[Hub]/) : Traits : Comparative height size at age 10 : ← →

chr5:53,702,093-56,917,974

Best TWAS P=4.27e-18 · Best GWAS P=1.96e-17 conditioned to 0.0649

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	DDX4	0.08	0.07	bslmm	390	0.08	1.7e-10	8.1	-8.2	1.6e-16	-0.85	0.03	0.97	FALSE
2	GTEx	Adipose Subcutaneous	SETD9	0.15	0.14	lasso	10	0.16	3.0e-13	-4.9	5.2	1.6e-07	0.00	0.80	0.20	FALSE
3	GTEx	Adipose Subcutaneous	SLC38A9	0.11	0.00	enet	24	0.00	6.5e-01	8.3	-5.2	2.0e-07	-0.49	0.04	0.21	FALSE
4	GTEx	Adipose Visceral Omentum	SETD9	0.16	0.20	lasso	8	0.16	6.8e-09	-4.5	5.4	5.4e-08	0.00	0.50	0.50	FALSE
5	GTEx	Adrenal Gland	SETD9	0.39	0.29	lasso	8	0.35	1.6e-13	-4.5	5.2	2.3e-07	-0.04	0.81	0.19	FALSE
6	GTEx	Brain Cerebellum	SLC38A9	0.26	0.13	lasso	4	0.10	7.4e-04	8.3	8.3	1.4e-16	0.84	0.02	0.95	FALSE
7	GTEx	Brain Hippocampus	GZMA	0.32	0.00	lasso	6	0.02	1.3e-01	4.9	6.3	2.2e-10	0.37	0.08	0.19	FALSE
8	GTEx	Brain Putamen basal ganglia	SETD9	0.23	0.15	lasso	3	0.14	2.9e-04	-4.8	5.3	1.0e-07	-0.06	0.07	0.69	FALSE
9	GTEx	Breast Mammary Tissue	SETD9	0.30	0.38	lasso	4	0.38	8.2e-21	-4.5	5.1	2.8e-07	0.00	0.93	0.07	FALSE
10	GTEx	Breast Mammary Tissue (Female)	SETD9	0.21	0.12	lasso	11	0.16	1.4e-05	-5.2	5.7	1.5e-08	0.00	0.05	0.91	FALSE
11	GTEx	Breast Mammary Tissue (Female)	GPX8	0.04	0.00	lasso	2	0.03	5.0e-02	8.1	-7.4	1.9e-13	-0.89	0.05	0.25	FALSE
12	GTEx	Cells Transformed fibroblasts	SETD9	0.31	0.42	lasso	6	0.47	5.7e-39	-4.5	5.3	1.1e-07	-0.02	0.92	0.08	FALSE
13	GTEx	Colon Sigmoid	SETD9	0.49	0.49	lasso	14	0.53	7.9e-22	-4.1	5.2	2.1e-07	0.00	0.95	0.04	FALSE
14	GTEx	Colon Transverse	SETD9	0.47	0.42	lasso	10	0.43	4.0e-22	-4.5	5.3	1.4e-07	-0.02	0.91	0.09	FALSE
15	GTEx	Esophagus Mucosa	SETD9	0.47	0.55	lasso	9	0.58	1.3e-47	-4.5	5.2	1.6e-07	-0.02	0.93	0.07	FALSE
16	GTEx	Skin Sun Exposed Lower leg	SETD9	0.40	0.44	lasso	15	0.46	1.8e-42	-4.5	5.2	2.3e-07	-0.01	0.93	0.07	FALSE
17	GTEx	Stomach	SETD9	0.35	0.31	lasso	8	0.38	1.9e-19	-4.5	5.4	8.0e-08	-0.03	0.76	0.24	FALSE
18	GTEx	Uterus	SETD9	0.31	0.15	lasso	8	0.19	1.2e-04	-4.5	5.4	7.1e-08	0.01	0.22	0.27	FALSE
19	ROSMAP	Brain Pre-frontal Cortex	DDX4	0.07	0.08	lasso	2	0.07	1.5e-09	8.1	-8.2	2.0e-16	-0.79	0.07	0.93	FALSE
20	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	C5orf35	0.21	0.28	lasso	7	0.31	8.0e-27	-4.5	5.2	1.5e-07	-0.01	0.87	0.13	FALSE
21	The Cancer Genome Atlas	Breast Invasive Carcinoma	C5orf35	0.29	0.42	lasso	8	0.46	3.0e-107	-4.5	5.5	3.8e-08	-0.02	0.87	0.13	FALSE
22	The Cancer Genome Atlas	Breast Invasive Carcinoma	PPAP2A	0.06	0.03	lasso	1	0.03	1.1e-06	8.3	-8.3	7.8e-17	-0.78	0.00	1.00	FALSE
23	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	C5orf35	0.24	0.35	lasso	11	0.37	1.9e-43	-4.5	5.4	5.9e-08	-0.02	0.87	0.13	FALSE
24	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	C5orf35	0.35	0.46	lasso	5	0.48	7.8e-62	-4.5	5.3	1.1e-07	-0.02	0.87	0.13	FALSE
25	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	C5orf35	0.27	0.30	lasso	6	0.36	1.4e-21	-4.5	5.7	1.5e-08	-0.02	0.80	0.20	FALSE
26	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	SLC38A9	0.04	0.02	enet	7	0.03	6.6e-03	8.1	7.6	3.0e-14	0.86	0.02	0.75	FALSE
27	The Cancer Genome Atlas	Brain Lower Grade Glioma	C5orf35	0.28	0.39	lasso	5	0.40	2.1e-48	-4.5	5.1	3.1e-07	-0.02	0.87	0.13	FALSE
28	The Cancer Genome Atlas	Lung Adenocarcinoma	C5orf35	0.42	0.45	enet	17	0.50	3.2e-67	-4.5	5.4	6.8e-08	0.00	0.87	0.13	FALSE
29	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	C5orf35	0.21	0.29	lasso	11	0.33	1.3e-38	-4.5	5.1	2.8e-07	-0.03	0.87	0.13	FALSE
30	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	C5orf35	0.33	0.35	enet	22	0.36	4.9e-16	-4.5	5.2	1.6e-07	-0.02	0.84	0.16	FALSE
31	The Cancer Genome Atlas	Prostate Adenocarcinoma	C5orf35	0.44	0.58	lasso	9	0.60	1.4e-78	-4.5	5.1	2.7e-07	-0.01	0.87	0.13	FALSE
32	The Cancer Genome Atlas	Skin Cutaneous Melanoma	C5orf35	0.23	0.08	blup	58	0.17	2.5e-05	-5.7	5.9	3.0e-09	-0.05	0.03	0.95	TRUE
33	The Cancer Genome Atlas	Stomach Adenocarcinoma	C5orf35	0.32	0.40	enet	19	0.44	4.8e-35	-4.5	5.2	2.2e-07	-0.02	0.89	0.11	FALSE
34	The Cancer Genome Atlas	Thyroid Carcinoma	C5orf35	0.46	0.61	lasso	14	0.63	1.5e-79	-4.5	5.1	2.9e-07	-0.02	0.87	0.13	FALSE
35	The Cancer Genome Atlas	Thyroid Carcinoma	SLC38A9	0.03	0.04	blup	52	0.04	2.0e-04	8.4	8.7	4.3e-18	0.95	0.02	0.98	TRUE
36	The Cancer Genome Atlas	Uterine Corpus Endometrial Carcinoma	C5orf35	0.38	0.05	blup	58	0.06	7.0e-03	-4.6	5.6	2.4e-08	-0.02	0.04	0.69	FALSE