TWAS hub - CCDC152

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.1820	0.0580	4.6e-05	0.079	0.019	0.068	NA	0.072	6.4e-10	1.7e-03	1.1e-08	NA	4.3e-09
2	GTEx	Adipose Subcutaneous	0.0940	0.0370	1.1e-03	0.036	NA	0.012	NA	0.022	6.3e-04	NA	3.5e-02	NA	6.4e-03
3	GTEx	Adipose Visceral Omentum	0.0890	0.0420	6.5e-03	0.058	NA	0.039	NA	0.046	5.9e-04	NA	4.1e-03	NA	1.9e-03
4	GTEx	Artery Aorta	0.3120	0.0600	3.6e-13	0.243	NA	0.221	NA	0.238	1.3e-13	NA	2.3e-12	NA	2.5e-13
5	GTEx	Artery Coronary	0.1970	0.0840	3.5e-03	0.133	NA	0.099	NA	0.120	3.1e-05	NA	3.2e-04	NA	7.7e-05
6	GTEx	Artery Tibial	0.2174	0.0497	2.8e-12	0.172	NA	0.185	NA	0.182	2.0e-13	NA	1.8e-14	NA	3.2e-14
7	GTEx	Esophagus Muscularis	0.1250	0.0440	2.2e-04	0.094	NA	0.096	NA	0.103	2.6e-06	NA	2.0e-06	NA	7.9e-07
8	GTEx	Nerve Tibial	0.1605	0.0616	9.4e-05	0.058	NA	0.063	NA	0.060	6.0e-05	NA	2.9e-05	NA	4.8e-05
9	GTEx	Testis	0.1660	0.0700	2.0e-03	-0.006	NA	0.100	NA	-0.005	7.4e-01	NA	3.3e-05	NA	5.8e-01
10	GTEx	Thyroid	0.0980	0.0450	5.2e-03	0.066	NA	0.018	NA	0.041	8.6e-06	NA	1.3e-02	NA	4.2e-04
11	ROSMAP	Brain Pre-frontal Cortex	0.1957	0.0515	1.3e-08	0.094	0.067	0.076	0.093	0.093	4.8e-12	5.9e-09	4.9e-10	5.2e-12	5.2e-12
12	YFS	Blood	0.0693	0.0186	1.1e-16	0.065	0.055	0.062	NA	0.058	2.6e-20	1.8e-17	2.0e-19	NA	2.2e-18
13	TCGA	Breast Invasive Carcinoma	0.1376	0.0742	9.9e-05	0.019	0.027	0.018	NA	0.016	6.6e-05	2.5e-06	1.2e-04	NA	2.3e-04
14	TCGA	Kidney Renal Clear Cell Carcinoma	0.0561	0.0314	1.7e-07	0.058	0.072	0.064	NA	0.068	3.6e-07	1.6e-08	9.9e-08	NA	4.2e-08
15	TCGA	Kidney Renal Papillary Cell Carcinoma	0.1120	0.0810	1.2e-03	0.019	0.039	0.045	NA	0.031	2.9e-02	2.8e-03	1.3e-03	NA	6.5e-03
16	TCGA	Lung Squamous Cell Carcinoma	0.2245	0.1156	1.1e-03	0.006	0.011	0.005	NA	0.000	6.3e-02	1.7e-02	7.6e-02	NA	2.7e-01
17	TCGA	Prostate Adenocarcinoma	0.1457	0.0764	3.3e-10	0.124	0.098	0.116	NA	0.122	6.5e-13	1.9e-10	3.8e-12	NA	1.0e-12

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17
Trunk predicted mass	10.9	62.2	106.1	4.0	10.0	9.4	9.1	9.9	8.1	8.7	6.4	-1.1	9.9	6.1	10.3	-5.5	-10.0	-4.4	-1.1	-9.7
Trunk fat-free mass	10.8	61.7	105.4	4.1	10.0	9.4	9.1	9.9	8.0	8.6	6.3	-1.0	9.9	6.1	10.3	-5.5	-10.0	-4.4	-1.1	-9.7
Whole body fat-free mass	10.2	58.0	99.0	3.9	9.8	9.1	8.9	9.6	7.6	8.3	6.4	-0.6	9.7	5.8	9.9	-5.1	-9.6	-4.3	-1.5	-9.2
Whole body water mass	10.1	57.6	98.4	3.9	9.8	9.1	8.8	9.6	7.6	8.3	6.3	-0.7	9.6	5.8	9.9	-5.1	-9.6	-4.3	-1.4	-9.2
Arm fat-free mass (left)	10.1	51.2	87.0	3.2	9.2	8.5	8.4	9.1	7.0	7.9	6.2	-0.6	9.1	5.0	9.3	-5.3	-9.0	-4.2	-1.6	-8.8
Arm predicted mass (left)	10.1	51.2	87.4	3.2	9.2	8.5	8.4	9.1	7.1	7.9	6.1	-0.8	9.1	4.9	9.3	-5.2	-9.0	-4.2	-1.4	-8.8
Arm fat-free mass (right)	9.7	49.6	85.4	3.2	9.1	8.5	8.2	9.0	7.0	7.7	6.1	-0.3	9.0	4.9	9.2	-4.8	-9.0	-3.9	-1.2	-8.7
Arm predicted mass (right)	9.6	49.3	84.2	2.8	9.0	8.3	8.3	8.9	7.1	7.8	6.1	-0.4	8.9	4.5	9.2	-4.8	-8.9	-4.2	-1.2	-8.8
Major Depression (MDD)	9.4	11.4	18.2	2.7	4.1	3.9	4.3	4.0	3.1	3.2	3.4	0.3	4.1	3.1	3.7	-2.7	-3.2	-2.8	-3.5	-3.2
Basal metabolic rate	9.3	51.6	88.2	3.5	9.3	8.6	8.5	9.1	7.0	7.9	6.1	-0.4	9.2	5.1	9.4	-4.9	-9.1	-4.2	-1.6	-8.7
Leg fat-free mass (right)	8.3	44.5	75.9	3.3	8.7	8.0	7.9	8.5	6.6	7.3	5.7	-0.3	8.6	4.8	8.7	-4.3	-8.4	-3.9	-1.8	-8.0
Leg predicted mass (right)	8.3	44.5	75.9	3.4	8.7	8.0	7.8	8.5	6.6	7.2	5.7	-0.3	8.5	4.8	8.7	-4.2	-8.4	-3.9	-1.7	-8.0
Leg fat-free mass (left)	8.1	42.7	73.1	3.5	8.5	7.8	7.7	8.3	6.4	7.2	5.6	-0.1	8.4	5.0	8.6	-4.2	-8.1	-3.8	-1.9	-7.7
Leg predicted mass (left)	8.1	43.0	73.6	3.4	8.5	7.8	7.7	8.4	6.4	7.2	5.6	-0.1	8.4	5.0	8.6	-4.2	-8.2	-3.8	-1.9	-7.7
Diabetes (father)	6.3	7.8	12.1	-0.7	-3.4	-3.2	-3.2	-3.4	-2.8	-3.2	-3.1	-0.5	-3.3	-1.3	-3.5	2.8	3.4	1.9	0.3	3.4
Emphysema/chronic bronchitis	6.0	6.8	12.8	-0.1	-2.8	-2.9	-2.7	-2.9	-2.9	-2.9	-2.5	-1.4	-3.0	-0.5	-3.0	3.4	3.6	2.6	-0.4	3.1
Weight	5.2	25.4	44.9	1.6	6.7	6.0	6.2	6.5	4.4	5.7	4.4	0.1	6.5	2.7	6.7	-3.5	-6.3	-3.0	-1.5	-6.1
Fractured/broken bones in last 5 years	5.0	6.5	9.6	-0.8	3.1	3.0	3.1	3.0	2.5	3.1	2.4	1.8	3.0	0.6	3.1	-2.6	-2.7	-1.9	-1.3	-3.1
Sitting height	4.8	34.2	61.2	3.7	7.3	7.1	6.2	7.3	6.1	6.4	4.2	-1.7	7.2	5.6	7.8	-3.2	-7.8	-2.0	1.1	-7.2
Standing height	4.7	47.0	89.2	4.7	8.6	8.1	7.0	8.5	7.3	7.1	5.2	-1.7	8.5	6.5	9.1	-3.7	-9.4	-2.3	2.0	-8.6
Impedance of whole body	4.4	22.2	37.0	-1.7	-6.1	-5.8	-5.9	-5.9	-4.4	-5.3	-3.5	0.8	-6.0	-2.9	-6.0	3.6	5.4	3.5	2.7	5.6
Height	3.9	76.0	137.1	7.3	10.9	10.4	8.8	10.8	9.0	8.6	6.4	-3.5	10.8	9.5	11.6	-4.1	-11.7	-1.4	2.3	-10.6
Comparative height size at age 10	3.9	21.5	46.6	2.8	5.8	5.1	4.9	5.9	3.8	4.9	3.1	-1.5	5.9	3.5	6.2	-2.5	-6.8	-1.8	2.4	-6.4
Impedance of arm (left)	3.8	17.7	29.9	-1.3	-5.5	-5.2	-5.3	-5.3	-3.7	-4.7	-3.2	0.5	-5.3	-2.5	-5.3	3.5	4.8	2.9	2.5	5.2
Medication: Ibuprofen	3.6	4.3	11.1	-0.5	2.3	1.8	2.3	2.2	3.3	2.3	2.5	1.7	2.2	0.1	2.2	-1.8	-2.3	-2.2	-0.8	-2.3
Forced expiratory volume in 1-second (FEV1), predicted	3.6	7.4	12.4	1.5	3.5	3.2	3.0	3.4	3.3	2.8	2.7	0.0	3.4	2.3	3.4	-1.8	-3.4	-0.8	-0.0	-3.3
High blood pressure (siblings)	3.4	4.8	7.8	0.9	2.7	2.2	2.7	2.6	2.3	2.6	2.8	0.6	2.5	1.6	2.6	-1.6	-2.2	-2.2	-1.1	-2.4
Impedance of leg (right)	3.3	15.9	27.1	-1.9	-5.2	-4.9	-4.9	-5.1	-3.8	-4.3	-3.0	1.2	-5.1	-2.7	-5.1	2.5	4.8	2.8	2.2	4.6
Impedance of leg (left)	3.2	15.7	26.2	-2.3	-5.1	-4.8	-4.9	-5.0	-3.8	-4.4	-2.7	1.4	-5.0	-3.1	-5.0	2.6	4.6	2.8	2.1	4.3
Impedance of arm (right)	3.2	15.0	25.9	-0.8	-5.1	-4.9	-4.9	-5.0	-3.2	-4.4	-3.1	0.5	-5.0	-1.8	-5.0	2.8	4.6	2.7	2.0	4.9
Length of working week for main job	3.2	3.5	10.0	-1.4	1.8	2.0	2.1	1.9	2.2	2.5	1.4	-1.1	1.8	-0.4	1.9	-3.2	-1.8	-1.3	0.0	-2.4
Coronary Artery Disease (CAD)	2.9	3.5	7.2	-0.6	-2.1	-2.0	-2.0	-2.0	-2.5	-2.1	-2.1	0.3	-1.8	-1.1	-2.0	1.5	2.0	2.7	-0.0	2.3
Hip circumference	2.9	12.3	22.7	1.3	4.6	4.1	4.3	4.6	2.8	3.8	3.1	0.4	4.6	2.0	4.8	-2.3	-4.6	-2.0	-0.7	-4.4
Fasting Glucose	2.7	3.2	6.1	-1.0	-2.2	-2.5	-2.1	-2.1	-1.8	-2.0	-1.5	0.2	-2.3	-1.3	-2.1	1.4	2.2	1.3	-0.4	1.9
Heel T-Score	2.6	20.7	30.6	0.1	-5.3	-5.1	-5.5	-5.1	-5.5	-5.4	-5.0	-1.9	-5.1	-2.1	-4.9	3.9	3.8	5.2	4.3	4.8
Chronic bronchitis/emphysema (mother)	2.6	3.0	6.2	0.1	-2.0	-2.3	-1.9	-2.0	-1.4	-1.8	-0.3	-0.6	-2.1	-0.3	-1.9	2.1	2.4	1.8	0.7	2.5
Hand grip strength (left)	2.4	6.3	10.3	1.0	3.0	3.0	3.1	2.8	2.9	2.5	1.9	1.3	2.8	2.1	2.6	-2.2	-2.1	-2.2	-3.2	-2.6
High blood pressure (mother)	2.4	3.4	9.1	-2.1	1.5	1.3	1.8	1.5	1.9	2.1	1.5	2.0	1.4	-1.6	1.4	-2.6	-1.5	-3.0	-0.6	-2.2
Hair/balding pattern: Pattern 3	2.4	3.6	8.4	-2.0	1.5	1.5	1.8	1.8	1.6	2.5	2.1	1.5	1.7	-1.3	1.8	-2.9	-1.9	-2.3	0.5	-2.4
Medication: Ibuprofen (e.g. Nurofen)	2.4	3.1	9.2	0.0	1.9	1.4	2.0	1.8	3.0	1.9	2.3	0.9	1.8	0.5	1.8	-1.4	-1.7	-2.2	-1.0	-1.8
High cholesterol (Self-reported)	2.4	4.3	9.1	-0.6	-2.4	-2.5	-2.2	-2.4	-3.0	-2.2	-1.7	-0.3	-2.4	-1.1	-2.3	1.6	2.6	2.2	0.5	2.6
Alcohol drinker status: Previous	2.4	2.7	4.9	0.6	-1.8	-1.9	-1.9	-2.0	-1.5	-2.2	-1.2	-0.2	-2.0	0.3	-1.9	1.9	2.2	1.5	-0.0	2.2
Medication: Omeprazole (e.g. Zanprol)	2.3	2.8	6.6	-1.8	1.5	1.2	1.5	1.6	1.8	2.2	1.5	1.9	1.5	-1.3	1.6	-2.6	-1.7	-1.3	0.8	-2.1
Serious illness, injury or assault of a close relative in last 2 years	2.2	2.5	5.3	-1.1	1.4	1.4	1.4	1.5	1.2	1.6	1.5	2.3	1.4	-0.8	1.5	-2.3	-2.0	-1.8	0.0	-2.2
Leg fat mass (right)	2.2	8.5	14.6	-0.1	3.8	3.3	3.8	3.8	2.0	3.4	2.9	1.2	3.8	0.4	3.8	-2.6	-3.3	-1.9	-1.7	-3.4
Illnesses of siblings: Diabetes	2.2	2.7	7.5	1.4	-1.4	-1.2	-1.5	-1.5	-1.5	-2.0	-1.3	-1.8	-1.5	1.1	-1.7	2.7	2.0	1.8	-0.7	1.9
Qualifications: nursing, teaching	2.2	3.4	6.6	-1.6	1.8	1.7	2.1	1.8	1.6	2.6	2.1	-0.1	1.8	-0.7	1.9	-2.5	-1.6	-2.4	-1.1	-2.3
Hayfever, allergic rhinitis or eczema	2.1	4.6	7.5	1.3	2.7	2.7	2.5	2.6	2.3	2.0	2.2	0.9	2.6	1.8	2.4	-1.0	-2.4	-1.5	-2.4	-1.9
Leg fat mass (left)	2.1	8.0	13.6	-0.1	3.7	3.2	3.7	3.7	1.9	3.2	2.9	1.2	3.6	0.3	3.7	-2.5	-3.3	-1.8	-1.6	-3.4
BMI	2.0	11.8	19.8	-0.6	4.3	3.7	4.5	4.2	2.4	4.0	3.6	1.8	4.2	-0.3	4.2	-3.4	-3.9	-3.0	-2.1	-4.2
Severe depression (siblings)	2.0	2.2	10.9	0.0	1.4	1.0	1.8	1.3	0.6	1.1	1.5	2.0	1.4	0.7	1.0	-1.4	-0.7	-1.7	-3.3	-1.4
Hand grip strength (right)	2.0	5.5	9.7	0.8	2.8	2.7	3.0	2.6	2.7	2.3	1.9	1.4	2.7	1.7	2.4	-1.7	-2.0	-2.4	-3.1	-2.3
Heel bone mineral density (BMD) T-score, automated (left)	2.0	4.6	7.7	0.4	-2.4	-2.2	-2.8	-2.2	-2.4	-2.4	-2.3	-1.9	-2.3	-0.6	-1.9	1.9	1.4	2.6	2.8	2.2
Noisy workplace	2.0	2.4	5.0	0.6	-1.8	-1.9	-1.9	-1.8	-0.8	-2.1	-0.5	-0.5	-1.7	0.1	-1.7	2.2	1.8	2.0	0.6	1.9
Forced vital capacity (FVC)	1.9	7.2	12.1	2.7	3.3	3.2	2.5	3.2	3.2	2.4	1.4	-1.9	3.2	3.5	3.5	-0.4	-3.4	0.8	1.3	-2.9
Arm fat mass (right)	1.9	7.6	13.2	0.4	3.6	3.0	3.6	3.6	1.9	3.2	2.6	0.6	3.6	0.7	3.6	-2.5	-3.3	-1.9	-1.4	-3.2
Arm fat mass (left)	1.9	8.0	14.2	0.6	3.7	3.1	3.8	3.7	2.0	3.3	2.7	0.6	3.7	0.9	3.7	-2.4	-3.3	-1.9	-1.7	-3.2
Hearing aid user	1.9	2.1	6.9	-2.0	-1.4	-1.8	-1.4	-1.3	-0.3	-0.8	-1.1	2.0	-1.5	-2.6	-1.3	-0.2	0.6	-0.5	2.3	0.7
Deep venous thrombosis (DVT) (self-reported)	1.9	2.4	4.5	-0.9	-2.0	-1.6	-1.8	-1.9	-1.1	-1.4	-2.0	-0.3	-1.9	-1.3	-1.9	1.0	2.1	0.9	0.2	2.0
Age at First Birth	1.8	2.6	8.2	0.9	-1.7	-1.6	-1.9	-1.7	-1.9	-2.0	-1.9	-0.1	-1.7	0.2	-1.7	0.7	1.6	2.9	0.5	1.9
Lung FEV1/FVC ratio	1.8	9.4	16.4	-1.4	-3.6	-4.0	-3.3	-3.7	-3.5	-3.5	-2.8	-0.3	-3.7	-2.2	-3.8	1.8	3.8	2.9	-0.1	3.4
Chronotype (morning person)	1.8	4.2	6.7	-1.8	-2.5	-2.6	-2.2	-2.5	-1.8	-2.0	-1.9	2.3	-2.5	-2.3	-2.5	1.0	2.2	0.3	0.8	1.9
Maternal smoking around birth	1.8	2.5	5.2	-0.8	-1.8	-2.3	-1.7	-1.8	-1.9	-1.6	-1.6	1.3	-1.9	-1.2	-1.7	1.4	1.7	1.1	1.2	1.4
Had other major operations	1.8	2.2	3.9	0.2	1.7	1.6	1.7	1.6	1.5	1.5	1.7	0.6	1.6	0.7	1.5	-1.7	-1.6	-1.4	-1.1	-2.0
Mouth/teeth dental problems: Bleeding gums	1.8	2.3	6.7	0.1	-1.2	-1.0	-1.4	-1.4	-1.8	-2.0	-2.6	-2.0	-1.3	-0.2	-1.4	1.6	1.3	2.3	-0.4	1.4
Qualifications: College or University degree	1.8	5.7	8.5	2.1	2.7	2.9	2.5	2.7	2.6	2.5	2.3	-0.0	2.7	2.9	2.8	-1.6	-2.7	-2.3	-0.8	-2.4
Medication: Blood pressure	1.8	3.1	6.5	-0.3	1.7	1.1	1.7	1.9	2.0	1.9	1.6	2.6	1.7	-0.3	1.9	-1.9	-2.2	-2.5	0.5	-1.9
Whole body fat mass	1.8	7.6	13.5	0.0	3.7	3.0	3.6	3.7	1.8	3.2	2.7	1.1	3.6	0.4	3.7	-2.4	-3.4	-1.7	-1.4	-3.3
Heart attack/myocardial infarction (self-reported)	1.8	2.4	7.2	1.5	-1.3	-1.1	-1.6	-1.4	-1.3	-1.9	-1.5	-1.1	-1.4	1.1	-1.3	2.7	1.4	2.2	0.8	1.6
Allergy or Eczema	1.7	4.4	7.5	0.1	2.6	2.7	2.5	2.5	2.2	2.1	2.1	0.7	2.6	0.8	2.4	-1.3	-2.5	-1.7	-2.1	-2.2
Chronic bronchitis/emphysema (father)	1.7	1.9	6.0	0.1	-1.1	-1.1	-1.3	-1.1	-2.2	-1.8	-2.5	-1.6	-1.1	-0.6	-1.1	0.9	0.8	2.3	0.7	1.0
Heart attack	1.7	2.2	6.3	1.3	-1.3	-1.1	-1.6	-1.4	-1.4	-1.8	-1.6	-0.9	-1.4	0.9	-1.3	2.5	1.4	2.1	1.0	1.6
Blood clot in the leg (DVT)	1.7	2.2	4.2	-0.8	-2.0	-1.6	-1.7	-1.8	-0.9	-1.4	-1.8	-0.2	-1.9	-1.2	-1.8	1.0	2.0	0.6	0.2	2.0
Reason for reducing amount of alcohol drunk: Health precaution	1.7	2.0	3.0	0.7	1.7	1.7	1.5	1.6	1.4	1.5	1.7	1.7	1.6	0.9	1.6	-0.7	-1.4	-1.3	-1.2	-1.4
Shortness of breath walking on level ground	1.7	2.1	4.5	1.3	1.7	1.5	1.7	1.6	2.1	1.5	1.4	-0.3	1.6	1.9	1.7	-0.5	-1.2	-1.1	-1.2	-1.1
Medication: Omeprazole	1.7	2.0	5.4	-2.3	0.8	0.4	0.8	0.9	1.2	1.4	0.9	2.1	0.8	-2.1	0.9	-2.2	-1.3	-0.8	1.3	-1.7
Average weekly champagne plus white wine intake	1.7	2.3	5.6	0.5	1.7	1.9	1.6	1.9	1.5	1.6	1.1	-0.5	1.9	0.7	1.9	-1.4	-2.4	-0.6	0.6	-2.1
Eye problems/disorders: Glaucoma	1.7	2.0	5.2	-0.7	-1.6	-1.3	-1.8	-1.6	-0.7	-1.5	-2.3	-0.9	-1.6	-1.1	-1.5	1.9	1.0	0.6	1.5	1.2
Average weekly spirits intake	1.6	2.0	3.3	0.8	1.7	1.5	1.6	1.7	1.7	1.7	1.8	0.4	1.6	0.8	1.8	-1.3	-1.6	-0.8	0.2	-1.6
Stomach or abdominal pain in last month	1.6	2.0	3.7	-1.4	1.2	1.4	1.2	1.3	1.5	1.5	1.8	-0.1	1.3	-0.8	1.5	-1.6	-1.9	-1.6	0.7	-1.9
Health satisfaction	1.6	2.1	4.0	0.5	-1.6	-1.4	-1.7	-1.7	-1.8	-1.6	-0.3	-0.7	-1.6	0.4	-1.5	1.5	1.9	1.8	0.2	2.0
Alcohol intake frequency.	1.6	3.7	6.8	-0.1	-2.3	-2.2	-2.2	-2.3	-1.8	-2.1	-0.9	-1.4	-2.4	-0.3	-2.3	2.2	2.6	1.6	0.5	2.6
Hypertension (Self-reported)	1.6	4.5	12.7	-1.1	1.9	1.5	2.0	1.8	1.7	2.4	2.7	3.6	1.8	-0.7	2.0	-2.4	-2.0	-3.3	-0.2	-2.2
Triglycerides	1.5	2.4	4.4	-1.7	-1.8	-2.1	-1.6	-1.8	-1.3	-1.3	-1.5	0.9	-1.8	-2.0	-1.8	1.5	1.7	0.6	1.0	1.4
High blood pressure	1.5	4.2	14.1	-1.0	1.8	1.3	1.9	1.7	1.7	2.2	2.8	3.8	1.6	-0.4	1.9	-2.1	-1.7	-3.4	-0.6	-2.0
Trunk fat mass	1.5	6.4	11.6	0.0	3.4	2.7	3.3	3.4	1.6	2.9	2.5	1.0	3.3	0.3	3.4	-2.0	-3.2	-1.5	-0.9	-3.0
Heel bone mineral density (BMD) T-score, automated (right)	1.5	3.4	5.9	-0.1	-2.2	-1.9	-2.4	-2.1	-2.3	-1.9	-2.2	-1.3	-2.1	-0.8	-1.8	1.7	1.4	1.5	2.2	2.0
Father’s age at death	1.5	2.1	3.4	1.7	-1.3	-0.9	-1.5	-1.3	-0.8	-1.6	-1.7	-1.6	-1.3	1.5	-1.2	1.7	1.2	1.7	0.8	1.8
Mouth/teeth dental problems: Dentures	1.5	2.5	5.7	-1.9	-1.6	-1.9	-1.4	-1.6	-1.5	-1.4	-1.8	-1.9	-1.6	-2.4	-1.6	0.4	1.5	1.3	0.5	1.4
Illnesses of father: High blood pressure	1.5	1.9	3.2	0.8	1.8	1.5	1.6	1.7	1.1	1.2	1.2	0.3	1.7	1.5	1.8	-1.0	-1.5	-0.3	-1.3	-1.5
Myopia	1.5	2.2	3.6	0.7	1.7	1.9	1.7	1.8	1.2	1.5	1.0	-0.5	1.8	1.4	1.8	-1.4	-1.8	-1.2	-0.9	-1.7
Lupus	1.4	2.1	16.6	-2.7	-0.1	-0.2	0.1	0.1	-0.9	0.5	0.8	4.1	-0.2	-2.5	-0.1	-0.7	0.1	-1.3	-0.8	-0.6
Hypothyroidism (self reported)	1.4	3.1	5.2	-1.3	2.0	2.1	1.9	1.9	2.0	2.1	0.7	-0.4	1.9	-0.7	2.0	-2.3	-2.2	-1.9	-0.0	-2.3
Medication: Metformin	1.4	2.0	5.1	1.7	-1.1	-1.0	-1.4	-1.1	-2.0	-1.7	-1.2	-2.1	-1.1	1.3	-1.1	1.1	1.1	2.3	0.7	1.4
Relative age voice broke	1.4	2.2	11.5	0.9	1.4	1.5	1.7	1.2	1.4	1.2	1.4	-1.0	1.3	1.6	1.1	-1.4	-0.5	-1.6	-3.4	-0.9
Number of live births	1.4	2.0	4.3	0.4	-1.5	-1.4	-1.5	-1.6	-0.8	-1.4	-1.6	-1.5	-1.5	-0.1	-1.6	1.7	2.0	0.8	-0.2	2.1
Medication: Cholesterol lowering	1.4	2.2	5.2	-0.2	-1.6	-1.8	-1.5	-1.5	-2.3	-1.8	-1.5	0.3	-1.5	-0.8	-1.4	1.5	1.5	1.7	0.4	1.7
Medication: Amlodipine	1.4	2.0	3.7	-0.3	1.6	1.4	1.7	1.5	1.5	1.5	0.7	0.8	1.5	-0.1	1.4	-1.8	-1.6	-1.9	-1.0	-1.8
Forced vital capacity (FVC), Best measure	1.4	5.2	8.7	2.2	2.6	2.7	1.9	2.6	2.9	2.0	0.8	-2.4	2.6	2.8	2.9	-0.0	-3.0	0.8	1.9	-2.4
Loneliness, isolation	1.4	1.9	3.8	-1.6	-1.6	-1.8	-1.3	-1.7	-1.0	-1.5	-0.6	0.3	-1.7	-2.0	-1.8	1.2	1.8	0.3	-0.1	1.2
Ovarian Cancer	1.3	1.7	9.4	-3.0	-0.6	-0.7	-0.4	-0.6	-0.5	0.0	-0.6	2.2	-0.6	-3.1	-0.5	-0.5	0.0	-1.3	1.2	-0.4
Age when periods started (menarche)	1.3	3.0	6.0	0.0	-2.3	-1.9	-2.5	-2.2	-0.6	-1.7	-1.0	-2.2	-2.3	-0.2	-2.0	1.2	2.0	1.4	1.4	2.0
Body mass index (BMI)	1.3	5.5	10.8	-0.4	3.1	2.6	3.3	3.0	1.3	2.7	2.2	0.8	3.0	-0.1	2.9	-2.0	-2.3	-2.0	-2.5	-2.5
Alcohol intake versus 10 years previously	1.3	1.9	4.3	-1.2	-1.5	-1.6	-1.5	-1.5	-1.7	-1.2	-0.9	-0.3	-1.6	-1.6	-1.3	1.1	1.1	1.2	2.1	1.0
Diabetes diagnosed by doctor	1.3	2.2	7.9	1.8	-0.8	-0.5	-1.0	-0.8	-2.4	-1.4	-1.4	-1.8	-0.8	1.6	-0.9	1.4	1.3	2.8	-0.3	1.6
Illnesses of father: None of the above (group 1)	1.3	1.6	4.0	-0.9	0.7	0.4	0.8	0.9	1.8	1.4	0.6	1.4	0.8	-0.9	0.9	-2.0	-1.6	-1.8	1.5	-1.3
Alzheimer’s Disease (including proxy)	1.2	1.8	17.1	-1.6	-0.7	-0.9	-0.6	-0.7	-0.0	-0.1	0.7	4.1	-0.7	-2.0	-0.7	-0.3	0.3	-1.6	0.7	0.2
Hearing difficulty/problems: Yes	1.2	1.9	11.9	-0.1	-1.2	-1.0	-1.6	-1.0	-0.8	-1.2	-0.9	-1.8	-1.0	-0.5	-0.7	0.1	0.1	2.4	3.5	0.5
Diabetes (mother)	1.2	1.6	2.7	-0.5	1.5	1.1	1.4	1.5	1.4	1.4	0.3	1.3	1.5	-0.4	1.4	-1.6	-1.5	-0.9	-0.8	-1.6
Had menopause	1.2	1.5	4.0	-1.3	-1.3	-0.7	-1.5	-1.1	-1.6	-1.2	-2.0	-1.2	-1.1	-0.8	-0.9	0.2	0.8	1.9	0.9	0.8
Qualifications: A levels/AS levels or equivalent	1.2	2.7	5.1	0.8	1.8	1.9	1.6	1.9	1.6	2.0	1.2	-0.6	1.9	1.3	2.0	-1.2	-2.3	-1.6	0.7	-2.0
Birth weight of first child	1.2	2.3	7.0	1.5	1.8	1.6	1.4	1.6	1.7	1.1	0.3	-2.6	1.6	1.4	1.6	-1.1	-1.7	0.3	0.0	-1.7
Qualifications: NVQ or HND or HNC or equivalent	1.2	1.4	3.2	0.6	-1.1	-0.8	-1.2	-1.2	-1.2	-1.4	-1.5	-0.5	-1.2	0.4	-1.2	1.3	1.5	1.6	-0.3	1.8
Average weekly red wine intake	1.2	1.8	4.7	1.7	1.5	1.6	1.3	1.4	1.7	1.0	0.7	-1.3	1.4	2.2	1.4	-0.9	-1.2	-0.5	-0.9	-1.1
Forced expiratory volume in 1-second (FEV1), predicted percentage	1.2	2.5	4.6	-0.3	-1.8	-1.6	-1.8	-1.9	-0.8	-1.6	-1.9	-1.1	-1.8	-0.6	-1.8	1.7	2.0	1.9	0.6	2.1
Ever taken oral contraceptive pill	1.2	1.4	3.5	-0.4	-1.2	-1.3	-1.3	-1.3	-1.0	-1.4	-1.0	-1.3	-1.2	-0.6	-1.4	1.9	1.1	0.8	0.7	1.3
Alcohol drinker status: Never	1.2	1.4	4.7	0.3	1.1	1.6	1.3	1.2	1.0	1.3	1.1	-1.0	1.2	1.2	1.0	-0.7	-0.6	-1.2	-2.2	-0.8
Alzheimer’s Disease (in mother)	1.1	1.3	7.4	-1.6	0.5	0.2	0.5	0.5	0.9	0.6	1.2	2.7	0.5	-1.5	0.4	-1.0	-0.9	-1.4	0.3	-1.1
Verbal and Numeric Reasoning (VNR)	1.1	2.7	7.6	1.8	1.9	2.3	1.2	2.0	0.7	1.2	0.6	-0.5	2.0	2.2	2.2	-0.8	-2.8	0.0	1.2	-1.8
Blood Red Count	1.1	10.2	19.8	-1.3	-3.1	-3.5	-3.3	-3.1	-4.1	-3.4	-4.5	-0.2	-3.1	-2.7	-3.1	3.3	3.0	4.4	2.5	3.2
Illnesses of siblings	1.1	1.5	5.9	-1.9	-1.3	-1.2	-1.3	-1.1	-1.0	-0.7	-1.3	0.9	-1.2	-2.4	-1.1	-0.9	0.4	0.2	1.3	0.4
Medication: Lansoprazole	1.1	1.2	1.9	0.3	-1.3	-1.3	-1.4	-1.3	-1.2	-1.3	-0.6	-0.7	-1.3	-0.1	-1.3	1.2	1.3	1.1	0.3	1.2
Illnesses of mother	1.1	1.4	3.2	1.3	-1.2	-1.3	-1.3	-1.1	-1.0	-1.3	-0.8	-0.2	-1.1	0.8	-1.1	1.8	1.1	1.6	0.9	1.5
Chest pain or discomfort	1.1	1.6	2.8	1.1	1.3	1.2	1.2	1.3	1.7	1.2	1.4	-1.2	1.2	1.5	1.5	-1.5	-1.2	-0.6	0.2	-1.2
Ever had hysterectomy (womb removed)	1.0	1.1	4.3	1.8	1.0	1.3	0.8	0.9	0.8	0.6	1.1	-1.2	1.0	2.1	1.1	0.2	-0.8	0.7	-0.2	-0.7
Pack years adult smoking proportion	1.0	1.5	4.0	-0.5	-1.1	-1.4	-1.0	-1.0	-2.0	-0.9	-1.8	0.4	-1.0	-1.1	-1.1	0.7	1.3	1.9	0.9	1.2
Waist circumference	1.0	3.5	6.6	-0.5	2.5	1.9	2.4	2.5	1.0	2.3	1.7	0.9	2.5	-0.3	2.6	-1.3	-2.4	-1.3	-0.2	-2.4
Falls in the last year	1.0	1.4	2.8	0.8	1.3	1.2	1.1	1.3	1.1	1.2	1.6	0.3	1.3	1.1	1.4	-1.7	-1.3	-0.8	-0.0	-1.3
Happiness	1.0	1.2	4.5	1.7	1.0	1.1	1.0	0.9	1.0	0.6	1.0	0.1	1.0	1.9	0.8	-0.7	-0.4	-0.2	-2.1	-0.5
Age at first live birth	1.0	1.9	4.2	-0.7	1.4	1.4	1.3	1.3	1.0	1.4	1.6	1.6	1.4	-0.4	1.5	-1.3	-2.0	-1.6	0.6	-1.7
Family relationship satisfaction	1.0	1.2	2.4	-1.1	1.0	1.3	1.1	0.9	1.0	1.3	0.7	1.1	1.0	-0.1	1.1	-1.1	-1.0	-1.6	-1.0	-1.5
Leg pain on walking	1.0	1.3	4.1	-0.7	-1.2	-1.1	-1.3	-1.1	-1.2	-1.1	-1.1	-1.4	-1.1	-0.9	-0.9	0.2	0.9	2.0	1.1	1.0
Illness, injury, bereavement, stress in last 2 years	1.0	1.2	3.5	1.1	1.1	1.0	1.4	1.2	0.7	1.2	0.8	-0.6	1.2	1.5	1.1	-0.6	-0.6	-0.8	-1.9	-0.6
Supplements: Vitamin C	1.0	1.2	3.0	-0.5	1.2	0.8	1.3	1.2	1.5	1.3	0.2	1.0	1.2	0.0	1.1	-1.7	-1.1	-0.9	-0.8	-1.5
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	1.0	1.2	4.6	-1.6	-1.0	-1.4	-0.8	-1.0	-1.1	-0.7	-1.0	1.6	-1.0	-2.2	-1.1	-0.8	0.7	0.2	0.1	0.2
Heart disease (siblings)	1.0	1.2	4.6	1.1	1.0	1.1	1.1	0.9	0.9	0.9	1.6	-0.2	1.0	1.7	1.0	0.6	-0.1	-0.7	-2.1	-0.1
Alzheimer’s Disease (in father)	0.9	1.0	7.3	-0.4	-0.7	-0.8	-0.6	-0.8	-0.7	-0.2	0.3	2.7	-0.8	-0.7	-0.8	0.4	1.1	-1.2	-0.7	1.1
Medication: Atenolol	0.9	1.1	2.8	-0.2	1.0	0.8	1.1	1.2	0.9	1.4	1.7	-0.4	1.1	-0.2	1.2	-1.0	-1.4	-0.9	1.1	-1.3
Diabetes (self-reported)	0.9	1.4	6.4	1.4	-0.5	-0.3	-0.8	-0.5	-2.1	-1.1	-1.2	-0.7	-0.5	1.3	-0.6	1.3	0.9	2.5	-0.2	1.1
Seen doctor (GP) for nerves, anxiety, tension or depression	0.9	1.4	3.1	-0.4	1.1	1.0	1.0	1.2	1.8	1.1	1.6	1.5	1.1	-0.5	1.2	-0.7	-1.6	-1.3	0.4	-1.5
Glaucoma (self-reported)	0.9	1.0	3.7	-0.8	-0.8	-0.4	-1.0	-0.9	-0.1	-0.6	-1.9	-1.7	-0.9	-0.7	-0.7	1.5	0.5	0.3	1.4	0.7
Seen a psychiatrist for nerves, anxiety, tension or depression	0.9	1.2	3.9	-0.6	0.9	0.8	1.1	1.0	1.4	1.1	1.4	1.3	1.0	-0.3	0.9	-0.9	-1.1	-2.0	-0.8	-1.2
Age at last live birth	0.9	1.3	2.6	-0.0	1.3	1.3	1.2	1.2	1.4	1.3	1.4	0.7	1.3	0.4	1.4	-0.9	-1.6	-1.1	0.6	-1.2
Guilty feelings	0.9	1.3	4.2	2.1	1.2	0.8	1.1	1.2	1.2	0.2	0.7	-1.4	1.3	1.8	1.2	0.0	-1.1	1.2	-0.5	-0.7
Ever smoked	0.9	1.6	3.4	1.6	1.5	1.3	1.6	1.4	1.5	0.9	0.6	0.3	1.5	1.8	1.4	-0.5	-1.0	-0.4	-1.4	-0.8
Vascular/heart problems diagnosed by doctor	0.9	2.6	9.1	0.8	-1.3	-1.0	-1.5	-1.2	-1.4	-1.8	-2.1	-3.0	-1.2	0.4	-1.5	1.7	1.3	2.7	0.4	1.6
Supplements: Calcium	0.9	1.0	4.0	1.4	0.8	1.1	0.7	0.9	1.3	0.6	0.6	-1.4	1.0	2.0	1.0	-0.2	-1.1	0.4	0.0	-0.6
Ulcerative Colitis (UC)	0.8	1.4	4.6	-1.0	-1.0	-0.8	-0.9	-1.1	-2.1	-1.2	-1.8	-1.1	-0.9	-0.9	-1.1	1.0	1.0	1.7	-0.7	0.9
Prostate Cancer	0.8	1.1	3.1	-0.3	0.8	0.5	1.0	0.7	1.6	1.0	0.7	1.6	0.7	0.1	0.6	-1.2	-0.5	-1.7	-1.6	-0.9
Crohns Disease (2012)	0.8	1.2	3.1	-0.8	1.1	1.1	1.0	1.1	1.1	1.3	0.8	1.8	1.1	-0.6	1.1	-1.1	-1.4	-1.2	0.1	-1.3
Medication: Levothyroxine sodium	0.8	1.3	7.5	-2.7	0.2	0.4	0.1	0.1	0.5	0.8	-0.3	0.8	0.0	-2.7	0.2	-1.4	-0.6	-1.3	1.2	-0.8
Alcohol usually taken with meals	0.8	1.2	6.6	-0.7	-0.8	-0.8	-1.1	-0.7	0.7	-0.5	-1.1	-2.5	-0.8	-0.9	-0.6	0.0	0.0	0.9	2.6	0.3
Forced expiratory volume in 1-second (FEV1)	0.8	2.7	6.5	2.1	1.9	1.7	1.3	1.8	2.1	1.2	0.6	-1.4	1.9	2.5	1.9	0.2	-1.9	1.3	0.7	-1.5
Forced expiratory volume in 1-second (FEV1), Best measure	0.8	2.4	5.5	1.3	1.8	1.7	1.2	1.7	2.3	1.4	0.6	-1.3	1.8	1.7	1.9	0.0	-2.0	0.8	1.4	-1.6
Overall health rating	0.8	1.8	6.8	0.5	1.6	1.3	1.7	1.5	1.2	1.2	2.6	0.0	1.5	0.9	1.4	-1.1	-1.1	-0.8	-1.3	-1.1
Number of self-reported non-cancer illnesses	0.8	1.4	4.6	-1.5	1.0	0.8	0.8	1.0	1.2	1.2	1.2	2.1	1.0	-1.0	1.3	-0.9	-1.4	0.0	1.3	-1.3
Commuting to job workplace: Public transport	0.8	0.9	3.6	-1.0	-0.9	-0.8	-0.9	-0.8	-1.6	-0.6	-1.9	-0.8	-0.8	-1.1	-0.7	-1.0	0.4	0.8	0.9	-0.1
Medication: Atorvastatin	0.8	1.0	4.3	-0.5	-0.8	-0.5	-1.1	-0.8	-2.1	-1.0	-1.6	-0.0	-0.8	-0.8	-0.7	0.8	0.5	1.4	0.7	0.8
Ever had prostate specific antigen (PSA) test	0.8	0.9	6.8	-1.4	-0.3	-0.6	-0.2	-0.4	0.6	0.0	0.5	2.6	-0.4	-1.3	-0.5	-0.2	0.6	-1.0	-1.3	0.5
Depressed Affect (Nagel 2018)	0.7	1.5	3.5	-0.3	-1.2	-1.2	-1.2	-1.4	-0.6	-1.5	-1.0	-1.3	-1.3	-0.5	-1.3	1.9	1.6	1.3	0.0	1.4
Type 2 Diabetes (T2D) (2012)	0.7	0.9	2.6	0.5	-1.0	-1.1	-1.2	-0.9	-0.8	-0.8	-0.8	0.2	-1.1	0.2	-0.8	1.6	1.0	1.0	0.5	1.0
Waist Hip Ratio (WHR)	0.7	3.2	6.5	-2.0	-2.0	-2.3	-1.9	-2.0	-1.8	-1.6	-1.5	1.0	-2.0	-2.5	-2.1	0.8	1.8	1.4	1.2	1.7
Type 2 Diabetes (T2D) (2018)	0.7	1.2	6.6	1.1	-0.3	-0.1	-0.6	-0.5	-1.9	-1.1	-1.1	-1.6	-0.3	0.8	-0.5	0.8	0.8	2.6	-0.3	1.1
Number of treatments/medications taken	0.7	1.3	3.5	-0.2	1.1	1.0	1.3	1.1	1.4	1.3	1.9	1.2	1.1	0.2	1.3	-0.9	-1.1	-1.1	0.1	-1.3
Qualifications: CSEs or equivalent	0.7	0.9	1.7	0.3	-1.1	-1.3	-1.1	-1.2	-0.2	-1.0	-0.7	-0.4	-1.2	-0.3	-1.2	1.3	1.1	0.4	0.7	1.3
Serious illness, injury or assault to yourself	0.7	0.8	4.2	-2.0	-0.5	-0.4	-0.6	-0.5	0.3	-0.1	-1.1	-0.8	-0.6	-1.7	-0.4	-0.5	0.1	0.2	1.5	-0.1
Hair/balding pattern: Pattern 2	0.7	0.8	1.7	-0.6	-1.0	-1.0	-1.0	-1.0	-1.0	-0.9	-0.3	1.0	-1.1	-0.6	-1.0	1.0	1.3	0.8	-0.0	1.1
Hayfever/allergic rhinitis (self-reported)	0.7	0.9	2.3	0.6	1.3	1.5	0.9	1.1	0.2	0.5	0.3	0.3	1.2	1.0	1.1	-0.6	-1.2	1.0	-1.0	-1.2
Medication: Ramipril	0.7	0.9	7.5	0.6	0.8	0.7	0.6	0.8	-0.1	0.4	1.3	2.7	0.8	0.6	0.8	-0.4	-0.7	-0.1	-0.3	-0.6
Fluid intelligence score	0.7	1.5	4.2	-0.2	1.4	1.7	1.1	1.4	0.4	1.4	0.6	0.6	1.4	0.4	1.6	-1.2	-2.0	-1.2	0.7	-1.6
Prospective memory result	0.7	0.9	2.4	-0.1	0.9	0.7	1.0	1.0	0.9	1.0	1.5	0.2	1.0	0.3	1.0	-1.3	-1.0	-1.0	-0.5	-1.5
Hair/balding pattern: Pattern 4	0.7	1.8	5.1	0.3	1.5	1.5	1.7	1.4	1.1	1.2	1.2	-0.5	1.5	0.4	1.4	-1.2	-1.6	-2.3	-1.1	-1.6
Number of full brothers	0.7	0.9	2.6	1.2	0.9	1.1	0.8	0.9	1.6	0.7	0.8	1.0	0.9	1.3	0.9	-0.2	-0.8	-0.4	-0.1	-0.7
Medication for pain relief, constipation, heartburn	0.7	1.3	5.1	0.9	-0.9	-0.6	-1.3	-0.9	-2.3	-1.5	-1.7	-0.4	-0.9	0.5	-0.9	0.6	0.3	1.6	1.1	0.7
Migraine (self-reported)	0.7	0.8	4.3	-2.1	0.4	0.2	0.6	0.3	0.8	0.3	-0.6	1.7	0.4	-1.8	0.2	-0.8	-0.5	-0.1	-0.8	-0.6
Handedness (chirality/laterality): Left-handed	0.7	0.8	3.3	0.3	-0.7	-0.4	-0.7	-0.7	-1.1	-1.1	-1.8	-1.1	-0.6	0.8	-0.6	0.7	0.7	1.5	-0.1	0.4
Friendships satisfaction	0.7	0.8	1.6	-1.1	-1.1	-1.2	-0.9	-1.0	-0.8	-0.6	-0.5	1.3	-1.0	-1.1	-0.9	0.5	1.1	0.4	-0.3	1.0
Breast cancer (self-reported)	0.7	0.8	3.3	-1.7	0.4	0.7	0.5	0.4	0.8	0.6	0.8	1.3	0.4	-0.9	0.5	-1.8	-0.4	-0.8	-0.9	-0.8
Mother’s age at death	0.7	0.9	7.7	1.3	0.3	1.0	0.0	0.4	0.7	0.2	-0.2	-2.8	0.4	1.3	0.6	-0.1	-0.4	1.3	0.5	-0.1
Pack years of smoking	0.7	1.0	3.2	-0.8	-0.8	-1.0	-0.8	-0.7	-1.8	-0.6	-1.7	0.2	-0.8	-1.2	-0.8	0.3	0.9	1.6	0.8	0.9
Breast Cancer	0.6	1.5	6.0	0.7	-1.0	-0.5	-1.3	-0.9	-0.3	-1.2	-1.8	-2.4	-0.9	0.3	-0.7	0.5	0.5	2.3	1.7	1.0
Systolic blood pressure, automated reading	0.6	1.8	6.6	-0.8	0.9	0.8	1.2	0.9	0.7	1.3	2.2	2.6	0.8	-0.4	0.8	-1.2	-0.4	-2.5	-1.3	-1.0
Vitamin and mineral supplements	0.6	0.8	1.8	-0.5	-0.9	-0.9	-1.1	-0.9	-1.4	-0.8	-1.0	-0.4	-0.9	-1.0	-0.7	0.4	0.6	0.7	1.1	0.9
Hearing difficulty/problems with background noise	0.6	1.0	10.8	-0.2	-0.5	-0.5	-0.9	-0.4	0.3	-0.5	0.0	-1.1	-0.4	-0.6	-0.2	0.7	-0.5	1.2	3.3	0.2
Ever highly irritable/argumentative for 2 days	0.6	0.7	4.4	0.7	-0.2	-0.2	0.0	-0.4	-0.5	-0.6	-0.5	-1.3	-0.2	0.7	-0.5	0.9	1.1	0.7	-2.1	0.7
Birth weight	0.6	1.4	9.1	1.1	0.9	1.3	0.7	0.8	1.6	0.5	0.5	-3.0	0.9	1.4	0.9	-0.8	-1.1	0.2	0.1	-1.2
Pulse wave peak to peak time	0.6	0.6	1.4	0.9	1.0	0.9	0.8	0.9	1.2	0.8	0.1	0.4	1.0	0.7	0.9	-0.5	-1.0	-0.7	0.3	-0.7
Neck or shoulder pain in last month	0.6	0.8	5.0	2.2	0.0	-0.1	-0.1	0.1	0.8	-0.5	0.5	-1.5	0.0	1.9	0.0	0.2	-0.2	0.8	0.9	-0.0
Had major operations	0.6	0.7	3.9	-0.6	-0.7	-0.9	-0.7	-0.6	-0.9	-0.7	-0.5	0.3	-0.6	-0.8	-0.7	0.4	0.9	2.0	-0.5	1.0
Ever had bowel cancer screening	0.6	0.7	2.8	-1.6	0.3	0.7	0.5	0.4	1.7	1.1	0.7	-0.7	0.4	-0.5	0.6	-1.0	-0.5	-1.0	0.3	-0.8
Osteoarthritis (self-reported)	0.6	0.8	3.8	-1.9	-0.2	-0.2	-0.3	-0.2	0.5	0.3	0.2	1.8	-0.1	-1.9	-0.0	0.1	-0.4	-1.2	0.7	-0.5
Medication: Aspirin	0.6	0.8	2.5	1.1	0.8	1.0	0.8	0.8	0.7	0.5	0.7	-1.6	0.8	1.3	0.8	0.7	-0.3	0.0	-1.1	0.0
Supplements: Fish oil (including cod liver oil)	0.6	0.8	3.9	-0.2	-1.1	-0.7	-1.1	-1.0	-0.3	-0.8	-1.0	-2.0	-1.1	0.2	-1.0	0.5	1.1	0.5	0.2	0.7
Diastolic blood pressure, automated reading	0.6	2.0	6.8	-1.8	1.0	0.7	1.2	1.0	-0.1	1.5	1.2	2.6	0.9	-1.6	0.9	-2.2	-0.9	-1.7	-0.8	-1.5
Ever depressed for a whole week	0.6	0.8	2.2	1.1	1.0	1.2	0.7	0.8	0.8	0.5	1.1	-0.7	0.9	1.5	0.9	-0.4	-0.7	0.4	-0.0	-0.9
Lung FVC	0.5	2.8	13.0	1.5	-0.8	-0.6	-1.2	-0.9	0.5	-1.3	-2.0	-3.6	-0.8	1.8	-0.6	1.6	0.9	3.4	1.5	1.2
Ever used hormone-replacement therapy (HRT)	0.5	0.7	1.4	-0.1	0.7	1.1	0.8	0.9	0.9	0.8	0.6	0.1	0.8	0.5	1.0	-1.1	-1.1	-0.6	-0.5	-1.2
Current tobacco smoking	0.5	0.8	2.3	0.6	-0.8	-1.1	-0.7	-0.9	-1.5	-1.0	-0.3	-0.1	-0.9	-0.0	-1.0	0.5	1.4	1.3	-0.2	1.1
Qualifications: None of the above	0.5	1.0	2.9	-0.5	-1.0	-1.1	-0.9	-1.0	-1.1	-1.1	-0.2	0.4	-1.0	-0.8	-1.0	1.0	1.4	1.7	0.0	1.3
Financial difficulties in last 2 years	0.5	0.6	2.7	-1.6	0.4	-0.0	0.7	0.3	0.9	1.1	0.8	1.0	0.3	-1.3	0.3	-0.8	-0.0	-1.0	-0.2	-0.6
Mouth/teeth dental problems	0.5	0.7	3.1	0.3	0.4	0.6	0.4	0.6	0.8	0.8	1.0	1.8	0.5	0.9	0.5	-0.3	-0.6	-1.7	0.1	-0.9
Allergy	0.5	1.1	2.3	-1.4	-1.2	-1.3	-1.0	-1.1	-1.1	-0.7	-1.4	-0.3	-1.1	-1.5	-1.0	-0.1	0.6	0.2	1.5	0.2
Loud music exposure frequency	0.5	0.6	1.4	0.0	1.0	1.2	0.8	0.9	0.5	0.9	0.8	0.5	0.9	0.8	1.0	-0.1	-0.6	0.4	-0.7	-0.7
Mean time to correctly identify matches	0.5	0.9	3.8	-0.9	0.9	1.4	0.8	0.8	0.5	1.0	0.7	-1.9	0.9	-0.1	1.1	-0.5	-0.7	-0.7	-0.3	-1.0
Heart disease (mother)	0.5	0.6	2.6	-1.4	0.3	0.5	0.7	0.2	0.3	0.9	0.4	-0.0	0.2	-0.7	0.3	-1.2	0.2	-1.4	-1.6	-0.6
Number of full sisters	0.5	0.6	2.3	1.3	0.8	0.9	0.4	0.7	0.4	0.2	0.3	-0.8	0.7	1.5	0.7	0.0	-0.8	0.8	0.0	-0.6
Medication: Aspirin	0.5	0.7	2.1	0.9	0.8	1.0	0.9	0.8	0.8	0.6	0.6	-1.3	0.8	1.1	0.8	0.5	-0.3	-0.0	-1.4	-0.1
Long-standing illness, disability or infirmity	0.5	0.8	1.8	0.2	1.1	1.3	0.9	1.1	1.2	0.7	1.2	-0.5	1.1	0.7	1.2	-0.2	-1.1	0.2	-0.1	-0.7
Eye problems/disorders: Cataract	0.5	0.6	3.1	1.8	0.2	0.3	0.2	0.2	0.4	-0.1	0.6	-1.0	0.2	1.5	0.0	-0.6	0.2	0.5	-1.3	0.4
Mouth/teeth dental problems: Mouth ulcers	0.5	0.8	2.6	-1.4	0.6	0.3	0.6	0.6	1.0	1.1	1.0	0.5	0.5	-1.6	0.6	-0.8	-0.7	-0.8	1.0	-0.7
Pain type(s) experienced in last month: Hip pain	0.5	0.6	2.3	0.2	-0.7	-0.8	-0.8	-0.7	-0.1	-0.8	0.4	-1.4	-0.7	0.1	-0.6	1.5	0.9	0.8	0.5	0.9
Risk taking	0.5	0.7	2.2	-0.4	-1.1	-1.2	-1.0	-1.0	0.3	-0.8	-1.5	0.3	-1.0	-0.6	-1.0	-0.1	0.9	0.4	1.1	0.5
Schizophrenia (2018)	0.4	0.8	1.9	0.1	1.0	1.2	1.2	0.9	0.2	1.0	0.9	-0.3	1.1	0.8	1.0	0.1	-0.7	-1.4	-1.4	-0.6
Schizophrenia vs Biploar Disorder	0.4	0.6	1.1	0.7	0.9	0.9	1.0	1.0	-0.3	0.3	-0.2	0.2	1.0	0.6	0.8	-0.9	-0.9	0.1	-1.0	-0.8
Primary Biliary Cirrhosis	0.4	0.6	2.5	1.4	-0.0	0.4	-0.5	-0.0	-0.4	-0.4	-0.7	-0.5	0.0	1.4	0.0	1.2	0.1	1.6	0.3	0.4
Ulcerative Colitis	0.4	0.5	2.9	-0.1	-0.6	-0.4	-0.6	-0.6	-1.0	-0.8	-0.8	-0.6	-0.5	-0.4	-0.6	1.0	0.3	1.7	0.5	0.6
Relative age of first facial hair	0.4	0.9	6.6	-0.7	-0.4	-0.7	0.2	-0.5	-0.1	-0.2	0.2	1.7	-0.4	-0.6	-0.6	-0.8	1.0	-1.0	-2.6	0.4
Angina	0.4	0.6	5.1	0.5	0.5	0.9	0.6	0.5	0.5	0.6	-0.2	-2.3	0.6	0.9	0.7	-0.3	-0.4	-0.3	-0.5	-0.5
Supplements: Zinc	0.4	0.4	3.6	-0.0	-0.4	-0.5	-0.4	-0.2	0.5	-0.0	-0.5	-1.9	-0.3	0.0	-0.1	0.0	-0.1	-0.4	1.3	0.1
Tinnitus: Yes, but not now, but have in the past	0.4	0.4	4.8	-0.7	0.2	0.2	0.7	0.2	-0.4	0.4	-0.1	0.5	0.3	-0.3	-0.1	-0.5	0.4	-0.2	-2.2	-0.2
Number of incorrect matches in round	0.4	0.6	1.5	-1.2	-0.7	-1.0	-0.3	-0.7	-0.1	-0.5	-0.7	1.0	-0.8	-1.0	-0.6	-0.1	1.1	0.0	-0.8	0.7
Lung cancer (father)	0.4	0.5	2.6	0.6	-0.6	-0.5	-0.8	-0.5	-0.7	-0.8	-0.8	0.9	-0.5	0.3	-0.4	0.6	0.2	0.9	1.6	0.1
Peak expiratory flow (PEF)	0.4	1.0	2.2	0.0	1.3	1.2	1.1	1.2	1.5	1.0	-0.2	0.9	1.3	0.3	1.2	-0.9	-1.2	0.4	-0.4	-1.2
Qualifications: O levels/GCSEs or equivalent	0.4	0.7	3.1	1.1	0.4	0.3	-0.2	0.4	0.7	0.3	-0.2	-1.8	0.4	0.9	0.6	-0.2	-1.0	0.7	1.7	-0.4
Medication for cholesterol, blood pressure or diabetes	0.4	0.7	6.8	0.5	-0.3	0.4	-0.4	-0.3	-0.3	-0.3	-0.5	-2.6	-0.3	0.9	-0.4	1.0	0.4	1.2	0.2	0.4
Wheeze or whistling in the chest in last year	0.4	0.8	4.6	1.1	-0.4	-0.4	-0.5	-0.5	-0.7	-1.1	-0.3	0.1	-0.4	0.9	-0.5	1.3	0.8	2.1	-0.3	1.0
Eye problems/disorders: None of the above	0.4	0.4	1.3	-0.5	0.5	0.4	0.8	0.6	0.3	0.8	0.9	1.1	0.5	-0.2	0.5	-0.8	-0.3	-1.2	-0.6	-0.5
Angina (self-reported)	0.4	0.5	5.7	0.6	0.2	0.6	0.3	0.2	0.2	0.2	-0.5	-2.4	0.2	1.0	0.4	-0.2	-0.1	-0.0	-0.6	-0.2
Knee pain experienced in last month	0.4	0.7	4.0	-2.0	-0.2	-0.3	-0.2	-0.2	0.2	0.3	0.0	1.4	-0.3	-1.7	-0.2	-0.7	-0.1	-1.2	0.4	-0.4
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.4	0.5	1.7	-0.1	0.7	0.7	0.8	0.7	1.3	0.7	0.2	0.5	0.7	0.1	0.7	-0.7	-0.8	-1.2	-0.2	-0.7
Back pain experienced in last month	0.4	0.6	3.0	0.7	0.2	0.1	0.0	0.1	1.0	0.1	0.9	-1.7	0.2	0.7	0.4	1.2	-0.4	0.4	1.6	-0.0
Financial situation satisfaction	0.4	0.5	1.5	-0.7	-0.7	-0.6	-0.4	-0.7	-0.3	-0.4	-1.1	-0.1	-0.7	-0.6	-0.9	-0.1	1.2	0.4	-1.0	0.7
Medication: Paracetamol	0.4	0.7	2.4	-1.6	-0.3	-0.3	0.1	-0.1	1.1	1.0	0.6	-0.0	-0.3	-1.2	-0.0	-1.2	0.3	-1.4	0.9	-0.2
Commuting to job workplace: Cycle	0.4	0.5	3.9	-1.4	-0.1	-0.2	-0.1	-0.2	0.9	0.4	0.2	0.0	-0.3	-0.9	-0.1	0.6	-0.0	-2.0	0.4	-0.3
Intelligence (Savage-Jansen 2018)	0.3	0.9	3.9	1.8	0.7	0.9	0.2	0.7	-0.1	-0.2	-0.6	-1.1	0.8	2.0	0.9	0.5	-1.3	0.9	0.6	-0.2
Neuroticism (Nagel 2018)	0.3	0.7	3.2	0.8	-0.5	-0.7	-0.7	-0.5	0.0	-1.1	-0.4	-1.0	-0.5	0.5	-0.6	1.8	0.6	1.2	0.1	0.9
Reaction Time	0.3	0.6	3.5	-0.3	0.9	1.2	0.7	0.7	0.0	0.6	0.5	-1.9	0.8	0.1	0.9	-0.5	-0.6	0.4	-0.4	-0.8
Body Mass Index (BMI) (2010)	0.3	0.4	1.9	0.5	0.4	0.5	0.2	0.4	0.1	0.4	1.4	1.0	0.3	0.5	0.5	0.5	-0.3	-0.9	0.3	-0.5
Schizophrenia (2014)	0.3	0.6	1.9	1.1	0.8	1.1	0.7	0.7	0.2	0.7	0.5	-1.3	0.8	1.4	0.9	0.5	-0.5	-0.7	-0.4	-0.1
Systolic Blood Pressure	0.3	1.3	10.4	-0.7	0.5	0.2	0.7	0.4	0.7	0.7	1.4	3.2	0.4	-0.7	0.2	-0.1	-0.2	-2.3	-0.6	-0.5
Neuroticism	0.3	0.8	3.1	0.6	-0.5	-0.5	-0.6	-0.6	-0.1	-1.2	-0.4	-1.7	-0.5	0.1	-0.6	1.8	0.6	1.4	0.1	0.9
Sensitivity / hurt feelings	0.3	0.5	6.7	0.1	-0.3	-0.3	-0.5	-0.3	-0.0	-0.4	-0.5	-2.6	-0.3	-0.1	-0.2	0.4	0.2	1.0	0.5	0.4
Average weekly fortified wine intake	0.3	0.4	2.4	1.6	-0.1	0.0	-0.3	-0.1	0.0	-0.5	1.0	-0.4	-0.1	1.2	-0.1	0.5	0.0	0.3	0.5	0.2
Bilateral oophorectomy (both ovaries removed)	0.3	0.3	1.1	1.0	0.4	0.6	0.4	0.5	0.2	0.5	0.0	-0.5	0.5	0.8	0.6	-0.6	-0.6	0.2	0.7	-0.5
Past tobacco smoking	0.3	0.5	2.3	-1.4	-0.6	-0.2	-0.9	-0.5	-0.3	-0.0	0.1	-0.8	-0.7	-1.3	-0.5	-0.1	0.1	-0.1	1.5	0.0
Ever unenthusiastic/disinterested for a whole week	0.3	0.4	1.0	0.6	-0.5	-0.2	-0.6	-0.7	-0.5	-1.0	-0.7	-0.1	-0.6	0.5	-0.6	0.4	0.6	1.0	-0.1	0.4
Arm fat percentage (right)	0.3	1.3	2.9	-0.7	1.3	0.8	1.6	1.3	0.1	1.2	1.1	0.9	1.3	-0.9	1.1	-1.6	-0.8	-1.0	-1.7	-0.8
Time employed in main current job	0.3	0.3	0.7	-0.5	0.4	0.3	0.4	0.5	0.6	0.5	0.1	-0.8	0.5	-0.6	0.4	-0.8	-0.9	-0.2	0.5	-0.8
Tense / ‘highly strung’	0.3	0.4	1.9	1.4	-0.1	-0.1	-0.3	-0.2	-0.1	-0.8	-0.3	-0.8	-0.1	1.2	-0.1	0.9	-0.0	1.1	0.2	0.4
Medication: Paracetamol	0.3	0.5	2.3	-1.1	-0.2	-0.3	0.3	-0.0	1.1	1.0	0.8	-0.1	-0.2	-0.8	0.0	-0.9	0.4	-1.5	0.2	0.1
Gout (self-reported)	0.3	0.4	1.6	0.2	0.6	0.5	0.8	0.6	0.5	0.6	0.8	1.3	0.6	0.5	0.5	-0.6	-0.3	-0.8	-0.9	-0.3
Hypothyroidism/myxoedema (self-reported)	0.3	0.6	2.2	-1.5	0.7	0.8	0.6	0.5	0.6	0.6	-0.4	0.1	0.5	-1.3	0.5	-1.1	-0.8	-1.1	-0.3	-0.8
Medication: Ventolin 100micrograms inhaler	0.3	0.4	1.8	-0.6	-0.2	-0.3	-0.1	-0.2	0.2	0.4	1.2	1.3	-0.2	-0.7	0.1	-0.7	-0.1	-1.0	1.3	-0.2
Leg fat percentage (right)	0.3	1.1	3.4	-1.8	0.6	0.4	1.1	0.7	-0.6	0.8	1.0	1.3	0.6	-1.8	0.5	-1.3	-0.1	-1.1	-1.5	-0.5
Exposure to tobacco smoke outside home	0.3	0.4	2.5	-1.0	-0.3	-0.2	-0.1	-0.3	-0.5	-0.1	-1.2	-1.6	-0.3	-0.8	-0.3	-0.5	0.5	0.3	-0.3	0.3
Comparative body size at age 10	0.3	0.9	2.3	0.6	1.2	1.2	1.3	1.1	-0.5	0.8	0.6	-0.7	1.2	0.6	1.0	-0.9	-1.0	-0.3	-1.5	-0.8
Medication: Seretide 50 evohaler	0.3	0.4	1.4	0.9	0.3	0.2	0.2	0.1	0.7	-0.2	0.1	-1.1	0.2	1.2	0.2	0.9	0.0	-0.6	-0.8	-0.1
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.3	0.4	1.4	0.7	0.2	0.2	0.6	0.3	0.9	0.7	0.8	-0.5	0.2	0.7	0.2	0.2	0.3	-1.2	-0.9	0.3
Commuting to job workplace: Car/motor vehicle	0.3	0.4	2.0	-1.4	-0.5	-0.5	-0.3	-0.4	0.1	-0.1	-0.4	-0.8	-0.4	-1.1	-0.4	0.7	0.5	-0.6	-0.4	0.5
Illnesses of father: Heart disease	0.3	0.4	2.5	0.3	0.0	0.4	0.0	-0.1	-0.5	-0.3	0.4	-0.1	-0.0	0.7	-0.1	1.6	0.7	0.3	-1.5	0.4
Arm fat percentage (left)	0.3	1.0	1.8	-1.1	1.0	0.5	1.3	1.0	-0.1	1.0	1.0	1.0	1.0	-1.4	0.9	-1.3	-0.6	-1.0	-1.3	-0.7
Commuting to job workplace: Walk	0.3	0.3	2.3	-0.2	-0.1	-0.4	-0.1	-0.1	-0.2	-0.1	-0.5	1.0	-0.2	-0.7	-0.1	-0.8	-0.2	0.7	1.5	-0.3
Osteoporosis (self-reported)	0.3	0.3	2.0	0.0	-0.5	-0.3	-0.7	-0.5	0.8	-0.4	0.6	-0.0	-0.5	0.2	-0.5	1.4	0.4	0.0	0.8	0.5
Smoking status: Current	0.3	0.5	1.3	0.7	-0.6	-0.9	-0.5	-0.7	-1.1	-0.7	0.1	-0.5	-0.7	0.1	-0.8	0.3	1.1	1.0	-0.1	0.8
Wears glasses or contact lenses	0.3	0.3	1.5	-0.0	-0.5	-0.2	-0.7	-0.3	-0.1	-0.4	-0.5	0.3	-0.3	-0.1	-0.1	-0.9	-0.2	1.0	1.2	0.1
Medication: Blood pressure	0.3	0.6	2.5	0.2	0.7	0.8	0.7	0.7	0.5	1.0	1.6	0.4	0.7	0.5	0.9	-0.8	-0.6	-0.8	0.2	-0.9
Medication: Lisinopril	0.3	0.3	2.2	0.9	0.4	0.1	0.3	0.3	0.1	0.2	1.5	1.0	0.3	1.0	0.4	0.2	-0.2	-0.2	-0.0	-0.0
Leg fat percentage (left)	0.3	1.2	4.0	-1.8	0.7	0.4	1.1	0.7	-0.6	0.7	1.2	1.3	0.6	-2.0	0.5	-1.3	-0.2	-1.0	-1.5	-0.6
Average weekly beer plus cider intake	0.3	0.4	1.1	0.6	0.8	0.7	0.9	0.7	0.7	0.5	0.4	0.2	0.8	0.8	0.6	-0.1	-0.5	-0.4	-1.1	-0.6
Irritability	0.3	0.6	3.4	-0.4	-0.5	-0.7	-0.7	-0.6	-0.5	-0.8	-0.8	-0.4	-0.6	-0.5	-0.6	1.8	0.5	1.1	0.4	0.9
Age started oral contraceptive pill	0.3	0.4	0.8	-0.5	-0.7	-0.6	-0.6	-0.7	-0.4	-0.8	-0.8	-0.8	-0.6	-0.3	-0.8	0.4	0.7	0.6	-0.9	0.6
Cholesterol lowering medication	0.3	0.4	1.5	1.0	0.6	0.8	0.3	0.5	-0.1	0.2	0.4	-0.8	0.6	1.2	0.7	0.4	-0.6	0.9	0.3	-0.6
Basal cell carcinoma (self-reported)	0.3	0.3	1.4	0.8	0.2	0.4	0.1	0.1	0.8	-0.1	0.1	0.1	0.1	1.0	0.0	1.2	-0.0	-0.6	-1.1	0.1
Bipolar Disorder (2018)	0.2	0.4	0.8	0.6	-0.6	-0.6	-0.6	-0.5	-0.6	-0.4	-0.0	-0.9	-0.5	0.3	-0.4	0.9	0.7	0.2	0.8	0.8
Depression (Nagel 2018)	0.2	0.3	2.1	-0.1	0.3	0.1	0.3	0.2	1.1	0.3	0.4	-1.5	0.2	-0.1	0.1	0.5	-0.1	-0.7	0.3	-0.0
Worry (Nagel 2018)	0.2	0.4	1.5	1.2	0.5	0.3	0.3	0.4	0.3	-0.1	1.1	0.2	0.5	1.2	0.3	0.7	-0.3	0.1	-0.6	-0.1
Crohns Disease (2017)	0.2	0.5	2.2	-1.2	0.8	0.7	0.8	0.6	0.1	0.7	-0.2	1.5	0.7	-0.9	0.6	-0.2	-0.7	-0.0	-0.5	-0.8
Irritable Bowel Disease (IBD)	0.2	0.5	1.6	-1.2	-0.0	0.1	0.1	-0.2	-1.2	-0.3	-1.2	0.2	0.0	-1.0	-0.2	0.4	0.1	1.0	-1.3	0.1
Mean Putamen Volume	0.2	0.2	0.8	-0.7	-0.2	-0.1	-0.1	-0.2	0.4	0.1	0.4	0.7	-0.3	-0.7	-0.2	-0.3	0.2	-0.9	-0.2	0.1
HDL Cholesterol	0.2	0.4	2.8	0.0	0.5	0.7	0.6	0.5	0.0	0.5	-0.1	-1.7	0.7	0.5	0.7	-0.1	-0.5	0.1	-0.4	-0.1
LDL Cholesterol	0.2	0.3	1.3	-0.6	-0.3	-0.5	0.4	-0.1	0.8	0.5	0.6	0.3	0.1	-1.0	-0.2	-0.4	0.1	-1.1	-0.2	-0.4
Rheumatoid Arthritis	0.2	0.2	1.6	0.1	-0.3	-0.0	-0.4	-0.3	-0.1	-0.4	-0.9	0.1	-0.3	0.1	-0.4	1.3	0.3	-0.0	-0.2	0.6
Blood Eosinophil Count	0.2	1.4	2.9	-0.0	1.2	0.8	1.4	1.3	0.8	1.5	1.3	0.5	1.3	-0.0	1.4	-1.7	-1.3	-1.7	-0.2	-1.3
Smoking Status	0.2	0.4	2.9	0.5	0.1	-0.5	0.4	0.0	-0.4	-0.1	0.8	1.7	0.1	0.0	-0.1	0.4	0.6	0.6	-0.9	0.5
Cardiovascular Disease	0.2	0.6	3.6	-0.8	0.6	0.1	0.6	0.5	0.3	0.5	1.3	1.9	0.6	-1.0	0.6	-0.6	-0.7	-0.5	0.4	-0.6
Respiratory disease	0.2	0.4	1.4	-0.7	-0.5	-0.4	-0.4	-0.6	-0.5	-0.3	1.2	0.2	-0.6	-0.9	-0.5	0.2	0.6	-1.0	0.1	0.5
Frequency of depressed mood in last 2 weeks	0.2	0.2	1.1	-0.5	0.2	-0.3	0.3	0.3	1.0	0.2	0.2	0.3	0.2	-0.5	0.2	0.3	-0.6	-0.9	0.7	-0.6
Other serious medical condition/disability diagnosed by doctor	0.2	0.3	0.6	-0.3	0.6	0.7	0.5	0.5	0.6	0.4	0.2	-0.8	0.5	0.4	0.7	-0.8	-0.4	0.8	-0.2	-0.7
Eye problems/disorders: Diabetes related eye disease	0.2	0.2	0.6	0.2	-0.3	-0.2	-0.5	-0.4	-0.7	-0.6	-0.2	0.7	-0.3	0.2	-0.3	0.7	0.1	0.3	0.5	0.4
Medication: Co-codamol	0.2	0.2	0.4	-0.1	-0.4	-0.5	-0.4	-0.5	-0.1	-0.4	0.6	0.2	-0.4	-0.4	-0.5	0.7	0.6	-0.2	-0.0	0.5
Trunk fat percentage	0.2	0.8	1.9	-1.1	0.9	0.3	1.1	0.9	-0.4	0.8	1.1	1.4	0.9	-1.3	0.8	-0.7	-0.6	-0.6	-0.9	-0.6
Townsend deprivation index at recruitment	0.2	0.3	0.8	0.7	0.6	0.6	0.6	0.5	0.0	0.4	0.1	0.9	0.5	0.7	0.4	0.3	-0.0	-0.1	-0.9	-0.1
Fed-up feelings	0.2	0.3	1.4	-0.7	-0.1	-0.3	-0.0	-0.3	0.1	-0.5	-0.5	0.0	-0.3	-0.7	-0.4	1.2	0.6	0.6	-0.6	0.5
Frequency of unenthusiasm / disinterest in last 2 weeks	0.2	0.2	0.4	-0.4	-0.4	-0.5	-0.3	-0.5	0.6	-0.3	0.2	-0.7	-0.6	-0.4	-0.5	0.6	0.6	-0.5	0.6	0.3
Multivitamins +/- minerals	0.2	0.2	0.5	0.0	0.3	0.4	0.5	0.4	0.5	0.4	0.7	-0.5	0.4	0.1	0.2	-0.5	-0.6	-0.6	0.2	-0.7
Supplements: Glucosamine	0.2	0.2	0.7	-0.2	-0.8	-0.7	-0.7	-0.7	-0.1	-0.5	-0.0	0.0	-0.7	-0.1	-0.7	0.4	0.6	0.1	0.4	0.4
Diverticular disease/diverticulitis (self-reported)	0.2	0.2	1.1	-0.7	0.0	-0.1	0.1	0.2	-0.5	0.2	0.2	0.1	0.2	-0.5	0.3	-1.0	-0.2	0.9	0.4	-0.1
Frequency of tenseness / restlessness in last 2 weeks	0.2	0.4	1.1	-1.0	-0.5	-0.7	-0.4	-0.7	0.3	-0.6	-0.0	0.7	-0.7	-1.0	-0.8	-0.1	0.6	-0.4	-0.4	0.2
Medication: Simvastatin	0.2	0.3	1.9	-0.1	-0.3	-0.5	-0.3	-0.3	-1.0	-0.5	0.1	0.5	-0.2	-0.2	-0.2	0.5	0.5	1.4	-0.1	0.4
Neuroticism score	0.2	0.4	2.6	0.7	0.1	0.0	-0.1	-0.1	0.3	-0.6	0.2	-1.6	0.1	0.5	-0.0	1.2	0.1	1.2	-0.2	0.5
Worrier / anxious feelings	0.2	0.4	1.4	-0.9	0.3	-0.0	0.4	0.2	0.7	0.4	0.9	1.2	0.3	-0.8	0.2	-0.3	-0.4	-1.1	-0.7	-0.5
Pulse rate	0.2	0.3	1.3	-0.6	0.3	0.5	0.6	0.2	-0.0	0.6	0.4	0.3	0.2	-0.5	0.0	-0.7	0.1	-0.9	-1.2	-0.1
Exposure to tobacco smoke at home	0.2	0.3	0.9	0.6	0.6	0.6	0.5	0.5	0.4	0.5	0.3	-0.9	0.5	0.9	0.5	0.2	-0.3	-0.2	-0.1	-0.3
Breastfed as a baby	0.2	0.3	1.4	-0.7	-0.0	0.3	0.1	0.2	-0.4	0.5	1.2	0.7	0.1	-0.3	0.3	-1.0	-0.2	-0.1	0.2	-0.6
Pulse wave reflection index	0.2	0.3	1.0	-1.0	-0.5	-0.5	-0.4	-0.5	-0.5	-0.5	0.1	-0.2	-0.5	-1.0	-0.5	-0.1	0.4	-0.2	-0.7	0.2
Headache pain in last month	0.2	0.3	1.1	-1.0	-0.3	-0.1	-0.2	-0.2	1.1	0.3	0.3	-0.9	-0.3	-1.0	-0.1	-1.0	0.1	-0.1	0.5	0.1
Body fat percentage	0.2	0.9	2.7	-1.4	0.8	0.3	1.1	0.8	-0.5	0.7	1.0	1.4	0.7	-1.6	0.7	-0.9	-0.4	-0.7	-1.3	-0.5
Mouth/teeth dental problems: Loose teeth	0.2	0.2	1.8	0.5	0.2	0.1	0.1	0.1	-0.6	-0.2	-0.8	-1.4	0.1	0.0	0.2	0.7	-0.1	0.4	0.3	0.2
Medication: Allopurinol	0.2	0.3	0.9	0.9	0.5	0.4	0.7	0.4	0.2	-0.1	-0.2	-0.2	0.5	1.0	0.4	-0.5	-0.3	0.5	-0.6	-0.1
Suffer from ‘nerves’	0.2	0.3	1.3	0.9	0.4	0.4	0.3	0.2	0.5	0.1	1.0	0.3	0.2	1.1	0.1	0.7	-0.0	-0.5	-0.8	0.1
Smoking status: Previous	0.2	0.3	1.4	0.8	0.0	-0.3	0.3	-0.0	-0.3	-0.6	-0.8	0.6	0.1	0.8	-0.1	0.6	0.3	0.3	-1.2	0.4
Ever had stillbirth, spontaneous miscarriage or termination	0.2	0.2	1.6	-0.4	0.0	0.2	-0.1	0.1	0.8	0.4	-0.2	1.3	-0.0	-0.3	0.2	-0.6	-0.3	-0.6	0.5	-0.3
Medication for cholesterol	0.2	0.3	0.8	-0.3	-0.5	-0.5	-0.5	-0.6	0.1	-0.6	-0.5	-0.6	-0.6	-0.6	-0.7	0.4	0.5	0.1	-0.1	0.9
Miserableness	0.2	0.3	1.6	0.3	0.4	0.5	0.3	0.3	0.8	0.1	1.3	-0.5	0.3	0.3	0.4	0.4	-0.6	-0.4	0.6	-0.4
Tinnitus: Yes, now most or all of the time	0.2	0.2	1.2	-0.8	0.1	0.2	-0.0	0.1	-0.5	0.0	0.4	-1.1	0.1	-0.6	0.1	-0.4	-0.3	0.3	0.6	-0.5
Medication: Bendroflumethiazide	0.2	0.3	2.1	-0.0	-0.0	-0.1	0.2	-0.0	0.6	0.5	1.2	0.8	-0.1	-0.2	-0.1	-0.4	0.6	-1.5	-0.6	0.3
Number of operations (self-reported)	0.2	0.3	1.5	-0.8	0.2	0.1	0.4	0.2	0.5	0.2	0.0	1.2	0.2	-0.7	0.1	-1.2	-0.1	0.0	-0.7	-0.4
Unable to work because of sickness or disability	0.2	0.2	0.9	-0.0	-0.2	-0.7	0.1	-0.2	1.0	0.2	0.9	-0.4	-0.3	-0.3	-0.2	0.3	0.7	-0.6	-0.1	0.5
Bipolar Disorder or Schizophrenia	0.1	0.3	0.9	0.5	0.4	0.5	0.5	0.4	-0.2	0.5	0.7	-0.7	0.5	0.8	0.5	0.7	-0.1	-1.0	-0.5	0.0
Bipolar Disorder (2011)	0.1	0.1	0.5	-0.3	-0.3	-0.3	-0.3	-0.3	-0.2	-0.0	-0.1	-0.7	-0.4	-0.3	-0.4	0.7	0.5	-0.2	0.1	0.4
HbA1C	0.1	0.1	0.4	-0.5	-0.3	-0.6	-0.2	-0.2	0.0	-0.0	0.1	0.1	-0.4	-0.6	-0.2	-0.0	0.2	-0.0	0.1	-0.0
Neuroticism (2016)	0.1	0.1	0.4	0.4	-0.0	-0.1	-0.0	-0.4	-0.4	-0.2	-0.5	-0.2	-0.3	0.2	-0.3	0.3	0.6	0.4	-0.2	0.4
Blood Platelet Count	0.1	1.0	6.1	-1.0	0.7	0.4	0.9	0.5	0.5	0.9	1.2	2.5	0.6	-0.8	0.4	-0.4	-0.1	-1.2	-1.5	-0.1
Blood White Count	0.1	1.0	4.6	-0.2	-0.8	-1.1	-0.6	-0.8	-2.1	-1.0	-0.2	-0.1	-0.8	-0.8	-0.9	1.3	1.4	1.3	-0.2	1.2
Medication for hormone replacement therapy	0.1	0.1	0.6	-0.8	-0.0	-0.2	0.1	0.0	-0.0	0.0	-0.5	0.7	0.0	-0.5	0.0	-0.2	-0.1	-0.1	-0.2	-0.4
Taking other prescription medications	0.1	0.2	1.6	-1.3	0.1	0.3	0.2	0.0	0.2	0.0	0.5	0.7	0.1	-0.9	0.1	0.1	-0.1	-0.1	-0.2	-0.5
Nervous feelings	0.1	0.1	0.7	0.5	0.1	0.0	0.2	0.1	-0.1	-0.2	0.3	-0.3	0.1	0.6	0.2	0.8	0.1	0.5	-0.2	0.2
Pain all over the body in last month	0.1	0.1	0.9	0.3	0.3	0.2	0.3	0.3	0.1	0.1	0.3	0.4	0.3	0.3	0.2	-0.2	-0.1	0.2	-1.0	0.0
Frequency of tiredness / lethargy in last 2 weeks	0.1	0.1	0.3	-0.2	0.5	0.6	0.5	0.4	0.3	0.3	0.1	-0.3	0.4	-0.1	0.4	-0.4	-0.3	0.1	-0.3	-0.3
Asthma	0.1	0.2	1.0	0.1	-0.2	-0.0	-0.4	-0.4	-0.2	-0.4	1.0	0.5	-0.4	-0.0	-0.3	-0.0	0.5	-0.2	0.3	0.7
Depression (self-reported)	0.1	0.2	0.8	0.4	0.3	-0.1	0.3	0.3	0.5	0.1	0.3	0.9	0.3	0.2	0.3	-0.1	-0.5	-0.3	0.7	-0.1
Pulse wave Arterial Stiffness index	0.1	0.1	0.4	-0.6	-0.2	-0.2	-0.2	-0.2	-0.7	-0.1	0.4	-0.4	-0.2	-0.3	-0.2	0.2	0.2	0.4	-0.3	0.0
Worry too long after embarrassment	0.1	0.2	1.4	0.6	-0.1	0.1	-0.3	-0.2	-0.1	-0.5	-0.6	-1.2	-0.1	0.3	-0.2	0.9	0.1	0.4	-0.3	0.5
Number of children fathered	0.1	0.2	0.7	-0.7	-0.4	-0.1	-0.4	-0.4	-0.1	-0.7	-0.4	-0.1	-0.3	-0.8	-0.4	-0.1	0.0	0.1	0.2	0.1
Pulse rate, automated reading	0.1	0.4	1.6	-0.9	-0.3	0.3	-0.3	-0.6	-1.1	-0.4	-0.6	-1.3	-0.5	-0.9	-0.5	0.0	0.3	-0.1	-0.4	0.5
Mood swings	0.1	0.1	0.5	0.4	0.4	0.1	0.4	0.2	0.6	0.1	0.7	-0.1	0.3	0.4	0.3	0.2	-0.0	0.5	-0.6	-0.1
Mineral and other dietary supplements	0.1	0.2	1.0	0.5	0.5	0.2	0.5	0.4	-0.4	0.1	0.1	1.0	0.4	0.0	0.4	0.0	-0.2	-0.2	-0.9	0.1
Asthma (self-reported)	0.1	0.2	1.7	-0.1	0.1	0.3	-0.1	-0.1	-0.0	-0.1	1.3	0.9	-0.1	-0.2	0.1	-0.2	0.1	-0.3	0.2	0.3
Medication: Gliclazide	0.1	0.2	0.5	-0.2	0.4	0.7	0.4	0.4	0.3	0.5	-0.6	-0.6	0.4	0.3	0.4	0.2	-0.4	-0.2	-0.1	-0.3
Pain experienced in last month	0.1	0.2	1.2	-0.2	0.1	0.2	0.1	0.1	-1.1	0.1	-1.1	0.4	0.1	-0.2	-0.0	0.1	-0.1	-0.6	-0.9	-0.1
Hair Pigment	0.0	0.8	2.9	1.4	-0.4	-0.1	-0.4	-0.4	-1.2	-0.9	-0.9	-1.0	-0.3	1.0	-0.4	0.7	0.7	1.7	-0.9	1.0
Tanning	0.0	0.5	1.6	1.0	0.6	0.8	0.5	0.6	1.0	0.8	0.2	-0.8	0.5	1.2	0.6	-0.7	-0.7	-0.2	0.3	-0.7

Hub : Genes

CCDC152

Models

Trait associations