[Hub]/) : Traits : Comparative height size at age 10 : ← →

chr15:64,977,145-66,778,617

Best TWAS P=5.33e-10 · Best GWAS P=3.56e-10 conditioned to 0.198

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex DENND4A 0.06 0.05 enet 18 0.05 7.1e-07 6.1 5.9 3.8e-09 0.91 0.03 0.97 FALSE
2 GTEx Artery Tibial DENND4A 0.05 0.01 enet 8 0.02 8.3e-03 4.9 5.7 1.4e-08 0.93 0.04 0.89 FALSE
3 GTEx Brain Cerebellar Hemisphere IGDCC4 0.19 0.12 lasso 7 0.10 1.2e-03 6.0 -5.5 3.3e-08 -0.94 0.04 0.92 FALSE
4 GTEx Cells Transformed fibroblasts DENND4A 0.08 0.06 lasso 2 0.04 3.3e-04 6.0 -6.0 2.5e-09 -0.97 0.04 0.95 FALSE
5 The Cancer Genome Atlas Breast Invasive Carcinoma DENND4A 0.01 0.01 blup 68 0.01 7.5e-03 5.3 -6.0 2.7e-09 -0.83 0.02 0.28 FALSE
6 The Cancer Genome Atlas Breast Invasive Carcinoma DPP8 0.08 0.02 lasso 4 0.05 6.1e-10 4.9 -5.3 1.2e-07 -0.73 0.16 0.84 FALSE
7 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma DENND4A 0.04 0.01 blup 68 0.01 8.0e-03 -3.3 -5.4 6.5e-08 -0.61 0.04 0.09 FALSE
8 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma PTPLAD1 0.05 0.01 enet 10 0.02 4.3e-03 -3.2 -5.6 2.7e-08 -0.68 0.04 0.17 FALSE
9 The Cancer Genome Atlas Ovarian Serous Cystadenocarcinoma DENND4A 0.04 0.02 blup 67 0.02 1.3e-02 4.9 -6.2 5.3e-10 -0.94 0.02 0.60 TRUE
10 The Cancer Genome Atlas Ovarian Serous Cystadenocarcinoma DPP8 0.07 0.03 blup 53 0.01 5.4e-02 -3.4 -5.3 8.8e-08 -0.63 0.01 0.25 FALSE
11 The Cancer Genome Atlas Testicular Germ Cell Tumors DENND4A 0.09 0.05 lasso 4 0.03 3.3e-02 6.0 -6.0 1.9e-09 -0.96 0.02 0.62 FALSE