[Hub]/) : Traits : Comparative height size at age 10 :

chr3:37,332,662-38,766,338

Best TWAS P=6.76e-10 · Best GWAS P=1.31e-08 conditioned to 0.486

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex PLCD1 0.07 0.02 lasso 4 0.03 4.2e-04 3.5 5.5 4.2e-08 0.73 0.03 0.92 FALSE
2 CommonMind Brain Pre-frontal Cortex VILL 0.26 0.38 lasso 3 0.38 1.9e-49 5.2 -5.4 6.5e-08 -0.99 0.05 0.95 FALSE
3 GTEx Brain Caudate basal ganglia VILL 0.35 0.38 lasso 8 0.33 3.9e-10 5.3 -5.6 2.5e-08 -0.97 0.02 0.98 FALSE
4 GTEx Brain Cortex VILL 0.33 0.29 lasso 2 0.25 1.8e-07 5.5 -5.6 2.0e-08 -0.89 0.02 0.98 FALSE
5 GTEx Brain Frontal Cortex BA9 VILL 0.31 0.30 enet 11 0.34 7.9e-10 5.4 -5.7 1.6e-08 -0.86 0.02 0.98 FALSE
6 GTEx Brain Nucleus accumbens basal ganglia VILL 0.31 0.13 lasso 6 0.12 5.2e-04 5.3 -6.2 6.8e-10 -0.86 0.02 0.93 TRUE
7 ROSMAP Brain Pre-frontal Cortex VILL 0.34 0.46 lasso 3 0.46 3.1e-65 5.2 -5.3 1.3e-07 -0.96 0.06 0.94 FALSE
8 ROSMAP Brain Pre-frontal Cortex PLCD1 0.13 0.12 bslmm 421 0.12 6.6e-15 5.5 -5.6 2.4e-08 -0.80 0.02 0.98 FALSE
9 YFS Blood PLCD1 0.07 0.08 enet 15 0.08 8.0e-25 5.5 5.6 2.5e-08 0.85 0.02 0.98 FALSE
10 The Cancer Genome Atlas Breast Invasive Carcinoma PLCD1 0.01 0.02 blup 55 0.01 7.3e-03 5.2 5.3 8.8e-08 0.88 0.02 0.89 FALSE
11 The Cancer Genome Atlas Brain Lower Grade Glioma VILL 0.03 0.01 blup 52 0.01 1.5e-02 5.4 -5.3 1.1e-07 -0.73 0.01 0.67 FALSE
12 The Cancer Genome Atlas Prostate Adenocarcinoma PLCD1 0.05 0.04 enet 8 0.04 6.3e-05 5.2 5.3 1.2e-07 0.81 0.02 0.98 FALSE