[Hub]/) : Traits : Comparative height size at age 10 :

chr16:88,074,533-90,172,696

Best TWAS P=3.12e-14 · Best GWAS P=1.05e-11 conditioned to NaN

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex CDK10 0.27 0.14 lasso 9 0.21 6.9e-25 6.46 -5.2 1.6e-07 -0.11 0.00 1.00 FALSE
2 CommonMind Brain Pre-frontal Cortex CTU2 0.10 0.07 lasso 5 0.08 4.0e-10 -5.39 5.7 1.2e-08 -0.43 0.94 0.06 FALSE
3 GTEx Adipose Subcutaneous CHMP1A 0.29 0.07 enet 35 0.12 2.0e-10 4.36 5.2 2.5e-07 -0.07 0.23 0.56 FALSE
4 GTEx Adipose Subcutaneous CDK10 0.37 0.20 enet 50 0.26 4.0e-21 1.49 -5.5 3.1e-08 -0.21 0.39 0.61 FALSE
5 GTEx Adipose Visceral Omentum CDK10 0.43 0.19 lasso 6 0.32 3.6e-17 6.46 -5.8 5.4e-09 -0.19 0.00 1.00 TRUE
6 GTEx Adrenal Gland URAHP 0.22 0.04 enet 16 0.17 8.2e-07 -3.67 -5.4 6.1e-08 0.11 0.11 0.13 TRUE
7 GTEx Artery Aorta VPS9D1 0.12 0.00 enet 21 0.06 5.0e-04 6.40 5.5 2.9e-08 0.03 0.03 0.71 FALSE
8 GTEx Artery Aorta CHMP1A 0.38 0.00 enet 32 0.30 1.2e-16 -0.62 6.0 2.1e-09 -0.03 0.08 0.35 TRUE
9 GTEx Artery Aorta CDK10 0.33 0.07 enet 27 0.18 2.7e-10 6.41 -6.0 2.5e-09 -0.20 0.00 1.00 FALSE
10 GTEx Artery Tibial CHMP1A 0.21 0.06 enet 34 0.11 7.3e-09 4.36 6.5 7.3e-11 -0.09 0.07 0.40 TRUE
11 GTEx Brain Cerebellar Hemisphere CDK10 0.62 0.20 enet 33 0.28 6.4e-08 6.46 -5.4 5.6e-08 -0.21 0.00 1.00 FALSE
12 GTEx Brain Cortex URAHP 0.34 0.19 enet 15 0.17 2.4e-05 -3.67 -5.4 6.6e-08 0.15 0.38 0.13 FALSE
13 GTEx Cells Transformed fibroblasts CHMP1A 0.27 0.06 enet 23 0.11 7.0e-09 4.36 6.2 6.5e-10 -0.02 0.65 0.14 FALSE
14 GTEx Cells Transformed fibroblasts RP5-1142A6.9 0.08 0.07 lasso 4 0.06 2.6e-05 -5.36 5.4 7.7e-08 -0.40 0.70 0.23 FALSE
15 GTEx Colon Sigmoid CDK10 0.37 0.12 lasso 8 0.22 2.2e-08 6.46 -7.1 1.7e-12 -0.21 0.01 0.99 FALSE
16 GTEx Esophagus Gastroesophageal Junction CDK10 0.38 0.28 lasso 4 0.29 5.6e-11 6.41 -6.8 7.6e-12 -0.13 0.00 1.00 FALSE
17 GTEx Esophagus Mucosa CDK10 0.36 0.15 lasso 6 0.23 1.9e-15 6.46 -5.7 1.4e-08 -0.18 0.00 1.00 FALSE
18 GTEx Esophagus Muscularis CHMP1A 0.15 0.01 enet 32 0.09 6.6e-06 -2.30 5.7 1.5e-08 -0.11 0.06 0.17 FALSE
19 GTEx Esophagus Muscularis CDK10 0.24 0.11 enet 19 0.14 4.3e-09 6.46 -7.6 3.1e-14 -0.21 0.00 1.00 TRUE
20 GTEx Heart Atrial Appendage CDK10 0.26 0.07 lasso 3 0.13 1.4e-06 -2.92 -5.3 8.7e-08 -0.21 0.01 0.97 FALSE
21 GTEx Lung SPIRE2 0.17 0.01 enet 24 0.04 7.7e-04 4.39 -5.2 2.1e-07 -0.05 0.02 0.97 FALSE
22 GTEx Muscle Skeletal CDK10 0.17 0.12 lasso 6 0.10 9.2e-10 6.46 -6.8 9.2e-12 -0.17 0.00 1.00 FALSE
23 GTEx Nerve Tibial CDK10 0.42 0.28 enet 16 0.35 1.2e-25 1.49 -5.1 2.7e-07 -0.22 0.72 0.28 FALSE
24 GTEx Ovary CDK10 0.45 0.11 lasso 8 0.25 6.8e-07 6.46 -5.7 1.1e-08 -0.19 0.01 0.97 TRUE
25 GTEx Pituitary VPS9D1-AS1 0.21 -0.01 lasso 9 -0.01 5.7e-01 6.46 6.6 4.5e-11 0.15 0.03 0.56 FALSE
26 GTEx Prostate CDK10 0.41 0.16 lasso 6 0.24 1.0e-06 6.46 -5.6 2.3e-08 -0.19 0.00 0.97 FALSE
27 GTEx Skin Not Sun Exposed Suprapubic CHMP1A 0.25 0.01 enet 21 0.08 5.3e-05 4.36 7.4 1.6e-13 0.09 0.10 0.81 FALSE
28 GTEx Skin Sun Exposed Lower leg VPS9D1 0.24 0.13 lasso 6 0.15 3.4e-12 3.49 5.6 2.1e-08 0.07 0.19 0.81 FALSE
29 GTEx Skin Sun Exposed Lower leg CHMP1A 0.36 0.11 enet 29 0.19 1.5e-15 4.36 6.5 9.2e-11 0.09 0.98 0.02 FALSE
30 GTEx Skin Sun Exposed Lower leg CDK10 0.30 0.18 enet 18 0.29 3.0e-24 6.46 -5.6 1.8e-08 -0.19 0.00 1.00 FALSE
31 GTEx Skin Sun Exposed Lower leg VPS9D1-AS1 0.18 0.04 lasso 5 0.06 1.2e-05 4.39 6.4 1.5e-10 0.07 0.01 0.99 FALSE
32 GTEx Small Intestine Terminal Ileum VPS9D1 0.34 0.04 enet 11 0.11 2.4e-03 6.46 6.8 1.3e-11 0.16 0.01 0.93 FALSE
33 GTEx Stomach CDK10 0.35 0.12 enet 12 0.22 6.4e-11 6.41 -5.8 5.0e-09 -0.20 0.00 1.00 TRUE
34 GTEx Testis RP5-1142A6.2 0.21 0.13 lasso 4 0.12 7.2e-06 -6.08 -6.4 1.6e-10 0.60 0.01 0.94 TRUE
35 GTEx Thyroid RPL13 0.13 0.05 enet 10 0.06 1.4e-05 4.28 -5.3 9.9e-08 -0.02 0.98 0.01 TRUE
36 METSIM Adipose CHMP1A 0.27 0.05 lasso 9 0.07 1.3e-10 4.36 7.0 2.6e-12 0.02 0.18 0.80 FALSE
37 METSIM Adipose RP11-368I7.4 0.04 0.03 enet 12 0.02 2.2e-04 6.46 6.1 1.0e-09 0.17 0.00 1.00 FALSE
38 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma CHMP1A 0.07 0.02 blup 38 0.05 3.5e-06 -2.62 5.6 2.4e-08 0.02 0.33 0.24 FALSE
39 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma CHMP1A 0.18 0.01 enet 11 0.06 3.8e-04 4.36 5.4 5.3e-08 0.03 0.06 0.14 FALSE
40 The Cancer Genome Atlas Brain Lower Grade Glioma CHMP1A 0.07 0.03 blup 37 0.03 1.3e-04 4.36 6.6 3.2e-11 0.04 0.12 0.70 FALSE
41 The Cancer Genome Atlas Pheochromocytoma and Paraganglioma CDK10 0.20 0.02 enet 15 0.08 5.3e-04 4.36 -6.0 2.1e-09 -0.08 0.00 0.16 FALSE
42 The Cancer Genome Atlas Prostate Adenocarcinoma DBNDD1 0.25 0.00 blup 65 0.06 1.1e-06 5.49 -5.3 1.4e-07 -0.01 0.01 0.14 FALSE
43 The Cancer Genome Atlas Thyroid Carcinoma CHMP1A 0.11 0.09 blup 38 0.08 5.1e-08 -2.62 5.3 1.0e-07 0.05 0.79 0.16 FALSE
44 The Cancer Genome Atlas Thyroid Carcinoma DBNDD1 0.17 0.00 blup 66 0.04 6.6e-05 -2.63 -5.9 3.7e-09 0.05 0.04 0.11 TRUE