Best TWAS P=4.94e-33 · Best GWAS P=6.39e-83 conditioned to 3.7e-50
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | OTUD4 | 0.06 | 0.04 | bslmm | 272 | 0.04 | 2.6e-05 | -7.7 | -6.3 | 3.9e-10 | 0.31 | 0.85 | 0.03 | TRUE |
| 2 | GTEx | Brain Hypothalamus | HHIP-AS1 | 0.12 | 0.02 | enet | 16 | 0.04 | 4.6e-02 | 8.9 | 8.8 | 1.7e-18 | -0.22 | 0.06 | 0.13 | TRUE |
| 3 | GTEx | Pancreas | ANAPC10 | 0.14 | 0.10 | lasso | 3 | 0.10 | 4.3e-05 | -12.5 | 12.0 | 4.9e-33 | -0.39 | 0.32 | 0.12 | TRUE |
| 4 | ROSMAP | Brain Pre-frontal Cortex | OTUD4 | 0.04 | 0.03 | lasso | 2 | 0.03 | 1.4e-04 | 9.8 | -10.1 | 5.8e-24 | 0.31 | 0.66 | 0.02 | TRUE |