
→
chr10:120,164,251-122,133,913
Best TWAS P=1.04e-10 · Best GWAS P=1.57e-11 conditioned to 0.00575
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
2
GTEx
Breast Mammary Tissue (Female)
PRDX3
0.34
0.11
enet
31
0.12
1.9e-04
5.8
6.5
1.0e-10
0.64
0.03
0.74
TRUE
3
GTEx
Esophagus Gastroesophageal Junction
FAM45A
0.24
0.13
enet
51
0.09
2.7e-04
6.0
5.5
4.6e-08
0.30
0.03
0.81
TRUE
4
GTEx
Esophagus Gastroesophageal Junction
BAG3
0.44
0.32
lasso
8
0.32
2.1e-12
3.8
5.1
2.7e-07
0.26
0.99
0.01
FALSE
1
GTEx
Breast Mammary Tissue
PRDX3
0.27
0.00
enet
30
0.02
3.9e-02
6.7
5.1
2.9e-07
0.63
0.01
0.91
FALSE