[Hub]/) : Traits : Comparative height size at age 10 :

chr3:11,829,474-13,402,150

Best TWAS P=2.02e-12 · Best GWAS P=6.79e-12 conditioned to 0.0119

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Visceral Omentum MKRN2 0.20 0.05 enet 11 0.09 1.7e-05 -6.6 -6.2 5.1e-10 -0.81 0.01 0.98 FALSE
2 GTEx Artery Tibial MKRN2 0.27 0.09 enet 20 0.25 3.1e-19 -2.6 -6.1 8.3e-10 -0.68 0.27 0.73 FALSE
3 GTEx Artery Tibial TSEN2 0.14 0.10 lasso 6 0.07 5.3e-06 -6.0 6.2 7.0e-10 0.82 0.18 0.82 FALSE
4 GTEx Cells EBV-transformed lymphocytes MKRN2 0.32 0.26 lasso 4 0.21 1.5e-07 -5.2 5.3 1.1e-07 0.74 0.57 0.39 FALSE
5 GTEx Esophagus Gastroesophageal Junction MKRN2 0.17 0.10 enet 13 0.07 1.9e-03 -6.6 -7.0 2.0e-12 -0.73 0.04 0.86 TRUE
6 GTEx Esophagus Muscularis MKRN2 0.15 0.05 lasso 8 0.12 8.9e-08 6.4 -6.2 6.8e-10 -0.76 0.02 0.98 FALSE
7 GTEx Heart Atrial Appendage MKRN2 0.14 0.09 lasso 3 0.08 1.5e-04 -6.1 -6.5 6.5e-11 -0.76 0.05 0.94 FALSE
8 GTEx Heart Left Ventricle MKRN2 0.21 0.05 enet 15 0.14 1.1e-07 -6.6 -6.7 2.3e-11 -0.74 0.03 0.97 FALSE
9 GTEx Thyroid MKRN2 0.11 0.04 enet 14 0.05 6.3e-05 -6.5 -5.7 1.5e-08 -0.70 0.06 0.93 FALSE
10 YFS Blood RAF1 0.02 0.03 lasso 2 0.03 2.1e-10 -6.4 -6.5 5.8e-11 -0.77 0.05 0.95 FALSE
11 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma RAF1 0.03 0.02 blup 59 0.02 1.6e-03 -4.5 5.8 4.9e-09 0.61 0.03 0.88 FALSE
12 The Cancer Genome Atlas Testicular Germ Cell Tumors RAF1 0.31 0.16 lasso 4 0.16 3.8e-06 6.7 6.2 4.9e-10 0.74 0.01 0.98 FALSE