TWAS hub - PLCD1

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.0720	0.0320	2.5e-03	0.021	0.009	0.020	0.013	0.025	1.2e-03	2.7e-02	1.3e-03	7.9e-03	4.2e-04
2	GTEx	Brain Cerebellar Hemisphere	0.3280	0.1160	7.3e-03	-0.009	NA	0.011	NA	-0.007	6.1e-01	NA	1.6e-01	NA	5.4e-01
3	GTEx	Colon Transverse	0.1960	0.0700	3.6e-03	0.078	NA	0.074	NA	0.083	1.5e-04	NA	2.1e-04	NA	9.3e-05
4	GTEx	Skin Not Sun Exposed Suprapubic	0.1080	0.0440	4.0e-03	0.101	NA	0.059	NA	0.067	3.7e-06	NA	3.8e-04	NA	1.5e-04
5	ROSMAP	Brain Pre-frontal Cortex	0.1318	0.0320	8.8e-11	0.115	0.102	0.101	0.118	0.110	1.3e-14	4.7e-13	7.1e-13	6.6e-15	5.0e-14
6	YFS	Blood	0.0689	0.0155	0.0e+00	0.075	0.072	0.080	0.079	0.079	2.0e-23	1.6e-22	8.0e-25	1.1e-24	1.7e-24
7	TCGA	Breast Invasive Carcinoma	0.0127	0.0073	2.0e-03	0.017	0.008	0.005	NA	0.006	1.9e-04	7.3e-03	2.6e-02	NA	1.5e-02
8	TCGA	Prostate Adenocarcinoma	0.0523	0.0240	1.8e-05	0.041	0.037	0.039	NA	0.033	3.9e-05	8.8e-05	6.3e-05	NA	2.0e-04
9	TCGA	Thyroid Carcinoma	0.3540	0.0880	4.4e-07	0.020	0.086	0.092	NA	0.082	3.9e-03	1.1e-08	2.8e-09	NA	2.3e-08

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9
Sitting height	6.8	48.4	107.2	8.3	1.1	-1.4	0.7	-8.7	10.4	9.1	9.7	1.4
Height	4.3	82.7	153.8	10.1	3.3	-0.3	7.6	-11.9	12.4	11.5	12.0	1.7
Medication: Atorvastatin	4.2	5.2	10.0	1.8	-0.4	-0.3	-1.1	-3.0	3.2	3.1	3.0	2.3
Standing height	4.1	40.4	77.8	7.2	3.1	0.1	4.3	-8.4	8.8	8.1	8.3	0.5
Comparative height size at age 10	3.2	17.8	31.1	5.5	2.3	0.2	2.4	-5.6	5.6	5.3	5.3	-0.1
Time employed in main current job	3.1	3.6	7.7	2.8	0.1	0.0	1.1	-2.6	2.0	2.3	1.9	-1.8
Had menopause	2.7	3.3	7.0	1.5	-0.8	-1.0	1.0	-2.4	2.2	2.4	2.6	1.3
Forced vital capacity (FVC), Best measure	2.6	9.5	18.4	3.4	4.3	2.7	2.4	-3.8	2.9	2.7	3.3	1.2
Maternal smoking around birth	2.5	3.6	8.1	2.7	0.7	0.1	0.5	-2.5	2.0	2.8	2.2	0.9
Osteoarthritis (self-reported)	2.5	3.3	8.2	-1.9	-0.2	-0.1	-0.4	2.9	-2.6	-2.2	-2.5	-0.4
Forced expiratory volume in 1-second (FEV1), Best measure	2.4	7.6	11.9	2.8	3.5	3.4	2.4	-3.4	2.2	2.0	2.9	1.8
Reason for reducing amount of alcohol drunk: Health precaution	2.4	2.8	5.4	1.8	1.4	0.2	0.2	-2.3	2.0	2.1	1.9	1.5
Forced expiratory volume in 1-second (FEV1), predicted	2.4	5.0	11.4	3.4	1.0	0.5	1.6	-2.9	2.8	2.3	2.8	0.9
Arm fat-free mass (right)	2.1	10.5	22.0	3.9	2.5	1.3	0.4	-4.7	4.2	4.0	3.9	-0.6
Stomach or abdominal pain in last month	2.0	2.5	6.2	2.5	2.1	0.6	-0.2	-1.9	1.4	1.8	1.2	-1.1
Age at First Birth	1.9	2.8	5.6	-2.0	-1.3	-1.1	-0.7	2.4	-1.7	-1.9	-2.3	-0.2
Falls in the last year	1.9	2.5	6.2	-1.9	0.3	-1.1	-1.0	2.5	-1.9	-1.6	-2.0	-0.6
Bipolar Disorder (2011)	1.8	1.8	5.7	-0.9	-0.9	-1.4	2.4	1.0	-1.3	-1.2	-1.6	-0.2
Lupus	1.8	2.7	7.0	1.8	0.4	-0.4	1.0	-2.3	2.0	2.6	1.7	-0.5
Ever used hormone-replacement therapy (HRT)	1.8	2.3	4.5	1.9	-0.2	0.6	0.1	-1.8	1.9	1.9	2.1	1.3
Forced vital capacity (FVC)	1.8	6.9	13.2	3.1	3.6	1.9	0.8	-3.3	2.8	2.8	2.9	0.2
Arm predicted mass (right)	1.8	9.2	18.8	3.7	2.5	1.3	0.5	-4.3	3.9	3.7	3.6	-0.8
Age at last live birth	1.8	2.7	5.8	-2.3	0.0	0.9	-1.3	2.0	-1.6	-2.4	-1.9	-0.0
Ovarian Cancer	1.7	2.2	8.3	-1.5	-1.9	0.7	1.3	0.9	-1.3	-0.7	-0.8	2.9
Diabetes (mother)	1.7	2.2	5.3	2.0	1.2	1.3	0.9	-2.3	1.4	1.4	1.7	0.3
Medication: Ramipril	1.7	2.1	4.8	1.0	-0.1	-0.4	-0.9	-1.9	1.8	2.2	1.8	-1.5
Eye problems/disorders: None of the above	1.7	1.9	6.3	2.5	1.0	1.0	0.9	-1.8	0.7	1.4	1.0	-1.2
Hand grip strength (right)	1.6	4.4	8.6	2.4	1.0	1.0	-1.6	-2.9	2.9	2.4	2.5	0.3
Relative age voice broke	1.6	2.4	8.1	-2.8	-0.1	0.8	-1.3	1.9	-1.5	-1.8	-1.4	0.3
Trunk fat-free mass	1.6	9.3	18.0	4.0	2.8	1.3	0.8	-4.2	3.9	3.6	3.3	-1.2
Trunk predicted mass	1.6	9.4	17.9	4.0	2.9	1.2	0.8	-4.2	3.9	3.6	3.4	-1.2
Handedness (chirality/laterality): Left-handed	1.6	1.9	3.5	-1.8	-1.1	-1.1	0.8	1.5	-1.9	-1.7	-1.5	0.4
Illnesses of father: High blood pressure	1.6	2.0	5.5	-0.8	0.6	2.0	-2.3	0.8	-1.3	-1.3	-1.1	1.7
Bipolar Disorder or Schizophrenia	1.5	3.7	13.2	-1.1	-1.3	-1.8	3.6	0.5	-1.6	-1.3	-1.8	-2.5
Ever had hysterectomy (womb removed)	1.5	1.6	5.3	2.3	1.5	1.7	-0.9	-1.1	0.9	0.9	0.8	-0.5
Severe depression (siblings)	1.5	1.6	4.9	1.3	1.3	1.0	-2.2	-0.7	1.1	0.7	1.0	1.5
Glaucoma (self-reported)	1.5	1.8	5.7	-1.3	-2.4	-1.0	0.2	0.6	-1.3	-1.4	-1.2	1.4
Pain type(s) experienced in last month: Hip pain	1.5	1.9	5.2	2.3	1.3	1.1	-0.7	-1.1	1.4	1.5	1.2	-1.1
Deep venous thrombosis (DVT) (self-reported)	1.5	2.0	6.9	-1.4	0.9	0.0	0.2	1.4	-1.9	-0.9	-1.5	2.6
Alzheimer’s Disease (in mother)	1.4	1.6	4.8	-0.6	-1.5	-2.2	1.3	1.0	-1.0	-0.6	-1.2	-1.3
Medication for hormone replacement therapy	1.4	1.6	3.2	1.3	-0.5	1.1	1.3	-1.8	1.3	1.3	1.5	-0.6
Forced expiratory volume in 1-second (FEV1)	1.4	4.6	7.8	2.6	2.8	2.5	1.0	-2.6	2.0	1.8	2.2	0.7
Smoking status: Previous	1.4	2.1	8.1	1.4	2.8	1.7	1.6	-1.5	0.6	0.3	1.1	0.3
Whole body fat-free mass	1.4	8.0	16.3	3.6	2.4	1.2	1.3	-4.0	3.5	3.2	3.2	-1.0
Whole body water mass	1.4	7.9	15.8	3.6	2.4	1.2	1.3	-4.0	3.5	3.2	3.1	-1.1
Guilty feelings	1.4	2.2	3.3	-1.5	1.1	0.5	1.5	1.4	-1.8	-1.7	-1.8	-1.4
Arm fat-free mass (left)	1.4	6.9	13.9	3.3	2.5	1.1	0.6	-3.7	3.3	3.1	2.9	-0.6
Supplements: Zinc	1.3	1.4	2.5	-1.4	-0.2	1.3	-0.2	1.3	-1.3	-1.6	-1.4	1.2
Illnesses of siblings	1.3	1.8	7.7	-0.8	-0.7	-2.8	0.4	1.6	-1.2	-1.0	-1.4	0.5
Pulse rate	1.3	2.3	11.3	-1.4	1.6	0.9	3.4	0.1	-1.2	-0.3	-1.0	0.9
Exposure to tobacco smoke outside home	1.3	1.8	4.5	1.4	-1.2	0.1	-2.1	-1.3	1.5	1.3	1.6	0.6
Eye problems/disorders: Cataract	1.3	1.5	5.8	-2.4	0.6	0.5	-1.7	1.0	-0.1	-0.9	-0.1	1.5
Medication: Gliclazide	1.3	1.5	9.5	-0.2	0.6	1.8	0.1	-0.4	0.5	-0.2	-0.1	-3.1
Basal metabolic rate	1.3	7.5	14.8	3.5	2.3	1.1	1.4	-3.9	3.5	3.1	3.1	-0.8
Arm predicted mass (left)	1.3	6.6	12.7	3.4	2.3	0.6	0.2	-3.6	3.3	3.1	2.9	-0.8
Bipolar Disorder (2018)	1.2	1.9	4.4	-1.0	-1.5	-1.8	2.1	1.1	-1.2	-1.2	-1.4	-0.6
Eye problems/disorders: Diabetes related eye disease	1.2	1.3	2.8	0.5	0.3	0.7	-0.9	-1.3	1.7	1.0	1.5	-1.6
Diabetes (father)	1.2	1.5	2.7	-1.2	1.3	1.3	-0.3	1.1	-1.6	-1.6	-1.5	0.1
Supplements: Glucosamine	1.2	1.6	3.2	-1.4	-0.1	1.0	-1.0	1.8	-1.1	-1.6	-1.3	1.2
Medication: Levothyroxine sodium	1.2	2.0	10.0	1.2	0.1	-1.1	3.2	-0.8	0.4	1.1	0.7	1.6
Number of live births	1.2	1.7	3.2	-1.4	-0.5	1.4	0.7	1.8	-1.7	-1.5	-1.4	-0.7
Exposure to tobacco smoke at home	1.2	1.4	2.6	-0.1	-1.3	-0.8	-1.4	1.6	-1.2	-1.5	-1.3	-0.4
Fractured/broken bones in last 5 years	1.2	1.6	2.8	-1.6	1.1	1.2	-1.2	1.4	-0.8	-1.7	-1.3	-0.9
Schizophrenia (2018)	1.1	2.3	8.9	-0.6	-0.4	-0.9	3.0	-0.2	-1.1	-0.7	-1.2	-2.7
Neuroticism (2016)	1.1	1.6	4.2	-1.6	-1.2	-0.1	2.1	1.0	-1.2	-0.8	-1.2	-1.3
Leg fat-free mass (left)	1.1	5.9	12.1	3.0	1.6	1.0	2.1	-3.5	2.9	2.6	2.8	-0.6
Average weekly fortified wine intake	1.1	1.3	3.9	-0.6	-1.7	-1.6	-0.7	0.7	-0.7	-0.4	-0.6	2.0
Tinnitus: Yes, but not now, but have in the past	1.1	1.2	4.8	-0.7	-2.2	-1.0	-1.6	1.1	-0.4	-0.3	-0.4	0.1
Leg predicted mass (left)	1.1	6.1	12.4	3.1	1.6	1.1	2.2	-3.5	3.0	2.6	2.9	-0.7
Nervous feelings	1.1	2.0	4.4	-0.3	0.9	0.8	2.0	1.3	-2.0	-1.2	-2.1	-1.2
Frequency of tenseness / restlessness in last 2 weeks	1.1	1.7	3.0	-1.2	1.2	1.1	-0.5	1.5	-1.3	-1.2	-1.7	-1.6
Number of children fathered	1.1	1.3	2.3	-1.4	-1.3	-0.2	-0.9	1.5	-1.3	-1.0	-1.3	-0.1
Mean time to correctly identify matches	1.1	2.1	4.0	-1.5	-1.8	-0.3	-0.3	2.0	-1.6	-2.0	-1.6	0.1
Heart disease (mother)	1.1	1.4	8.3	0.3	0.3	-0.3	-0.7	-0.5	1.0	1.0	1.1	2.9
Qualifications: NVQ or HND or HNC or equivalent	1.1	1.3	2.9	1.3	1.7	1.0	-0.5	-1.1	1.2	1.3	0.8	0.7
Supplements: Vitamin C	1.1	1.3	5.7	1.2	0.6	1.8	-0.9	-0.3	0.0	0.5	0.1	2.4
Leg fat-free mass (right)	1.1	5.7	12.5	3.0	1.4	1.0	2.3	-3.5	2.8	2.5	2.7	-0.9
Leg predicted mass (right)	1.1	5.9	12.4	3.1	1.5	1.1	2.2	-3.5	2.8	2.5	2.7	-1.0
Mother’s age at death	1.1	1.3	2.5	-1.5	-0.8	-0.1	0.7	1.0	-1.3	-1.4	-1.2	1.6
Eye problems/disorders: Glaucoma	1.1	1.3	2.8	-1.7	-1.6	-0.2	0.3	0.9	-1.4	-1.4	-1.3	0.5
Reaction Time	1.0	2.0	3.8	-1.4	-1.4	-0.1	0.1	2.0	-1.9	-1.9	-1.7	0.0
Type 2 Diabetes (T2D) (2012)	1.0	1.1	4.3	0.2	-2.1	-0.8	1.3	-0.8	0.9	0.8	1.0	0.5
Hair/balding pattern: Pattern 2	1.0	1.3	5.2	-0.7	-1.2	-0.6	2.3	0.7	-1.3	-0.8	-1.1	0.1
Weight	1.0	4.9	9.1	2.6	1.9	0.8	1.7	-3.0	2.8	2.6	2.7	-0.0
Breastfed as a baby	1.0	1.3	2.5	-1.2	0.4	-0.2	-1.2	1.6	-1.3	-1.1	-1.6	-0.9
Blood clot in the leg (DVT)	1.0	1.3	6.4	-0.7	1.1	-0.5	0.4	0.7	-1.3	-0.1	-0.9	2.5
Health satisfaction	1.0	1.3	2.4	-1.4	-0.4	0.7	0.6	1.3	-1.6	-1.4	-1.5	0.3
Mood swings	1.0	1.8	3.2	-1.0	0.8	1.3	1.0	1.1	-1.7	-1.3	-1.5	-1.8
Tinnitus: Yes, now most or all of the time	1.0	1.2	4.6	-0.5	-0.8	-2.2	0.1	1.5	-0.9	-1.0	-0.9	0.2
Basal cell carcinoma (self-reported)	1.0	1.2	2.8	1.7	-0.7	-1.1	1.1	-0.6	1.1	1.3	0.9	0.8
Heart disease (siblings)	1.0	1.3	6.1	0.0	1.7	2.5	-0.4	-0.8	0.6	0.2	0.7	0.8
Depression (Nagel 2018)	0.9	1.3	3.5	-1.9	0.1	-1.7	1.3	1.2	-1.1	-0.5	-1.0	0.5
Major Depression (MDD)	0.9	1.1	5.2	-0.7	-1.2	-0.4	1.1	-0.6	0.7	0.6	0.4	-2.3
Hypothyroidism (self reported)	0.9	2.1	12.4	0.7	1.3	-1.6	3.5	-0.4	0.3	0.3	0.4	1.0
Angina	0.9	1.2	2.6	1.1	0.5	0.6	-0.2	-1.5	1.4	1.3	1.6	-0.1
Age when periods started (menarche)	0.9	2.1	4.9	-1.4	-2.2	-1.2	-1.8	1.5	-0.5	-1.0	-0.8	-1.9
Trunk fat mass	0.9	4.0	7.6	1.8	1.0	-0.2	2.1	-2.4	2.8	2.4	2.6	1.0
Mouth/teeth dental problems	0.9	1.4	5.7	-1.2	1.0	2.4	-1.0	0.9	-1.0	-0.7	-1.0	0.2
Impedance of arm (left)	0.9	3.9	16.6	-0.4	-1.6	-2.3	4.1	-0.5	1.7	1.4	1.9	1.6
Birth weight of first child	0.9	1.6	7.1	0.8	1.4	1.5	-1.5	-0.2	-0.3	-0.3	-0.1	-2.7
Loud music exposure frequency	0.9	1.0	2.8	-0.9	-0.2	-0.2	0.0	1.7	-1.2	-1.6	-1.1	0.3
Number of full brothers	0.9	1.1	3.8	-0.5	1.2	2.0	1.7	0.1	-0.7	-0.7	-0.5	-0.4
Angina (self-reported)	0.9	1.2	2.3	1.3	0.4	0.8	-0.0	-1.4	1.4	1.3	1.5	-0.3
Pulse rate, automated reading	0.9	2.8	20.9	-0.3	0.8	-0.2	4.6	-0.5	-1.4	0.0	-0.9	0.9
Chest pain or discomfort	0.9	1.4	6.9	0.0	-1.2	-2.6	-1.0	0.6	-0.2	0.1	-0.3	1.5
Mouth/teeth dental problems: Mouth ulcers	0.9	1.5	6.3	0.8	-0.5	-0.3	2.5	-0.0	-0.4	-0.3	-0.4	-2.3
Back pain experienced in last month	0.9	1.3	4.0	2.0	1.8	0.6	0.3	-0.8	0.8	1.2	0.6	-0.8
Mineral and other dietary supplements	0.9	1.2	3.5	0.5	-0.2	0.1	1.9	-1.3	1.2	1.0	1.4	-1.0
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.9	1.9	8.4	-0.6	1.0	2.9	-1.2	0.5	-1.0	-0.5	-0.3	2.0
Commuting to job workplace: Public transport	0.9	1.1	2.8	-0.1	-1.3	-1.7	0.2	1.2	-0.4	-0.9	-1.2	-1.0
Alcohol drinker status: Never	0.9	1.1	3.9	0.4	-0.3	1.0	0.0	-1.1	1.1	1.1	1.2	-2.0
Average weekly beer plus cider intake	0.9	1.3	2.4	1.1	0.2	-1.0	-1.5	-1.3	1.0	1.4	1.1	-1.0
Myopia	0.9	1.3	2.3	-0.8	-1.5	-1.1	1.1	1.0	-1.2	-1.3	-1.3	-0.5
Coronary Artery Disease (CAD)	0.8	0.9	2.6	-1.0	1.1	-1.2	-1.3	0.4	0.4	-0.2	-0.1	-1.6
Primary Biliary Cirrhosis	0.8	1.2	2.6	1.1	-0.6	-1.6	0.3	-1.3	1.1	1.3	1.3	-0.5
Schizophrenia (2014)	0.8	1.7	5.5	-0.2	0.1	-0.6	2.4	0.0	-1.2	-1.0	-1.3	-2.3
Taking other prescription medications	0.8	1.3	6.6	-1.3	0.2	-0.2	0.4	1.4	-0.7	-0.3	-0.8	2.6
Medication: Atenolol	0.8	0.9	3.2	-1.2	-0.1	0.2	-1.8	0.4	0.5	-0.1	-0.1	-1.8
Number of incorrect matches in round	0.8	1.3	3.1	1.8	0.7	1.2	0.1	-1.4	1.4	0.9	1.2	-0.1
Hearing difficulty/problems with background noise	0.8	1.2	2.4	-0.6	-0.7	1.6	-1.2	1.1	-0.9	-1.2	-1.2	-1.1
Heart attack	0.8	1.0	1.9	-1.3	-0.0	0.4	-1.4	1.1	-0.8	-0.6	-1.0	-1.3
Serious illness, injury or assault of a close relative in last 2 years	0.8	0.9	3.0	-0.2	1.7	1.1	0.7	1.1	-0.7	-1.0	-0.9	0.2
Prospective memory result	0.8	1.0	4.0	0.9	2.0	1.2	-0.2	-0.7	-0.1	0.9	0.7	1.1
Shortness of breath walking on level ground	0.8	1.0	2.6	0.6	0.6	0.1	0.2	-1.2	1.4	1.6	1.4	0.3
Mouth/teeth dental problems: Loose teeth	0.8	1.0	4.0	1.1	0.1	0.1	-0.7	-0.8	1.1	0.2	1.1	2.0
Neck or shoulder pain in last month	0.8	1.1	6.6	0.1	0.7	0.4	-0.8	1.0	-0.2	-0.6	-0.7	-2.6
Medication: Seretide 50 evohaler	0.8	1.0	2.2	0.0	0.2	0.4	-0.7	-0.9	1.2	1.5	1.2	1.5
Unable to work because of sickness or disability	0.8	1.0	2.6	0.8	-0.7	-0.6	-0.8	-1.2	1.4	0.9	1.6	0.7
Depressed Affect (Nagel 2018)	0.7	1.5	4.9	-2.2	0.4	0.1	0.5	1.5	-1.5	-1.1	-1.5	-0.8
Fasting Glucose	0.7	0.8	1.7	1.0	-1.3	0.9	-0.8	-1.3	0.6	0.7	0.8	0.3
Blood Red Count	0.7	6.8	12.0	3.5	2.5	2.0	0.2	-3.0	3.0	3.4	3.1	0.0
Blood White Count	0.7	5.2	10.9	2.4	0.6	0.5	0.1	-3.0	3.3	3.3	2.8	1.3
Waist Hip Ratio (WHR)	0.7	3.0	11.9	0.7	2.7	2.4	3.5	-0.8	-0.7	-0.4	-0.2	-0.3
Systolic Blood Pressure	0.7	3.4	7.8	1.4	-0.4	1.6	-1.0	-2.5	2.8	1.8	2.6	-0.8
Allergy or Eczema	0.7	1.9	3.0	1.6	1.4	0.2	-1.4	-1.4	1.7	1.7	1.4	0.9
Current tobacco smoking	0.7	1.2	3.9	0.3	-1.6	-2.0	-1.5	0.0	0.8	0.8	0.2	-0.4
Bilateral oophorectomy (both ovaries removed)	0.7	0.8	2.3	0.0	-0.2	0.5	-0.1	-1.3	1.5	0.8	1.4	-0.5
Past tobacco smoking	0.7	1.3	6.9	-1.1	-2.6	-1.1	-0.8	0.9	-0.4	0.2	-0.5	0.6
Impedance of arm (right)	0.7	3.2	14.9	-0.6	-1.6	-2.7	3.9	0.4	0.8	0.6	0.8	1.5
Medication: Ibuprofen (e.g. Nurofen)	0.7	0.9	3.3	-0.4	-1.4	-1.8	0.2	1.0	-0.1	-0.5	-0.5	-1.0
Number of full sisters	0.7	0.9	2.8	-0.4	-1.2	-0.6	-1.7	1.2	-0.6	-1.0	-0.7	0.0
Illness, injury, bereavement, stress in last 2 years	0.7	0.8	2.2	-0.4	-1.5	-1.1	-0.0	-0.3	0.6	0.6	0.9	1.4
Hypertension (Self-reported)	0.7	1.9	4.0	0.5	0.4	0.9	0.1	-1.8	2.0	1.9	1.9	-1.3
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.7	0.8	4.1	-2.0	-0.5	0.8	0.8	0.3	-0.8	-0.5	-0.4	0.7
Illnesses of father: Heart disease	0.7	0.9	3.3	-0.5	1.8	0.7	-0.8	0.6	-1.2	-0.3	-1.0	0.7
Qualifications: nursing, teaching	0.7	1.0	3.7	0.1	0.2	-0.5	-1.9	1.4	-1.1	-0.6	-1.2	0.5
Medication for cholesterol	0.7	1.1	2.5	-0.8	-0.8	-1.6	-0.7	1.2	-1.0	-1.3	-1.2	0.2
Smoking status: Current	0.7	1.2	3.3	0.5	-1.4	-1.7	-1.8	0.1	0.7	0.7	-0.0	-1.1
Miserableness	0.7	1.1	2.4	-1.5	-0.3	-0.3	0.2	1.4	-1.5	-1.1	-1.4	-0.3
Ever taken oral contraceptive pill	0.7	0.8	2.3	1.5	0.5	-0.0	0.2	-1.3	1.0	0.8	0.9	0.5
Medication: Bendroflumethiazide	0.7	1.0	4.0	-0.8	1.6	1.2	-0.2	0.5	-0.3	-0.5	-0.3	-2.0
Commuting to job workplace: Cycle	0.7	0.8	2.3	0.3	0.1	-0.7	-0.4	-1.1	1.5	1.0	1.4	-0.1
Pain experienced in last month	0.7	1.1	4.7	-0.3	-1.3	-0.9	-0.3	-0.8	0.7	0.7	1.1	2.2
Heart attack/myocardial infarction (self-reported)	0.7	0.9	2.5	-1.1	0.3	0.5	-1.2	0.9	-0.7	-0.4	-0.9	-1.6
Worry (Nagel 2018)	0.6	1.2	4.4	0.7	1.4	-0.1	2.1	-1.0	0.7	1.0	0.4	-1.1
Alzheimer’s Disease (including proxy)	0.6	0.9	4.6	1.2	-1.2	-2.2	0.4	-0.0	0.4	0.7	-0.0	-0.2
Prostate Cancer	0.6	0.8	1.9	-1.4	-1.2	-0.4	0.3	1.2	-0.8	-1.0	-0.8	-0.3
Crohns Disease (2012)	0.6	0.9	2.3	1.2	-0.8	0.2	-0.4	-0.9	1.4	1.0	1.5	0.2
Triglycerides	0.6	1.0	2.9	-0.8	-1.7	-0.5	0.5	1.1	-1.1	-0.8	-1.2	-0.8
Heel T-Score	0.6	4.9	16.5	1.9	3.3	4.1	1.2	-2.5	1.3	1.2	1.3	-0.2
Medication: Co-codamol	0.6	0.7	4.7	-0.5	-0.3	-0.1	2.2	0.6	-0.5	-0.3	-0.5	0.1
Qualifications: CSEs or equivalent	0.6	0.8	2.1	-0.8	0.5	1.4	0.8	0.6	-0.8	-1.0	-0.8	-0.9
Pain all over the body in last month	0.6	0.6	3.2	-0.2	0.5	1.8	0.6	0.4	-0.5	-1.1	-0.6	0.2
Medication: Simvastatin	0.6	0.9	4.3	-1.0	0.1	1.2	-2.1	0.9	-0.3	-0.5	-0.2	-0.1
Illnesses of mother	0.6	0.7	2.9	0.1	-0.8	-0.9	0.0	0.5	-1.0	-0.3	-0.9	-1.7
Pulse wave reflection index	0.6	0.7	2.5	-0.1	-0.7	-1.6	-0.8	-0.1	1.3	0.3	1.0	0.2
Medication for cholesterol, blood pressure or diabetes	0.6	1.0	2.7	-0.2	0.1	-0.2	0.6	1.6	-1.3	-1.4	-1.4	-0.6
Hypothyroidism/myxoedema (self-reported)	0.6	1.2	6.9	1.2	0.8	-1.2	2.6	-0.4	0.2	0.5	0.4	0.2
High blood pressure (siblings)	0.6	0.8	4.2	0.0	0.5	2.1	-0.3	-0.5	0.5	0.6	0.7	1.1
Pulse wave peak to peak time	0.6	0.7	1.7	1.3	-0.7	0.2	0.4	-1.0	0.6	1.0	0.4	-1.2
Emphysema/chronic bronchitis	0.6	0.7	2.0	-0.7	-1.4	-0.7	-0.6	0.6	-0.3	-0.5	-0.4	-1.4
Migraine (self-reported)	0.6	0.8	1.5	-0.7	-1.1	-0.8	1.2	0.6	-0.8	-1.0	-0.8	0.7
Medication: Ibuprofen	0.6	0.8	3.7	0.1	-1.1	-1.9	-1.0	0.6	0.7	-0.0	0.2	0.1
Whole body fat mass	0.6	2.3	4.0	1.6	1.3	0.2	1.5	-1.8	2.0	1.8	1.9	0.7
Ever had bowel cancer screening	0.6	0.7	2.4	0.2	0.2	1.4	-1.5	0.8	-0.6	-0.4	-0.5	0.7
Osteoporosis (self-reported)	0.6	0.7	1.6	0.8	-0.6	-0.7	-0.3	-0.8	1.3	1.3	1.0	0.4
Ever depressed for a whole week	0.6	0.8	3.6	0.1	-1.9	-0.8	1.2	-0.8	0.6	0.1	0.3	-0.5
Impedance of whole body	0.6	3.1	6.5	-0.2	-1.1	-2.1	2.5	-0.6	2.1	1.7	2.0	2.0
Ulcerative Colitis (UC)	0.5	0.9	2.2	-0.7	-0.3	-0.9	0.7	1.1	-1.5	-0.8	-1.4	0.4
HDL Cholesterol	0.5	0.9	4.5	-0.6	0.6	-1.0	-1.1	0.2	0.3	0.0	0.4	2.1
Ulcerative Colitis	0.5	0.8	2.1	-0.6	0.5	0.3	1.2	0.5	-1.0	-0.4	-1.0	1.4
Lung FEV1/FVC ratio	0.5	2.4	7.7	0.4	-0.4	2.4	1.6	-1.7	0.6	0.7	1.4	2.8
Lung FVC	0.5	2.8	10.8	1.1	3.3	2.8	-1.7	0.0	-0.8	-0.5	-0.3	-1.1
Neuroticism	0.5	1.1	2.1	-0.9	1.1	0.1	1.3	1.0	-1.3	-0.9	-1.4	-0.8
Average weekly spirits intake	0.5	0.6	1.7	1.3	0.9	1.0	0.5	-0.7	0.6	0.4	0.4	0.3
Systolic blood pressure, automated reading	0.5	1.5	3.1	1.6	-0.1	1.1	-0.1	-1.8	1.2	1.3	1.6	-1.1
Trunk fat percentage	0.5	2.0	5.0	0.5	-0.0	-0.8	2.2	-1.2	1.8	1.5	1.8	1.4
Frequency of unenthusiasm / disinterest in last 2 weeks	0.5	0.7	2.2	-1.0	-0.8	-1.5	-0.1	1.0	-0.6	-0.3	-0.9	0.5
High blood pressure	0.5	1.5	3.2	0.5	0.3	0.8	-0.1	-1.6	1.8	1.7	1.7	-1.0
High blood pressure (mother)	0.5	0.7	2.8	-0.3	1.3	1.7	0.2	-0.7	0.7	0.1	0.6	0.7
Qualifications: None of the above	0.5	1.1	3.7	0.6	-0.1	0.2	1.9	-1.1	0.3	1.2	1.0	-1.6
Father’s age at death	0.5	0.7	1.6	0.6	-1.0	0.5	-0.5	-0.7	1.3	0.5	1.1	0.8
Noisy workplace	0.5	0.6	3.3	-0.9	-0.3	0.6	-0.4	0.1	-0.0	-0.3	0.1	-1.8
Qualifications: A levels/AS levels or equivalent	0.5	1.1	3.1	-0.8	-0.1	-1.8	-1.2	1.0	-1.1	-0.8	-1.3	0.1
Depression (self-reported)	0.5	0.6	1.8	-0.5	-0.8	0.4	-1.4	1.1	-0.2	-0.9	-0.4	0.5
Length of working week for main job	0.5	0.5	1.6	1.3	-0.3	0.1	0.4	-0.4	0.7	0.5	0.8	-1.0
Tense / ‘highly strung’	0.5	0.9	2.5	1.6	-0.0	0.3	1.0	-1.3	0.7	1.4	0.6	0.2
Seen doctor (GP) for nerves, anxiety, tension or depression	0.5	0.7	2.4	-0.3	-0.3	0.7	1.5	0.6	-1.0	-0.7	-0.9	0.8
Mouth/teeth dental problems: Bleeding gums	0.5	0.6	1.6	1.0	-0.2	-1.3	0.4	-0.7	0.5	0.2	0.4	-1.3
Gout (self-reported)	0.5	0.6	2.4	0.2	-0.3	1.6	1.5	0.0	-0.9	-0.2	-0.4	-0.1
Medication: Blood pressure	0.5	0.9	2.3	0.1	0.3	-0.5	-0.7	-1.4	1.3	1.5	1.3	0.2
Medication: Allopurinol	0.5	0.7	3.0	0.4	-0.2	1.7	1.2	-0.5	-0.3	-0.0	-0.1	-1.0
Suffer from ‘nerves’	0.5	0.9	1.7	-0.6	0.8	-0.2	1.2	1.1	-1.3	-1.0	-1.1	-0.4
Family relationship satisfaction	0.5	0.6	1.3	-0.3	-0.5	0.7	0.2	0.7	-0.7	-0.9	-1.0	-1.2
Ever had stillbirth, spontaneous miscarriage or termination	0.5	0.5	2.1	1.3	0.5	0.3	-0.0	-0.0	0.0	-0.2	-0.4	-1.5
Breast cancer (self-reported)	0.5	0.6	2.2	-1.5	1.1	-0.6	-0.8	0.5	-0.5	-0.2	-0.4	-0.0
Illnesses of father: None of the above (group 1)	0.5	0.6	3.7	0.1	-0.7	-0.0	0.4	-0.0	0.5	-0.2	0.5	-1.9
Wears glasses or contact lenses	0.5	0.6	2.7	0.9	0.8	0.4	-0.0	-0.6	0.7	0.6	0.5	-1.6
Medication: Blood pressure	0.5	0.9	5.6	-0.5	1.0	2.4	-0.2	0.2	0.3	-0.1	0.3	-0.9
Supplements: Fish oil (including cod liver oil)	0.5	0.7	3.1	-0.2	0.2	0.3	-1.8	0.9	-0.8	-0.7	-1.0	0.4
Diastolic blood pressure, automated reading	0.5	1.5	4.4	-0.5	0.7	0.9	1.8	0.5	-1.5	-0.8	-1.0	-2.1
Vascular/heart problems diagnosed by doctor	0.5	1.4	2.9	-0.5	-0.4	-0.8	0.7	1.4	-1.7	-1.6	-1.6	1.1
Neuroticism (Nagel 2018)	0.4	0.9	1.9	-0.9	0.8	-0.2	1.2	0.8	-0.8	-0.6	-1.0	-1.4
Breast Cancer	0.4	1.1	3.4	1.0	-1.4	-1.4	1.8	-0.5	0.3	0.6	0.4	0.6
Body Mass Index (BMI) (2010)	0.4	0.6	1.6	1.1	-0.4	1.1	-1.3	0.1	-0.3	-0.7	-0.5	-0.4
Mean Putamen Volume	0.4	0.4	1.1	1.0	0.3	-0.8	1.1	-0.3	0.2	0.7	0.6	-0.1
HbA1C	0.4	0.5	0.8	-0.9	-0.9	-0.7	-0.7	0.8	-0.4	-0.7	-0.5	0.4
LDL Cholesterol	0.4	0.7	2.3	0.4	1.5	0.9	-0.6	-0.8	0.5	0.9	0.5	-0.7
Smoking Status	0.4	0.9	2.5	0.7	1.6	0.4	0.3	-1.2	0.9	0.9	0.8	-1.1
Chronotype (morning person)	0.4	0.8	5.5	0.9	-0.1	0.1	0.1	-0.3	0.5	0.6	0.7	-2.3
Hand grip strength (left)	0.4	1.2	3.3	0.6	-0.0	0.7	-1.8	-1.4	1.6	1.0	0.9	-0.3
Vitamin and mineral supplements	0.4	0.5	2.0	-0.9	0.5	-0.6	0.1	-0.4	0.6	0.2	0.6	-1.4
Serious illness, injury or assault to yourself	0.4	0.5	1.2	0.2	0.4	0.2	-0.3	-0.7	1.1	0.7	0.9	-1.1
Had other major operations	0.4	0.5	1.0	-0.1	1.0	-0.9	-0.8	0.8	-0.7	-0.1	-0.8	-0.2
Financial difficulties in last 2 years	0.4	0.5	2.6	0.1	0.7	1.0	-1.6	0.1	-0.5	-0.3	-0.4	-0.6
Hayfever/allergic rhinitis (self-reported)	0.4	0.5	1.6	1.3	0.6	-0.1	0.3	-0.6	0.8	0.9	0.9	0.1
Neuroticism score	0.4	0.8	2.8	-0.5	0.9	-0.3	1.7	0.7	-1.1	-0.6	-1.1	-0.5
Worrier / anxious feelings	0.4	0.8	3.5	-0.5	1.0	-0.0	0.6	0.7	-0.4	-0.5	-0.9	-1.9
Happiness	0.4	0.5	1.2	-0.3	0.8	0.6	-0.3	0.7	-1.1	-0.8	-0.9	-0.5
Medication: Cholesterol lowering	0.4	0.6	1.8	-0.6	-0.6	1.0	-1.4	-0.5	0.7	0.4	0.6	0.5
Medication: Lansoprazole	0.4	0.5	1.2	-1.0	-0.1	1.0	0.3	-0.6	0.4	0.6	0.6	1.1
Peak expiratory flow (PEF)	0.4	0.9	3.0	1.6	1.7	1.3	0.4	-0.6	0.4	0.2	0.5	-0.0
Qualifications: O levels/GCSEs or equivalent	0.4	0.7	3.2	-0.8	-0.1	-1.3	-0.5	0.1	0.4	0.1	0.2	1.8
Medication: Paracetamol	0.4	0.7	1.2	-0.4	0.8	1.0	1.1	0.6	-1.1	-1.1	-0.8	-0.1
Medication: Amlodipine	0.4	0.6	1.3	0.1	-0.6	0.7	0.2	-1.1	0.7	0.9	1.1	0.8
Seen a psychiatrist for nerves, anxiety, tension or depression	0.4	0.5	3.7	-0.1	-0.1	0.6	1.9	-0.0	-0.0	-0.2	-0.3	0.3
Medication: Omeprazole	0.4	0.5	1.5	-0.4	0.4	0.4	-0.9	1.2	-0.7	-0.5	-0.9	-0.3
Overall health rating	0.4	0.8	1.7	1.2	0.7	-1.0	0.8	-0.8	0.6	1.3	0.6	-0.6
Leg pain on walking	0.4	0.6	2.8	0.1	1.7	0.9	-0.0	0.1	-0.2	-0.2	-0.4	-1.1
Average weekly red wine intake	0.4	0.6	2.5	1.6	0.9	0.6	-1.0	-0.3	0.5	-0.1	0.1	-0.0
Friendships satisfaction	0.4	0.5	1.3	0.0	-1.1	-0.9	0.3	0.6	-0.9	-0.3	-0.8	0.2
Commuting to job workplace: Walk	0.4	0.5	2.5	-0.4	0.4	0.6	1.6	0.7	-0.6	-0.3	-0.5	0.2
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.4	0.4	1.5	0.7	-0.5	-0.2	-0.5	-0.5	0.7	1.2	0.7	0.2
Average weekly champagne plus white wine intake	0.4	0.5	2.8	0.3	-0.6	-1.0	-0.2	-0.1	0.4	-0.1	-0.2	-1.7
Ever had prostate specific antigen (PSA) test	0.4	0.4	2.6	0.2	-0.6	0.1	-0.7	0.5	-0.1	0.3	-0.2	1.6
Alcohol drinker status: Previous	0.4	0.4	1.1	0.5	0.8	0.9	1.0	-0.1	0.0	0.0	-0.1	-1.1
Intelligence (Savage-Jansen 2018)	0.3	0.9	4.2	0.6	-0.9	-0.6	0.5	0.7	-0.8	-0.3	-0.9	2.0
BMI	0.3	1.5	4.0	-0.4	2.0	1.6	-0.7	0.5	-1.4	-1.4	-1.3	-0.5
Type 2 Diabetes (T2D) (2018)	0.3	0.6	1.7	0.9	0.8	0.7	-0.8	-0.3	1.3	0.5	1.1	0.3
Sensitivity / hurt feelings	0.3	0.5	2.0	0.8	1.3	-0.2	0.6	-0.3	0.1	0.1	0.1	-1.4
Other serious medical condition/disability diagnosed by doctor	0.3	0.4	1.4	0.6	-1.1	-1.2	0.8	-0.2	0.2	0.2	0.2	0.1
Pack years adult smoking proportion	0.3	0.5	1.2	-0.2	-0.8	-0.5	-1.1	0.6	-0.7	-1.0	-0.7	0.2
Impedance of leg (right)	0.3	1.4	3.5	0.3	0.3	-1.4	-0.1	-0.3	1.9	1.6	1.5	1.6
Townsend deprivation index at recruitment	0.3	0.5	1.9	0.3	-0.8	-1.4	0.0	0.2	0.2	-0.1	-0.4	-1.2
Heel bone mineral density (BMD) T-score, automated (left)	0.3	0.7	4.6	0.6	0.2	2.1	0.3	-0.9	0.6	0.1	0.6	-0.1
Waist circumference	0.3	1.3	2.9	0.8	1.7	1.3	1.1	-1.3	0.9	0.9	1.1	0.6
Ever unenthusiastic/disinterested for a whole week	0.3	0.4	1.0	-0.2	-0.6	-0.3	1.0	-0.8	0.7	0.1	0.6	0.6
Arm fat percentage (right)	0.3	1.1	2.3	-1.2	-0.2	-0.5	1.5	1.3	-1.1	-1.2	-1.0	0.6
Hip circumference	0.3	1.4	3.6	1.0	0.6	-0.3	0.6	-1.3	1.9	1.5	1.6	0.8
Alcohol intake versus 10 years previously	0.3	0.5	1.3	-0.8	-0.1	1.2	-0.8	0.5	-0.6	-1.0	-0.6	-0.4
Frequency of tiredness / lethargy in last 2 weeks	0.3	0.4	1.2	0.3	0.6	-0.8	-0.7	0.3	0.6	0.6	-0.2	-1.1
Mouth/teeth dental problems: Dentures	0.3	0.6	1.8	0.1	-0.5	-1.3	0.8	-0.3	0.6	0.6	0.7	1.1
Asthma	0.3	0.6	1.7	0.3	0.1	0.1	0.2	-1.0	0.6	1.3	0.9	1.1
Pulse wave Arterial Stiffness index	0.3	0.4	1.8	-0.7	1.0	-0.3	-0.1	0.2	0.1	-0.2	0.2	1.3
Headache pain in last month	0.3	0.5	4.2	0.2	0.0	-2.1	0.2	0.6	0.0	0.0	-0.4	0.2
Medication: Ventolin 100micrograms inhaler	0.3	0.4	1.3	0.0	1.2	0.3	-0.4	0.9	-0.8	-0.1	-0.6	-0.1
Birth weight	0.3	0.6	1.9	1.2	0.4	0.8	1.4	-0.9	-0.2	0.4	0.0	-0.6
Chronic bronchitis/emphysema (mother)	0.3	0.4	1.2	-0.9	-0.4	1.1	0.7	0.4	-0.4	-0.5	-0.4	-0.1
Comparative body size at age 10	0.3	0.8	4.8	-0.3	0.1	-1.2	-0.6	-0.4	0.3	-0.1	0.4	2.2
Worry too long after embarrassment	0.3	0.5	1.9	-0.3	0.1	-1.4	0.0	0.7	-0.8	-0.8	-1.0	0.1
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.3	0.3	1.0	-0.0	-0.3	-1.0	-0.8	-0.0	0.6	0.6	0.5	-0.4
Alcohol intake frequency.	0.3	0.7	3.7	-0.3	-1.2	0.7	0.1	0.4	0.1	-0.2	0.2	-1.9
Had major operations	0.3	0.4	1.2	-1.0	-1.1	0.4	-0.7	0.1	0.1	-0.1	0.3	-0.3
Commuting to job workplace: Car/motor vehicle	0.3	0.4	0.8	-0.2	0.7	0.8	-0.1	-0.9	0.4	0.6	0.9	0.0
Loneliness, isolation	0.3	0.4	0.9	-0.5	-0.5	-0.4	-0.3	0.9	-0.8	-0.3	-0.7	0.6
Asthma (self-reported)	0.3	0.6	1.8	0.5	-0.1	0.3	-0.0	-1.0	0.6	1.4	0.9	1.0
High cholesterol (Self-reported)	0.3	0.5	0.8	-0.9	-0.8	-0.3	-0.9	0.7	-0.9	-0.2	-0.6	0.5
Medication: Paracetamol	0.3	0.5	1.3	-0.1	1.1	1.0	0.7	0.6	-0.6	-0.8	-0.5	0.3
Ever smoked	0.3	0.5	3.3	0.3	1.8	-0.2	-0.1	-0.1	0.2	-0.4	0.0	-1.0
Medication: Omeprazole (e.g. Zanprol)	0.3	0.4	1.1	-0.1	0.5	0.5	-1.0	0.8	-0.7	-0.4	-0.6	-0.2
Supplements: Calcium	0.3	0.3	1.1	0.1	-0.8	-0.8	-1.1	0.1	-0.3	0.2	-0.4	-0.1
Schizophrenia vs Biploar Disorder	0.2	0.3	0.9	0.9	0.5	1.0	0.4	-0.4	0.4	-0.1	0.3	-0.0
Irritable Bowel Disease (IBD)	0.2	0.5	1.2	-0.6	-0.1	-0.6	0.2	1.0	-1.1	-0.8	-1.1	-0.2
Verbal and Numeric Reasoning (VNR)	0.2	0.4	1.6	-0.2	-0.4	-1.3	-0.1	0.8	-0.6	-0.4	-0.9	0.4
Blood Eosinophil Count	0.2	1.5	7.4	-1.2	-0.6	-1.6	1.2	-0.2	0.0	0.4	0.0	2.7
Cardiovascular Disease	0.2	0.8	1.3	-0.1	0.6	1.2	0.2	-1.1	1.0	1.1	1.1	-0.7
Respiratory disease	0.2	0.6	2.3	0.2	-0.4	-0.5	-0.4	-0.5	0.4	1.0	0.8	1.5
Number of treatments/medications taken	0.2	0.4	1.5	-0.4	1.0	0.4	1.2	0.1	-0.1	0.1	-0.1	0.6
Frequency of depressed mood in last 2 weeks	0.2	0.3	1.7	-0.7	0.3	-0.6	1.3	0.2	-0.1	0.3	-0.0	0.3
Hearing difficulty/problems: Yes	0.2	0.4	2.0	0.1	-1.4	-0.4	0.1	0.6	-0.2	-0.1	-0.3	-0.8
Relative age of first facial hair	0.2	0.4	0.9	-1.0	-0.1	-0.2	0.7	0.5	-0.9	-0.6	-0.6	-0.6
Hayfever, allergic rhinitis or eczema	0.2	0.5	2.3	0.8	1.0	0.5	-1.5	-0.1	0.3	0.4	-0.2	0.0
Diverticular disease/diverticulitis (self-reported)	0.2	0.3	0.6	-0.2	-0.5	0.5	-0.3	-0.3	0.8	0.8	0.7	0.1
Chronic bronchitis/emphysema (father)	0.2	0.2	0.8	0.0	-0.5	-0.9	-0.1	0.5	-0.1	0.1	-0.1	0.9
Body mass index (BMI)	0.2	0.8	1.7	-0.9	0.6	0.9	-0.2	0.9	-1.3	-1.1	-1.1	-0.1
Impedance of leg (left)	0.2	1.1	2.8	0.1	0.1	-1.4	0.1	-0.2	1.7	1.3	1.2	1.4
Alcohol usually taken with meals	0.2	0.3	0.9	-0.1	0.9	0.8	-0.1	-0.3	0.4	-0.1	0.2	-0.8
Heel bone mineral density (BMD) T-score, automated (right)	0.2	0.5	2.9	0.6	0.3	1.7	-0.2	-0.5	0.5	0.2	0.2	0.2
Diabetes (self-reported)	0.2	0.3	0.7	0.4	0.3	0.2	-0.7	-0.4	0.9	0.4	0.7	-0.4
Hair/balding pattern: Pattern 3	0.2	0.2	1.4	0.1	-0.0	1.2	-0.2	0.2	-0.4	-0.5	-0.4	-0.1
Lung cancer (father)	0.2	0.2	1.3	1.1	-0.1	0.5	0.5	-0.2	0.2	0.2	0.2	-0.2
Hair/balding pattern: Pattern 4	0.2	0.4	1.7	-0.9	-1.3	0.2	0.6	0.5	-0.2	0.1	-0.0	-0.3
Ever highly irritable/argumentative for 2 days	0.2	0.2	1.4	0.3	-0.7	0.3	1.2	0.1	0.3	-0.2	0.2	-0.0
Body fat percentage	0.2	0.8	2.2	0.3	0.3	-0.4	1.5	-0.5	0.9	0.8	1.0	1.3
Age at first live birth	0.2	0.4	1.5	-1.2	-0.1	-0.5	-0.6	0.5	0.0	-1.1	-0.5	-0.5
Medication for pain relief, constipation, heartburn	0.2	0.4	1.4	-0.1	-0.5	-0.2	-0.8	-0.5	0.5	0.2	0.6	1.2
Leg fat mass (right)	0.2	1.0	2.9	1.1	1.7	0.9	0.5	-0.9	0.9	0.7	0.9	0.6
Medication: Aspirin	0.2	0.3	1.2	-0.1	0.2	0.7	-1.1	0.1	0.4	0.3	0.1	-0.7
Knee pain experienced in last month	0.2	0.3	0.9	0.7	0.7	0.2	-0.7	0.2	-0.5	0.3	-0.4	-0.9
Illnesses of siblings: Diabetes	0.2	0.3	0.8	0.1	-0.7	0.6	0.2	-0.9	0.5	0.5	0.7	0.2
Arm fat percentage (left)	0.2	0.7	2.6	-1.1	-0.1	-0.0	1.6	0.9	-0.7	-0.9	-0.5	0.6
Long-standing illness, disability or infirmity	0.2	0.2	0.7	-0.1	0.3	-0.6	0.7	-0.2	0.3	0.5	0.3	0.9
Diabetes diagnosed by doctor	0.2	0.4	1.4	0.6	0.2	-0.0	-0.2	-0.5	1.2	0.6	1.0	-0.4
Medication: Aspirin	0.2	0.2	0.8	0.1	-0.1	0.2	-0.9	0.2	0.6	0.5	0.2	-0.7
Number of self-reported non-cancer illnesses	0.2	0.3	1.3	-0.3	1.1	0.7	0.2	0.3	-0.1	0.2	0.1	0.7
Hearing aid user	0.2	0.2	0.6	0.0	0.8	0.2	-0.8	0.1	0.1	0.5	0.3	0.4
Financial situation satisfaction	0.2	0.3	1.5	-0.4	-0.5	-0.3	-0.2	0.4	-0.6	-0.3	-0.2	1.2
Medication: Lisinopril	0.2	0.3	1.1	-1.1	0.4	-0.3	0.7	-0.2	-0.3	-0.2	-0.0	0.8
Number of operations (self-reported)	0.2	0.4	0.8	-0.7	0.8	0.9	-0.5	0.5	-0.5	-0.2	-0.2	0.6
Irritability	0.2	0.3	0.9	0.4	1.0	0.5	0.3	0.4	-0.2	-0.4	-0.4	-0.7
Risk taking	0.2	0.4	1.1	-0.1	0.5	-0.5	-1.0	0.2	0.6	0.5	0.2	1.0
Age started oral contraceptive pill	0.2	0.3	0.9	0.5	0.7	0.2	-0.9	0.2	0.0	-0.2	-0.0	1.0
Cholesterol lowering medication	0.2	0.2	1.1	-0.4	0.6	1.0	0.2	0.5	-0.4	0.1	-0.2	0.0
Pack years of smoking	0.2	0.2	0.6	0.1	-0.6	-0.5	-0.8	0.2	-0.4	-0.6	-0.4	0.2
Leg fat mass (left)	0.2	0.9	2.3	1.0	1.5	0.8	0.5	-1.0	1.0	0.8	1.0	0.6
Alzheimer’s Disease (in father)	0.1	0.1	0.4	0.5	-0.3	-0.7	-0.6	-0.0	0.1	0.4	-0.1	0.3
Rheumatoid Arthritis	0.1	0.2	0.8	-0.9	-0.4	0.2	0.3	0.2	-0.3	0.2	-0.4	-0.2
Blood Platelet Count	0.1	0.9	2.1	-0.7	-0.2	1.3	0.9	0.9	-0.8	-1.4	-0.5	1.3
Medication: Metformin	0.1	0.1	0.5	0.2	-0.1	0.1	0.2	-0.1	0.7	0.0	0.4	-0.3
Fed-up feelings	0.1	0.1	0.5	0.0	-0.1	0.0	0.7	0.4	-0.4	-0.0	-0.2	-0.0
Multivitamins +/- minerals	0.1	0.1	0.4	0.6	-0.6	0.2	-0.2	0.2	-0.2	-0.0	-0.4	0.4
Allergy	0.1	0.3	1.2	-0.4	-1.1	-0.6	0.3	0.2	0.1	-0.5	-0.0	-0.9
Fluid intelligence score	0.1	0.2	1.1	0.1	-0.3	-1.0	0.2	0.5	-0.3	-0.2	-0.5	0.2
Arm fat mass (right)	0.1	0.4	1.6	0.4	0.8	0.1	1.3	-0.5	0.6	0.3	0.5	0.3
Leg fat percentage (right)	0.1	0.3	1.3	-0.2	1.2	0.3	0.2	0.6	-0.3	-0.3	-0.3	0.8
Wheeze or whistling in the chest in last year	0.1	0.2	0.4	0.5	0.2	0.5	0.5	-0.6	0.4	0.4	0.4	-0.2
Qualifications: College or University degree	0.1	0.3	0.9	-0.3	-0.1	-0.7	0.5	0.4	-0.4	-0.5	-0.7	0.9
Arm fat mass (left)	0.1	0.4	1.9	0.2	1.0	0.4	1.4	-0.4	0.4	0.2	0.5	0.2
Leg fat percentage (left)	0.1	0.4	0.8	-0.5	0.9	0.4	0.3	0.8	-0.6	-0.5	-0.6	0.6
Crohns Disease (2017)	0.0	0.1	0.3	-0.2	-0.2	-0.4	0.3	0.5	-0.2	-0.5	-0.2	-0.2
Hair Pigment	0.0	1.1	3.8	-1.2	0.3	1.2	2.0	0.5	-0.6	-0.9	-0.9	-0.7
Tanning	0.0	0.4	1.4	0.4	-0.2	-0.4	-0.2	0.4	-0.5	-0.8	-0.5	-1.2

Hub : Genes

PLCD1

Models

Trait associations