Hub : Genes

SEPP1

Models

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.0610	0.0220	1.3e-05	-0.002	0.038	0.019	0.034	0.008	7.1e-01	1.9e-05	2.1e-03	4.2e-05	2.8e-02
2	GTEx	Breast Mammary Tissue	0.1120	0.0610	9.1e-03	0.032	NA	0.018	NA	0.028	9.3e-03	NA	3.9e-02	NA	1.4e-02
3	GTEx	Breast Mammary Tissue (Female)	0.1526	0.0739	7.3e-03	-0.003	NA	0.017	NA	-0.009	4.0e-01	NA	1.0e-01	NA	7.2e-01
4	GTEx	Esophagus Mucosa	0.0710	0.0350	5.1e-03	0.042	NA	0.046	NA	-0.004	8.0e-04	NA	4.7e-04	NA	7.4e-01
5	ROSMAP	Brain Pre-frontal Cortex	0.1764	0.0378	0.0e+00	0.194	0.190	0.199	0.198	0.211	2.2e-24	6.7e-24	4.9e-25	7.4e-25	1.3e-26
6	TCGA	Breast Invasive Carcinoma	0.0142	0.0122	9.7e-03	0.005	0.007	0.012	NA	0.005	2.8e-02	1.2e-02	1.5e-03	NA	2.4e-02
7	TCGA	Lung Squamous Cell Carcinoma	0.1599	0.0659	8.6e-04	0.001	0.016	0.016	NA	0.005	2.3e-01	4.9e-03	5.1e-03	NA	7.0e-02
8	TCGA	Prostate Adenocarcinoma	0.0583	0.0339	4.2e-05	0.023	0.039	0.031	NA	0.038	1.6e-03	5.2e-05	2.9e-04	NA	7.4e-05

Trait associations

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8
Bipolar Disorder (2018)	0.4	0.6	2.0	-0.5	-0.7	0.2	1.4	0.8	0.7	1.0	0.3
Bipolar Disorder or Schizophrenia	0.1	0.3	1.2	-0.7	0.1	0.0	1.1	-0.2	0.7	-0.2	0.2
Depressed Affect (Nagel 2018)	0.7	1.5	3.0	1.7	1.2	1.0	-0.7	1.1	1.4	-0.4	1.6
Depression (Nagel 2018)	0.3	0.4	1.6	1.0	1.3	0.2	-0.0	-0.2	0.4	-0.6	0.1
Intelligence (Savage-Jansen 2018)	0.7	2.3	6.5	-1.6	-2.2	0.3	2.6	-0.5	-0.6	1.6	-1.1
Neuroticism (Nagel 2018)	0.2	0.5	1.3	1.1	-0.0	-0.4	-0.1	0.5	0.9	0.3	1.0
Schizophrenia (2018)	0.2	0.4	1.2	-0.6	0.6	-0.2	0.3	-0.9	0.4	-1.1	0.0
Schizophrenia vs Biploar Disorder	0.6	0.8	1.9	-0.2	-0.9	-1.4	1.3	-0.8	-1.0	-0.4	-0.4
Worry (Nagel 2018)	0.2	0.5	2.4	0.2	-0.9	-1.6	-0.6	-0.4	0.3	-0.3	0.5
Alzheimer’s Disease (in mother)	0.4	0.4	1.4	-0.1	-0.7	-1.2	0.3	-0.7	-0.7	-0.7	-0.3
Alzheimer’s Disease (in father)	1.2	1.3	6.6	-0.0	-0.6	-2.6	-0.5	0.7	1.1	-0.1	1.3
Alzheimer’s Disease (including proxy)	0.8	1.1	6.1	-0.1	-1.4	-2.5	-0.0	0.4	0.5	0.3	0.8
Crohns Disease (2017)	0.5	1.1	2.8	-1.7	-0.3	-1.5	1.4	-1.1	-0.2	-0.8	-0.2
Irritable Bowel Disease (IBD)	0.4	0.9	2.8	-1.2	-1.1	-1.3	1.7	-0.3	-0.1	-0.4	0.5
Ulcerative Colitis (UC)	0.3	0.7	1.9	0.1	-1.4	-0.2	1.1	0.8	0.2	0.7	0.9
Major Depression (MDD)	4.5	5.4	14.3	-0.7	0.3	-2.9	-0.5	-3.8	-2.3	-3.2	-2.1
Reaction Time	0.4	0.8	1.9	0.4	1.3	0.7	1.4	-0.9	-0.7	-0.5	-0.9
Verbal and Numeric Reasoning (VNR)	2.0	4.8	8.5	-2.2	-2.6	-0.4	2.9	-1.8	-2.3	1.7	-2.5
Breast Cancer	1.5	3.6	16.4	0.7	3.1	4.0	0.1	1.1	-0.5	-0.0	-0.5
Ovarian Cancer	0.2	0.3	1.5	1.2	0.6	0.1	-0.4	0.0	0.1	0.0	0.1
Prostate Cancer	1.5	2.0	12.8	0.6	0.1	0.2	-3.6	-0.9	-0.3	-1.5	0.0
Age at First Birth	0.6	0.9	2.7	0.3	-0.9	1.4	0.7	1.6	0.3	0.3	0.9
Bipolar Disorder (2011)	0.4	0.4	1.5	0.0	-0.5	-0.5	1.2	0.3	0.9	0.2	0.4
Body Mass Index (BMI) (2010)	0.5	0.6	4.2	0.1	-0.7	-2.0	-0.0	-0.4	0.4	-0.3	-0.2
Coronary Artery Disease (CAD)	1.6	1.9	4.0	1.7	0.3	1.0	-0.8	2.0	1.4	-1.4	1.6
Crohns Disease (2012)	0.9	1.4	3.3	-1.6	-0.3	-1.8	0.8	-1.4	-1.0	-0.2	-1.1
Mean Putamen Volume	0.8	0.9	5.4	1.2	0.4	-0.0	-2.3	0.2	0.3	0.3	0.3
Fasting Glucose	1.7	2.0	5.2	1.1	0.1	0.3	-2.0	2.3	1.5	-0.6	1.7
HbA1C	0.2	0.2	0.7	0.4	-0.9	-0.2	0.4	0.1	-0.1	0.8	-0.0
HDL Cholesterol	0.5	0.8	3.0	-1.7	-1.4	-0.1	1.0	-0.4	-0.3	0.2	-0.4
LDL Cholesterol	0.3	0.4	1.9	0.4	1.4	0.6	-1.0	0.3	-0.2	0.2	0.0
Lupus	0.6	0.9	3.1	0.1	-0.7	-1.8	-1.4	-0.2	-0.1	-1.2	0.5
Neuroticism (2016)	0.6	0.9	3.5	1.6	0.8	-0.2	-1.9	0.2	0.2	0.0	0.3
Primary Biliary Cirrhosis	1.0	1.4	5.3	-2.2	-0.8	-0.2	2.3	0.2	0.1	0.8	-0.0
Rheumatoid Arthritis	0.2	0.2	0.6	-0.4	0.4	0.2	-0.2	0.5	0.8	-0.3	0.7
Schizophrenia (2014)	0.3	0.6	1.1	-1.0	1.1	0.9	1.0	-0.5	0.3	-0.6	-0.2
Triglycerides	1.5	2.5	5.5	2.3	1.4	2.0	-1.1	1.7	1.6	0.6	1.3
Type 2 Diabetes (T2D) (2012)	0.6	0.6	1.2	0.6	-0.8	-0.8	-0.9	1.1	1.0	0.6	0.5
Ulcerative Colitis	1.0	1.4	3.4	-0.1	-1.8	-1.2	1.8	0.4	0.1	1.7	0.3
Blood Eosinophil Count	0.2	1.3	2.8	-0.3	-0.2	-1.7	1.2	-1.3	-1.3	0.2	-1.6
Blood Platelet Count	0.1	0.8	4.4	-0.9	0.1	-0.2	-0.6	-0.8	0.5	-2.1	0.5
Blood Red Count	0.6	5.8	16.7	4.1	1.9	2.3	0.0	3.0	2.4	1.3	2.1
Blood White Count	0.1	1.0	1.9	1.1	1.1	0.2	1.4	0.8	1.1	-0.7	1.0
Heel T-Score	2.1	17.0	39.9	5.6	1.7	6.3	0.5	5.3	2.8	4.5	2.1
BMI	1.3	7.5	20.3	1.1	1.1	-2.6	-0.1	-4.5	-3.7	-1.6	-3.7
Height	3.0	57.7	128.7	-7.6	-4.3	-4.2	5.7	-10.6	-8.8	4.1	-11.3
Waist Hip Ratio (WHR)	0.5	2.4	6.8	2.6	1.4	1.6	-1.2	1.8	1.1	-0.1	1.3
Systolic Blood Pressure	0.5	2.7	7.3	2.2	-0.1	-2.7	-2.4	-0.5	0.9	-1.4	0.8
Smoking Status	0.9	2.2	6.5	2.4	1.6	-0.0	-2.6	0.1	0.6	-1.5	0.6
Allergy or Eczema	1.4	3.6	10.3	-3.2	-1.4	-1.4	0.8	-2.7	-1.8	-1.1	-1.5
Cardiovascular Disease	0.4	1.2	5.2	1.1	0.1	-2.3	-0.9	-0.8	-0.8	0.4	-0.8
Hypothyroidism (self reported)	1.1	2.6	5.9	-0.8	0.9	-0.4	1.3	-2.3	-2.4	-0.1	-2.4
Respiratory disease	0.3	0.7	3.3	-0.0	0.7	-1.8	0.0	0.3	0.9	0.5	0.6
Type 2 Diabetes (T2D) (2018)	0.3	0.6	1.5	1.2	0.9	0.7	1.1	0.5	0.2	-0.7	0.5
Lung FEV1/FVC ratio	1.1	5.4	12.5	2.5	0.5	3.1	-0.9	3.5	2.2	0.5	2.8
Lung FVC	0.7	3.3	21.7	-0.2	0.8	4.7	-1.5	1.1	0.7	0.3	0.3
Neuroticism	0.1	0.3	1.1	1.0	0.3	-0.3	0.2	0.5	0.7	0.2	0.9
Chronotype (morning person)	1.9	4.3	8.8	3.0	1.3	1.8	-2.6	2.5	1.8	0.1	2.1
Hair Pigment	0.0	0.5	2.8	-0.3	0.1	0.7	1.7	0.6	0.2	-0.2	0.3
Tanning	0.0	0.6	1.3	-1.1	-0.7	1.1	-0.5	-0.6	-0.7	0.5	-0.7
Hand grip strength (left)	1.4	3.7	13.9	-1.2	0.2	-0.8	-1.6	-2.8	-1.5	-3.7	-1.0
Number of treatments/medications taken	0.6	1.1	2.5	-0.7	-0.4	-1.6	-1.6	-1.2	-0.9	0.4	-1.1
Average weekly spirits intake	1.3	1.6	3.5	-0.7	-0.3	-1.6	0.4	-1.6	-1.6	0.8	-1.9
Sensitivity / hurt feelings	0.3	0.5	1.8	0.7	0.5	0.5	1.4	0.2	-0.4	0.7	-0.2
Frequency of depressed mood in last 2 weeks	0.4	0.6	2.6	0.7	-0.6	-1.6	0.5	-0.3	0.0	1.0	-0.2
Hearing difficulty/problems: Yes	2.0	3.0	11.3	-0.2	1.6	3.4	2.3	0.9	-1.2	1.2	-1.2
Relative age of first facial hair	0.6	1.2	2.7	0.8	-1.2	-1.2	-1.7	0.5	0.5	-1.1	1.2
Other serious medical condition/disability diagnosed by doctor	0.6	0.8	1.8	-1.1	-0.9	-0.9	0.7	-0.7	-1.4	0.5	-0.8
Ever used hormone-replacement therapy (HRT)	1.7	2.1	7.1	-2.7	-2.0	-0.8	0.6	-0.9	-1.4	0.9	-1.2
Ever had hysterectomy (womb removed)	0.5	0.5	2.3	-1.5	-0.2	-0.1	0.6	-0.8	-0.5	0.1	-0.7
Systolic blood pressure, automated reading	0.7	1.9	9.8	0.5	-0.4	-1.7	-3.1	-0.9	-0.1	-1.1	-0.1
Eye problems/disorders: Diabetes related eye disease	0.7	0.8	2.8	-0.3	-1.7	-1.1	0.2	0.3	0.5	1.2	0.5
Angina	0.9	1.2	2.5	-1.6	-1.3	-0.9	1.4	-0.4	-0.5	1.3	-0.8
Medication for hormone replacement therapy	0.7	0.8	3.5	-0.2	-1.9	-1.1	0.2	-0.2	-0.3	1.2	-0.2
Vitamin and mineral supplements	0.7	0.9	3.2	1.8	0.0	0.4	-0.3	0.8	0.5	1.7	0.1
Supplements: Zinc	0.5	0.6	2.4	0.2	-0.4	0.5	1.1	0.3	-0.3	1.5	-0.7
Medication: Co-codamol	0.3	0.3	0.6	0.6	-0.0	-0.5	0.6	0.4	0.8	0.2	0.8
Medication: Metformin	0.7	1.0	2.2	1.5	0.7	1.3	0.9	1.3	0.6	0.5	0.5
Diabetes (father)	4.8	5.9	11.7	1.1	1.8	3.2	-1.6	3.4	2.9	-0.2	3.1
Diabetes (mother)	1.8	2.2	3.2	1.2	1.4	0.0	-1.7	-1.7	-1.8	-1.6	-1.6
Severe depression (siblings)	2.3	2.6	6.4	-0.2	-1.1	-2.5	-2.1	-1.3	-0.9	-2.5	0.2
Pack years adult smoking proportion	0.9	1.3	6.7	2.6	0.8	0.7	-0.9	1.1	0.4	0.0	0.5
Impedance of leg (right)	2.2	10.6	26.3	2.0	0.5	3.9	-3.1	5.1	3.5	1.4	3.9
Leg fat-free mass (left)	5.1	26.9	70.1	-3.7	-1.7	-5.3	2.9	-8.4	-6.2	-0.3	-7.3
Trunk fat percentage	0.2	1.0	2.5	1.6	-0.2	-1.5	-0.4	-1.0	-1.1	0.3	-0.8
Hand grip strength (right)	1.1	2.9	8.5	-1.2	-0.6	-1.9	-0.9	-2.6	-1.1	-2.9	-0.7
Townsend deprivation index at recruitment	0.6	0.8	2.6	0.2	-1.4	-1.6	-1.0	-0.5	0.4	-0.4	0.6
Current tobacco smoking	1.1	1.8	5.8	2.4	2.1	0.7	-0.8	1.0	0.7	-1.1	0.8
Average weekly fortified wine intake	0.2	0.3	0.7	0.4	0.6	-0.3	0.5	0.4	0.6	-0.8	0.5
Maternal smoking around birth	1.6	2.3	5.3	2.3	-0.4	-0.7	-1.8	1.6	1.4	1.7	1.3
Fed-up feelings	0.4	0.6	2.3	1.5	-0.2	-0.5	-0.7	0.1	0.8	-0.2	1.1
Frequency of unenthusiasm / disinterest in last 2 weeks	0.4	0.5	1.2	0.7	1.1	0.5	-0.8	0.5	0.7	-0.2	0.6
Relative age voice broke	0.8	1.2	5.0	-1.6	-0.3	-0.0	-0.7	-1.1	-0.3	-2.2	0.1
Taking other prescription medications	0.2	0.3	1.4	0.2	0.7	-0.1	-1.2	-0.2	-0.1	-0.5	-0.0
Age when periods started (menarche)	0.9	2.2	5.6	-1.6	-0.5	1.8	0.5	2.4	1.4	1.6	1.1
Bilateral oophorectomy (both ovaries removed)	0.4	0.5	1.4	-0.3	-0.0	-0.4	1.2	-0.4	-0.9	0.6	-1.1
Heel bone mineral density (BMD) T-score, automated (left)	1.8	4.1	12.8	1.9	0.1	3.0	1.2	2.4	0.6	3.6	-0.1
Tinnitus: Yes, but not now, but have in the past	1.1	1.2	4.2	0.9	-0.1	-0.6	-1.7	-0.2	0.3	-2.1	0.9
Qualifications: CSEs or equivalent	1.5	2.0	8.6	2.9	0.7	0.9	-0.9	1.2	1.5	0.7	1.1
Serious illness, injury or assault to yourself	0.5	0.6	2.5	-0.4	-0.5	0.0	1.6	0.2	-0.5	1.1	-0.4
High blood pressure	1.2	3.5	9.7	-0.7	-1.4	-3.1	-2.8	-2.0	-1.2	0.5	-1.5
Hayfever, allergic rhinitis or eczema	1.3	2.9	8.0	-2.8	-0.9	-1.4	0.1	-2.6	-1.4	-1.5	-1.1
Multivitamins +/- minerals	0.5	0.6	2.9	-0.8	-0.7	-0.3	1.7	-0.3	-0.7	0.0	-0.5
Stomach or abdominal pain in last month	1.7	2.1	4.0	-0.4	-1.5	-1.2	0.4	-1.5	-1.9	1.6	-2.0
Supplements: Glucosamine	0.6	0.8	4.7	0.3	0.3	2.2	0.5	0.8	0.5	-0.1	0.5
Diverticular disease/diverticulitis (self-reported)	0.5	0.7	2.0	0.6	-1.0	-0.1	0.5	-0.1	-1.4	0.9	-1.0
Medication: Atenolol	0.6	0.7	2.1	-0.7	0.1	0.1	1.0	-1.1	-0.9	0.4	-1.4
Medication: Levothyroxine sodium	0.5	0.9	2.3	-0.4	1.5	-0.9	0.8	-0.8	-1.1	-0.1	-1.1
Sitting height	3.1	22.2	59.4	-4.4	-2.0	-0.6	1.6	-7.2	-6.0	2.1	-7.7
Chronic bronchitis/emphysema (father)	1.3	1.5	5.8	2.4	1.5	1.2	1.2	1.2	-0.0	0.1	0.1
High blood pressure (mother)	1.2	1.7	3.7	0.1	0.4	-1.9	-1.5	-1.9	-1.5	-0.9	-1.3
Body mass index (BMI)	0.9	3.7	9.7	0.2	-0.2	-2.9	0.8	-3.1	-2.3	-1.3	-2.0
Impedance of leg (left)	2.2	10.8	25.0	2.5	1.3	4.1	-3.1	5.0	3.4	0.9	3.9
Leg predicted mass (left)	5.2	27.5	70.6	-3.8	-1.9	-5.4	3.0	-8.4	-6.3	-0.2	-7.3
Trunk fat mass	1.2	5.0	11.8	0.1	-0.7	-2.6	0.8	-3.4	-3.1	0.4	-3.2
Waist circumference	0.9	3.1	6.9	0.3	-0.5	-2.3	1.1	-2.6	-2.2	0.6	-2.6
Number of incorrect matches in round	0.4	0.7	4.0	-0.1	-0.1	-0.2	-2.0	0.7	0.6	0.1	0.8
Past tobacco smoking	0.4	0.7	3.5	-0.3	-0.6	0.4	1.9	0.3	-0.2	1.2	-0.2
Alcohol usually taken with meals	0.7	1.2	4.5	0.7	1.4	2.1	0.6	0.6	-0.4	1.1	-0.6
Nervous feelings	0.7	1.3	4.3	-0.8	-1.8	-2.1	0.3	-0.0	0.4	1.3	0.5
Frequency of tenseness / restlessness in last 2 weeks	0.4	0.6	1.5	1.1	0.8	-0.2	-1.2	0.2	0.4	-0.8	0.9
Hearing difficulty/problems with background noise	0.9	1.4	5.4	-0.7	0.4	1.1	1.4	0.3	-0.5	2.3	-1.2
Hair/balding pattern: Pattern 2	0.8	1.0	2.5	0.3	-0.6	0.6	-1.6	1.0	1.2	0.6	1.3
Had menopause	0.8	1.1	2.6	-1.5	-0.6	1.2	1.6	1.0	-0.5	0.7	-0.1
Had other major operations	1.2	1.5	3.2	-0.4	-0.7	-1.2	-1.0	-1.8	-1.5	-1.5	-1.2
Forced vital capacity (FVC)	1.0	3.9	11.1	-2.0	-0.5	0.6	-0.3	-3.1	-2.3	1.0	-3.3
Heel bone mineral density (BMD) T-score, automated (right)	1.6	3.7	13.9	1.7	-1.0	2.2	1.1	2.2	0.9	3.7	0.2
Ever unenthusiastic/disinterested for a whole week	0.3	0.3	0.6	-0.7	0.2	-0.6	-0.8	0.6	0.1	-0.3	0.8
Qualifications: None of the above	0.5	1.1	2.2	1.1	1.5	0.4	-1.3	1.0	0.8	-0.8	1.1
Financial difficulties in last 2 years	0.5	0.7	3.2	0.5	-0.7	-1.1	-1.8	-0.7	-0.1	0.4	0.1
Mouth/teeth dental problems	1.1	1.8	5.6	-1.7	-2.4	-1.9	0.1	-0.4	-0.0	1.4	-0.2
Heart attack	1.1	1.4	3.3	-0.2	-0.7	0.5	0.0	1.6	1.7	1.8	1.2
Allergy	0.4	0.8	3.3	1.8	0.5	1.3	-0.2	0.9	0.1	0.5	-0.0
Pain all over the body in last month	0.4	0.4	1.6	0.7	0.6	0.4	-0.7	-0.3	-0.3	-1.3	-0.0
Diabetes (self-reported)	0.2	0.3	1.0	0.1	-0.1	-0.1	1.0	0.7	0.6	-0.3	0.8
Hayfever/allergic rhinitis (self-reported)	1.1	1.5	5.0	-2.2	-0.6	-0.5	0.8	-1.4	-1.5	-0.8	-0.9
Medication: Ramipril	1.3	1.7	8.7	-0.3	-1.7	-3.0	-0.8	-0.6	-0.7	0.3	-0.1
Medication: Simvastatin	0.5	0.8	2.3	-0.2	-1.5	-1.5	-0.9	0.3	0.0	0.9	0.2
Fluid intelligence score	0.8	1.6	3.2	-1.1	-1.4	-0.3	1.2	-1.6	-1.5	0.6	-1.8
Illnesses of siblings	0.5	0.7	1.6	1.2	0.3	1.3	-0.3	1.0	-0.9	0.8	-0.3
Neuroticism score	0.2	0.4	1.7	1.3	1.0	0.3	-0.4	0.0	0.2	-0.1	0.3
Weight	3.5	17.2	44.5	-2.3	-1.3	-4.2	2.4	-6.7	-5.2	-0.0	-5.9
Impedance of arm (right)	2.4	11.2	26.6	2.4	0.5	3.9	-3.2	5.2	3.7	1.9	3.9
Arm fat percentage (right)	0.3	1.2	2.4	1.5	0.4	-1.2	-0.3	-1.3	-1.5	-0.8	-1.0
Trunk fat-free mass	7.0	40.2	98.1	-5.3	-2.2	-5.2	3.8	-9.9	-7.9	0.2	-9.3
Hip circumference	2.6	11.2	21.2	-2.0	-2.3	-4.2	2.3	-4.6	-4.0	1.1	-4.3
Time employed in main current job	0.4	0.4	1.2	0.6	-0.1	-0.3	0.0	-0.5	-1.1	0.6	-1.1
Alcohol intake versus 10 years previously	1.2	1.7	5.9	-0.5	-1.5	0.5	1.5	1.2	1.0	2.4	0.6
Father’s age at death	1.0	1.4	3.3	-1.8	-0.1	1.4	0.8	1.5	1.1	0.8	1.0
Worrier / anxious feelings	0.6	1.1	5.2	1.5	0.5	-0.1	-2.3	-0.5	-0.1	-0.7	0.0
Frequency of tiredness / lethargy in last 2 weeks	0.1	0.2	1.0	0.0	0.1	-1.0	-0.0	-0.6	-0.5	0.2	-0.4
Falls in the last year	0.7	0.9	2.2	-0.7	0.2	-0.9	-0.1	-1.2	-1.5	-0.5	-1.4
Hair/balding pattern: Pattern 3	1.3	1.9	4.9	-0.6	1.0	-0.5	-0.1	-1.9	-2.2	-0.7	-2.2
Number of live births	1.7	2.4	4.7	0.4	1.7	2.0	-0.7	1.8	2.2	-0.9	1.8
Forced expiratory volume in 1-second (FEV1)	0.5	1.6	3.6	-1.5	-0.1	1.3	-0.5	-1.8	-1.3	0.4	-1.9
Pulse rate	0.3	0.5	2.2	0.1	0.9	0.2	-0.5	-0.5	0.1	-1.5	0.1
Happiness	1.0	1.2	3.6	-1.9	-0.8	-1.1	-1.1	-0.7	-0.8	-1.3	-0.3
Noisy workplace	2.0	2.5	5.1	1.3	1.5	1.3	-2.3	1.9	1.6	-0.2	1.6
Qualifications: A levels/AS levels or equivalent	1.2	2.6	5.0	-1.6	-1.1	-0.5	2.2	-1.8	-1.6	1.2	-2.2
Serious illness, injury or assault of a close relative in last 2 years	1.9	2.2	4.5	-1.7	-1.2	-1.6	0.3	-1.7	-2.1	0.1	-1.7
Mouth/teeth dental problems: Dentures	1.6	2.8	6.7	2.6	2.5	2.4	-1.0	1.4	0.4	-0.3	0.4
Asthma	0.4	0.8	4.0	-0.3	-0.1	-2.0	0.7	0.2	0.3	1.3	0.3
Medication: Ibuprofen (e.g. Nurofen)	1.4	1.8	3.6	0.7	1.3	-1.0	-1.6	-1.9	-1.3	-1.1	-1.5
Medication: Cholesterol lowering	1.3	2.1	5.1	0.7	-1.8	-1.3	-1.1	1.6	0.8	2.3	1.1
Depression (self-reported)	0.8	0.9	2.5	0.9	-1.2	-1.6	-0.2	-0.2	-0.3	1.6	-0.3
Medication: Lansoprazole	1.4	1.6	3.0	-0.8	-1.7	-0.8	1.2	1.5	1.3	1.1	1.3
Prospective memory result	0.5	0.6	1.8	-0.7	-0.5	-0.3	0.1	-1.1	-1.4	-0.2	-0.9
Lung cancer (father)	0.6	0.7	2.7	0.7	1.7	1.1	-0.5	0.7	0.2	0.3	-0.1
Illnesses of mother	0.8	1.0	2.4	1.0	-0.2	0.6	-0.2	1.5	1.6	1.2	0.9
Forced expiratory volume in 1-second (FEV1), Best measure	0.6	2.1	5.0	-1.6	0.7	1.6	-0.8	-1.8	-1.3	0.6	-2.2
Pulse wave Arterial Stiffness index	0.1	0.1	0.4	-0.0	-0.3	0.6	0.0	0.2	0.2	0.2	-0.1
Impedance of arm (left)	2.6	11.9	29.5	2.6	0.3	3.4	-2.6	5.4	4.2	2.3	4.3
Arm fat mass (right)	1.3	5.2	13.5	0.1	-0.1	-2.5	0.9	-3.7	-3.2	-0.4	-3.3
Trunk predicted mass	7.1	40.5	98.6	-5.3	-2.1	-5.1	3.9	-9.9	-7.9	0.3	-9.4
Standing height	3.4	34.2	84.0	-5.5	-2.4	-3.2	3.8	-8.5	-7.1	2.7	-9.2
Length of working week for main job	2.5	2.8	7.2	-1.0	1.2	1.3	-0.3	-2.1	-2.7	-1.1	-2.2
Exposure to tobacco smoke at home	0.1	0.1	0.3	0.2	0.5	-0.2	0.5	-0.5	0.3	-0.4	-0.1
Breastfed as a baby	0.5	0.6	1.6	-1.3	-1.1	0.1	0.6	-0.2	-0.9	0.4	-0.5
Tense / ‘highly strung’	0.3	0.5	2.4	1.0	-0.1	0.1	-1.5	0.2	0.1	0.9	0.1
Seen doctor (GP) for nerves, anxiety, tension or depression	0.6	0.9	1.5	-1.0	-0.7	-1.2	-0.3	-1.2	-1.0	0.4	-1.1
Hair/balding pattern: Pattern 4	0.6	1.4	4.9	-0.8	-0.2	-2.2	1.1	-1.5	-1.0	-0.6	-1.1
Birth weight of first child	1.7	3.2	9.4	-2.1	-0.0	-1.0	3.1	-1.7	-1.9	-0.6	-1.9
Peak expiratory flow (PEF)	0.6	1.3	2.3	-1.4	-0.1	0.3	-1.3	-1.5	-1.5	-0.9	-1.2
Pulse wave reflection index	0.1	0.2	0.7	0.1	-0.1	0.2	0.8	0.4	0.1	-0.6	0.2
Ever highly irritable/argumentative for 2 days	0.9	1.1	3.4	0.5	0.4	-0.0	-1.1	0.3	1.1	-1.8	1.5
Loud music exposure frequency	0.5	0.6	1.6	0.0	0.6	1.1	-1.3	-1.0	-0.3	-0.5	-0.4
Qualifications: O levels/GCSEs or equivalent	1.2	1.9	8.3	-0.3	-0.1	1.1	2.9	-0.4	-1.2	1.3	-1.6
Mouth/teeth dental problems: Bleeding gums	0.9	1.1	2.9	0.3	0.4	1.7	0.8	1.2	1.0	-0.9	1.4
Blood clot in the leg (DVT)	1.3	1.7	4.0	0.7	0.7	1.8	-1.1	2.0	1.4	0.1	1.7
Medication: Paracetamol	0.3	0.4	1.8	0.2	-0.2	-0.8	-1.3	0.1	-0.2	0.9	-0.3
Headache pain in last month	0.3	0.6	1.2	-0.2	1.1	0.2	-1.1	0.1	-1.0	0.5	-0.9
Medication for cholesterol, blood pressure or diabetes	1.1	1.8	6.7	-0.6	1.2	2.6	2.0	0.4	0.8	-0.9	0.6
Glaucoma (self-reported)	0.6	0.7	2.0	-0.2	0.1	1.0	0.7	0.6	1.4	1.3	0.6
Gout (self-reported)	0.8	1.1	3.4	0.3	-1.4	-1.8	-1.7	-0.5	-0.2	0.3	0.1
Hypothyroidism/myxoedema (self-reported)	0.5	1.0	2.1	-0.7	0.6	-1.2	1.4	-1.1	-1.2	-0.5	-0.7
Medication: Amlodipine	1.4	2.0	5.7	-0.7	1.7	0.2	-0.5	-1.7	-1.5	-2.4	-1.3
Medication: Ventolin 100micrograms inhaler	1.1	1.4	5.2	0.2	-1.3	-1.9	-0.4	0.1	-0.1	2.3	-0.5
Birth weight	1.0	2.2	5.5	-2.3	0.9	1.0	2.3	-0.8	-1.3	-1.1	-1.2
Chronic bronchitis/emphysema (mother)	1.9	2.2	4.6	1.4	0.7	1.1	-0.9	2.1	2.0	1.0	1.9
High blood pressure (siblings)	2.1	3.0	9.2	-0.8	-1.4	-3.0	-0.5	-2.6	-1.4	-0.2	-1.7
Forced vital capacity (FVC), Best measure	0.9	3.4	10.0	-1.9	0.4	1.4	-0.0	-2.6	-1.8	1.2	-3.2
Body fat percentage	0.2	0.9	2.8	1.7	0.3	-1.2	-0.7	-0.9	-1.0	-0.3	-0.6
Leg fat percentage (right)	0.2	0.7	1.5	1.2	0.6	-0.8	-0.7	-0.8	-1.1	-1.0	-0.3
Arm fat-free mass (right)	6.4	32.8	81.4	-4.3	-1.5	-5.2	3.7	-9.0	-7.1	-0.3	-8.3
Exposure to tobacco smoke outside home	0.6	0.8	2.7	-0.3	1.6	1.4	0.5	0.2	-0.4	-1.2	-0.1
Comparative body size at age 10	0.7	1.8	7.7	-0.5	-0.5	-1.5	2.8	-1.2	-1.2	-0.9	-0.7
Number of full brothers	0.7	0.9	4.6	-2.1	-0.7	-0.9	0.5	-0.9	-0.3	-0.2	-0.4
Worry too long after embarrassment	0.3	0.5	2.9	0.8	0.1	0.4	1.7	0.1	0.4	-0.3	0.5
Seen a psychiatrist for nerves, anxiety, tension or depression	0.4	0.6	1.9	-0.4	-0.4	-1.4	-0.5	-1.1	-0.6	-0.6	-0.4
Wheeze or whistling in the chest in last year	0.2	0.3	0.8	-0.0	-0.5	-0.9	0.2	0.5	0.5	0.5	0.8
Number of children fathered	0.5	0.6	3.7	-0.4	0.5	0.4	1.9	0.3	-0.2	-0.2	0.0
Reason for reducing amount of alcohol drunk: Health precaution	1.2	1.4	2.5	-1.0	-1.2	-1.6	-1.3	-1.6	-0.7	-0.9	-0.8
Age at first live birth	2.1	3.7	7.7	-2.0	-2.8	-2.0	1.8	-1.7	-1.3	2.0	-1.5
Pulse wave peak to peak time	0.3	0.4	1.0	-0.4	-0.1	-1.0	0.5	-0.9	-0.7	0.0	-0.6
Health satisfaction	1.0	1.3	3.1	0.7	-1.0	-0.0	-0.5	1.8	1.5	1.0	1.5
Shortness of breath walking on level ground	0.7	0.8	2.1	-1.1	-0.7	-0.7	-1.0	-1.5	-0.5	-0.3	-0.8
Qualifications: College or University degree	1.0	3.1	6.2	-2.2	-1.8	-1.9	0.9	-2.5	-1.4	0.5	-1.9
Eye problems/disorders: None of the above	0.2	0.2	0.5	-0.7	-0.6	-0.7	0.6	-0.4	-0.2	-0.1	-0.1
Mouth/teeth dental problems: Loose teeth	0.3	0.4	1.9	1.4	0.2	-0.4	-0.0	-0.2	0.3	0.9	-0.3
Emphysema/chronic bronchitis	3.8	4.3	11.6	1.5	0.3	1.1	-0.0	3.0	3.4	0.5	3.2
Medication for pain relief, constipation, heartburn	0.8	1.4	8.2	-0.5	-0.7	0.7	2.9	1.0	0.4	0.5	0.4
Neck or shoulder pain in last month	0.1	0.2	0.6	0.1	-0.3	-0.5	-0.3	0.3	-0.5	0.8	-0.4
Medication: Blood pressure	1.6	2.8	6.3	0.2	-0.4	-2.5	-1.7	-1.8	-1.8	1.0	-2.3
Angina (self-reported)	0.8	1.0	2.9	-1.7	-1.2	-0.6	1.3	-0.1	-0.3	1.1	-0.5
Migraine (self-reported)	0.7	0.9	3.0	0.2	0.6	-0.8	-1.7	-0.8	-0.9	-1.2	-0.4
Medication: Ibuprofen	2.4	2.8	5.7	0.8	1.5	-0.6	-2.2	-2.4	-1.8	-1.3	-1.9
Medication: Allopurinol	0.4	0.5	1.8	0.5	-1.1	-1.3	-0.4	-0.2	-0.8	0.5	-0.1
Medication: Omeprazole	1.1	1.3	3.9	0.9	0.0	-0.7	-1.0	-1.1	-2.0	0.4	-1.6
Medication: Seretide 50 evohaler	0.5	0.5	1.2	-0.3	0.8	-0.3	-1.0	-0.2	1.1	-1.0	0.5
Mean time to correctly identify matches	0.3	0.5	0.9	-0.6	0.9	0.4	0.8	-1.0	-0.6	0.1	-0.9
Heart disease (mother)	0.3	0.4	1.1	-0.4	-0.6	-0.8	-1.0	-0.5	-0.3	-0.6	0.2
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.3	0.3	1.0	-0.1	0.6	0.1	-0.8	-0.1	1.0	-0.3	0.4
Whole body fat mass	1.3	5.6	14.1	-0.1	-0.6	-2.8	0.7	-3.7	-3.3	-0.0	-3.4
Leg fat mass (right)	1.4	5.6	15.1	-0.4	-0.1	-2.5	0.4	-3.9	-3.4	-0.8	-3.2
Arm predicted mass (right)	6.2	31.5	81.7	-4.1	-1.2	-4.9	3.2	-9.0	-7.0	-0.5	-8.3
Pulse rate, automated reading	0.3	1.1	2.9	-0.5	1.7	1.0	1.5	-0.0	0.4	-1.5	0.3
Alcohol intake frequency.	1.1	2.5	5.9	0.2	-0.7	0.0	0.3	2.3	2.4	1.6	2.4
Comparative height size at age 10	2.8	15.2	47.5	-1.1	0.5	-1.5	2.7	-5.9	-5.1	1.7	-6.9
Number of full sisters	1.5	1.9	5.2	-2.0	-2.3	-1.1	1.5	-0.7	-0.8	0.7	-0.6
Suffer from ‘nerves’	0.4	0.7	2.6	-0.5	-1.2	-1.6	0.2	-0.2	0.6	-0.0	0.8
Overall health rating	0.7	1.5	6.8	-0.1	-0.9	-2.6	0.0	-1.5	-1.1	-0.0	-0.8
Chest pain or discomfort	0.6	0.9	2.8	0.6	0.2	-0.1	0.0	-1.3	-1.3	0.6	-1.7
Had major operations	0.2	0.2	0.9	0.9	-0.1	0.2	-0.5	0.7	-0.1	-0.1	0.6
Age at last live birth	1.8	2.7	7.2	-2.7	-2.0	-1.5	1.1	-1.4	-0.7	1.6	-1.2
Family relationship satisfaction	1.1	1.3	4.5	-2.1	-1.0	-0.8	-1.0	-1.2	-0.8	-0.9	-0.6
Leg pain on walking	0.9	1.1	4.7	0.6	0.6	2.2	1.5	0.9	-0.3	0.7	-0.1
Qualifications: NVQ or HND or HNC or equivalent	0.6	0.8	1.9	0.1	0.0	0.9	-0.7	1.2	1.2	0.2	1.4
Commuting to job workplace: Car/motor vehicle	1.8	2.0	6.1	1.0	2.3	2.5	-1.1	0.4	0.7	-1.2	0.4
Illness, injury, bereavement, stress in last 2 years	0.3	0.3	0.9	0.5	0.0	-0.0	-0.4	-0.9	-0.5	-0.9	-0.5
Medication: Aspirin	0.4	0.5	1.5	-0.4	0.7	0.6	-1.2	-0.6	0.2	-0.9	-0.1
Supplements: Vitamin C	0.9	1.1	2.8	-0.0	0.4	0.3	-1.0	-1.2	-1.7	-1.4	-1.1
Knee pain experienced in last month	0.3	0.5	1.5	1.2	1.2	0.6	-0.7	-0.1	-0.3	-0.6	-0.2
Hypertension (Self-reported)	1.4	3.8	11.2	-0.8	-1.5	-3.4	-2.2	-2.2	-1.6	0.8	-1.9
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.3	0.4	1.0	1.0	-0.2	-0.7	-0.9	0.7	-0.5	0.3	0.1
Illnesses of father: Heart disease	0.7	1.0	2.7	-0.9	-0.4	-0.2	-0.0	0.1	1.6	-1.4	1.4
Illnesses of siblings: Diabetes	2.3	2.9	6.4	0.6	1.7	1.1	1.2	1.7	2.5	-1.5	2.4
Smoking status: Previous	0.4	0.6	3.0	0.0	0.0	-0.4	-1.7	0.2	0.6	-0.7	0.7
Forced expiratory volume in 1-second (FEV1), predicted	2.4	5.0	12.0	-2.7	-1.4	-1.8	0.6	-3.5	-2.6	0.2	-2.9
Whole body fat-free mass	6.5	37.3	93.7	-4.8	-1.9	-5.5	3.7	-9.7	-7.5	-0.1	-8.8
Leg fat-free mass (right)	5.3	28.3	73.8	-3.8	-1.4	-5.3	3.3	-8.6	-6.4	-0.5	-7.5
Arm fat percentage (left)	0.3	1.1	2.5	1.6	0.3	-1.5	-0.1	-1.1	-1.2	-0.5	-0.8
Average weekly red wine intake	1.0	1.4	4.6	-1.6	-2.2	-1.2	0.1	-1.3	-0.9	-0.1	-0.7
Handedness (chirality/laterality): Left-handed	0.7	0.8	2.8	-1.7	-0.8	1.4	0.5	0.8	0.3	0.2	0.7
Mood swings	0.2	0.3	1.0	0.9	0.7	-0.2	-1.0	-0.3	-0.2	-0.5	0.1
Loneliness, isolation	1.2	1.6	3.3	1.7	1.1	0.0	-0.8	1.4	1.7	-0.5	1.8
Long-standing illness, disability or infirmity	0.3	0.5	1.5	-0.6	0.5	0.1	-0.1	-1.2	-1.0	-0.2	-1.0
Ever had bowel cancer screening	1.1	1.3	6.6	-2.6	-0.9	-0.3	0.5	-0.5	-0.9	1.1	-0.7
Diabetes diagnosed by doctor	0.5	0.8	1.4	0.6	0.9	1.2	0.6	1.1	0.9	-0.6	0.9
Ever had stillbirth, spontaneous miscarriage or termination	0.9	1.0	5.8	0.0	-0.2	-0.5	-2.4	-0.1	-0.4	1.0	-0.7
Friendships satisfaction	0.5	0.7	3.0	0.7	-0.2	-0.1	-1.7	1.0	0.5	0.3	0.6
Qualifications: nursing, teaching	1.0	1.6	4.3	-1.3	-0.7	0.0	0.6	-2.1	-1.7	-0.6	-1.6
Commuting to job workplace: Walk	1.0	1.0	2.9	1.5	-0.2	-0.7	-1.7	0.1	-0.7	1.2	-0.7
Eye problems/disorders: Cataract	1.0	1.1	3.3	0.5	1.3	0.9	-1.6	0.1	-0.5	-1.8	0.1
Mouth/teeth dental problems: Mouth ulcers	0.4	0.7	1.7	0.9	1.3	0.5	-0.7	-0.8	-0.7	-0.2	-1.0
Medication for cholesterol	0.5	0.7	2.8	0.8	1.7	0.9	0.1	0.6	0.5	-0.7	0.6
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.4	0.5	2.4	-0.6	0.2	0.0	-1.6	-0.7	-0.7	-0.2	-0.6
Back pain experienced in last month	0.6	0.9	6.4	0.4	-0.3	0.0	0.0	-0.3	0.1	2.5	-0.6
Mineral and other dietary supplements	0.6	0.8	4.0	0.6	-0.3	-2.0	-1.1	-0.5	0.2	0.1	0.0
Breast cancer (self-reported)	0.6	0.7	2.4	-0.7	-0.1	-0.4	-0.9	-0.6	-1.1	-1.5	-0.3
Asthma (self-reported)	0.4	0.8	4.8	-0.3	-0.1	-2.2	0.5	-0.1	0.0	1.0	0.0
Osteoporosis (self-reported)	0.4	0.5	2.0	-0.3	0.5	0.4	-1.1	0.5	1.4	-0.0	0.7
Osteoarthritis (self-reported)	0.4	0.5	1.5	1.2	-0.1	0.9	-0.5	-0.1	-0.3	0.9	-0.5
Medication: Aspirin	0.5	0.6	2.0	-0.5	0.9	1.4	-0.8	-0.6	0.3	-0.9	-0.1
Medication: Gliclazide	0.1	0.1	0.4	-0.6	0.1	-0.0	0.1	-0.5	0.1	-0.0	-0.2
Illnesses of father: None of the above (group 1)	1.4	1.7	3.9	0.6	0.2	0.2	-1.9	-1.1	-1.8	1.2	-2.0
Smoking status: Current	1.2	1.9	7.2	2.7	2.2	0.8	-0.7	0.8	0.5	-1.1	0.5
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.9	1.9	5.4	0.3	0.3	2.3	-1.4	1.7	1.5	0.4	1.4
Whole body water mass	6.5	36.9	92.9	-4.7	-1.9	-5.4	3.7	-9.6	-7.5	-0.1	-8.8
Leg predicted mass (right)	5.3	28.1	73.4	-3.7	-1.4	-5.3	3.2	-8.6	-6.4	-0.4	-7.5
Arm fat mass (left)	1.3	5.3	13.8	0.1	-0.1	-2.7	1.0	-3.7	-3.1	-0.7	-3.2
Number of self-reported non-cancer illnesses	1.2	2.1	4.3	-0.0	-0.9	-1.1	-1.4	-1.4	-1.8	2.1	-1.8
Average weekly champagne plus white wine intake	1.5	2.1	4.7	-1.4	-0.5	-0.8	1.3	-1.7	-2.0	0.5	-2.2
Miserableness	0.1	0.1	0.4	0.2	-0.0	-0.6	0.6	-0.4	-0.2	0.4	-0.2
Guilty feelings	0.4	0.6	1.4	0.5	-0.4	-0.7	1.0	-1.0	-1.2	-0.0	-1.0
Wears glasses or contact lenses	1.1	1.3	3.0	-1.7	-1.0	0.1	-0.3	0.3	-1.5	1.6	-0.9
Ever taken oral contraceptive pill	1.3	1.4	3.1	0.5	1.3	1.6	0.7	1.2	1.8	-0.3	1.3
Hearing aid user	0.6	0.7	2.6	1.6	0.3	-0.0	-0.4	1.1	0.3	1.1	0.2
Mother’s age at death	1.5	1.9	6.1	-1.8	0.2	1.1	2.5	-0.2	-1.2	1.2	-1.2
Financial situation satisfaction	0.4	0.5	1.4	-0.2	-0.6	-0.0	-1.0	0.5	0.7	-0.7	1.2
Tinnitus: Yes, now most or all of the time	0.5	0.6	2.7	-0.4	0.8	0.8	1.6	-0.3	-0.3	-0.3	-0.4
Commuting to job workplace: Public transport	1.4	1.6	4.3	0.3	-2.1	-0.5	2.0	0.6	-0.9	1.8	-0.3
Eye problems/disorders: Glaucoma	0.9	1.1	2.9	1.0	0.2	0.6	0.4	1.4	1.7	1.0	1.2
Medication: Blood pressure	0.2	0.4	0.7	-0.9	0.4	0.1	-0.8	-0.7	-0.5	-0.1	-0.8
Pain type(s) experienced in last month: Hip pain	0.6	0.7	1.7	1.1	0.8	1.3	0.4	0.9	0.9	0.4	0.5
Supplements: Fish oil (including cod liver oil)	0.9	1.2	6.0	-0.3	0.5	2.4	0.9	1.2	0.5	-0.2	0.7
High cholesterol (Self-reported)	1.4	2.5	5.9	1.8	-0.6	0.5	-1.0	2.4	1.8	1.4	2.0
Medication: Bendroflumethiazide	0.4	0.6	2.0	0.3	1.0	-0.7	-0.3	0.2	0.7	-1.4	0.6
Medication: Paracetamol	0.3	0.4	1.7	0.1	0.3	-0.3	-1.3	0.1	-0.7	0.8	-0.7
Medication: Lisinopril	0.7	0.9	3.1	-0.9	-1.6	-1.7	0.1	-0.3	0.4	0.9	-0.0
Medication: Atorvastatin	0.6	0.7	3.9	0.5	0.4	2.0	0.5	0.7	-0.0	1.0	-0.2
Illnesses of father: High blood pressure	1.7	2.1	6.3	-0.5	-2.5	-2.0	0.6	-1.7	-1.4	0.2	-1.0
Alcohol drinker status: Never	1.1	1.4	6.1	-2.5	-0.9	-1.0	-0.5	-1.2	-0.3	-1.1	-0.3
Ever smoked	0.5	0.9	1.8	-0.7	0.8	0.0	-1.3	-1.3	-0.6	-1.4	-0.7
Basal metabolic rate	5.9	32.9	84.5	-4.1	-1.6	-5.3	3.4	-9.2	-7.1	-0.2	-8.3
Leg fat percentage (left)	0.3	1.0	2.2	1.5	1.0	-0.8	-0.6	-0.8	-1.1	-1.2	-0.4
Arm fat-free mass (left)	6.3	32.2	83.0	-3.9	-1.1	-4.5	3.4	-9.1	-7.3	-0.7	-8.5
Number of operations (self-reported)	0.6	0.9	2.7	-0.8	-0.3	-1.6	-0.3	-0.3	-1.3	-1.3	-0.1
Average weekly beer plus cider intake	0.2	0.3	1.0	-0.1	0.0	0.2	-0.6	-0.8	-0.2	-1.0	-0.2
Irritability	0.5	0.9	3.6	0.8	0.8	0.5	-1.9	0.4	0.7	1.0	0.3
Risk taking	1.1	1.6	5.7	1.4	1.8	0.6	-2.4	1.0	0.1	-0.1	0.1
Ever had prostate specific antigen (PSA) test	1.0	1.2	5.1	0.8	-0.1	-0.5	-2.3	0.2	0.7	-1.4	1.0
Fractured/broken bones in last 5 years	3.9	5.0	10.1	-2.0	-2.1	-3.2	-0.9	-3.1	-2.6	-0.4	-2.1
Age started oral contraceptive pill	0.4	0.5	1.5	-0.5	-1.2	0.9	-0.0	0.6	0.3	-0.3	0.9
Diastolic blood pressure, automated reading	0.5	1.6	4.4	-0.1	-1.3	-2.1	-1.0	-1.3	-1.5	-0.6	-1.1
Ever depressed for a whole week	0.3	0.3	0.8	-0.8	-0.1	-0.5	0.3	-0.9	-0.6	-0.2	-0.5
Unable to work because of sickness or disability	0.9	1.2	5.0	1.5	-0.2	-0.8	-2.2	0.1	0.9	0.7	0.4
Commuting to job workplace: Cycle	0.4	0.5	1.9	-0.6	-0.1	-0.5	0.6	-0.0	1.4	0.7	0.5
Myopia	1.1	1.6	2.9	-1.4	-1.1	-0.8	0.7	-1.7	-1.7	0.4	-1.5
Vascular/heart problems diagnosed by doctor	1.0	2.8	8.3	0.9	1.4	2.4	2.9	1.5	1.0	-0.7	1.2
Cholesterol lowering medication	0.2	0.3	1.0	-1.0	-0.0	0.9	0.3	-0.5	-0.3	-0.1	-0.6
Medication: Omeprazole (e.g. Zanprol)	1.7	2.1	4.7	0.5	0.4	-0.5	-1.9	-1.8	-2.2	-0.1	-2.1
Pain experienced in last month	0.1	0.2	1.0	-0.0	-0.0	0.5	0.6	-0.0	0.5	-1.0	0.3
Supplements: Calcium	1.0	1.1	3.8	-1.9	-1.1	0.9	0.8	-0.7	-1.1	0.2	-1.0
Basal cell carcinoma (self-reported)	1.4	1.6	7.8	0.0	1.5	0.4	-2.8	-0.1	1.0	-1.1	0.5
Heart attack/myocardial infarction (self-reported)	1.1	1.4	3.2	-0.1	-0.5	0.8	-0.0	1.6	1.8	1.6	1.3
Deep venous thrombosis (DVT) (self-reported)	1.3	1.6	4.2	0.1	0.7	1.8	-0.6	2.1	1.4	0.0	1.7
Heart disease (siblings)	0.5	0.6	2.2	-1.5	-0.2	-0.5	-0.2	-0.9	0.8	-0.9	0.4
Alcohol drinker status: Previous	1.6	1.8	5.6	0.7	-0.3	-0.0	0.1	1.8	2.3	0.4	2.4
Pack years of smoking	0.5	0.8	4.4	2.1	0.5	0.7	-0.7	0.8	-0.1	0.2	0.1
Impedance of whole body	2.9	14.7	36.5	2.9	0.9	4.4	-3.0	6.0	4.3	1.8	4.6
Leg fat mass (left)	1.4	5.4	14.3	-0.1	0.1	-2.5	0.5	-3.8	-3.3	-0.8	-3.2
Arm predicted mass (left)	6.3	31.9	83.0	-3.9	-0.9	-4.3	3.5	-9.1	-7.3	-0.6	-8.5