[Hub]/) : Traits : Comparative height size at age 10 :

chr17:923,916-2,420,934

Best TWAS P=8.23e-14 · Best GWAS P=1.72e-11 conditioned to 0.914

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex SERPINF1 0.34 0.30 enet 24 0.34 2.2e-43 6.7 -6.4 1.4e-10 -0.96 0.00 1.00 FALSE
2 GTEx Adipose Subcutaneous SERPINF1 0.19 0.05 lasso 6 0.02 6.3e-03 6.7 -6.4 1.4e-10 -0.89 0.01 0.97 FALSE
3 GTEx Adipose Subcutaneous SMYD4 0.20 0.14 lasso 2 0.16 2.6e-13 6.7 -6.7 2.7e-11 -0.97 0.01 0.99 FALSE
4 GTEx Artery Tibial SMYD4 0.20 0.18 enet 10 0.18 8.2e-14 6.5 -6.6 4.8e-11 -0.98 0.01 0.99 FALSE
5 GTEx Brain Cortex SMYD4 0.34 0.17 lasso 4 0.23 5.3e-07 6.3 -7.5 8.2e-14 -0.86 0.01 0.95 TRUE
6 GTEx Cells Transformed fibroblasts SERPINF1 0.20 0.11 lasso 3 0.16 5.6e-12 6.7 -6.8 1.3e-11 -0.85 0.00 1.00 FALSE
7 GTEx Cells Transformed fibroblasts SMYD4 0.23 0.18 lasso 4 0.23 5.9e-17 6.5 -5.3 1.4e-07 -0.87 0.01 0.99 FALSE
8 GTEx Colon Sigmoid SMYD4 0.33 0.24 lasso 7 0.24 5.0e-09 6.5 -6.8 8.5e-12 -0.99 0.01 0.99 FALSE
9 GTEx Esophagus Muscularis SMYD4 0.24 0.16 lasso 3 0.18 3.1e-11 6.5 -6.8 1.4e-11 -0.97 0.01 0.99 FALSE
10 GTEx Lung SMYD4 0.10 0.09 lasso 3 0.09 1.4e-07 6.5 -6.5 7.2e-11 -0.97 0.01 0.99 FALSE
11 GTEx Nerve Tibial SMYD4 0.23 0.14 lasso 4 0.17 3.2e-12 6.3 -6.6 5.1e-11 -0.96 0.02 0.98 FALSE
12 GTEx Skin Not Sun Exposed Suprapubic SMYD4 0.28 0.06 enet 36 0.12 5.8e-07 6.7 -5.4 7.2e-08 -0.64 0.01 0.99 FALSE
13 GTEx Testis SMYD4 0.24 0.09 enet 14 0.10 2.9e-05 6.4 -5.8 9.1e-09 -0.78 0.02 0.96 FALSE
14 GTEx Thyroid SMYD4 0.32 0.13 enet 11 0.23 1.5e-17 6.7 -7.1 1.3e-12 -0.91 0.00 1.00 FALSE
15 YFS Blood SMYD4 0.17 0.15 bslmm 436 0.18 1.2e-55 6.5 -6.1 1.3e-09 -0.89 0.02 0.98 FALSE
16 YFS Blood WDR81 0.17 0.16 enet 22 0.18 1.3e-57 6.7 5.2 1.6e-07 0.85 0.00 1.00 FALSE
17 The Cancer Genome Atlas Glioblastoma Multiforme SMYD4 0.20 0.10 lasso 6 0.20 1.3e-06 6.3 -6.4 1.5e-10 -0.84 0.01 0.94 FALSE
18 The Cancer Genome Atlas Brain Lower Grade Glioma SMYD4 0.12 0.10 lasso 7 0.14 1.2e-15 6.3 -5.6 2.7e-08 -0.86 0.02 0.98 FALSE
19 The Cancer Genome Atlas Lung Adenocarcinoma SERPINF2 0.13 0.09 lasso 4 0.10 1.9e-11 -4.6 5.2 1.5e-07 0.06 1.00 0.00 TRUE
20 The Cancer Genome Atlas Prostate Adenocarcinoma SMYD4 0.08 0.09 lasso 9 0.08 6.3e-09 6.4 -6.2 7.3e-10 -0.97 0.01 0.99 FALSE
21 The Cancer Genome Atlas Thyroid Carcinoma SMYD4 0.08 0.09 lasso 3 0.07 3.5e-07 6.3 -6.4 1.9e-10 -0.92 0.03 0.97 FALSE