TWAS hub - IQCH

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.1290	0.0300	1.8e-11	0.106	0.098	0.083	0.098	0.093	7.7e-13	6.4e-12	2.4e-10	5.9e-12	1.9e-11
2	METSIM	Adipose	0.0355	0.0176	2.5e-03	0.022	0.021	0.005	0.021	0.017	2.4e-04	3.7e-04	4.5e-02	3.3e-04	9.8e-04
3	TCGA	Bladder Urothelial Carcinoma	0.1310	0.0580	1.3e-08	0.070	0.103	0.097	NA	0.090	1.4e-06	5.2e-09	1.5e-08	NA	5.1e-08
4	TCGA	Breast Invasive Carcinoma	0.0601	0.0262	2.8e-11	0.050	0.058	0.056	NA	0.050	1.4e-10	5.2e-12	1.2e-11	NA	1.8e-10
5	TCGA	Colon Adenocarcinoma	0.0840	0.0430	2.9e-04	0.025	0.055	0.054	NA	0.046	1.4e-02	4.2e-04	4.7e-04	NA	1.1e-03
6	TCGA	Glioblastoma Multiforme	0.1890	0.0840	1.4e-04	0.136	0.073	0.115	NA	0.010	6.3e-05	3.0e-03	2.4e-04	NA	1.6e-01
7	TCGA	Head and Neck Squamous Cell Carcinoma	0.0640	0.0365	3.1e-05	0.038	0.034	0.030	NA	0.022	4.0e-05	1.0e-04	2.6e-04	NA	1.5e-03
8	TCGA	Kidney Renal Clear Cell Carcinoma	0.1241	0.0500	8.4e-13	0.098	0.112	0.117	NA	0.098	3.8e-11	1.6e-12	4.0e-13	NA	3.6e-11
9	TCGA	Kidney Renal Papillary Cell Carcinoma	0.1300	0.0640	5.3e-05	0.014	0.080	0.066	NA	0.054	4.9e-02	2.4e-05	1.3e-04	NA	4.7e-04
10	TCGA	Brain Lower Grade Glioma	0.0483	0.0236	1.5e-05	0.036	0.045	0.035	NA	0.025	5.0e-05	7.7e-06	7.1e-05	NA	6.4e-04
11	TCGA	Liver Hepatocellular Carcinoma	0.1040	0.0740	3.5e-03	0.013	0.030	0.024	NA	0.027	7.6e-02	1.4e-02	2.5e-02	NA	1.9e-02
12	TCGA	Lung Adenocarcinoma	0.0431	0.0281	8.7e-04	0.021	0.011	0.011	NA	-0.002	1.5e-03	1.8e-02	1.6e-02	NA	7.9e-01
13	TCGA	Lung Squamous Cell Carcinoma	0.0435	0.0262	6.4e-04	0.019	0.031	0.031	NA	0.031	3.0e-03	1.8e-04	1.6e-04	NA	1.8e-04
14	TCGA	Ovarian Serous Cystadenocarcinoma	0.1140	0.0580	1.2e-06	0.099	0.102	0.097	NA	0.087	3.4e-07	2.3e-07	4.6e-07	NA	1.8e-06
15	TCGA	Pancreatic Adenocarcinoma	0.3510	0.1730	1.6e-05	0.040	0.116	0.099	NA	0.046	8.8e-03	1.5e-05	6.0e-05	NA	5.4e-03
16	TCGA	Prostate Adenocarcinoma	0.1884	0.0692	4.4e-16	0.066	0.164	0.149	NA	0.147	2.1e-07	7.4e-17	2.5e-15	NA	3.6e-15
17	TCGA	Soft Tissue Sarcoma	0.0840	0.0430	1.1e-04	0.086	0.064	0.078	NA	0.076	8.9e-06	1.2e-04	2.3e-05	NA	2.9e-05
18	TCGA	Stomach Adenocarcinoma	0.0840	0.0630	2.0e-03	0.025	0.038	0.011	NA	0.020	5.7e-03	9.2e-04	4.7e-02	NA	1.3e-02
19	TCGA	Thyroid Carcinoma	0.1460	0.0520	1.1e-16	0.169	0.147	0.173	NA	0.145	3.3e-16	3.6e-14	1.3e-16	NA	5.6e-14

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17	18	19
Respiratory disease	14.4	32.1	61.5	7.8	1.9	7.3	7.8	7.7	5.6	5.7	5.5	3.2	6.5	2.1	1.8	5.4	6.2	6.9	1.6	4.5	6.3	6.1
Body fat percentage	13.1	51.6	77.1	6.8	6.2	6.9	8.5	6.7	7.3	7.3	7.0	5.5	7.3	7.3	7.6	8.5	7.6	8.8	6.7	5.2	7.8	6.5
Trunk fat percentage	13.0	52.3	80.8	7.2	6.0	7.2	8.8	6.9	7.2	7.4	7.1	5.5	7.4	7.1	7.3	8.6	7.6	9.0	6.4	5.2	8.0	6.4
Chronic bronchitis/emphysema (father)	12.9	15.1	22.1	4.1	2.9	4.1	4.4	4.5	4.2	3.9	3.8	2.9	4.6	3.1	3.0	3.8	4.5	3.9	2.8	3.8	3.8	4.7
Trunk fat mass	12.8	54.8	81.4	6.8	6.2	7.2	8.8	7.1	7.5	7.5	7.4	5.8	7.7	7.3	7.8	8.7	7.8	9.0	6.6	5.5	8.0	6.9
Number of self-reported non-cancer illnesses	12.4	21.5	36.0	5.0	2.7	5.4	6.0	5.8	5.1	4.8	4.6	3.0	5.5	2.9	2.2	4.6	5.3	5.7	2.5	4.3	4.9	5.0
Waist circumference	12.2	44.5	63.6	5.7	5.2	6.3	7.5	6.4	7.1	6.8	6.7	5.4	7.0	6.8	7.3	7.4	7.3	8.0	6.2	5.2	7.0	6.7
Whole body fat mass	12.2	50.7	73.0	6.2	6.0	6.6	8.2	6.7	7.4	7.2	7.0	5.5	7.3	7.3	7.9	8.5	7.6	8.5	6.6	5.4	7.6	6.8
Arm fat percentage (right)	11.9	46.8	66.9	6.2	5.5	6.3	7.9	6.3	7.2	6.8	6.7	5.2	7.1	7.2	7.5	8.2	7.5	8.2	6.5	5.0	7.2	6.5
Past tobacco smoking	11.7	21.4	30.9	-5.3	-3.2	-4.6	-5.5	-5.2	-5.3	-4.8	-4.1	-3.2	-5.3	-3.7	-3.7	-5.0	-5.6	-4.4	-3.5	-4.4	-4.5	-5.5
Long-standing illness, disability or infirmity	11.5	17.6	28.9	4.0	2.4	4.7	4.6	5.0	4.6	4.3	4.3	3.5	4.6	3.4	2.9	3.7	4.4	5.4	2.8	4.4	4.5	4.8
Arm fat percentage (left)	11.1	44.3	65.9	6.1	5.3	6.1	7.7	6.1	7.0	6.6	6.4	5.0	6.8	7.0	7.4	8.1	7.3	8.0	6.4	4.8	7.0	6.3
Leg fat mass (right)	10.5	40.7	60.3	5.3	5.5	5.6	7.2	5.7	6.7	6.4	6.1	4.9	6.4	6.9	7.5	7.8	6.9	7.5	6.3	4.7	6.7	6.1
Leg fat percentage (right)	10.3	37.3	54.1	5.3	5.5	5.5	6.9	5.4	6.3	6.1	5.9	4.9	6.0	6.7	7.0	7.3	6.4	7.4	6.1	4.5	6.6	5.5
Leg fat mass (left)	10.1	39.6	57.4	5.1	5.5	5.5	7.0	5.6	6.6	6.3	6.0	4.9	6.4	6.9	7.4	7.6	6.8	7.3	6.3	4.7	6.5	6.0
Asthma	9.8	19.2	38.0	6.0	1.5	5.6	5.9	6.2	4.7	4.3	4.0	2.1	4.9	1.5	0.8	4.1	4.9	5.4	1.1	3.9	5.0	4.9
Asthma (self-reported)	9.8	19.5	38.4	6.1	1.4	5.6	6.1	6.2	4.7	4.4	4.0	2.1	5.0	1.4	0.8	4.2	5.0	5.2	1.1	3.8	4.9	4.9
Arm fat mass (left)	9.8	40.1	59.5	5.4	5.0	5.6	7.1	5.8	6.8	6.3	6.1	4.8	6.5	6.7	7.3	7.7	7.0	7.4	6.0	4.7	6.5	6.3
Leg fat percentage (left)	9.8	35.4	49.6	5.0	5.3	5.4	6.7	5.2	6.1	6.0	5.7	4.8	5.9	6.6	6.8	7.0	6.2	7.0	6.1	4.4	6.4	5.4
Arm fat mass (right)	9.7	40.0	57.5	5.3	5.1	5.6	7.1	5.8	6.8	6.3	6.1	4.9	6.6	6.7	7.3	7.6	7.0	7.4	6.1	4.7	6.4	6.2
Fractured/broken bones in last 5 years	9.3	12.1	20.6	3.3	2.0	3.2	4.0	4.0	4.2	3.3	3.4	2.1	3.3	2.8	3.3	4.5	3.9	4.5	1.9	3.2	3.9	3.5
Smoking status: Previous	9.2	13.8	21.4	3.7	3.0	3.5	4.1	4.0	4.4	3.7	3.3	2.8	4.2	3.3	3.3	3.8	4.4	3.4	3.1	3.9	3.4	4.6
Taking other prescription medications	9.0	13.8	23.1	3.9	2.6	4.7	4.5	4.3	3.5	4.1	4.3	3.4	4.3	2.7	2.1	2.9	3.7	4.8	2.4	3.4	4.1	3.5
Number of operations (self-reported)	8.6	12.8	19.3	4.4	2.6	4.2	4.1	4.4	3.9	3.7	3.7	2.8	4.1	2.3	1.8	2.7	3.8	4.1	2.1	3.8	3.6	4.0
Worry too long after embarrassment	8.3	14.0	24.6	-4.1	-1.6	-3.4	-4.5	-4.1	-4.3	-3.7	-3.5	-2.2	-4.1	-3.1	-4.0	-5.0	-4.6	-3.6	-2.6	-3.2	-3.7	-4.1
Age when periods started (menarche)	8.2	19.6	31.6	-3.8	-2.8	-4.1	-4.9	-4.8	-5.3	-4.5	-4.3	-3.0	-5.0	-4.1	-4.5	-5.0	-5.6	-4.2	-3.8	-3.7	-4.4	-5.2
Lung FVC	7.6	38.7	64.3	7.9	3.7	7.1	8.0	7.5	6.8	6.5	6.1	4.0	6.9	4.1	3.5	6.3	7.1	6.9	3.7	5.5	6.9	6.3
Had major operations	7.6	8.9	11.8	3.3	1.8	3.2	3.1	3.4	3.3	3.1	3.2	2.6	3.2	2.7	2.6	2.6	3.3	3.1	2.4	2.9	3.2	3.4
Hip circumference	7.5	32.2	54.1	3.5	4.2	4.8	5.7	5.1	6.2	5.6	5.6	4.8	5.8	6.5	7.4	6.5	6.1	6.4	5.7	5.0	5.7	6.0
Hearing difficulty/problems: Yes	7.4	11.3	16.2	2.7	3.3	3.5	3.0	3.4	3.7	3.4	3.8	3.4	3.7	3.4	3.2	2.0	3.4	3.2	3.2	3.9	3.1	4.0
Townsend deprivation index at recruitment	6.9	9.7	16.2	2.3	2.0	2.5	3.3	3.3	4.0	3.1	2.8	2.0	3.0	3.2	3.4	4.0	3.9	3.0	2.7	2.8	3.2	3.6
Weight	6.9	33.9	52.0	4.4	4.3	5.0	6.4	5.5	6.4	5.7	5.6	4.4	6.0	6.2	7.1	7.2	6.5	6.8	5.4	4.6	5.8	6.0
Headache pain in last month	6.9	11.9	16.4	-2.9	-3.2	-3.2	-3.5	-2.9	-3.5	-3.6	-3.7	-3.3	-3.9	-3.9	-4.0	-3.0	-3.8	-3.4	-3.9	-2.9	-3.2	-3.5
Sensitivity / hurt feelings	6.8	11.6	16.4	-3.5	-1.2	-3.0	-3.8	-3.5	-4.0	-3.4	-3.3	-2.4	-3.5	-3.3	-4.0	-4.0	-3.9	-3.4	-2.8	-3.3	-3.5	-3.7
Nervous feelings	6.8	12.7	20.5	-3.6	-1.2	-3.7	-4.5	-4.1	-3.9	-3.7	-3.5	-2.4	-4.1	-2.6	-3.4	-4.2	-4.3	-3.6	-2.3	-2.9	-3.6	-4.1
Smoking Status	6.5	15.6	24.9	4.6	2.5	3.9	5.0	4.5	4.6	4.0	3.2	2.4	4.6	2.9	3.0	4.6	4.9	3.8	2.7	3.6	3.8	4.8
Ever smoked	6.5	11.3	17.7	4.1	2.1	3.3	4.0	3.8	4.0	3.3	2.7	2.2	3.8	2.7	2.7	3.7	3.9	3.4	2.5	3.5	3.2	4.2
Medication: Ventolin 100micrograms inhaler	6.4	8.2	16.4	3.7	0.7	3.7	4.0	4.0	3.1	2.7	2.8	1.4	3.1	0.7	0.6	2.8	3.0	3.8	0.4	2.5	3.2	3.0
Maternal smoking around birth	6.1	8.8	13.4	3.2	2.3	3.3	3.7	2.9	2.8	3.1	3.0	2.6	3.6	2.7	2.7	2.6	3.2	2.9	2.8	2.6	3.0	3.0
Eye problems/disorders: Glaucoma	6.1	7.2	13.8	-2.2	-1.0	-2.4	-2.9	-3.1	-3.5	-2.7	-2.2	-1.6	-3.2	-2.3	-2.3	-2.9	-3.5	-1.9	-2.1	-3.2	-2.5	-3.7
Allergy	6.0	13.8	30.5	-5.5	0.1	-4.9	-5.3	-5.5	-3.7	-3.5	-3.3	-1.3	-4.1	-0.5	0.2	-3.5	-4.0	-4.8	-0.2	-2.8	-4.3	-3.9
Chronic bronchitis/emphysema (mother)	5.9	6.9	13.0	3.5	0.3	2.6	3.3	3.6	3.3	2.4	2.3	0.8	3.0	1.1	1.3	3.2	3.4	2.8	0.7	2.3	2.5	3.3
Suffer from ‘nerves’	5.9	9.3	17.3	-2.6	-1.7	-2.5	-3.4	-3.7	-4.0	-2.8	-3.0	-1.4	-3.3	-2.2	-3.3	-4.2	-4.0	-3.0	-1.5	-2.9	-2.8	-3.7
BMI	5.8	33.9	66.7	4.4	4.1	4.0	6.2	5.3	7.2	5.4	4.9	3.5	6.0	6.5	7.4	8.2	7.5	5.5	5.9	4.2	5.3	6.5
Neuroticism	5.6	13.6	28.6	-4.9	-0.9	-3.1	-4.9	-4.2	-4.6	-3.3	-3.2	-1.3	-4.2	-2.3	-3.4	-5.3	-5.0	-3.6	-1.9	-2.4	-3.3	-4.1
Comparative body size at age 10	5.5	15.2	35.6	3.4	1.7	2.6	4.5	4.0	5.1	3.8	2.8	1.6	4.7	3.7	3.9	5.6	6.0	2.3	3.7	3.0	3.1	4.9
Vascular/heart problems diagnosed by doctor	5.3	14.4	23.0	-3.7	-2.5	-3.6	-4.7	-4.2	-4.6	-3.8	-3.7	-2.2	-4.4	-3.1	-3.0	-4.5	-4.8	-4.2	-2.9	-3.0	-3.6	-4.1
Hair/balding pattern: Pattern 4	5.2	12.7	25.0	-3.9	-1.4	-3.4	-3.9	-5.0	-4.8	-3.3	-3.6	-1.6	-3.8	-1.9	-2.5	-4.1	-4.6	-3.6	-1.0	-3.5	-3.5	-4.7
Body mass index (BMI)	5.1	21.5	41.1	3.2	3.3	3.1	4.9	3.8	5.5	4.3	4.0	3.1	4.6	5.6	6.2	6.4	5.6	4.9	5.1	3.2	4.3	4.8
Neuroticism score	5.1	10.6	16.8	-4.0	-1.1	-3.1	-4.1	-3.5	-3.8	-3.1	-3.1	-1.9	-3.7	-2.5	-3.2	-4.1	-4.0	-3.3	-2.1	-3.0	-3.1	-3.6
High blood pressure	5.0	14.0	21.6	3.6	2.9	3.8	4.6	4.1	4.3	3.9	3.9	2.5	4.4	3.2	3.0	4.0	4.7	3.9	3.0	3.0	3.6	3.9
Pulse wave Arterial Stiffness index	5.0	5.8	8.5	2.5	2.3	2.5	2.4	2.5	2.6	2.4	2.6	2.0	2.7	2.2	1.7	1.9	2.6	2.9	2.0	2.4	2.3	2.6
Heel T-Score	4.9	38.7	56.0	-5.7	-5.1	-7.0	-7.3	-7.5	-6.7	-6.2	-7.0	-4.5	-6.9	-4.3	-5.1	-6.2	-6.7	-7.4	-3.3	-6.0	-6.7	-6.7
Hypertension (Self-reported)	4.6	12.8	18.7	3.2	2.8	3.6	4.3	3.8	4.1	3.7	3.8	2.6	4.3	3.1	3.0	3.7	4.3	3.9	2.9	3.1	3.5	3.7
Body Mass Index (BMI) (2010)	4.5	6.2	19.6	3.1	0.9	1.4	2.9	2.7	3.6	2.0	1.2	0.3	2.4	1.9	2.4	4.4	3.6	1.4	1.6	2.2	2.1	3.1
Lung cancer (father)	4.5	5.2	8.6	1.7	1.6	2.6	2.5	2.3	1.9	2.7	2.9	2.5	2.5	2.2	2.5	1.9	2.2	2.7	1.9	1.8	2.5	2.0
Worry (Nagel 2018)	4.3	9.1	22.8	-3.5	-0.8	-2.6	-4.1	-3.4	-3.5	-2.9	-2.7	-1.2	-3.2	-1.9	-3.2	-4.8	-4.0	-3.0	-1.5	-1.8	-2.9	-3.1
Heel bone mineral density (BMD) T-score, automated (right)	4.3	10.0	15.8	-2.7	-2.7	-4.0	-3.4	-3.2	-2.6	-3.6	-3.7	-3.5	-3.7	-2.9	-2.6	-1.8	-2.9	-3.2	-2.9	-3.3	-3.5	-2.9
Birth weight of first child	4.3	7.9	11.8	3.1	2.5	3.3	3.0	3.4	2.8	3.1	3.1	2.5	3.4	2.1	1.7	1.7	3.1	2.7	2.0	2.8	2.8	3.3
Diverticular disease/diverticulitis (self-reported)	4.2	4.9	8.9	1.2	1.6	2.5	2.2	2.5	2.4	2.4	2.5	2.3	2.6	1.9	2.0	1.3	2.2	2.1	1.7	3.0	2.2	2.7
Medication: Ramipril	4.1	5.3	12.5	3.5	1.3	2.5	3.1	2.8	2.6	2.3	2.4	1.1	2.7	1.3	0.8	2.2	2.9	2.9	1.3	1.2	2.3	2.3
Pulse wave reflection index	4.1	5.1	7.6	2.4	1.8	2.3	2.0	2.3	2.5	2.3	2.4	2.1	2.2	2.4	1.8	1.9	2.1	2.8	2.0	2.6	2.5	2.2
Overall health rating	4.1	8.9	13.9	3.7	2.4	3.5	3.4	3.0	2.8	3.2	2.7	2.8	3.2	2.8	1.9	2.3	2.7	3.5	2.9	2.9	3.3	3.0
Waist Hip Ratio (WHR)	4.0	18.0	42.1	6.5	3.9	5.6	5.8	5.0	3.3	4.5	4.6	3.1	4.7	2.0	1.5	3.3	4.0	5.8	1.9	2.4	4.8	3.4
Supplements: Vitamin C	3.8	4.5	8.4	-1.5	-1.4	-1.5	-1.7	-2.0	-2.8	-2.0	-1.9	-1.6	-1.9	-2.6	-2.7	-2.3	-2.3	-1.7	-2.1	-2.9	-2.2	-2.5
Bipolar Disorder (2018)	3.7	5.8	10.2	1.1	2.1	2.8	2.2	2.5	2.2	2.7	2.4	2.7	3.0	2.4	2.1	1.1	2.4	1.8	2.5	3.1	2.4	3.2
Heel bone mineral density (BMD) T-score, automated (left)	3.7	8.4	13.5	-2.5	-2.2	-3.7	-3.4	-3.2	-2.5	-3.4	-3.4	-2.9	-3.6	-2.3	-2.3	-2.1	-3.0	-2.8	-2.2	-2.9	-3.2	-2.9
Worrier / anxious feelings	3.7	6.9	10.5	-3.2	-1.0	-2.5	-3.2	-2.6	-2.9	-2.6	-2.4	-1.9	-2.7	-2.4	-2.9	-3.1	-2.9	-2.7	-2.2	-2.3	-2.7	-2.8
Medication: Paracetamol	3.7	6.1	11.9	-1.9	-2.8	-2.0	-2.5	-1.9	-2.3	-2.6	-2.1	-2.3	-2.7	-2.8	-3.4	-2.6	-2.8	-1.6	-2.9	-2.1	-2.1	-2.6
Pulse wave peak to peak time	3.7	4.3	6.2	-2.2	-2.0	-2.1	-2.0	-2.2	-2.4	-2.1	-2.2	-1.7	-2.3	-2.0	-1.5	-1.6	-2.3	-2.5	-1.8	-2.2	-2.0	-2.3
Age at first live birth	3.6	6.5	10.9	-1.4	-2.2	-2.6	-2.1	-2.1	-2.2	-2.8	-2.6	-3.1	-2.6	-3.1	-3.3	-1.7	-2.1	-2.0	-3.0	-3.0	-2.6	-2.7
Mother’s age at death	3.6	4.5	9.5	-1.8	-1.4	-2.2	-2.0	-2.5	-2.7	-1.9	-2.1	-1.7	-2.3	-1.8	-1.7	-1.5	-2.3	-2.2	-1.6	-2.7	-2.0	-3.1
Diastolic blood pressure, automated reading	3.6	11.2	18.3	3.5	2.2	3.6	4.3	3.5	3.6	3.5	3.2	2.5	4.0	2.8	2.7	3.6	4.0	3.6	2.9	2.5	3.3	3.6
Other serious medical condition/disability diagnosed by doctor	3.5	4.5	7.8	2.4	1.6	2.4	2.3	2.7	2.4	2.2	2.0	1.5	2.4	1.3	0.6	1.8	2.3	2.8	1.1	2.5	2.2	2.5
Comparative height size at age 10	3.5	19.3	33.3	3.9	3.1	5.2	5.3	5.4	4.4	4.4	5.0	3.4	5.0	2.8	3.4	4.0	4.5	5.8	2.2	4.0	4.8	4.9
Illnesses of siblings: Diabetes	3.5	4.3	7.2	0.6	1.7	1.4	1.7	2.1	2.6	2.1	1.9	1.5	2.1	2.3	2.6	2.7	2.6	1.9	1.8	2.1	2.0	2.5
Age at First Birth	3.4	4.9	11.1	-0.6	-2.9	-1.9	-1.2	-1.3	-1.6	-2.5	-2.3	-3.0	-1.8	-3.3	-2.9	-1.0	-1.5	-1.9	-3.2	-2.4	-2.4	-1.6
Forced vital capacity (FVC)	3.4	13.1	27.8	5.2	1.2	4.4	5.3	4.8	3.7	3.5	3.1	1.5	4.0	1.1	1.1	4.1	3.9	4.5	0.7	3.1	4.0	3.6
Forced expiratory volume in 1-second (FEV1), predicted percentage	3.4	7.1	10.0	2.6	2.5	2.8	3.0	3.0	3.1	2.9	2.6	2.0	2.9	2.3	1.9	2.4	3.2	2.5	2.2	2.5	2.9	3.0
Wheeze or whistling in the chest in last year	3.3	5.8	13.0	3.5	0.3	3.3	3.6	3.4	2.4	2.2	2.0	1.0	2.7	0.4	-0.0	2.5	2.4	3.1	0.2	2.1	2.8	2.5
Blood Eosinophil Count	3.2	24.8	58.2	7.2	-0.5	5.3	6.7	7.6	5.8	4.4	4.1	0.8	5.0	0.4	1.2	6.8	6.1	6.0	-0.8	3.5	5.3	5.6
Medication: Bendroflumethiazide	3.2	4.9	8.6	2.2	2.9	2.0	2.2	2.2	2.5	2.1	2.4	1.7	2.5	2.0	2.1	2.0	2.5	2.3	1.8	1.8	1.9	2.4
Allergy or Eczema	3.1	8.1	20.9	4.6	-0.0	4.0	3.9	4.3	2.6	2.8	2.7	1.3	3.2	0.2	-0.3	2.2	2.9	3.5	0.1	2.1	3.2	3.0
Serious illness, injury or assault to yourself	3.1	3.7	8.7	1.1	-0.1	2.1	2.1	2.4	2.4	1.8	2.1	1.4	1.9	1.5	1.5	2.1	1.9	3.0	0.9	2.1	2.2	2.2
Glaucoma (self-reported)	3.0	3.6	9.0	-1.1	-0.3	-1.3	-1.7	-2.4	-2.9	-1.7	-1.2	-0.7	-2.0	-1.5	-1.7	-2.5	-2.7	-1.1	-1.2	-2.5	-1.6	-3.0
Guilty feelings	3.0	4.4	8.8	-2.9	-0.5	-1.5	-2.3	-2.4	-3.0	-1.8	-1.7	-0.8	-2.2	-1.6	-2.1	-2.8	-2.8	-1.7	-1.2	-2.1	-1.8	-2.7
Hair/balding pattern: Pattern 2	2.9	3.7	6.6	-1.3	-0.5	-2.0	-2.0	-2.5	-2.6	-1.9	-2.2	-1.2	-2.3	-1.5	-1.4	-1.7	-2.6	-1.7	-1.4	-2.0	-2.0	-2.5
Leg fat-free mass (left)	2.8	14.7	25.4	2.5	2.3	2.9	4.0	3.8	4.7	3.6	3.5	2.6	4.0	3.9	5.0	5.0	4.7	3.9	3.3	3.3	3.5	4.7
Leg predicted mass (left)	2.8	14.9	25.8	2.5	2.3	2.9	4.0	3.8	4.7	3.6	3.6	2.6	4.1	3.9	5.0	5.1	4.7	4.0	3.3	3.3	3.5	4.7
Medication: Omeprazole	2.8	3.3	5.2	1.6	2.3	1.8	1.5	1.8	1.8	1.7	2.1	1.9	1.9	1.7	1.8	1.2	1.6	2.3	1.4	2.1	1.7	2.0
Mineral and other dietary supplements	2.8	3.7	6.0	0.7	0.9	1.5	1.8	1.9	2.4	2.0	1.8	1.5	1.8	2.3	2.4	2.3	2.2	1.7	2.0	2.0	2.1	2.2
Medication: Paracetamol	2.8	4.3	9.4	-1.2	-2.4	-1.7	-2.0	-1.4	-1.7	-2.3	-1.8	-2.2	-2.2	-2.6	-3.1	-2.0	-2.1	-1.1	-2.8	-1.8	-1.8	-2.1
Cardiovascular Disease	2.7	9.0	19.2	2.6	1.7	2.6	4.0	3.7	4.0	2.6	2.7	0.9	3.8	1.6	2.2	4.3	4.4	3.1	1.3	2.1	2.3	3.7
Number of treatments/medications taken	2.7	4.9	10.1	2.9	2.0	2.7	2.8	2.6	2.1	2.2	2.6	1.7	2.6	1.2	1.1	1.8	2.3	3.2	1.1	1.4	2.1	2.1
Breast Cancer	2.6	6.4	13.4	-1.6	-3.7	-3.0	-2.3	-2.2	-2.0	-2.7	-2.7	-3.1	-2.6	-2.6	-1.9	-0.8	-1.8	-3.2	-2.6	-2.6	-2.6	-2.4
Basal metabolic rate	2.6	14.6	25.9	2.2	2.5	2.9	3.8	3.7	4.6	3.6	3.6	2.8	4.0	4.0	5.1	4.7	4.5	4.0	3.4	3.5	3.4	4.7
Medication: Omeprazole (e.g. Zanprol)	2.6	3.2	5.5	1.7	1.6	1.8	1.6	1.9	2.1	1.7	1.9	1.5	1.7	1.7	1.5	1.5	1.7	2.3	1.3	2.0	1.9	2.0
Falls in the last year	2.5	3.4	7.6	0.6	1.1	2.6	1.7	2.0	1.3	2.2	2.5	2.5	1.8	1.6	1.1	0.4	1.1	2.8	1.4	2.1	2.4	1.4
Forced vital capacity (FVC), Best measure	2.4	8.7	21.6	4.6	1.2	3.8	4.4	4.0	2.9	2.8	2.5	1.2	3.4	0.5	0.4	3.0	3.1	3.7	0.3	2.4	3.1	3.0
Medication: Seretide 50 evohaler	2.4	2.8	6.8	2.1	-0.7	2.5	2.6	2.5	1.5	1.5	1.7	0.5	2.0	-0.1	-0.5	1.4	1.7	2.4	-0.1	0.9	1.9	1.6
Illnesses of siblings	2.3	3.2	7.6	-1.1	-1.2	-1.0	-1.6	-2.3	-2.8	-1.6	-1.6	-0.4	-1.9	-1.4	-1.5	-2.7	-2.7	-1.7	-0.8	-1.8	-1.5	-2.3
Seen a psychiatrist for nerves, anxiety, tension or depression	2.3	3.0	5.3	1.3	0.7	1.5	1.7	1.7	2.2	1.6	1.4	1.2	1.7	1.9	1.6	1.9	1.7	1.9	1.6	2.3	2.0	2.0
Average weekly red wine intake	2.3	3.3	5.6	1.1	1.2	2.1	2.1	1.9	1.7	2.1	2.2	1.7	2.4	1.8	1.5	1.5	2.1	1.6	1.8	1.8	1.9	1.6
Ever had stillbirth, spontaneous miscarriage or termination	2.3	2.4	6.6	-0.9	-2.1	-2.0	-0.9	-1.0	-0.5	-1.9	-2.0	-2.6	-1.4	-1.9	-1.3	0.3	-0.5	-1.5	-1.9	-1.8	-1.7	-0.9
Leg predicted mass (right)	2.3	12.3	22.1	2.0	1.9	2.6	3.5	3.4	4.3	3.2	3.2	2.4	3.7	3.7	4.7	4.6	4.3	3.4	3.1	3.2	3.1	4.4
Depression (Nagel 2018)	2.2	3.3	7.3	-1.7	-0.2	-1.6	-2.5	-2.2	-2.3	-1.8	-1.5	-0.6	-2.1	-1.2	-1.4	-2.7	-2.5	-1.9	-1.0	-1.3	-1.8	-1.9
Crohns Disease (2012)	2.2	3.5	10.1	3.2	0.8	2.2	2.8	2.7	1.8	1.8	1.5	0.5	2.2	0.1	0.5	2.3	2.4	1.5	0.1	1.2	1.8	2.1
Emphysema/chronic bronchitis	2.2	2.5	6.7	2.6	1.0	2.3	2.2	1.8	1.0	1.6	1.9	1.3	1.6	0.7	0.4	1.0	1.1	2.6	0.7	0.7	2.0	1.0
Leg fat-free mass (right)	2.2	11.6	21.1	1.9	1.8	2.4	3.4	3.4	4.3	3.1	3.1	2.2	3.6	3.5	4.6	4.5	4.3	3.3	3.0	3.1	3.0	4.3
Supplements: Zinc	2.1	2.3	6.9	-1.7	-0.1	-1.2	-2.0	-1.7	-1.9	-1.3	-1.2	-0.4	-1.2	-1.1	-1.5	-2.6	-1.7	-1.8	-0.7	-1.0	-1.8	-1.2
Medication: Levothyroxine sodium	2.1	3.5	6.5	-1.4	-1.4	-1.8	-1.2	-1.5	-1.8	-1.9	-1.8	-2.3	-1.7	-2.5	-2.3	-0.8	-1.5	-1.4	-2.5	-2.3	-2.0	-2.2
Medication for cholesterol, blood pressure or diabetes	2.1	3.5	7.7	-1.3	-1.1	-1.5	-2.5	-1.7	-2.1	-1.7	-1.9	-1.1	-2.3	-1.6	-2.4	-2.8	-2.5	-2.0	-1.4	-1.0	-1.3	-1.9
Illness, injury, bereavement, stress in last 2 years	2.1	2.5	5.4	-1.4	-0.7	-1.6	-1.9	-1.7	-1.9	-1.5	-1.4	-1.0	-1.5	-1.5	-1.1	-1.7	-1.6	-2.3	-1.3	-1.4	-1.9	-1.8
Arm fat-free mass (left)	2.1	10.5	21.6	1.3	2.5	2.3	2.9	2.9	3.8	3.0	3.1	2.7	3.4	3.7	4.6	3.8	3.8	3.1	3.2	3.1	2.7	4.0
Hayfever, allergic rhinitis or eczema	2.0	4.4	11.3	3.3	-0.6	3.0	3.1	3.4	1.7	1.9	1.8	0.4	2.3	-0.5	-1.0	1.7	2.2	2.6	-0.7	1.1	2.3	2.1
Qualifications: nursing, teaching	2.0	3.0	4.8	-1.3	-1.1	-2.2	-2.0	-1.6	-1.2	-2.1	-1.9	-2.0	-1.9	-1.8	-1.4	-1.4	-1.4	-2.1	-1.8	-1.7	-2.2	-1.2
Osteoporosis (self-reported)	2.0	2.5	5.6	2.0	0.6	2.2	2.4	2.2	1.3	1.6	1.5	0.8	2.0	0.3	0.2	1.7	1.6	2.1	0.1	1.3	1.7	1.4
Supplements: Fish oil (including cod liver oil)	2.0	2.6	5.7	-0.9	-0.6	-1.2	-1.7	-2.0	-2.4	-1.5	-1.4	-0.7	-1.7	-1.4	-1.5	-2.1	-2.2	-1.6	-1.1	-1.5	-1.6	-2.1
Bipolar Disorder or Schizophrenia	1.9	4.7	8.7	1.7	2.0	2.2	2.2	2.4	2.2	2.4	1.9	2.0	2.6	1.9	1.9	1.8	2.5	1.7	1.9	2.6	2.0	2.9
Neuroticism (Nagel 2018)	1.9	4.5	15.9	-2.4	0.4	-1.3	-2.8	-2.6	-3.0	-1.7	-1.3	0.0	-2.2	-0.9	-2.0	-4.0	-3.2	-1.7	-0.5	-1.3	-1.6	-2.5
Alzheimer’s Disease (in father)	1.9	2.0	4.0	2.0	0.5	1.3	1.7	1.7	1.7	1.4	1.2	0.8	1.2	1.0	1.4	1.8	1.4	1.8	0.6	1.3	1.7	1.6
Ulcerative Colitis (UC)	1.9	3.5	7.0	2.6	2.2	2.5	2.3	2.2	1.3	2.0	2.1	1.8	2.0	1.0	1.0	1.1	1.5	2.6	0.9	1.2	2.0	1.7
Forced expiratory volume in 1-second (FEV1)	1.9	6.4	12.2	3.0	1.3	2.8	3.5	3.2	2.9	2.4	2.0	1.1	2.8	1.2	1.2	3.1	2.9	3.0	0.9	2.5	2.8	2.7
Heart attack/myocardial infarction (self-reported)	1.9	2.4	6.0	2.4	0.7	1.1	1.8	1.3	2.0	1.1	1.0	0.7	1.2	1.5	1.6	2.3	1.4	2.1	1.2	1.4	1.5	1.6
Irritable Bowel Disease (IBD)	1.8	4.3	10.4	3.2	2.0	2.7	2.7	2.7	1.6	2.1	2.0	1.4	2.2	0.7	0.9	1.9	2.0	2.5	0.5	1.5	2.3	2.0
Relative age voice broke	1.8	2.7	4.5	-1.2	-1.2	-1.8	-2.1	-1.4	-1.1	-2.1	-1.8	-1.6	-2.1	-1.7	-1.8	-1.6	-1.9	-1.3	-1.9	-1.0	-1.7	-1.3
Heart attack	1.8	2.4	6.1	2.5	0.7	1.1	1.8	1.3	2.0	1.1	1.0	0.8	1.1	1.5	1.6	2.2	1.4	2.1	1.2	1.3	1.5	1.5
Loneliness, isolation	1.8	2.4	4.9	0.9	1.9	1.4	0.9	1.2	1.4	1.5	1.5	1.9	1.0	2.2	2.2	1.1	1.0	1.5	1.9	1.7	1.9	1.6
Exposure to tobacco smoke at home	1.7	1.9	3.9	0.2	1.5	1.1	0.8	1.0	1.5	1.3	1.2	1.6	1.3	1.9	1.7	0.8	1.1	1.2	1.8	2.0	1.2	1.7
Medication: Ibuprofen	1.7	2.1	4.4	-0.7	-0.7	-1.2	-1.9	-1.2	-1.3	-1.5	-1.6	-1.0	-1.8	-1.5	-2.0	-2.1	-1.9	-1.1	-1.5	-0.8	-1.3	-1.2
Whole body fat-free mass	1.7	9.7	18.6	1.4	1.9	2.2	2.8	3.1	3.9	2.8	2.9	2.3	3.4	3.2	4.3	3.8	3.9	2.9	2.6	3.1	2.5	4.2
Whole body water mass	1.7	9.5	18.6	1.3	1.9	2.2	2.8	3.1	3.9	2.8	2.9	2.3	3.3	3.2	4.3	3.7	3.8	2.9	2.6	3.0	2.5	4.2
Primary Biliary Cirrhosis	1.6	2.2	3.9	1.1	1.3	1.3	1.5	1.6	1.8	1.3	1.3	1.1	1.5	1.4	1.9	1.7	1.7	1.3	1.2	1.5	1.4	2.0
Diabetes (father)	1.6	2.0	4.0	0.5	1.5	1.7	1.5	1.2	1.0	1.7	1.4	1.7	1.6	1.7	1.2	0.7	1.4	1.5	2.0	0.6	1.6	1.4
Average weekly fortified wine intake	1.6	1.9	3.7	-1.3	-0.8	-1.2	-1.6	-1.7	-1.8	-1.3	-1.3	-0.7	-1.6	-0.9	-1.2	-1.7	-1.9	-1.3	-0.7	-1.2	-1.2	-1.9
Multivitamins +/- minerals	1.6	2.0	5.5	-2.3	-1.1	-1.4	-1.8	-1.5	-1.6	-1.4	-1.0	-0.7	-1.4	-1.0	-1.0	-1.9	-1.6	-1.1	-0.9	-1.5	-1.5	-1.4
Qualifications: A levels/AS levels or equivalent	1.6	3.5	6.1	-1.9	-1.5	-2.3	-2.5	-2.2	-1.7	-2.1	-2.2	-1.5	-2.2	-1.2	-1.4	-1.8	-2.1	-2.2	-1.1	-1.3	-2.1	-1.6
Pulse rate, automated reading	1.6	5.0	9.2	3.0	2.1	2.6	2.5	2.6	2.1	2.5	2.4	1.9	2.9	1.4	1.4	1.3	2.6	1.5	1.6	2.1	1.9	2.7
Commuting to job workplace: Car/motor vehicle	1.6	1.8	4.8	1.1	1.6	1.4	1.4	0.4	0.5	1.5	1.4	1.9	1.4	1.9	1.6	0.6	0.8	1.4	2.2	0.9	1.2	0.6
Handedness (chirality/laterality): Left-handed	1.6	1.9	4.3	-1.3	0.0	-1.5	-1.9	-1.7	-1.5	-1.4	-1.4	-0.7	-2.0	-0.8	-1.0	-1.6	-2.1	-0.7	-1.0	-0.9	-1.2	-1.7
Breast cancer (self-reported)	1.6	1.9	4.3	0.9	1.8	1.5	0.9	0.7	0.6	1.6	1.8	2.0	1.6	1.9	1.5	0.1	1.0	0.9	2.1	1.1	1.2	0.9
Medication: Metformin	1.5	2.1	5.1	0.8	1.4	0.9	1.1	1.3	1.8	1.2	1.5	1.1	1.3	1.6	2.3	2.0	1.5	1.8	1.1	1.4	1.3	1.6
Father’s age at death	1.5	2.1	4.9	0.7	1.8	1.4	0.6	1.0	0.9	1.6	2.0	2.2	1.3	1.8	1.9	-0.0	0.9	1.2	1.7	1.5	1.3	1.2
Arm fat-free mass (right)	1.5	7.6	18.1	0.9	1.7	1.6	2.4	2.5	3.5	2.4	2.4	1.9	2.9	3.1	4.3	3.7	3.5	2.5	2.6	2.5	2.1	3.7
Medication: Blood pressure	1.5	2.7	4.9	1.4	0.7	1.3	2.0	1.7	2.0	1.4	1.8	0.9	1.8	1.4	1.9	2.2	2.1	2.1	1.1	1.1	1.4	1.7
Arm predicted mass (right)	1.5	7.5	17.7	0.9	2.0	1.7	2.3	2.4	3.4	2.5	2.5	2.1	2.9	3.2	4.2	3.4	3.4	2.4	2.8	2.5	2.1	3.5
Osteoarthritis (self-reported)	1.5	2.0	5.2	2.3	0.0	1.2	1.8	1.9	2.1	0.9	0.8	0.0	1.4	0.3	0.2	2.0	1.6	1.9	-0.0	1.6	1.2	1.6
Hearing aid user	1.5	1.6	5.0	0.7	1.5	1.7	0.4	0.9	0.6	1.5	1.7	2.2	1.0	1.6	0.7	-1.0	0.4	1.2	1.7	1.6	1.4	0.8
Age started oral contraceptive pill	1.5	1.8	6.6	0.7	2.1	1.0	0.7	0.4	0.5	1.4	1.7	2.1	1.1	1.9	2.6	0.6	0.7	1.0	1.8	0.9	0.9	0.8
Arm predicted mass (left)	1.5	7.8	18.0	0.8	1.9	1.9	2.5	2.5	3.3	2.5	2.7	2.2	3.0	3.2	4.2	3.4	3.3	2.7	2.7	2.5	2.2	3.6
Crohns Disease (2017)	1.4	3.0	7.8	2.8	0.9	2.0	2.3	2.5	1.8	1.6	1.4	0.6	1.8	0.3	0.5	2.1	1.9	1.8	0.0	1.6	1.9	1.9
Bipolar Disorder (2011)	1.4	1.3	4.8	-0.9	2.0	0.8	-0.4	-0.4	-0.2	0.8	0.8	2.2	0.7	1.7	1.0	-1.5	-0.3	0.2	2.1	1.3	0.3	0.7
Systolic Blood Pressure	1.4	7.2	11.7	-3.4	-1.6	-2.4	-2.7	-3.1	-3.1	-2.6	-2.4	-1.7	-2.5	-2.2	-2.6	-3.3	-2.9	-2.8	-1.5	-2.8	-3.0	-3.1
Systolic blood pressure, automated reading	1.4	3.9	6.8	-2.3	-1.3	-1.8	-1.9	-2.5	-2.4	-1.9	-1.9	-1.2	-1.9	-1.4	-1.9	-2.2	-2.2	-1.8	-0.9	-2.4	-2.1	-2.6
Alcohol usually taken with meals	1.4	2.2	5.7	-2.0	-1.0	-1.1	-1.8	-1.6	-1.7	-1.3	-1.1	-0.7	-1.1	-1.1	-1.6	-2.4	-1.5	-1.9	-0.7	-1.2	-1.7	-1.4
Medication: Ibuprofen (e.g. Nurofen)	1.4	1.7	4.2	-0.1	-1.0	-1.1	-1.4	-0.8	-1.1	-1.4	-1.6	-1.3	-1.5	-1.7	-2.0	-1.5	-1.4	-1.0	-1.7	-1.0	-1.3	-0.8
Hypothyroidism/myxoedema (self-reported)	1.4	2.7	5.1	-1.1	-0.9	-1.5	-1.2	-1.3	-1.8	-1.7	-1.7	-1.9	-1.4	-2.2	-2.1	-1.0	-1.4	-1.4	-2.1	-2.0	-1.8	-1.9
Number of children fathered	1.4	1.6	3.8	-1.3	-0.2	-0.9	-1.4	-1.7	-1.8	-1.2	-0.9	-0.3	-1.4	-0.8	-0.8	-1.7	-2.0	-1.0	-0.6	-1.0	-1.1	-1.9
Eye problems/disorders: None of the above	1.4	1.6	3.5	1.4	0.7	1.2	1.4	1.5	1.8	1.3	1.0	0.7	1.5	0.9	0.8	0.9	1.8	0.3	1.0	1.4	1.0	1.9
Qualifications: NVQ or HND or HNC or equivalent	1.4	1.6	3.0	-1.5	-0.8	-1.3	-1.1	-1.5	-1.5	-1.3	-1.4	-1.0	-1.4	-1.1	-1.0	-0.9	-1.4	-0.9	-1.0	-1.7	-1.4	-1.6
Illnesses of father: Heart disease	1.4	1.9	3.7	-0.8	-1.9	-1.2	-0.7	-0.8	-1.2	-1.3	-1.5	-1.8	-1.1	-1.9	-1.9	-0.4	-0.9	-1.2	-1.8	-1.7	-1.2	-1.3
Illnesses of father: None of the above (group 1)	1.4	1.8	3.7	-0.9	-0.7	-1.5	-1.6	-1.7	-1.5	-1.4	-1.2	-0.9	-1.7	-0.8	-0.8	-1.1	-1.7	-1.3	-0.8	-1.4	-1.2	-1.9
Unable to work because of sickness or disability	1.4	1.8	3.8	0.4	0.5	1.4	1.0	1.3	1.3	1.5	1.3	1.8	1.3	1.5	1.3	0.8	0.9	1.7	1.3	2.0	1.4	1.5
Ever had hysterectomy (womb removed)	1.3	1.5	3.1	1.0	1.8	1.6	1.4	0.6	0.4	1.4	1.5	1.7	1.8	1.2	0.7	-0.1	1.0	0.9	1.8	0.7	0.9	0.7
Fluid intelligence score	1.3	2.7	9.0	1.2	3.0	1.7	1.0	1.0	1.0	1.6	1.7	2.3	1.8	1.8	1.9	0.2	1.0	1.1	1.8	1.8	1.1	1.6
Verbal and Numeric Reasoning (VNR)	1.2	2.9	5.1	2.1	2.0	1.8	1.3	1.3	1.3	1.7	1.8	2.3	1.8	1.9	1.9	0.5	1.2	1.4	1.9	2.1	1.4	1.8
Rheumatoid Arthritis	1.2	1.7	4.4	1.1	1.1	2.1	0.9	1.5	0.6	1.5	1.8	1.9	1.3	0.7	0.2	-0.5	0.4	1.7	0.5	1.9	1.5	1.0
Vitamin and mineral supplements	1.2	1.6	3.6	1.8	0.9	1.1	1.6	1.5	1.6	1.1	0.8	0.3	1.2	0.9	0.8	1.9	1.5	1.2	0.7	1.1	1.4	1.3
Medication: Simvastatin	1.2	1.7	4.0	0.2	0.7	1.1	1.6	1.0	1.2	1.2	1.4	1.1	1.6	1.3	1.9	2.0	1.5	1.7	1.1	0.8	1.0	1.0
Serious illness, injury or assault of a close relative in last 2 years	1.2	1.4	2.5	-1.5	-1.4	-1.5	-1.4	-0.9	-0.6	-1.4	-1.2	-1.3	-1.1	-1.1	-0.8	-0.7	-0.7	-1.6	-1.1	-0.8	-1.5	-0.5
High blood pressure (siblings)	1.2	1.7	4.3	0.4	1.3	0.6	0.7	1.6	2.1	1.0	1.0	0.5	1.4	1.1	1.0	1.4	1.8	0.7	0.8	2.1	0.9	2.1
Medication: Allopurinol	1.2	1.5	4.2	1.0	0.7	1.5	1.7	1.4	1.0	1.3	1.3	1.0	1.3	0.8	1.1	1.5	1.1	2.0	0.6	0.8	1.4	1.0
Height	1.1	20.8	57.6	4.3	3.0	6.2	5.6	5.5	3.4	4.7	5.5	4.3	4.7	2.5	3.1	3.6	3.4	7.6	1.5	4.0	5.5	4.1
Hypothyroidism (self reported)	1.1	2.6	5.1	-1.1	-1.1	-1.6	-1.3	-1.2	-1.5	-1.8	-1.7	-2.0	-1.4	-2.2	-2.0	-0.8	-1.4	-1.4	-2.3	-1.6	-1.8	-1.6
Fed-up feelings	1.1	1.9	3.8	-1.6	-0.9	-1.7	-1.6	-1.4	-1.4	-1.6	-1.4	-1.5	-1.9	-1.1	-0.8	-0.3	-1.5	-0.9	-1.4	-1.8	-1.0	-1.7
Medication: Cholesterol lowering	1.1	1.8	6.7	0.8	0.5	0.8	1.8	1.3	1.5	1.1	1.3	0.5	1.5	0.9	1.8	2.6	1.7	1.6	0.6	0.8	0.9	1.2
Trunk predicted mass	1.1	6.2	13.7	0.7	1.5	1.7	1.9	2.6	3.2	2.2	2.5	2.0	2.7	2.5	3.5	2.7	3.1	2.3	1.9	2.8	1.8	3.7
Standing height	1.1	11.1	23.0	2.9	2.7	4.5	3.9	4.1	2.6	3.5	4.0	3.2	3.6	1.8	2.3	2.3	2.6	4.8	1.2	3.5	3.9	3.2
Leg pain on walking	1.1	1.4	4.0	-0.9	-2.0	-0.9	-0.3	-0.3	-0.8	-1.0	-0.7	-1.6	-0.8	-1.8	-1.4	0.2	-0.4	-0.3	-2.0	-1.8	-1.1	-1.2
Medication: Laxatives (e.g. Dulcolax, Senokot)	1.1	1.3	2.9	0.5	0.8	0.9	0.9	1.4	1.7	0.9	1.5	0.6	1.2	0.9	1.2	1.1	1.5	1.2	0.5	1.0	0.9	1.6
Schizophrenia (2014)	1.0	2.1	3.6	1.5	1.6	1.3	1.7	1.5	1.6	1.5	1.0	0.9	1.9	1.1	1.2	1.6	1.8	1.0	1.1	1.6	1.2	1.9
Ulcerative Colitis	1.0	1.4	2.9	1.7	1.4	1.7	1.5	1.4	0.7	1.4	1.3	1.3	1.2	0.6	0.6	0.5	0.9	1.4	0.7	0.7	1.4	1.1
Lung FEV1/FVC ratio	1.0	5.2	28.2	-5.3	1.1	-3.3	-3.4	-3.1	-1.5	-1.6	-1.9	-0.6	-1.9	0.9	0.9	-1.4	-1.4	-3.3	1.1	-1.0	-2.3	-1.5
Trunk fat-free mass	1.0	6.0	13.3	0.6	1.4	1.6	1.9	2.5	3.2	2.1	2.4	1.9	2.6	2.5	3.5	2.7	3.0	2.2	1.9	2.7	1.8	3.6
Mouth/teeth dental problems: Dentures	1.0	1.6	5.7	0.6	2.4	1.6	1.2	1.0	0.5	1.4	1.7	1.8	1.4	1.0	1.2	0.3	0.6	1.7	1.0	1.1	1.1	0.7
Forced expiratory volume in 1-second (FEV1), Best measure	1.0	3.3	7.4	2.5	1.3	2.2	2.7	2.3	1.9	1.8	1.4	0.8	2.1	0.7	0.6	2.0	2.0	2.2	0.6	1.6	2.0	1.9
Tinnitus: Yes, now most or all of the time	1.0	1.1	3.2	0.8	1.1	1.8	1.0	1.0	0.3	1.3	1.3	1.7	1.4	0.7	0.0	-0.8	0.7	0.8	1.1	1.0	0.9	1.0
Medication: Blood pressure	1.0	1.8	3.4	1.9	1.6	1.4	1.6	1.1	1.2	1.5	1.4	1.2	1.4	1.3	1.0	1.0	1.5	1.3	1.5	0.5	1.4	1.0
Impedance of arm (right)	0.9	4.2	12.7	3.4	1.4	3.5	2.8	2.5	0.2	2.0	2.2	1.4	1.5	-0.3	-1.1	0.6	0.4	3.6	-0.6	1.1	3.0	0.1
Prospective memory result	0.9	1.1	2.6	-1.3	-1.2	-1.2	-1.1	-0.5	-0.3	-1.2	-1.0	-1.5	-1.2	-1.3	-1.4	-0.2	-0.8	-0.6	-1.6	-0.4	-0.9	-0.9
Seen doctor (GP) for nerves, anxiety, tension or depression	0.9	1.4	7.1	1.1	-0.6	0.1	1.2	1.2	2.0	0.4	0.2	-0.7	0.8	0.8	0.9	2.7	1.7	0.9	0.4	1.0	0.9	1.3
Ever highly irritable/argumentative for 2 days	0.9	1.1	2.1	-1.4	-0.3	-1.0	-0.8	-1.2	-1.1	-1.2	-1.4	-1.0	-1.2	-0.9	-1.2	-0.8	-1.3	-0.8	-0.7	-0.8	-0.9	-1.2
Health satisfaction	0.9	1.2	2.4	1.3	0.6	1.1	1.1	0.8	1.3	1.0	0.8	1.0	1.0	1.4	0.7	0.7	1.0	1.4	1.6	0.9	1.1	1.2
Mouth/teeth dental problems: Loose teeth	0.9	1.1	2.5	-0.5	-0.7	0.7	0.8	1.1	1.4	0.9	1.1	0.8	1.0	1.1	1.6	1.3	1.2	0.8	0.8	1.4	0.9	1.4
Neck or shoulder pain in last month	0.9	1.2	4.6	-1.3	-0.1	-0.7	-1.6	-1.3	-1.1	-1.0	-1.1	-0.0	-1.0	-0.4	-1.5	-2.1	-1.6	-0.9	-0.2	0.4	-1.1	-0.8
Miserableness	0.9	1.5	4.7	-2.2	0.3	-0.9	-1.9	-1.6	-1.6	-0.8	-0.4	0.5	-1.4	0.1	0.0	-2.2	-1.7	-0.9	0.2	-1.1	-0.9	-1.2
Ever used hormone-replacement therapy (HRT)	0.8	1.1	4.3	0.2	1.0	1.3	0.2	0.2	-0.0	1.1	1.2	2.1	0.6	1.5	0.6	-1.1	-0.3	0.9	1.7	1.2	1.1	0.2
Ever unenthusiastic/disinterested for a whole week	0.8	1.0	8.1	0.6	-1.0	-0.6	0.9	0.5	1.1	-0.4	-0.4	-1.5	-0.4	-0.4	0.8	2.8	0.7	1.1	-1.1	-0.6	0.3	0.2
Financial difficulties in last 2 years	0.8	1.1	2.9	0.8	1.2	0.7	1.1	1.2	1.4	0.8	1.0	0.2	0.8	0.8	1.1	1.7	1.4	1.4	0.6	0.3	1.1	1.1
Breastfed as a baby	0.8	1.0	1.9	0.9	1.1	1.3	1.1	0.9	0.5	1.2	1.4	1.4	1.1	0.9	1.1	0.5	0.8	0.9	1.0	0.6	1.1	0.7
Commuting to job workplace: Public transport	0.8	1.0	2.9	-0.8	-1.4	-1.4	-1.0	-0.4	0.1	-1.3	-1.3	-1.7	-1.1	-1.0	-0.6	0.3	-0.3	-0.7	-1.3	-0.7	-0.9	-0.1
High cholesterol (Self-reported)	0.8	1.5	6.0	0.4	0.5	0.8	1.8	1.5	1.6	0.8	1.1	-0.1	1.5	0.2	1.2	2.4	1.9	1.5	-0.1	0.1	0.6	1.2
Alcohol drinker status: Never	0.8	1.0	3.8	-0.9	0.8	0.7	-0.1	-0.1	-0.0	1.0	1.3	1.8	0.9	1.5	1.4	-0.9	0.4	-0.5	1.9	0.8	0.3	0.3
Ever had prostate specific antigen (PSA) test	0.8	1.0	2.6	0.6	-0.1	0.9	1.2	1.4	1.4	1.0	0.7	0.2	1.4	0.3	0.3	1.1	1.6	0.4	0.3	1.1	0.7	1.5
Intelligence (Savage-Jansen 2018)	0.7	2.3	4.0	2.0	0.8	1.9	1.6	1.7	1.3	1.6	1.6	1.5	2.0	1.0	1.1	0.9	1.4	1.3	1.0	2.0	1.3	1.7
Lupus	0.7	1.0	2.5	-0.8	-1.6	-1.0	-0.6	-0.5	-0.6	-1.0	-1.4	-1.5	-0.9	-1.5	-1.2	0.1	-0.6	-1.0	-1.5	-0.8	-0.9	-0.6
Blood Red Count	0.7	7.0	15.1	0.6	3.6	2.9	3.1	1.6	1.6	2.9	2.6	2.9	3.7	3.2	2.3	1.6	2.7	2.3	3.9	1.8	2.3	2.2
Number of incorrect matches in round	0.7	1.2	3.5	-0.3	1.9	1.2	0.7	0.4	0.3	1.1	1.3	1.7	1.4	1.4	1.2	-0.2	0.7	0.4	1.7	0.9	0.7	0.8
Diabetes (self-reported)	0.7	1.1	2.8	0.2	1.0	0.5	0.8	0.7	1.3	0.9	1.0	0.8	0.9	1.4	1.7	1.4	1.2	1.2	1.2	0.7	0.9	1.0
Impedance of arm (left)	0.7	3.2	10.5	3.2	1.0	3.1	2.5	2.0	-0.1	1.6	1.7	1.0	1.1	-0.6	-1.4	0.4	0.0	3.2	-0.8	0.7	2.6	-0.4
Tense / ‘highly strung’	0.7	1.1	1.9	-1.2	-0.6	-1.1	-1.3	-1.0	-0.9	-1.1	-1.1	-0.9	-1.4	-0.8	-1.3	-1.1	-1.2	-0.7	-0.8	-0.9	-0.8	-1.1
Loud music exposure frequency	0.7	0.7	2.8	-0.4	0.9	0.7	-0.1	-0.6	-0.6	0.5	0.5	1.7	0.1	1.2	0.4	-1.5	-0.8	0.6	1.6	0.4	0.4	-0.3
Age at last live birth	0.7	1.0	1.6	-0.4	-0.8	-1.3	-1.0	-0.9	-0.6	-1.2	-1.0	-1.3	-1.3	-0.9	-0.9	-0.5	-0.9	-0.7	-1.1	-1.1	-0.9	-1.1
Eye problems/disorders: Cataract	0.7	0.8	2.5	-1.6	-0.3	-0.8	-1.4	-1.3	-1.4	-0.8	-0.4	0.0	-0.8	-0.1	-0.0	-1.0	-1.3	-0.6	-0.2	-0.4	-0.8	-1.2
Heart disease (siblings)	0.7	0.8	2.3	-1.2	-0.8	-1.5	-1.5	-0.8	-0.4	-1.0	-0.9	-0.9	-1.2	-0.5	-0.5	-0.5	-0.7	-0.9	-0.8	-0.5	-1.0	-0.7
Major Depression (MDD)	0.6	0.7	3.2	-0.1	0.8	1.1	0.2	0.8	0.7	0.7	0.9	1.2	0.8	0.8	0.2	-0.4	0.3	0.6	0.7	1.8	0.8	1.1
HDL Cholesterol	0.6	0.9	3.9	-0.3	-1.6	-0.4	-0.5	0.1	-0.3	-0.9	-0.7	-1.2	-1.0	-1.6	-1.6	-0.5	-0.9	0.0	-2.0	-0.1	-0.3	-0.5
Medication for hormone replacement therapy	0.6	0.7	2.7	0.1	1.3	1.1	-0.1	0.3	-0.3	1.0	1.2	1.6	0.5	0.7	0.3	-1.2	-0.1	0.2	0.9	0.6	0.7	-0.1
Diabetes (mother)	0.6	0.8	3.3	-1.8	0.4	-0.7	-1.3	-1.4	-0.9	-0.6	-0.2	0.4	-0.9	0.6	0.4	-1.4	-1.1	-0.6	0.7	-0.6	-0.6	-1.0
Hayfever/allergic rhinitis (self-reported)	0.6	0.8	3.0	1.7	-0.5	1.0	0.8	1.1	-0.1	0.2	0.5	-0.4	0.2	-1.1	-1.4	0.2	0.0	1.3	-1.4	-0.2	0.8	-0.2
Number of full sisters	0.6	0.8	2.2	0.8	-0.3	0.6	1.0	0.9	1.2	0.8	0.4	0.3	0.4	1.0	0.8	1.5	0.8	1.1	0.8	0.9	1.3	0.8
Ever had bowel cancer screening	0.6	0.6	2.0	-0.1	0.1	0.7	0.7	1.0	1.0	0.7	0.8	0.6	1.1	0.6	0.6	0.6	1.1	0.3	0.6	1.4	0.5	1.3
Diabetes diagnosed by doctor	0.6	1.0	3.0	0.1	1.0	0.5	0.9	0.7	1.2	0.8	1.1	0.6	0.9	1.3	1.7	1.5	1.2	1.4	1.0	0.3	0.9	0.7
Average weekly champagne plus white wine intake	0.6	0.8	3.0	0.4	1.7	0.7	0.3	0.2	0.4	0.8	1.0	1.3	0.8	1.3	1.0	-0.2	0.5	0.4	1.4	0.9	0.6	0.6
Myopia	0.6	0.8	2.0	0.3	1.1	1.4	0.9	0.6	0.2	1.2	1.3	1.3	1.4	0.8	0.1	-0.6	0.9	0.0	1.3	0.4	0.6	0.4
LDL Cholesterol	0.5	0.8	2.5	1.6	-0.4	0.9	1.1	1.4	0.9	0.7	0.7	-0.0	0.7	-0.2	0.0	1.3	1.1	1.0	-0.3	-0.1	0.9	0.8
Frequency of depressed mood in last 2 weeks	0.5	0.7	2.2	-0.9	0.6	-0.6	-1.3	-1.0	-1.0	-0.5	-0.5	0.3	-0.9	0.1	-0.3	-1.5	-1.1	-0.8	0.3	-0.6	-0.5	-0.8
Severe depression (siblings)	0.5	0.6	2.2	-0.2	-0.6	0.5	0.3	1.5	0.8	0.4	0.2	-0.5	0.5	-0.9	-0.7	0.3	0.9	-0.2	-1.2	0.8	0.3	1.3
Medication: Atenolol	0.5	0.6	3.0	0.7	0.6	-0.0	0.7	0.8	1.4	0.3	0.5	-0.2	0.1	0.5	1.3	1.7	1.0	0.9	-0.0	0.2	0.7	0.7
Sitting height	0.5	3.6	7.0	0.9	2.6	2.2	2.2	1.9	1.4	2.0	2.0	1.9	2.2	1.4	2.2	1.8	1.7	2.0	1.2	1.9	1.9	1.9
Hearing difficulty/problems with background noise	0.5	0.9	1.8	0.1	1.3	1.1	0.6	0.9	0.9	0.8	1.2	1.2	1.2	0.8	0.6	-0.3	0.7	0.9	0.9	1.2	0.5	1.4
Mouth/teeth dental problems	0.5	0.8	1.9	-0.1	-1.4	-1.3	-0.8	-1.2	-0.6	-1.0	-1.0	-1.1	-1.2	-0.4	-0.2	0.0	-0.7	-0.9	-0.4	-1.1	-0.8	-1.2
Noisy workplace	0.5	0.7	2.2	0.4	0.3	1.1	1.0	1.2	0.9	0.7	1.0	0.6	0.7	0.4	0.5	0.7	0.7	1.5	0.2	0.5	1.0	0.9
Illnesses of mother	0.5	0.7	1.9	0.4	-0.3	0.8	0.2	0.5	0.6	0.7	0.8	1.2	0.5	1.2	1.2	0.2	0.2	0.8	1.1	1.4	0.9	0.9
Blood clot in the leg (DVT)	0.5	0.6	1.7	-0.0	0.2	0.8	0.7	0.6	0.5	0.9	0.9	1.1	0.5	1.0	1.1	0.7	0.3	1.3	0.7	0.8	1.1	0.4
Exposure to tobacco smoke outside home	0.5	0.6	2.6	-0.3	-1.6	-0.3	-0.1	-0.3	-0.6	-0.6	-0.7	-0.9	-0.8	-1.0	-1.3	-0.2	-0.6	0.0	-1.0	-1.1	-0.3	-0.8
Shortness of breath walking on level ground	0.5	0.6	2.4	1.3	0.6	1.2	1.0	0.7	0.3	0.7	0.7	0.6	0.7	0.5	-0.4	0.2	0.3	1.5	0.6	0.3	1.0	0.2
Heart disease (mother)	0.5	0.6	1.6	-0.2	-0.1	-0.7	-0.3	-0.3	-0.4	-0.7	-0.9	-1.2	-0.6	-1.2	-1.1	-0.1	-0.3	-0.7	-1.2	-1.0	-0.8	-0.5
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.5	0.6	1.3	0.6	0.6	0.9	0.6	0.8	0.9	0.7	1.1	0.8	0.4	0.7	0.4	0.2	0.4	1.2	0.5	1.0	1.1	0.4
Back pain experienced in last month	0.5	0.7	2.4	-0.1	0.8	0.9	-0.4	0.5	0.3	0.7	0.8	1.5	0.6	0.9	0.2	-1.4	0.1	-0.0	1.2	1.3	0.5	1.2
Smoking status: Current	0.5	0.7	2.0	1.4	-0.2	0.8	1.4	1.3	1.0	0.7	0.3	-0.2	1.0	-0.2	-0.1	1.2	1.3	0.5	-0.2	0.3	0.7	1.1
Financial situation satisfaction	0.5	0.7	2.2	-0.1	-0.8	-0.8	-0.4	-0.3	-0.3	-1.0	-0.8	-1.5	-0.9	-1.0	-1.3	-0.0	-0.5	-0.1	-1.2	-1.0	-0.5	-0.8
Cholesterol lowering medication	0.5	0.7	2.2	0.6	0.4	0.9	1.2	0.7	0.7	0.7	0.9	0.7	0.9	0.6	1.0	1.2	0.7	1.5	0.6	0.2	0.8	0.7
Supplements: Calcium	0.5	0.5	2.5	0.8	1.0	1.0	1.0	0.6	0.3	0.7	0.9	0.7	0.6	0.4	0.5	0.6	0.3	1.6	0.2	0.1	0.9	0.1
Basal cell carcinoma (self-reported)	0.5	0.5	2.2	0.7	-0.6	-0.7	-0.2	-0.5	-0.8	-0.8	-0.6	-0.9	-0.6	-1.0	-0.3	0.2	-0.5	-0.1	-1.0	-1.5	-0.8	-0.7
Impedance of whole body	0.5	2.5	8.2	2.9	1.4	2.8	2.1	1.5	-0.7	1.2	1.3	0.9	0.7	-0.9	-1.8	-0.2	-0.6	2.7	-0.9	0.4	2.3	-0.9
Depressed Affect (Nagel 2018)	0.4	0.9	3.5	-1.4	1.1	-0.3	-1.5	-1.1	-1.3	-0.3	-0.0	0.9	-0.9	0.5	0.4	-1.9	-1.4	-0.6	0.6	-0.3	-0.3	-0.8
Schizophrenia (2018)	0.4	0.8	1.9	1.3	0.8	0.6	1.1	1.1	1.1	0.9	0.5	0.3	1.0	0.5	0.8	1.4	1.3	0.7	0.4	0.8	0.7	1.2
Alzheimer’s Disease (in mother)	0.4	0.4	1.3	-0.5	-0.7	-0.9	-0.5	-0.1	0.0	-0.6	-0.5	-1.0	-0.5	-0.9	-0.0	0.5	0.1	-0.9	-1.2	-0.7	-0.8	-0.0
Prostate Cancer	0.4	0.6	1.9	-0.0	1.4	0.7	0.5	0.0	0.1	0.9	0.6	1.3	0.7	1.1	1.1	0.1	0.2	0.2	1.3	0.8	0.5	0.3
Mean Putamen Volume	0.4	0.4	1.3	-0.8	-0.8	-0.3	-0.7	-0.5	-0.9	-0.3	-0.1	-0.1	-0.3	-0.5	-0.7	-1.1	-0.4	-0.6	-0.3	-1.1	-0.6	-0.7
Neuroticism (2016)	0.4	0.6	1.5	-1.2	0.4	-0.7	-1.2	-1.1	-1.0	-0.6	-0.4	0.2	-1.0	0.2	0.2	-0.9	-1.1	-0.5	0.2	-0.6	-0.5	-0.9
Type 2 Diabetes (T2D) (2012)	0.4	0.5	1.6	0.4	1.0	0.6	0.5	0.2	0.5	0.5	0.2	0.8	0.9	0.8	0.3	-0.1	0.5	0.1	1.2	1.3	0.3	0.8
Medication: Co-codamol	0.4	0.4	1.3	0.2	-0.8	0.1	0.1	-0.2	-0.9	-0.5	-0.5	-0.4	-0.6	-1.0	-1.1	-0.2	-0.9	0.5	-1.0	-0.9	-0.2	-0.9
Frequency of unenthusiasm / disinterest in last 2 weeks	0.4	0.5	1.2	-0.8	-0.2	-0.6	-1.1	-0.9	-0.8	-0.6	-0.6	0.1	-1.0	0.0	-0.2	-1.1	-1.0	-0.5	0.1	-0.7	-0.5	-0.7
Supplements: Glucosamine	0.4	0.5	1.3	0.2	-0.3	-0.5	-0.5	-0.4	-0.7	-0.8	-0.5	-0.8	-0.4	-1.1	-0.9	-0.7	-0.5	-0.5	-1.1	-0.8	-1.0	-0.5
Had other major operations	0.4	0.5	1.8	0.6	-0.4	-0.5	-0.2	0.1	0.2	-0.8	-0.6	-1.3	-0.3	-1.2	-1.3	-0.0	-0.0	0.1	-1.3	-0.4	-0.7	-0.1
Gout (self-reported)	0.4	0.6	1.1	0.4	0.7	1.0	1.0	0.4	0.2	0.9	1.1	1.1	0.9	0.8	0.9	0.4	0.5	1.1	0.9	0.2	0.7	0.3
Chest pain or discomfort	0.4	0.6	1.9	0.4	-0.1	1.3	1.2	1.4	0.2	0.7	0.6	0.1	1.2	-0.8	-1.1	0.1	0.8	0.6	-0.6	0.1	0.5	0.9
Family relationship satisfaction	0.4	0.5	1.7	0.5	0.7	0.8	0.6	1.3	1.0	0.6	0.9	0.1	0.9	0.0	-0.2	0.1	1.1	0.5	-0.0	0.5	0.6	1.3
Knee pain experienced in last month	0.4	0.7	1.6	1.0	-0.8	0.8	1.1	0.9	0.9	0.6	0.6	0.5	0.5	0.6	0.7	1.1	0.7	1.3	0.5	0.6	0.9	0.8
Medication: Aspirin	0.4	0.5	2.0	0.5	-0.9	-0.6	0.4	-0.0	0.1	-0.7	-0.3	-1.4	-0.3	-1.0	-0.4	1.0	0.3	0.2	-1.2	-1.3	-0.5	-0.5
Medication: Gliclazide	0.4	0.5	1.9	0.1	0.0	0.1	0.4	1.0	1.4	0.1	0.2	-0.4	0.4	0.1	0.3	1.2	0.9	0.8	-0.4	1.0	0.4	1.1
Irritability	0.4	0.6	1.7	1.2	1.1	0.4	0.8	0.8	1.0	0.6	0.5	0.0	0.4	0.6	0.6	1.3	0.9	1.2	0.4	-0.0	0.9	0.6
Alzheimer’s Disease (including proxy)	0.3	0.5	2.0	1.2	-0.3	0.0	0.6	1.0	1.2	0.3	0.3	-0.4	0.2	-0.3	0.7	1.4	0.9	0.3	-0.7	0.3	0.4	0.9
Fasting Glucose	0.3	0.4	1.1	-0.9	-1.0	-0.4	-0.2	-0.4	-0.5	-0.8	-0.3	-0.8	-0.3	-0.8	-0.7	-0.2	-0.4	-0.1	-0.9	-0.8	-0.7	-0.6
Type 2 Diabetes (T2D) (2018)	0.3	0.5	2.3	-0.2	0.4	-0.2	0.3	0.7	1.2	0.3	0.6	-0.2	0.5	0.5	1.2	1.5	1.2	0.4	0.1	0.1	0.2	0.8
Average weekly spirits intake	0.3	0.4	2.0	-0.6	-0.4	0.1	-0.9	-0.6	-0.8	0.2	0.2	1.0	-0.3	0.6	0.1	-1.4	-0.9	-0.4	0.7	0.7	0.2	-0.5
Impedance of leg (right)	0.3	1.4	4.5	1.4	1.3	1.5	0.7	0.3	-1.4	0.2	0.4	0.4	-0.5	-1.3	-2.1	-1.2	-1.5	1.6	-1.3	-0.4	1.1	-1.6
Stomach or abdominal pain in last month	0.3	0.4	1.8	-0.0	0.0	0.1	0.1	0.9	1.0	-0.1	-0.4	-0.6	0.1	-0.3	-0.8	0.8	0.4	0.5	-0.6	1.3	0.4	0.9
Impedance of leg (left)	0.3	1.4	5.0	1.2	1.2	1.5	0.6	0.2	-1.6	0.2	0.3	0.4	-0.5	-1.2	-2.2	-1.4	-1.6	1.4	-1.2	-0.3	1.0	-1.7
Pulse rate	0.3	0.5	2.9	0.8	1.7	0.9	0.4	0.4	0.2	0.6	0.3	0.8	0.9	0.4	-0.4	-0.8	0.3	0.1	0.8	1.0	0.2	0.7
Number of full brothers	0.3	0.4	1.3	0.8	0.2	0.0	0.4	1.1	1.1	0.2	0.2	-0.8	0.5	-0.3	-0.4	1.0	1.1	0.0	-0.6	0.5	0.2	0.8
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.3	0.4	1.0	-0.8	-0.2	-0.6	-0.7	-1.0	-0.5	-0.5	-0.5	0.2	-1.0	0.4	0.7	-0.3	-1.0	-0.1	0.3	-0.4	-0.3	-0.7
Medication: Aspirin	0.3	0.4	1.7	0.1	-0.5	-0.8	0.1	-0.2	0.0	-0.7	-0.4	-1.3	-0.4	-0.9	-0.4	0.8	0.1	-0.1	-1.0	-1.3	-0.7	-0.6
Mouth/teeth dental problems: Mouth ulcers	0.3	0.5	1.5	-1.2	-0.6	-0.5	-0.8	-0.5	-0.7	-0.7	-0.4	-0.5	-0.7	-0.8	-0.6	-0.9	-0.7	-0.5	-0.8	-0.8	-0.7	-0.5
Wears glasses or contact lenses	0.3	0.3	1.6	-1.2	0.6	0.2	-0.5	-0.5	-0.7	0.1	0.3	0.6	-0.0	0.1	-0.4	-1.3	-0.6	-0.1	0.3	-0.0	-0.2	-0.7
Ever taken oral contraceptive pill	0.3	0.3	1.1	-0.8	0.0	-0.5	-0.4	-0.9	-0.9	-0.4	-0.4	-0.1	-0.8	-0.1	0.4	-0.1	-0.8	-0.4	-0.1	-1.1	-0.3	-1.0
Medication: Atorvastatin	0.3	0.4	1.3	0.9	-0.2	0.2	1.1	0.5	0.2	0.0	0.1	-0.7	0.3	-0.8	-0.5	1.1	0.5	0.7	-0.8	-0.8	0.1	-0.2
Risk taking	0.3	0.5	3.3	-0.0	0.5	0.7	1.0	0.6	0.6	0.4	0.8	0.3	0.5	0.4	0.4	0.6	0.5	1.8	0.2	-0.3	0.7	0.4
Ever depressed for a whole week	0.3	0.4	2.5	-0.3	-0.7	-0.3	0.4	0.4	1.1	-0.3	0.1	-0.7	0.2	0.2	0.9	1.6	0.8	0.6	-0.2	0.1	0.1	0.8
Commuting to job workplace: Cycle	0.3	0.4	1.9	0.3	-0.7	0.1	0.5	1.0	0.8	0.3	0.4	-0.3	0.1	-0.3	0.6	1.4	0.7	0.5	-0.8	0.2	0.5	0.6
Pain experienced in last month	0.3	0.6	2.4	1.0	0.6	0.2	1.1	0.7	0.9	0.7	0.4	-0.3	0.8	0.3	0.7	1.6	1.4	0.2	0.2	-0.0	0.5	0.5
Deep venous thrombosis (DVT) (self-reported)	0.3	0.4	1.3	-0.2	0.0	0.7	0.6	0.4	0.2	0.8	0.8	1.0	0.3	0.8	0.8	0.4	0.1	1.1	0.6	0.5	0.9	0.1
Pack years of smoking	0.3	0.4	1.5	0.0	1.2	0.6	0.1	-0.3	-0.4	0.4	1.0	1.1	0.4	0.8	0.8	-0.7	-0.2	0.6	0.9	-0.3	0.2	-0.3
Coronary Artery Disease (CAD)	0.2	0.2	0.9	-0.7	-0.2	0.1	0.4	-0.3	-0.1	0.3	0.3	0.5	0.3	0.8	0.9	0.7	0.1	0.2	0.9	-0.5	0.2	-0.3
Triglycerides	0.2	0.3	1.4	0.1	1.2	0.4	0.5	-0.0	-0.2	0.5	0.1	0.5	1.0	0.4	0.1	-0.1	0.5	-0.4	0.9	0.1	-0.1	0.3
Blood Platelet Count	0.2	2.5	7.6	1.8	-0.1	0.9	1.2	2.3	2.8	1.0	1.3	0.2	1.2	0.7	1.4	2.2	2.1	1.4	-0.1	1.9	1.2	2.6
Chronotype (morning person)	0.2	0.5	2.0	0.7	0.2	0.5	0.9	1.1	1.0	0.4	0.6	-0.4	1.1	-0.2	-0.1	0.9	1.4	0.2	-0.2	0.3	0.1	1.0
Hand grip strength (left)	0.2	0.6	2.9	-0.1	0.1	-0.4	-0.0	0.4	1.5	0.0	-0.3	-0.1	0.1	0.8	1.2	1.1	0.7	0.1	0.4	1.7	0.2	1.5
Eye problems/disorders: Diabetes related eye disease	0.2	0.2	0.7	-0.1	-0.5	-0.6	-0.1	0.2	0.5	-0.3	0.0	-0.8	-0.2	-0.4	0.2	0.9	0.6	-0.0	-0.7	-0.7	-0.4	0.1
Angina	0.2	0.3	1.3	-0.2	-1.1	-0.5	0.1	0.2	0.6	-0.4	-0.4	-0.7	-0.0	-0.2	0.3	1.1	0.3	0.1	-0.5	0.2	-0.3	0.5
Hand grip strength (right)	0.2	0.4	1.4	-0.3	-0.3	-0.8	-0.1	0.1	1.1	-0.3	-0.8	-0.6	-0.2	0.3	0.9	1.2	0.4	-0.5	-0.0	1.1	-0.2	0.9
Current tobacco smoking	0.2	0.3	0.8	0.7	-0.8	-0.0	0.5	0.6	0.4	-0.1	-0.4	-0.9	0.1	-0.9	-0.6	0.6	0.6	-0.2	-0.9	-0.3	-0.1	0.4
Tinnitus: Yes, but not now, but have in the past	0.2	0.2	0.5	0.3	-0.0	0.3	0.4	0.2	0.6	0.3	0.3	0.3	0.2	0.7	0.5	0.5	0.2	0.6	0.6	0.4	0.5	0.2
Qualifications: CSEs or equivalent	0.2	0.3	2.0	1.4	-0.3	0.1	0.1	0.3	-0.1	-0.2	-0.6	-0.7	-0.3	-0.8	-1.4	-0.1	-0.1	0.0	-0.7	-0.1	0.1	-0.1
Had menopause	0.2	0.3	0.8	-0.4	0.2	0.6	0.4	0.5	0.3	0.8	0.9	0.9	0.8	0.6	0.6	-0.0	0.5	0.2	0.5	0.8	0.4	0.3
Qualifications: None of the above	0.2	0.3	1.5	-0.0	0.1	0.8	0.8	0.4	0.0	0.7	0.6	0.7	0.3	0.6	0.2	0.4	0.1	1.2	0.6	0.0	1.0	-0.2
Hair/balding pattern: Pattern 3	0.2	0.3	1.3	0.3	0.2	-0.0	-0.1	0.8	1.1	0.3	0.5	-0.1	0.3	0.2	0.5	0.3	0.9	-0.3	-0.0	0.7	0.1	1.1
Number of live births	0.2	0.2	1.0	0.3	-0.2	-0.3	-0.7	-0.6	-0.6	-0.2	-0.3	0.2	-0.6	0.0	-0.2	-1.0	-0.9	-0.3	0.0	0.1	-0.2	-0.5
Happiness	0.2	0.2	0.6	0.6	0.7	0.2	0.2	0.3	0.7	0.2	0.1	0.2	0.2	0.6	0.4	0.4	0.4	0.5	0.6	0.3	0.4	0.8
Medication: Lansoprazole	0.2	0.3	0.8	0.1	0.2	0.5	0.1	-0.5	-0.6	0.2	0.4	0.9	-0.2	0.6	0.2	-0.8	-0.7	0.6	0.8	-0.3	0.3	-0.8
Peak expiratory flow (PEF)	0.2	0.5	1.6	-0.4	-0.7	-0.9	-0.6	-0.7	-0.2	-1.0	-1.3	-1.1	-0.7	-0.7	-1.0	-0.2	-0.6	-0.6	-0.7	-0.0	-0.8	-0.4
Qualifications: O levels/GCSEs or equivalent	0.2	0.4	1.2	-0.6	0.4	0.1	-0.8	-0.3	-0.2	0.2	0.5	1.1	0.1	0.8	1.0	-1.1	-0.3	-0.5	0.8	0.6	-0.1	0.4
Reason for reducing amount of alcohol drunk: Health precaution	0.2	0.3	0.8	0.5	0.7	0.9	0.4	0.7	0.2	0.4	0.4	0.4	0.4	-0.1	-0.9	-0.6	0.1	0.6	-0.1	0.6	0.6	0.4
Medication for pain relief, constipation, heartburn	0.2	0.3	1.2	-0.3	0.5	0.3	0.3	0.1	0.2	0.7	0.1	0.8	0.5	0.9	1.1	0.5	0.3	-0.2	1.0	0.9	0.5	0.5
Angina (self-reported)	0.2	0.2	1.2	-0.0	-1.0	-0.5	0.1	0.1	0.6	-0.4	-0.4	-0.7	-0.0	-0.2	0.4	1.1	0.4	0.0	-0.5	0.1	-0.4	0.5
Migraine (self-reported)	0.2	0.3	1.1	-0.2	-0.4	-0.5	-0.3	-0.4	-0.2	-0.6	-0.7	-0.7	-0.6	-0.5	-1.0	-0.4	-0.4	-0.3	-0.5	-0.5	-0.5	-0.5
Mean time to correctly identify matches	0.2	0.4	1.3	-0.4	1.1	0.7	0.0	-0.2	-0.5	0.7	0.4	1.1	0.5	0.7	-0.2	-1.1	-0.2	-0.2	1.1	0.7	0.4	-0.2
Alcohol intake frequency.	0.2	0.5	2.2	-0.3	1.4	0.3	-0.1	-0.4	-0.4	0.5	0.5	1.2	0.7	1.0	0.9	-0.7	0.1	-0.6	1.5	0.2	-0.1	0.2
Forced expiratory volume in 1-second (FEV1), predicted	0.2	0.4	2.1	0.6	-0.0	0.5	0.3	1.0	0.3	-0.0	-0.2	-0.5	0.0	-1.2	-1.0	-0.1	-0.0	0.5	-1.5	0.7	0.2	0.8
Medication for cholesterol	0.2	0.4	0.8	-0.5	-0.9	-0.7	-0.4	-0.5	-0.5	-0.7	-0.9	-0.8	-0.4	-0.7	-0.5	-0.1	-0.4	-0.9	-0.7	-0.2	-0.7	-0.3
Pain type(s) experienced in last month: Hip pain	0.2	0.2	0.6	0.4	0.5	0.8	0.6	0.7	0.1	0.6	0.8	0.6	0.8	0.0	0.1	0.2	0.4	0.6	0.0	0.4	0.3	0.4
Medication: Lisinopril	0.2	0.2	1.3	-0.4	-0.1	-0.4	-0.3	-0.8	-0.5	-0.3	0.2	0.1	-0.4	0.2	0.7	-0.3	-0.4	-0.0	0.3	-1.2	-0.4	-0.8
Illnesses of father: High blood pressure	0.2	0.3	1.9	-1.4	-0.3	-0.7	-0.8	-0.7	-0.0	-0.5	-0.5	0.0	-0.4	0.4	0.6	-0.2	-0.4	-0.6	0.4	0.4	-0.5	0.1
Schizophrenia vs Biploar Disorder	0.1	0.2	0.5	0.5	0.3	-0.4	-0.1	-0.6	-0.5	-0.3	-0.4	-0.4	-0.3	-0.3	-0.3	-0.1	-0.3	-0.4	-0.1	-0.7	-0.4	-0.7
Reaction Time	0.1	0.2	0.7	-0.6	0.6	0.0	-0.3	-0.4	-0.8	0.1	-0.5	0.1	-0.2	-0.2	-0.9	-0.7	-0.5	-0.7	0.1	-0.1	-0.0	-0.7
Ovarian Cancer	0.1	0.1	0.3	0.5	0.3	0.3	0.2	0.3	0.2	0.2	0.6	0.1	0.2	0.1	0.3	0.1	0.3	0.0	0.1	-0.1	0.4	0.0
HbA1C	0.1	0.2	0.8	-0.4	-0.6	-0.5	-0.1	0.1	0.5	-0.2	-0.3	-0.7	-0.1	-0.1	-0.0	0.9	0.4	-0.6	-0.2	0.0	-0.2	0.2
Blood White Count	0.1	0.9	6.6	0.4	-1.1	-0.8	0.7	-0.1	0.8	-0.4	-0.2	-1.0	0.0	0.5	1.6	2.6	0.9	0.8	0.2	-1.3	-0.1	0.2
Tanning	0.1	1.1	2.7	-1.4	-1.6	-1.1	-0.8	-0.9	-0.7	-1.1	-1.1	-1.2	-1.1	-1.0	-1.1	-0.4	-0.9	-0.5	-1.1	-0.8	-1.0	-1.0
Relative age of first facial hair	0.1	0.3	1.4	0.6	-0.3	0.5	-0.0	0.6	0.6	0.4	0.4	0.5	0.1	0.5	0.0	-0.0	0.1	0.7	0.2	1.2	0.7	0.5
Pack years adult smoking proportion	0.1	0.2	0.7	-0.3	0.3	-0.1	-0.4	-0.5	-0.7	-0.3	0.2	0.2	-0.2	-0.1	0.1	-0.8	-0.5	0.1	-0.0	-0.8	-0.4	-0.6
Bilateral oophorectomy (both ovaries removed)	0.1	0.1	0.6	-0.3	0.1	-0.1	-0.5	-0.3	-0.3	-0.2	-0.0	0.4	-0.0	0.0	0.1	-0.8	-0.4	-0.4	0.2	0.4	-0.5	0.1
High blood pressure (mother)	0.1	0.2	0.7	0.3	0.8	0.1	0.5	0.3	0.6	0.3	0.2	0.0	0.4	0.4	0.4	0.8	0.7	0.6	0.4	0.1	0.2	0.4
Frequency of tenseness / restlessness in last 2 weeks	0.1	0.1	0.8	-0.0	-0.9	-0.1	-0.0	0.3	0.3	-0.2	-0.4	-0.5	-0.3	-0.3	-0.4	0.3	0.1	-0.1	-0.4	-0.1	0.1	0.2
Pain all over the body in last month	0.1	0.1	0.8	-0.6	-0.4	0.1	-0.5	0.0	0.2	-0.0	0.1	0.5	-0.2	0.4	0.4	-0.2	-0.4	0.3	0.2	0.9	0.2	0.3
Time employed in main current job	0.1	0.1	1.2	1.1	0.4	0.2	0.0	-0.2	-0.1	-0.1	-0.0	0.1	-0.4	-0.0	-0.4	-0.5	-0.5	0.3	0.0	-0.1	0.2	-0.5
Frequency of tiredness / lethargy in last 2 weeks	0.1	0.1	0.5	0.5	-0.4	0.5	-0.0	0.5	0.1	0.0	0.1	0.2	-0.3	-0.3	-0.6	-0.5	-0.3	0.7	-0.4	0.2	0.4	0.2
Depression (self-reported)	0.1	0.1	1.3	0.1	-1.1	-0.2	-0.0	0.1	0.3	-0.0	-0.3	-0.3	-0.0	0.1	-0.1	0.3	0.2	-0.1	-0.0	0.3	0.1	0.3
Length of working week for main job	0.1	0.1	0.4	-0.1	0.3	-0.4	-0.5	-0.4	-0.3	-0.5	-0.3	-0.2	-0.5	-0.3	-0.3	-0.6	-0.5	-0.0	-0.3	-0.4	-0.4	-0.2
Mouth/teeth dental problems: Bleeding gums	0.1	0.1	0.3	-0.6	0.0	0.2	-0.2	0.1	0.0	-0.2	0.0	0.2	0.2	-0.0	-0.3	-0.5	-0.1	0.2	0.1	0.3	-0.1	0.6
Medication: Amlodipine	0.1	0.2	0.6	-0.4	0.2	-0.4	-0.4	-0.8	-0.4	-0.0	0.1	0.4	-0.2	0.7	0.5	-0.4	-0.3	-0.2	0.8	-0.3	-0.2	-0.6
Birth weight	0.1	0.2	0.7	0.7	-0.1	-0.5	-0.4	0.4	0.7	-0.3	-0.4	-0.6	-0.2	-0.4	-0.1	0.2	0.3	-0.4	-0.6	0.5	-0.3	0.8
Qualifications: College or University degree	0.1	0.3	0.7	-0.8	-0.7	-0.8	-0.6	-0.3	-0.1	-0.6	-0.6	-0.7	-0.4	-0.6	-0.1	0.0	-0.2	-0.9	-0.7	-0.0	-0.7	-0.1
Mood swings	0.1	0.2	1.5	-1.2	0.5	-0.5	-0.9	-0.2	-0.1	-0.1	-0.1	0.0	-0.6	0.2	-0.0	-0.5	-0.3	-0.3	0.1	-0.1	-0.1	-0.2
Friendships satisfaction	0.1	0.1	0.6	0.6	0.8	0.1	-0.1	0.1	0.1	-0.1	0.2	0.0	0.2	0.1	-0.1	-0.6	0.2	-0.1	0.3	-0.2	-0.1	0.4
Commuting to job workplace: Walk	0.1	0.1	0.3	-0.3	0.5	0.3	-0.0	0.3	0.3	0.3	0.5	0.3	0.3	0.4	0.4	-0.1	0.4	-0.1	0.4	0.1	0.2	0.4
Average weekly beer plus cider intake	0.1	0.2	1.0	0.1	-0.4	-0.4	0.3	-0.4	-0.3	-0.1	-0.5	-0.4	-0.4	0.0	0.4	0.7	-0.1	-0.1	0.1	-1.0	-0.0	-0.4
Alcohol drinker status: Previous	0.1	0.1	0.5	0.7	0.3	0.1	0.2	0.2	0.3	0.3	0.2	0.1	0.4	0.4	0.4	0.5	0.4	0.2	0.4	0.2	0.2	0.4
Hair Pigment	0.0	0.4	1.6	1.3	-1.1	0.3	0.8	0.8	0.3	0.1	-0.3	-0.8	0.1	-0.8	-0.7	0.7	0.5	0.4	-0.8	-0.6	0.4	0.4
Alcohol intake versus 10 years previously	0.0	0.0	0.2	0.0	-0.2	-0.1	0.1	0.2	0.2	-0.1	-0.2	-0.4	-0.1	-0.3	-0.4	0.2	0.1	0.1	-0.3	-0.2	0.0	0.0

Hub : Genes

IQCH

Models

Trait associations