[Hub]/) : Traits : Comparative height size at age 10 : ← →

chr17:6,518,588-8,871,015

Best TWAS P=6.85e-12 · Best GWAS P=1.92e-13 conditioned to 0.0138

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
17	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	ALOXE3	0.04	0.00	blup	77	0.01	3.4e-02	-3.9	-6.9	6.9e-12	0.62	0.01	0.60	TRUE
19	The Cancer Genome Atlas	Brain Lower Grade Glioma	CHRNB1	0.05	0.04	blup	57	0.04	6.1e-05	5.5	6.3	2.4e-10	0.05	0.00	1.00	TRUE
2	CommonMind	Brain Pre-frontal Cortex	EIF5A	0.20	0.12	bslmm	446	0.10	1.2e-12	-5.1	-5.6	1.8e-08	-0.06	0.11	0.88	TRUE
11	METSIM	Adipose	PFAS	0.10	0.00	blup	450	0.03	1.7e-05	-5.7	-5.6	1.8e-08	0.36	0.02	0.82	TRUE
4	GTEx	Adipose Visceral Omentum	CHRNB1	0.29	0.14	lasso	5	0.14	1.0e-07	5.7	5.8	4.8e-09	0.02	0.01	0.99	FALSE
8	GTEx	Pancreas	TRAPPC1	0.17	0.00	lasso	6	0.01	1.5e-01	4.3	5.8	5.9e-09	-0.15	0.11	0.06	FALSE
6	GTEx	Esophagus Mucosa	CHRNB1	0.19	0.11	lasso	2	0.13	7.3e-09	5.7	5.7	1.1e-08	0.01	0.00	1.00	FALSE
9	GTEx	Skin Not Sun Exposed Suprapubic	CHRNB1	0.17	0.15	lasso	3	0.16	7.4e-09	5.7	5.7	1.5e-08	0.01	0.01	0.99	FALSE
7	GTEx	Muscle Skeletal	EIF5A	0.14	0.06	enet	35	0.05	4.2e-06	-4.6	-5.6	2.1e-08	-0.01	0.32	0.67	FALSE
5	GTEx	Breast Mammary Tissue (Male)	CHRNB1	0.28	-0.01	lasso	6	0.02	9.6e-02	5.7	5.5	3.3e-08	0.01	0.01	0.83	FALSE
18	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	C17orf68	0.05	0.00	blup	59	0.03	3.3e-04	-3.7	-5.5	3.6e-08	0.47	0.01	0.93	FALSE
16	The Cancer Genome Atlas	Glioblastoma Multiforme	AMAC1L3	0.14	0.12	lasso	3	0.12	1.8e-04	5.4	-5.5	4.0e-08	-0.06	0.01	0.86	FALSE
20	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	EIF5A	0.03	0.03	blup	52	0.03	4.2e-04	-4.8	-5.5	4.1e-08	0.02	0.02	0.96	FALSE
1	CommonMind	Brain Pre-frontal Cortex	CHRNB1	0.09	0.06	lasso	2	0.08	9.8e-10	5.7	5.4	5.8e-08	0.02	0.00	1.00	FALSE
13	YFS	Blood	CHRNB1	0.04	0.02	lasso	5	0.04	8.5e-12	5.8	5.4	6.8e-08	0.03	0.00	1.00	FALSE
15	The Cancer Genome Atlas	Breast Invasive Carcinoma	AURKB	0.02	0.01	blup	49	0.01	2.9e-03	1.8	-5.4	7.0e-08	0.39	0.00	0.63	FALSE
3	CommonMind	Brain Pre-frontal Cortex	PFAS	0.10	0.09	lasso	4	0.10	8.9e-13	-4.0	-5.3	1.1e-07	0.46	0.99	0.01	FALSE
10	GTEx	Stomach	CHRNB1	0.28	0.19	lasso	4	0.23	2.0e-11	5.7	5.3	1.2e-07	0.00	0.00	1.00	FALSE
12	ROSMAP	Brain Pre-frontal Cortex	PFAS	0.08	0.02	enet	10	0.03	4.4e-05	-5.7	-5.3	1.4e-07	0.40	0.91	0.03	FALSE
21	The Cancer Genome Atlas	Prostate Adenocarcinoma	CHRNB1	0.18	0.09	enet	10	0.10	4.9e-11	5.7	5.3	1.4e-07	0.01	0.00	1.00	FALSE
14	YFS	Blood	EIF5A	0.61	0.64	enet	29	0.65	1.4e-287	-5.1	-5.2	2.3e-07	-0.02	0.11	0.89	FALSE