[Hub]/) : Traits : Comparative height size at age 10 : ← →

chr4:305,291-2,437,290

Best TWAS P=7.63e-23 · Best GWAS P=5.06e-19 conditioned to 0.823

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
44	NTR	Blood	TACC3	0.05	0.03	lasso	9	0.04	2.7e-13	-8.0	9.8	7.6e-23	0.71	0.47	0.53	TRUE
41	NTR	Blood	CRIPAK	0.13	0.09	enet	31	0.15	1.5e-46	-4.2	-7.5	9.1e-14	0.00	1.00	0.00	TRUE
2	CommonMind	Brain Pre-frontal Cortex	TMEM129	0.11	0.07	enet	6	0.07	3.7e-09	-8.0	5.6	1.8e-08	0.35	0.85	0.15	TRUE
43	NTR	Blood	SLBP	0.04	0.02	lasso	5	0.02	2.8e-08	-8.0	9.7	2.9e-22	0.82	0.02	0.98	FALSE
36	GTEx	Whole Blood	TACC3	0.11	0.05	enet	7	0.06	2.8e-06	-7.6	8.2	3.5e-16	0.59	0.89	0.08	FALSE
47	YFS	Blood	SLBP	0.10	0.12	lasso	3	0.12	1.2e-35	-8.0	8.1	8.6e-16	0.60	0.87	0.13	FALSE
56	The Cancer Genome Atlas	Soft Tissue Sarcoma	TMEM129	0.09	0.04	lasso	2	0.03	3.8e-03	-7.6	-8.0	1.5e-15	-0.51	0.02	0.30	FALSE
54	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	TMEM129	0.05	0.03	lasso	4	0.02	8.5e-04	6.7	-7.8	7.5e-15	-0.69	0.13	0.46	FALSE
14	GTEx	Cells Transformed fibroblasts	TMEM129	0.14	0.02	lasso	3	0.02	6.0e-03	-7.3	-7.7	1.0e-14	-0.54	0.25	0.15	FALSE
29	GTEx	Pancreas	TMEM129	0.20	0.19	lasso	3	0.14	1.5e-06	-8.1	7.6	2.7e-14	0.58	0.76	0.17	FALSE
40	METSIM	Adipose	TMEM129	0.11	0.09	lasso	8	0.09	3.3e-13	-8.0	7.3	2.5e-13	0.57	0.86	0.14	FALSE
24	GTEx	Muscle Skeletal	SLBP	0.08	0.06	lasso	4	0.04	5.0e-05	-7.6	-7.2	6.0e-13	-0.35	0.92	0.01	FALSE
38	GTEx	Whole Blood	AC016773.1	0.27	0.21	enet	8	0.22	1.2e-19	-8.1	7.2	6.4e-13	0.53	0.83	0.17	FALSE
33	GTEx	Spleen	AC016773.1	0.42	0.21	lasso	7	0.16	8.6e-05	-8.0	6.6	4.9e-11	0.50	0.11	0.14	FALSE
42	NTR	Blood	KIAA1530	0.19	0.04	blup	345	0.10	9.1e-32	-4.3	-6.5	1.0e-10	0.08	1.00	0.00	FALSE
1	CommonMind	Brain Pre-frontal Cortex	CRIPAK	0.31	0.15	enet	34	0.26	1.2e-31	-4.2	-6.4	1.3e-10	0.04	1.00	0.00	FALSE
52	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	TMEM129	0.04	0.02	blup	47	0.02	3.0e-03	6.7	-6.4	1.9e-10	-0.70	0.03	0.43	FALSE
48	YFS	Blood	TACC3	0.22	0.24	lasso	11	0.27	1.4e-87	-8.1	6.3	3.3e-10	0.34	0.86	0.14	FALSE
15	GTEx	Colon Transverse	TMEM129	0.23	0.05	lasso	4	0.03	1.8e-02	-8.1	6.2	4.5e-10	0.51	0.08	0.10	FALSE
21	GTEx	Lung	CRIPAK	0.61	0.22	enet	46	0.41	1.1e-33	-4.2	-6.2	5.4e-10	0.02	1.00	0.00	FALSE
35	GTEx	Thyroid	AC016773.1	0.11	0.07	enet	7	0.06	3.9e-05	-8.0	6.2	6.0e-10	0.52	0.61	0.12	FALSE
26	GTEx	Nerve Tibial	CRIPAK	0.50	0.11	enet	76	0.38	1.1e-28	-4.1	-6.1	1.2e-09	-0.08	1.00	0.00	FALSE
8	GTEx	Brain Hippocampus	CRIPAK	0.48	0.22	lasso	4	0.23	4.0e-06	-4.1	-6.1	1.3e-09	0.00	0.18	0.12	FALSE
12	GTEx	Breast Mammary Tissue (Female)	CRIPAK	0.32	0.17	enet	29	0.26	2.7e-08	-4.0	-6.0	2.0e-09	0.01	0.54	0.02	FALSE
28	GTEx	Ovary	CRIPAK	0.43	0.27	enet	19	0.32	9.0e-09	-4.2	-6.0	2.7e-09	0.03	0.47	0.04	FALSE
58	The Cancer Genome Atlas	Thyroid Carcinoma	FAM53A	0.05	0.03	blup	56	0.04	1.8e-04	5.1	5.9	3.0e-09	0.79	0.01	0.95	FALSE
7	GTEx	Brain Cortex	CRIPAK	0.34	0.10	lasso	6	0.18	9.5e-06	-4.2	-5.9	3.8e-09	0.03	0.20	0.06	FALSE
11	GTEx	Breast Mammary Tissue	CRIPAK	0.42	0.12	enet	35	0.39	5.2e-21	-4.2	-5.8	7.3e-09	0.02	1.00	0.00	FALSE
55	The Cancer Genome Atlas	Pheochromocytoma and Paraganglioma	TACC3	0.09	0.08	enet	7	0.11	2.7e-05	-8.0	5.8	7.6e-09	0.52	0.13	0.23	FALSE
6	GTEx	Brain Cortex	TACC3	0.26	0.13	lasso	4	0.17	1.7e-05	-8.1	5.7	9.3e-09	0.52	0.25	0.27	FALSE
51	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	CRIPAK	0.28	0.16	blup	28	0.19	3.2e-21	-4.1	-5.7	1.1e-08	0.03	0.01	0.84	FALSE
39	METSIM	Adipose	CRIPAK	0.28	0.16	bslmm	335	0.25	2.7e-37	-3.6	-5.7	1.2e-08	-0.01	1.00	0.00	FALSE
37	GTEx	Whole Blood	CRIPAK	0.38	0.17	lasso	9	0.28	3.4e-26	-4.1	-5.7	1.4e-08	0.02	1.00	0.00	FALSE
46	YFS	Blood	CRIPAK	0.35	0.27	bslmm	301	0.33	6.0e-112	-4.1	-5.7	1.4e-08	-0.03	1.00	0.00	FALSE
45	ROSMAP	Brain Pre-frontal Cortex	AC016773.1	0.12	0.06	lasso	3	0.10	3.0e-12	-8.0	5.7	1.5e-08	0.52	0.93	0.07	FALSE
4	GTEx	Artery Aorta	UVSSA	0.33	0.06	enet	30	0.28	7.2e-16	-4.3	-5.6	2.5e-08	0.01	0.95	0.00	FALSE
3	GTEx	Adipose Visceral Omentum	CRIPAK	0.47	0.24	lasso	12	0.31	1.3e-16	-4.2	-5.5	3.8e-08	0.02	1.00	0.00	FALSE
57	The Cancer Genome Atlas	Thyroid Carcinoma	CRIPAK	0.38	0.22	enet	12	0.25	5.4e-24	-4.1	-5.5	4.0e-08	0.01	0.01	0.84	FALSE
22	GTEx	Lung	RP11-20I20.4	0.07	0.00	lasso	3	0.01	6.0e-02	-4.9	-5.5	4.1e-08	0.03	0.13	0.06	FALSE
50	The Cancer Genome Atlas	Colon Adenocarcinoma	CRIPAK	0.38	0.16	blup	28	0.21	2.8e-12	-4.1	-5.4	5.7e-08	0.01	0.01	0.84	FALSE
49	The Cancer Genome Atlas	Breast Invasive Carcinoma	CRIPAK	0.22	0.11	blup	28	0.14	5.6e-28	-4.1	-5.4	5.9e-08	0.01	0.01	0.84	FALSE
16	GTEx	Colon Transverse	CRIPAK	0.33	0.10	enet	22	0.24	5.8e-12	-4.1	-5.4	6.1e-08	0.03	0.97	0.00	FALSE
30	GTEx	Pancreas	CRIPAK	0.34	0.13	lasso	6	0.27	1.0e-11	-4.1	-5.4	6.1e-08	0.01	0.84	0.01	FALSE
5	GTEx	Artery Tibial	CRIPAK	0.42	0.09	enet	50	0.34	1.3e-27	1.5	-5.4	7.6e-08	0.02	1.00	0.00	FALSE
27	GTEx	Ovary	UVSSA	0.33	0.10	enet	12	0.32	1.5e-08	-4.3	-5.4	8.2e-08	0.02	0.11	0.05	FALSE
31	GTEx	Pituitary	TACC3	0.37	0.17	lasso	2	0.26	4.3e-07	-8.1	5.3	9.1e-08	0.23	0.33	0.09	FALSE
32	GTEx	Skin Sun Exposed Lower leg	CRIPAK	0.36	0.09	enet	40	0.35	8.7e-30	-4.2	-5.3	9.4e-08	0.03	1.00	0.00	FALSE
23	GTEx	Muscle Skeletal	FGFRL1	0.14	0.08	lasso	4	0.06	3.7e-06	-5.6	5.3	9.6e-08	0.01	0.00	1.00	FALSE
10	GTEx	Brain Nucleus accumbens basal ganglia	CRIPAK	0.34	0.13	lasso	6	0.25	2.7e-07	-4.2	-5.3	1.1e-07	0.05	0.21	0.04	FALSE
13	GTEx	Cells EBV-transformed lymphocytes	CRIPAK	0.49	0.27	lasso	8	0.35	2.9e-12	-4.2	-5.3	1.1e-07	0.05	0.84	0.01	FALSE
18	GTEx	Esophagus Gastroesophageal Junction	UVSSA	0.30	0.00	enet	23	0.08	1.1e-03	-4.2	-5.3	1.2e-07	0.09	0.28	0.04	FALSE
25	GTEx	Muscle Skeletal	CRIPAK	0.25	0.11	enet	32	0.18	7.6e-18	-4.2	-5.3	1.2e-07	0.03	1.00	0.00	FALSE
20	GTEx	Esophagus Mucosa	CRIPAK	0.49	0.14	enet	28	0.40	6.8e-29	-4.2	-5.3	1.3e-07	0.00	1.00	0.00	FALSE
53	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	CRIPAK	0.21	0.10	enet	9	0.15	1.3e-16	-4.1	-5.2	1.7e-07	0.00	0.01	0.82	FALSE
59	The Cancer Genome Atlas	Thyroid Carcinoma	TMEM129	0.20	0.21	lasso	5	0.24	3.5e-23	-1.7	5.2	2.0e-07	0.49	1.00	0.00	FALSE
9	GTEx	Brain Hypothalamus	CRIPAK	0.22	0.00	lasso	5	0.01	2.1e-01	-4.3	-5.2	2.2e-07	0.02	0.06	0.08	FALSE
17	GTEx	Colon Transverse	RP11-20I20.4	0.17	0.05	lasso	3	0.05	2.3e-03	-4.9	-5.1	2.7e-07	0.01	0.30	0.30	FALSE
34	GTEx	Testis	TACC3	0.17	0.03	lasso	6	0.04	5.2e-03	-8.0	-5.1	2.8e-07	-0.21	0.20	0.07	FALSE
19	GTEx	Esophagus Gastroesophageal Junction	CRIPAK	0.33	0.20	lasso	5	0.30	1.4e-11	-4.2	-5.1	3.0e-07	0.02	0.99	0.00	FALSE