Best TWAS P=5.4e-12 · Best GWAS P=1.3e-17 conditioned to 3.51e-07
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | GHR | 0.25 | 0.07 | bslmm | 382 | 0.13 | 2.6e-15 | -6.0 | 5.3 | 1.5e-07 | -0.61 | 0.02 | 0.98 | FALSE |
| 2 | GTEx | Adipose Subcutaneous | CCDC152 | 0.09 | 0.04 | lasso | 4 | 0.02 | 6.4e-03 | 5.8 | 5.8 | 5.8e-09 | -0.56 | 0.85 | 0.04 | FALSE |
| 3 | GTEx | Artery Coronary | CCDC152 | 0.20 | 0.13 | lasso | 2 | 0.12 | 7.7e-05 | 5.8 | 5.9 | 3.9e-09 | -0.58 | 0.63 | 0.10 | FALSE |
| 4 | GTEx | Stomach | SERBP1P6 | 0.12 | 0.03 | enet | 16 | 0.01 | 6.7e-02 | -4.7 | 5.9 | 3.7e-09 | -0.38 | 0.08 | 0.15 | FALSE |
| 5 | GTEx | Thyroid | CCDC152 | 0.10 | 0.07 | lasso | 4 | 0.04 | 4.2e-04 | 5.8 | 5.9 | 4.3e-09 | -0.58 | 0.74 | 0.11 | FALSE |
| 6 | ROSMAP | Brain Pre-frontal Cortex | SEPP1 | 0.18 | 0.19 | lasso | 11 | 0.21 | 1.3e-26 | 5.6 | -5.9 | 4.7e-09 | 0.56 | 1.00 | 0.00 | FALSE |
| 7 | YFS | Blood | CCDC152 | 0.07 | 0.06 | enet | 16 | 0.06 | 2.0e-19 | 5.8 | 6.2 | 4.7e-10 | -0.62 | 1.00 | 0.00 | FALSE |
| 8 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | CCDC152 | 0.06 | 0.06 | blup | 40 | 0.07 | 1.6e-08 | 5.6 | -6.8 | 8.8e-12 | 0.73 | 0.73 | 0.26 | FALSE |
| 9 | The Cancer Genome Atlas | Prostate Adenocarcinoma | CCDC152 | 0.15 | 0.12 | lasso | 6 | 0.12 | 1.0e-12 | 6.3 | -6.4 | 1.8e-10 | 0.58 | 1.00 | 0.00 | FALSE |
| 10 | The Cancer Genome Atlas | Prostate Adenocarcinoma | SEPP1 | 0.06 | 0.02 | blup | 38 | 0.04 | 5.2e-05 | 5.6 | -6.9 | 5.4e-12 | 0.76 | 0.23 | 0.69 | TRUE |