[Hub]/) : Traits : Comparative height size at age 10 :

chr3:182,846,387-186,041,982

Best TWAS P=4.34e-10 · Best GWAS P=8.55e-18 conditioned to 6.67e-20

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex ECE2 0.24 0.20 bslmm 542 0.19 1.6e-22 5.5 5.7 9.7e-09 0.04 0.93 0.07 FALSE
2 CommonMind Brain Pre-frontal Cortex SENP2 0.21 0.18 enet 33 0.19 4.2e-22 -5.7 6.2 6.7e-10 -0.11 1.00 0.00 TRUE
3 GTEx Artery Tibial PSMD2 0.13 0.09 lasso 5 0.08 1.3e-06 -5.1 5.2 1.5e-07 0.03 0.79 0.12 FALSE
4 GTEx Brain Cerebellum MAP6D1 0.38 0.27 enet 38 0.34 1.0e-10 3.3 -5.2 1.7e-07 0.02 0.98 0.00 TRUE
5 GTEx Skin Sun Exposed Lower leg PSMD2 0.13 0.14 lasso 4 0.15 1.4e-12 -5.1 5.2 2.0e-07 0.04 1.00 0.00 FALSE
6 The Cancer Genome Atlas Brain Lower Grade Glioma ECE2 0.04 0.02 blup 61 0.03 3.5e-04 5.6 6.2 6.6e-10 0.02 0.04 0.93 FALSE
7 The Cancer Genome Atlas Lung Adenocarcinoma PSMD2 0.09 0.02 blup 50 0.05 1.2e-06 -5.7 6.2 4.3e-10 0.06 0.14 0.30 TRUE
8 The Cancer Genome Atlas Testicular Germ Cell Tumors VWA5B2 0.10 0.04 blup 51 0.04 1.8e-02 4.2 -5.7 1.1e-08 -0.04 0.04 0.24 FALSE