TWAS hub - SMYD4

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Adipose Subcutaneous	0.2020	0.0440	1.4e-07	0.137	NA	0.150	NA	0.163	2.9e-11	NA	2.7e-12	NA	2.6e-13
2	GTEx	Artery Tibial	0.1964	0.0437	5.2e-07	0.179	NA	0.177	NA	0.174	5.6e-14	NA	8.2e-14	NA	1.3e-13
3	GTEx	Brain Cortex	0.3370	0.1060	2.7e-03	0.173	NA	0.159	NA	0.230	1.7e-05	NA	3.8e-05	NA	5.3e-07
4	GTEx	Cells Transformed fibroblasts	0.2270	0.0500	1.4e-07	0.181	NA	0.216	NA	0.227	1.5e-13	NA	3.8e-16	NA	5.9e-17
5	GTEx	Colon Sigmoid	0.3340	0.0770	2.7e-05	0.240	NA	0.227	NA	0.241	5.1e-09	NA	1.5e-08	NA	5.0e-09
6	GTEx	Esophagus Muscularis	0.2380	0.0590	3.7e-05	0.163	NA	0.167	NA	0.182	4.1e-10	NA	2.4e-10	NA	3.1e-11
7	GTEx	Lung	0.0956	0.0341	3.2e-03	0.087	NA	0.086	NA	0.093	3.4e-07	NA	3.9e-07	NA	1.4e-07
8	GTEx	Muscle Skeletal	0.1323	0.0406	5.8e-04	0.039	NA	0.065	NA	0.075	9.3e-05	NA	5.5e-07	NA	8.3e-08
9	GTEx	Nerve Tibial	0.2269	0.0545	1.8e-05	0.141	NA	0.151	NA	0.172	3.7e-10	NA	8.0e-11	NA	3.2e-12
10	GTEx	Skin Not Sun Exposed Suprapubic	0.2780	0.0730	4.7e-04	0.056	NA	0.117	NA	0.100	5.0e-04	NA	5.8e-07	NA	3.8e-06
11	GTEx	Skin Sun Exposed Lower leg	0.1710	0.0510	5.5e-04	0.000	NA	0.025	NA	0.031	3.3e-01	NA	3.4e-03	NA	1.3e-03
12	GTEx	Testis	0.2420	0.0850	3.4e-03	0.086	NA	0.102	NA	0.091	1.2e-04	NA	2.9e-05	NA	7.9e-05
13	GTEx	Thyroid	0.3170	0.0590	4.4e-08	0.130	NA	0.230	NA	0.185	3.8e-10	NA	1.5e-17	NA	4.2e-14
14	METSIM	Adipose	0.1049	0.0326	3.2e-05	0.060	0.033	0.052	0.040	0.058	2.7e-09	9.5e-06	2.8e-08	1.0e-06	3.9e-09
15	YFS	Blood	0.1727	0.0244	0.0e+00	0.151	0.150	0.173	0.177	0.164	4.3e-47	1.1e-46	2.4e-54	1.2e-55	2.8e-51
16	TCGA	Breast Invasive Carcinoma	0.0406	0.0148	5.9e-09	0.036	0.038	0.041	NA	0.043	6.9e-08	2.3e-08	8.7e-09	NA	3.7e-09
17	TCGA	Cervical Squamous Cell Carcinoma	0.1340	0.0650	8.6e-04	0.053	0.058	0.089	NA	0.086	1.3e-03	7.7e-04	3.8e-05	NA	5.2e-05
18	TCGA	Glioblastoma Multiforme	0.2030	0.0800	3.7e-04	0.102	0.168	0.190	NA	0.196	5.1e-04	8.4e-06	2.0e-06	NA	1.4e-06
19	TCGA	Kidney Renal Clear Cell Carcinoma	0.0343	0.0176	1.5e-03	0.039	0.018	0.035	NA	0.029	2.7e-05	3.5e-03	6.7e-05	NA	2.7e-04
20	TCGA	Brain Lower Grade Glioma	0.1214	0.0379	9.9e-14	0.102	0.139	0.140	NA	0.140	1.3e-11	1.5e-15	1.4e-15	NA	1.2e-15
21	TCGA	Pancreatic Adenocarcinoma	0.1720	0.0750	5.1e-04	0.062	0.088	0.074	NA	0.070	1.4e-03	1.5e-04	5.2e-04	NA	6.8e-04
22	TCGA	Prostate Adenocarcinoma	0.0796	0.0285	3.8e-09	0.094	0.080	0.078	NA	0.082	4.5e-10	9.3e-09	1.6e-08	NA	6.3e-09
23	TCGA	Stomach Adenocarcinoma	0.0600	0.0320	4.5e-03	0.000	0.006	0.001	NA	0.003	3.5e-01	1.0e-01	2.7e-01	NA	1.8e-01
24	TCGA	Testicular Germ Cell Tumors	0.1050	0.0500	4.2e-03	0.093	0.080	0.050	NA	0.060	3.7e-04	8.9e-04	7.5e-03	NA	3.6e-03
25	TCGA	Thyroid Carcinoma	0.0760	0.0280	5.7e-07	0.086	0.059	0.056	NA	0.068	9.0e-09	2.2e-06	3.5e-06	NA	3.5e-07

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17	18	19	20	21	22	23	24	25
Comparative height size at age 10	5.1	28.0	55.8	-6.7	-6.6	-7.5	-5.3	-6.8	-6.8	-6.5	-1.6	-6.6	-5.4	-4.0	-5.8	-7.1	-0.6	-6.1	-4.1	-1.3	-6.4	-2.5	-5.6	0.4	-6.2	-1.0	-2.6	-6.4
Alcohol drinker status: Previous	5.0	5.7	11.2	-2.8	-3.2	-2.7	-3.0	-3.0	-3.3	-3.0	0.2	-3.1	-0.8	-0.9	-2.2	-2.4	-1.6	-2.8	-2.3	-1.6	-2.8	-1.9	-2.6	-1.0	-2.7	-1.1	-1.4	-2.9
Ever used hormone-replacement therapy (HRT)	4.9	6.2	15.1	-2.3	-2.1	-1.9	-3.2	-2.1	-2.1	-2.4	2.6	-2.4	0.7	0.3	-1.6	-1.0	-2.9	-0.9	-3.5	-2.3	-1.7	-3.9	-2.9	-2.3	-2.4	-3.8	-3.9	-2.6
Forced expiratory volume in 1-second (FEV1), Best measure	4.3	13.9	28.8	-4.4	-4.3	-4.6	-2.2	-4.8	-4.8	-4.3	-4.3	-4.5	-5.2	-4.1	-4.7	-5.4	2.3	-4.5	-0.6	1.0	-3.9	-0.1	-2.3	1.3	-4.3	0.2	-0.1	-4.1
Forced vital capacity (FVC), Best measure	4.2	15.3	28.7	-4.7	-4.8	-5.4	-2.9	-5.2	-5.2	-4.7	-3.2	-4.9	-5.2	-3.6	-4.6	-5.3	1.5	-4.8	-1.6	-0.0	-4.5	-0.4	-3.0	1.4	-4.6	-0.2	-0.8	-4.4
Standing height	4.0	40.1	78.1	-8.1	-7.7	-6.8	-6.3	-8.3	-8.2	-7.8	-2.3	-8.0	-6.6	-5.2	-6.7	-8.8	0.5	-7.0	-4.9	-1.6	-8.4	-2.6	-6.8	1.2	-7.7	-1.5	-3.4	-7.7
Birth weight of first child	4.0	7.3	17.0	-3.2	-3.7	-2.2	-2.7	-3.8	-3.7	-3.4	-0.7	-3.2	-3.5	-1.5	-1.7	-4.1	0.6	-3.5	-2.1	-1.8	-2.8	-1.4	-2.4	0.0	-3.6	-1.8	-1.3	-2.8
Hearing aid user	3.6	4.1	10.3	-2.3	-2.5	-1.6	-2.3	-2.3	-2.8	-2.5	-0.8	-2.4	-3.2	-2.1	-1.5	-2.1	0.3	-2.6	-1.3	-1.1	-2.5	-2.0	-2.1	-1.1	-2.4	-0.2	-0.3	-2.3
Had menopause	3.5	4.3	9.2	-2.4	-2.3	-2.4	-2.6	-2.2	-2.5	-2.4	0.9	-2.7	-0.5	-1.1	-1.1	-1.8	-1.4	-1.7	-2.4	-1.0	-1.9	-3.0	-2.4	-1.8	-2.3	-1.7	-2.2	-2.8
Breast cancer (self-reported)	3.4	4.1	14.1	2.4	2.4	1.2	1.5	2.5	2.4	2.4	2.0	2.3	3.8	2.5	1.6	3.1	-1.7	3.1	0.5	0.6	1.6	0.6	1.2	0.3	2.4	-0.2	-0.1	1.9
Fasting Glucose	3.3	3.9	6.5	-2.3	-2.3	-1.8	-2.5	-2.4	-2.5	-2.2	0.0	-2.3	-0.9	-0.9	-2.4	-2.0	-0.9	-2.0	-2.3	-1.8	-2.3	-1.8	-2.5	-0.7	-2.5	-1.5	-1.4	-2.2
Height	3.3	62.6	108.2	-9.9	-9.5	-8.5	-8.3	-9.9	-10.0	-9.9	-2.2	-10.2	-8.3	-6.5	-8.4	-10.3	0.2	-9.1	-6.5	-2.0	-10.4	-4.3	-8.8	0.9	-9.4	-1.3	-4.8	-9.9
Sitting height	3.3	23.3	43.7	-5.9	-5.5	-6.6	-3.7	-5.8	-5.6	-5.7	-3.9	-5.8	-5.7	-5.1	-6.1	-6.6	2.8	-5.5	-1.9	1.0	-6.4	-1.0	-4.3	2.2	-5.4	1.0	-1.3	-5.7
Alcohol usually taken with meals	3.2	5.2	9.3	2.8	3.0	1.7	2.9	2.7	2.9	3.0	0.7	3.0	0.6	1.4	2.0	2.1	0.7	1.8	2.0	1.7	2.9	2.2	2.9	1.1	3.0	1.7	1.9	2.9
Forced vital capacity (FVC)	3.2	12.4	26.4	-4.3	-4.3	-5.1	-2.8	-4.6	-4.7	-4.2	-2.9	-4.4	-4.5	-3.1	-4.4	-4.7	1.1	-4.1	-1.5	-0.0	-4.0	-0.8	-2.9	0.8	-4.1	-0.2	-1.0	-4.1
Pulse rate	3.2	5.4	10.5	2.5	2.7	2.1	3.2	2.5	2.5	2.6	-0.5	2.5	0.9	1.0	1.9	1.9	0.7	1.9	2.7	3.1	2.6	2.5	2.8	1.6	2.9	2.6	2.6	2.2
Osteoporosis (self-reported)	3.2	4.0	8.8	-1.9	-1.9	-1.2	-2.8	-1.9	-2.0	-2.1	2.1	-2.1	-0.6	0.2	-1.5	-1.3	-2.5	-1.2	-3.0	-1.9	-1.8	-1.6	-2.5	-1.3	-1.8	-2.8	-2.5	-2.3
Happiness	3.1	3.7	10.6	2.1	1.3	3.1	0.8	1.4	1.1	1.9	2.1	1.9	1.3	3.2	3.0	1.5	-1.8	1.9	0.3	-2.5	2.6	0.5	1.8	-1.0	1.4	-2.5	-0.0	2.4
Wears glasses or contact lenses	3.1	3.6	8.4	-2.2	-2.3	-2.7	-2.0	-2.0	-2.1	-2.3	-0.7	-2.3	-2.6	-1.9	-1.2	-1.2	-0.0	-2.7	-1.1	-0.7	-2.1	-2.9	-1.7	-1.4	-2.0	-0.4	-0.6	-2.3
Medication: Ramipril	2.9	3.7	7.3	-2.3	-2.7	-2.4	-2.2	-2.4	-2.6	-2.5	-0.2	-2.2	-1.0	-1.3	-1.6	-2.3	0.2	-2.5	-1.7	-1.1	-1.7	-1.9	-2.1	-1.0	-2.5	-0.4	-1.2	-2.2
Illnesses of father: None of the above (group 1)	2.9	3.5	7.9	2.0	1.8	2.3	2.6	1.7	1.6	1.8	-1.4	1.9	0.1	0.7	1.5	0.9	2.0	1.4	2.8	1.6	2.0	2.7	2.6	1.9	1.7	1.3	1.9	2.1
Heart attack/myocardial infarction (self-reported)	2.9	3.7	8.6	-2.4	-2.6	-2.8	-1.6	-2.5	-2.6	-2.4	-0.9	-2.2	-1.1	-1.8	-2.3	-2.9	0.8	-2.1	-1.1	0.2	-1.8	-1.2	-1.7	0.2	-2.4	0.1	-1.0	-2.4
Heart attack	2.8	3.6	8.4	-2.4	-2.5	-2.8	-1.5	-2.5	-2.6	-2.4	-1.1	-2.2	-0.9	-1.7	-2.2	-2.9	0.9	-2.0	-1.0	0.0	-1.8	-1.4	-1.7	0.2	-2.5	0.0	-1.0	-2.3
Forced expiratory volume in 1-second (FEV1)	2.7	9.2	19.4	-3.6	-3.4	-3.9	-1.7	-3.9	-4.0	-3.5	-3.5	-3.7	-4.2	-3.0	-4.3	-4.4	1.6	-3.4	-0.4	1.0	-3.0	-0.5	-1.9	0.9	-3.5	0.4	-0.3	-3.4
Forced expiratory volume in 1-second (FEV1), predicted	2.7	5.6	14.4	-2.9	-2.7	-2.1	-1.9	-2.9	-3.0	-2.9	-1.3	-3.0	-3.0	-1.9	-3.0	-3.8	0.8	-2.9	-1.2	0.1	-3.0	-0.8	-2.1	1.6	-2.8	0.5	-0.8	-2.7
Friendships satisfaction	2.7	3.3	11.4	1.7	1.0	2.4	0.0	1.1	1.0	1.5	3.0	1.7	-0.1	3.0	2.5	1.3	-1.8	1.7	-0.8	-2.9	2.0	-0.2	1.1	-1.3	1.1	-3.4	-1.0	1.9
Number of incorrect matches in round	2.5	4.2	8.9	-2.0	-2.1	-0.9	-2.9	-1.9	-1.9	-2.1	1.5	-1.9	-0.1	0.4	-0.5	-1.1	-1.7	-1.1	-2.8	-2.9	-1.1	-2.7	-2.5	-2.7	-2.1	-3.0	-3.0	-2.0
Birth weight	2.5	5.3	11.7	-2.7	-3.1	-3.0	-1.9	-3.0	-2.9	-2.5	-1.5	-2.5	-3.4	-1.8	-3.2	-3.0	0.6	-2.4	-1.2	-0.5	-2.2	-2.5	-1.9	-0.7	-2.8	-0.4	-1.0	-2.4
Ever had stillbirth, spontaneous miscarriage or termination	2.4	2.6	11.1	1.2	1.2	0.2	-0.4	1.5	1.6	1.2	3.3	1.1	2.5	2.2	1.4	1.8	-3.0	1.9	-1.2	-2.2	0.4	-0.5	-0.5	-0.9	1.1	-1.3	-1.1	1.1
Forced expiratory volume in 1-second (FEV1), predicted percentage	2.4	5.1	11.7	-2.6	-2.7	-3.3	-1.4	-2.8	-2.9	-2.5	-2.4	-2.7	-2.9	-2.4	-3.4	-2.7	1.5	-1.9	-0.5	0.6	-2.5	-0.9	-1.7	0.7	-2.8	-0.1	-0.7	-2.6
Mineral and other dietary supplements	2.3	3.1	17.1	0.8	0.9	0.7	2.1	0.8	0.9	0.8	-2.6	0.8	-1.3	-1.3	-0.1	-0.3	2.7	-0.4	2.4	2.9	0.1	1.8	1.4	1.8	1.0	4.1	2.9	0.8
Serious illness, injury or assault to yourself	2.1	2.5	5.8	-2.0	-2.1	-2.3	-1.5	-2.0	-1.9	-2.0	-0.1	-1.9	-1.4	-1.5	-1.9	-2.4	-0.1	-2.4	-1.2	-0.4	-1.4	-0.7	-1.3	-0.8	-1.8	-0.4	-0.5	-1.9
Mean time to correctly identify matches	2.1	4.1	10.1	-2.5	-2.0	-2.8	-2.7	-1.9	-1.4	-2.3	1.4	-2.3	-1.5	-1.3	-1.3	-2.1	-1.5	-1.8	-2.9	-1.1	-2.9	-1.3	-3.2	-0.9	-1.8	-0.6	-1.8	-2.5
Financial situation satisfaction	2.1	2.6	7.3	1.9	1.5	2.3	1.8	1.4	1.4	1.9	0.2	2.0	1.2	1.8	2.4	1.1	-0.3	1.6	1.5	-0.5	2.7	1.0	2.1	-0.4	1.4	-0.0	1.1	2.3
Supplements: Fish oil (including cod liver oil)	2.1	2.7	11.8	-0.3	-0.3	-0.2	-1.6	-0.1	-0.1	-0.3	3.0	-0.3	2.3	1.7	0.4	1.1	-2.4	1.1	-2.3	-2.4	-0.3	-2.1	-1.4	-1.0	-0.5	-3.4	-2.8	-0.4
Supplements: Calcium	2.1	2.3	7.3	-1.4	-1.0	-1.6	-2.2	-1.2	-1.1	-1.4	2.3	-1.2	-1.1	-0.2	0.3	-0.8	-1.5	-1.1	-2.7	-1.3	-1.2	-1.3	-1.8	-1.3	-1.2	-2.3	-2.4	-1.6
Worry (Nagel 2018)	2.0	4.2	18.7	0.0	-0.3	-0.4	-2.2	0.2	0.2	-0.0	4.3	-0.1	1.5	2.1	1.1	1.8	-3.5	0.5	-3.3	-3.3	0.4	-1.9	-1.9	-3.9	0.2	-2.5	-2.6	-0.3
Prostate Cancer	2.0	2.8	5.9	-2.0	-2.0	-1.9	-1.9	-2.0	-2.0	-1.9	-0.4	-2.0	-1.7	-1.1	-1.2	-1.7	-1.8	-1.9	-1.5	-1.2	-1.1	-1.2	-1.9	-2.4	-1.8	-0.1	-0.9	-1.8
Number of self-reported non-cancer illnesses	2.0	3.5	8.5	-2.3	-2.3	-2.9	-1.9	-2.1	-2.2	-2.3	-0.1	-2.3	-0.7	-1.5	-1.4	-2.4	-0.1	-2.6	-1.8	-0.5	-2.2	-2.0	-2.0	-0.6	-2.1	-0.4	-0.7	-2.3
Supplements: Zinc	1.9	2.0	7.2	1.2	1.4	1.6	0.4	0.9	0.9	1.3	2.7	1.3	1.2	2.3	2.3	1.4	-2.1	1.4	-0.7	-1.1	1.6	-0.1	0.8	-0.9	1.2	-1.8	-0.8	1.1
Smoking status: Current	1.9	3.0	6.7	1.5	1.9	2.5	2.3	1.5	1.6	1.5	-0.9	1.5	1.1	0.3	1.1	0.9	0.9	1.1	2.3	1.9	1.3	2.6	2.1	2.5	1.8	1.6	2.1	1.7
Current tobacco smoking	1.8	2.9	7.8	1.4	1.8	2.3	2.2	1.4	1.6	1.4	-1.1	1.4	0.9	-0.1	0.9	0.7	1.2	1.0	2.3	2.3	1.0	2.8	2.0	2.7	1.7	1.9	2.2	1.4
Nervous feelings	1.8	3.3	13.6	-0.7	-1.0	-1.2	-2.4	-0.6	-0.5	-0.7	3.7	-0.7	0.1	1.7	0.5	0.6	-2.9	-0.4	-3.4	-3.3	-0.6	-1.7	-2.4	-2.7	-0.4	-1.9	-2.1	-0.7
Worrier / anxious feelings	1.8	3.4	13.3	0.6	0.2	0.6	-1.4	0.6	0.5	0.5	3.5	0.4	1.4	2.2	1.9	2.0	-3.6	0.8	-2.3	-3.1	1.0	-1.2	-0.9	-3.7	0.6	-2.3	-1.7	0.4
Neck or shoulder pain in last month	1.8	2.6	5.5	-1.8	-1.6	-2.1	-0.8	-1.4	-1.4	-1.8	-2.0	-1.8	-1.9	-2.3	-1.2	-2.0	1.7	-2.4	0.3	1.4	-2.3	0.2	-0.7	1.4	-1.2	0.9	0.7	-1.9
Neuroticism	1.7	4.0	15.8	0.8	0.3	1.1	-1.3	0.8	0.7	0.8	4.0	0.8	1.9	3.2	1.6	2.3	-3.6	1.4	-2.3	-3.2	1.2	-1.1	-0.8	-3.4	0.9	-2.4	-2.1	0.8
Pulse wave Arterial Stiffness index	1.7	2.0	4.5	-1.3	-1.4	-1.0	-1.9	-1.3	-1.6	-1.4	0.3	-1.4	-1.4	-0.3	-1.4	-0.8	-1.6	-0.9	-1.4	-2.0	-0.9	-1.9	-1.6	-1.9	-1.4	-2.1	-1.1	-1.2
Medication: Ibuprofen	1.7	2.0	5.4	1.5	1.5	2.3	1.0	1.5	1.7	1.6	1.1	1.7	1.3	1.5	1.9	1.2	-0.7	1.5	0.5	-0.6	2.2	1.4	1.4	-1.0	1.6	-0.7	0.2	1.7
Qualifications: nursing, teaching	1.7	2.7	6.8	2.0	1.8	1.8	1.7	1.9	1.9	1.9	-0.1	2.0	1.0	0.8	2.1	1.7	0.0	1.2	1.7	0.0	2.6	1.6	2.3	-0.7	1.9	0.3	1.2	2.3
Ever depressed for a whole week	1.7	2.1	5.8	1.0	0.9	1.4	-0.2	1.0	1.1	1.0	2.4	1.2	1.8	2.1	1.4	1.4	-1.6	1.5	-1.0	-1.9	1.5	-1.2	0.2	-2.1	0.8	-2.4	-1.4	0.9
Reaction Time	1.6	3.0	8.0	-2.0	-1.4	-2.3	-2.3	-1.5	-1.1	-1.8	1.4	-1.8	-1.7	-0.9	-1.2	-1.8	-1.7	-1.4	-2.6	-1.2	-2.6	-0.9	-2.8	-0.8	-1.4	-0.5	-1.4	-2.1
Hand grip strength (right)	1.6	4.3	8.3	-2.6	-2.7	-2.3	-2.1	-2.6	-2.7	-2.5	-0.8	-2.5	-2.9	-1.0	-2.5	-2.3	-0.2	-1.9	-1.7	-0.5	-2.0	-2.1	-2.4	-0.7	-2.5	-0.5	-1.5	-2.4
Tense / ‘highly strung’	1.6	2.6	10.7	0.8	0.8	1.1	-0.6	0.9	1.1	0.9	3.3	0.8	1.0	2.1	2.0	1.9	-3.1	1.1	-1.9	-2.3	1.0	-1.3	-0.4	-3.0	1.0	-1.6	-0.9	0.8
Reproduciblity of spirometry measurement using ERS/ATS criteria	1.6	1.9	5.4	1.6	1.4	1.1	0.8	1.9	1.9	1.4	1.1	1.4	1.4	1.3	1.0	2.0	-1.2	0.9	0.8	-0.7	2.3	0.4	1.4	-1.7	1.9	-0.1	0.6	1.6
Arm predicted mass (right)	1.6	7.9	19.6	-2.9	-2.3	-3.9	-0.2	-2.8	-2.6	-2.5	-3.9	-2.7	-2.6	-3.8	-4.4	-4.2	2.9	-3.0	0.5	3.8	-2.2	0.1	-1.2	2.3	-2.6	3.0	0.2	-3.0
Vascular/heart problems diagnosed by doctor	1.6	4.4	10.6	2.4	2.6	3.3	2.2	2.3	2.2	2.2	-0.1	2.2	0.2	1.4	3.0	2.1	-0.6	2.3	2.3	0.8	2.2	2.5	2.7	1.4	2.4	-0.1	1.5	2.5
Neuroticism (Nagel 2018)	1.5	3.5	13.9	0.5	-0.0	0.7	-1.5	0.5	0.6	0.4	3.6	0.4	1.6	2.2	1.9	2.1	-3.7	0.9	-2.4	-3.1	0.9	-1.0	-0.9	-3.6	0.7	-2.4	-1.7	0.4
Age at First Birth	1.5	2.2	5.1	-1.6	-1.7	-1.6	-1.7	-1.9	-1.9	-1.6	0.1	-1.6	-1.5	-0.7	-0.9	-1.5	-1.5	-1.6	-1.7	-1.5	-2.2	-1.3	-1.8	-0.6	-1.7	-1.0	-0.3	-1.5
Mean Putamen Volume	1.5	1.7	6.7	1.3	1.3	0.7	1.0	1.4	1.4	1.5	1.0	1.3	1.9	1.6	1.2	1.6	-1.0	1.2	0.4	-0.4	2.6	0.6	1.3	-1.5	1.3	-1.0	-0.3	1.4
Frequency of tenseness / restlessness in last 2 weeks	1.5	2.3	8.5	0.6	0.1	0.1	-0.9	0.4	0.6	0.6	2.9	0.5	1.0	2.4	1.3	1.4	-2.9	0.8	-1.8	-2.6	1.1	-1.1	-0.3	-2.5	0.4	-2.5	-1.6	0.7
Ever unenthusiastic/disinterested for a whole week	1.5	1.8	3.8	1.6	1.6	1.6	1.0	1.5	1.4	1.7	1.5	1.6	1.5	1.8	1.0	1.4	-1.4	1.8	0.3	0.4	1.9	0.4	1.4	-0.3	1.6	-1.1	-0.1	1.4
Ever highly irritable/argumentative for 2 days	1.5	1.8	4.4	1.3	1.2	2.0	0.8	0.9	0.9	1.4	1.5	1.5	1.5	2.0	0.9	1.3	-2.1	1.7	-0.1	-0.5	2.0	0.2	0.9	-1.5	1.3	-1.2	-0.1	1.3
Ever had prostate specific antigen (PSA) test	1.5	1.7	4.9	-0.9	-0.9	-1.2	-1.6	-0.9	-0.7	-0.7	1.3	-0.8	0.7	0.5	-0.6	-0.1	-1.6	0.3	-2.0	-1.5	-0.6	-2.2	-1.6	-2.2	-1.0	-1.9	-2.2	-0.9
Vitamin and mineral supplements	1.4	1.9	10.2	0.4	0.1	0.1	1.5	0.2	0.1	0.3	-2.5	0.3	-0.7	-1.3	-0.5	-0.1	2.3	-0.4	2.3	1.9	0.4	1.2	1.3	1.6	0.2	3.2	2.1	0.4
High blood pressure	1.4	3.9	9.0	-2.2	-2.5	-3.0	-2.2	-2.1	-2.0	-2.0	0.3	-2.0	-0.3	-1.2	-2.5	-1.9	0.2	-2.2	-2.4	-1.2	-2.0	-2.4	-2.6	-1.8	-2.2	-0.1	-1.4	-2.3
Hair/balding pattern: Pattern 2	1.4	1.8	5.4	1.4	1.8	2.3	1.3	1.8	1.6	1.3	-0.6	1.2	1.6	0.5	0.9	1.4	1.1	1.9	1.6	1.4	0.0	0.6	1.0	1.9	1.4	1.0	0.7	1.1
Weight	1.4	7.1	23.4	-2.8	-2.4	-3.9	-0.5	-2.8	-2.6	-2.4	-3.4	-2.6	-2.4	-3.3	-4.8	-4.1	1.9	-2.3	0.1	3.6	-2.0	-0.0	-1.5	1.9	-2.5	2.4	-0.3	-3.0
Medication: Amlodipine	1.4	1.9	9.6	0.1	-0.2	0.2	-1.2	-0.1	-0.3	0.0	2.9	-0.0	1.6	2.3	-0.3	1.0	-3.1	0.5	-2.0	-1.8	-0.1	-2.0	-1.2	-1.4	-0.1	-0.7	-1.6	-0.2
Medication: Ventolin 100micrograms inhaler	1.4	1.8	5.0	-1.3	-1.0	-1.6	-1.5	-1.1	-0.9	-1.1	1.4	-1.1	0.5	-0.4	-1.7	-1.0	-0.5	-0.7	-2.0	-1.0	-1.0	-2.0	-1.8	-1.4	-1.4	-1.2	-2.2	-1.4
Arm fat-free mass (right)	1.4	7.0	16.3	-2.6	-2.1	-3.7	-0.1	-2.6	-2.4	-2.2	-3.9	-2.5	-2.6	-3.6	-4.0	-4.0	2.9	-2.7	0.6	3.6	-1.8	-0.0	-1.1	1.8	-2.4	2.9	0.2	-2.7
Worry too long after embarrassment	1.4	2.3	10.5	-0.7	-1.0	0.0	-2.1	-0.5	-0.6	-0.8	1.8	-0.9	0.4	0.5	0.5	0.9	-2.7	-0.9	-2.3	-2.6	-0.9	-2.2	-1.7	-3.2	-0.5	-1.7	-1.4	-0.9
Eye problems/disorders: Cataract	1.4	1.7	5.6	-1.5	-1.2	-1.3	-1.5	-0.9	-0.9	-1.4	0.2	-1.5	-0.1	-0.7	-2.1	-1.0	0.0	-0.5	-1.5	0.1	-1.2	-0.9	-1.4	-0.3	-1.3	-2.4	-2.4	-1.8
Medication: Gliclazide	1.4	1.6	5.3	-1.2	-1.1	-1.5	-0.3	-0.7	-0.7	-1.1	-1.4	-1.0	-1.8	-1.6	-2.3	-1.6	2.2	-1.4	0.4	1.3	-0.8	0.4	-0.4	1.1	-0.8	1.4	0.1	-1.2
Arm fat-free mass (left)	1.4	7.2	18.3	-2.5	-1.9	-3.6	0.2	-2.4	-2.2	-2.0	-4.3	-2.3	-2.5	-3.8	-4.2	-3.9	3.4	-2.4	0.9	4.2	-1.6	0.5	-0.8	2.2	-2.2	2.9	0.2	-2.6
Neuroticism (2016)	1.3	1.9	11.0	-0.4	-0.6	-0.6	-1.7	-0.3	-0.2	-0.4	2.3	-0.4	-0.3	0.9	0.6	0.6	-3.3	0.1	-2.3	-2.5	-0.8	-1.6	-1.6	-2.4	-0.2	-1.4	-1.0	-0.5
Qualifications: CSEs or equivalent	1.3	1.8	5.1	1.4	1.6	1.9	1.9	1.0	0.9	1.5	-0.8	1.6	0.2	1.1	0.7	0.7	0.7	1.3	1.7	1.1	1.0	1.0	1.6	2.3	1.2	1.5	1.5	1.4
Trunk fat-free mass	1.3	7.4	17.6	-2.6	-2.1	-3.9	0.0	-2.6	-2.4	-2.2	-4.2	-2.4	-2.8	-3.7	-4.0	-4.1	3.2	-2.8	0.8	3.8	-1.7	0.7	-0.9	2.2	-2.3	3.0	0.3	-2.6
Trunk predicted mass	1.3	7.4	17.9	-2.6	-2.1	-3.9	0.1	-2.6	-2.4	-2.1	-4.2	-2.3	-2.8	-3.7	-4.0	-4.1	3.3	-2.7	0.9	3.9	-1.7	0.8	-0.9	2.2	-2.3	3.0	0.4	-2.6
Family relationship satisfaction	1.3	1.6	8.7	-0.3	-0.3	0.7	-1.1	-0.4	-0.2	-0.1	2.1	0.0	-0.2	1.3	0.3	-0.2	-1.6	0.7	-1.7	-2.4	0.0	-1.4	-0.8	-1.7	-0.7	-3.0	-2.2	-0.0
Qualifications: NVQ or HND or HNC or equivalent	1.3	1.6	5.1	-0.9	-0.7	-0.9	0.3	-0.6	-0.8	-0.9	-2.2	-1.0	-1.3	-2.1	-1.5	-1.6	2.0	-1.5	1.1	1.9	-0.5	0.0	-0.0	0.6	-0.7	2.3	1.1	-1.1
Illness, injury, bereavement, stress in last 2 years	1.3	1.6	3.5	-1.3	-1.3	-1.4	-1.9	-1.0	-1.1	-1.3	0.7	-1.2	0.1	-0.2	-0.7	-0.4	-1.2	-0.6	-1.6	-1.5	-1.2	-1.8	-1.8	-1.5	-1.3	-1.6	-1.6	-1.2
Myopia	1.3	1.9	10.7	-0.7	-1.1	-0.2	-1.8	-0.8	-0.7	-0.7	2.3	-0.6	0.3	1.1	0.6	0.0	-2.0	-0.8	-2.1	-3.3	-1.0	-2.1	-1.4	-1.6	-0.9	-1.5	-1.2	-0.3
Coronary Artery Disease (CAD)	1.2	1.4	6.4	-1.2	-1.4	-2.5	-1.3	-0.9	-0.7	-1.3	-0.6	-1.2	0.0	-1.1	-1.0	-0.6	-0.8	-1.4	-1.1	-0.9	-0.4	0.0	-1.2	-2.5	-1.0	-1.0	-0.7	-1.0
Crohns Disease (2012)	1.2	1.9	6.3	-1.6	-1.8	-0.8	-1.3	-1.9	-1.9	-1.5	-0.5	-1.5	-1.1	-0.6	-1.4	-1.4	0.0	-1.6	-0.9	-1.4	-2.5	-1.0	-1.3	0.8	-1.9	-1.3	-0.1	-1.2
Primary Biliary Cirrhosis	1.2	1.8	5.0	-1.5	-1.3	-0.9	-0.4	-1.4	-1.5	-1.4	-1.3	-1.5	-0.8	-1.1	-1.8	-2.1	2.2	-1.0	-0.0	1.2	-1.5	-0.0	-0.8	1.8	-1.6	0.4	-0.9	-1.6
Blood White Count	1.2	8.8	17.1	3.2	4.1	3.8	3.8	3.4	3.5	3.3	-1.1	3.3	0.9	1.0	1.0	2.3	0.4	3.4	3.5	3.1	3.4	3.1	3.5	2.0	3.5	3.1	2.7	3.0
Number of live births	1.2	1.7	4.6	1.6	1.5	1.1	1.1	1.7	1.7	1.6	0.5	1.6	1.0	0.5	1.8	1.6	1.3	0.6	0.8	-0.1	2.1	0.9	1.6	-0.7	1.6	0.2	0.5	1.5
Medication: Cholesterol lowering	1.2	1.8	3.9	-1.5	-1.9	-1.1	-1.4	-1.8	-2.0	-1.7	-0.4	-1.5	0.2	-1.0	-1.8	-1.8	0.7	-1.6	-1.0	-0.6	-1.3	-0.9	-1.1	0.1	-2.0	-1.2	-1.1	-1.4
Mood swings	1.2	2.2	8.5	1.0	0.7	1.6	-0.2	0.9	1.0	1.1	1.9	1.2	1.2	1.6	1.8	1.8	-1.5	1.2	-0.9	-2.3	1.4	-1.6	0.4	-2.9	0.9	-2.4	-0.7	1.3
Basal metabolic rate	1.2	6.8	19.6	-2.5	-2.0	-3.9	0.0	-2.6	-2.4	-2.0	-3.7	-2.3	-2.4	-3.3	-4.4	-4.0	2.7	-2.4	0.5	3.8	-1.5	0.3	-0.9	2.1	-2.3	2.8	-0.1	-2.6
Diastolic blood pressure, automated reading	1.2	3.6	11.4	-2.2	-2.1	-3.4	-1.5	-1.6	-1.6	-2.1	-1.0	-2.2	-1.8	-2.0	-3.1	-1.8	0.4	-2.1	-1.2	1.1	-1.8	-2.2	-2.1	-1.1	-1.6	0.9	-0.4	-2.6
Heart disease (siblings)	1.2	1.5	6.8	-1.4	-1.4	-2.6	-0.9	-1.5	-1.2	-1.3	-1.5	-1.3	-0.9	-1.8	-1.6	-1.5	0.4	-1.6	-0.5	0.1	-0.8	0.2	-0.9	-1.0	-1.3	0.2	-0.1	-1.2
Arm predicted mass (left)	1.2	5.9	16.0	-2.1	-1.6	-3.3	0.4	-2.1	-2.0	-1.7	-3.9	-1.9	-2.0	-3.3	-3.9	-3.6	3.3	-2.0	1.1	4.0	-1.4	0.4	-0.5	2.4	-2.0	2.8	0.3	-2.2
Depressed Affect (Nagel 2018)	1.1	2.4	6.9	1.2	0.6	1.6	-0.2	0.9	0.9	1.1	2.6	1.1	2.0	2.3	2.2	1.9	-2.1	1.3	-0.9	-2.4	1.5	0.1	0.6	-1.7	1.1	-2.0	-0.8	1.4
Depression (Nagel 2018)	1.1	1.7	11.2	-0.0	-0.5	-0.1	-1.2	-0.2	-0.1	-0.1	1.8	0.0	0.9	1.2	1.5	0.7	-2.5	-0.1	-1.7	-2.5	0.8	-0.4	-0.7	-3.3	0.0	-2.0	-0.8	0.1
Cardiovascular Disease	1.1	3.8	13.5	-2.3	-2.2	-2.4	-1.9	-2.1	-1.9	-2.0	0.0	-2.1	0.0	-1.2	-3.7	-2.1	0.1	-1.7	-2.1	-0.1	-1.9	-2.4	-2.6	-1.4	-2.1	0.4	-1.5	-2.5
Medication: Co-codamol	1.1	1.3	9.6	0.8	1.1	1.4	1.1	1.0	0.9	0.8	-1.0	0.7	-0.0	-0.7	0.3	0.7	0.1	0.2	1.2	1.9	-0.3	0.5	0.4	0.9	1.2	3.1	2.0	0.5
Impedance of leg (right)	1.1	5.3	21.0	-2.5	-2.4	1.3	-3.1	-2.4	-2.6	-2.9	0.2	-3.0	-2.7	-1.4	-0.3	-2.5	-1.0	-2.5	-2.2	-2.6	-4.6	-0.2	-2.8	0.6	-2.2	-2.1	0.1	-2.3
Pain all over the body in last month	1.1	1.2	3.9	1.0	0.9	1.1	1.5	0.9	0.9	1.0	-0.7	1.0	0.6	0.1	0.7	0.5	-0.3	0.6	1.4	1.5	0.7	1.5	1.2	1.1	1.2	2.0	1.8	0.9
Neuroticism score	1.1	2.2	9.0	0.0	-0.5	0.4	-1.6	0.0	-0.0	-0.1	2.6	-0.1	0.7	1.8	1.2	1.5	-2.4	0.1	-2.0	-3.0	0.4	-1.4	-0.9	-3.0	0.0	-2.3	-1.6	0.1
Seen doctor (GP) for nerves, anxiety, tension or depression	1.1	1.6	8.0	-1.1	-1.1	-1.1	-1.9	-0.6	-0.7	-1.2	1.3	-1.3	0.1	0.1	-0.1	-0.1	-1.5	-1.0	-1.9	-1.4	-0.4	-1.3	-1.5	-2.8	-0.7	-1.5	-1.9	-1.2
Number of full brothers	1.1	1.4	4.2	1.3	1.1	1.6	1.6	1.0	0.9	1.2	-0.7	1.1	-0.7	0.1	0.6	0.4	0.4	0.6	1.7	1.1	0.4	1.2	1.6	1.5	1.2	1.4	2.1	1.3
Eye problems/disorders: None of the above	1.1	1.2	4.1	1.4	1.1	0.7	0.9	1.1	1.1	1.3	0.9	1.4	1.3	1.5	2.0	1.6	-0.8	1.1	0.6	-0.2	0.9	0.2	0.7	0.2	1.2	1.2	1.0	1.4
Mouth/teeth dental problems: Loose teeth	1.1	1.3	5.0	-1.4	-0.5	-1.9	-0.7	-0.5	-0.3	-1.2	-0.9	-1.3	-0.6	-2.2	-1.5	-1.0	0.7	-1.4	-0.4	1.9	-1.1	0.0	-1.1	-0.8	-0.3	1.2	-0.2	-1.8
Whole body fat-free mass	1.1	6.5	17.4	-2.5	-2.0	-4.0	0.1	-2.5	-2.3	-2.0	-3.7	-2.2	-2.4	-3.3	-4.2	-3.8	2.8	-2.4	0.6	3.8	-1.3	0.3	-0.8	2.0	-2.2	2.8	-0.0	-2.5
Whole body water mass	1.1	6.5	17.3	-2.5	-2.0	-4.0	0.1	-2.5	-2.3	-2.0	-3.7	-2.1	-2.5	-3.3	-4.2	-3.9	2.8	-2.4	0.6	3.7	-1.3	0.3	-0.8	2.0	-2.2	2.7	-0.0	-2.5
Miserableness	1.1	1.9	5.0	1.5	1.1	1.6	0.7	1.4	1.4	1.4	1.7	1.4	2.1	2.1	2.2	1.8	-1.1	1.3	0.3	-1.0	1.4	0.3	1.3	-0.2	1.4	-0.5	-0.0	1.5
Guilty feelings	1.1	1.6	6.8	1.0	0.9	0.9	-0.3	1.2	1.3	1.0	1.9	0.9	0.9	1.7	2.2	2.0	-2.6	1.5	-0.9	-0.9	0.6	-0.3	-0.2	-1.4	1.2	-1.1	-0.7	0.6
Impedance of whole body	1.1	5.8	18.5	-2.1	-2.3	1.0	-3.6	-2.2	-2.3	-2.5	2.2	-2.5	-1.5	0.4	-0.0	-1.4	-3.0	-1.5	-3.3	-4.3	-4.1	-1.1	-3.0	-0.4	-1.9	-3.5	-1.2	-1.9
Bipolar Disorder (2018)	1.0	1.6	5.6	-1.5	-1.2	-1.1	-1.1	-1.4	-1.2	-1.4	-0.3	-1.4	-2.4	-1.4	-1.3	-1.7	1.3	-1.5	-0.9	0.1	-1.6	0.0	-1.2	0.2	-1.5	-0.4	-0.8	-1.5
Crohns Disease (2017)	1.0	2.1	11.8	-1.5	-1.4	-1.0	-1.7	-1.5	-1.3	-1.4	0.4	-1.4	-0.5	-0.5	-0.9	-0.8	-2.0	-1.1	-1.6	-1.8	-1.3	-1.1	-1.2	-1.5	-1.5	-3.4	-1.1	-1.2
Major Depression (MDD)	1.0	1.2	4.7	1.3	1.4	1.3	0.7	1.3	1.5	1.4	0.6	1.5	0.0	0.6	2.2	1.2	-0.5	1.3	0.3	-0.1	0.6	0.0	0.4	0.0	1.4	0.8	1.1	1.3
Allergy or Eczema	1.0	2.5	12.5	1.7	2.0	3.5	1.5	1.9	1.8	1.6	-0.1	1.7	1.1	0.4	2.4	1.4	0.2	1.4	1.5	0.5	2.4	0.5	1.6	-0.9	1.7	0.7	0.7	1.6
High blood pressure (mother)	1.0	1.3	5.4	1.4	1.1	1.1	0.6	1.0	0.5	1.2	1.5	1.2	1.9	2.3	0.5	1.4	-0.9	1.5	-0.1	-0.5	1.0	-1.7	0.8	0.1	0.7	-1.1	-0.7	1.0
Impedance of leg (left)	1.0	4.8	20.7	-2.2	-2.2	1.8	-3.1	-2.2	-2.5	-2.7	0.8	-2.7	-1.9	-0.9	-0.2	-1.9	-1.0	-2.0	-2.3	-3.0	-4.5	-0.7	-2.7	0.5	-2.1	-2.6	-0.3	-2.1
Trunk fat mass	1.0	4.5	19.2	-2.4	-2.2	-3.0	-1.1	-2.4	-2.2	-2.2	-1.6	-2.4	-1.5	-2.0	-4.4	-3.0	-0.2	-1.5	-0.9	2.1	-2.3	-0.5	-1.8	1.5	-2.1	0.9	-0.8	-2.7
Impedance of arm (left)	1.0	4.8	15.6	-1.7	-2.0	0.1	-3.2	-1.9	-2.0	-2.0	2.6	-2.0	-1.2	0.9	0.0	-0.9	-3.7	-1.0	-3.3	-3.9	-2.9	-1.1	-2.6	-0.9	-1.4	-3.3	-1.6	-1.6
Pulse wave reflection index	1.0	1.3	8.6	-0.2	-0.5	0.4	-1.3	-0.3	-0.6	-0.4	0.7	-0.4	-0.3	0.9	-0.2	-0.0	-1.5	0.4	-0.8	-2.9	-0.4	-2.2	-0.7	-1.4	-0.8	-2.4	-1.3	-0.0
Comparative body size at age 10	1.0	2.8	10.0	1.7	1.1	0.1	2.4	1.5	1.6	1.7	-0.9	1.7	0.7	1.0	0.0	1.2	1.2	1.2	2.5	2.2	3.2	1.7	2.7	0.4	1.8	1.6	1.4	1.7
Pulse wave peak to peak time	1.0	1.2	4.4	0.6	0.8	0.5	1.5	0.6	0.9	0.8	-0.6	0.8	0.8	-0.1	1.0	0.0	1.7	0.2	1.1	1.9	0.3	1.6	1.1	2.1	0.8	2.1	1.0	0.6
Hypertension (Self-reported)	1.0	2.7	5.8	-1.8	-2.0	-2.3	-2.0	-1.7	-1.5	-1.5	1.0	-1.5	0.0	-0.4	-2.1	-1.4	-0.4	-1.6	-2.4	-1.1	-1.6	-2.4	-2.4	-1.6	-1.7	-0.1	-1.6	-1.8
Illnesses of father: Heart disease	1.0	1.4	4.5	-1.2	-1.4	-2.1	-1.5	-1.0	-0.9	-1.2	0.4	-1.4	-0.8	-1.4	-1.2	-1.0	-0.8	-1.7	-1.3	-1.1	-1.6	-0.9	-1.3	-1.0	-1.0	-0.6	-0.1	-1.1
Mother’s age at death	1.0	1.3	5.2	-0.7	-0.4	-0.4	-1.2	-0.6	-0.5	-0.6	2.0	-0.7	0.7	1.0	-0.7	0.5	-2.3	0.4	-1.9	-0.9	-0.3	-1.2	-1.3	-1.2	-0.5	-1.7	-1.8	-0.8
Eye problems/disorders: Glaucoma	1.0	1.2	7.4	-0.4	-0.4	-0.0	0.9	-0.5	-0.6	-0.4	-2.7	-0.6	-0.5	-1.3	-0.8	-1.3	1.5	-0.9	1.9	1.3	-0.1	0.8	1.1	1.1	-0.3	1.0	1.8	-0.1
Medication: Lisinopril	1.0	1.4	5.4	1.1	1.2	1.1	0.6	1.2	1.1	1.2	1.7	1.1	2.3	1.9	0.5	1.7	-1.5	1.7	-0.2	-0.1	-0.0	-0.9	0.2	1.1	1.1	-0.3	-0.3	0.9
BMI	0.9	5.1	23.4	1.5	1.8	-0.7	3.2	1.8	2.0	1.9	-2.5	1.6	1.9	-0.5	-1.9	0.4	1.7	1.5	3.0	4.8	2.4	2.2	2.3	1.7	1.9	4.2	1.9	1.2
Waist Hip Ratio (WHR)	0.9	3.8	12.6	-2.0	-2.4	-2.8	-1.8	-2.6	-2.5	-2.0	0.7	-1.9	-1.6	0.0	-0.7	-2.9	-0.3	-1.6	-2.0	-1.3	-3.5	-0.4	-2.2	2.7	-2.3	-0.7	-0.7	-1.8
Systolic Blood Pressure	0.9	4.3	9.7	-2.4	-2.6	-2.5	-2.2	-1.8	-1.9	-2.4	-0.1	-2.5	-0.5	-1.6	-3.0	-2.5	0.4	-2.2	-1.7	-0.3	-1.8	-3.1	-2.6	-2.5	-1.9	0.6	-1.1	-2.7
Relative age of first facial hair	0.9	1.9	3.5	-1.9	-1.6	-0.2	-1.7	-1.7	-1.7	-1.9	-0.7	-1.8	-1.1	-1.0	-1.5	-1.5	-0.2	-1.2	-1.0	-0.8	-1.7	-1.3	-1.6	-1.1	-1.8	-0.9	-1.0	-1.8
Leg fat-free mass (left)	0.9	4.7	16.5	-2.1	-1.7	-4.0	0.2	-2.3	-2.0	-1.6	-2.9	-1.7	-1.9	-2.4	-4.1	-3.3	1.8	-1.7	0.3	3.4	-0.7	-0.0	-0.7	1.7	-1.9	2.4	-0.4	-2.2
Fed-up feelings	0.9	1.6	5.5	0.7	0.4	1.6	-0.4	0.5	0.4	0.7	2.3	0.6	1.7	2.3	1.7	1.6	-1.8	0.7	-1.1	-1.9	1.0	-1.0	-0.0	-1.5	0.6	-1.4	-0.7	0.8
Bilateral oophorectomy (both ovaries removed)	0.9	1.0	3.7	-1.1	-1.1	-1.1	-1.4	-1.1	-1.3	-1.3	0.4	-1.3	-0.5	0.1	-0.9	-0.8	-0.2	-0.5	-0.9	-1.1	-0.7	-0.7	-1.0	-0.0	-1.3	-1.3	-1.9	-1.2
Tinnitus: Yes, but not now, but have in the past	0.9	0.9	2.3	0.9	1.1	1.2	0.8	0.9	1.1	1.0	0.3	1.0	0.9	1.0	1.3	1.1	-0.9	1.5	0.3	0.8	1.0	1.4	0.5	0.4	1.1	0.6	0.1	0.9
Leg predicted mass (left)	0.9	4.9	17.1	-2.1	-1.7	-4.0	0.2	-2.3	-2.0	-1.6	-2.9	-1.8	-2.0	-2.5	-4.1	-3.4	1.8	-1.7	0.3	3.5	-0.8	0.0	-0.7	1.8	-1.9	2.5	-0.4	-2.2
Waist circumference	0.9	3.4	10.4	-1.5	-1.4	-2.6	0.3	-1.6	-1.4	-1.3	-2.6	-1.5	-1.5	-2.2	-3.2	-2.8	1.4	-1.3	0.6	3.2	-1.3	0.7	-0.6	2.2	-1.3	2.5	0.6	-1.8
Impedance of arm (right)	0.9	4.1	16.8	-1.2	-1.6	0.3	-2.9	-1.4	-1.5	-1.4	2.9	-1.3	-0.3	1.6	0.4	-0.3	-3.6	-0.2	-3.1	-4.1	-2.4	-1.1	-2.2	-0.9	-1.0	-3.8	-1.8	-1.0
Hip circumference	0.9	3.8	14.7	-1.4	-1.1	-1.6	0.7	-1.3	-1.1	-1.0	-3.6	-1.3	-2.1	-2.9	-3.5	-2.7	2.1	-1.3	1.2	3.8	-0.4	0.7	-0.0	1.0	-0.9	2.9	1.0	-1.6
Hair/balding pattern: Pattern 3	0.9	1.4	6.2	-0.8	-1.4	-0.8	-1.2	-1.3	-1.3	-0.9	-0.4	-0.8	-1.8	-0.6	0.2	-0.7	-1.1	-1.4	-0.9	-2.2	0.0	0.1	-0.5	-2.5	-1.0	-1.8	0.2	-0.4
Breastfed as a baby	0.9	1.1	4.7	-1.1	-1.4	-1.4	-0.7	-1.0	-1.1	-1.2	-1.0	-1.2	-1.0	-1.1	-0.7	-1.3	0.4	-2.2	0.0	-0.6	-0.6	-1.2	-0.4	-1.4	-1.0	0.6	0.9	-0.8
Gout (self-reported)	0.9	1.2	8.6	0.3	0.5	-0.3	1.2	0.3	0.4	0.5	-1.2	0.5	-0.3	-0.3	-0.7	0.1	2.5	0.7	1.4	1.9	0.1	1.6	1.1	2.9	0.3	0.5	0.3	0.3
High blood pressure (siblings)	0.9	1.3	4.0	-0.8	-1.1	-1.5	-1.3	-0.8	-0.8	-0.7	1.3	-0.7	1.9	0.9	-0.2	-0.3	-1.4	-0.3	-1.4	-2.0	-0.8	-1.5	-1.2	-0.7	-0.9	-1.4	-1.2	-0.7
Wheeze or whistling in the chest in last year	0.9	1.7	5.7	1.2	1.5	0.9	1.8	1.3	1.3	1.4	-0.2	1.2	2.4	0.2	0.2	0.8	0.5	1.1	1.3	2.1	0.7	1.2	1.2	1.4	1.5	1.8	1.1	1.0
Number of children fathered	0.9	1.0	3.4	1.0	1.1	0.4	1.1	1.2	1.2	0.9	-0.3	0.9	0.5	-0.0	-0.1	0.4	0.7	0.8	1.2	1.8	1.3	1.6	1.0	0.8	1.1	1.5	0.4	0.8
Age at first live birth	0.9	1.5	8.1	-0.1	-0.2	-0.1	-1.3	-0.1	-0.1	-0.1	1.9	0.1	0.9	1.4	-0.1	0.9	-2.9	0.5	-1.7	-2.5	-0.7	-2.0	-1.3	-1.5	-0.2	-1.6	-1.0	0.0
Emphysema/chronic bronchitis	0.9	1.0	3.7	-0.9	-0.5	-1.3	-1.3	-0.4	-0.4	-0.8	1.0	-0.9	0.5	-0.1	-0.6	-0.1	-1.4	-0.3	-1.5	-0.3	-1.6	-1.9	-1.7	-1.0	-0.4	-0.1	-1.1	-1.3
Migraine (self-reported)	0.9	1.1	8.5	-1.1	-1.0	-0.7	-0.7	-1.2	-1.1	-0.9	0.0	-0.8	-2.9	-0.7	-1.3	-1.6	1.0	-1.1	-0.7	-0.2	-1.1	-1.0	-0.8	0.5	-1.1	-0.3	-0.2	-0.9
Medication: Allopurinol	0.9	1.2	6.8	1.0	1.1	0.9	1.3	0.8	1.0	1.2	0.3	1.2	0.6	1.1	-0.1	1.0	1.4	1.7	0.8	1.0	0.6	1.2	1.3	2.6	0.7	-0.8	-0.6	0.9
Illnesses of siblings: Diabetes	0.9	1.1	3.6	0.7	0.7	0.2	1.6	0.3	0.4	0.7	-1.3	0.8	-1.1	-0.2	-0.4	0.1	1.2	-0.1	1.7	1.4	0.8	1.2	1.6	1.9	0.7	1.2	1.6	0.8
Smoking status: Previous	0.9	1.3	3.4	-1.3	-1.0	-1.5	-1.6	-0.8	-1.0	-1.4	0.4	-1.6	-0.1	-1.0	-0.1	-0.6	-0.1	-1.4	-1.3	-0.3	-1.8	-1.2	-1.8	-0.3	-1.1	0.3	-1.1	-1.7
Ever had bowel cancer screening	0.9	1.0	3.8	-0.7	-0.7	-1.3	-1.1	-0.6	-0.6	-0.7	1.0	-0.9	1.5	0.2	0.2	-0.2	-2.0	-0.4	-1.4	-1.2	-0.5	-1.3	-1.3	-1.6	-0.7	-0.5	-1.2	-0.9
Alzheimer’s Disease (including proxy)	0.8	1.2	5.6	1.0	1.0	0.6	0.4	1.2	1.1	1.0	1.7	1.0	2.4	1.4	0.6	1.4	-0.4	1.4	-0.2	-0.3	-0.4	0.3	0.3	2.2	1.0	-0.3	-0.6	0.6
Rheumatoid Arthritis	0.8	1.1	6.1	0.1	0.0	0.1	1.1	0.2	0.2	0.1	-1.9	-0.0	-0.5	-0.8	0.1	-0.5	2.5	-0.3	1.7	1.9	0.1	0.0	0.9	2.2	0.2	1.7	1.1	0.1
Respiratory disease	0.8	1.7	3.7	-1.5	-1.3	-1.8	-1.7	-1.3	-0.9	-1.3	1.2	-1.3	0.5	-0.5	-0.1	-0.9	-1.0	-1.2	-1.9	-0.9	-1.3	-1.3	-1.8	-1.3	-1.2	-1.3	-1.7	-1.5
Lung FVC	0.8	4.1	15.4	-2.3	-2.6	-3.9	-1.7	-2.6	-2.8	-2.4	-1.2	-2.4	-3.0	-1.3	-2.5	-1.8	0.5	-1.9	-1.0	-0.2	-0.9	-1.0	-1.5	-0.9	-2.5	-0.7	-1.5	-2.2
Multivitamins +/- minerals	0.8	1.1	4.9	0.1	0.1	-0.1	-0.8	0.0	0.1	0.1	2.0	0.1	1.1	1.1	1.3	0.4	-2.0	0.1	-1.5	-1.8	-0.1	-0.7	-0.5	-1.3	0.2	-2.2	-0.7	0.2
Hearing difficulty/problems with background noise	0.8	1.3	3.5	1.2	0.8	1.7	0.0	1.0	1.1	1.2	1.2	1.4	0.8	1.5	1.8	1.5	-1.0	1.0	-0.2	-1.9	0.3	1.0	0.6	0.1	1.1	-1.6	0.2	1.4
Fluid intelligence score	0.8	1.8	8.9	1.1	0.7	0.9	1.6	1.0	1.1	1.0	-1.4	0.9	-1.1	-0.5	1.5	0.2	0.2	0.0	1.9	1.1	1.1	1.7	1.6	-0.3	1.5	1.9	3.0	1.4
Medication: Lansoprazole	0.8	0.9	2.8	-1.0	-0.9	-1.2	-0.4	-1.0	-1.2	-0.9	-0.5	-1.0	-1.4	-0.1	-1.7	-1.5	1.1	-1.0	-0.4	0.7	-0.9	-1.0	-0.7	0.9	-1.1	0.2	-0.7	-1.1
Hair/balding pattern: Pattern 4	0.8	2.0	5.1	-1.9	-2.0	-2.0	-1.5	-1.7	-1.6	-1.8	0.2	-1.7	-0.7	-0.7	-2.3	-1.4	0.0	-1.5	-1.4	0.4	-1.0	-1.2	-1.6	-0.4	-1.4	0.4	-1.2	-2.0
Qualifications: O levels/GCSEs or equivalent	0.8	1.3	6.0	0.6	0.6	1.4	1.5	0.2	0.4	0.8	-1.3	0.8	-1.2	-0.2	0.5	-0.1	1.3	0.2	1.5	1.3	0.1	1.8	1.3	2.5	0.6	1.6	1.9	0.9
Heart disease (mother)	0.8	0.9	2.5	-0.9	-0.8	-1.2	-0.5	-0.7	-0.7	-0.9	-1.2	-1.0	0.3	-1.5	-1.5	-1.1	1.0	-0.9	-0.2	0.8	-1.6	0.1	-1.0	0.7	-0.8	1.1	0.0	-1.2
Pulse rate, automated reading	0.8	2.6	5.5	1.9	2.0	2.2	1.6	2.2	2.1	1.9	0.7	1.8	1.2	1.1	1.2	2.1	-1.0	1.4	1.0	1.3	1.7	1.0	1.1	-0.6	2.4	1.7	1.6	1.5
Number of full sisters	0.8	0.9	4.0	0.1	-0.1	0.3	1.0	-0.3	-0.4	0.1	-1.2	0.1	-0.6	-0.8	-0.3	-1.0	1.8	-0.5	1.2	1.4	0.3	2.0	0.9	1.8	-0.1	1.5	0.9	0.2
Suffer from ‘nerves’	0.8	1.2	3.6	-1.0	-1.3	-1.9	-1.6	-0.8	-0.9	-1.1	0.8	-1.1	-0.8	0.2	-0.4	-0.2	-1.0	-1.1	-1.4	-1.5	-0.9	-1.1	-1.4	-1.8	-0.8	-0.6	-0.8	-1.0
Tinnitus: Yes, now most or all of the time	0.8	1.0	5.6	0.6	0.4	0.1	1.2	0.3	0.3	0.6	-1.7	0.8	-0.1	0.0	0.6	-0.0	2.4	0.3	1.6	1.1	1.2	1.2	1.7	1.1	0.3	-0.2	0.7	0.8
Number of operations (self-reported)	0.8	1.2	6.4	-1.2	-1.4	-2.5	-0.9	-1.3	-1.4	-1.3	-0.5	-1.3	-0.3	-0.9	-0.5	-1.2	-0.0	-1.4	-0.4	-0.6	-1.3	-1.1	-0.9	-0.8	-1.3	-0.1	-0.2	-1.2
Average weekly beer plus cider intake	0.8	1.2	4.4	-1.2	-0.9	-0.4	-0.5	-0.9	-0.8	-1.1	-2.1	-1.2	-1.0	-1.8	-1.5	-1.3	1.3	-1.0	0.4	1.3	-0.8	0.7	-0.7	-0.6	-0.8	1.2	0.2	-1.3
Alzheimer’s Disease (in father)	0.7	0.7	3.7	1.0	0.8	0.1	0.7	0.8	0.6	0.8	0.4	1.0	1.9	1.3	0.3	1.2	-0.3	1.0	0.6	-0.1	0.5	-0.0	1.0	1.3	0.8	-0.3	0.2	0.9
Type 2 Diabetes (T2D) (2018)	0.7	1.4	7.2	0.9	1.1	0.1	1.8	0.9	1.0	1.0	-0.5	1.1	0.6	0.5	0.1	0.4	0.9	0.7	1.3	2.1	0.6	0.0	1.1	2.2	0.8	2.7	1.0	0.9
Ever had hysterectomy (womb removed)	0.7	0.8	3.4	-0.9	-0.6	-0.7	-1.2	-0.5	-0.6	-0.8	1.0	-0.9	1.2	-0.1	-0.1	-0.2	-0.6	-0.5	-1.2	-0.3	0.0	-1.5	-1.1	-1.3	-0.7	-0.7	-1.9	-1.1
Systolic blood pressure, automated reading	0.7	2.0	7.3	-1.4	-1.7	-2.7	-1.3	-0.8	-1.0	-1.5	-0.2	-1.6	-0.0	-1.0	-2.2	-1.3	0.1	-1.2	-1.0	0.1	-0.9	-2.7	-1.6	-1.8	-1.1	0.4	-0.9	-1.8
Eye problems/disorders: Diabetes related eye disease	0.7	0.8	4.4	0.7	1.0	0.1	1.1	1.0	0.9	0.8	-0.0	0.6	0.8	0.2	0.4	0.9	-0.2	0.8	0.9	1.5	0.2	0.5	0.5	1.4	0.9	2.1	0.6	0.5
Medication for hormone replacement therapy	0.7	0.8	2.3	-0.9	-0.9	-1.0	-0.6	-1.0	-1.1	-0.9	0.2	-0.9	-1.5	-0.1	-1.5	-1.1	-0.3	-0.4	-0.6	-0.3	-0.9	-1.1	-0.7	0.6	-0.9	-0.8	-0.6	-0.9
Pack years adult smoking proportion	0.7	1.0	7.2	-1.1	-0.8	-0.5	-0.6	-0.9	-0.9	-1.2	-1.2	-1.2	-0.1	-1.3	-2.7	-1.1	1.0	-0.8	-0.0	0.8	-0.9	0.3	-0.7	0.4	-1.1	0.3	-0.5	-1.2
Had other major operations	0.7	0.8	5.0	-0.9	-0.7	-1.0	-0.9	-0.7	-0.5	-0.8	0.2	-0.8	0.1	-1.0	-0.6	-0.3	-0.4	-0.8	-0.9	-0.9	-0.7	-1.7	-1.0	-2.2	-0.9	-0.8	-0.7	-0.9
Health satisfaction	0.7	0.9	2.7	1.2	0.8	1.0	0.9	1.2	1.0	1.1	0.2	1.2	0.6	0.7	1.5	0.6	0.4	0.5	0.7	0.1	1.6	1.4	1.2	-0.3	1.2	0.2	0.6	1.2
Medication for pain relief, constipation, heartburn	0.7	1.2	3.9	-1.0	-0.8	-1.2	0.1	-0.8	-0.8	-1.0	-1.7	-1.0	-0.8	-1.8	-1.1	-0.8	2.0	-0.9	0.6	1.5	-1.1	-0.6	-0.4	0.9	-1.0	1.4	0.6	-0.9
Medication: Seretide 50 evohaler	0.7	0.8	3.7	-0.6	-0.2	-0.2	0.3	-0.4	-0.1	-0.4	-1.3	-0.5	-0.9	-1.1	-0.8	-0.7	1.9	-0.2	0.5	1.9	-1.4	-0.1	-0.4	0.9	-0.5	1.5	0.3	-0.8
Whole body fat mass	0.7	2.8	14.0	-1.7	-1.4	-2.4	-0.1	-1.6	-1.5	-1.4	-1.9	-1.6	-1.1	-1.8	-3.7	-2.5	0.4	-1.0	-0.0	2.9	-1.4	0.2	-0.9	1.7	-1.3	1.5	-0.1	-2.0
Supplements: Vitamin C	0.7	0.8	4.8	0.1	0.5	0.1	-0.4	0.2	0.2	0.2	1.6	0.2	0.1	1.6	0.0	0.5	-0.3	1.2	-0.8	-0.5	0.1	-1.5	-0.4	0.4	-0.2	-1.8	-2.2	-0.1
Leg fat-free mass (right)	0.7	3.8	14.7	-1.8	-1.5	-3.7	0.2	-2.1	-1.8	-1.3	-2.4	-1.4	-1.4	-1.9	-3.8	-2.9	1.7	-1.4	0.2	3.1	-0.6	-0.4	-0.6	1.6	-1.8	2.1	-0.7	-1.9
Leg predicted mass (right)	0.7	3.8	14.3	-1.8	-1.4	-3.7	0.3	-2.0	-1.8	-1.3	-2.4	-1.4	-1.4	-1.9	-3.8	-2.9	1.8	-1.3	0.3	3.2	-0.6	-0.3	-0.5	1.7	-1.7	2.2	-0.6	-1.9
Commuting to job workplace: Public transport	0.7	0.8	3.8	0.4	0.8	0.9	-0.3	0.4	0.6	0.6	1.9	0.6	0.6	0.9	0.9	1.0	-1.4	0.7	-1.2	-1.1	0.0	-1.2	-0.3	-1.2	0.6	-0.9	-0.5	0.4
Age started oral contraceptive pill	0.7	0.9	2.2	1.1	1.1	1.4	0.7	1.0	1.0	1.2	0.6	1.2	0.5	1.3	1.5	1.3	-0.9	1.2	0.4	-0.3	1.0	-0.7	0.7	-0.4	1.0	0.2	0.4	1.1
Commuting to job workplace: Cycle	0.7	0.8	3.1	0.8	0.5	0.5	0.8	0.5	0.7	0.8	-0.8	0.9	0.3	0.9	0.9	0.1	0.0	0.8	1.2	-0.5	1.8	1.0	1.6	-0.6	0.7	-1.6	0.5	1.1
Ovarian Cancer	0.6	0.8	4.1	0.5	0.9	0.2	-0.2	0.8	0.9	0.5	2.0	0.3	1.2	1.1	0.3	1.2	-1.3	1.2	-0.8	-0.3	-0.2	0.3	-0.3	0.7	0.7	-1.3	-1.0	0.2
Type 2 Diabetes (T2D) (2012)	0.6	0.7	3.0	-1.0	-1.0	-1.7	-0.6	-1.2	-1.0	-1.0	0.3	-0.8	-0.1	-0.1	-1.4	-1.1	0.1	-0.3	-0.8	-0.0	-0.1	0.0	-1.0	0.3	-1.2	-0.4	-1.2	-0.9
Trunk fat percentage	0.6	2.4	12.7	-1.8	-1.6	-2.0	-1.1	-1.6	-1.6	-1.6	-0.6	-1.8	-0.9	-1.2	-3.6	-1.9	-1.1	-0.7	-1.1	1.3	-1.9	-0.6	-1.6	0.9	-1.5	0.0	-0.9	-2.1
Frequency of unenthusiasm / disinterest in last 2 weeks	0.6	0.8	3.2	0.7	0.7	0.4	0.0	0.8	1.0	0.8	1.5	0.7	0.8	1.2	1.2	1.1	-1.8	0.8	-0.6	-0.7	0.7	0.8	0.0	-1.2	1.1	-0.3	-0.1	0.6
Body mass index (BMI)	0.6	2.7	18.6	0.7	1.0	-1.0	2.3	0.9	1.0	1.1	-2.3	0.9	0.6	-1.0	-2.1	-0.2	1.5	0.8	2.1	4.3	1.7	1.1	1.5	1.2	0.9	3.1	1.1	0.3
Hayfever/allergic rhinitis (self-reported)	0.6	0.7	2.0	0.9	0.9	1.3	0.4	0.9	0.7	0.9	0.6	1.0	1.4	0.6	1.0	0.9	-0.4	0.8	0.2	-0.8	1.4	-0.3	0.8	-1.1	0.7	-0.8	-0.3	1.0
Glaucoma (self-reported)	0.6	0.7	3.0	-0.7	-0.8	0.3	0.4	-0.9	-1.0	-0.7	-1.7	-0.9	-0.3	-0.8	-0.7	-1.6	0.3	-0.9	1.2	0.7	-0.5	0.4	0.7	1.2	-0.6	0.3	1.3	-0.3
Leg fat mass (right)	0.6	2.4	10.9	-1.2	-0.8	-1.6	0.5	-1.2	-1.0	-0.9	-2.3	-1.1	-1.0	-1.9	-3.3	-2.2	1.1	-0.7	0.6	3.3	-0.7	0.6	-0.4	1.7	-0.9	2.0	0.4	-1.5
Had major operations	0.6	0.7	2.7	-0.7	-1.2	-1.6	-0.5	-0.7	-0.9	-0.9	-0.8	-1.0	-1.4	-0.9	-0.1	-1.0	-0.5	-1.5	0.2	-0.4	-0.9	-0.2	-0.2	-0.2	-0.6	0.3	1.1	-0.5
Age at last live birth	0.6	0.9	3.4	-0.1	0.0	0.1	-1.1	0.0	-0.1	-0.2	1.6	-0.1	1.0	0.6	-0.3	0.7	-1.8	0.4	-1.6	-1.4	-1.3	-1.2	-1.4	-0.5	-0.2	-1.2	-0.9	-0.3
Commuting to job workplace: Walk	0.6	0.6	5.4	-0.4	-0.1	0.6	-0.8	-0.3	-0.4	-0.4	0.7	-0.3	-0.4	-0.2	-0.1	0.2	-1.1	-0.6	-1.1	-1.1	-0.4	-1.6	-0.8	-2.3	-0.3	-0.3	-0.3	-0.7
Osteoarthritis (self-reported)	0.6	0.7	2.4	0.8	0.9	0.2	1.1	0.8	0.6	0.7	-0.6	0.7	1.5	0.4	0.9	0.4	0.3	0.4	1.1	0.9	1.2	1.6	1.3	0.7	0.8	0.2	0.5	0.7
Medication: Aspirin	0.6	0.8	3.0	-0.7	-0.7	-1.7	-1.0	-0.6	-0.5	-0.6	1.5	-0.5	0.4	0.3	-0.6	-0.5	-0.7	-0.6	-1.5	-1.2	-1.0	-1.4	-1.1	-0.2	-0.7	-0.6	-1.1	-0.7
Leg fat mass (left)	0.6	2.3	11.7	-1.1	-0.7	-1.5	0.6	-1.1	-0.9	-0.8	-2.3	-1.0	-0.7	-1.8	-3.2	-2.0	1.1	-0.6	0.7	3.4	-0.7	0.4	-0.3	1.7	-0.9	2.1	0.4	-1.4
Alzheimer’s Disease (in mother)	0.5	0.5	1.7	-0.6	-0.6	-0.6	-1.0	-0.5	-0.5	-0.6	1.1	-0.6	0.3	0.2	-0.2	-0.4	-0.3	-0.3	-1.1	-0.9	-1.3	-0.3	-1.1	0.9	-0.6	-0.4	-1.2	-0.7
Irritable Bowel Disease (IBD)	0.5	1.3	4.7	-1.4	-1.1	-1.1	-1.3	-1.3	-1.1	-1.2	-0.1	-1.2	-0.7	-0.8	-0.5	-0.7	-1.3	-1.0	-1.2	-0.8	-1.2	-1.1	-1.1	-1.0	-1.4	-2.2	-0.9	-1.2
Verbal and Numeric Reasoning (VNR)	0.5	1.1	4.0	0.7	0.4	0.7	1.0	0.9	0.9	0.5	-1.3	0.5	-1.6	-1.2	0.7	0.2	1.4	-0.3	1.6	1.0	0.8	1.6	1.2	-0.2	1.0	1.3	2.0	0.8
Breast Cancer	0.5	1.3	5.7	-0.7	-0.8	0.7	-0.1	-0.8	-1.0	-0.9	-1.5	-1.0	-2.4	-1.7	-1.2	-0.8	0.4	-1.9	0.7	0.3	-0.8	1.1	-0.2	-0.2	-0.4	1.7	2.2	-0.4
HDL Cholesterol	0.5	0.8	3.7	0.3	0.0	1.6	-0.8	0.1	0.3	0.2	1.0	0.4	0.8	0.6	0.8	0.5	-1.4	-0.1	-1.0	-1.9	0.3	-0.8	-0.2	-1.6	0.0	-1.8	-0.5	0.6
Schizophrenia (2014)	0.5	1.0	5.3	-0.4	-0.4	1.3	-1.1	-0.6	-0.9	-0.4	1.2	-0.4	-1.0	0.8	0.8	-0.2	-1.3	-0.1	-1.3	-2.0	-0.2	0.0	-0.7	-1.2	-0.7	-2.3	-1.4	-0.4
Triglycerides	0.5	0.8	3.3	-0.8	-0.6	-1.3	-0.6	-0.6	-0.7	-0.8	-0.1	-0.8	-0.3	-0.3	-1.5	-0.6	0.7	-0.0	-0.6	0.6	-0.7	-1.2	-0.5	1.0	-1.0	-1.8	-1.3	-1.1
Smoking Status	0.5	1.2	4.3	0.6	1.1	1.0	1.1	0.9	0.9	0.5	-0.9	0.5	1.3	-0.5	0.6	0.3	0.6	0.2	1.5	1.5	0.0	1.7	0.8	2.1	0.9	2.0	1.6	0.5
Chronotype (morning person)	0.5	1.2	4.2	1.3	1.1	0.6	0.8	1.6	1.4	1.0	-0.0	0.9	0.4	0.1	2.0	1.9	-0.2	0.2	0.8	0.1	1.1	1.2	1.0	-0.5	1.6	1.3	1.5	1.2
Hand grip strength (left)	0.5	1.4	3.3	-1.4	-1.6	-1.8	-0.7	-1.5	-1.6	-1.3	-1.4	-1.4	-1.3	-0.7	-1.5	-1.4	1.0	-1.0	-0.3	0.5	-1.0	-1.0	-1.1	0.4	-1.5	0.4	-0.6	-1.3
Frequency of depressed mood in last 2 weeks	0.5	0.7	7.0	-0.1	-0.2	-0.0	-0.7	0.0	0.2	0.0	0.9	0.0	-0.2	0.7	1.1	0.4	-1.8	-0.3	-1.0	-1.3	0.6	-0.4	-0.4	-2.6	0.2	-0.9	-0.4	0.0
Diabetes (mother)	0.5	0.7	2.6	0.5	0.7	0.6	-0.3	0.9	0.7	0.4	1.3	0.5	0.9	1.0	-0.8	1.6	-0.1	1.1	-0.5	-0.4	0.3	-1.4	-0.4	-0.8	0.2	-0.1	-1.6	0.1
Hayfever, allergic rhinitis or eczema	0.5	1.2	6.5	1.0	1.2	2.5	0.8	1.0	1.0	1.1	-0.1	1.2	0.6	0.1	1.4	0.5	0.3	0.6	0.9	-0.0	2.2	-0.1	1.3	-1.6	1.0	0.2	0.4	1.2
Stomach or abdominal pain in last month	0.5	0.6	2.7	-0.0	-0.1	0.4	0.6	0.2	0.2	-0.1	-1.1	-0.0	-0.4	-1.2	0.7	-0.8	1.6	-1.1	1.1	1.2	0.4	0.7	0.8	0.3	0.2	1.6	1.1	0.0
Medication: Atenolol	0.5	0.6	3.1	0.8	0.7	-0.2	0.7	1.1	1.1	0.7	0.0	0.8	0.7	-0.1	0.1	0.4	0.4	0.5	0.6	1.2	0.8	1.0	0.4	0.7	0.9	1.8	0.6	0.5
Illnesses of siblings	0.5	0.7	2.4	0.9	1.0	1.5	0.5	1.0	0.9	0.8	0.1	0.8	-0.6	0.4	0.7	1.0	-0.4	0.8	0.5	-0.1	1.3	0.5	0.8	-1.0	0.9	-0.3	0.2	1.0
Father’s age at death	0.5	0.7	2.1	0.7	0.7	1.4	0.1	0.2	0.3	0.8	1.4	0.9	0.8	1.5	1.1	0.9	-1.0	1.1	-0.6	-0.7	0.8	-0.5	0.0	-0.2	0.3	-0.4	-0.6	0.7
Asthma	0.5	0.9	2.1	-1.0	-0.9	-1.3	-1.4	-0.6	-0.6	-1.0	1.0	-1.0	0.2	-0.7	-0.4	-0.4	-0.3	-1.1	-1.5	-0.5	-1.0	-0.9	-1.3	-0.9	-0.8	-1.0	-1.3	-1.2
Illnesses of mother	0.5	0.7	4.2	-0.9	-0.9	-0.7	-0.6	-1.0	-0.6	-0.8	-0.5	-0.7	-2.1	-1.0	-0.1	-1.2	-0.5	-1.1	-0.2	-0.8	-0.1	0.7	-0.2	-0.8	-0.6	-0.8	0.3	-0.4
Peak expiratory flow (PEF)	0.5	1.1	4.1	-0.9	-0.8	-1.2	-0.2	-1.1	-1.2	-0.9	-2.0	-1.0	-1.3	-1.1	-2.0	-1.6	0.9	-0.7	0.4	0.9	0.3	0.6	-0.3	-0.9	-1.0	0.5	-0.4	-1.0
Medication: Paracetamol	0.5	0.9	2.8	1.1	1.1	1.5	0.8	0.9	0.8	1.1	-0.0	1.2	-0.1	1.0	1.1	0.4	-0.5	0.9	0.7	0.0	0.6	1.7	1.0	1.1	1.1	0.0	0.6	1.2
Alcohol intake frequency.	0.5	1.2	3.2	-1.2	-1.3	-0.6	-1.2	-1.4	-1.6	-1.2	0.8	-1.3	0.3	0.7	-1.8	-0.7	-1.3	-0.6	-1.4	-0.4	-0.9	-1.2	-1.3	-0.2	-1.2	-0.9	-1.1	-1.4
Leg pain on walking	0.5	0.6	2.5	0.9	0.9	0.6	0.7	0.9	0.8	0.8	0.5	0.8	0.9	0.9	0.2	0.9	-0.3	1.0	0.4	0.5	1.6	1.0	1.0	-0.3	1.0	-0.5	-0.3	0.6
Average weekly red wine intake	0.5	0.8	3.2	0.7	0.8	-0.2	1.0	0.6	0.8	0.8	-0.6	0.9	-1.3	-0.4	0.4	0.1	0.7	0.1	0.7	0.9	-0.6	0.8	0.6	1.8	0.7	1.7	1.5	0.7
Medication for cholesterol	0.5	0.8	2.3	1.0	1.0	1.5	0.6	1.3	1.1	0.7	-0.1	0.6	0.1	0.3	1.3	0.8	0.2	0.7	1.1	0.2	0.7	1.4	1.1	0.7	0.9	0.2	0.5	0.9
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.5	0.5	3.1	-0.5	-0.5	-0.7	-0.7	-0.5	-0.6	-0.6	0.2	-0.7	-1.5	-0.2	-0.6	-0.3	-0.3	-0.7	-0.8	-0.3	-0.3	-1.1	-0.9	-1.8	-0.6	0.4	-0.4	-0.8
Asthma (self-reported)	0.5	1.1	2.5	-1.1	-1.0	-1.4	-1.5	-0.8	-0.7	-1.1	1.1	-1.1	0.3	-0.7	-0.5	-0.5	-0.3	-1.1	-1.6	-0.6	-1.1	-1.2	-1.4	-0.8	-1.0	-1.1	-1.4	-1.2
Arm fat mass (left)	0.5	1.9	11.9	-0.6	-0.3	-1.9	1.0	-0.6	-0.5	-0.3	-2.1	-0.5	-0.3	-1.3	-2.9	-1.6	0.9	-0.2	1.0	3.4	-0.0	0.7	0.2	1.7	-0.4	2.2	0.5	-0.9
Average weekly champagne plus white wine intake	0.5	0.7	2.8	0.4	0.0	-0.2	-0.4	0.2	0.1	0.3	1.0	0.4	1.2	1.1	1.4	0.5	-1.7	0.5	-0.5	-1.4	1.0	-0.8	-0.0	-1.5	0.3	-0.9	-0.2	0.5
Irritability	0.5	0.8	3.8	-0.8	-1.0	0.3	-0.7	-0.7	-0.6	-0.9	-0.7	-0.9	-1.8	-0.9	-0.3	-0.2	0.1	-1.5	-0.2	-0.9	0.0	0.1	0.2	-1.9	-0.6	-1.8	0.3	-0.5
Unable to work because of sickness or disability	0.5	0.6	3.2	-0.8	-0.8	-0.5	-0.9	-0.7	-0.6	-0.7	0.2	-0.8	0.2	-0.5	-1.0	-0.7	-1.1	-0.7	-0.9	-0.6	-1.8	0.1	-1.1	0.4	-0.5	-0.2	0.5	-0.8
Pain experienced in last month	0.5	0.9	3.5	0.3	0.3	0.3	-0.4	0.2	0.2	0.4	1.4	0.3	1.0	0.9	-0.4	0.9	-1.4	1.1	-1.0	-1.3	0.7	-1.3	-0.4	-1.7	-0.1	-1.9	-1.5	0.3
Deep venous thrombosis (DVT) (self-reported)	0.5	0.7	1.7	0.9	1.2	0.1	1.1	0.9	1.2	1.1	-0.0	1.2	0.0	0.2	1.3	0.4	-0.0	0.6	0.3	0.9	0.5	0.6	0.5	-0.0	1.1	1.1	1.2	0.8
Pack years of smoking	0.5	0.7	5.1	-1.0	-0.8	-0.4	-0.7	-0.8	-0.9	-1.1	-0.8	-1.1	-0.3	-1.0	-2.3	-0.9	0.6	-0.7	-0.3	0.3	-0.8	0.3	-0.7	0.1	-1.0	-0.1	-0.6	-1.0
Schizophrenia vs Biploar Disorder	0.4	0.6	3.6	0.6	0.6	1.9	0.0	0.4	0.1	0.5	0.7	0.4	0.0	1.4	-0.2	0.7	-1.6	1.4	-0.3	-0.7	0.4	0.0	-0.0	-0.3	0.3	-0.8	-0.5	0.4
Angina	0.4	0.5	1.9	-0.5	-0.5	-1.4	-0.2	-0.3	-0.5	-0.6	-0.5	-0.5	0.9	-0.8	-1.0	-0.8	1.1	-0.5	-0.0	0.6	-1.0	-0.4	-0.5	1.1	-0.6	0.6	-0.3	-0.7
Mouth/teeth dental problems	0.4	0.7	2.9	-0.9	-0.7	-0.6	-0.8	-0.8	-0.8	-0.8	-1.2	-0.8	-0.8	-1.1	-1.7	-0.4	-0.4	-0.1	-0.5	-0.4	-1.3	-0.3	-1.2	-0.6	-0.8	-0.3	-0.3	-0.9
Diabetes (self-reported)	0.4	0.5	2.6	-0.5	-0.7	-1.2	0.2	-0.5	-0.3	-0.5	-0.4	-0.3	-0.9	-0.5	-0.6	-0.8	0.7	-1.3	0.1	0.7	-0.7	-0.8	-0.1	1.1	-0.4	1.6	0.7	-0.3
Qualifications: A levels/AS levels or equivalent	0.4	0.8	3.2	0.9	0.6	1.3	0.6	0.4	0.4	0.7	-0.1	0.9	-0.9	0.3	1.5	0.5	-0.1	0.5	0.7	-1.0	1.8	0.3	1.5	-1.0	0.4	-1.8	0.4	1.1
Medication: Ibuprofen (e.g. Nurofen)	0.4	0.6	2.5	0.6	0.6	1.6	0.5	0.6	0.7	0.6	0.0	0.6	0.0	0.4	0.7	0.2	-0.0	0.4	0.6	-0.1	1.6	1.4	1.0	-0.9	0.7	-0.6	0.2	0.7
Arm fat mass (right)	0.4	1.8	11.2	-0.6	-0.4	-2.0	0.9	-0.6	-0.5	-0.3	-2.1	-0.5	-0.4	-1.4	-3.0	-1.6	0.8	-0.2	0.9	3.3	0.0	0.7	0.1	1.4	-0.4	2.1	0.3	-1.0
Length of working week for main job	0.4	0.4	2.6	0.2	0.2	-0.3	0.6	0.4	0.1	0.2	-1.3	0.1	0.8	-0.7	-0.7	0.3	0.4	-0.2	0.8	1.6	0.4	-0.1	0.4	-0.2	0.3	1.3	0.7	-0.1
Mouth/teeth dental problems: Bleeding gums	0.4	0.5	1.8	0.7	0.9	-0.2	0.9	0.9	0.7	0.7	0.4	0.6	1.3	0.6	0.6	0.5	0.3	0.5	0.8	1.2	0.8	0.4	0.9	0.6	0.9	1.0	0.5	0.5
Blood clot in the leg (DVT)	0.4	0.6	1.6	0.8	1.2	-0.0	1.0	0.8	1.1	1.0	0.1	1.1	-0.0	0.2	1.3	0.5	-0.1	0.5	0.2	0.7	0.6	0.6	0.4	-0.3	1.1	1.0	1.0	0.7
Chronic bronchitis/emphysema (mother)	0.4	0.5	3.9	-0.4	0.1	0.5	0.3	-0.1	-0.0	-0.2	-1.0	-0.4	-0.1	-0.9	0.1	-0.6	0.8	-0.3	0.4	2.0	-0.5	0.1	-0.4	0.1	0.0	1.8	0.4	-0.8
Leg fat percentage (right)	0.4	1.3	8.9	-0.4	-0.1	0.0	0.8	-0.2	-0.2	-0.2	-2.1	-0.5	-0.4	-1.5	-2.0	-1.3	0.8	-0.1	1.0	3.0	-0.4	1.0	0.1	1.5	-0.1	1.6	1.0	-0.7
Seen a psychiatrist for nerves, anxiety, tension or depression	0.4	0.5	2.3	0.5	0.5	0.4	-0.2	0.9	0.9	0.5	1.1	0.6	-0.0	1.0	0.6	1.0	-1.5	0.6	-0.5	-0.5	0.7	-0.1	-0.0	-1.2	0.9	-0.7	-0.5	0.5
Angina (self-reported)	0.4	0.5	1.8	-0.5	-0.5	-1.3	-0.3	-0.3	-0.5	-0.7	-0.6	-0.6	0.9	-0.9	-0.9	-0.8	1.0	-0.6	-0.0	0.5	-1.0	-0.2	-0.6	1.0	-0.6	0.7	-0.1	-0.7
Chest pain or discomfort	0.4	0.5	3.9	0.0	0.0	-0.1	0.4	0.2	0.2	-0.1	-1.1	0.0	-0.1	-0.9	-0.1	-0.6	0.1	-0.5	0.9	1.5	-0.2	0.9	0.3	0.5	0.5	2.0	1.5	-0.2
Commuting to job workplace: Car/motor vehicle	0.4	0.4	3.3	-0.1	-0.6	-0.6	0.3	-0.2	-0.6	-0.4	-0.7	-0.5	-0.5	0.0	-0.5	-0.4	1.3	-0.6	0.9	0.9	-0.1	0.3	0.5	1.8	-0.4	0.7	0.2	-0.1
Medication: Aspirin	0.4	0.6	2.4	-0.6	-0.8	-1.5	-0.8	-0.7	-0.6	-0.6	1.0	-0.5	0.4	0.3	-0.8	-0.6	-0.2	-0.6	-1.0	-0.9	-0.7	-1.3	-0.7	0.1	-0.7	-0.4	-0.9	-0.6
Diabetes diagnosed by doctor	0.4	0.7	4.6	-0.1	-0.2	-0.6	0.8	-0.1	0.1	-0.0	-0.7	0.2	-0.4	-0.5	-0.7	-0.6	1.6	-0.8	0.7	1.4	-0.1	-0.1	0.4	1.8	-0.1	2.1	0.9	0.1
Mouth/teeth dental problems: Mouth ulcers	0.4	0.6	3.2	-0.2	-0.1	-0.2	-0.8	0.1	0.0	-0.3	1.6	-0.3	0.6	0.6	-0.1	0.1	-0.8	-0.2	-1.0	-0.8	0.4	-1.2	-0.2	-1.1	-0.2	-1.8	-1.4	-0.4
Medication: Paracetamol	0.4	0.7	1.5	0.9	0.9	1.2	0.7	0.7	0.8	1.0	0.1	1.1	0.2	1.0	1.0	0.4	-0.4	0.7	0.6	0.1	0.4	1.2	0.7	1.2	1.0	0.7	0.5	1.0
Illnesses of father: High blood pressure	0.4	0.5	5.3	0.2	-0.0	0.4	-0.2	0.2	0.1	0.1	0.3	0.1	-0.8	-0.2	0.6	0.1	-0.5	-0.3	-0.2	-0.6	1.2	-1.4	0.3	-2.3	0.1	-0.6	-0.2	0.2
Ever smoked	0.4	0.7	1.8	-1.0	-0.4	-0.6	-1.0	-0.3	-0.4	-1.1	0.1	-1.2	-0.6	-1.4	-0.7	-0.6	0.8	-1.3	-0.5	0.5	-1.1	-0.6	-0.8	0.4	-0.6	-0.3	-0.9	-1.3
Risk taking	0.4	0.6	3.2	0.0	0.5	0.6	0.9	0.2	0.5	0.2	-0.7	0.2	-0.8	-0.5	-1.0	-1.1	1.5	0.3	0.8	1.8	0.9	0.7	0.8	0.7	0.2	0.1	-0.3	0.0
Cholesterol lowering medication	0.4	0.6	2.8	0.9	0.9	0.7	0.8	0.9	1.0	1.0	-0.2	0.9	1.7	0.4	0.5	0.9	-0.1	0.9	0.5	0.5	-0.3	0.6	0.3	0.7	0.9	0.9	0.9	0.8
Medication: Omeprazole (e.g. Zanprol)	0.4	0.5	3.8	0.5	0.6	0.9	0.0	0.5	0.2	0.4	1.2	0.4	1.9	1.1	0.6	0.3	-1.6	0.4	-0.3	-0.4	0.5	0.3	0.1	-0.4	0.6	0.0	-0.1	0.3
Basal cell carcinoma (self-reported)	0.4	0.4	1.7	0.4	0.7	1.3	0.7	0.3	0.4	0.5	-0.3	0.4	1.2	0.6	0.2	0.3	0.6	1.1	0.6	1.0	0.2	0.4	0.3	1.0	0.3	1.0	-0.1	0.3
Schizophrenia (2018)	0.3	0.7	3.7	0.4	0.4	1.9	-0.3	0.2	-0.1	0.4	1.2	0.5	0.5	1.2	1.9	0.4	-0.6	0.6	-0.6	-1.4	0.3	0.0	-0.2	-0.4	0.2	-1.2	-0.8	0.5
Heel T-Score	0.3	2.6	22.9	-0.0	-0.4	-4.8	1.5	-0.4	-0.3	0.1	-2.2	-0.1	-1.1	-1.6	0.4	-0.5	1.2	-1.5	1.8	1.9	1.2	1.4	1.1	-0.3	-0.1	3.2	2.0	0.4
Hearing difficulty/problems: Yes	0.3	0.4	4.0	-0.0	-0.2	0.4	0.1	0.2	0.2	-0.1	-2.0	-0.1	-0.2	-1.1	0.6	-0.4	1.1	-0.4	0.9	0.2	-0.8	0.3	0.3	0.3	-0.0	-0.0	1.1	-0.0
Diabetes (father)	0.3	0.4	2.1	-0.6	-0.5	0.2	-0.7	-0.5	-0.5	-0.6	-0.2	-0.5	0.2	0.1	-0.3	-0.3	-0.3	-0.1	-0.8	-0.6	-0.6	-1.5	-0.8	-1.0	-0.8	-0.7	-0.8	-0.7
Severe depression (siblings)	0.3	0.3	2.5	0.0	0.1	0.5	-0.4	0.1	0.1	-0.0	1.2	0.0	0.3	0.8	0.4	0.0	-0.3	0.3	-0.7	-0.6	0.5	-0.3	-0.2	-0.2	-0.2	-0.9	-1.6	-0.1
Townsend deprivation index at recruitment	0.3	0.5	3.6	0.7	0.8	1.9	0.5	0.7	0.9	0.9	0.5	0.8	0.4	0.1	0.8	0.8	-0.1	0.4	0.0	-0.4	0.7	0.3	0.5	-0.6	0.8	0.2	0.2	0.8
Average weekly fortified wine intake	0.3	0.4	2.2	0.3	0.1	-0.1	-0.4	0.4	0.2	0.2	1.5	0.4	-0.1	0.6	0.5	0.7	-1.2	-0.3	-0.7	-1.1	0.3	-0.9	-0.3	-0.8	0.1	0.1	-0.2	0.3
Taking other prescription medications	0.3	0.5	1.4	-0.8	-0.9	-0.5	-0.5	-0.6	-0.7	-0.9	-0.5	-0.7	1.1	-1.2	-0.9	-1.1	0.4	-1.0	-0.2	0.3	-0.8	-0.4	-0.6	0.3	-0.6	0.9	0.2	-0.8
Diverticular disease/diverticulitis (self-reported)	0.3	0.4	2.1	-0.4	-0.0	-0.5	0.2	-0.1	0.1	-0.3	-0.6	-0.2	-1.5	-1.1	0.1	-0.7	0.8	-0.4	0.1	1.4	-0.2	0.6	-0.3	0.2	-0.1	0.8	0.1	-0.6
Medication: Levothyroxine sodium	0.3	0.4	2.3	0.7	0.6	-0.1	0.2	0.8	0.7	0.7	0.9	0.6	1.5	0.9	0.2	1.3	-0.2	1.2	-0.3	-0.3	0.1	0.2	-0.1	0.4	0.5	-0.2	-0.4	0.5
Heel bone mineral density (BMD) T-score, automated (right)	0.3	0.8	5.1	0.3	-0.0	-1.5	1.0	-0.1	-0.3	0.3	-1.1	0.2	-0.2	-0.6	0.1	-0.2	0.9	-0.6	1.1	0.9	-0.1	0.1	0.6	1.5	-0.0	2.3	1.5	0.4
Qualifications: None of the above	0.3	0.6	3.1	-0.8	-0.6	-0.5	-0.9	-0.6	-0.7	-0.8	0.3	-0.9	0.5	0.1	-1.4	-0.1	0.2	0.3	-0.9	0.4	-0.7	-0.8	-1.3	0.4	-0.9	-0.3	-1.8	-1.1
Financial difficulties in last 2 years	0.3	0.3	1.8	0.0	-0.4	0.8	0.3	-0.1	-0.2	-0.2	-1.3	-0.2	-0.5	-0.5	-0.3	-0.7	0.8	-0.6	0.9	0.2	0.2	1.2	0.6	0.1	-0.1	0.3	0.9	0.2
Medication: Simvastatin	0.3	0.5	3.0	-0.7	-0.7	-0.2	-0.8	-0.6	-0.5	-0.6	0.0	-0.6	0.5	-0.4	-1.1	-0.7	0.1	-0.5	-1.0	-0.1	-1.7	-0.4	-1.2	0.6	-0.7	0.1	-0.4	-0.7
Arm fat percentage (right)	0.3	1.2	7.3	0.8	0.8	-0.5	1.5	0.8	0.9	1.0	-1.0	0.9	1.0	0.1	-1.7	0.1	-0.1	1.3	1.2	2.7	1.1	1.0	1.0	1.1	1.0	1.5	0.7	0.4
Time employed in main current job	0.3	0.3	0.8	-0.7	-0.8	-0.6	-0.8	-0.8	-0.9	-0.7	0.1	-0.7	-0.3	0.3	-0.2	-0.5	0.1	-0.7	-0.7	-0.3	-0.3	-0.1	-0.6	-0.1	-0.6	-0.2	-0.7	-0.7
Falls in the last year	0.3	0.4	2.5	-0.5	-0.6	-0.2	-0.3	-0.4	-0.5	-0.6	-0.6	-0.8	-1.6	-1.2	-0.6	-0.8	0.5	-0.9	0.1	0.2	-1.0	0.4	-0.2	0.3	-0.5	0.1	0.5	-0.6
Noisy workplace	0.3	0.4	1.6	-0.6	-0.5	-0.5	-1.0	-0.2	-0.2	-0.6	0.4	-0.7	-0.1	-0.5	-0.9	-0.0	-0.5	-0.2	-1.0	-0.0	-0.5	0.6	-1.0	-0.4	-0.3	-1.0	-1.3	-0.8
Serious illness, injury or assault of a close relative in last 2 years	0.3	0.3	1.8	0.8	0.6	0.4	0.7	0.4	0.3	0.7	0.1	0.8	0.0	0.3	1.3	0.8	0.3	0.2	0.6	-0.2	0.3	-0.3	0.9	-0.1	0.3	-0.1	0.7	0.8
Mouth/teeth dental problems: Dentures	0.3	0.6	2.9	0.7	0.3	0.7	0.9	0.4	0.4	0.6	-0.1	0.7	-0.1	0.4	1.2	0.3	1.4	0.3	0.9	0.9	0.4	0.9	1.0	1.7	0.3	0.8	0.5	0.7
Depression (self-reported)	0.3	0.4	1.6	-0.7	-0.6	-1.0	-0.7	-0.3	-0.4	-0.8	0.7	-0.8	0.4	0.2	-0.3	-0.3	0.1	-0.7	-0.5	0.2	0.1	-0.8	-0.2	-0.1	-0.5	-1.1	-1.3	-0.8
Lung cancer (father)	0.3	0.4	3.8	-0.1	0.2	-0.7	0.5	-0.1	-0.0	0.1	-0.7	0.1	0.0	0.0	-0.2	-0.3	1.0	0.6	0.4	1.2	-0.4	0.6	0.2	2.0	-0.1	0.3	-0.0	-0.2
Exposure to tobacco smoke at home	0.3	0.4	4.0	0.1	-0.2	-0.2	-0.2	0.3	0.3	0.1	0.2	0.2	1.1	0.6	-0.2	0.6	-0.7	0.1	-0.2	-0.8	1.2	-0.3	0.0	-2.0	0.1	-0.5	-0.8	0.2
Body fat percentage	0.3	1.3	8.9	-1.0	-0.8	-1.2	-0.1	-0.9	-0.8	-0.8	-1.2	-1.1	-0.4	-1.2	-3.0	-1.5	-0.4	-0.3	-0.0	2.2	-1.0	0.2	-0.6	1.2	-0.7	0.9	0.0	-1.4
Knee pain experienced in last month	0.3	0.5	2.2	0.1	-0.3	-0.7	0.5	0.1	0.0	0.0	-1.5	0.0	-0.5	-0.7	0.1	-0.1	1.1	-0.7	1.3	0.5	1.3	0.9	1.3	-0.6	0.1	-0.2	0.4	0.2
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.3	0.4	2.3	-0.3	-0.3	-0.6	-0.6	-0.4	-0.6	-0.4	0.3	-0.4	-0.3	0.4	-0.9	-0.2	-1.3	0.2	-0.8	-0.5	-0.9	-0.1	-0.6	0.0	-0.5	-1.5	-0.7	-0.4
Arm fat percentage (left)	0.3	1.0	7.5	0.5	0.6	-0.8	1.3	0.5	0.6	0.7	-1.1	0.5	0.7	-0.2	-1.9	-0.2	-0.3	0.9	1.0	2.7	0.8	0.9	0.8	1.0	0.7	1.6	0.7	0.1
Long-standing illness, disability or infirmity	0.3	0.4	2.5	-0.4	-0.6	-0.4	-0.1	-0.3	-0.5	-0.5	-0.9	-0.4	-0.3	-1.3	-1.0	-0.9	1.6	-1.0	0.2	0.5	0.1	0.6	-0.1	-0.2	-0.5	0.8	0.0	-0.4
Pain type(s) experienced in last month: Hip pain	0.3	0.4	1.6	-0.2	-0.2	0.1	0.3	-0.2	0.0	-0.1	-0.6	-0.2	-0.6	-0.4	0.4	-1.0	1.2	-1.0	0.4	0.9	0.4	1.3	0.5	0.4	0.2	0.9	0.6	0.0
Leg fat percentage (left)	0.3	1.0	8.3	-0.1	0.2	0.2	0.9	0.0	0.1	0.0	-1.8	-0.2	0.3	-1.0	-1.8	-0.7	0.8	0.3	1.0	2.9	-0.2	0.7	0.3	1.4	0.0	1.4	0.8	-0.5
Fractured/broken bones in last 5 years	0.3	0.5	1.9	0.6	0.4	-0.0	0.5	0.3	0.3	0.6	0.3	0.5	0.8	0.8	1.2	0.4	-1.4	0.2	0.3	-0.2	0.7	0.9	1.0	0.3	0.8	-1.0	0.6	0.7
Bipolar Disorder or Schizophrenia	0.2	0.6	1.4	-0.7	-0.5	0.8	-0.9	-0.7	-0.8	-0.6	0.7	-0.4	-1.2	0.1	0.6	-0.7	0.4	-0.5	-1.0	-1.0	-0.8	0.0	-0.9	-0.2	-0.8	-1.2	-1.1	-0.6
Intelligence (Savage-Jansen 2018)	0.2	0.6	2.0	0.5	0.6	0.4	0.6	0.9	1.0	0.4	-0.6	0.4	-0.7	-0.7	1.1	0.2	0.2	-0.2	0.6	0.6	1.3	1.2	0.7	-1.4	1.0	0.5	0.8	0.6
Ulcerative Colitis	0.2	0.3	1.2	-0.5	-0.5	-0.7	-0.0	-0.6	-0.3	-0.5	-1.1	-0.5	-0.7	-0.9	0.1	-0.6	0.7	-0.7	0.1	0.5	-0.6	0.0	-0.2	0.6	-0.6	0.7	0.2	-0.4
Blood Eosinophil Count	0.2	1.5	4.3	1.1	1.3	-0.3	1.8	1.0	1.0	1.1	-1.2	1.2	-0.2	0.3	1.2	0.6	1.5	1.0	1.4	1.8	0.9	1.5	1.4	2.1	0.9	1.8	1.0	1.0
Blood Platelet Count	0.2	2.6	26.2	1.4	1.6	5.1	0.8	1.5	1.4	1.3	0.1	1.3	1.1	1.4	-0.2	0.9	-1.2	2.2	0.7	-0.4	1.9	0.4	0.8	-2.2	1.7	-0.3	0.8	1.4
Hypothyroidism (self reported)	0.2	0.4	0.8	0.7	0.7	0.5	0.9	0.5	0.7	0.8	-0.4	0.7	0.0	0.4	0.9	0.6	0.0	0.9	0.5	0.5	0.4	0.8	0.6	0.8	0.5	0.4	0.5	0.7
Lung FEV1/FVC ratio	0.2	1.0	3.8	-0.7	-0.7	1.3	0.1	-1.2	-1.4	-0.8	-1.9	-0.8	-0.2	-0.7	-1.2	-1.9	1.2	-0.2	0.6	0.6	-0.6	-0.4	0.3	1.0	-1.3	-1.1	0.3	-0.5
Number of treatments/medications taken	0.2	0.4	2.8	0.1	-0.3	0.2	-0.4	-0.1	-0.1	0.0	1.1	0.2	1.7	0.3	0.2	-0.1	-0.4	-0.3	-0.9	-1.0	0.6	-0.9	-0.3	-1.1	-0.2	-0.5	-0.8	0.1
Average weekly spirits intake	0.2	0.2	0.8	0.4	0.5	-0.4	0.4	0.4	0.5	0.4	0.9	0.3	0.7	0.6	-0.1	0.6	-0.4	0.4	0.1	0.5	0.5	0.6	0.3	0.9	0.6	0.4	-0.1	0.2
Sensitivity / hurt feelings	0.2	0.4	1.5	-0.4	-0.5	0.0	-1.0	-0.3	-0.3	-0.5	1.0	-0.5	-0.0	0.5	0.4	0.5	-1.2	-0.1	-1.0	-0.8	-0.9	-0.7	-1.0	-0.2	-0.3	-0.3	-0.8	-0.7
Medication: Metformin	0.2	0.3	1.5	-0.3	-0.3	-0.7	0.4	-0.3	-0.1	-0.2	-0.8	-0.0	-0.3	-0.8	-0.4	-0.5	1.2	-0.6	0.5	0.8	-0.0	-0.1	0.2	1.1	-0.3	1.2	0.5	0.0
Relative age voice broke	0.2	0.3	1.3	-0.4	-0.4	1.1	-0.4	-0.6	-0.6	-0.4	-0.1	-0.4	-0.6	-0.2	0.3	-0.3	0.5	-0.2	-0.1	-0.4	0.0	-0.6	-0.0	-1.0	-0.7	-0.9	-0.7	-0.4
Age when periods started (menarche)	0.2	0.5	4.3	0.5	0.8	2.1	0.2	0.7	0.6	0.5	0.4	0.4	-1.2	-0.4	0.4	0.5	0.3	0.4	0.2	0.2	0.8	0.5	0.5	-0.4	0.6	-0.7	-0.2	0.4
Heel bone mineral density (BMD) T-score, automated (left)	0.2	0.5	3.6	0.1	-0.2	-1.7	0.6	-0.4	-0.5	0.1	-0.4	0.1	0.2	0.1	-0.1	-0.3	0.3	-0.4	0.5	0.3	-0.6	-0.7	0.0	1.6	-0.3	1.9	1.1	0.2
Supplements: Glucosamine	0.2	0.2	2.2	-0.0	-0.2	-1.3	-0.3	-0.0	-0.2	-0.1	-0.1	-0.0	0.4	0.3	-0.1	0.1	-0.3	-0.3	0.1	-0.8	-0.1	-0.0	0.3	0.0	0.0	-1.5	-0.1	0.0
Chronic bronchitis/emphysema (father)	0.2	0.2	2.3	0.0	0.2	-0.5	0.1	0.0	0.1	0.3	0.4	0.2	1.5	0.3	-0.0	0.5	0.3	0.5	-0.4	0.5	-0.1	-0.3	-0.2	0.4	0.1	-0.2	-0.6	-0.0
Past tobacco smoking	0.2	0.4	1.1	0.7	0.2	0.5	0.7	0.0	0.2	0.8	-0.1	1.0	-0.1	0.9	-0.0	0.1	-0.4	1.0	0.3	-0.6	0.9	0.6	0.8	-0.3	0.3	-0.6	0.6	1.0
Allergy	0.2	0.4	2.1	-0.4	-0.8	-1.0	-0.2	-0.6	-0.8	-0.5	-0.2	-0.7	-0.9	0.3	-1.0	-0.3	-0.2	-0.2	0.0	-0.1	-0.9	0.5	-0.3	1.4	-0.5	-0.1	0.1	-0.4
Alcohol intake versus 10 years previously	0.2	0.3	0.9	0.6	0.4	-0.5	0.8	0.3	0.2	0.7	0.3	0.7	-0.0	0.9	0.2	0.0	0.0	0.5	0.4	-0.3	0.8	0.5	0.7	0.4	0.4	0.3	0.4	0.9
Frequency of tiredness / lethargy in last 2 weeks	0.2	0.3	1.6	0.4	0.2	1.2	0.1	0.5	0.4	0.2	0.1	0.2	0.5	0.3	1.3	0.4	-0.5	0.1	0.4	-0.1	0.6	1.0	0.7	-0.5	0.6	-0.5	0.2	0.4
Prospective memory result	0.2	0.2	1.8	0.1	0.5	-0.4	-0.2	0.6	0.5	0.0	-0.1	0.1	1.3	-0.1	-0.1	0.7	-0.6	0.6	-0.2	0.6	-0.0	0.1	-0.3	-0.7	0.3	-0.4	-0.6	-0.3
Loud music exposure frequency	0.2	0.3	0.8	-0.4	-0.6	-0.3	-0.4	-0.5	-0.5	-0.6	0.1	-0.6	-0.4	-0.1	0.9	-0.6	-0.0	-0.8	-0.2	-0.8	-0.8	0.0	-0.3	0.7	-0.5	0.4	0.5	-0.3
Headache pain in last month	0.2	0.4	1.8	0.4	0.5	1.4	0.7	0.3	0.6	0.5	-0.3	0.6	-0.3	0.3	0.5	0.1	0.5	-0.1	0.7	0.3	0.5	1.2	0.8	0.4	0.8	1.1	0.9	0.6
Medication for cholesterol, blood pressure or diabetes	0.2	0.4	1.0	0.4	0.9	0.4	0.8	0.5	0.6	0.6	-0.7	0.3	-0.7	-0.1	1.0	0.4	0.2	0.4	0.8	0.8	0.2	0.8	0.7	0.4	0.8	0.3	0.9	0.4
Exposure to tobacco smoke outside home	0.2	0.2	1.7	-0.1	-0.1	-0.2	-0.3	0.2	0.3	-0.2	0.7	-0.1	1.3	0.7	-0.7	0.0	-0.2	0.3	-0.4	-0.1	-0.1	-0.3	-0.8	-0.2	0.1	0.8	-0.6	-0.2
Reason for reducing amount of alcohol drunk: Health precaution	0.2	0.3	1.8	0.3	0.0	0.2	0.1	0.3	0.1	0.2	-0.6	0.1	-0.7	-0.3	0.6	0.1	-0.3	0.1	0.3	-0.5	-0.5	1.3	0.4	0.9	0.4	-1.0	0.6	0.3
Qualifications: College or University degree	0.2	0.7	4.0	0.3	0.0	0.6	-0.2	0.0	0.1	0.3	0.8	0.5	-0.4	0.6	1.8	0.5	-0.5	-0.1	-0.3	-1.9	0.5	-1.2	0.6	-1.4	-0.0	-2.0	-0.2	0.8
Medication: Omeprazole	0.2	0.2	2.7	0.1	0.1	0.3	-0.0	-0.0	-0.2	-0.0	0.3	-0.1	1.6	0.2	0.3	-0.2	-0.8	-0.4	-0.0	-0.2	0.3	0.7	0.2	-0.5	0.1	0.2	0.3	0.1
Handedness (chirality/laterality): Left-handed	0.2	0.2	0.9	0.5	0.4	0.4	0.0	0.9	0.9	0.3	0.8	0.3	0.5	0.1	-0.2	0.9	0.1	0.3	0.1	-0.6	0.3	0.1	0.3	-0.2	0.5	-0.4	-0.2	0.5
Back pain experienced in last month	0.2	0.3	1.1	-0.5	-0.5	-0.4	-0.3	-0.6	-0.7	-0.6	-0.6	-0.6	-0.6	-0.5	-0.3	-0.9	0.6	-1.0	0.0	0.2	-0.8	-0.1	-0.2	0.5	-0.5	0.3	0.6	-0.5
Medication: Blood pressure	0.2	0.4	1.5	-0.6	-0.8	-1.2	-0.5	-0.9	-0.7	-0.3	0.2	-0.4	1.0	0.1	-0.7	-0.3	-0.3	-0.3	-0.9	-0.5	-0.6	-0.9	-0.8	-0.9	-0.7	-0.6	-0.5	-0.5
High cholesterol (Self-reported)	0.2	0.4	4.1	0.1	0.3	0.2	-0.3	0.0	0.0	0.2	0.7	0.2	2.0	0.5	-0.3	0.4	-0.8	0.8	-0.8	-0.3	-0.3	-0.5	-0.4	0.1	-0.1	-1.2	-0.9	-0.1
Medication: Bendroflumethiazide	0.2	0.3	1.3	-0.4	-0.4	-0.8	-0.6	-0.4	-0.3	-0.2	-0.2	-0.1	-0.6	-0.6	-0.5	-0.1	0.7	-0.5	-0.7	-0.1	-1.0	-1.2	-0.7	-0.3	-0.5	-0.4	-0.2	-0.6
Medication: Atorvastatin	0.2	0.3	1.3	-0.5	-0.6	0.1	-0.1	-0.7	-0.8	-0.5	-0.3	-0.3	0.6	-0.2	-0.5	-0.5	1.0	-0.3	0.1	0.0	-0.6	-1.1	-0.0	0.7	-0.8	-0.2	-0.2	-0.4
Ulcerative Colitis (UC)	0.1	0.2	1.3	-0.2	-0.1	-0.2	0.2	-0.2	-0.2	-0.1	-1.0	-0.1	-1.1	-0.8	0.4	0.0	0.2	-0.2	0.3	0.4	-0.2	0.1	0.0	0.4	-0.2	0.2	0.3	-0.0
Bipolar Disorder (2011)	0.1	0.1	1.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	-0.4	-0.1	-0.8	0.0	-0.6	0.2	-0.9	0.4	-0.4	-1.0
Body Mass Index (BMI) (2010)	0.1	0.2	1.6	0.3	-0.1	-0.1	0.5	-0.1	-0.2	0.2	0.1	0.2	0.8	0.4	-0.1	-0.0	0.2	0.1	0.4	0.3	0.6	0.2	0.4	0.0	0.0	1.3	-0.1	0.3
HbA1C	0.1	0.2	0.9	0.2	0.1	0.3	0.3	-0.1	-0.0	0.1	-0.6	0.2	-0.3	-0.1	0.9	0.1	0.5	0.4	0.4	0.1	0.8	0.2	0.7	-0.2	-0.0	-0.8	-0.3	0.3
LDL Cholesterol	0.1	0.1	0.7	-0.2	0.0	-0.1	0.1	0.2	0.3	-0.1	-0.7	-0.2	0.6	-0.8	-0.4	-0.1	-0.1	-0.3	0.3	0.1	-0.3	0.4	0.4	-0.2	0.3	-0.8	0.5	-0.1
Lupus	0.1	0.2	1.1	0.0	-0.3	0.5	0.2	-0.4	-0.7	-0.1	0.2	-0.1	0.0	1.0	0.5	-0.5	0.3	-0.3	0.3	-0.6	0.7	0.1	0.3	0.4	-0.2	0.4	0.2	0.3
Blood Red Count	0.1	0.6	7.2	0.0	-0.1	-0.1	0.2	-0.3	-0.7	-0.0	0.1	-0.4	-0.6	0.5	-0.3	-0.3	-1.9	0.0	0.1	0.2	-0.4	-0.5	-0.5	-0.9	0.1	2.7	1.2	-0.1
Other serious medical condition/disability diagnosed by doctor	0.1	0.2	0.8	-0.1	-0.3	-0.3	-0.1	0.2	-0.1	-0.3	-0.5	-0.2	0.6	-0.6	-0.1	-0.4	-0.1	-0.7	0.1	0.1	0.7	0.9	0.1	-0.8	0.1	0.6	0.3	-0.1
Maternal smoking around birth	0.1	0.2	1.7	0.2	0.6	0.2	0.3	0.3	0.4	0.2	-0.0	0.1	1.3	-0.1	0.5	0.3	-0.5	-0.2	0.3	0.6	0.2	-0.4	0.1	0.4	0.4	1.1	0.4	0.0
Hypothyroidism/myxoedema (self-reported)	0.1	0.1	1.4	0.0	0.0	-0.2	0.2	-0.0	0.1	0.1	0.0	0.0	-0.3	-0.1	-0.0	0.0	0.3	0.3	-0.1	0.3	-0.6	0.4	-0.1	1.2	-0.1	0.3	0.3	0.0
Shortness of breath walking on level ground	0.1	0.2	0.8	0.2	0.2	-0.0	0.4	-0.1	0.1	0.3	0.2	0.4	0.4	0.1	0.8	-0.2	-0.1	0.5	-0.2	0.6	0.8	0.9	0.3	0.2	0.0	-0.4	-0.3	0.1
Medication: Blood pressure	0.1	0.2	0.9	-0.0	-0.5	-0.3	-0.4	-0.1	-0.2	-0.2	0.7	0.0	0.3	0.4	-0.7	-0.3	0.0	-0.3	-0.4	-0.6	-0.0	-0.6	-0.5	-0.1	-0.3	1.0	-0.3	-0.0
Overall health rating	0.1	0.2	1.6	0.2	0.1	0.3	0.4	0.4	0.2	0.1	0.0	0.1	1.2	0.2	-0.4	-0.4	0.2	0.3	0.3	1.0	0.5	0.9	0.2	0.3	0.4	0.9	-0.1	-0.1
Loneliness, isolation	0.1	0.1	0.5	-0.1	-0.3	-0.1	-0.3	-0.3	-0.1	-0.1	0.6	-0.0	-0.0	0.7	0.2	-0.0	-0.7	-0.1	-0.5	-0.6	-0.2	0.3	-0.2	-0.1	0.1	-0.2	0.0	0.0
Ever taken oral contraceptive pill	0.1	0.1	1.1	0.1	-0.1	-0.2	-0.2	-0.3	-0.4	0.1	0.4	0.2	-0.2	0.6	-0.2	-0.2	0.6	-0.2	-0.3	-1.0	-0.2	-0.7	-0.1	-0.2	-0.3	0.4	-0.0	0.3
Alcohol drinker status: Never	0.1	0.1	0.6	-0.0	0.1	0.6	0.2	-0.0	-0.1	-0.0	-0.0	-0.0	-0.1	-0.2	-0.4	0.3	0.3	0.0	0.1	0.8	0.7	0.0	0.2	0.1	0.0	0.2	-0.1	-0.3
Hair Pigment	0.0	1.1	3.0	0.3	0.6	-0.4	0.5	-0.0	1.4	1.2	1.7	1.2	0.7	1.2	1.3	0.8	-1.6	0.9	-0.7	-0.8	-0.5	1.7	-0.2	1.4	1.1	0.8	1.1	1.4
Tanning	0.0	0.5	2.2	-0.6	-0.6	-0.7	-0.6	-0.3	-0.6	-0.8	-0.5	-0.9	1.0	-0.3	-1.2	-0.5	1.1	0.2	-0.3	-0.2	-0.3	-0.8	-0.7	-0.3	-0.9	-0.9	-1.5	-0.8

Hub : Genes

SMYD4

Models

Trait associations