TWAS hub - CCNA2

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	TCGA	Cervical Squamous Cell Carcinoma	0.1060	0.0600	0.00810	-0.005	-0.003	0.018	NA	-0.002	0.780	0.5100	0.0440	NA	0.430
2	TCGA	Head and Neck Squamous Cell Carcinoma	0.0338	0.0179	0.00071	0.011	0.022	0.016	NA	0.012	0.018	0.0015	0.0057	NA	0.015

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2
Leg fat-free mass (right)	10.2	54.6	78.1	5.6	8.8
Leg predicted mass (right)	10.2	54.2	78.1	5.5	8.8
Leg fat-free mass (left)	9.9	52.6	74.8	5.5	8.7
Basal metabolic rate	9.9	54.9	79.7	5.5	8.9
Leg predicted mass (left)	9.7	51.2	73.3	5.4	8.6
Whole body water mass	9.6	54.9	79.7	5.5	8.9
Whole body fat-free mass	9.4	53.5	77.3	5.5	8.8
Trunk fat-free mass	9.2	52.8	75.7	5.5	8.7
Trunk predicted mass	9.0	51.5	74.0	5.4	8.6
Arm predicted mass (left)	9.0	46.0	67.7	4.9	8.2
Weight	8.6	42.3	60.8	4.9	7.8
Arm fat-free mass (left)	8.5	43.1	64.0	4.7	8.0
Hip circumference	8.4	36.4	51.6	4.6	7.2
Arm predicted mass (right)	8.3	42.4	64.2	4.5	8.0
Arm fat-free mass (right)	8.1	41.4	62.2	4.5	7.9
Height	6.7	129.0	207.4	7.1	14.4
Comparative height size at age 10	6.0	33.0	45.6	4.5	6.8
Peak expiratory flow (PEF)	5.6	13.1	15.2	3.3	3.9
Arm fat mass (right)	5.5	22.6	33.9	3.4	5.8
Trunk fat mass	5.2	22.5	34.4	3.2	5.9
Standing height	5.2	51.5	75.7	5.2	8.7
Arm fat mass (left)	5.2	21.4	32.5	3.2	5.7
Major Depression (MDD)	5.1	6.2	9.2	1.8	3.0
Whole body fat mass	4.9	20.6	31.5	3.1	5.6
Blood Red Count	4.7	44.9	64.2	5.1	8.0
Basal cell carcinoma (self-reported)	4.7	5.6	6.4	-2.2	-2.5
Chronotype (morning person)	4.4	10.1	18.8	-1.2	-4.3
Impedance of leg (right)	4.4	21.4	30.9	-3.4	-5.6
Waist circumference	4.4	16.1	26.4	2.4	5.1
Number of self-reported non-cancer illnesses	4.3	7.5	13.5	1.2	3.7
Leg fat mass (left)	4.3	16.8	24.5	3.0	5.0
Impedance of leg (left)	4.1	19.8	29.0	-3.3	-5.4
Health satisfaction	4.0	5.2	9.1	1.1	3.0
Commuting to job workplace: Walk	4.0	4.3	8.2	-2.9	-0.6
Sitting height	3.9	27.5	40.3	3.8	6.3
High blood pressure (siblings)	3.9	5.6	6.2	2.5	2.2
Number of full sisters	3.9	4.7	8.8	-0.8	-3.0
Breastfed as a baby	3.8	4.7	9.2	-0.4	-3.0
Leg fat mass (right)	3.7	14.5	21.6	2.7	4.7
Medication: Gliclazide	3.7	4.2	7.2	-1.1	-2.7
Pulse wave reflection index	3.6	4.5	5.4	2.3	1.9
Impedance of whole body	3.6	18.4	26.5	-3.2	-5.1
Alcohol intake versus 10 years previously	3.5	5.3	5.7	2.2	2.4
Pulse wave Arterial Stiffness index	3.5	4.1	4.8	1.9	2.2
Severe depression (siblings)	3.2	3.6	6.8	-0.6	-2.6
Time employed in main current job	3.2	3.7	5.7	2.4	1.3
Medication: Blood pressure	3.2	6.0	7.9	2.0	2.8
Body mass index (BMI)	3.1	13.2	18.5	2.8	4.3
Birth weight of first child	2.9	5.3	7.8	1.7	2.8
Lung FEV1/FVC ratio	2.8	14.4	17.9	3.3	4.2
Medication: Allopurinol	2.7	3.5	4.4	-2.1	-1.6
Trunk fat percentage	2.5	9.9	15.7	2.0	4.0
Illnesses of siblings	2.4	3.3	3.4	-1.8	-1.8
Shortness of breath walking on level ground	2.4	2.9	5.1	0.8	2.2
Emphysema/chronic bronchitis	2.4	2.7	4.5	1.0	2.1
LDL Cholesterol	2.3	3.6	7.3	0.0	-2.7
Hearing difficulty/problems with background noise	2.3	3.7	7.3	2.7	0.5
Arm fat percentage (right)	2.3	8.9	13.9	2.0	3.7
Forced expiratory volume in 1-second (FEV1)	2.3	7.9	9.9	3.1	2.4
Impedance of arm (left)	2.3	10.7	15.7	-2.4	-4.0
Ever had stillbirth, spontaneous miscarriage or termination	2.3	2.5	3.1	-1.8	-1.4
Eye problems/disorders: Cataract	2.3	2.6	5.2	-0.4	2.3
Mother’s age at death	2.3	2.8	3.1	-1.6	-1.8
BMI	2.2	12.9	18.0	2.8	4.2
Waist Hip Ratio (WHR)	2.2	10.0	16.3	-4.0	-1.9
Frequency of unenthusiasm / disinterest in last 2 weeks	2.2	3.0	5.4	0.7	2.3
Had other major operations	2.2	2.6	3.5	1.9	1.3
Impedance of arm (right)	2.2	10.3	15.1	-2.3	-3.9
Noisy workplace	2.2	2.8	4.8	-0.8	-2.2
Arm fat percentage (left)	2.2	8.9	14.2	1.9	3.8
Medication for cholesterol	2.2	3.3	4.4	-1.5	-2.1
Medication: Omeprazole	2.1	2.5	3.6	1.9	1.2
Back pain experienced in last month	2.1	3.0	3.4	1.6	1.9
Medication: Bendroflumethiazide	2.1	3.2	5.7	0.9	2.4
Alcohol drinker status: Never	2.1	2.5	3.3	1.8	1.3
Long-standing illness, disability or infirmity	2.0	3.1	6.1	-0.0	2.5
Frequency of depressed mood in last 2 weeks	1.9	2.7	4.2	1.1	2.0
Qualifications: A levels/AS levels or equivalent	1.9	4.3	7.5	-1.0	-2.7
Body fat percentage	1.9	7.5	12.2	1.7	3.5
Pulse rate, automated reading	1.9	6.3	10.0	-3.2	-1.6
Taking other prescription medications	1.8	2.7	4.4	1.1	2.1
Frequency of tiredness / lethargy in last 2 weeks	1.8	3.0	4.9	1.0	2.2
Wheeze or whistling in the chest in last year	1.8	3.2	4.6	1.4	2.1
Pulse wave peak to peak time	1.8	2.1	2.3	-1.4	-1.5
Ever had bowel cancer screening	1.8	2.1	3.7	0.8	1.9
Alzheimer’s Disease (in mother)	1.7	2.0	2.1	1.3	1.5
Ever had prostate specific antigen (PSA) test	1.7	1.9	2.7	1.6	1.1
Supplements: Calcium	1.7	1.9	3.7	-0.3	1.9
Number of treatments/medications taken	1.6	2.8	5.3	0.5	2.3
Pain experienced in last month	1.6	2.7	2.9	-1.6	-1.7
Alzheimer’s Disease (including proxy)	1.5	2.2	3.2	1.8	1.1
Verbal and Numeric Reasoning (VNR)	1.5	3.5	4.0	-2.0	-1.7
Breast Cancer	1.5	3.6	5.3	1.4	2.3
Forced expiratory volume in 1-second (FEV1), predicted	1.5	3.1	3.2	1.7	1.8
Smoking status: Current	1.5	2.4	3.5	1.9	1.1
Eye problems/disorders: Glaucoma	1.5	1.7	3.3	-1.8	0.3
Diastolic blood pressure, automated reading	1.5	4.6	6.0	1.8	2.4
Supplements: Zinc	1.4	1.5	3.0	0.3	1.7
Fed-up feelings	1.4	2.5	4.7	0.6	2.2
Heel bone mineral density (BMD) T-score, automated (left)	1.4	3.2	6.4	-0.0	2.5
Qualifications: None of the above	1.4	3.0	5.3	0.9	2.3
Mouth/teeth dental problems: Mouth ulcers	1.4	2.2	3.2	1.8	1.1
Ever taken oral contraceptive pill	1.4	1.6	3.2	0.1	-1.8
Leg fat percentage (left)	1.4	5.2	7.8	1.6	2.8
Deep venous thrombosis (DVT) (self-reported)	1.4	1.7	3.3	0.4	1.8
Prostate Cancer	1.3	1.8	3.3	1.8	0.5
Ulcerative Colitis	1.3	1.9	3.3	1.8	0.7
Angina	1.3	1.7	3.3	-1.8	-0.2
Current tobacco smoking	1.3	2.2	3.4	1.8	1.0
High blood pressure	1.3	3.7	5.1	1.5	2.2
Forced vital capacity (FVC)	1.3	5.2	5.2	2.2	2.3
Mouth/teeth dental problems: Bleeding gums	1.3	1.7	3.4	0.2	-1.9
Gout (self-reported)	1.3	1.7	2.9	-1.7	-0.8
Overall health rating	1.3	2.9	5.2	0.7	2.3
Family relationship satisfaction	1.3	1.6	3.2	-1.8	-0.1
Vascular/heart problems diagnosed by doctor	1.3	3.5	5.1	-1.3	-2.3
Fluid intelligence score	1.2	2.5	4.1	-2.0	-1.0
Forced expiratory volume in 1-second (FEV1), Best measure	1.2	3.9	4.4	2.1	1.8
Blood clot in the leg (DVT)	1.2	1.5	2.9	0.3	1.7
Medication: Lisinopril	1.2	1.6	3.0	1.7	0.4
Age started oral contraceptive pill	1.2	1.5	2.8	-1.7	0.5
Bipolar Disorder (2018)	1.1	1.7	2.7	-1.6	-0.8
Reaction Time	1.1	2.0	3.0	1.0	1.7
Lupus	1.1	1.6	3.0	1.7	0.4
Allergy	1.1	2.5	3.5	-1.2	-1.9
Number of live births	1.1	1.5	1.9	-1.4	-1.0
Medication: Lansoprazole	1.1	1.2	1.3	-1.1	-1.1
Hair/balding pattern: Pattern 4	1.1	2.6	2.6	-1.6	-1.6
Angina (self-reported)	1.1	1.5	2.8	-1.7	-0.3
Supplements: Vitamin C	1.1	1.3	1.5	-1.1	-1.2
Worry (Nagel 2018)	1.0	2.1	2.4	-1.3	-1.6
Body Mass Index (BMI) (2010)	1.0	1.3	1.8	1.4	0.9
Neuroticism (2016)	1.0	1.5	2.8	0.3	1.7
Blood Platelet Count	1.0	11.4	21.1	1.3	4.6
Bilateral oophorectomy (both ovaries removed)	1.0	1.2	2.2	0.4	1.5
Multivitamins +/- minerals	1.0	1.3	2.3	0.5	1.5
High blood pressure (mother)	1.0	1.4	1.7	-1.1	1.3
Number of incorrect matches in round	1.0	1.7	1.8	-1.3	1.3
Nervous feelings	1.0	2.0	2.1	-1.5	-1.3
Hayfever/allergic rhinitis (self-reported)	1.0	1.4	2.6	-0.4	1.6
Medication: Ramipril	1.0	1.2	2.5	0.0	1.6
Headache pain in last month	1.0	1.8	2.7	1.7	0.9
Glaucoma (self-reported)	1.0	1.2	2.3	-1.5	0.1
Medication: Amlodipine	1.0	1.4	1.8	1.3	0.9
Medication: Ventolin 100micrograms inhaler	1.0	1.3	2.6	-0.1	1.6
Leg fat percentage (right)	1.0	3.6	5.8	1.2	2.4
Age at first live birth	1.0	1.8	3.2	-1.8	-0.6
Commuting to job workplace: Car/motor vehicle	1.0	1.2	1.9	0.7	-1.4
Breast cancer (self-reported)	1.0	1.2	2.4	0.2	1.6
Medication: Omeprazole (e.g. Zanprol)	1.0	1.2	2.2	1.5	0.4
Heart disease (siblings)	1.0	1.3	2.2	0.6	1.5
Alzheimer’s Disease (in father)	0.9	1.0	1.7	1.3	0.5
Smoking Status	0.9	2.3	3.2	1.8	1.2
Ever had hysterectomy (womb removed)	0.9	1.0	2.0	-0.3	1.4
Medication: Co-codamol	0.9	1.1	1.4	-0.9	1.2
Relative age voice broke	0.9	1.4	1.7	-1.3	-1.1
Forced vital capacity (FVC), Best measure	0.9	3.2	4.2	1.5	2.0
Qualifications: College or University degree	0.9	3.0	5.4	-0.7	-2.3
Eye problems/disorders: None of the above	0.9	1.1	1.6	0.7	-1.3
Friendships satisfaction	0.9	1.1	2.2	-1.5	0.3
Ulcerative Colitis (UC)	0.8	1.4	1.9	1.0	1.4
Other serious medical condition/disability diagnosed by doctor	0.8	1.0	1.6	-1.3	0.7
Ever used hormone-replacement therapy (HRT)	0.8	1.1	1.3	-1.1	-0.9
Diabetes (mother)	0.8	1.0	1.1	0.9	1.1
Qualifications: CSEs or equivalent	0.8	1.1	1.9	-1.4	0.4
Diverticular disease/diverticulitis (self-reported)	0.8	0.9	1.6	-1.3	-0.5
Illnesses of mother	0.8	1.0	1.8	-0.4	-1.3
Leg pain on walking	0.8	0.9	1.4	0.7	1.2
Illnesses of siblings: Diabetes	0.8	1.0	2.0	1.4	-0.0
Depression (Nagel 2018)	0.7	1.1	1.8	0.6	1.3
HbA1C	0.7	0.8	1.5	-1.2	-0.2
Rheumatoid Arthritis	0.7	0.9	1.7	0.4	1.3
Vitamin and mineral supplements	0.7	0.9	1.2	-0.8	-1.1
Maternal smoking around birth	0.7	1.0	1.6	-0.7	1.3
Heel bone mineral density (BMD) T-score, automated (right)	0.7	1.7	3.2	-0.4	1.8
Happiness	0.7	0.8	1.5	-0.3	1.2
Prospective memory result	0.7	0.9	1.7	-1.3	0.3
Length of working week for main job	0.7	0.8	1.5	-0.3	-1.2
Worry too long after embarrassment	0.7	1.1	2.3	-1.5	0.2
Medication: Blood pressure	0.7	1.3	2.3	0.6	1.5
Qualifications: NVQ or HND or HNC or equivalent	0.7	0.9	1.5	-0.4	-1.2
Hypertension (Self-reported)	0.7	1.9	3.1	0.9	1.8
Qualifications: nursing, teaching	0.7	1.1	2.3	-1.5	0.1
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.7	0.8	1.0	-1.0	0.8
Average weekly champagne plus white wine intake	0.7	1.0	1.3	-1.1	0.9
Medication: Atorvastatin	0.7	0.9	1.4	1.2	0.6
Average weekly beer plus cider intake	0.7	1.0	1.7	0.6	1.3
Myopia	0.7	1.0	2.0	1.4	0.1
Townsend deprivation index at recruitment	0.6	0.8	0.9	0.9	1.0
Exposure to tobacco smoke at home	0.6	0.7	1.2	-1.1	-0.4
Ever highly irritable/argumentative for 2 days	0.6	0.7	1.3	-1.1	0.2
Alcohol intake frequency.	0.6	1.4	2.6	0.4	1.6
Age at last live birth	0.6	0.8	1.6	-1.3	-0.3
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.6	0.7	1.1	1.0	-0.6
Smoking status: Previous	0.6	0.9	1.5	-0.4	-1.2
Asthma (self-reported)	0.6	1.1	2.2	0.3	1.5
Illnesses of father: None of the above (group 1)	0.6	0.7	1.3	-0.5	1.1
High cholesterol (Self-reported)	0.6	1.0	1.6	1.3	0.7
Number of operations (self-reported)	0.6	0.9	0.9	1.0	0.9
Bipolar Disorder or Schizophrenia	0.5	1.2	2.5	-1.6	0.1
Ovarian Cancer	0.5	0.6	1.2	-1.1	-0.0
Triglycerides	0.5	0.8	1.6	-0.0	-1.3
Type 2 Diabetes (T2D) (2012)	0.5	0.6	1.2	-0.1	1.1
Respiratory disease	0.5	1.1	2.0	0.5	1.4
Tinnitus: Yes, but not now, but have in the past	0.5	0.5	0.5	-0.7	0.7
Alcohol usually taken with meals	0.5	0.7	1.0	-0.7	-1.0
Heart attack	0.5	0.7	1.1	-0.5	-1.0
Pain all over the body in last month	0.5	0.5	1.0	-0.1	1.0
Serious illness, injury or assault of a close relative in last 2 years	0.5	0.5	1.0	-0.2	-1.0
Asthma	0.5	0.9	1.7	0.3	1.3
Medication: Ibuprofen (e.g. Nurofen)	0.5	0.7	1.3	-0.3	-1.1
Medication for cholesterol, blood pressure or diabetes	0.5	0.8	1.2	-0.6	-1.1
Mouth/teeth dental problems: Loose teeth	0.5	0.5	0.8	0.5	-0.9
Heart disease (mother)	0.5	0.7	0.8	-0.9	-0.7
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.5	0.6	1.2	-1.1	-0.2
Medication: Aspirin	0.5	0.7	1.3	0.3	1.1
Commuting to job workplace: Public transport	0.5	0.6	0.7	-0.7	0.8
Illnesses of father: High blood pressure	0.5	0.7	0.8	0.9	0.7
Alcohol drinker status: Previous	0.5	0.6	1.2	-1.1	-0.1
Neuroticism (Nagel 2018)	0.4	0.9	1.5	-1.2	-0.4
Irritable Bowel Disease (IBD)	0.4	1.0	1.9	0.2	1.4
Cardiovascular Disease	0.4	1.3	1.6	1.0	1.3
Hearing difficulty/problems: Yes	0.4	0.7	1.3	0.2	-1.1
Medication for hormone replacement therapy	0.4	0.5	0.9	-0.2	1.0
Father’s age at death	0.4	0.5	0.6	-0.7	-0.8
Worrier / anxious feelings	0.4	0.8	0.8	-0.9	-0.9
Depression (self-reported)	0.4	0.5	0.7	0.4	-0.9
Qualifications: O levels/GCSEs or equivalent	0.4	0.7	1.3	1.1	-0.3
Exposure to tobacco smoke outside home	0.4	0.5	0.7	0.5	0.8
Medication: Seretide 50 evohaler	0.4	0.5	0.9	-0.3	0.9
Mean time to correctly identify matches	0.4	0.7	1.3	0.3	1.1
Loneliness, isolation	0.4	0.5	0.7	0.8	0.6
Medication: Aspirin	0.4	0.6	1.1	0.2	1.0
Supplements: Fish oil (including cod liver oil)	0.4	0.5	0.7	-0.5	-0.8
Ever smoked	0.4	0.7	1.1	1.0	-0.5
Risk taking	0.4	0.6	1.1	0.3	-1.1
Heart attack/myocardial infarction (self-reported)	0.4	0.5	0.7	-0.5	-0.8
Intelligence (Savage-Jansen 2018)	0.3	1.1	2.1	-1.5	0.0
Schizophrenia (2018)	0.3	0.7	0.9	-1.0	0.7
Schizophrenia vs Biploar Disorder	0.3	0.4	0.7	-0.1	0.8
Age at First Birth	0.3	0.4	0.7	-0.8	0.3
Fasting Glucose	0.3	0.3	0.4	0.7	0.5
Schizophrenia (2014)	0.3	0.7	0.9	-0.9	0.7
Neuroticism	0.3	0.8	1.5	-1.2	0.1
Medication: Metformin	0.3	0.5	0.9	-1.0	0.1
Diabetes (father)	0.3	0.4	0.6	0.8	-0.4
Pack years adult smoking proportion	0.3	0.4	0.8	0.3	-0.9
Hand grip strength (right)	0.3	0.8	1.0	0.8	1.0
Age when periods started (menarche)	0.3	0.7	1.3	-0.3	-1.1
Stomach or abdominal pain in last month	0.3	0.4	0.8	-0.1	0.9
Supplements: Glucosamine	0.3	0.4	0.5	-0.7	0.5
Medication: Levothyroxine sodium	0.3	0.6	1.0	-0.3	1.0
Frequency of tenseness / restlessness in last 2 weeks	0.3	0.5	0.9	0.3	1.0
Had menopause	0.3	0.4	0.4	-0.6	-0.7
Financial difficulties in last 2 years	0.3	0.4	0.5	0.5	0.7
Mouth/teeth dental problems	0.3	0.5	1.0	-1.0	-0.0
Medication: Simvastatin	0.3	0.4	0.8	-0.3	0.9
Mouth/teeth dental problems: Dentures	0.3	0.5	0.7	-0.5	0.9
Tense / ‘highly strung’	0.3	0.4	0.6	0.8	-0.6
Seen a psychiatrist for nerves, anxiety, tension or depression	0.3	0.4	0.9	-0.0	-0.9
Number of children fathered	0.3	0.3	0.4	0.5	0.6
Had major operations	0.3	0.3	0.4	0.7	0.5
Knee pain experienced in last month	0.3	0.4	0.5	-0.7	-0.6
Illnesses of father: Heart disease	0.3	0.4	0.8	0.9	-0.4
Average weekly red wine intake	0.3	0.4	0.6	0.8	-0.5
Mineral and other dietary supplements	0.3	0.4	0.8	0.2	-0.9
Guilty feelings	0.3	0.4	0.5	-0.7	0.6
Hearing aid user	0.3	0.3	0.5	-0.4	-0.7
Pain type(s) experienced in last month: Hip pain	0.3	0.4	0.7	-0.8	0.4
Cholesterol lowering medication	0.3	0.4	0.8	0.3	0.9
Crohns Disease (2017)	0.2	0.5	0.6	-0.5	0.8
Bipolar Disorder (2011)	0.2	0.2	0.5	0.1	0.7
Mean Putamen Volume	0.2	0.2	0.2	0.5	-0.5
HDL Cholesterol	0.2	0.4	0.7	-0.9	-0.2
Blood White Count	0.2	1.2	1.8	-0.7	-1.3
Heel T-Score	0.2	1.6	2.8	-0.7	-1.7
Systolic Blood Pressure	0.2	1.1	1.6	-1.2	0.8
Hypothyroidism (self reported)	0.2	0.5	0.6	0.6	0.8
Hand grip strength (left)	0.2	0.6	0.9	0.9	0.5
Past tobacco smoking	0.2	0.3	0.6	-0.2	0.8
Hair/balding pattern: Pattern 2	0.2	0.3	0.4	0.5	-0.6
Hair/balding pattern: Pattern 3	0.2	0.3	0.3	-0.6	0.5
Pulse rate	0.2	0.4	0.6	-0.8	0.5
Lung cancer (father)	0.2	0.3	0.5	0.7	0.1
Medication: Paracetamol	0.2	0.3	0.4	-0.3	-0.6
Hypothyroidism/myxoedema (self-reported)	0.2	0.5	0.9	-0.0	1.0
Reason for reducing amount of alcohol drunk: Health precaution	0.2	0.2	0.3	0.1	0.6
Migraine (self-reported)	0.2	0.2	0.4	0.6	0.1
Illness, injury, bereavement, stress in last 2 years	0.2	0.3	0.4	-0.6	-0.4
Osteoporosis (self-reported)	0.2	0.2	0.3	0.5	-0.4
Fractured/broken bones in last 5 years	0.2	0.2	0.4	0.1	-0.6
Commuting to job workplace: Cycle	0.2	0.2	0.4	-0.6	-0.4
Pack years of smoking	0.2	0.3	0.7	-0.0	-0.8
Depressed Affect (Nagel 2018)	0.1	0.3	0.5	0.3	0.7
Crohns Disease (2012)	0.1	0.1	0.1	0.4	-0.2
Type 2 Diabetes (T2D) (2018)	0.1	0.3	0.5	0.7	-0.1
Lung FVC	0.1	0.4	0.7	0.0	-0.8
Tanning	0.1	1.0	1.8	0.5	-1.3
Average weekly spirits intake	0.1	0.1	0.2	0.2	-0.4
Sensitivity / hurt feelings	0.1	0.1	0.2	-0.5	-0.0
Relative age of first facial hair	0.1	0.2	0.5	0.7	-0.1
Systolic blood pressure, automated reading	0.1	0.2	0.4	-0.0	0.6
Eye problems/disorders: Diabetes related eye disease	0.1	0.1	0.1	-0.2	-0.4
Serious illness, injury or assault to yourself	0.1	0.1	0.1	0.2	-0.3
Ever unenthusiastic/disinterested for a whole week	0.1	0.2	0.2	0.3	0.4
Diabetes (self-reported)	0.1	0.1	0.2	0.5	0.2
Neuroticism score	0.1	0.2	0.2	-0.4	0.5
Falls in the last year	0.1	0.2	0.3	-0.6	-0.2
Medication: Cholesterol lowering	0.1	0.1	0.1	-0.3	-0.3
Loud music exposure frequency	0.1	0.1	0.2	0.2	0.4
Birth weight	0.1	0.3	0.6	0.1	-0.8
Chronic bronchitis/emphysema (mother)	0.1	0.1	0.2	-0.3	0.4
Number of full brothers	0.1	0.1	0.1	-0.4	0.0
Medication for pain relief, constipation, heartburn	0.1	0.2	0.3	-0.6	-0.1
Neck or shoulder pain in last month	0.1	0.1	0.1	0.2	-0.4
Medication: Ibuprofen	0.1	0.1	0.2	0.5	0.1
Suffer from ‘nerves’	0.1	0.1	0.1	0.4	0.2
Handedness (chirality/laterality): Left-handed	0.1	0.1	0.2	0.5	-0.2
Mood swings	0.1	0.1	0.2	-0.3	-0.4
Osteoarthritis (self-reported)	0.1	0.1	0.1	0.1	-0.4
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.1	0.1	0.2	-0.2	-0.5
Miserableness	0.1	0.1	0.2	0.4	0.1
Wears glasses or contact lenses	0.1	0.2	0.2	0.5	-0.2
Financial situation satisfaction	0.1	0.2	0.3	-0.6	-0.0
Tinnitus: Yes, now most or all of the time	0.1	0.1	0.2	-0.4	-0.1
Irritability	0.1	0.1	0.2	-0.5	0.2
Ever depressed for a whole week	0.1	0.1	0.2	-0.3	-0.4
Unable to work because of sickness or disability	0.1	0.2	0.3	-0.5	-0.2
Coronary Artery Disease (CAD)	0.0	0.0	0.0	0.1	0.0
Primary Biliary Cirrhosis	0.0	0.1	0.1	-0.1	0.3
Blood Eosinophil Count	0.0	0.3	0.7	-0.0	-0.8
Allergy or Eczema	0.0	0.1	0.2	-0.2	0.5
Hair Pigment	0.0	0.2	0.4	0.0	0.6
Average weekly fortified wine intake	0.0	0.0	0.0	0.0	0.1
Hayfever, allergic rhinitis or eczema	0.0	0.1	0.1	0.2	0.4
Medication: Atenolol	0.0	0.0	0.0	-0.1	0.1
Chronic bronchitis/emphysema (father)	0.0	0.1	0.1	-0.3	-0.1
Seen doctor (GP) for nerves, anxiety, tension or depression	0.0	0.1	0.1	0.1	0.3
Comparative body size at age 10	0.0	0.1	0.1	0.3	-0.1
Chest pain or discomfort	0.0	0.1	0.1	0.3	0.2
Diabetes diagnosed by doctor	0.0	0.0	0.1	0.0	-0.2
Medication: Paracetamol	0.0	0.0	0.0	-0.1	-0.1

Hub : Genes

CCNA2

Models

Trait associations