Hub : Genes

SERPINF1

Models

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.3410	0.0400	0.0e+00	0.301	0.287	0.344	0.327	0.335	3.7e-37	4.3e-35	2.2e-43	8.4e-41	4.9e-42
2	GTEx	Adipose Subcutaneous	0.1870	0.0550	2.0e-04	0.050	NA	0.020	NA	0.022	6.2e-05	NA	8.3e-03	NA	6.2e-03
3	GTEx	Artery Tibial	0.1093	0.0481	9.2e-03	0.004	NA	0.000	NA	0.003	1.4e-01	NA	3.3e-01	NA	1.9e-01
4	GTEx	Cells Transformed fibroblasts	0.1990	0.0430	1.2e-06	0.107	NA	0.126	NA	0.159	2.0e-08	NA	1.0e-09	NA	5.6e-12
5	GTEx	Muscle Skeletal	0.1030	0.0376	2.2e-03	0.045	NA	0.032	NA	0.032	3.1e-05	NA	3.9e-04	NA	3.9e-04
6	GTEx	Pancreas	0.3080	0.0850	3.2e-04	0.081	NA	0.065	NA	0.041	2.6e-04	NA	1.1e-03	NA	8.0e-03
7	GTEx	Testis	0.2920	0.0890	1.4e-03	0.138	NA	0.091	NA	0.127	1.1e-06	NA	7.3e-05	NA	3.0e-06
8	GTEx	Thyroid	0.1270	0.0450	3.2e-03	0.005	NA	0.004	NA	0.017	1.1e-01	NA	1.5e-01	NA	1.8e-02
9	METSIM	Adipose	0.0572	0.0196	7.1e-04	0.002	0.021	0.009	0.022	0.001	1.7e-01	3.3e-04	1.6e-02	2.5e-04	2.4e-01
10	NTR	Blood	0.0233	0.0100	6.2e-03	0.012	0.012	0.016	0.014	0.014	8.9e-05	8.1e-05	5.2e-06	1.8e-05	2.2e-05
11	ROSMAP	Brain Pre-frontal Cortex	0.0444	0.0261	4.2e-02	0.016	0.003	0.015	0.014	0.016	3.0e-03	1.4e-01	3.9e-03	6.0e-03	3.6e-03
12	TCGA	Breast Invasive Carcinoma	0.0627	0.0225	1.7e-07	0.022	0.031	0.018	NA	0.017	2.3e-05	5.1e-07	1.1e-04	NA	1.4e-04
13	TCGA	Colon Adenocarcinoma	0.1490	0.0600	1.9e-03	0.059	0.005	0.043	NA	0.045	2.6e-04	1.5e-01	1.7e-03	NA	1.2e-03
14	TCGA	Brain Lower Grade Glioma	0.0684	0.0367	9.3e-04	-0.001	0.023	0.017	NA	0.000	4.3e-01	1.0e-03	4.8e-03	NA	3.1e-01
15	TCGA	Lung Adenocarcinoma	0.0807	0.0317	1.3e-04	0.003	0.022	0.026	NA	0.020	1.4e-01	1.0e-03	4.2e-04	NA	2.0e-03
16	TCGA	Prostate Adenocarcinoma	0.0606	0.0247	3.1e-05	0.026	0.048	0.047	NA	0.035	9.5e-04	8.8e-06	1.1e-05	NA	1.2e-04

Trait associations

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16
Bipolar Disorder (2018)	0.8	1.3	4.5	-1.2	-1.2	0.3	-1.3	-0.1	1.7	-1.1	-0.8	-2.1	1.6	0.0	-0.3	0.8	-0.6	0.1	-1.6
Bipolar Disorder or Schizophrenia	0.8	2.0	18.1	-0.9	-0.1	-0.6	-0.0	0.2	4.3	0.3	0.6	-3.3	1.2	0.0	0.0	-0.2	-0.3	0.2	-0.2
Depressed Affect (Nagel 2018)	1.1	2.3	9.1	0.3	0.6	-1.6	2.3	-1.7	-0.2	3.0	1.4	2.1	0.2	0.1	0.1	-2.0	1.6	-0.8	1.6
Depression (Nagel 2018)	1.0	1.5	5.1	-0.8	-0.7	-0.7	1.2	-1.7	-1.5	2.2	0.4	1.7	1.2	0.4	-1.2	-1.3	1.3	-1.3	0.7
Intelligence (Savage-Jansen 2018)	0.2	0.7	2.6	0.8	1.0	-0.1	1.0	-1.5	1.6	0.0	0.1	0.2	-0.1	1.6	-0.9	-0.1	0.1	-0.0	0.6
Neuroticism (Nagel 2018)	1.2	2.7	12.2	-0.1	0.6	-0.6	2.5	-1.6	0.3	3.5	1.3	1.8	0.9	-0.1	0.1	-0.8	2.7	0.9	2.6
Schizophrenia (2018)	1.0	2.1	16.6	-0.1	0.8	-1.0	1.0	0.3	4.1	1.3	1.5	-2.7	0.3	0.0	0.3	-0.9	0.1	0.2	1.1
Schizophrenia vs Biploar Disorder	0.3	0.4	2.2	0.1	0.2	-0.1	0.4	0.3	0.6	1.0	0.3	-0.3	-0.0	0.0	0.3	0.2	0.8	1.3	1.5
Worry (Nagel 2018)	1.2	2.5	12.6	-0.2	0.6	0.1	2.4	-0.8	0.9	3.5	1.6	1.0	0.9	-0.3	0.9	-0.0	2.6	1.3	2.6
Alzheimer’s Disease (in mother)	0.4	0.5	1.7	-0.5	-0.3	0.7	-0.0	-0.0	0.9	0.4	1.3	-1.0	-0.2	0.0	1.1	0.4	0.8	1.1	0.1
Alzheimer’s Disease (in father)	0.5	0.6	3.3	0.6	0.2	0.3	0.7	-0.7	-1.0	0.2	0.8	1.8	-0.6	-0.4	0.9	-0.3	0.9	0.2	0.2
Alzheimer’s Disease (including proxy)	1.7	2.5	8.6	1.0	1.1	1.5	1.5	-0.1	0.0	1.1	2.7	0.4	-1.3	0.5	2.9	0.9	2.7	2.0	1.2
Crohns Disease (2017)	1.3	2.9	10.4	-1.9	-0.9	-0.7	-0.7	-2.4	-3.2	0.2	0.3	-2.1	1.6	0.6	-2.1	-1.2	1.0	-2.4	-2.0
Irritable Bowel Disease (IBD)	0.7	1.8	10.8	-1.5	-0.5	0.1	-0.6	-1.6	-3.3	-0.0	0.1	-2.1	1.1	-0.5	-1.6	-0.3	0.4	-1.2	-1.5
Ulcerative Colitis (UC)	0.1	0.3	1.6	-0.1	0.3	0.2	-0.2	-0.1	-1.2	-0.2	0.5	-1.0	-0.3	-0.9	-0.4	0.1	-0.4	0.4	-0.2
Major Depression (MDD)	0.8	1.0	4.7	1.5	1.7	0.5	1.6	1.5	0.0	2.2	0.6	0.1	0.0	0.0	0.0	0.9	0.0	0.0	0.0
Reaction Time	0.8	1.5	5.2	-0.9	-0.5	1.0	-0.4	2.2	1.6	0.6	-2.3	0.0	0.1	0.6	0.8	1.3	1.4	2.2	0.3
Verbal and Numeric Reasoning (VNR)	0.2	0.6	1.4	1.2	0.9	-0.4	0.7	-0.3	0.8	-0.7	-1.2	1.0	-0.2	1.1	-0.6	-0.5	-0.2	0.5	0.5
Breast Cancer	0.8	2.0	9.4	-0.4	0.5	-1.9	-0.9	3.1	-0.1	-1.7	0.2	-2.6	-0.2	-1.2	-1.7	-1.6	-1.1	0.1	-0.2
Ovarian Cancer	1.1	1.5	7.3	0.8	1.0	1.0	1.5	0.4	-0.2	1.3	-0.4	-0.6	-1.2	0.7	2.0	1.1	2.7	1.2	0.9
Prostate Cancer	0.9	1.3	6.1	-1.9	-1.4	-0.6	-1.5	0.0	0.4	-0.7	0.1	-0.7	1.1	-0.9	-2.5	-0.8	-1.7	0.0	-0.3
Age at First Birth	1.1	1.5	6.1	-1.8	-1.4	-1.5	-1.5	-0.1	0.5	-0.4	-0.4	-2.5	1.1	-0.8	-1.8	-1.4	-0.1	-0.4	-0.9
Bipolar Disorder (2011)	0.1	0.1	1.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	-0.2	0.1	-0.7	0.1	-1.0
Body Mass Index (BMI) (2010)	0.6	0.8	4.5	-0.1	-0.7	-0.1	-0.7	-0.1	-1.4	-0.1	0.7	1.6	-0.1	-0.6	-0.6	-0.7	-2.1	-0.9	0.1
Coronary Artery Disease (CAD)	0.8	1.0	4.1	-1.0	-0.6	0.5	-0.1	-1.1	-1.9	-0.4	0.9	2.0	1.1	0.0	-1.5	0.0	-0.4	-0.7	-0.4
Crohns Disease (2012)	1.0	1.6	4.1	-1.9	-1.3	-1.2	-1.6	0.3	-0.8	-0.7	-0.9	-1.6	1.1	0.0	-1.0	-1.9	-0.6	-1.2	-2.0
Mean Putamen Volume	1.1	1.2	4.3	0.9	1.5	0.0	2.1	-1.4	-1.6	1.5	0.6	0.8	-0.5	1.0	0.0	-0.4	0.7	-1.7	0.5
Fasting Glucose	1.8	2.2	11.8	-2.4	-1.6	-0.6	-1.7	0.0	1.7	-0.5	0.9	-3.4	1.3	-1.1	-1.4	-0.9	-0.6	0.2	-1.2
HbA1C	0.5	0.6	2.4	-0.5	-0.7	-0.6	-0.3	-1.5	0.4	-0.4	1.1	-0.5	0.7	0.2	-1.0	-0.3	-0.6	-1.2	-0.6
HDL Cholesterol	0.8	1.3	5.1	-0.3	0.6	-1.4	1.3	-1.0	1.6	1.8	1.1	-2.3	0.7	0.0	-0.2	-0.9	1.1	-0.6	0.5
LDL Cholesterol	0.4	0.6	5.0	-0.0	0.7	0.5	0.5	-2.2	0.1	-0.1	-0.6	0.2	0.2	0.0	-0.4	-0.1	1.7	0.2	-0.5
Lupus	0.9	1.4	4.3	-0.5	-0.7	-2.1	-0.6	0.1	-0.5	-0.4	-2.0	0.5	0.2	-1.6	-0.7	-1.8	-1.7	-1.6	-0.5
Neuroticism (2016)	0.7	1.0	4.7	-0.3	0.2	-0.3	0.9	0.7	0.6	2.2	-1.0	0.6	0.7	-0.2	-0.3	-0.6	1.9	0.8	1.5
Primary Biliary Cirrhosis	1.5	2.2	5.8	-1.2	-1.8	1.6	-2.4	0.0	-0.7	-2.1	-1.8	-0.8	1.5	-1.3	-0.1	1.3	-1.7	-0.1	-2.3
Rheumatoid Arthritis	0.5	0.7	4.0	0.5	0.5	0.7	-0.6	0.1	-0.3	-2.0	-1.0	0.3	-0.6	1.2	0.9	0.8	-1.0	0.5	-0.9
Schizophrenia (2014)	1.3	2.8	22.0	-1.2	-0.3	-1.5	0.2	-1.1	4.7	0.9	0.9	-3.5	1.6	0.0	-0.6	-1.2	0.6	0.6	0.2
Triglycerides	0.8	1.3	4.8	-0.8	-0.9	2.0	-0.8	-1.5	-0.8	-1.0	-0.2	0.2	1.4	0.0	0.3	1.5	0.6	-0.8	-2.2
Type 2 Diabetes (T2D) (2012)	0.7	0.8	2.5	-1.1	-1.1	-1.0	-1.1	0.4	0.3	-0.6	0.2	0.5	0.7	0.0	-0.8	-0.7	-1.6	-1.3	-1.0
Ulcerative Colitis	0.2	0.3	1.3	-0.4	-0.2	0.2	-0.7	0.4	0.4	-0.7	-0.7	-0.7	-0.1	0.0	-0.3	-0.2	-0.9	1.2	-0.3
Blood Eosinophil Count	0.2	1.4	7.7	1.1	0.6	0.7	0.1	1.2	-0.7	-0.7	-1.3	2.8	-1.5	-0.0	1.7	1.0	-0.4	1.5	0.4
Blood Platelet Count	0.4	4.1	26.2	1.7	2.9	-2.5	1.4	0.3	5.1	1.1	-0.1	-3.4	-0.4	0.7	-1.0	-0.5	0.5	-2.1	1.4
Blood Red Count	0.3	2.5	9.0	0.2	-0.9	-0.0	-1.1	3.0	-1.1	-0.5	-1.4	2.9	-0.8	-2.1	-1.1	-0.3	-1.9	1.5	2.2
Blood White Count	0.7	5.1	16.2	3.9	4.0	0.4	1.7	2.2	-0.8	-0.1	-1.6	2.4	-3.4	1.9	2.1	2.0	0.9	1.7	2.5
Heel T-Score	1.6	13.1	90.8	0.0	-1.2	0.2	-1.4	2.1	-9.5	-1.9	-0.4	7.6	-2.2	-0.2	-2.1	-1.0	-5.1	-3.4	-1.1
BMI	1.2	7.2	37.9	2.3	0.4	3.9	-0.5	-1.0	-5.0	-2.4	-1.5	6.2	-2.2	-0.0	1.1	3.6	-1.7	0.2	0.4
Height	1.9	37.3	92.9	-9.4	-8.6	0.4	-9.6	1.4	7.9	-5.8	-2.7	-8.7	6.4	-4.6	-3.8	-0.1	-2.8	6.5	-5.7
Waist Hip Ratio (WHR)	0.6	2.7	8.2	-2.3	-2.8	-0.9	-2.9	1.7	0.9	-0.9	-2.2	1.1	1.3	0.3	0.2	-1.4	0.6	1.9	-1.4
Systolic Blood Pressure	0.6	2.9	10.1	-1.3	-1.3	1.0	-1.3	-0.3	0.8	-1.4	-3.2	2.3	2.9	-2.4	-1.1	1.9	-1.1	1.5	-0.1
Smoking Status	0.8	1.9	8.8	1.4	1.2	1.1	-0.0	3.0	-1.4	-0.7	0.2	-0.8	-2.3	2.4	1.3	1.1	0.2	0.5	0.0
Allergy or Eczema	0.6	1.5	4.9	1.6	2.2	0.5	1.7	0.7	0.5	1.2	1.1	-1.9	-1.2	-0.3	0.3	0.7	-0.1	0.4	1.8
Cardiovascular Disease	0.9	2.9	11.4	-1.6	-2.3	1.7	-1.8	0.5	-1.7	-0.8	-3.4	1.8	2.2	-1.7	-0.3	1.9	-1.0	1.1	-0.7
Hypothyroidism (self reported)	0.1	0.2	0.8	0.4	-0.4	-0.3	0.2	-0.4	0.1	0.0	-0.9	-0.4	-0.6	0.8	0.2	0.2	0.2	-0.2	0.2
Respiratory disease	0.2	0.4	1.3	-1.1	-0.9	1.0	0.1	0.4	0.2	0.3	-0.5	0.8	0.7	0.8	0.0	0.7	0.3	0.6	-0.4
Type 2 Diabetes (T2D) (2018)	0.6	1.1	3.3	1.2	0.9	1.3	-0.0	1.3	0.2	-0.7	-0.1	1.8	-1.3	0.2	1.2	1.2	-0.7	1.5	0.6
Lung FEV1/FVC ratio	1.0	5.2	24.2	-1.6	-1.6	-2.2	-2.4	-2.4	0.3	-2.1	-0.0	-4.9	1.9	-1.5	-2.7	-1.4	-1.3	-2.9	-2.8
Lung FVC	1.1	5.7	14.7	-2.7	-3.8	-1.3	-2.9	-1.9	-0.6	-2.4	-3.0	0.3	2.3	-1.8	-2.7	-0.8	-3.3	-2.3	-2.7
Neuroticism	1.1	2.6	15.1	0.2	0.7	-0.8	2.5	-1.3	0.3	3.9	1.4	1.6	0.6	-0.5	0.4	-0.9	2.0	-0.1	2.7
Chronotype (morning person)	0.7	1.6	4.1	1.6	2.0	-0.4	2.0	1.1	-1.2	0.7	0.4	1.0	-1.9	1.7	1.0	-0.2	0.6	0.2	1.4
Hair Pigment	0.1	3.4	8.4	1.0	2.0	-0.8	1.6	2.6	2.5	2.2	2.2	0.8	-2.9	1.7	1.7	-1.2	1.7	1.2	1.9
Tanning	0.1	1.7	10.8	-0.4	0.0	-0.4	-0.2	-0.1	-2.4	-0.9	-0.7	-0.4	0.4	-0.1	-0.3	-0.4	-2.4	-3.3	-1.7
Hand grip strength (left)	0.6	1.5	5.1	-1.4	-1.7	-0.0	-1.9	-0.5	0.6	-2.1	0.2	-0.4	1.1	-1.4	-1.0	0.1	-2.3	-0.1	-1.3
Number of treatments/medications taken	0.2	0.3	0.8	-0.5	-0.5	-0.5	0.4	-0.9	0.7	0.9	0.0	0.5	0.9	-0.7	-0.3	-0.5	0.0	0.1	0.6
Average weekly spirits intake	0.4	0.6	4.2	0.4	-0.2	0.8	-0.0	0.0	-2.1	-0.4	0.9	0.4	-0.7	0.5	0.9	0.6	0.8	0.2	0.1
Sensitivity / hurt feelings	0.7	1.1	6.2	-0.2	-0.1	0.1	0.5	0.9	2.5	0.3	-0.8	-0.1	0.6	0.9	0.6	0.4	1.4	2.4	1.0
Frequency of depressed mood in last 2 weeks	0.5	0.6	1.8	-0.2	-0.0	-0.1	1.0	-1.1	-1.0	1.2	-0.5	0.7	0.9	0.8	-0.7	-0.2	1.3	-0.7	0.5
Hearing difficulty/problems: Yes	0.4	0.5	2.9	0.2	0.4	0.4	0.1	-0.1	0.8	-0.5	-0.1	-0.3	0.6	1.3	0.4	0.0	1.5	1.7	-0.2
Relative age of first facial hair	1.0	2.0	7.8	-1.7	-1.1	-1.0	-1.3	-0.4	-0.0	-1.1	-2.2	-2.8	1.5	-0.6	-1.6	-0.3	-1.2	-1.2	-1.6
Other serious medical condition/disability diagnosed by doctor	0.3	0.4	3.2	-0.1	0.2	-0.4	0.2	-0.6	-0.9	0.1	-1.1	1.8	0.2	-0.3	-0.6	-0.4	-0.0	0.1	0.1
Ever used hormone-replacement therapy (HRT)	1.8	2.3	8.6	-2.7	-2.0	0.6	-0.7	-2.1	0.4	0.7	0.7	-1.9	2.9	-1.3	-1.5	0.1	1.3	0.4	-0.8
Ever had hysterectomy (womb removed)	0.5	0.5	2.1	-0.7	-0.6	1.5	0.2	-0.6	-1.0	0.1	0.2	-0.8	0.9	-1.2	-0.2	1.1	-0.2	0.3	-0.1
Systolic blood pressure, automated reading	0.8	2.4	13.2	-0.6	-0.5	1.4	-0.4	-0.8	-1.1	-1.2	-2.0	3.6	2.0	-2.3	-0.6	1.8	-0.4	1.5	0.2
Eye problems/disorders: Diabetes related eye disease	1.5	1.6	5.2	1.3	1.2	1.7	0.3	1.5	-1.2	-0.5	0.5	0.7	-2.3	-0.3	1.6	1.7	0.1	1.8	1.1
Angina	0.7	0.9	7.5	-0.2	-0.4	1.0	-0.7	1.0	-0.4	-0.7	-0.6	2.7	0.3	-0.5	0.5	1.2	-0.5	0.8	-0.3
Medication for hormone replacement therapy	0.9	1.0	3.5	-1.1	-1.5	-0.1	-1.3	-0.6	0.7	-1.1	-1.8	-0.3	1.1	-1.9	-0.7	-0.0	0.2	0.4	-0.9
Vitamin and mineral supplements	0.9	1.3	4.8	0.8	-0.1	0.2	-1.2	1.7	-1.2	-2.1	-0.4	1.0	-1.1	0.2	0.2	0.1	-2.2	1.3	-0.1
Supplements: Zinc	1.3	1.5	7.5	0.2	0.4	-0.2	1.4	-1.8	-0.4	1.9	2.7	-1.3	-0.1	-0.4	0.4	0.1	1.9	-0.4	1.1
Medication: Co-codamol	2.3	2.6	10.7	1.7	1.1	1.8	0.5	3.3	1.3	-0.1	-0.4	0.2	-2.2	-0.6	1.2	2.0	0.5	2.6	2.1
Medication: Metformin	0.2	0.2	1.1	-0.1	0.2	-0.2	-0.3	-0.3	-0.3	-0.6	-0.9	0.7	-0.2	-0.2	-0.2	-0.4	-1.1	0.3	-0.4
Diabetes (father)	0.4	0.5	2.3	-0.6	-0.4	-0.3	-0.1	0.2	1.5	-0.1	-1.2	-1.5	1.0	-0.4	0.1	0.2	-0.1	0.6	-0.2
Diabetes (mother)	0.9	1.1	2.6	1.1	1.2	1.3	1.5	1.3	-0.1	1.5	0.1	0.6	-0.6	-0.6	1.6	1.4	-0.2	-1.1	0.7
Severe depression (siblings)	0.1	0.2	0.5	-0.1	0.3	0.3	0.3	-0.1	-0.2	0.6	0.6	-0.7	0.2	0.5	0.6	0.2	-0.1	-0.5	-0.2
Pack years adult smoking proportion	0.7	1.1	3.5	-0.7	-0.0	1.0	-1.1	-0.2	-1.4	-1.5	-0.6	-1.9	0.4	0.5	-0.4	0.7	-1.2	-1.1	-1.8
Impedance of leg (right)	1.5	7.2	56.2	-2.3	-0.0	-3.0	-1.2	3.0	3.8	-0.1	-1.1	-7.5	1.9	0.6	-1.2	-2.6	2.3	1.0	-1.3
Leg fat-free mass (left)	1.3	6.7	17.6	-1.8	-3.9	3.1	-4.2	-1.7	-1.2	-4.0	-2.2	1.9	0.9	-2.2	-1.0	2.9	-3.0	1.7	-2.3
Trunk fat percentage	0.7	2.9	6.4	-1.4	-2.2	2.0	-2.2	-0.4	-2.0	-1.9	-2.3	1.2	1.2	-1.1	-0.2	2.3	1.2	2.5	-0.9
Hand grip strength (right)	1.2	3.4	8.3	-2.6	-2.7	-0.5	-2.4	-1.0	2.1	-2.0	-0.9	-1.7	2.0	-2.9	-1.9	-0.1	-1.9	0.3	-1.4
Townsend deprivation index at recruitment	0.3	0.4	1.4	0.8	1.0	-0.0	1.2	0.3	0.3	0.6	-0.2	-0.4	-0.2	1.2	0.4	0.0	0.3	0.1	0.8
Current tobacco smoking	1.0	1.6	7.3	1.8	1.7	0.7	0.3	0.9	-0.6	-0.9	-0.4	-1.8	-2.2	2.7	1.1	0.7	0.6	0.0	-0.1
Average weekly fortified wine intake	0.9	1.1	6.4	0.4	1.0	-0.5	1.0	1.6	0.1	1.2	2.5	-0.4	-0.9	-0.0	0.6	-0.7	0.2	0.9	1.3
Maternal smoking around birth	0.9	1.3	7.4	0.6	1.1	1.4	0.2	1.4	-1.5	0.0	0.8	-0.6	-0.9	0.3	1.0	1.0	1.1	2.7	0.8
Fed-up feelings	0.6	1.1	5.0	0.2	0.7	-1.0	1.8	-0.1	0.6	2.2	0.6	0.3	0.4	-0.9	0.1	-1.4	1.3	-1.0	1.2
Frequency of unenthusiasm / disinterest in last 2 weeks	0.9	1.2	4.5	0.8	0.7	0.4	1.5	-0.1	-1.0	1.6	0.2	1.8	-0.5	1.2	0.9	0.5	2.1	0.4	1.4
Relative age voice broke	0.5	0.8	2.7	-0.9	-1.0	-0.6	-0.4	-0.7	-0.9	-0.1	-0.5	-1.3	1.6	-0.1	-1.1	-0.3	-0.8	-1.4	-1.0
Taking other prescription medications	0.6	0.8	3.3	-0.3	-0.8	0.6	-0.6	1.0	-0.3	-0.9	-1.8	1.1	0.4	-1.6	-0.1	0.7	-0.2	1.5	0.1
Age when periods started (menarche)	0.3	0.7	2.0	0.6	1.1	-0.3	0.9	0.4	1.4	0.9	0.2	-1.4	-0.0	0.1	0.5	0.5	1.1	1.1	0.6
Bilateral oophorectomy (both ovaries removed)	0.5	0.6	1.7	-1.3	-1.2	0.0	-1.1	-0.4	0.3	-0.4	0.3	-1.0	0.9	0.0	-0.2	-0.5	-0.9	-0.3	-1.2
Heel bone mineral density (BMD) T-score, automated (left)	1.0	2.2	9.7	0.2	-0.7	0.2	-1.1	3.1	-2.3	-0.8	0.3	3.0	-1.4	-1.4	0.3	-0.6	-1.8	0.6	0.4
Tinnitus: Yes, but not now, but have in the past	0.8	0.8	2.8	0.9	1.1	0.5	1.1	1.3	-0.8	0.5	0.4	1.0	-1.7	1.1	0.7	0.4	0.3	-0.5	1.0
Qualifications: CSEs or equivalent	0.5	0.7	2.4	1.1	0.1	0.0	-0.2	0.8	1.5	-0.1	-1.0	0.2	-0.8	-0.1	1.2	0.6	0.7	1.4	0.6
Serious illness, injury or assault to yourself	2.0	2.4	5.6	-2.1	-2.4	-0.4	-2.0	-1.6	-1.2	-1.5	-1.3	0.9	1.9	-0.5	-2.4	-0.5	-1.1	-1.0	-1.9
High blood pressure	0.8	2.4	11.0	-1.8	-2.2	0.7	-1.3	-0.1	-1.5	0.0	-3.3	1.7	2.1	-2.2	-0.4	0.4	-0.9	0.6	-0.8
Hayfever, allergic rhinitis or eczema	0.3	0.6	1.8	0.7	1.2	-0.2	1.0	-0.4	0.4	1.3	0.9	-1.1	0.2	-1.2	-0.6	0.1	-0.4	0.0	1.2
Multivitamins +/- minerals	0.9	1.2	4.1	-0.5	0.1	-1.1	1.1	-2.0	1.2	2.0	0.4	-0.4	0.3	-0.5	-0.5	-1.0	1.9	-1.0	0.4
Stomach or abdominal pain in last month	0.6	0.7	3.6	0.2	-0.0	0.5	-0.3	-0.5	0.4	-1.2	-1.9	1.2	0.7	1.6	-0.4	0.4	-0.4	0.2	-0.6
Supplements: Glucosamine	0.8	1.0	4.7	-0.5	-0.7	-0.2	0.1	-2.2	0.5	0.5	1.4	1.9	0.7	-1.1	-0.1	-0.6	1.3	-0.3	-0.6
Diverticular disease/diverticulitis (self-reported)	0.5	0.5	2.8	0.1	0.0	1.3	-0.5	0.2	0.6	-1.3	-0.9	-0.2	-0.5	0.2	0.3	1.7	-0.5	0.0	-0.5
Medication: Atenolol	1.2	1.5	4.3	1.4	1.0	1.4	0.7	1.7	-0.7	0.4	-0.8	2.1	-1.0	1.1	1.2	1.1	0.3	1.8	1.6
Medication: Levothyroxine sodium	0.3	0.5	2.0	0.7	0.1	0.4	0.9	0.2	0.0	0.9	-0.5	1.1	-0.9	-0.3	1.4	0.7	0.6	-0.2	0.9
Sitting height	1.8	13.1	43.8	-4.9	-5.2	0.8	-6.6	0.1	2.3	-5.2	-4.0	-2.6	3.1	-1.4	-2.1	0.6	-3.4	1.7	-5.2
Chronic bronchitis/emphysema (father)	0.6	0.7	2.0	0.1	0.1	1.2	0.4	0.4	-1.2	0.5	1.3	0.7	-0.1	-1.4	1.2	1.0	0.8	0.2	-0.1
High blood pressure (mother)	0.8	1.1	4.5	0.3	-0.6	-0.5	0.7	-1.4	0.2	1.8	-0.9	1.9	0.6	-2.1	0.7	0.1	1.1	-0.1	0.8
Body mass index (BMI)	1.2	5.3	18.0	1.2	-0.7	4.0	-1.2	-1.2	-4.2	-2.5	-1.6	4.2	-0.9	-0.5	0.6	3.9	-1.4	0.8	-0.2
Impedance of leg (left)	1.4	6.7	52.0	-2.2	0.1	-3.1	-0.9	3.2	3.5	0.4	-0.4	-7.2	1.9	0.2	-0.7	-2.6	2.3	0.7	-1.1
Leg predicted mass (left)	1.3	6.7	17.7	-1.7	-3.9	3.2	-4.2	-1.7	-1.2	-4.1	-2.2	1.9	0.9	-2.2	-1.0	3.0	-2.9	1.8	-2.3
Trunk fat mass	1.1	4.6	12.5	-2.0	-3.1	2.5	-3.5	-0.3	-1.9	-3.1	-2.7	0.9	1.3	-1.5	-0.6	2.6	-0.2	2.6	-1.8
Waist circumference	1.4	5.0	12.9	-1.0	-2.8	2.7	-3.5	0.0	-2.1	-3.6	-3.2	2.3	0.5	-0.9	-0.2	2.6	-1.2	2.5	-1.5
Number of incorrect matches in round	1.1	1.8	6.6	-2.3	-1.5	-1.0	-0.4	-1.2	-0.2	1.0	-0.1	-1.8	2.6	-1.5	-1.3	-0.9	-0.1	-1.3	-0.9
Past tobacco smoking	0.4	0.7	4.0	-0.1	-0.3	-1.7	-0.1	-2.0	-0.0	0.4	-0.3	0.4	0.2	-0.3	-0.9	-1.6	-0.5	-0.7	0.3
Alcohol usually taken with meals	1.7	2.8	7.4	2.7	1.9	0.4	1.9	-0.2	1.1	1.2	2.3	2.2	-2.1	0.9	1.9	0.7	1.4	1.0	2.2
Nervous feelings	0.7	1.2	5.8	-0.7	0.2	-1.1	1.7	-0.5	0.8	2.4	0.1	0.1	0.9	-0.8	0.4	-0.9	1.7	0.6	1.7
Frequency of tenseness / restlessness in last 2 weeks	1.3	2.0	7.1	-0.2	0.2	-1.1	1.9	-1.8	-0.4	2.7	1.2	1.9	1.4	1.3	-0.6	-1.4	2.0	-0.8	1.3
Hearing difficulty/problems with background noise	1.3	2.1	6.8	0.8	1.1	-1.6	1.9	0.1	1.2	2.4	0.7	0.9	-0.4	2.1	1.1	-1.6	2.6	0.1	1.3
Hair/balding pattern: Pattern 2	2.2	2.8	6.7	2.1	2.6	1.4	1.6	2.2	1.9	0.5	1.2	-1.6	-2.2	-0.7	2.4	1.5	0.8	0.7	1.2
Had menopause	2.7	3.3	11.5	-2.5	-2.7	1.5	-2.0	-1.5	-0.5	-0.8	-1.2	-1.6	3.1	-3.4	-1.7	1.1	0.4	1.1	-0.9
Had other major operations	0.6	0.8	2.9	-0.7	-0.5	0.5	-0.0	-0.2	-1.7	-0.3	-0.7	0.4	1.2	-0.7	-1.3	0.5	-0.8	-1.6	-0.7
Forced vital capacity (FVC)	2.4	9.1	28.7	-4.3	-5.1	-0.8	-5.4	-0.8	1.1	-4.0	-1.8	-2.2	2.9	-2.6	-2.6	-0.6	-2.5	0.9	-4.0
Heel bone mineral density (BMD) T-score, automated (right)	0.7	1.5	5.9	0.2	-0.8	0.2	-1.0	2.0	-1.8	-1.2	-0.2	2.4	-1.4	-1.1	0.0	-0.4	-2.2	0.4	0.3
Ever unenthusiastic/disinterested for a whole week	1.0	1.2	4.0	1.0	0.5	0.4	1.2	-1.5	-1.3	1.7	1.2	1.2	0.0	-0.6	0.4	1.2	2.0	-0.7	0.9
Qualifications: None of the above	0.3	0.6	2.1	-0.5	-0.1	1.3	-0.4	1.4	-1.1	-0.3	0.3	0.1	0.3	-0.5	0.5	1.1	-1.0	-0.8	-0.7
Financial difficulties in last 2 years	0.8	1.1	3.4	-0.3	-0.3	-1.4	-0.5	-1.2	1.0	-1.3	-1.1	-0.8	0.6	1.8	-1.1	-1.2	-0.6	-1.2	-1.1
Mouth/teeth dental problems	0.4	0.6	3.7	-0.3	-0.1	0.4	-0.5	0.8	1.9	-0.1	-0.8	-1.2	-0.2	-1.1	-0.2	0.7	-0.4	0.6	0.2
Heart attack	2.8	3.6	9.4	-2.5	-2.9	0.2	-3.1	-0.7	-1.5	-2.1	-1.8	1.9	2.4	-1.6	-1.8	-0.1	-1.9	0.8	-1.9
Allergy	0.3	0.7	1.4	-0.6	-1.1	-1.0	-1.0	-0.8	-0.8	-1.2	-0.8	0.2	0.0	0.7	-0.3	-1.2	-0.1	-0.7	-1.1
Pain all over the body in last month	0.7	0.8	2.5	1.2	0.8	0.4	0.0	0.9	0.0	-0.2	0.4	1.2	-1.4	0.9	0.4	0.7	0.6	1.6	1.1
Diabetes (self-reported)	0.2	0.4	1.6	-0.1	-0.2	0.2	-0.6	0.1	-0.2	-1.3	0.1	1.1	0.3	1.0	0.1	-0.0	-0.2	1.2	-0.5
Hayfever/allergic rhinitis (self-reported)	0.4	0.5	2.1	0.5	0.8	-0.4	1.2	-0.4	0.2	1.5	0.0	0.2	0.1	-1.0	-0.3	-0.6	-0.1	-1.1	0.9
Medication: Ramipril	2.5	3.3	6.2	-2.5	-2.4	-1.3	-2.1	-0.1	-2.0	-1.2	-2.2	1.4	2.0	-1.9	-2.1	-1.4	-2.1	-0.9	-1.7
Medication: Simvastatin	0.4	0.6	2.4	-0.3	-0.1	0.8	-0.3	1.5	-1.1	-0.0	-0.5	0.5	0.3	0.3	0.9	0.6	1.0	1.4	-0.1
Fluid intelligence score	0.4	0.8	1.7	1.3	0.9	-1.0	0.2	-0.1	0.6	-0.8	-0.7	1.0	-0.7	1.1	-1.3	-1.1	-0.0	0.7	1.1
Illnesses of siblings	0.6	0.9	2.7	1.0	1.3	-1.1	1.3	0.4	1.6	0.8	-0.1	-1.4	-1.0	-0.1	-0.2	-0.6	0.2	-0.6	0.8
Neuroticism score	0.7	1.4	6.0	-0.5	-0.0	-1.2	1.7	-1.6	0.5	2.4	0.3	0.7	1.5	-0.4	-0.2	-1.2	1.8	-0.2	1.3
Weight	1.7	8.2	23.6	-2.2	-4.0	3.6	-4.9	-0.9	-1.9	-4.8	-3.0	1.0	1.4	-1.8	-1.1	3.4	-2.6	2.0	-2.8
Impedance of arm (right)	0.9	4.2	17.5	-1.8	-0.6	-3.4	0.7	-0.1	3.1	2.2	0.4	-2.3	1.5	-0.4	0.0	-2.7	4.2	1.8	0.8
Arm fat percentage (right)	0.9	3.6	18.4	0.9	-0.7	2.5	-0.6	-1.2	-3.2	-1.4	-1.5	4.3	-0.5	-0.6	1.0	2.9	1.1	1.9	0.5
Trunk fat-free mass	1.3	7.3	23.0	-1.9	-3.5	3.2	-4.8	-0.6	-0.4	-4.8	-2.2	-0.2	0.8	-1.8	-1.1	2.7	-3.8	1.6	-3.1
Hip circumference	1.2	5.3	15.3	-0.7	-2.5	2.8	-3.2	-1.0	-2.3	-3.9	-3.8	1.2	0.6	-1.3	-0.8	3.1	-2.0	1.9	-1.6
Time employed in main current job	0.4	0.5	2.1	-1.0	-0.9	-0.2	-0.6	-0.3	-0.6	-0.2	0.5	-0.7	0.4	-1.5	-0.0	-0.4	-0.6	-0.8	-0.7
Alcohol intake versus 10 years previously	0.5	0.7	2.3	0.1	0.2	-1.1	0.1	-0.8	-0.9	0.3	0.4	1.5	-0.5	-1.3	-0.2	-1.2	-0.8	-1.5	-0.0
Father’s age at death	0.7	1.0	9.2	0.1	-0.0	-0.6	0.6	0.1	3.0	1.6	0.0	-0.7	-0.5	-0.4	0.2	-0.7	-0.1	0.1	1.3
Worrier / anxious feelings	1.2	2.2	12.8	-0.1	0.6	-1.1	2.1	-1.0	0.9	3.6	0.9	0.7	0.8	0.3	-0.2	-0.8	2.3	0.8	2.5
Frequency of tiredness / lethargy in last 2 weeks	0.2	0.4	2.4	0.2	-0.1	-0.3	0.5	-1.6	0.1	0.3	-0.7	-0.1	0.3	0.9	-0.3	-0.0	0.9	-1.1	-0.2
Falls in the last year	0.3	0.4	1.0	-0.2	-0.4	0.2	-1.0	0.2	-0.7	-1.0	0.7	-0.9	0.7	0.5	-0.6	0.2	0.1	0.1	-0.8
Hair/balding pattern: Pattern 3	2.3	3.4	10.6	-1.7	-1.7	-3.2	-0.7	-2.1	-1.2	0.1	-1.2	0.7	1.9	0.7	-3.0	-3.0	-0.7	-2.5	-1.1
Number of live births	1.1	1.5	3.7	1.4	1.4	0.4	1.9	-0.3	-0.7	1.7	0.5	1.9	-0.4	1.5	1.6	0.3	1.2	1.0	1.1
Forced expiratory volume in 1-second (FEV1)	2.7	9.1	28.8	-3.6	-4.8	-0.5	-5.4	-1.7	0.8	-4.4	-1.9	-2.8	2.7	-2.4	-2.9	0.0	-2.8	0.0	-4.2
Pulse rate	1.2	2.0	6.8	2.6	1.3	1.2	1.1	0.6	-0.5	0.1	0.5	2.6	-1.6	0.9	1.3	1.6	1.1	1.1	1.6
Happiness	2.6	3.2	13.9	0.3	0.2	-3.7	1.6	-2.0	0.8	2.4	-0.2	0.1	0.8	-0.4	-1.0	-3.4	1.0	-2.9	1.0
Noisy workplace	0.3	0.4	1.4	-0.3	0.3	1.1	0.5	-0.2	-0.7	0.3	1.2	-0.7	0.0	0.5	0.4	1.1	0.8	-0.0	-0.3
Qualifications: A levels/AS levels or equivalent	0.9	1.9	6.4	-0.3	-0.6	-2.5	0.4	-2.3	1.8	0.7	-0.1	-1.2	1.5	1.8	-1.8	-2.1	0.2	-0.9	-0.3
Serious illness, injury or assault of a close relative in last 2 years	0.1	0.1	0.5	0.2	-0.3	-0.6	0.1	0.4	0.5	0.4	0.4	-0.6	0.1	-0.0	-0.0	-0.7	-0.1	-0.4	0.2
Mouth/teeth dental problems: Dentures	0.3	0.5	2.5	0.2	0.0	-0.7	-0.1	0.7	-0.6	-0.4	1.6	1.2	0.0	1.0	0.4	-0.8	-0.8	-0.6	-0.3
Asthma	0.2	0.4	1.1	-0.6	-0.6	0.8	0.3	0.4	0.1	0.3	-0.9	0.8	0.5	1.0	0.6	1.0	0.6	0.5	-0.5
Medication: Ibuprofen (e.g. Nurofen)	0.7	0.8	4.3	0.3	0.5	-1.2	0.7	-2.1	0.8	0.4	-0.8	-1.1	0.4	1.1	-0.7	-0.3	0.4	-1.4	-0.2
Medication: Cholesterol lowering	1.6	2.4	5.4	-2.2	-2.3	-1.1	-1.9	-1.2	-1.7	-0.9	-1.3	0.1	2.3	-0.9	-1.9	-1.1	-1.1	-1.2	-1.9
Depression (self-reported)	0.6	0.7	2.1	-0.7	-0.6	1.1	-0.1	-1.4	-0.7	-0.3	0.4	-0.1	1.4	0.8	-0.1	0.6	0.5	-0.6	-1.5
Medication: Lansoprazole	1.3	1.5	4.9	-0.9	-1.8	0.4	-1.5	0.1	-1.0	-1.2	-1.1	0.4	1.1	-2.2	-0.2	0.4	-0.8	-1.5	-1.9
Prospective memory result	0.5	0.6	2.6	0.5	0.8	1.6	0.7	-0.3	-1.3	-0.0	0.6	-0.8	-0.5	-0.2	0.4	1.6	0.5	-0.5	0.2
Lung cancer (father)	0.6	0.7	2.7	0.2	0.1	1.1	-0.6	1.2	-0.6	-1.1	1.6	1.1	-0.3	0.5	1.1	1.1	-0.1	0.2	-0.8
Illnesses of mother	0.8	1.0	2.6	-0.8	-0.4	-1.4	-0.6	-0.9	-0.1	-1.0	-0.1	-1.2	0.7	1.5	-1.6	-1.5	-0.6	-0.9	-1.1
Forced expiratory volume in 1-second (FEV1), Best measure	4.1	13.0	38.7	-4.5	-5.5	-1.0	-6.2	-2.0	0.7	-5.3	-2.7	-3.1	3.4	-1.8	-3.6	-0.5	-3.4	-0.6	-5.4
Pulse wave Arterial Stiffness index	1.3	1.5	3.5	-1.5	-1.1	-1.6	-0.5	-0.7	0.4	0.6	-1.8	-0.7	1.5	-1.6	-1.9	-1.6	-0.2	-1.3	-0.6
Impedance of arm (left)	1.0	4.5	15.7	-2.1	-0.8	-3.4	0.1	0.5	3.6	1.7	-0.1	-3.0	1.6	-0.2	-0.4	-2.5	4.0	2.4	0.6
Arm fat mass (right)	1.1	4.6	11.3	-0.3	-2.1	3.2	-2.5	-1.2	-3.1	-2.9	-2.2	3.2	0.2	-1.2	0.1	3.4	-0.6	1.9	-0.9
Trunk predicted mass	1.3	7.4	23.2	-1.9	-3.6	3.2	-4.8	-0.6	-0.4	-4.8	-2.2	-0.1	0.8	-1.7	-1.1	2.8	-3.7	1.7	-3.1
Standing height	2.5	24.6	68.4	-7.7	-7.5	-0.5	-8.3	0.2	4.7	-5.1	-3.3	-6.7	5.2	-3.5	-3.9	-1.0	-2.9	2.9	-5.7
Length of working week for main job	1.1	1.2	6.9	0.4	-0.0	1.6	-0.2	-0.1	-2.6	-1.2	1.4	1.3	-0.0	-1.5	-0.0	1.5	-0.1	0.6	0.0
Exposure to tobacco smoke at home	0.7	0.8	4.1	-0.1	0.1	0.0	0.9	-1.6	-1.4	0.7	-0.5	2.0	0.6	0.7	-0.7	-0.3	-0.4	-1.0	0.3
Breastfed as a baby	1.0	1.2	3.3	-1.1	-1.0	-1.6	-0.7	-0.9	-0.9	-0.9	-1.6	0.8	1.2	-0.6	-1.8	-1.4	-0.9	-0.6	-0.9
Tense / ‘highly strung’	1.0	1.7	8.8	0.5	0.9	-0.1	2.3	-0.2	-0.1	3.0	0.1	0.6	0.5	0.5	0.3	0.0	2.4	0.4	2.3
Seen doctor (GP) for nerves, anxiety, tension or depression	0.3	0.5	2.0	-1.1	-0.5	1.0	0.5	-0.8	0.7	0.9	0.4	-0.5	1.4	-0.1	-0.6	0.8	0.7	-0.0	0.1
Hair/balding pattern: Pattern 4	0.5	1.3	2.9	-1.5	-1.6	1.0	-1.4	-1.3	-0.5	-1.5	-1.1	0.2	1.7	-1.1	-0.5	0.8	-0.7	1.3	-0.7
Birth weight of first child	4.9	8.8	20.5	-4.0	-3.5	-2.6	-3.6	-1.6	3.1	-2.4	-0.1	-4.5	4.1	-0.2	-3.1	-3.2	-1.8	-1.5	-3.6
Peak expiratory flow (PEF)	0.9	2.0	6.2	-1.1	-1.9	0.2	-2.1	-1.2	-1.4	-1.8	-0.5	-1.0	0.9	-1.0	-1.6	0.6	-2.5	-1.4	-1.5
Pulse wave reflection index	1.1	1.4	6.7	-0.5	0.2	-1.8	0.6	-0.3	2.6	1.7	-0.4	-1.5	0.6	-1.0	-0.5	-2.0	0.1	0.0	0.5
Ever highly irritable/argumentative for 2 days	0.8	1.0	5.5	0.6	0.6	0.2	1.0	-0.7	-2.4	1.2	1.5	-0.2	0.1	-0.5	-0.6	-0.0	1.1	-1.1	1.2
Loud music exposure frequency	0.5	0.5	2.0	-0.4	-0.0	-1.4	-0.4	0.4	1.4	-0.4	-0.7	-0.9	0.1	0.6	0.2	-0.9	0.4	1.0	-0.3
Qualifications: O levels/GCSEs or equivalent	0.7	1.0	6.0	0.5	-0.4	-1.0	-0.6	1.0	2.5	-1.2	-0.7	-1.0	-0.7	0.8	0.4	-0.5	-0.2	1.8	0.3
Mouth/teeth dental problems: Bleeding gums	0.7	0.9	3.7	0.8	0.0	0.9	0.3	-0.2	-1.7	-0.3	-1.9	1.7	-0.9	-0.1	0.7	1.0	-0.2	-0.8	-0.0
Blood clot in the leg (DVT)	0.4	0.5	1.1	0.9	0.7	0.8	0.5	1.0	-0.0	0.8	0.1	0.4	-0.9	0.4	0.5	0.7	0.6	0.6	1.0
Medication: Paracetamol	0.9	1.5	10.3	0.7	0.9	-0.9	0.6	0.1	3.2	1.0	0.3	-1.5	-0.9	0.3	0.8	-0.3	1.4	1.6	1.3
Headache pain in last month	0.4	0.6	3.1	0.5	0.7	-0.9	0.3	0.0	1.7	-0.5	0.2	-1.6	-0.4	1.4	0.4	-0.5	0.2	0.2	0.4
Medication for cholesterol, blood pressure or diabetes	0.3	0.6	1.6	0.7	0.9	0.9	0.4	0.3	1.3	-0.4	0.8	-1.3	-0.9	0.3	0.7	0.8	0.7	0.3	-0.0
Glaucoma (self-reported)	1.3	1.6	4.0	-1.0	-0.9	-1.4	-1.6	-0.9	-0.3	-2.0	-1.8	-1.4	1.0	-0.3	-1.9	-1.2	-0.3	0.3	-1.4
Gout (self-reported)	0.6	0.8	1.9	0.3	-0.4	1.0	-0.5	-1.4	-1.1	-1.3	-1.0	1.1	-0.1	0.2	1.3	1.2	-0.3	0.1	-1.3
Hypothyroidism/myxoedema (self-reported)	0.1	0.2	2.0	0.1	-0.7	-0.1	-0.4	-0.1	-0.5	-0.4	-1.4	-0.0	-0.5	0.2	0.3	0.3	0.3	-0.2	-0.3
Medication: Amlodipine	0.7	1.0	4.8	-0.2	-0.2	0.0	0.8	0.9	-1.0	2.2	0.5	0.9	0.2	-1.2	0.4	-0.1	1.2	1.1	1.9
Medication: Ventolin 100micrograms inhaler	0.4	0.6	1.9	-1.0	-1.0	0.8	-0.2	0.4	-0.2	0.4	-1.4	0.7	1.2	-0.9	0.1	1.0	-0.4	0.2	-0.3
Birth weight	2.2	4.8	10.8	-2.7	-3.3	-0.8	-2.8	-1.8	2.8	-2.7	-1.1	0.2	3.0	-1.7	-2.6	-0.9	-2.5	-0.6	-2.1
Chronic bronchitis/emphysema (mother)	1.3	1.5	8.0	0.4	0.1	2.8	-0.8	2.1	-1.0	-1.0	0.1	-0.8	0.1	-0.1	0.6	2.6	-0.1	1.1	0.0
High blood pressure (siblings)	0.5	0.7	2.9	-1.1	-1.0	-0.3	-0.1	-1.0	-1.3	0.7	-1.0	1.7	0.9	-0.4	-0.3	-0.8	-0.2	-0.8	-0.2
Forced vital capacity (FVC), Best measure	3.2	11.9	35.9	-4.8	-5.6	-1.4	-6.0	-1.2	1.2	-4.8	-2.4	-2.8	3.1	-2.0	-3.2	-1.1	-3.0	0.2	-4.9
Body fat percentage	0.7	2.7	7.0	-0.6	-1.6	2.3	-1.9	-0.4	-2.5	-2.2	-2.1	1.5	0.7	-0.6	0.1	2.6	0.9	2.1	-0.8
Leg fat percentage (right)	0.6	2.3	7.8	0.0	-0.8	2.4	-1.7	0.2	-2.8	-2.3	-2.2	0.5	0.3	-0.3	-0.1	2.6	0.0	0.9	-0.9
Arm fat-free mass (right)	1.4	7.2	22.0	-1.9	-3.3	3.4	-4.7	-0.2	-0.9	-4.7	-2.4	-0.3	0.9	-1.8	-1.2	2.9	-3.8	1.3	-3.1
Exposure to tobacco smoke outside home	0.4	0.6	1.7	0.5	0.7	0.3	0.4	0.8	0.5	-0.4	-0.2	1.1	-0.9	0.9	0.5	0.4	-1.3	-1.3	0.5
Comparative body size at age 10	1.4	3.8	22.9	1.2	-0.3	0.7	0.3	-4.1	-3.8	-1.0	0.3	4.8	0.1	0.8	-0.4	0.5	-0.6	-1.2	-0.1
Number of full brothers	0.4	0.5	1.7	1.1	1.1	-0.9	0.1	0.7	0.5	-0.4	1.3	0.3	-1.0	0.6	0.1	-0.2	0.5	0.6	0.6
Worry too long after embarrassment	1.0	1.7	4.6	-0.9	-0.2	0.2	1.3	-1.5	2.1	2.0	0.7	-0.5	1.3	-1.3	-0.1	0.2	2.1	1.7	1.6
Seen a psychiatrist for nerves, anxiety, tension or depression	0.8	1.1	5.4	0.6	0.9	0.1	1.7	-0.5	2.3	1.6	0.8	0.7	-0.2	-0.0	0.3	0.3	1.4	-0.0	1.3
Wheeze or whistling in the chest in last year	1.0	1.7	5.2	1.6	0.7	2.1	0.5	1.0	-0.6	-0.4	-0.0	2.0	-1.2	0.5	1.6	2.3	0.7	1.7	1.2
Number of children fathered	0.9	1.0	2.4	1.4	1.4	0.9	0.7	0.8	-1.0	-0.1	0.9	1.4	-1.6	1.0	1.0	1.2	0.1	0.6	0.7
Reason for reducing amount of alcohol drunk: Health precaution	0.6	0.7	4.2	-0.0	0.4	-0.7	0.5	-0.8	1.1	0.0	0.7	-0.4	-0.3	0.1	0.1	-0.9	2.0	1.3	0.3
Age at first live birth	0.7	1.2	5.4	-0.1	0.4	-1.4	1.2	0.9	1.2	2.3	0.4	-0.9	-0.5	-1.3	0.1	-1.3	1.0	0.4	1.5
Pulse wave peak to peak time	0.9	1.0	2.3	0.9	0.5	1.5	-0.2	0.8	0.1	-1.1	1.4	0.0	-1.1	1.3	1.5	1.5	-0.1	1.5	0.1
Health satisfaction	0.5	0.6	4.8	0.8	0.5	-0.5	1.2	-0.5	-0.4	0.5	0.1	2.2	-0.3	-0.2	0.5	-0.3	0.7	-0.2	0.8
Shortness of breath walking on level ground	0.5	0.6	2.3	-0.3	-1.3	0.5	-0.6	-0.8	-1.5	0.0	-0.1	1.3	0.5	1.0	-0.3	0.8	0.2	0.1	-0.3
Qualifications: College or University degree	0.6	2.0	6.6	-0.5	-0.3	-2.4	0.9	-2.6	2.1	1.3	0.1	-1.7	1.2	0.2	-1.3	-2.2	0.4	-1.3	-0.2
Eye problems/disorders: None of the above	1.1	1.3	3.4	1.2	0.9	-0.8	1.0	1.4	1.4	0.8	1.8	1.3	-1.6	0.4	0.6	-0.5	-0.2	-0.1	1.8
Mouth/teeth dental problems: Loose teeth	2.4	2.8	16.5	-0.0	-0.1	4.0	-0.5	0.6	-1.2	-1.4	-1.0	-0.0	0.1	0.7	1.0	4.1	1.1	2.2	-0.6
Emphysema/chronic bronchitis	2.1	2.3	8.3	0.1	0.2	2.9	0.6	1.8	0.6	0.6	0.9	1.2	0.1	-1.5	1.4	2.3	1.8	2.8	1.2
Medication for pain relief, constipation, heartburn	0.8	1.3	5.0	-0.4	-0.9	1.0	-1.3	0.7	-1.5	-2.2	-1.5	0.9	0.2	0.1	-0.6	0.3	-2.2	-0.2	-1.4
Neck or shoulder pain in last month	1.3	1.8	5.8	-1.2	-1.3	1.1	-2.0	-0.5	-1.4	-2.3	-2.2	-0.4	1.2	-0.2	-0.2	1.1	-0.1	0.2	-2.4
Medication: Blood pressure	0.2	0.4	1.4	0.1	-0.1	-0.7	-0.3	0.9	-0.8	0.3	-0.6	1.2	0.1	0.7	-0.0	-0.8	-1.0	0.5	0.7
Angina (self-reported)	0.6	0.8	6.1	-0.2	-0.3	1.0	-0.7	1.0	-0.6	-0.8	-0.6	2.5	0.2	-0.3	0.5	1.1	-0.4	0.9	-0.4
Migraine (self-reported)	0.6	0.7	2.2	-1.0	-0.8	-0.4	-1.2	0.2	1.5	-0.8	-1.0	-0.9	1.5	-0.5	-0.2	-0.1	-0.1	0.4	-1.1
Medication: Ibuprofen	1.1	1.3	3.4	1.1	1.4	-1.2	1.9	-1.7	0.8	1.6	0.9	-0.1	-0.5	1.4	0.1	-0.5	1.0	-1.2	1.0
Medication: Allopurinol	0.7	1.0	7.1	0.5	-0.2	0.7	0.3	-2.7	-0.5	0.1	-0.3	0.7	-0.0	1.2	1.6	0.9	0.6	-0.9	-1.0
Medication: Omeprazole	0.1	0.1	0.7	-0.3	0.1	0.1	-0.3	0.3	-0.9	-0.0	0.5	-0.2	0.1	0.2	-0.6	-0.2	0.2	0.1	0.2
Medication: Seretide 50 evohaler	1.0	1.1	4.4	0.2	-0.0	2.0	-0.8	1.9	-0.2	-1.4	-0.4	-0.7	0.0	-0.2	0.8	2.1	-1.1	0.4	-0.6
Mean time to correctly identify matches	0.8	1.4	4.8	-1.4	-0.8	1.0	-0.6	2.2	1.2	0.2	-2.2	0.0	0.6	0.9	0.4	1.3	1.0	2.1	0.0
Heart disease (mother)	0.8	1.0	4.1	-0.3	-0.8	1.6	-1.3	1.4	0.7	-0.7	-1.0	0.8	0.2	0.1	0.6	1.6	0.1	2.0	-0.2
Reproduciblity of spirometry measurement using ERS/ATS criteria	1.9	2.2	6.7	1.7	1.9	-1.1	2.6	-0.8	0.4	1.7	0.8	2.5	-1.1	2.0	0.4	-0.7	1.4	-0.5	1.5
Whole body fat mass	1.0	4.4	10.3	-1.2	-2.6	2.8	-3.2	-0.5	-2.5	-3.2	-2.4	1.6	0.8	-1.2	-0.3	3.0	-0.4	2.2	-1.5
Leg fat mass (right)	1.0	3.9	10.2	-0.7	-2.1	3.0	-3.0	-0.1	-2.7	-3.2	-2.2	1.2	0.6	-1.1	-0.3	3.0	-1.0	1.6	-1.4
Arm predicted mass (right)	1.6	8.0	24.9	-2.1	-3.6	3.5	-5.0	-0.2	-0.9	-5.0	-2.5	-0.5	0.9	-1.6	-1.1	3.0	-3.7	1.5	-3.4
Pulse rate, automated reading	0.9	3.0	6.8	2.4	2.1	1.7	2.0	1.6	-1.7	1.1	1.8	2.3	-1.5	-0.1	1.2	1.7	1.4	0.8	2.6
Alcohol intake frequency.	0.5	1.3	3.8	-1.6	-2.0	0.1	-1.5	-0.9	-0.6	-0.3	-0.9	0.4	1.8	-1.9	-0.7	0.4	0.4	-0.5	-1.0
Comparative height size at age 10	2.9	15.9	45.8	-6.4	-6.4	-0.1	-6.8	-0.4	3.6	-4.0	-3.3	-3.5	4.1	-3.4	-3.7	-0.8	-2.5	2.6	-4.2
Number of full sisters	0.6	0.7	3.4	-0.4	-1.2	-0.8	-1.5	-0.5	0.4	-1.4	0.0	0.0	-0.0	-0.0	-0.7	-0.7	-1.8	-0.2	-0.7
Suffer from ‘nerves’	0.2	0.4	2.1	-0.8	-0.3	-0.6	0.1	-0.1	-0.4	0.2	-0.8	1.5	1.1	-0.1	-0.2	-0.3	0.4	0.3	0.0
Overall health rating	0.4	0.8	7.5	0.4	-0.0	1.2	0.0	0.4	-1.0	-0.3	-1.0	2.7	0.1	0.0	0.4	1.3	-0.1	-0.0	0.1
Chest pain or discomfort	0.9	1.2	5.1	0.6	0.2	1.3	-0.3	1.6	0.1	-1.2	-0.8	2.0	-0.7	0.7	0.6	1.4	0.6	2.2	0.8
Had major operations	0.8	0.9	2.9	-0.7	-0.9	-1.5	-0.8	-0.8	0.8	-1.1	-0.9	1.3	0.3	0.0	-1.7	-1.3	-0.1	-0.4	-0.6
Age at last live birth	0.8	1.2	4.2	0.3	0.6	-0.1	1.0	2.0	1.0	2.0	0.4	-1.6	-0.9	-0.7	1.1	0.3	1.4	0.8	1.0
Family relationship satisfaction	1.0	1.2	4.1	-1.0	-0.4	-1.5	0.6	-1.5	2.0	1.6	-0.2	-0.7	1.2	-0.7	-0.9	-1.1	0.3	-1.6	-0.0
Leg pain on walking	0.4	0.5	3.2	0.5	0.2	0.2	0.8	-1.8	-1.3	0.1	-0.1	1.3	0.1	0.1	-0.0	0.6	0.4	-0.9	0.2
Qualifications: NVQ or HND or HNC or equivalent	1.3	1.6	6.8	-0.3	-0.4	1.4	-1.9	0.5	-1.3	-2.6	-0.5	-0.1	0.5	-1.2	-0.6	1.7	-1.9	-0.2	-1.3
Commuting to job workplace: Car/motor vehicle	0.5	0.6	2.7	-0.6	-0.8	-0.4	-0.8	-0.8	-0.8	-1.6	-0.3	0.8	0.2	-0.6	-0.2	-0.5	-1.1	-0.5	-1.0
Illness, injury, bereavement, stress in last 2 years	0.3	0.4	2.0	-1.1	-0.1	0.0	-0.1	0.1	-0.5	0.5	1.1	-0.9	0.4	-1.4	-0.6	-0.3	-0.2	-0.6	-0.3
Medication: Aspirin	0.2	0.3	0.9	-0.7	-0.7	0.2	-0.5	-0.1	-0.9	0.1	-0.4	1.0	0.6	-0.8	0.5	-0.1	0.7	0.5	-0.5
Supplements: Vitamin C	0.4	0.4	2.6	-0.0	0.1	0.3	0.8	0.1	0.7	0.8	0.5	-0.7	0.5	-0.4	0.8	0.5	0.2	-1.6	-0.5
Knee pain experienced in last month	1.3	2.0	9.0	-0.4	-0.7	-0.6	-0.3	-3.0	-1.9	-1.0	-0.0	1.6	1.4	0.5	-1.6	-0.8	-1.0	-2.4	-1.4
Hypertension (Self-reported)	0.7	1.8	7.9	-1.4	-1.9	0.9	-1.0	-0.2	-1.2	0.5	-2.8	1.8	1.8	-2.0	0.0	0.6	-0.4	0.9	-0.1
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.3	0.3	1.4	-0.7	-0.5	-0.0	-0.2	-0.3	0.0	0.3	0.3	-0.9	-0.0	-1.2	-0.2	0.1	0.9	-0.9	-0.6
Illnesses of father: Heart disease	0.6	0.8	4.1	-0.8	-0.8	0.5	-0.3	0.7	0.0	0.6	-0.9	2.0	1.0	0.5	-0.6	-0.2	0.7	1.9	0.3
Illnesses of siblings: Diabetes	0.5	0.6	2.6	0.2	0.0	-0.0	-0.8	-1.4	-0.4	-1.4	1.6	0.5	-0.3	-0.7	-0.0	-0.4	-0.3	0.4	-0.6
Smoking status: Previous	0.6	0.8	5.1	-0.6	-0.5	1.5	-0.3	2.3	-0.2	-0.1	0.7	0.5	0.4	-0.2	0.8	1.4	0.3	1.2	-0.1
Forced expiratory volume in 1-second (FEV1), predicted	2.1	4.4	11.4	-2.6	-2.3	-0.7	-3.4	0.3	2.8	-3.0	-1.3	-3.2	1.6	-1.1	-1.5	-0.4	-2.0	0.4	-2.7
Whole body fat-free mass	1.3	7.4	21.9	-1.9	-3.8	3.4	-4.7	-1.1	-0.8	-4.6	-2.2	0.6	0.9	-2.0	-1.1	2.9	-3.6	1.7	-2.9
Leg fat-free mass (right)	1.1	6.0	15.3	-1.6	-3.7	3.0	-3.9	-1.8	-1.2	-3.6	-1.6	2.1	0.9	-2.5	-0.8	2.7	-3.0	1.5	-2.1
Arm fat percentage (left)	0.9	3.6	15.8	0.7	-0.9	2.6	-0.9	-1.1	-3.2	-1.6	-1.6	4.0	-0.4	-0.3	0.8	3.0	1.0	2.1	0.3
Average weekly red wine intake	1.1	1.6	10.8	0.9	0.3	0.2	0.1	0.3	2.4	0.0	-0.0	0.2	-1.4	0.8	1.6	0.6	1.1	3.3	1.1
Handedness (chirality/laterality): Left-handed	0.6	0.7	2.3	0.9	1.5	0.1	1.3	0.3	1.5	0.7	1.3	0.3	-0.4	1.0	0.5	-0.1	0.4	-0.1	0.5
Mood swings	1.3	2.4	9.3	0.5	0.9	-1.3	2.6	-1.6	0.4	3.1	0.7	2.0	1.4	-0.9	-0.3	-1.1	2.2	-0.6	1.5
Loneliness, isolation	0.2	0.2	0.7	-0.3	-0.2	-0.8	0.1	-0.2	0.6	0.2	-0.5	0.8	0.4	0.6	-0.1	-0.6	0.9	0.1	0.2
Long-standing illness, disability or infirmity	0.4	0.6	3.1	-0.3	-0.5	0.3	-0.5	0.1	0.3	-0.9	-0.6	1.8	0.5	-0.7	-0.4	0.2	-1.6	-0.6	-0.6
Ever had bowel cancer screening	0.4	0.5	3.1	-0.6	-0.7	0.8	-0.1	0.8	-0.5	0.2	1.0	0.5	0.6	0.3	-0.2	0.4	0.6	1.8	0.8
Diabetes diagnosed by doctor	0.3	0.4	1.6	0.2	0.4	0.1	-0.7	0.4	-1.0	-1.3	-0.5	1.1	-0.2	0.8	0.2	-0.0	-1.0	0.3	-0.6
Ever had stillbirth, spontaneous miscarriage or termination	3.6	3.8	9.9	1.5	2.2	0.3	2.6	1.7	0.2	3.1	1.1	2.4	-2.0	1.9	2.0	0.2	2.4	1.3	2.8
Friendships satisfaction	2.6	3.2	12.6	0.1	0.4	-3.5	1.9	-2.5	0.5	3.2	-0.0	0.3	1.0	-0.4	-0.4	-2.9	1.8	-2.3	0.8
Qualifications: nursing, teaching	1.0	1.6	4.0	1.5	1.5	-1.6	2.0	-1.4	1.2	1.1	0.5	0.9	-1.0	1.5	-0.4	-1.3	0.2	-1.1	1.3
Commuting to job workplace: Walk	0.6	0.6	2.8	-0.2	-0.0	0.7	0.0	0.6	1.2	0.7	0.0	-1.7	0.9	-1.4	-0.2	0.7	0.4	0.8	0.7
Eye problems/disorders: Cataract	1.3	1.5	3.7	-1.2	-1.2	1.9	-0.4	-1.9	-0.9	-0.2	-1.0	-0.8	1.9	-0.5	0.3	1.7	1.5	0.4	-1.6
Mouth/teeth dental problems: Mouth ulcers	0.6	0.9	2.7	-0.4	0.1	1.1	0.5	-1.6	-1.0	0.8	1.3	-1.2	1.6	0.5	-0.3	0.2	1.6	0.2	-0.3
Medication for cholesterol	0.9	1.3	7.8	1.2	1.8	-0.6	1.0	0.9	0.7	0.2	1.4	-1.4	-1.0	2.8	0.5	-0.3	0.5	-0.2	0.4
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.5	0.6	3.4	-0.4	-0.7	0.7	-0.5	1.3	-1.8	-0.2	0.1	-0.3	1.1	-0.0	-0.6	0.6	-0.8	-0.9	-0.2
Back pain experienced in last month	0.4	0.5	2.7	-0.5	-0.5	-0.2	-0.9	1.0	-0.5	-0.8	-1.6	-0.7	0.5	-0.5	-0.2	0.0	-0.1	-0.5	-1.0
Mineral and other dietary supplements	1.4	1.8	7.7	1.6	0.8	0.8	-0.7	2.8	-1.5	-1.9	-1.0	1.0	-1.6	1.2	1.1	1.2	-1.0	1.2	0.2
Breast cancer (self-reported)	3.4	4.0	9.5	2.4	2.1	2.0	2.7	0.9	-0.9	2.2	1.0	3.1	-2.0	-0.3	2.4	1.4	2.5	1.1	2.7
Asthma (self-reported)	0.2	0.4	1.5	-0.7	-0.7	0.6	0.3	0.4	0.5	0.4	-1.2	0.8	0.6	0.7	0.5	0.9	0.5	0.6	-0.5
Osteoporosis (self-reported)	1.9	2.3	8.0	-2.3	-2.1	-0.2	-1.1	-1.2	1.5	0.5	-1.7	-2.8	2.3	-1.4	-0.9	-0.1	1.5	0.7	-0.6
Osteoarthritis (self-reported)	0.2	0.3	1.9	0.4	0.1	0.7	0.1	-0.3	-1.4	-0.3	0.5	0.6	-0.4	0.4	0.2	0.3	0.3	-0.7	-0.3
Medication: Aspirin	0.3	0.4	1.1	-0.6	-0.4	0.6	-0.1	0.1	-0.5	0.6	-0.6	1.0	0.3	-0.4	0.8	0.3	1.0	1.1	-0.0
Medication: Gliclazide	1.1	1.2	3.6	-0.5	-0.6	1.1	-1.4	-0.9	-1.4	-1.9	-1.4	1.2	1.0	0.6	0.0	1.1	-0.8	0.1	-1.7
Illnesses of father: None of the above (group 1)	1.3	1.6	5.5	1.5	1.2	-1.2	0.4	-0.7	-1.5	-1.1	0.8	-1.3	-1.5	2.1	0.2	-0.8	-1.1	-2.3	-0.5
Smoking status: Current	0.9	1.5	5.9	1.8	1.7	0.1	0.4	0.9	-0.4	-0.7	-0.5	-2.0	-2.3	2.4	0.8	0.2	0.3	-0.6	0.0
Forced expiratory volume in 1-second (FEV1), predicted percentage	2.2	4.6	13.0	-2.4	-3.6	-0.0	-3.6	-0.7	-1.2	-3.0	-2.3	0.0	2.2	-1.7	-1.9	0.3	-2.3	-0.3	-3.0
Whole body water mass	1.3	7.4	22.1	-1.9	-3.9	3.2	-4.7	-1.2	-0.8	-4.6	-2.3	0.7	0.9	-1.9	-1.1	2.8	-3.6	1.6	-3.0
Leg predicted mass (right)	1.1	5.9	14.9	-1.5	-3.6	3.0	-3.9	-1.6	-1.2	-3.6	-1.6	2.2	0.7	-2.4	-0.7	2.8	-3.0	1.6	-2.0
Arm fat mass (left)	1.1	4.4	10.8	-0.2	-2.1	3.2	-2.5	-0.8	-2.8	-3.0	-2.2	3.0	0.1	-1.1	0.2	3.3	-0.7	2.0	-0.9
Number of self-reported non-cancer illnesses	1.2	2.1	5.0	-2.2	-2.2	0.6	-1.7	-0.1	-0.6	-1.3	-2.2	0.5	2.2	-1.7	-1.3	0.3	-0.1	0.3	-1.6
Average weekly champagne plus white wine intake	0.4	0.6	1.9	-0.0	0.0	-1.1	0.9	-0.3	-0.1	1.4	0.5	1.0	-0.0	-0.5	-0.8	-1.2	0.3	-0.5	1.2
Miserableness	0.6	1.1	3.3	1.0	1.2	-0.8	1.8	-1.3	0.2	1.5	0.5	1.0	-0.5	0.9	0.7	-0.8	1.6	-0.1	1.2
Guilty feelings	2.0	2.9	13.0	1.1	1.0	1.5	1.9	0.2	0.3	2.4	0.9	1.3	-0.1	1.2	1.5	1.2	3.6	2.7	2.5
Wears glasses or contact lenses	1.2	1.4	4.3	-1.9	-1.6	0.2	-1.2	-0.4	-0.3	-1.0	-0.4	-1.2	1.9	-2.1	-1.3	0.0	-0.3	0.9	-1.2
Ever taken oral contraceptive pill	0.6	0.7	2.1	-0.1	0.0	-1.5	-0.3	1.1	1.2	0.4	0.7	0.3	0.0	-1.1	0.2	-1.3	-1.2	-1.0	0.1
Hearing aid user	2.4	2.7	7.4	-2.3	-2.3	-0.7	-2.1	0.7	0.5	-1.1	-2.7	-1.7	1.7	-2.6	-1.5	-0.9	-0.9	0.7	-1.2
Mother’s age at death	0.2	0.3	0.8	-0.8	-0.2	0.1	0.4	-0.4	-0.1	0.8	-0.1	-0.9	0.3	-0.4	-0.5	-0.0	0.7	-0.9	0.2
Financial situation satisfaction	1.2	1.5	6.2	1.1	0.8	-2.5	1.0	-0.7	-0.5	1.3	-0.9	1.0	-0.5	0.8	-0.7	-2.1	-0.6	-2.1	0.7
Tinnitus: Yes, now most or all of the time	1.7	2.0	8.0	-0.1	-0.7	-0.6	-0.8	-2.5	-2.8	-0.9	0.0	0.9	0.7	0.0	-0.2	-0.9	-1.4	-2.6	-2.0
Commuting to job workplace: Public transport	0.8	1.0	3.5	0.5	0.5	-0.0	1.3	0.5	1.7	1.8	0.5	-0.3	-0.1	-0.1	0.8	0.3	1.9	1.1	1.3
Eye problems/disorders: Glaucoma	1.0	1.2	4.8	-0.4	-0.4	-0.7	-1.5	-0.7	-1.5	-2.2	-1.4	-0.8	0.6	0.1	-1.5	-0.7	-0.7	-0.2	-1.6
Medication: Blood pressure	0.7	1.3	5.2	-1.0	-1.5	0.4	-0.7	-1.4	-1.3	0.5	-2.3	2.2	0.8	-1.4	-0.3	-0.1	-0.3	-0.4	-0.3
Pain type(s) experienced in last month: Hip pain	0.6	0.7	2.1	-0.2	0.3	-0.5	-0.4	-0.3	-1.3	-1.4	1.0	-1.4	0.4	1.4	-0.2	-0.4	-0.6	-0.6	-0.9
Supplements: Fish oil (including cod liver oil)	0.9	1.1	5.9	-0.6	0.4	0.1	1.6	-1.3	1.5	2.4	1.2	0.2	0.5	-0.7	0.4	-0.3	1.6	-0.5	0.5
High cholesterol (Self-reported)	0.3	0.5	2.4	-0.3	-0.4	0.5	0.5	-0.4	-0.2	1.1	0.0	0.8	0.3	-0.7	0.6	0.7	1.5	0.9	0.4
Medication: Bendroflumethiazide	0.4	0.6	2.6	-0.3	-0.4	0.8	-0.0	0.1	-0.2	1.0	-1.1	1.0	0.4	-1.6	1.0	0.7	0.6	1.2	0.0
Medication: Paracetamol	1.0	1.6	11.3	0.8	1.0	-0.7	0.5	0.8	3.4	0.7	0.9	-1.0	-1.2	0.4	1.1	-0.0	1.0	1.8	1.5
Medication: Lisinopril	1.6	2.1	4.7	1.2	1.1	1.5	1.7	0.5	2.0	1.7	1.1	0.2	-1.4	-0.8	2.2	1.0	2.1	1.3	1.8
Medication: Atorvastatin	0.8	0.9	3.2	-0.9	-1.0	-0.5	-1.1	-1.2	0.3	-0.5	-0.5	-0.5	1.0	-1.8	-0.8	-0.4	-1.3	-1.4	-1.1
Illnesses of father: High blood pressure	0.5	0.6	2.7	-0.3	-0.3	-0.4	0.5	-1.6	1.0	0.6	0.2	0.9	1.2	-1.0	-1.2	-0.2	-0.2	-0.1	0.6
Alcohol drinker status: Never	0.4	0.4	2.1	-0.0	-0.3	0.9	-0.6	-0.6	-1.2	-0.7	0.1	-0.5	0.8	-0.2	0.3	1.4	0.5	0.3	-0.5
Ever smoked	0.4	0.7	2.9	-0.3	0.0	1.7	0.0	0.7	0.9	-0.5	-0.2	-1.6	0.3	0.2	0.7	1.5	0.8	0.0	-1.1
Basal metabolic rate	1.4	7.8	23.5	-2.0	-3.9	3.4	-4.8	-1.0	-1.0	-4.7	-2.5	0.7	1.0	-2.0	-1.1	3.1	-3.5	1.8	-3.0
Leg fat percentage (left)	0.6	2.2	10.3	0.2	-0.6	2.5	-1.4	0.3	-3.2	-2.0	-1.7	1.0	0.1	-0.4	0.3	2.7	0.1	0.7	-0.7
Arm fat-free mass (left)	1.6	7.9	24.1	-1.8	-3.5	3.8	-4.7	-0.9	-1.1	-4.9	-2.8	0.2	1.0	-1.9	-1.0	3.3	-3.5	1.5	-3.2
Number of operations (self-reported)	1.0	1.5	3.0	-1.3	-1.7	-0.3	-1.4	-0.5	-0.8	-1.4	-1.7	1.1	1.0	-0.6	-1.6	-0.5	-1.3	-1.6	-1.4
Average weekly beer plus cider intake	1.2	1.7	8.9	-0.4	-0.5	1.7	-1.4	0.8	-3.0	-1.6	-1.2	-0.4	0.3	0.4	-0.5	1.6	-1.7	-1.0	-1.3
Irritability	1.4	2.4	7.0	-1.2	-0.7	-1.2	-0.2	-2.6	-1.7	-0.7	-0.5	-1.6	2.1	0.9	-2.3	-1.2	0.4	-2.1	-2.0
Risk taking	0.5	0.8	2.6	0.1	-0.2	0.7	-0.3	-1.6	0.2	-1.2	-0.5	-0.5	0.8	1.0	-0.5	1.5	-0.3	-1.1	-1.2
Ever had prostate specific antigen (PSA) test	0.5	0.5	2.2	-0.9	-0.7	0.4	0.3	-0.7	-0.7	1.5	0.0	-0.2	1.2	-1.2	-0.3	0.6	0.5	0.1	0.3
Fractured/broken bones in last 5 years	0.9	1.1	7.2	-0.2	-0.8	-1.1	0.3	-2.7	0.3	0.2	-1.5	0.2	0.2	1.0	-0.6	-0.9	2.0	0.3	-0.1
Age started oral contraceptive pill	0.6	0.8	2.5	1.0	1.2	-0.2	1.2	0.4	-0.2	1.6	1.2	-0.0	-0.6	-0.8	0.5	-0.1	0.9	0.3	1.4
Diastolic blood pressure, automated reading	1.1	3.5	7.3	-1.1	-1.7	2.5	-1.5	-0.1	-1.1	-2.1	-2.7	2.6	1.8	-2.7	-0.3	2.7	0.0	2.3	-0.6
Ever depressed for a whole week	1.0	1.3	6.6	0.6	1.0	-0.1	2.0	-0.8	-0.8	2.6	0.8	0.3	0.6	-0.0	0.3	-0.1	1.4	-2.0	0.8
Unable to work because of sickness or disability	0.4	0.5	2.8	-0.3	0.0	0.2	-0.4	1.6	0.3	0.1	0.2	0.1	-0.1	1.2	0.3	0.1	1.7	1.3	-0.1
Commuting to job workplace: Cycle	1.3	1.6	7.5	0.1	0.1	-1.5	0.3	-2.7	-1.5	0.9	1.2	1.0	1.1	1.2	-1.1	-1.6	0.7	-1.7	-0.8
Myopia	0.8	1.2	5.0	-0.9	-0.1	-2.1	0.8	0.3	1.2	2.1	-0.2	-0.7	0.5	-0.5	-0.4	-2.2	0.5	-0.4	0.6
Vascular/heart problems diagnosed by doctor	1.2	3.2	11.8	2.0	2.6	-1.0	1.9	-0.1	2.1	0.6	3.4	-2.1	-2.4	2.3	0.5	-0.7	1.4	-0.4	1.1
Cholesterol lowering medication	0.8	1.1	2.4	1.1	1.1	0.7	0.7	1.1	-0.3	0.8	0.6	1.6	-1.2	0.1	1.6	0.8	1.2	1.5	1.1
Medication: Omeprazole (e.g. Zanprol)	0.3	0.3	1.0	0.3	0.4	0.5	0.4	0.9	-0.4	0.8	0.5	-0.3	-0.4	-0.4	0.2	0.4	0.8	0.4	1.0
Pain experienced in last month	0.3	0.5	2.2	-0.1	-0.0	-0.2	0.8	-1.1	0.5	1.5	1.4	-0.3	0.2	-0.2	-0.4	-0.2	0.2	0.1	0.8
Supplements: Calcium	1.1	1.2	4.8	-1.8	-1.5	0.3	-0.4	-2.2	0.2	0.8	-0.3	-1.7	1.5	0.1	-0.4	0.6	1.3	0.3	-0.7
Basal cell carcinoma (self-reported)	0.5	0.6	4.6	0.6	-0.1	0.1	-0.2	2.1	0.7	-0.2	-0.9	-0.1	-0.6	0.6	0.4	0.7	-1.2	-0.5	0.1
Heart attack/myocardial infarction (self-reported)	2.8	3.6	9.7	-2.5	-3.0	0.3	-3.1	-0.7	-1.5	-2.2	-1.9	1.8	2.4	-1.4	-1.8	0.2	-1.6	1.1	-1.9
Deep venous thrombosis (DVT) (self-reported)	0.5	0.6	1.8	1.1	0.8	0.9	0.6	1.4	-0.2	0.7	-0.1	0.4	-1.0	0.3	0.8	0.8	0.8	0.7	1.1
Heart disease (siblings)	0.9	1.1	2.3	-1.4	-1.3	0.1	-1.4	-0.8	-1.4	-1.0	0.2	1.5	1.0	0.1	-1.4	-0.2	-1.2	-0.3	-1.2
Alcohol drinker status: Previous	2.7	3.1	9.6	-3.1	-3.1	-0.7	-2.6	-0.7	-0.3	-0.9	-1.9	-0.5	2.3	-2.2	-2.0	-0.8	-0.2	0.2	-1.7
Pack years of smoking	0.6	0.9	3.1	-0.8	-0.1	0.4	-1.0	-0.3	-1.4	-1.0	-0.5	-1.8	0.5	0.4	-0.6	0.2	-1.1	-1.3	-1.5
Impedance of whole body	1.2	6.1	26.2	-2.3	-0.2	-3.9	-0.1	2.0	3.9	1.5	-0.5	-5.1	1.8	0.0	-0.5	-3.2	3.6	1.5	-0.0
Leg fat mass (left)	1.0	4.1	10.2	-0.6	-2.1	3.1	-2.9	-0.2	-3.0	-3.2	-2.0	1.4	0.6	-1.2	-0.2	3.2	-1.0	1.6	-1.4
Arm predicted mass (left)	1.4	7.0	21.1	-1.6	-3.3	3.5	-4.5	-0.8	-1.3	-4.6	-2.4	0.4	0.9	-1.8	-0.9	2.9	-3.5	1.1	-3.1