Best TWAS P=8.11e-09 · Best GWAS P=5.85e-09 conditioned to 2.78e-10
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | AAGAB | 0.06 | 0.05 | enet | 11 | 0.05 | 3.2e-07 | -5.3 | -5.2 | 2.3e-07 | 0.14 | 0.13 | 0.87 | FALSE |
| 2 | The Cancer Genome Atlas | Bladder Urothelial Carcinoma | IQCH | 0.13 | 0.07 | blup | 112 | 0.10 | 5.2e-09 | -4.4 | 5.2 | 1.5e-07 | -0.07 | 0.13 | 0.86 | FALSE |
| 3 | The Cancer Genome Atlas | Breast Invasive Carcinoma | IQCH | 0.06 | 0.05 | blup | 112 | 0.06 | 5.2e-12 | -5.2 | 5.3 | 1.4e-07 | -0.09 | 0.05 | 0.95 | FALSE |
| 4 | The Cancer Genome Atlas | Colon Adenocarcinoma | IQCH | 0.08 | 0.02 | blup | 111 | 0.05 | 4.2e-04 | -4.5 | 5.4 | 5.9e-08 | -0.09 | 0.10 | 0.79 | FALSE |
| 5 | The Cancer Genome Atlas | Pancreatic Adenocarcinoma | IQCH | 0.35 | 0.04 | blup | 112 | 0.12 | 1.5e-05 | -4.4 | 5.8 | 8.1e-09 | -0.08 | 0.10 | 0.80 | TRUE |