[Hub]/) : Traits : Comparative height size at age 10 : ← →

chr2:46,021,381-47,829,230

Best TWAS P=1.9e-14 · Best GWAS P=7.5e-18 conditioned to 1.38e-11

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
12	GTEx	Skin Not Sun Exposed Suprapubic	PIGF	0.14	0.08	lasso	4	0.07	1.7e-04	7.3	-7.7	1.9e-14	0.28	0.53	0.04	TRUE
9	GTEx	Esophagus Gastroesophageal Junction	AC016722.2	0.30	0.07	lasso	4	0.11	7.7e-05	5.2	-6.5	8.0e-11	0.07	0.25	0.04	FALSE
7	GTEx	Colon Sigmoid	ATP6V1E2	0.25	0.08	enet	17	0.13	3.3e-05	4.6	-6.5	9.2e-11	0.14	0.56	0.19	FALSE
10	GTEx	Heart Left Ventricle	ATP6V1E2	0.38	0.05	enet	32	0.20	1.1e-10	3.6	-6.4	1.5e-10	0.11	0.94	0.00	FALSE
18	The Cancer Genome Atlas	Prostate Adenocarcinoma	ATP6V1E2	0.04	0.02	lasso	3	0.02	4.6e-03	6.5	-6.3	3.5e-10	0.16	0.02	0.97	FALSE
11	GTEx	Pituitary	ATP6V1E2	0.33	0.05	enet	19	0.14	2.6e-04	5.8	-5.7	1.4e-08	0.06	0.20	0.12	FALSE
6	GTEx	Breast Mammary Tissue (Female)	AC016722.4	0.20	0.05	lasso	3	0.05	1.3e-02	-4.1	-5.7	1.5e-08	0.51	0.06	0.36	FALSE
8	GTEx	Esophagus Gastroesophageal Junction	CRIPT	0.21	0.14	enet	9	0.18	6.4e-07	4.4	5.7	1.5e-08	-0.13	0.77	0.02	FALSE
4	GTEx	Brain Nucleus accumbens basal ganglia	CRIPT	0.27	-0.01	enet	8	0.02	1.2e-01	5.1	5.6	2.2e-08	-0.09	0.12	0.06	FALSE
5	GTEx	Brain Nucleus accumbens basal ganglia	ATP6V1E2	0.31	-0.01	enet	28	0.05	2.1e-02	3.5	-5.5	5.1e-08	-0.05	0.12	0.05	FALSE
3	GTEx	Brain Frontal Cortex BA9	ATP6V1E2	0.40	-0.01	enet	35	0.06	1.4e-02	3.6	-5.5	5.2e-08	-0.06	0.11	0.06	FALSE
13	GTEx	Vagina	ATP6V1E2	0.31	0.00	lasso	7	-0.01	6.5e-01	3.6	-5.4	5.4e-08	0.29	0.10	0.06	FALSE
1	GTEx	Adipose Subcutaneous	CRIPT	0.12	0.10	lasso	3	0.09	7.1e-08	4.7	5.4	5.7e-08	-0.05	0.99	0.00	FALSE
17	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	CRIPT	0.13	0.07	enet	13	0.10	7.9e-05	4.5	5.4	5.7e-08	0.00	0.09	0.38	FALSE
15	The Cancer Genome Atlas	Colon Adenocarcinoma	ATP6V1E2	0.11	0.04	blup	75	0.06	2.0e-04	3.7	-5.3	9.2e-08	0.11	0.19	0.72	FALSE
2	GTEx	Adrenal Gland	CRIPT	0.16	0.10	enet	11	0.13	2.3e-05	4.9	5.3	1.4e-07	-0.08	0.69	0.02	FALSE
16	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	CRIPT	0.11	0.11	lasso	3	0.10	1.7e-06	4.9	5.2	2.6e-07	-0.09	0.46	0.52	FALSE
14	GTEx	Whole Blood	CRIPT	0.11	0.04	enet	18	0.05	1.2e-05	4.5	5.1	2.8e-07	-0.09	0.91	0.00	FALSE