[Hub]/) : Traits : Comparative height size at age 10 : ← →

chr15:73,342,781-75,159,433

Best TWAS P=7.64e-28 · Best GWAS P=3.35e-34 conditioned to 1.62e-11

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
7	GTEx	Testis	LOXL1-AS1	0.36	0.15	lasso	10	0.13	2.4e-06	-10.5	-10.9	7.6e-28	0.58	0.47	0.16	TRUE
2	GTEx	Cells Transformed fibroblasts	PML	0.14	0.02	lasso	4	0.02	1.9e-02	-7.4	7.1	1.6e-12	0.05	0.29	0.03	TRUE
11	The Cancer Genome Atlas	Breast Invasive Carcinoma	LOC283731	0.02	0.01	blup	15	0.01	1.9e-03	-4.7	-5.8	4.8e-09	0.20	0.01	0.64	TRUE
9	GTEx	Thyroid	LOXL1-AS1	0.15	0.03	enet	40	0.03	2.6e-03	-10.5	10.6	2.8e-26	-0.33	0.12	0.25	FALSE
3	GTEx	Cells Transformed fibroblasts	LOXL1-AS1	0.28	0.09	lasso	6	0.17	1.7e-12	4.7	8.9	7.2e-19	-0.64	0.84	0.16	FALSE
1	GTEx	Artery Tibial	LOXL1-AS1	0.12	0.11	enet	19	0.12	2.4e-09	-10.5	7.6	3.9e-14	-0.49	0.95	0.04	FALSE
6	GTEx	Skin Sun Exposed Lower leg	LOXL1-AS1	0.11	0.05	enet	11	0.10	7.3e-09	1.4	7.4	1.8e-13	-0.41	0.82	0.09	FALSE
5	GTEx	Skin Sun Exposed Lower leg	ISLR	0.08	0.00	enet	14	0.03	2.8e-03	2.5	5.9	4.2e-09	-0.12	0.14	0.09	FALSE
10	GTEx	Whole Blood	LOXL1-AS1	0.10	0.00	enet	33	0.00	5.8e-01	8.9	5.9	4.4e-09	-0.21	0.05	0.12	FALSE
8	GTEx	Thyroid	C15orf59	0.23	0.12	lasso	7	0.11	6.7e-09	5.3	5.7	1.1e-08	-0.19	1.00	0.00	FALSE
4	GTEx	Esophagus Mucosa	LOXL1-AS1	0.30	0.03	enet	37	0.05	2.0e-04	2.0	5.7	1.2e-08	-0.37	0.16	0.17	FALSE